Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
| Domain Name | Pfam ID | Position | E-value | Description |
|---|---|---|---|---|
| IMPDH | PF00478 | 29 - 97 | 3.3e-24 | IMP dehydrogenase / GMP reductase domain |
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No orthologs found for this gene in the current database.
| Enzyme | Recognition Site | Cut Count | Positions (bp) |
|---|---|---|---|
| AccB1I | GGYRCC | 1 cut(s) | 29 |
| AccB7I | CCANNNNNTGG | 1 cut(s) | 51 |
| AciI | CCGC | 1 cut(s) | 27 |
| AcsI | RAATTY | 1 cut(s) | 193 |
| AfaI | GTAC | 3 cut(s) | 125, 140, 253 |
| AfiI | CCNNNNNNNGG | 2 cut(s) | 51, 279 |
| AhdI | GACNNNNNGTC | 1 cut(s) | 180 |
| AluBI | AGCT | 1 cut(s) | 87 |
| AluI | AGCT | 1 cut(s) | 87 |
| Alw21I | GWGCWC | 2 cut(s) | 63, 75 |
| ApoI | RAATTY | 1 cut(s) | 193 |
| AspLEI | GCGC | 1 cut(s) | 272 |
| AsuHPI | GGTGA | 1 cut(s) | 184 |
| BanI | GGYRCC | 1 cut(s) | 29 |
| Bbv12I | GWGCWC | 2 cut(s) | 63, 75 |
| BccI | CCATC | 2 cut(s) | 209, 226 |
| BceAI | ACGGC | 2 cut(s) | 91, 257 |
| BclI | TGATCA | 1 cut(s) | 117 |
| BisI | GCNGC | 1 cut(s) | 28 |
| BlsI | GCNGC | 1 cut(s) | 29 |
| BmeRI | GACNNNNNGTC | 1 cut(s) | 180 |
| BmiI | GGNNCC | 3 cut(s) | 31, 43, 244 |
| BmsI | GCATC | 1 cut(s) | 87 |
| BpuEI | CTTGAG | 1 cut(s) | 243 |
| BsaJI | CCNNGG | 1 cut(s) | 22 |
| Bsc4I | CCNNNNNNNGG | 2 cut(s) | 51, 279 |
| BseDI | CCNNGG | 1 cut(s) | 22 |
| BseGI | GGATG | 3 cut(s) | 18, 157, 237 |
| BseLI | CCNNNNNNNGG | 2 cut(s) | 51, 279 |
| BseMII | CTCAG | 1 cut(s) | 156 |
| BshNI | GGYRCC | 1 cut(s) | 29 |
| BsiHKAI | GWGCWC | 2 cut(s) | 63, 75 |
| BslI | CCNNNNNNNGG | 2 cut(s) | 51, 279 |
| Bsp1286I | GDGCHC | 2 cut(s) | 63, 75 |
| Bsp143I | GATC | 1 cut(s) | 117 |
| BspACI | CCGC | 1 cut(s) | 27 |
| BspCNI | CTCAG | 1 cut(s) | 155 |
| BspLI | GGNNCC | 3 cut(s) | 31, 43, 244 |
| BspT107I | GGYRCC | 1 cut(s) | 29 |
| BssECI | CCNNGG | 1 cut(s) | 22 |
| BssMI | GATC | 1 cut(s) | 117 |
| BssT1I | CCWWGG | 1 cut(s) | 22 |
| Bst4CI | ACNGT | 1 cut(s) | 178 |
| BstDEI | CTNAG | 1 cut(s) | 142 |
| BstF5I | GGATG | 3 cut(s) | 18, 157, 237 |
| BstHHI | GCGC | 1 cut(s) | 272 |
| BstKTI | GATC | 1 cut(s) | 120 |
| BstMBI | GATC | 1 cut(s) | 117 |
| BstMWI | GCNNNNNNNGC | 2 cut(s) | 84, 276 |
| BtsCI | GGATG | 3 cut(s) | 18, 157, 237 |
| CfoI | GCGC | 1 cut(s) | 272 |
| Csp6I | GTAC | 3 cut(s) | 124, 139, 252 |
| CviJI | RGCY | 4 cut(s) | 44, 87, 206, 243 |
| CviKI_1 | RGCY | 4 cut(s) | 44, 87, 206, 243 |
| CviQI | GTAC | 3 cut(s) | 124, 139, 252 |
| DdeI | CTNAG | 1 cut(s) | 142 |
| DpnI | GATC | 1 cut(s) | 119 |
| DpnII | GATC | 1 cut(s) | 117 |
| DriI | GACNNNNNGTC | 1 cut(s) | 180 |
| Eam1105I | GACNNNNNGTC | 1 cut(s) | 180 |
| Eco130I | CCWWGG | 1 cut(s) | 22 |
| EcoT14I | CCWWGG | 1 cut(s) | 22 |
| ErhI | CCWWGG | 1 cut(s) | 22 |
| FaiI | YATR | 2 cut(s) | 36, 292 |
| FbaI | TGATCA | 1 cut(s) | 117 |
| Fnu4HI | GCNGC | 1 cut(s) | 28 |
| FokI | GGATG | 3 cut(s) | 5, 164, 244 |
| Fsp4HI | GCNGC | 1 cut(s) | 28 |
| GlaI | GCGC | 1 cut(s) | 271 |
| GluI | GCNGC | 1 cut(s) | 28 |
| HhaI | GCGC | 1 cut(s) | 272 |
| Hin6I | GCGC | 1 cut(s) | 270 |
| HinP1I | GCGC | 1 cut(s) | 270 |
| HinfI | GANTC | 3 cut(s) | 10, 181, 199 |
| HphI | GGTGA | 1 cut(s) | 184 |
| Hpy188I | TCNGA | 2 cut(s) | 108, 145 |
| Hpy188III | TCNNGA | 2 cut(s) | 130, 260 |
| Hpy99I | CGWCG | 1 cut(s) | 278 |
| HpyCH4III | ACNGT | 1 cut(s) | 178 |
| HpyF10VI | GCNNNNNNNGC | 2 cut(s) | 84, 276 |
| HpyF3I | CTNAG | 1 cut(s) | 142 |
| HspAI | GCGC | 1 cut(s) | 270 |
| Ksp22I | TGATCA | 1 cut(s) | 117 |
| Kzo9I | GATC | 1 cut(s) | 117 |
| LmnI | GCTCC | 2 cut(s) | 41, 248 |
| LpnPI | CCDG | 7 cut(s) | 37, 170, 188, 192, 225, 265, 272 |
| LweI | GCATC | 1 cut(s) | 87 |
| MaeIII | GTNAC | 1 cut(s) | 172 |
| MalI | GATC | 1 cut(s) | 119 |
| MboI | GATC | 1 cut(s) | 117 |
| MhlI | GDGCHC | 2 cut(s) | 63, 75 |
| MluCI | AATT | 1 cut(s) | 193 |
| MlyI | GAGTC | 1 cut(s) | 190 |
| MnlI | CCTC | 3 cut(s) | 49, 216, 256 |
| MwoI | GCNNNNNNNGC | 2 cut(s) | 84, 276 |
| NdeII | GATC | 1 cut(s) | 117 |
| NlaIV | GGNNCC | 3 cut(s) | 31, 43, 244 |
| NmuCI | GTSAC | 1 cut(s) | 172 |
| PfeI | GAWTC | 2 cut(s) | 10, 199 |
| PflMI | CCANNNNNTGG | 1 cut(s) | 51 |
| PkrI | GCNGC | 1 cut(s) | 29 |
| PleI | GAGTC | 1 cut(s) | 189 |
| PpsI | GAGTC | 1 cut(s) | 189 |
| PspN4I | GGNNCC | 3 cut(s) | 31, 43, 244 |
| RsaI | GTAC | 3 cut(s) | 125, 140, 253 |
| RsaNI | GTAC | 3 cut(s) | 124, 139, 252 |
| SatI | GCNGC | 1 cut(s) | 28 |
| Sau3AI | GATC | 1 cut(s) | 117 |
| SchI | GAGTC | 1 cut(s) | 190 |
| SduI | GDGCHC | 2 cut(s) | 63, 75 |
| SetI | ASST | 4 cut(s) | 60, 89, 267, 291 |
| SfaNI | GCATC | 1 cut(s) | 87 |
| SmlI | CTYRAG | 1 cut(s) | 258 |
| SmoI | CTYRAG | 1 cut(s) | 258 |
| Sse9I | AATT | 1 cut(s) | 193 |
| SsiI | CCGC | 1 cut(s) | 27 |
| StyI | CCWWGG | 1 cut(s) | 22 |
| TaaI | ACNGT | 1 cut(s) | 178 |
| TaqI | TCGA | 1 cut(s) | 69 |
| TasI | AATT | 1 cut(s) | 193 |
| TatI | WGTACW | 3 cut(s) | 123, 138, 251 |
| TauI | GCSGC | 1 cut(s) | 30 |
| TfiI | GAWTC | 2 cut(s) | 10, 199 |
| TseFI | GTSAC | 1 cut(s) | 172 |
| Tsp45I | GTSAC | 1 cut(s) | 172 |
| Van91I | CCANNNNNTGG | 1 cut(s) | 51 |
| XapI | RAATTY | 1 cut(s) | 193 |