Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis
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| Species | Orthologous Gene IDs |
|---|---|
| rosa_chinensis | RchiOBHm_Chr2g0097681 |
| rosa_rugosa | Rorug05G0570700.1 |
| rosa_samantha | Rh2DG118700 Rh7DG285100 |
| Enzyme | Recognition Site | Cut Count | Positions (bp) |
|---|---|---|---|
| AanI | TTATAA | 1 cut(s) | 122 |
| AclWI | GGATC | 1 cut(s) | 151 |
| AluBI | AGCT | 1 cut(s) | 248 |
| AluI | AGCT | 1 cut(s) | 248 |
| Alw21I | GWGCWC | 1 cut(s) | 57 |
| Alw26I | GTCTC | 1 cut(s) | 132 |
| AlwI | GGATC | 1 cut(s) | 151 |
| AspS9I | GGNCC | 1 cut(s) | 64 |
| AvaII | GGWCC | 1 cut(s) | 64 |
| Bbv12I | GWGCWC | 1 cut(s) | 57 |
| BcoDI | GTCTC | 1 cut(s) | 132 |
| BfaI | CTAG | 1 cut(s) | 203 |
| Bme18I | GGWCC | 1 cut(s) | 64 |
| BmgT120I | GGNCC | 1 cut(s) | 64 |
| BmiI | GGNNCC | 1 cut(s) | 253 |
| BpuEI | CTTGAG | 1 cut(s) | 179 |
| BsaJI | CCNNGG | 2 cut(s) | 96, 255 |
| Bse3DI | GCAATG | 1 cut(s) | 43 |
| BseDI | CCNNGG | 2 cut(s) | 96, 255 |
| BseGI | GGATG | 1 cut(s) | 186 |
| BseMI | GCAATG | 1 cut(s) | 43 |
| BseMII | CTCAG | 2 cut(s) | 72, 244 |
| BsiHKAI | GWGCWC | 1 cut(s) | 57 |
| BslFI | GGGAC | 1 cut(s) | 273 |
| BsmAI | GTCTC | 1 cut(s) | 132 |
| BsmBI | CGTCTC | 1 cut(s) | 132 |
| BsmFI | GGGAC | 1 cut(s) | 273 |
| Bsp1286I | GDGCHC | 1 cut(s) | 57 |
| Bsp143I | GATC | 1 cut(s) | 143 |
| Bsp19I | CCATGG | 1 cut(s) | 96 |
| BspCNI | CTCAG | 2 cut(s) | 71, 243 |
| BspLI | GGNNCC | 1 cut(s) | 253 |
| BspPI | GGATC | 1 cut(s) | 151 |
| BsrDI | GCAATG | 1 cut(s) | 43 |
| BssECI | CCNNGG | 2 cut(s) | 96, 255 |
| BssMI | GATC | 1 cut(s) | 143 |
| BssT1I | CCWWGG | 2 cut(s) | 96, 255 |
| BstDEI | CTNAG | 3 cut(s) | 58, 230, 309 |
| BstDSI | CCRYGG | 1 cut(s) | 96 |
| BstF5I | GGATG | 1 cut(s) | 186 |
| BstKTI | GATC | 1 cut(s) | 146 |
| BstMAI | GTCTC | 1 cut(s) | 132 |
| BstMBI | GATC | 1 cut(s) | 143 |
| BstMWI | GCNNNNNNNGC | 1 cut(s) | 101 |
| BtgI | CCRYGG | 1 cut(s) | 96 |
| BtsCI | GGATG | 1 cut(s) | 186 |
| Cfr13I | GGNCC | 1 cut(s) | 64 |
| CviAII | CATG | 2 cut(s) | 97, 242 |
| CviJI | RGCY | 1 cut(s) | 248 |
| CviKI_1 | RGCY | 1 cut(s) | 248 |
| DdeI | CTNAG | 3 cut(s) | 58, 230, 309 |
| DpnI | GATC | 1 cut(s) | 145 |
| DpnII | GATC | 1 cut(s) | 143 |
| Eco130I | CCWWGG | 2 cut(s) | 96, 255 |
| Eco47I | GGWCC | 1 cut(s) | 64 |
| EcoO109I | RGGNCCY | 1 cut(s) | 64 |
| EcoT14I | CCWWGG | 2 cut(s) | 96, 255 |
| ErhI | CCWWGG | 2 cut(s) | 96, 255 |
| Esp3I | CGTCTC | 1 cut(s) | 132 |
| FaeI | CATG | 2 cut(s) | 100, 245 |
| FaqI | GGGAC | 1 cut(s) | 273 |
| FatI | CATG | 2 cut(s) | 96, 241 |
| FauNDI | CATATG | 1 cut(s) | 85 |
| FokI | GGATG | 1 cut(s) | 193 |
| FspBI | CTAG | 1 cut(s) | 203 |
| Hin1II | CATG | 2 cut(s) | 100, 245 |
| HinfI | GANTC | 2 cut(s) | 89, 228 |
| Hpy188I | TCNGA | 3 cut(s) | 61, 233, 306 |
| Hpy188III | TCNNGA | 1 cut(s) | 196 |
| HpyCH4IV | ACGT | 1 cut(s) | 133 |
| HpyCH4V | TGCA | 1 cut(s) | 31 |
| HpyF10VI | GCNNNNNNNGC | 1 cut(s) | 101 |
| HpyF3I | CTNAG | 3 cut(s) | 58, 230, 309 |
| HpySE526I | ACGT | 1 cut(s) | 133 |
| Hsp92II | CATG | 2 cut(s) | 100, 245 |
| Kzo9I | GATC | 1 cut(s) | 143 |
| LpnPI | CCDG | 2 cut(s) | 234, 248 |
| MaeI | CTAG | 1 cut(s) | 203 |
| MaeII | ACGT | 1 cut(s) | 133 |
| MalI | GATC | 1 cut(s) | 145 |
| MboI | GATC | 1 cut(s) | 143 |
| MboII | GAAGA | 1 cut(s) | 263 |
| MhlI | GDGCHC | 1 cut(s) | 57 |
| MluCI | AATT | 2 cut(s) | 170, 234 |
| MlyI | GAGTC | 1 cut(s) | 222 |
| MnlI | CCTC | 5 cut(s) | 55, 81, 121, 171, 218 |
| MwoI | GCNNNNNNNGC | 1 cut(s) | 101 |
| NcoI | CCATGG | 1 cut(s) | 96 |
| NdeI | CATATG | 1 cut(s) | 85 |
| NdeII | GATC | 1 cut(s) | 143 |
| NlaIII | CATG | 2 cut(s) | 100, 245 |
| NlaIV | GGNNCC | 1 cut(s) | 253 |
| PfeI | GAWTC | 1 cut(s) | 89 |
| PleI | GAGTC | 1 cut(s) | 222 |
| PpsI | GAGTC | 1 cut(s) | 222 |
| PpuMI | RGGWCCY | 1 cut(s) | 64 |
| PsiI | TTATAA | 1 cut(s) | 122 |
| Psp5II | RGGWCCY | 1 cut(s) | 64 |
| PspN4I | GGNNCC | 1 cut(s) | 253 |
| PspPI | GGNCC | 1 cut(s) | 64 |
| PspPPI | RGGWCCY | 1 cut(s) | 64 |
| Sau3AI | GATC | 1 cut(s) | 143 |
| Sau96I | GGNCC | 1 cut(s) | 64 |
| SchI | GAGTC | 1 cut(s) | 222 |
| SduI | GDGCHC | 1 cut(s) | 57 |
| SetI | ASST | 5 cut(s) | 69, 73, 136, 250, 267 |
| SinI | GGWCC | 1 cut(s) | 64 |
| SmlI | CTYRAG | 2 cut(s) | 12, 194 |
| SmoI | CTYRAG | 2 cut(s) | 12, 194 |
| Sse9I | AATT | 2 cut(s) | 170, 234 |
| SspMI | CTAG | 1 cut(s) | 203 |
| StyI | CCWWGG | 2 cut(s) | 96, 255 |
| TaiI | ACGT | 1 cut(s) | 136 |
| TasI | AATT | 2 cut(s) | 170, 234 |
| TfiI | GAWTC | 1 cut(s) | 89 |
| TspDTI | ATGAA | 3 cut(s) | 102, 180, 230 |
| TspGWI | ACGGA | 1 cut(s) | 156 |
| VpaK11BI | GGWCC | 1 cut(s) | 64 |
| XspI | CTAG | 1 cut(s) | 203 |