MD08G1055000.v1.1

Folate-Biopterin Transporter

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
malus_domestica
Chr08
OG0021882
Physical Location & Seq
Reverse (-)
4298637 .. 4301610
2974 bp
Loading structure...
UTR
Exon/CDS
Intron
MD08G1055000.v1.1.491

Sequence Viewer

Length: 1530 bp
ATGGATGATTACTCCTCTCAAGAAACCCAGAAAACAACCACCTCAAACCGAAACGTCGATGATCAAGACGATCACCACCATCCAAATCCCACCAACCCATTTGTCCAAATCCTCCAACAACCAATCCAATGGCTCCAAATGCTCTCCTCAGAGCTAAACCCTACCTTTGTCCTGGGTGTGGTTCTTGTTTACGGACTCAGCCAGGGCTTCTCAGGCTCTTATTTCAAAGTGGTCACGGACTACTACTGGAAAGACGTCCAGAAACTCCAGCCCTCTGTTGTCCAGCTTTACATTGGACTGTACTATATTCCGTGGCTCATGAAGCCGGTTTGGGGCTTGTTGACCGACGTTTTTCCAGTCCGGGGATACAGAAGGCGGCCTTATTTTGTTCTGGCCGGAGTTATAGGGACAGTTTCAGCTCTCACGGTTGCATTCAGTGGGAACTTGGCTGCTGTGGTGGCATTGACTTGGTTGATCGGTGTCACGGCAGGTGTGGCGATTGCGGATGTCACGATCGACGCGTGTATAGCCCGGAATAGTATTGAGATACGGTCGTTGGCTTCGGATTTGCAGAGCCTTTGTGGTTTCTGCTCTTCTGCTGGTGCTCTGGTTGGGTACTCTACTAGTGGGTTTTTTGTTCATCATCTTGGTCCTCAGGGTGCATTGATTCTTTTGGCAATCCCACCAATCTTTCTAACTGTTCTGGGCTTTGTTATATATGAACAAAGATCAACCAACCTTCACTCTCAGAGGAAGAGGGCAGTGGAAGAAGTGGGAGTGGCAATGAGCGGAATGTACAAAACAATCAAACTACCTCAGGTGTGGAAACCTTCCCTTTACATGTACCTCTCCTTGGCCCTCAGTATTAACACTCAGGAAGGTAATTTTTATTGGTACACTGACCCTTCAGCTGGCCCTGCATTCTCTCAGGAGTTTGTTGGGATGATTTATGCAGTTGGTGCAGTGGCTTCGATAGTAGGAGTTCTGATCTACCACAAGACTCTGAAAAACTACCCTTTTCGGAACCTGGTCTTCTTTGCTCAACTTCTCTACGCCATGTCCGGACTTCTCGACCTAACTTTCATCCTAAGGTGGAACCTAGCTCTAGGCATTCCCGACTACTTCTTTGTGATCATGGAAGAATGCGTGTTTCGAATCGTTACCAAGATCCGATGGATGCCCATGATCGTACTGAGCACGAGGCTCTGCCCTCTAGGCATCGAGGGCACGTTCTTCGCGCTGTTGATGTGTATCGACAGCCTTGGCTCGCTGTCGTCGAAATGGGGTGGAGGAGCAGTGCTTCATGCCTTGAATGTCACAAGGACTAATTTTACAAACTTGTGGCTGGCCCTTCTGATTAGAAATGTGTTGAGATTTTTGACTCTTGGTTTGATTTTCTTGGTTCCCAAGGCTGATCAGCTTGATCTGTTGATTCCTTCTGATCTTTTGACCAAGAATTCTTTTGAATTTAGTGATGTGGATGATCAGAGCTTGGAATTGGTCCCATCCAAGGGGAAGATTGAAGTTTAG
Functional Annotation
Gene Ontology
Molecular Function
Biological Process
Cellular Component
No ontology terms assigned.
KEGG Pathways
Metabolic & Signaling
No pathways identified.
Pfam Domains
Protein Families
BT1

Protein Analysis

510

Amino Acids

56.7

Weight (kDa)

6.71

Isoelectric Point (pI)

41.96

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
BT1 PF03092 68 - 475 1.2e-106 BT1 family
MFS_1 PF07690 70 - 423 3.6e-12 Major Facilitator Superfamily
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
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Publication-ready
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Orthologous Genes (Group: OG0021882)

Species Orthologous Gene IDs
arabidopsis_thaliana AT5G10820
malus_domestica MD08G1055000.v1.1
prunus_persica Prupe.1G395300_v2.0.a1
pyrus_communis pycom08g04530

Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AarI CACCTGC 1 cut(s) 479
AatII GACGTC 1 cut(s) 258
Acc36I ACCTGC 1 cut(s) 479
AccBSI CCGCTC 1 cut(s) 789
AccII CGCG 2 cut(s) 521, 1238
AccIII TCCGGA 1 cut(s) 1061
AciI CCGC 3 cut(s) 376, 503, 789
AclWI GGATC 1 cut(s) 1162
AcoI YGGCCR 1 cut(s) 393
AcsI RAATTY 2 cut(s) 1456, 1466
AcuI CTGAAG 1 cut(s) 891
AcyI GRCGYC 1 cut(s) 255
AfaI GTAC 6 cut(s) 302, 617, 797, 845, 896, 1191
AfiI CCNNNNNNNGG 7 cut(s) 178, 332, 362, 853, 911, 1510, 1511
AflIII ACRYGT 2 cut(s) 519, 840
AgsI TTSAA 4 cut(s) 226, 1312, 1466, 1523
AhlI ACTAGT 1 cut(s) 623
AjnI CCWGG 3 cut(s) 171, 201, 1026
AluBI AGCT 7 cut(s) 154, 286, 419, 911, 1103, 1420, 1491
AluI AGCT 7 cut(s) 154, 286, 419, 911, 1103, 1420, 1491
Alw21I GWGCWC 2 cut(s) 607, 1199
AlwI GGATC 1 cut(s) 1162
Aor13HI TCCGGA 1 cut(s) 1061
AoxI GGCC 5 cut(s) 377, 393, 855, 913, 1347
ApeKI GCWGC 1 cut(s) 449
ApoI RAATTY 2 cut(s) 1456, 1466
ArsI GACNNNNNNTTYG 4 cut(s) 1109, 1141, 1372, 1404
AspLEI GCGC 1 cut(s) 1240
AspS9I GGNCC 5 cut(s) 650, 856, 914, 1348, 1501
AsuC2I CCSGG 2 cut(s) 362, 532
AsuHPI GGTGA 1 cut(s) 65
AsuII TTCGAA 1 cut(s) 1153
AvaII GGWCC 2 cut(s) 650, 1501
AxyI CCTNAGG 3 cut(s) 654, 816, 1088
BaeGI GKGCMC 1 cut(s) 1229
BaeI ACNNNNGTAYC 2 cut(s) 539, 572
BauI CACGAG 1 cut(s) 1198
BbsI GAAGAC 1 cut(s) 1024
Bbv12I GWGCWC 2 cut(s) 607, 1199
BbvI GCAGC 1 cut(s) 436
BccI CCATC 3 cut(s) 87, 1167, 1513
BceAI ACGGC 1 cut(s) 501
BcgI CGANNNNNNTGC 4 cut(s) 951, 985, 1216, 1250
BciT130I CCWGG 3 cut(s) 173, 203, 1028
BciVI GTATCC 1 cut(s) 359
BclI TGATCA 4 cut(s) 61, 1131, 1414, 1483
BcnI CCSGG 2 cut(s) 362, 532
BcuI ACTAGT 1 cut(s) 623
BfaI CTAG 4 cut(s) 624, 1100, 1106, 1214
BfuAI ACCTGC 1 cut(s) 479
BfuI GTATCC 1 cut(s) 359
BglI GCCNNNNNGGC 1 cut(s) 1215
BisI GCNGC 2 cut(s) 377, 450
BlsI GCNGC 2 cut(s) 378, 451
Bme1390I CCNGG 5 cut(s) 173, 203, 362, 532, 1028
Bme18I GGWCC 2 cut(s) 650, 1501
BmgT120I GGNCC 5 cut(s) 650, 856, 914, 1348, 1501
BmiI GGNNCC 5 cut(s) 134, 1025, 1097, 1404, 1503
BmrFI CCNGG 5 cut(s) 173, 203, 362, 532, 1028
BmsI GCATC 2 cut(s) 1167, 1227
BpiI GAAGAC 1 cut(s) 1024
BpmI CTGGAG 1 cut(s) 251
Bpu14I TTCGAA 1 cut(s) 1153
BpuMI CCSGG 2 cut(s) 362, 532
BsaBI GATNNNNATC 1 cut(s) 1250
BsaHI GRCGYC 1 cut(s) 255
BsaJI CCNNGG 8 cut(s) 172, 202, 311, 361, 852, 1261, 1407, 1509
BsaWI WCCGGW 1 cut(s) 1061
BsaXI ACNNNNNCTCC 2 cut(s) 1281, 1311
Bsc4I CCNNNNNNNGG 7 cut(s) 178, 332, 362, 853, 911, 1510, 1511
Bse118I RCCGGY 1 cut(s) 325
Bse1I ACTGG 2 cut(s) 251, 356
Bse21I CCTNAGG 3 cut(s) 654, 816, 1088
Bse3DI GCAATG 1 cut(s) 789
Bse8I GATNNNNATC 1 cut(s) 1250
BseAI TCCGGA 1 cut(s) 1061
BseBI CCWGG 3 cut(s) 173, 203, 1028
BseDI CCNNGG 8 cut(s) 172, 202, 311, 361, 852, 1261, 1407, 1509
BseGI GGATG 8 cut(s) 10, 79, 511, 948, 1083, 1182, 1486, 1505
BseJI GATNNNNATC 1 cut(s) 1250
BseLI CCNNNNNNNGG 7 cut(s) 178, 332, 362, 853, 911, 1510, 1511
BseMI GCAATG 1 cut(s) 789
BseNI ACTGG 2 cut(s) 251, 356
BseRI GAGGAG 3 cut(s) 4, 136, 1305
BseSI GKGCMC 1 cut(s) 1229
BseXI GCAGC 1 cut(s) 436
BsgI GTGCAG 1 cut(s) 981
Bsh1236I CGCG 2 cut(s) 521, 1238
Bsh1285I CGRYCG 2 cut(s) 516, 554
BshFI GGCC 5 cut(s) 379, 395, 857, 915, 1349
BsiEI CGRYCG 2 cut(s) 516, 554
BsiHKAI GWGCWC 2 cut(s) 607, 1199
BsiSI CCGG 5 cut(s) 326, 361, 396, 532, 1062
BslFI GGGAC 2 cut(s) 421, 1487
BslI CCNNNNNNNGG 7 cut(s) 178, 332, 362, 853, 911, 1510, 1511
BsmFI GGGAC 2 cut(s) 421, 1487
BsmI GAATGC 4 cut(s) 431, 920, 1110, 1148
BsnI GGCC 5 cut(s) 379, 395, 857, 915, 1349
Bsp119I TTCGAA 1 cut(s) 1153
Bsp1286I GDGCHC 3 cut(s) 607, 1199, 1229
Bsp13I TCCGGA 1 cut(s) 1061
Bsp1407I TGTACA 1 cut(s) 795
BspACI CCGC 3 cut(s) 376, 503, 789
BspANI GGCC 5 cut(s) 379, 395, 857, 915, 1349
BspEI TCCGGA 1 cut(s) 1061
BspFNI CGCG 2 cut(s) 521, 1238
BspHI TCATGA 1 cut(s) 318
BspLI GGNNCC 5 cut(s) 134, 1025, 1097, 1404, 1503
BspMI ACCTGC 1 cut(s) 479
BspPI GGATC 1 cut(s) 1162
BspQI GCTCTTC 1 cut(s) 598
BspT104I TTCGAA 1 cut(s) 1153
BsrBI CCGCTC 1 cut(s) 789
BsrDI GCAATG 1 cut(s) 789
BsrFI RCCGGY 1 cut(s) 325
BsrGI TGTACA 1 cut(s) 795
BsrI ACTGG 2 cut(s) 251, 356
BssAI RCCGGY 1 cut(s) 325
BssECI CCNNGG 8 cut(s) 172, 202, 311, 361, 852, 1261, 1407, 1509
BssNI GRCGYC 1 cut(s) 255
BssSI CACGAG 1 cut(s) 1198
BssT1I CCWWGG 4 cut(s) 852, 1261, 1407, 1509
Bst2BI CACGAG 1 cut(s) 1198
Bst2UI CCWGG 3 cut(s) 173, 203, 1028
Bst4CI ACNGT 5 cut(s) 300, 412, 427, 552, 700
Bst6I CTCTTC 2 cut(s) 598, 749
BstACI GRCGYC 1 cut(s) 255
BstAPI GCANNNNNTGC 1 cut(s) 959
BstAUI TGTACA 1 cut(s) 795
BstBI TTCGAA 1 cut(s) 1153
BstC8I GCNNGC 3 cut(s) 913, 1268, 1347
BstDSI CCRYGG 1 cut(s) 311
BstF5I GGATG 8 cut(s) 10, 79, 511, 948, 1083, 1182, 1486, 1505
BstFNI CGCG 2 cut(s) 521, 1238
BstHHI GCGC 1 cut(s) 1240
BstMCI CGRYCG 2 cut(s) 516, 554
BstNI CCWGG 3 cut(s) 173, 203, 1028
BstNSI RCATGY 1 cut(s) 844
BstSCI CCNGG 5 cut(s) 171, 201, 360, 530, 1026
BstSLI GKGCMC 1 cut(s) 1229
BstUI CGCG 2 cut(s) 521, 1238
BstV1I GCAGC 1 cut(s) 436
BstV2I GAAGAC 1 cut(s) 1024
BstX2I RGATCY 1 cut(s) 1167
BstXI CCANNNNNNTGG 1 cut(s) 129
BstYI RGATCY 1 cut(s) 1167
Bsu36I CCTNAGG 3 cut(s) 654, 816, 1088
BsuI GTATCC 1 cut(s) 359
BsuRI GGCC 5 cut(s) 379, 395, 857, 915, 1349
BtgI CCRYGG 1 cut(s) 311
BtsCI GGATG 8 cut(s) 10, 79, 511, 948, 1083, 1182, 1486, 1505
BtsI GCAGTG 3 cut(s) 768, 969, 1302
BtsIMutI CAGTG 5 cut(s) 442, 768, 897, 969, 1302
BveI ACCTGC 1 cut(s) 479
Cac8I GCNNGC 3 cut(s) 913, 1268, 1347
CciI TCATGA 1 cut(s) 318
CfoI GCGC 1 cut(s) 1240
Cfr10I RCCGGY 1 cut(s) 325
Cfr13I GGNCC 5 cut(s) 650, 856, 914, 1348, 1501
CseI GACGC 1 cut(s) 527
CsiI ACCWGGT 1 cut(s) 1026
Csp6I GTAC 6 cut(s) 301, 616, 796, 844, 895, 1190
CviAII CATG 6 cut(s) 319, 841, 1057, 1135, 1183, 1304
CviQI GTAC 6 cut(s) 301, 616, 796, 844, 895, 1190
EaeI YGGCCR 1 cut(s) 393
Eam1104I CTCTTC 2 cut(s) 598, 749
EarI CTCTTC 2 cut(s) 598, 749
Eco130I CCWWGG 4 cut(s) 852, 1261, 1407, 1509
Eco47I GGWCC 2 cut(s) 650, 1501
Eco57I CTGAAG 1 cut(s) 891
Eco81I CCTNAGG 3 cut(s) 654, 816, 1088
EcoRI GAATTC 1 cut(s) 1456
EcoRII CCWGG 3 cut(s) 171, 201, 1026
EcoT14I CCWWGG 4 cut(s) 852, 1261, 1407, 1509
ErhI CCWWGG 4 cut(s) 852, 1261, 1407, 1509
FaeI CATG 6 cut(s) 322, 844, 1060, 1138, 1186, 1307
FalI AAGNNNNNCTT 2 cut(s) 364, 396
FaqI GGGAC 2 cut(s) 421, 1487
FatI CATG 6 cut(s) 318, 840, 1056, 1134, 1182, 1303
FbaI TGATCA 4 cut(s) 61, 1131, 1414, 1483
Fnu4HI GCNGC 2 cut(s) 377, 450
FokI GGATG 8 cut(s) 17, 66, 518, 955, 1070, 1189, 1492, 1493
Fsp4HI GCNGC 2 cut(s) 377, 450
FspBI CTAG 4 cut(s) 624, 1100, 1106, 1214
GlaI GCGC 1 cut(s) 1239
GluI GCNGC 2 cut(s) 377, 450
GsuI CTGGAG 1 cut(s) 251
HaeIII GGCC 5 cut(s) 379, 395, 857, 915, 1349
HapII CCGG 5 cut(s) 326, 361, 396, 532, 1062
HgaI GACGC 1 cut(s) 527
HhaI GCGC 1 cut(s) 1240
Hin1I GRCGYC 1 cut(s) 255
Hin1II CATG 6 cut(s) 322, 844, 1060, 1138, 1186, 1307
Hin6I GCGC 1 cut(s) 1238
HinP1I GCGC 1 cut(s) 1238
HincII GTYRAC 1 cut(s) 342
HindII GTYRAC 1 cut(s) 342
HinfI GANTC 6 cut(s) 195, 667, 1000, 1155, 1381, 1432
HpaII CCGG 5 cut(s) 326, 361, 396, 532, 1062
HphI GGTGA 1 cut(s) 65
Hpy166II GTNNAC 3 cut(s) 190, 342, 897
Hpy8I GTNNAC 3 cut(s) 190, 342, 897
Hpy99I CGWCG 4 cut(s) 59, 350, 521, 1279
HpyAV CCTTC 7 cut(s) 366, 749, 840, 872, 915, 1361, 1446
HpyCH4III ACNGT 5 cut(s) 300, 412, 427, 552, 700
HpyCH4IV ACGT 4 cut(s) 54, 255, 348, 1229
HpyCH4V TGCA 6 cut(s) 431, 571, 662, 920, 953, 962
HpySE526I ACGT 4 cut(s) 54, 255, 348, 1229
Hsp92I GRCGYC 1 cut(s) 255
Hsp92II CATG 6 cut(s) 322, 844, 1060, 1138, 1186, 1307
HspAI GCGC 1 cut(s) 1238
Kpn2I TCCGGA 1 cut(s) 1061
Ksp22I TGATCA 4 cut(s) 61, 1131, 1414, 1483
LguI GCTCTTC 1 cut(s) 598
LmnI GCTCC 2 cut(s) 138, 1292
Lsp1109I GCAGC 1 cut(s) 436
LweI GCATC 2 cut(s) 1167, 1227
MabI ACCWGGT 1 cut(s) 1026
MaeI CTAG 4 cut(s) 624, 1100, 1106, 1214
MaeII ACGT 4 cut(s) 54, 255, 348, 1229
MaeIII GTNAC 5 cut(s) 232, 481, 508, 1159, 1315
MbiI CCGCTC 1 cut(s) 789
MboII GAAGA 7 cut(s) 585, 766, 779, 1024, 1151, 1225, 1528
MflI RGATCY 1 cut(s) 1167
MhlI GDGCHC 3 cut(s) 607, 1199, 1229
MluCI AATT 5 cut(s) 883, 1327, 1456, 1466, 1496
MluI ACGCGT 1 cut(s) 519
MlyI GAGTC 3 cut(s) 189, 994, 1375
MmeI TCCRAC 1 cut(s) 139
MroI TCCGGA 1 cut(s) 1061
MseI TTAA 1 cut(s) 867
MspA1I CMGCKG 1 cut(s) 911
MspI CCGG 5 cut(s) 326, 361, 396, 532, 1062
MspR9I CCNGG 5 cut(s) 173, 203, 362, 532, 1028
Mva1269I GAATGC 4 cut(s) 431, 920, 1110, 1148
MvaI CCWGG 3 cut(s) 173, 203, 1028
MvnI CGCG 2 cut(s) 521, 1238
NciI CCSGG 2 cut(s) 362, 532
NlaIII CATG 6 cut(s) 322, 844, 1060, 1138, 1186, 1307
NlaIV GGNNCC 5 cut(s) 134, 1025, 1097, 1404, 1503
NmuCI GTSAC 4 cut(s) 232, 481, 508, 1315
NspI RCATGY 1 cut(s) 844
NspV TTCGAA 1 cut(s) 1153
PagI TCATGA 1 cut(s) 318
PaqCI CACCTGC 1 cut(s) 479
PciI ACATGT 1 cut(s) 840
PciSI GCTCTTC 1 cut(s) 598
PcsI WCGNNNNNNNCGW 2 cut(s) 518, 1274
PctI GAATGC 4 cut(s) 431, 920, 1110, 1148
PfeI GAWTC 3 cut(s) 667, 1155, 1432
PkrI GCNGC 2 cut(s) 378, 451
Ple19I CGATCG 1 cut(s) 516
PleI GAGTC 3 cut(s) 189, 994, 1375
PpsI GAGTC 3 cut(s) 189, 994, 1375
PscI ACATGT 1 cut(s) 840
Psp6I CCWGG 3 cut(s) 171, 201, 1026
PspGI CCWGG 3 cut(s) 171, 201, 1026
PspN4I GGNNCC 5 cut(s) 134, 1025, 1097, 1404, 1503
PspPI GGNCC 5 cut(s) 650, 856, 914, 1348, 1501
PsuI RGATCY 1 cut(s) 1167
PvuI CGATCG 1 cut(s) 516
PvuII CAGCTG 1 cut(s) 911
RsaI GTAC 6 cut(s) 302, 617, 797, 845, 896, 1191
RsaNI GTAC 6 cut(s) 301, 616, 796, 844, 895, 1190
SapI GCTCTTC 1 cut(s) 598
SaqAI TTAA 1 cut(s) 867
SatI GCNGC 2 cut(s) 377, 450
Sau96I GGNCC 5 cut(s) 650, 856, 914, 1348, 1501
SchI GAGTC 3 cut(s) 189, 994, 1375
ScrFI CCNGG 5 cut(s) 173, 203, 362, 532, 1028
SduI GDGCHC 3 cut(s) 607, 1199, 1229
SexAI ACCWGGT 1 cut(s) 1026
SfaNI GCATC 2 cut(s) 1167, 1227
SfuI TTCGAA 1 cut(s) 1153
SinI GGWCC 2 cut(s) 650, 1501
SmlI CTYRAG 1 cut(s) 18
SmoI CTYRAG 1 cut(s) 18
SpeI ACTAGT 1 cut(s) 623
Sse9I AATT 5 cut(s) 883, 1327, 1456, 1466, 1496
SsiI CCGC 3 cut(s) 376, 503, 789
SspMI CTAG 4 cut(s) 624, 1100, 1106, 1214
StyD4I CCNGG 5 cut(s) 171, 201, 360, 530, 1026
StyI CCWWGG 4 cut(s) 852, 1261, 1407, 1509
TaaI ACNGT 5 cut(s) 300, 412, 427, 552, 700
TaiI ACGT 4 cut(s) 57, 258, 351, 1232
TaqI TCGA 8 cut(s) 57, 516, 971, 1071, 1153, 1221, 1254, 1277
TaqII GACCGA 1 cut(s) 359
TasI AATT 5 cut(s) 883, 1327, 1456, 1466, 1496
TatI WGTACW 2 cut(s) 300, 795
TauI GCSGC 1 cut(s) 379
TfiI GAWTC 3 cut(s) 667, 1155, 1432
Tru1I TTAA 1 cut(s) 867
Tru9I TTAA 1 cut(s) 867
TscAI CASTG 5 cut(s) 442, 768, 904, 969, 1302
TseFI GTSAC 4 cut(s) 232, 481, 508, 1315
TseI GCWGC 1 cut(s) 449
Tsp45I GTSAC 4 cut(s) 232, 481, 508, 1315
TspDTI ATGAA 5 cut(s) 335, 629, 735, 1072, 1292
TspGWI ACGGA 3 cut(s) 207, 251, 300
TspRI CASTG 5 cut(s) 442, 768, 904, 969, 1302
VpaK11BI GGWCC 2 cut(s) 650, 1501
XapI RAATTY 2 cut(s) 1456, 1466
XceI RCATGY 1 cut(s) 844
XcmI CCANNNNNNNNNTGG 1 cut(s) 290
XspI CTAG 4 cut(s) 624, 1100, 1106, 1214
ZraI GACGTC 1 cut(s) 256
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.