pycom08g03850

breast cancer carboxy-terminal domain

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
pyrus_communis
Chr8
OG0006642
Physical Location & Seq
Reverse (-)
2930816 .. 2932731
1916 bp
Loading structure...
UTR
Exon/CDS
Intron
pycom08g03850.1

Sequence Viewer

Length: 1197 bp
ATGCGTTTAGATGAGTTGAATAGGTTCGTTGGGTTAATTGGCACGGAAAACACTTGTCTTCCTGTTGGTGTTCGTGGAGCCAAGCAGTTGGACACGATTGAGGAACCACGTTTTTCCTTTCCCGGAAGAGAGTCTACCAGAAATACTGACCCTGGTCACTCTACTCTGTCTGGTCACTCCATGTATGTCGACTTAGACATTTCATCTGAACTGAGGAAAAAGGTTATGGAGGCTGCTAGTAGAGAGGGTGCCACATTTGTAGATCAGTGGTTTGTTGGTTGTGAAGCCAGTCATGTAGTGTGCGAAGGGTCTTCTAGTTGTAAATATCTTGGCCATTCAAGCAATATCGTTACACCACTGTGGGTTTTGAAAACAGCCAAAGAGAAGTATGTGCAACGGCTCGTGCACATGTCTGCGGATTTGGCCAGACAAGTTGGTATGATGCTTGAAGAGTTGCAGAATGGCATTGCTGATGGGGAAACAGATGAAGGAAAAGTCCCTGAAGATGTTAAAGCTTATAGAAATAAAGCAAGCCATGAAAAGAGACAACAGATTGTGAATTCTGCTAAAACTGGGGTCAGAAATCGTCGCGGTCTTCGTATGCAGACTTGCCAAACGCCAATGCGTCCAATAACCCCTAGCAGCCTTTTGGATTCAATCTGCTGGTCAATATCCGAACCAACATCAACGGCTTCAATCTACACCGAAAGTGTCAGTGTTGAAGATGGTAGCGAACATCATGCATCTGTATTCTTTGATGCAAAAGGTGATGGAAAGGATTCCGAAGCTTCATTTGCAAACTTAACCAGGCCGCTCAAGGAAAGTGAGAAATCTGAATTGATATTCAAAAACCATTTTCTTACTATCCTGTTTCCTGTCGACCGATTTGCTGAGATGGGGCCATCTTCTAGAACATTTGTCAGCGATAACGGGTTCACATGCTTGCAGGTGTTGGATCATATCTATGCATTTTATCAGGAGAACATGTCAGCCCTTGAAATAGAGTCTGCAATCCACACCGATTCAAGGCATGCTGATCGGCTTCGATCGGTGTACTCCAGTAAAGAAACAGAAGAACGCGGTTACGCAATTTTTAGGCGGATTGACTTTCTAGGCAGTCGTAAAAGTTTTGAAATGTTGAAGCGCGTCAACGGAGAGAACAGCAGCAATGTGTATGAGCTTTTAATTAGAGCCTAA
Functional Annotation
Gene Ontology
Molecular Function
Biological Process
Cellular Component
No ontology terms assigned.
KEGG Pathways
Metabolic & Signaling
No pathways identified.
Pfam Domains
Protein Families
PTCB-BRCT

Protein Analysis

399

Amino Acids

44.68

Weight (kDa)

6.0

Isoelectric Point (pI)

46.98

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
DUF6699 PF20415 308 - 382 2.2e-07 Family of unknown function (DUF6699)
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
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Publication-ready
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Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AarI CACCTGC 1 cut(s) 937
Acc36I ACCTGC 1 cut(s) 937
AccB1I GGYRCC 1 cut(s) 248
AccBSI CCGCTC 1 cut(s) 814
AccI GTMKAC 3 cut(s) 134, 189, 879
AccII CGCG 3 cut(s) 591, 1080, 1146
AciI CCGC 5 cut(s) 416, 591, 812, 1080, 1099
AclWI GGATC 1 cut(s) 963
AcoI YGGCCR 2 cut(s) 331, 423
AcsI RAATTY 1 cut(s) 559
AcuI CTGAAG 1 cut(s) 522
AfaI GTAC 1 cut(s) 1055
AfiI CCNNNNNNNGG 1 cut(s) 1026
AflIII ACRYGT 2 cut(s) 408, 984
AjnI CCWGG 2 cut(s) 151, 806
AleI CACNNNNGTG 1 cut(s) 358
AluBI AGCT 3 cut(s) 515, 788, 1180
AluI AGCT 3 cut(s) 515, 788, 1180
Alw21I GWGCWC 1 cut(s) 408
Alw26I GTCTC 1 cut(s) 538
Alw44I GTGCAC 1 cut(s) 404
AlwI GGATC 1 cut(s) 963
AoxI GGCC 4 cut(s) 331, 423, 809, 899
ApaLI GTGCAC 1 cut(s) 404
ApeKI GCWGC 3 cut(s) 233, 642, 1164
ApoI RAATTY 1 cut(s) 559
Asp700I GAANNNNTTC 2 cut(s) 23, 778
AspLEI GCGC 1 cut(s) 1146
AspS9I GGNCC 1 cut(s) 899
AsuC2I CCSGG 1 cut(s) 123
AsuHPI GGTGA 1 cut(s) 779
BaeGI GKGCMC 1 cut(s) 408
BalI TGGCCA 2 cut(s) 333, 425
BanI GGYRCC 1 cut(s) 248
BarI GAAGNNNNNNTAC 2 cut(s) 118, 150
BauI CACGAG 1 cut(s) 401
BbsI GAAGAC 3 cut(s) 50, 303, 587
Bbv12I GWGCWC 1 cut(s) 408
BbvI GCAGC 3 cut(s) 220, 654, 1176
BccI CCATC 5 cut(s) 467, 719, 764, 889, 910
BceAI ACGGC 2 cut(s) 413, 705
BcgI CGANNNNNNTGC 6 cut(s) 722, 756, 869, 903, 1019, 1053
BciT130I CCWGG 2 cut(s) 153, 808
BcnI CCSGG 1 cut(s) 123
BcoDI GTCTC 1 cut(s) 538
BfaI CTAG 5 cut(s) 237, 315, 639, 909, 1112
BfuAI ACCTGC 1 cut(s) 937
BisI GCNGC 4 cut(s) 234, 643, 812, 1165
BlsI GCNGC 4 cut(s) 235, 644, 813, 1166
Bme1390I CCNGG 3 cut(s) 123, 153, 808
BmgT120I GGNCC 1 cut(s) 899
BmiI GGNNCC 4 cut(s) 79, 105, 250, 900
BmrFI CCNGG 3 cut(s) 123, 153, 808
BmrI ACTGGG 1 cut(s) 582
BmsI GCATC 3 cut(s) 432, 748, 752
BmuI ACTGGG 1 cut(s) 582
BoxI GACNNNNGTC 1 cut(s) 153
BpiI GAAGAC 3 cut(s) 50, 303, 587
BpmI CTGGAG 1 cut(s) 1042
BpuEI CTTGAG 1 cut(s) 800
BpuMI CCSGG 1 cut(s) 123
BsaJI CCNNGG 1 cut(s) 151
BsaXI ACNNNNNCTCC 2 cut(s) 971, 1001
Bsc4I CCNNNNNNNGG 1 cut(s) 1026
Bse1I ACTGG 3 cut(s) 288, 577, 1059
Bse3DI GCAATG 2 cut(s) 465, 1174
BseBI CCWGG 2 cut(s) 153, 808
BseDI CCNNGG 1 cut(s) 151
BseLI CCNNNNNNNGG 1 cut(s) 1026
BseMI GCAATG 2 cut(s) 465, 1174
BseMII CTCAG 2 cut(s) 203, 882
BseNI ACTGG 3 cut(s) 288, 577, 1059
BseSI GKGCMC 1 cut(s) 408
BseXI GCAGC 3 cut(s) 220, 654, 1176
Bsh1236I CGCG 3 cut(s) 591, 1080, 1146
Bsh1285I CGRYCG 2 cut(s) 883, 1049
BshFI GGCC 4 cut(s) 333, 425, 811, 901
BshNI GGYRCC 1 cut(s) 248
BsiEI CGRYCG 2 cut(s) 883, 1049
BsiHKAI GWGCWC 1 cut(s) 408
BsiSI CCGG 1 cut(s) 123
BslFI GGGAC 1 cut(s) 482
BslI CCNNNNNNNGG 1 cut(s) 1026
BsmAI GTCTC 1 cut(s) 538
BsmFI GGGAC 1 cut(s) 482
BsnI GGCC 4 cut(s) 333, 425, 811, 901
Bsp1286I GDGCHC 1 cut(s) 408
Bsp143I GATC 4 cut(s) 262, 955, 1036, 1046
BspACI CCGC 5 cut(s) 416, 591, 812, 1080, 1099
BspANI GGCC 4 cut(s) 333, 425, 811, 901
BspCNI CTCAG 2 cut(s) 204, 883
BspFNI CGCG 3 cut(s) 591, 1080, 1146
BspLI GGNNCC 4 cut(s) 79, 105, 250, 900
BspMI ACCTGC 1 cut(s) 937
BspPI GGATC 1 cut(s) 963
BspT107I GGYRCC 1 cut(s) 248
BsrBI CCGCTC 1 cut(s) 814
BsrDI GCAATG 2 cut(s) 465, 1174
BsrI ACTGG 3 cut(s) 288, 577, 1059
BssECI CCNNGG 1 cut(s) 151
BssMI GATC 4 cut(s) 262, 955, 1036, 1046
BssSI CACGAG 1 cut(s) 401
Bst2BI CACGAG 1 cut(s) 401
Bst2UI CCWGG 2 cut(s) 153, 808
Bst4CI ACNGT 1 cut(s) 360
Bst6I CTCTTC 2 cut(s) 121, 444
BstC8I GCNNGC 3 cut(s) 532, 944, 1032
BstDEI CTNAG 3 cut(s) 193, 212, 891
BstFNI CGCG 3 cut(s) 591, 1080, 1146
BstHHI GCGC 1 cut(s) 1146
BstKTI GATC 4 cut(s) 265, 958, 1039, 1049
BstMAI GTCTC 1 cut(s) 538
BstMBI GATC 4 cut(s) 262, 955, 1036, 1046
BstMCI CGRYCG 2 cut(s) 883, 1049
BstMWI GCNNNNNNNGC 3 cut(s) 339, 422, 794
BstNI CCWGG 2 cut(s) 153, 808
BstNSI RCATGY 4 cut(s) 412, 942, 988, 1034
BstPAI GACNNNNGTC 1 cut(s) 153
BstSCI CCNGG 3 cut(s) 121, 151, 806
BstSLI GKGCMC 1 cut(s) 408
BstUI CGCG 3 cut(s) 591, 1080, 1146
BstV1I GCAGC 3 cut(s) 220, 654, 1176
BstV2I GAAGAC 3 cut(s) 50, 303, 587
BstXI CCANNNNNNTGG 1 cut(s) 88
BsuRI GGCC 4 cut(s) 333, 425, 811, 901
BtsIMutI CAGTG 3 cut(s) 272, 356, 721
BveI ACCTGC 1 cut(s) 937
Cac8I GCNNGC 3 cut(s) 532, 944, 1032
CfoI GCGC 1 cut(s) 1146
Cfr13I GGNCC 1 cut(s) 899
CseI GACGC 2 cut(s) 614, 1135
Csp6I GTAC 1 cut(s) 1054
CviAII CATG 8 cut(s) 181, 293, 409, 536, 740, 939, 985, 1031
CviQI GTAC 1 cut(s) 1054
DdeI CTNAG 3 cut(s) 193, 212, 891
DpnI GATC 4 cut(s) 264, 957, 1038, 1048
DpnII GATC 4 cut(s) 262, 955, 1036, 1046
EaeI YGGCCR 2 cut(s) 331, 423
Eam1104I CTCTTC 2 cut(s) 121, 444
EarI CTCTTC 2 cut(s) 121, 444
EciI GGCGGA 1 cut(s) 1114
Eco57I CTGAAG 1 cut(s) 522
EcoRI GAATTC 1 cut(s) 559
EcoRII CCWGG 2 cut(s) 151, 806
EcoT22I ATGCAT 2 cut(s) 745, 970
FaeI CATG 8 cut(s) 184, 296, 412, 539, 743, 942, 988, 1034
FaqI GGGAC 1 cut(s) 482
FatI CATG 8 cut(s) 180, 292, 408, 535, 739, 938, 984, 1030
FblI GTMKAC 3 cut(s) 134, 189, 879
Fnu4HI GCNGC 4 cut(s) 234, 643, 812, 1165
Fsp4HI GCNGC 4 cut(s) 234, 643, 812, 1165
FspBI CTAG 5 cut(s) 237, 315, 639, 909, 1112
GlaI GCGC 1 cut(s) 1145
GluI GCNGC 4 cut(s) 234, 643, 812, 1165
GsuI CTGGAG 1 cut(s) 1042
HaeIII GGCC 4 cut(s) 333, 425, 811, 901
HapII CCGG 1 cut(s) 123
HgaI GACGC 2 cut(s) 614, 1135
HhaI GCGC 1 cut(s) 1146
Hin1II CATG 8 cut(s) 184, 296, 412, 539, 743, 942, 988, 1034
Hin6I GCGC 1 cut(s) 1144
HinP1I GCGC 1 cut(s) 1144
HincII GTYRAC 3 cut(s) 190, 880, 1150
HindII GTYRAC 3 cut(s) 190, 880, 1150
HindIII AAGCTT 2 cut(s) 513, 786
HinfI GANTC 5 cut(s) 131, 653, 779, 1004, 1022
HpaII CCGG 1 cut(s) 123
HphI GGTGA 1 cut(s) 779
Hpy166II GTNNAC 7 cut(s) 135, 190, 406, 880, 936, 1054, 1150
Hpy188I TCNGA 5 cut(s) 208, 581, 676, 784, 835
Hpy188III TCNNGA 2 cut(s) 909, 977
Hpy8I GTNNAC 7 cut(s) 135, 190, 406, 880, 936, 1054, 1150
Hpy99I CGWCG 1 cut(s) 591
HpyAV CCTTC 2 cut(s) 299, 482
HpyCH4III ACNGT 1 cut(s) 360
HpyCH4IV ACGT 1 cut(s) 109
HpyF10VI GCNNNNNNNGC 3 cut(s) 339, 422, 794
HpyF3I CTNAG 3 cut(s) 193, 212, 891
HpySE526I ACGT 1 cut(s) 109
Hsp92II CATG 8 cut(s) 184, 296, 412, 539, 743, 942, 988, 1034
HspAI GCGC 1 cut(s) 1144
Kzo9I GATC 4 cut(s) 262, 955, 1036, 1046
LmnI GCTCC 1 cut(s) 77
Lsp1109I GCAGC 3 cut(s) 220, 654, 1176
LweI GCATC 3 cut(s) 432, 748, 752
MaeI CTAG 5 cut(s) 237, 315, 639, 909, 1112
MaeII ACGT 1 cut(s) 109
MaeIII GTNAC 4 cut(s) 155, 173, 349, 1082
MalI GATC 4 cut(s) 264, 957, 1038, 1048
MbiI CCGCTC 1 cut(s) 814
MboI GATC 4 cut(s) 262, 955, 1036, 1046
MboII GAAGA 9 cut(s) 50, 138, 303, 461, 515, 587, 734, 897, 1085
MhlI GDGCHC 1 cut(s) 408
MlsI TGGCCA 2 cut(s) 333, 425
MluCI AATT 5 cut(s) 36, 559, 836, 1089, 1185
MluNI TGGCCA 2 cut(s) 333, 425
MlyI GAGTC 2 cut(s) 140, 1013
MmeI TCCRAC 2 cut(s) 69, 933
MnlI CCTC 4 cut(s) 94, 207, 223, 238
Mox20I TGGCCA 2 cut(s) 333, 425
Mph1103I ATGCAT 2 cut(s) 745, 970
MroXI GAANNNNTTC 2 cut(s) 23, 778
MscI TGGCCA 2 cut(s) 333, 425
MseI TTAA 4 cut(s) 35, 510, 803, 1184
MslI CAYNNNNRTG 2 cut(s) 358, 963
Msp20I TGGCCA 2 cut(s) 333, 425
MspI CCGG 1 cut(s) 123
MspR9I CCNGG 3 cut(s) 123, 153, 808
MvaI CCWGG 2 cut(s) 153, 808
MvnI CGCG 3 cut(s) 591, 1080, 1146
MwoI GCNNNNNNNGC 3 cut(s) 339, 422, 794
NciI CCSGG 1 cut(s) 123
NdeII GATC 4 cut(s) 262, 955, 1036, 1046
NlaIII CATG 8 cut(s) 184, 296, 412, 539, 743, 942, 988, 1034
NlaIV GGNNCC 4 cut(s) 79, 105, 250, 900
NmuCI GTSAC 2 cut(s) 155, 173
NsiI ATGCAT 2 cut(s) 745, 970
NspI RCATGY 4 cut(s) 412, 942, 988, 1034
OliI CACNNNNGTG 1 cut(s) 358
PaeI GCATGC 1 cut(s) 1034
PaqCI CACCTGC 1 cut(s) 937
PciI ACATGT 2 cut(s) 408, 984
PcsI WCGNNNNNNNCGW 1 cut(s) 595
PdmI GAANNNNTTC 2 cut(s) 23, 778
PfeI GAWTC 3 cut(s) 653, 779, 1022
PfoI TCCNGGA 1 cut(s) 121
PkrI GCNGC 4 cut(s) 235, 644, 813, 1166
Ple19I CGATCG 1 cut(s) 1049
PleI GAGTC 2 cut(s) 139, 1012
PpsI GAGTC 2 cut(s) 139, 1012
PscI ACATGT 2 cut(s) 408, 984
PshAI GACNNNNGTC 1 cut(s) 153
Psp6I CCWGG 2 cut(s) 151, 806
PspGI CCWGG 2 cut(s) 151, 806
PspN4I GGNNCC 4 cut(s) 79, 105, 250, 900
PspPI GGNCC 1 cut(s) 899
PvuI CGATCG 1 cut(s) 1049
RsaI GTAC 1 cut(s) 1055
RsaNI GTAC 1 cut(s) 1054
RseI CAYNNNNRTG 2 cut(s) 358, 963
SalI GTCGAC 2 cut(s) 188, 878
SaqAI TTAA 4 cut(s) 35, 510, 803, 1184
SatI GCNGC 4 cut(s) 234, 643, 812, 1165
Sau3AI GATC 4 cut(s) 262, 955, 1036, 1046
Sau96I GGNCC 1 cut(s) 899
SchI GAGTC 2 cut(s) 140, 1013
ScrFI CCNGG 3 cut(s) 123, 153, 808
SduI GDGCHC 1 cut(s) 408
SetI ASST 8 cut(s) 26, 112, 225, 517, 769, 790, 951, 1182
SfaNI GCATC 3 cut(s) 432, 748, 752
SmiMI CAYNNNNRTG 2 cut(s) 358, 963
SmlI CTYRAG 1 cut(s) 815
SmoI CTYRAG 1 cut(s) 815
SphI GCATGC 1 cut(s) 1034
Sse9I AATT 5 cut(s) 36, 559, 836, 1089, 1185
SsiI CCGC 5 cut(s) 416, 591, 812, 1080, 1099
SspMI CTAG 5 cut(s) 237, 315, 639, 909, 1112
StyD4I CCNGG 3 cut(s) 121, 151, 806
TaaI ACNGT 1 cut(s) 360
TaiI ACGT 1 cut(s) 112
TaqI TCGA 3 cut(s) 189, 879, 1045
TaqII GACCGA 1 cut(s) 897
TasI AATT 5 cut(s) 36, 559, 836, 1089, 1185
TatI WGTACW 1 cut(s) 1053
TauI GCSGC 1 cut(s) 814
TfiI GAWTC 3 cut(s) 653, 779, 1022
Tru1I TTAA 4 cut(s) 35, 510, 803, 1184
Tru9I TTAA 4 cut(s) 35, 510, 803, 1184
TscAI CASTG 3 cut(s) 272, 363, 721
TseFI GTSAC 2 cut(s) 155, 173
TseI GCWGC 3 cut(s) 233, 642, 1164
Tsp45I GTSAC 2 cut(s) 155, 173
TspDTI ATGAA 4 cut(s) 192, 501, 552, 780
TspGWI ACGGA 2 cut(s) 59, 1167
TspRI CASTG 3 cut(s) 272, 363, 721
VneI GTGCAC 1 cut(s) 404
XapI RAATTY 1 cut(s) 559
XbaI TCTAGA 1 cut(s) 908
XceI RCATGY 4 cut(s) 412, 942, 988, 1034
XmiI GTMKAC 3 cut(s) 134, 189, 879
XmnI GAANNNNTTC 2 cut(s) 23, 778
XspI CTAG 5 cut(s) 237, 315, 639, 909, 1112
Zsp2I ATGCAT 2 cut(s) 745, 970
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.