Basic Information

Type: gene

Biological Identity

Species

rosa_wichuraiana

Chromosome

Chr4

Orthogroup ID

OG0018597

Physical Location & Seq

Genomic Coordinates Reverse (-)

49987659 .. 49988780

Gene Structure 1122 bp

Loading structure...

UTR

Exon/CDS

Intron

Transcript / Protein ID

Rw4G024110.1

Sequence Viewer

CDS Protein Promoter (2k)

Length: 1122 bp

ATGGCATCGTCTCTCTCATTCAAACAAGTTCTGGGCCCTTCAGTCCCTGAAGGGCTTTCTGGGTTGTGCTCTTGTCAGTCTGATCTTCGAAACCTGTCGTCCCCCTCCGTACAATTCTTGGCCCGCCCTCGAACCTTCAAGAAACTCAAAGTGCTGGCTGCTGGGACTACTTCAGGAAACTACTTTCGGGTTACAACTTATGGAGAGTTTCGTCGTGCTGGTGTTAGTTTTGTAATGGATGGAGTTCCTCCTCGGAGTCAACTATCTGAAGCTGATTTGCAAGCGGGCCTCGACAGAATAAGGAGGCCAGGTCAGATCAGCCCACTTATCAAAACTGACACATGCAAGATACTCTCGGGAGTCCATGAAGGATTGACTATTGGGACACCAATTCATGTGTTTATACCCAATCCTGATCAGACAGGTCGATGTGGTTATGATGAAATCTCCGTAGCTTACAGGCCTTCACATGCAGATCTAACACGCGACCTGAAGTATGGTATCAGATCCATACTTAAGGGTGGTGGTATATTTTCAGCTAGGGAAACAATAGGAAGAGTTGCTGCAGGAGCAGCTGCGAAGAAAATCCTCAAGGACTTGGCCGGAATCGAGGTTCTTGGTTATGTTTCACAAGTTCACAAGGTTGTCCTCCCGGAGGACTTGGTTGATCATGACACCCTGACACTTGATCAGATAGAGAGCAATAGAGTTAGGTGTCCAGATCATGAATACGCAGAGAAGATGATAGCTGCCATCCATGCTGTTAGGGTTAGAGGGGAGGATCAACCTATTGGTGGTGTTGTGAGGTGCATAGTTAGGAATTGCCCGCGGGGTCTTCTTGGTTCGCCTTTCTTTGACAAACTTGGAGCTGAATTTGCTAAAGCTTGTCTGTCATTACCTGCAACAAAGGGATTTGAATTCGGAAGGGGCCTTGCAGCAGGTACCTTAAACATGAAGATAGCTTTCAAGCCAACAGCTACAAATGCAAGGAACCAGAATGCAGTGAGTACAGATAAGGAGAGTGAACTAACGGATACTTGTGTTGTCCCCCGAGCGGTTCCAATGGTGGAGGCTCAAGTGCCGCTGGTGCTCATGGATGAATTAATGACTCAATATGCCTAA

Functional Annotation

Gene Ontology

Molecular Function
Biological Process
Cellular Component

GO:0000166 GO:0003674 GO:0003824 GO:0004107 GO:0005488 GO:0005575 GO:0005622 GO:0005623 GO:0005634 GO:0005730 GO:0005737 GO:0005829 GO:0006082 GO:0006520 GO:0006725 GO:0006807 GO:0008150 GO:0008152 GO:0008652 GO:0009058 GO:0009072 GO:0009073 GO:0009423 GO:0009507 GO:0009532 GO:0009536 GO:0009570 GO:0009987 GO:0010181 GO:0016053 GO:0016829 GO:0016835 GO:0016838 GO:0019438 GO:0019752 GO:0031974 GO:0031981 GO:0032553 GO:0036094 GO:0043167 GO:0043168 GO:0043226 GO:0043227 GO:0043228 GO:0043229 GO:0043231 GO:0043232 GO:0043233 GO:0043436 GO:0043648 GO:0043650 GO:0044237 GO:0044238 GO:0044249 GO:0044281 GO:0044283 GO:0044422 GO:0044424 GO:0044428 GO:0044434 GO:0044435 GO:0044444 GO:0044446 GO:0044464 GO:0046394 GO:0046417 GO:0048037 GO:0050662 GO:0070013 GO:0071704 GO:0097159 GO:0097367 GO:1901265 GO:1901360 GO:1901362 GO:1901363 GO:1901564 GO:1901566 GO:1901576

KEGG Pathways

Metabolic & Signaling

ko00400 ko01100 ko01110 ko01130 ko01230 map00400 map01100 map01110 map01130 map01230

Pfam Domains

Protein Families

Chorismate_synt

Protein Analysis

373

Amino Acids

40.27

Weight (kDa)

8.9

Isoelectric Point (pI)

35.63

Instability Index

Protein Domains (Pfam)

Domain Name	Pfam ID	Position	E-value	Description
Chorismate_synt	PF01264	62 - 313	1.2e-67	Chorismate synthase
Chorismate_synt	PF01264	316 - 369	5.6e-07	Chorismate synthase

Hydrophobicity Profile (Kyte-Doolittle)

AI Structure Prediction Report

Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter

Style Settings

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Align Labels (Cladogram)

Image

Tree File

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Publication-ready

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Orthologous Genes (Group: OG0018597)

Species	Orthologous Gene IDs
rosa_chinensis	RchiOBHm_Chr4g0427911
rosa_laevigata	RLG00000007201
rosa_multiflora	Rmu_sc0000066.1_g000014 Rmu_sc0009221.1_g000002
rosa_rugosa	Rorug04G0220500
rosa_samantha	Rh4AG277500 Rh4BG283300 Rh4CG298800 Rh4DG280400
rosa_wichuraiana	Rw4G024110

Restriction Enzyme Sites

1 / 10

Enzyme	Recognition Site	Cut Count	Positions (bp)
Acc36I	ACCTGC	2 cut(s)	907, 929
Acc65I	GGTACC	1 cut(s)	941
AccB1I	GGYRCC	1 cut(s)	941
AccBSI	CCGCTC	1 cut(s)	1055
AccII	CGCG	2 cut(s)	486, 829
AciI	CCGC	6 cut(s)	124, 284, 827, 829, 1055, 1082
AclWI	GGATC	2 cut(s)	501, 789
AcoI	YGGCCR	1 cut(s)	600
AcsI	RAATTY	2 cut(s)	872, 917
AcuI	CTGAAG	5 cut(s)	24, 69, 156, 288, 512
AfaI	GTAC	3 cut(s)	111, 943, 1009
AfiI	CCNNNNNNNGG	3 cut(s)	655, 794, 1054
AflII	CTTAAG	1 cut(s)	515
AgsI	TTSAA	4 cut(s)	22, 139, 917, 967
AjnI	CCWGG	1 cut(s)	307
AloI	GAACNNNNNNTCC	2 cut(s)	597, 629
AluBI	AGCT	9 cut(s)	272, 455, 539, 575, 749, 869, 884, 962, 977
AluI	AGCT	9 cut(s)	272, 455, 539, 575, 749, 869, 884, 962, 977
Alw21I	GWGCWC	2 cut(s)	71, 1092
Alw26I	GTCTC	1 cut(s)	15
AlwI	GGATC	2 cut(s)	501, 789
AlwNI	CAGNNNCTG	1 cut(s)	47
Ama87I	CYCGRG	2 cut(s)	355, 1050
AoxI	GGCC	7 cut(s)	34, 120, 286, 305, 461, 600, 928
ApaI	GGGCCC	1 cut(s)	38
ApeKI	GCWGC	6 cut(s)	158, 563, 572, 575, 749, 935
ApoI	RAATTY	2 cut(s)	872, 917
AseI	ATTAAT	1 cut(s)	1103
Asp718I	GGTACC	1 cut(s)	941
AspS9I	GGNCC	5 cut(s)	34, 35, 121, 286, 928
AsuC2I	CCSGG	1 cut(s)	653
AsuII	TTCGAA	1 cut(s)	88
AvaI	CYCGRG	2 cut(s)	355, 1050
BaeGI	GKGCMC	1 cut(s)	38
BaeI	ACNNNNGTAYC	2 cut(s)	1026, 1059
BanI	GGYRCC	1 cut(s)	941
BanII	GRGCYC	1 cut(s)	38
BbsI	GAAGAC	1 cut(s)	827
Bbv12I	GWGCWC	2 cut(s)	71, 1092
BbvI	GCAGC	6 cut(s)	145, 550, 562, 584, 736, 947
BccI	CCATC	2 cut(s)	233, 761
BciT130I	CCWGG	1 cut(s)	309
BciVI	GTATCC	1 cut(s)	1027
BclI	TGATCA	3 cut(s)	415, 667, 688
BcnI	CCSGG	1 cut(s)	653
BcoDI	GTCTC	1 cut(s)	15
BfaI	CTAG	1 cut(s)	540
BfmI	CTRYAG	1 cut(s)	564
BfrI	CTTAAG	1 cut(s)	515
BfuAI	ACCTGC	2 cut(s)	907, 929
BfuI	GTATCC	1 cut(s)	1027
BglII	AGATCT	1 cut(s)	475
BisI	GCNGC	7 cut(s)	159, 564, 573, 576, 750, 936, 1082
BlsI	GCNGC	7 cut(s)	160, 565, 574, 577, 751, 937, 1083
Bme1390I	CCNGG	2 cut(s)	309, 653
BmeT110I	CYCGRG	2 cut(s)	355, 1050
BmgT120I	GGNCC	5 cut(s)	34, 35, 121, 286, 928
BmiI	GGNNCC	5 cut(s)	36, 929, 943, 992, 1059
BmrFI	CCNGG	2 cut(s)	309, 653
BmsI	GCATC	1 cut(s)	14
BpiI	GAAGAC	1 cut(s)	827
Bpu14I	TTCGAA	1 cut(s)	88
BpuEI	CTTGAG	2 cut(s)	575, 1059
BpuMI	CCSGG	1 cut(s)	653
BsaJI	CCNNGG	2 cut(s)	251, 827
BsaXI	ACNNNNNCTCC	2 cut(s)	295, 325
Bsc4I	CCNNNNNNNGG	3 cut(s)	655, 794, 1054
BseBI	CCWGG	1 cut(s)	309
BseDI	CCNNGG	2 cut(s)	251, 827
BseGI	GGATG	3 cut(s)	244, 753, 1102
BseLI	CCNNNNNNNGG	3 cut(s)	655, 794, 1054
BseRI	GAGGAG	1 cut(s)	240
BseSI	GKGCMC	1 cut(s)	38
BseXI	GCAGC	6 cut(s)	145, 550, 562, 584, 736, 947
BseYI	CCCAGC	1 cut(s)	161
Bsh1236I	CGCG	2 cut(s)	486, 829
BshFI	GGCC	7 cut(s)	36, 122, 288, 307, 463, 602, 930
BshNI	GGYRCC	1 cut(s)	941
BsiHKAI	GWGCWC	2 cut(s)	71, 1092
BsiHKCI	CYCGRG	2 cut(s)	355, 1050
BsiSI	CCGG	2 cut(s)	603, 653
BslFI	GGGAC	5 cut(s)	29, 85, 178, 397, 1031
BslI	CCNNNNNNNGG	3 cut(s)	655, 794, 1054
BsmAI	GTCTC	1 cut(s)	15
BsmBI	CGTCTC	1 cut(s)	15
BsmFI	GGGAC	5 cut(s)	29, 85, 178, 397, 1031
BsmI	GAATGC	1 cut(s)	1003
BsnI	GGCC	7 cut(s)	36, 122, 288, 307, 463, 602, 930
BsoBI	CYCGRG	2 cut(s)	355, 1050
Bsp119I	TTCGAA	1 cut(s)	88
Bsp120I	GGGCCC	1 cut(s)	34
Bsp1286I	GDGCHC	3 cut(s)	38, 71, 1092
Bsp143I	GATC	9 cut(s)	82, 315, 415, 475, 506, 667, 688, 721, 781
BspACI	CCGC	6 cut(s)	124, 284, 827, 829, 1055, 1082
BspANI	GGCC	7 cut(s)	36, 122, 288, 307, 463, 602, 930
BspFNI	CGCG	2 cut(s)	486, 829
BspHI	TCATGA	2 cut(s)	670, 724
BspLI	GGNNCC	5 cut(s)	36, 929, 943, 992, 1059
BspMAI	CTGCAG	1 cut(s)	568
BspMI	ACCTGC	2 cut(s)	907, 929
BspPI	GGATC	2 cut(s)	501, 789
BspT104I	TTCGAA	1 cut(s)	88
BspT107I	GGYRCC	1 cut(s)	941
BspTI	CTTAAG	1 cut(s)	515
BsrBI	CCGCTC	1 cut(s)	1055
BssECI	CCNNGG	2 cut(s)	251, 827
BssMI	GATC	9 cut(s)	82, 315, 415, 475, 506, 667, 688, 721, 781
Bst2UI	CCWGG	1 cut(s)	309
Bst6I	CTCTTC	1 cut(s)	550
BstAFI	CTTAAG	1 cut(s)	515
BstBI	TTCGAA	1 cut(s)	88
BstC8I	GCNNGC	5 cut(s)	124, 156, 282, 286, 827
BstDSI	CCRYGG	1 cut(s)	827
BstENI	CCTNNNNNAGG	1 cut(s)	653
BstF5I	GGATG	3 cut(s)	244, 753, 1102
BstFNI	CGCG	2 cut(s)	486, 829
BstKTI	GATC	9 cut(s)	85, 318, 418, 478, 509, 670, 691, 724, 784
BstMAI	GTCTC	1 cut(s)	15
BstMBI	GATC	9 cut(s)	82, 315, 415, 475, 506, 667, 688, 721, 781
BstMWI	GCNNNNNNNGC	6 cut(s)	569, 572, 758, 875, 983, 1087
BstNI	CCWGG	1 cut(s)	309
BstNSI	RCATGY	2 cut(s)	345, 473
BstSCI	CCNGG	2 cut(s)	307, 651
BstSFI	CTRYAG	1 cut(s)	564
BstSLI	GKGCMC	1 cut(s)	38
BstUI	CGCG	2 cut(s)	486, 829
BstV1I	GCAGC	6 cut(s)	145, 550, 562, 584, 736, 947
BstV2I	GAAGAC	1 cut(s)	827
BstX2I	RGATCY	2 cut(s)	475, 506
BstYI	RGATCY	2 cut(s)	475, 506
BsuI	GTATCC	1 cut(s)	1027
BsuRI	GGCC	7 cut(s)	36, 122, 288, 307, 463, 602, 930
BtgI	CCRYGG	1 cut(s)	827
BtsCI	GGATG	3 cut(s)	244, 753, 1102
BtsI	GCAGTG	1 cut(s)	1008
BtsIMutI	CAGTG	1 cut(s)	1008
BveI	ACCTGC	2 cut(s)	907, 929
Cac8I	GCNNGC	5 cut(s)	124, 156, 282, 286, 827
CaiI	CAGNNNCTG	1 cut(s)	47
CciI	TCATGA	2 cut(s)	670, 724
Cfr13I	GGNCC	5 cut(s)	34, 35, 121, 286, 928
Cfr42I	CCGCGG	1 cut(s)	830
Csp6I	GTAC	3 cut(s)	110, 942, 1008
CviAII	CATG	9 cut(s)	342, 365, 395, 470, 671, 725, 758, 952, 1093
CviQI	GTAC	3 cut(s)	110, 942, 1008
DpnI	GATC	9 cut(s)	84, 317, 417, 477, 508, 669, 690, 723, 783
DpnII	GATC	9 cut(s)	82, 315, 415, 475, 506, 667, 688, 721, 781
EaeI	YGGCCR	1 cut(s)	600
Eam1104I	CTCTTC	1 cut(s)	550
EarI	CTCTTC	1 cut(s)	550
Eco147I	AGGCCT	1 cut(s)	463
Eco24I	GRGCYC	1 cut(s)	38
Eco57I	CTGAAG	5 cut(s)	24, 69, 156, 288, 512
Eco88I	CYCGRG	2 cut(s)	355, 1050
EcoNI	CCTNNNNNAGG	1 cut(s)	653
EcoO109I	RGGNCCY	2 cut(s)	35, 928
EcoRI	GAATTC	1 cut(s)	917
EcoRII	CCWGG	1 cut(s)	307
EcoT38I	GRGCYC	1 cut(s)	38
Esp3I	CGTCTC	1 cut(s)	15
FaeI	CATG	9 cut(s)	345, 368, 398, 473, 674, 728, 761, 955, 1096
FaqI	GGGAC	5 cut(s)	29, 85, 178, 397, 1031
FatI	CATG	9 cut(s)	341, 364, 394, 469, 670, 724, 757, 951, 1092
FauI	CCCGC	4 cut(s)	131, 277, 822, 834
FbaI	TGATCA	3 cut(s)	415, 667, 688
Fnu4HI	GCNGC	7 cut(s)	159, 564, 573, 576, 750, 936, 1082
FokI	GGATG	3 cut(s)	251, 740, 1109
FriOI	GRGCYC	1 cut(s)	38
Fsp4HI	GCNGC	7 cut(s)	159, 564, 573, 576, 750, 936, 1082
FspBI	CTAG	1 cut(s)	540
GluI	GCNGC	7 cut(s)	159, 564, 573, 576, 750, 936, 1082
GsaI	CCCAGC	1 cut(s)	165
HaeIII	GGCC	7 cut(s)	36, 122, 288, 307, 463, 602, 930
HapII	CCGG	2 cut(s)	603, 653
Hin1II	CATG	9 cut(s)	345, 368, 398, 473, 674, 728, 761, 955, 1096
HincII	GTYRAC	1 cut(s)	260
HindII	GTYRAC	1 cut(s)	260
HindIII	AAGCTT	1 cut(s)	882
HinfI	GANTC	4 cut(s)	256, 360, 606, 1108
HpaII	CCGG	2 cut(s)	603, 653
Hpy166II	GTNNAC	3 cut(s)	260, 637, 1025
Hpy188I	TCNGA	8 cut(s)	82, 255, 268, 315, 420, 506, 693, 923
Hpy188III	TCNNGA	7 cut(s)	139, 174, 357, 413, 671, 719, 725
Hpy8I	GTNNAC	3 cut(s)	260, 637, 1025
Hpy99I	CGWCG	1 cut(s)	216
HpyAV	CCTTC	6 cut(s)	44, 48, 145, 362, 474, 918
HpyCH4V	TGCA	9 cut(s)	280, 345, 473, 566, 810, 902, 935, 986, 1001
HpyF10VI	GCNNNNNNNGC	6 cut(s)	569, 572, 758, 875, 983, 1087
Hsp92II	CATG	9 cut(s)	345, 368, 398, 473, 674, 728, 761, 955, 1096
KpnI	GGTACC	1 cut(s)	945
Ksp22I	TGATCA	3 cut(s)	415, 667, 688
KspI	CCGCGG	1 cut(s)	830
Kzo9I	GATC	9 cut(s)	82, 315, 415, 475, 506, 667, 688, 721, 781
LmnI	GCTCC	2 cut(s)	569, 866
Lsp1109I	GCAGC	6 cut(s)	145, 550, 562, 584, 736, 947
LweI	GCATC	1 cut(s)	14
MaeI	CTAG	1 cut(s)	540
MaeIII	GTNAC	1 cut(s)	190
MalI	GATC	9 cut(s)	84, 317, 417, 477, 508, 669, 690, 723, 783
MbiI	CCGCTC	1 cut(s)	1055
MboI	GATC	9 cut(s)	82, 315, 415, 475, 506, 667, 688, 721, 781
MboII	GAAGA	6 cut(s)	77, 567, 592, 751, 827, 967
MflI	RGATCY	2 cut(s)	475, 506
MhlI	GDGCHC	3 cut(s)	38, 71, 1092
MluCI	AATT	6 cut(s)	113, 390, 820, 872, 917, 1100
MlyI	GAGTC	3 cut(s)	265, 369, 1102
MseI	TTAA	3 cut(s)	516, 947, 1103
MspA1I	CMGCKG	3 cut(s)	575, 829, 1084
MspCI	CTTAAG	1 cut(s)	515
MspI	CCGG	2 cut(s)	603, 653
MspR9I	CCNGG	2 cut(s)	309, 653
Mva1269I	GAATGC	1 cut(s)	1003
MvaI	CCWGG	1 cut(s)	309
MvnI	CGCG	2 cut(s)	486, 829
MwoI	GCNNNNNNNGC	6 cut(s)	569, 572, 758, 875, 983, 1087
NciI	CCSGG	1 cut(s)	653
NdeII	GATC	9 cut(s)	82, 315, 415, 475, 506, 667, 688, 721, 781
NlaIII	CATG	9 cut(s)	345, 368, 398, 473, 674, 728, 761, 955, 1096
NlaIV	GGNNCC	5 cut(s)	36, 929, 943, 992, 1059
NspI	RCATGY	2 cut(s)	345, 473
NspV	TTCGAA	1 cut(s)	88
PagI	TCATGA	2 cut(s)	670, 724
PceI	AGGCCT	1 cut(s)	463
PctI	GAATGC	1 cut(s)	1003
PfeI	GAWTC	1 cut(s)	606
PfoI	TCCNGGA	1 cut(s)	651
PkrI	GCNGC	7 cut(s)	160, 565, 574, 577, 751, 937, 1083
PleI	GAGTC	3 cut(s)	264, 368, 1102
PpsI	GAGTC	3 cut(s)	264, 368, 1102
PshBI	ATTAAT	1 cut(s)	1103
Psp6I	CCWGG	1 cut(s)	307
PspFI	CCCAGC	1 cut(s)	161
PspGI	CCWGG	1 cut(s)	307
PspN4I	GGNNCC	5 cut(s)	36, 929, 943, 992, 1059
PspOMI	GGGCCC	1 cut(s)	34
PspPI	GGNCC	5 cut(s)	34, 35, 121, 286, 928
PstI	CTGCAG	1 cut(s)	568
PstNI	CAGNNNCTG	1 cut(s)	47
PsuI	RGATCY	2 cut(s)	475, 506
PvuII	CAGCTG	1 cut(s)	575
RsaI	GTAC	3 cut(s)	111, 943, 1009
RsaNI	GTAC	3 cut(s)	110, 942, 1008
SacII	CCGCGG	1 cut(s)	830
SaqAI	TTAA	3 cut(s)	516, 947, 1103
SatI	GCNGC	7 cut(s)	159, 564, 573, 576, 750, 936, 1082
Sau3AI	GATC	9 cut(s)	82, 315, 415, 475, 506, 667, 688, 721, 781
Sau96I	GGNCC	5 cut(s)	34, 35, 121, 286, 928
SchI	GAGTC	3 cut(s)	265, 369, 1102
ScrFI	CCNGG	2 cut(s)	309, 653
SduI	GDGCHC	3 cut(s)	38, 71, 1092
SfaNI	GCATC	1 cut(s)	14
SfcI	CTRYAG	1 cut(s)	564
Sfr303I	CCGCGG	1 cut(s)	830
SfuI	TTCGAA	1 cut(s)	88
SgrBI	CCGCGG	1 cut(s)	830
SmlI	CTYRAG	3 cut(s)	515, 590, 1074
SmoI	CTYRAG	3 cut(s)	515, 590, 1074
Sse9I	AATT	6 cut(s)	113, 390, 820, 872, 917, 1100
SseBI	AGGCCT	1 cut(s)	463
SsiI	CCGC	6 cut(s)	124, 284, 827, 829, 1055, 1082
SspMI	CTAG	1 cut(s)	540
StuI	AGGCCT	1 cut(s)	463
StyD4I	CCNGG	2 cut(s)	307, 651
TaqI	TCGA	5 cut(s)	88, 130, 291, 427, 609
TasI	AATT	6 cut(s)	113, 390, 820, 872, 917, 1100
TatI	WGTACW	1 cut(s)	1007
TauI	GCSGC	1 cut(s)	1084
TfiI	GAWTC	1 cut(s)	606
Tru1I	TTAA	3 cut(s)	516, 947, 1103
Tru9I	TTAA	3 cut(s)	516, 947, 1103
TscAI	CASTG	1 cut(s)	1008
TseI	GCWGC	6 cut(s)	158, 563, 572, 575, 749, 935
TspDTI	ATGAA	6 cut(s)	381, 383, 456, 741, 968, 1113
TspGWI	ACGGA	3 cut(s)	97, 439, 1046
TspRI	CASTG	1 cut(s)	1008
Vha464I	CTTAAG	1 cut(s)	515
VspI	ATTAAT	1 cut(s)	1103
XagI	CCTNNNNNAGG	1 cut(s)	653
XapI	RAATTY	2 cut(s)	872, 917
XceI	RCATGY	2 cut(s)	345, 473
XspI	CTAG	1 cut(s)	540

Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.