The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins. Some of these proteins have been shown both in vivo and in vitro to have ubiquitin E3 ligase activity.
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| Species | Orthologous Gene IDs |
|---|---|
| arabidopsis_thaliana | AT5G05830 |
| fragaria_vesca | FvH4_7g23740 FvH4_7g23740 |
| malus_domestica | MD01G1144600.v1.1 MD07G1211200.v1.1 |
| prunus_persica | Prupe.2G244000_v2.0.a1 |
| pyrus_communis | pycom01g16420 pycom07g19470 |
| rosa_chinensis | RchiOBHm_Chr1g0369041 |
| rosa_laevigata | RLG00000027162 |
| rosa_multiflora | Rmu_sc0004250.1_g000028 |
| rosa_roxburghii | Rroxscaffold_4G00288060 |
| rosa_rugosa | Rorug01G0347000 |
| rosa_samantha | Rh1AG354200 Rh1BG317600 Rh1CG332100 Rh1DG348500 |
| rosa_wichuraiana | Rw1G031290 |
| Enzyme | Recognition Site | Cut Count | Positions (bp) |
|---|---|---|---|
| AciI | CCGC | 2 cut(s) | 61, 407 |
| AclWI | GGATC | 3 cut(s) | 97, 180, 394 |
| AcoI | YGGCCR | 1 cut(s) | 465 |
| AcsI | RAATTY | 1 cut(s) | 535 |
| AcuI | CTGAAG | 1 cut(s) | 438 |
| AcvI | CACGTG | 1 cut(s) | 208 |
| AcyI | GRCGYC | 1 cut(s) | 75 |
| AfaI | GTAC | 1 cut(s) | 597 |
| AgeI | ACCGGT | 1 cut(s) | 525 |
| AgsI | TTSAA | 3 cut(s) | 114, 352, 592 |
| AluBI | AGCT | 5 cut(s) | 81, 191, 422, 479, 548 |
| AluI | AGCT | 5 cut(s) | 81, 191, 422, 479, 548 |
| AlwI | GGATC | 3 cut(s) | 97, 180, 394 |
| AlwNI | CAGNNNCTG | 1 cut(s) | 479 |
| AoxI | GGCC | 1 cut(s) | 465 |
| ApeKI | GCWGC | 5 cut(s) | 5, 317, 320, 476, 479 |
| ApoI | RAATTY | 1 cut(s) | 535 |
| AsiGI | ACCGGT | 1 cut(s) | 525 |
| AspS9I | GGNCC | 1 cut(s) | 69 |
| AsuHPI | GGTGA | 2 cut(s) | 50, 515 |
| AsuNHI | GCTAGC | 1 cut(s) | 544 |
| AvaII | GGWCC | 1 cut(s) | 69 |
| BalI | TGGCCA | 1 cut(s) | 467 |
| BauI | CACGAG | 1 cut(s) | 601 |
| BbrPI | CACGTG | 1 cut(s) | 208 |
| BbsI | GAAGAC | 1 cut(s) | 54 |
| BbvCI | CCTCAGC | 2 cut(s) | 192, 339 |
| BbvI | GCAGC | 5 cut(s) | 17, 304, 307, 466, 488 |
| BfaI | CTAG | 1 cut(s) | 545 |
| BfmI | CTRYAG | 1 cut(s) | 229 |
| BisI | GCNGC | 5 cut(s) | 6, 318, 321, 477, 480 |
| BlsI | GCNGC | 5 cut(s) | 7, 319, 322, 478, 481 |
| Bme18I | GGWCC | 1 cut(s) | 69 |
| BmgT120I | GGNCC | 1 cut(s) | 69 |
| BmiI | GGNNCC | 1 cut(s) | 530 |
| BmsI | GCATC | 2 cut(s) | 192, 244 |
| BmtI | GCTAGC | 1 cut(s) | 548 |
| BoxI | GACNNNNGTC | 1 cut(s) | 54 |
| BpiI | GAAGAC | 1 cut(s) | 54 |
| Bpu10I | CCTNAGC | 2 cut(s) | 192, 339 |
| BsaAI | YACGTR | 2 cut(s) | 208, 398 |
| BsaHI | GRCGYC | 1 cut(s) | 75 |
| BsaWI | WCCGGW | 1 cut(s) | 525 |
| BsaXI | ACNNNNNCTCC | 2 cut(s) | 92, 122 |
| Bse118I | RCCGGY | 1 cut(s) | 525 |
| Bse3DI | GCAATG | 1 cut(s) | 468 |
| BseGI | GGATG | 1 cut(s) | 259 |
| BseMI | GCAATG | 1 cut(s) | 468 |
| BseMII | CTCAG | 6 cut(s) | 96, 120, 183, 236, 330, 414 |
| BseRI | GAGGAG | 2 cut(s) | 113, 116 |
| BseXI | GCAGC | 5 cut(s) | 17, 304, 307, 466, 488 |
| BsgI | GTGCAG | 2 cut(s) | 378, 509 |
| BshFI | GGCC | 1 cut(s) | 467 |
| BshTI | ACCGGT | 1 cut(s) | 525 |
| BsiSI | CCGG | 3 cut(s) | 64, 505, 526 |
| BslFI | GGGAC | 1 cut(s) | 239 |
| BsmFI | GGGAC | 1 cut(s) | 239 |
| BsnI | GGCC | 1 cut(s) | 467 |
| Bsp143I | GATC | 3 cut(s) | 89, 172, 386 |
| BspACI | CCGC | 2 cut(s) | 61, 407 |
| BspANI | GGCC | 1 cut(s) | 467 |
| BspCNI | CTCAG | 6 cut(s) | 95, 121, 184, 237, 331, 415 |
| BspHI | TCATGA | 1 cut(s) | 265 |
| BspLI | GGNNCC | 1 cut(s) | 530 |
| BspOI | GCTAGC | 1 cut(s) | 548 |
| BspPI | GGATC | 3 cut(s) | 97, 180, 394 |
| BsrDI | GCAATG | 1 cut(s) | 468 |
| BsrFI | RCCGGY | 1 cut(s) | 525 |
| BssAI | RCCGGY | 1 cut(s) | 525 |
| BssMI | GATC | 3 cut(s) | 89, 172, 386 |
| BssNI | GRCGYC | 1 cut(s) | 75 |
| BssSI | CACGAG | 1 cut(s) | 601 |
| Bst2BI | CACGAG | 1 cut(s) | 601 |
| Bst4CI | ACNGT | 2 cut(s) | 230, 333 |
| BstACI | GRCGYC | 1 cut(s) | 75 |
| BstBAI | YACGTR | 2 cut(s) | 208, 398 |
| BstC8I | GCNNGC | 2 cut(s) | 79, 546 |
| BstDEI | CTNAG | 6 cut(s) | 82, 129, 192, 245, 339, 423 |
| BstEII | GGTNACC | 2 cut(s) | 56, 521 |
| BstF5I | GGATG | 1 cut(s) | 259 |
| BstKTI | GATC | 3 cut(s) | 92, 175, 389 |
| BstMBI | GATC | 3 cut(s) | 89, 172, 386 |
| BstMWI | GCNNNNNNNGC | 2 cut(s) | 314, 473 |
| BstPAI | GACNNNNGTC | 1 cut(s) | 54 |
| BstPI | GGTNACC | 2 cut(s) | 56, 521 |
| BstSFI | CTRYAG | 1 cut(s) | 229 |
| BstV1I | GCAGC | 5 cut(s) | 17, 304, 307, 466, 488 |
| BstV2I | GAAGAC | 1 cut(s) | 54 |
| BstX2I | RGATCY | 1 cut(s) | 172 |
| BstYI | RGATCY | 1 cut(s) | 172 |
| BsuRI | GGCC | 1 cut(s) | 467 |
| BtsCI | GGATG | 1 cut(s) | 259 |
| BtsI | GCAGTG | 1 cut(s) | 443 |
| BtsIMutI | CAGTG | 3 cut(s) | 174, 338, 443 |
| Cac8I | GCNNGC | 2 cut(s) | 79, 546 |
| CaiI | CAGNNNCTG | 1 cut(s) | 479 |
| CciI | TCATGA | 1 cut(s) | 265 |
| Cfr10I | RCCGGY | 1 cut(s) | 525 |
| Cfr13I | GGNCC | 1 cut(s) | 69 |
| CseI | GACGC | 2 cut(s) | 83, 114 |
| Csp6I | GTAC | 1 cut(s) | 596 |
| CspAI | ACCGGT | 1 cut(s) | 525 |
| CviAII | CATG | 2 cut(s) | 250, 266 |
| CviQI | GTAC | 1 cut(s) | 596 |
| DdeI | CTNAG | 6 cut(s) | 82, 129, 192, 245, 339, 423 |
| DpnI | GATC | 3 cut(s) | 91, 174, 388 |
| DpnII | GATC | 3 cut(s) | 89, 172, 386 |
| EaeI | YGGCCR | 1 cut(s) | 465 |
| Eco47I | GGWCC | 1 cut(s) | 69 |
| Eco57I | CTGAAG | 1 cut(s) | 438 |
| Eco72I | CACGTG | 1 cut(s) | 208 |
| Eco91I | GGTNACC | 2 cut(s) | 56, 521 |
| EcoO65I | GGTNACC | 2 cut(s) | 56, 521 |
| FaeI | CATG | 2 cut(s) | 253, 269 |
| FaiI | YATR | 4 cut(s) | 11, 251, 267, 554 |
| FaqI | GGGAC | 1 cut(s) | 239 |
| FatI | CATG | 2 cut(s) | 249, 265 |
| FauI | CCCGC | 1 cut(s) | 400 |
| Fnu4HI | GCNGC | 5 cut(s) | 6, 318, 321, 477, 480 |
| FokI | GGATG | 1 cut(s) | 266 |
| Fsp4HI | GCNGC | 5 cut(s) | 6, 318, 321, 477, 480 |
| FspBI | CTAG | 1 cut(s) | 545 |
| GluI | GCNGC | 5 cut(s) | 6, 318, 321, 477, 480 |
| HaeIII | GGCC | 1 cut(s) | 467 |
| HapII | CCGG | 3 cut(s) | 64, 505, 526 |
| HgaI | GACGC | 2 cut(s) | 83, 114 |
| Hin1I | GRCGYC | 1 cut(s) | 75 |
| Hin1II | CATG | 2 cut(s) | 253, 269 |
| HinfI | GANTC | 4 cut(s) | 119, 146, 269, 277 |
| HpaII | CCGG | 3 cut(s) | 64, 505, 526 |
| HphI | GGTGA | 2 cut(s) | 50, 515 |
| Hpy188I | TCNGA | 6 cut(s) | 73, 85, 94, 130, 160, 246 |
| Hpy188III | TCNNGA | 4 cut(s) | 176, 266, 532, 603 |
| Hpy99I | CGWCG | 1 cut(s) | 77 |
| HpyCH4III | ACNGT | 2 cut(s) | 230, 333 |
| HpyCH4IV | ACGT | 3 cut(s) | 24, 207, 397 |
| HpyCH4V | TGCA | 5 cut(s) | 205, 257, 395, 461, 490 |
| HpyF10VI | GCNNNNNNNGC | 2 cut(s) | 314, 473 |
| HpyF3I | CTNAG | 6 cut(s) | 82, 129, 192, 245, 339, 423 |
| HpySE526I | ACGT | 3 cut(s) | 24, 207, 397 |
| Hsp92I | GRCGYC | 1 cut(s) | 75 |
| Hsp92II | CATG | 2 cut(s) | 253, 269 |
| Kzo9I | GATC | 3 cut(s) | 89, 172, 386 |
| LmnI | GCTCC | 1 cut(s) | 433 |
| Lsp1109I | GCAGC | 5 cut(s) | 17, 304, 307, 466, 488 |
| LweI | GCATC | 2 cut(s) | 192, 244 |
| MaeI | CTAG | 1 cut(s) | 545 |
| MaeII | ACGT | 3 cut(s) | 24, 207, 397 |
| MaeIII | GTNAC | 4 cut(s) | 56, 362, 412, 521 |
| MalI | GATC | 3 cut(s) | 91, 174, 388 |
| MboI | GATC | 3 cut(s) | 89, 172, 386 |
| MboII | GAAGA | 3 cut(s) | 53, 56, 59 |
| MflI | RGATCY | 1 cut(s) | 172 |
| MlsI | TGGCCA | 1 cut(s) | 467 |
| MluCI | AATT | 1 cut(s) | 535 |
| MluNI | TGGCCA | 1 cut(s) | 467 |
| MlyI | GAGTC | 1 cut(s) | 128 |
| MmeI | TCCRAC | 1 cut(s) | 96 |
| Mox20I | TGGCCA | 1 cut(s) | 467 |
| MscI | TGGCCA | 1 cut(s) | 467 |
| MseI | TTAA | 1 cut(s) | 198 |
| MslI | CAYNNNNRTG | 1 cut(s) | 591 |
| Msp20I | TGGCCA | 1 cut(s) | 467 |
| MspA1I | CMGCKG | 1 cut(s) | 479 |
| MspI | CCGG | 3 cut(s) | 64, 505, 526 |
| MwoI | GCNNNNNNNGC | 2 cut(s) | 314, 473 |
| NdeII | GATC | 3 cut(s) | 89, 172, 386 |
| NheI | GCTAGC | 1 cut(s) | 544 |
| NlaIII | CATG | 2 cut(s) | 253, 269 |
| NlaIV | GGNNCC | 1 cut(s) | 530 |
| NmuCI | GTSAC | 3 cut(s) | 56, 412, 521 |
| PagI | TCATGA | 1 cut(s) | 265 |
| PcsI | WCGNNNNNNNCGW | 1 cut(s) | 93 |
| PfeI | GAWTC | 3 cut(s) | 146, 269, 277 |
| PinAI | ACCGGT | 1 cut(s) | 525 |
| PkrI | GCNGC | 5 cut(s) | 7, 319, 322, 478, 481 |
| PleI | GAGTC | 1 cut(s) | 127 |
| PmaCI | CACGTG | 1 cut(s) | 208 |
| PmlI | CACGTG | 1 cut(s) | 208 |
| PpsI | GAGTC | 1 cut(s) | 127 |
| Ppu21I | YACGTR | 2 cut(s) | 208, 398 |
| PshAI | GACNNNNGTC | 1 cut(s) | 54 |
| PspCI | CACGTG | 1 cut(s) | 208 |
| PspEI | GGTNACC | 2 cut(s) | 56, 521 |
| PspN4I | GGNNCC | 1 cut(s) | 530 |
| PspPI | GGNCC | 1 cut(s) | 69 |
| PstNI | CAGNNNCTG | 1 cut(s) | 479 |
| PsuI | RGATCY | 1 cut(s) | 172 |
| PvuII | CAGCTG | 1 cut(s) | 479 |
| RsaI | GTAC | 1 cut(s) | 597 |
| RsaNI | GTAC | 1 cut(s) | 596 |
| RseI | CAYNNNNRTG | 1 cut(s) | 591 |
| SaqAI | TTAA | 1 cut(s) | 198 |
| SatI | GCNGC | 5 cut(s) | 6, 318, 321, 477, 480 |
| Sau3AI | GATC | 3 cut(s) | 89, 172, 386 |
| Sau96I | GGNCC | 1 cut(s) | 69 |
| SchI | GAGTC | 1 cut(s) | 128 |
| SfaNI | GCATC | 2 cut(s) | 192, 244 |
| SfcI | CTRYAG | 1 cut(s) | 229 |
| SinI | GGWCC | 1 cut(s) | 69 |
| SmiMI | CAYNNNNRTG | 1 cut(s) | 591 |
| Sse9I | AATT | 1 cut(s) | 535 |
| SsiI | CCGC | 2 cut(s) | 61, 407 |
| SspMI | CTAG | 1 cut(s) | 545 |
| TaaI | ACNGT | 2 cut(s) | 230, 333 |
| TaiI | ACGT | 3 cut(s) | 27, 210, 400 |
| TasI | AATT | 1 cut(s) | 535 |
| TfiI | GAWTC | 3 cut(s) | 146, 269, 277 |
| Tru1I | TTAA | 1 cut(s) | 198 |
| Tru9I | TTAA | 1 cut(s) | 198 |
| TscAI | CASTG | 3 cut(s) | 174, 338, 443 |
| TseFI | GTSAC | 3 cut(s) | 56, 412, 521 |
| TseI | GCWGC | 5 cut(s) | 5, 317, 320, 476, 479 |
| Tsp45I | GTSAC | 3 cut(s) | 56, 412, 521 |
| TspDTI | ATGAA | 1 cut(s) | 282 |
| TspGWI | ACGGA | 1 cut(s) | 102 |
| TspRI | CASTG | 3 cut(s) | 174, 338, 443 |
| VpaK11BI | GGWCC | 1 cut(s) | 69 |
| XapI | RAATTY | 1 cut(s) | 535 |
| XspI | CTAG | 1 cut(s) | 545 |