The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins. Some of these proteins have been shown both in vivo and in vitro to have ubiquitin E3 ligase activity.
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| Species | Orthologous Gene IDs |
|---|---|
| arabidopsis_thaliana | AT5G05830 |
| fragaria_vesca | FvH4_7g23740 FvH4_7g23740 |
| malus_domestica | MD01G1144600.v1.1 MD07G1211200.v1.1 |
| prunus_persica | Prupe.2G244000_v2.0.a1 |
| pyrus_communis | pycom01g16420 pycom07g19470 |
| rosa_chinensis | RchiOBHm_Chr1g0369041 |
| rosa_laevigata | RLG00000027162 |
| rosa_multiflora | Rmu_sc0004250.1_g000028 |
| rosa_roxburghii | Rroxscaffold_4G00288060 |
| rosa_rugosa | Rorug01G0347000 |
| rosa_samantha | Rh1AG354200 Rh1BG317600 Rh1CG332100 Rh1DG348500 |
| rosa_wichuraiana | Rw1G031290 |
| Enzyme | Recognition Site | Cut Count | Positions (bp) |
|---|---|---|---|
| AarI | CACCTGC | 1 cut(s) | 482 |
| Acc36I | ACCTGC | 1 cut(s) | 482 |
| AccB1I | GGYRCC | 2 cut(s) | 494, 508 |
| AccI | GTMKAC | 2 cut(s) | 12, 79 |
| AciI | CCGC | 3 cut(s) | 69, 449, 541 |
| AclWI | GGATC | 2 cut(s) | 210, 412 |
| AcvI | CACGTG | 2 cut(s) | 25, 226 |
| AcyI | GRCGYC | 1 cut(s) | 58 |
| AfiI | CCNNNNNNNGG | 3 cut(s) | 98, 268, 505 |
| AgsI | TTSAA | 2 cut(s) | 370, 607 |
| AluBI | AGCT | 5 cut(s) | 87, 307, 326, 440, 563 |
| AluI | AGCT | 5 cut(s) | 87, 307, 326, 440, 563 |
| Alw21I | GWGCWC | 1 cut(s) | 137 |
| AlwI | GGATC | 2 cut(s) | 210, 412 |
| AlwNI | CAGNNNCTG | 1 cut(s) | 152 |
| ApeKI | GCWGC | 5 cut(s) | 5, 335, 338, 479, 482 |
| AspLEI | GCGC | 1 cut(s) | 68 |
| AsuHPI | GGTGA | 3 cut(s) | 226, 251, 530 |
| BaeGI | GKGCMC | 2 cut(s) | 499, 615 |
| BanI | GGYRCC | 2 cut(s) | 494, 508 |
| BauI | CACGAG | 1 cut(s) | 589 |
| BbrPI | CACGTG | 2 cut(s) | 25, 226 |
| Bbv12I | GWGCWC | 1 cut(s) | 137 |
| BbvCI | CCTCAGC | 1 cut(s) | 357 |
| BbvI | GCAGC | 5 cut(s) | 17, 322, 325, 491, 494 |
| BccI | CCATC | 1 cut(s) | 113 |
| BfaI | CTAG | 2 cut(s) | 308, 560 |
| BfoI | RGCGCY | 1 cut(s) | 69 |
| BfuAI | ACCTGC | 1 cut(s) | 482 |
| BglI | GCCNNNNNGGC | 1 cut(s) | 476 |
| BisI | GCNGC | 6 cut(s) | 6, 69, 336, 339, 480, 483 |
| BlsI | GCNGC | 6 cut(s) | 7, 70, 337, 340, 481, 484 |
| BmiI | GGNNCC | 3 cut(s) | 103, 496, 510 |
| BmsI | GCATC | 2 cut(s) | 210, 262 |
| BplI | GAGNNNNNCTC | 2 cut(s) | 86, 118 |
| BpmI | CTGGAG | 2 cut(s) | 121, 227 |
| Bpu10I | CCTNAGC | 2 cut(s) | 263, 357 |
| BsaAI | YACGTR | 3 cut(s) | 25, 226, 416 |
| BsaHI | GRCGYC | 1 cut(s) | 58 |
| BsaJI | CCNNGG | 2 cut(s) | 72, 105 |
| BsaXI | ACNNNNNCTCC | 2 cut(s) | 116, 146 |
| Bsc4I | CCNNNNNNNGG | 3 cut(s) | 98, 268, 505 |
| Bse1I | ACTGG | 2 cut(s) | 138, 480 |
| BseDI | CCNNGG | 2 cut(s) | 72, 105 |
| BseGI | GGATG | 2 cut(s) | 124, 277 |
| BseLI | CCNNNNNNNGG | 3 cut(s) | 98, 268, 505 |
| BseMII | CTCAG | 5 cut(s) | 84, 144, 254, 348, 432 |
| BseNI | ACTGG | 2 cut(s) | 138, 480 |
| BseRI | GAGGAG | 2 cut(s) | 56, 224 |
| BseSI | GKGCMC | 2 cut(s) | 499, 615 |
| BseXI | GCAGC | 5 cut(s) | 17, 322, 325, 491, 494 |
| BseYI | CCCAGC | 1 cut(s) | 62 |
| BsgI | GTGCAG | 2 cut(s) | 396, 524 |
| BshNI | GGYRCC | 2 cut(s) | 494, 508 |
| BsiHKAI | GWGCWC | 1 cut(s) | 137 |
| BsiSI | CCGG | 1 cut(s) | 99 |
| BslFI | GGGAC | 1 cut(s) | 69 |
| BslI | CCNNNNNNNGG | 3 cut(s) | 98, 268, 505 |
| BsmFI | GGGAC | 1 cut(s) | 69 |
| Bsp1286I | GDGCHC | 3 cut(s) | 137, 499, 615 |
| Bsp143I | GATC | 4 cut(s) | 156, 202, 372, 404 |
| BspACI | CCGC | 3 cut(s) | 69, 449, 541 |
| BspCNI | CTCAG | 5 cut(s) | 85, 145, 255, 349, 433 |
| BspHI | TCATGA | 2 cut(s) | 283, 617 |
| BspLI | GGNNCC | 3 cut(s) | 103, 496, 510 |
| BspMI | ACCTGC | 1 cut(s) | 482 |
| BspPI | GGATC | 2 cut(s) | 210, 412 |
| BspT107I | GGYRCC | 2 cut(s) | 494, 508 |
| BsrI | ACTGG | 2 cut(s) | 138, 480 |
| BssECI | CCNNGG | 2 cut(s) | 72, 105 |
| BssMI | GATC | 4 cut(s) | 156, 202, 372, 404 |
| BssNI | GRCGYC | 1 cut(s) | 58 |
| BssSI | CACGAG | 1 cut(s) | 589 |
| Bst2BI | CACGAG | 1 cut(s) | 589 |
| Bst6I | CTCTTC | 1 cut(s) | 122 |
| BstACI | GRCGYC | 1 cut(s) | 58 |
| BstBAI | YACGTR | 3 cut(s) | 25, 226, 416 |
| BstC8I | GCNNGC | 1 cut(s) | 507 |
| BstDEI | CTNAG | 5 cut(s) | 93, 153, 263, 357, 441 |
| BstDSI | CCRYGG | 1 cut(s) | 72 |
| BstEII | GGTNACC | 1 cut(s) | 536 |
| BstF5I | GGATG | 2 cut(s) | 124, 277 |
| BstH2I | RGCGCY | 1 cut(s) | 69 |
| BstHHI | GCGC | 1 cut(s) | 68 |
| BstKTI | GATC | 4 cut(s) | 159, 205, 375, 407 |
| BstMBI | GATC | 4 cut(s) | 156, 202, 372, 404 |
| BstMWI | GCNNNNNNNGC | 4 cut(s) | 332, 446, 476, 488 |
| BstPI | GGTNACC | 1 cut(s) | 536 |
| BstSLI | GKGCMC | 2 cut(s) | 499, 615 |
| BstV1I | GCAGC | 5 cut(s) | 17, 322, 325, 491, 494 |
| BstX2I | RGATCY | 1 cut(s) | 202 |
| BstYI | RGATCY | 1 cut(s) | 202 |
| BtgI | CCRYGG | 1 cut(s) | 72 |
| BtsCI | GGATG | 2 cut(s) | 124, 277 |
| BtsI | GCAGTG | 2 cut(s) | 356, 461 |
| BtsIMutI | CAGTG | 5 cut(s) | 145, 198, 356, 461, 473 |
| BveI | ACCTGC | 1 cut(s) | 482 |
| Cac8I | GCNNGC | 1 cut(s) | 507 |
| CaiI | CAGNNNCTG | 1 cut(s) | 152 |
| CciI | TCATGA | 2 cut(s) | 283, 617 |
| CfoI | GCGC | 1 cut(s) | 68 |
| CseI | GACGC | 2 cut(s) | 66, 168 |
| CviAII | CATG | 4 cut(s) | 268, 284, 461, 618 |
| DdeI | CTNAG | 5 cut(s) | 93, 153, 263, 357, 441 |
| DpnI | GATC | 4 cut(s) | 158, 204, 374, 406 |
| DpnII | GATC | 4 cut(s) | 156, 202, 372, 404 |
| Eam1104I | CTCTTC | 1 cut(s) | 122 |
| EarI | CTCTTC | 1 cut(s) | 122 |
| EciI | GGCGGA | 1 cut(s) | 464 |
| Eco72I | CACGTG | 2 cut(s) | 25, 226 |
| Eco91I | GGTNACC | 1 cut(s) | 536 |
| EcoO65I | GGTNACC | 1 cut(s) | 536 |
| FaeI | CATG | 4 cut(s) | 271, 287, 464, 621 |
| FaiI | YATR | 6 cut(s) | 269, 285, 400, 462, 569, 619 |
| FaqI | GGGAC | 1 cut(s) | 69 |
| FatI | CATG | 4 cut(s) | 267, 283, 460, 617 |
| FblI | GTMKAC | 2 cut(s) | 12, 79 |
| Fnu4HI | GCNGC | 6 cut(s) | 6, 69, 336, 339, 480, 483 |
| FokI | GGATG | 2 cut(s) | 131, 284 |
| Fsp4HI | GCNGC | 6 cut(s) | 6, 69, 336, 339, 480, 483 |
| FspBI | CTAG | 2 cut(s) | 308, 560 |
| GlaI | GCGC | 1 cut(s) | 67 |
| GluI | GCNGC | 6 cut(s) | 6, 69, 336, 339, 480, 483 |
| GsaI | CCCAGC | 1 cut(s) | 66 |
| GsuI | CTGGAG | 2 cut(s) | 121, 227 |
| HaeII | RGCGCY | 1 cut(s) | 69 |
| HapII | CCGG | 1 cut(s) | 99 |
| HgaI | GACGC | 2 cut(s) | 66, 168 |
| HhaI | GCGC | 1 cut(s) | 68 |
| Hin1I | GRCGYC | 1 cut(s) | 58 |
| Hin1II | CATG | 4 cut(s) | 271, 287, 464, 621 |
| Hin6I | GCGC | 1 cut(s) | 66 |
| HinP1I | GCGC | 1 cut(s) | 66 |
| HincII | GTYRAC | 1 cut(s) | 80 |
| HindII | GTYRAC | 1 cut(s) | 80 |
| HinfI | GANTC | 7 cut(s) | 95, 143, 170, 280, 287, 295, 443 |
| HpaII | CCGG | 1 cut(s) | 99 |
| HphI | GGTGA | 3 cut(s) | 226, 251, 530 |
| Hpy166II | GTNNAC | 2 cut(s) | 13, 80 |
| Hpy188I | TCNGA | 4 cut(s) | 106, 115, 154, 184 |
| Hpy188III | TCNNGA | 5 cut(s) | 206, 284, 370, 547, 618 |
| Hpy8I | GTNNAC | 2 cut(s) | 13, 80 |
| Hpy99I | CGWCG | 2 cut(s) | 84, 184 |
| HpyCH4IV | ACGT | 4 cut(s) | 24, 82, 225, 415 |
| HpyCH4V | TGCA | 6 cut(s) | 223, 249, 275, 413, 505, 578 |
| HpyF10VI | GCNNNNNNNGC | 4 cut(s) | 332, 446, 476, 488 |
| HpyF3I | CTNAG | 5 cut(s) | 93, 153, 263, 357, 441 |
| HpySE526I | ACGT | 4 cut(s) | 24, 82, 225, 415 |
| Hsp92I | GRCGYC | 1 cut(s) | 58 |
| Hsp92II | CATG | 4 cut(s) | 271, 287, 464, 621 |
| HspAI | GCGC | 1 cut(s) | 66 |
| Kzo9I | GATC | 4 cut(s) | 156, 202, 372, 404 |
| LmnI | GCTCC | 3 cut(s) | 107, 140, 451 |
| Lsp1109I | GCAGC | 5 cut(s) | 17, 322, 325, 491, 494 |
| LweI | GCATC | 2 cut(s) | 210, 262 |
| MaeI | CTAG | 2 cut(s) | 308, 560 |
| MaeII | ACGT | 4 cut(s) | 24, 82, 225, 415 |
| MaeIII | GTNAC | 3 cut(s) | 257, 380, 536 |
| MalI | GATC | 4 cut(s) | 158, 204, 374, 406 |
| MboI | GATC | 4 cut(s) | 156, 202, 372, 404 |
| MboII | GAAGA | 2 cut(s) | 139, 229 |
| MflI | RGATCY | 1 cut(s) | 202 |
| MhlI | GDGCHC | 3 cut(s) | 137, 499, 615 |
| MlyI | GAGTC | 3 cut(s) | 104, 152, 452 |
| MmeI | TCCRAC | 2 cut(s) | 93, 162 |
| MslI | CAYNNNNRTG | 1 cut(s) | 606 |
| MspI | CCGG | 1 cut(s) | 99 |
| MwoI | GCNNNNNNNGC | 4 cut(s) | 332, 446, 476, 488 |
| NdeII | GATC | 4 cut(s) | 156, 202, 372, 404 |
| NlaIII | CATG | 4 cut(s) | 271, 287, 464, 621 |
| NlaIV | GGNNCC | 3 cut(s) | 103, 496, 510 |
| NmuCI | GTSAC | 2 cut(s) | 257, 536 |
| PagI | TCATGA | 2 cut(s) | 283, 617 |
| PaqCI | CACCTGC | 1 cut(s) | 482 |
| PfeI | GAWTC | 4 cut(s) | 170, 280, 287, 295 |
| PkrI | GCNGC | 6 cut(s) | 7, 70, 337, 340, 481, 484 |
| PleI | GAGTC | 3 cut(s) | 103, 151, 451 |
| PmaCI | CACGTG | 2 cut(s) | 25, 226 |
| PmlI | CACGTG | 2 cut(s) | 25, 226 |
| PpsI | GAGTC | 3 cut(s) | 103, 151, 451 |
| Ppu21I | YACGTR | 3 cut(s) | 25, 226, 416 |
| PspCI | CACGTG | 2 cut(s) | 25, 226 |
| PspEI | GGTNACC | 1 cut(s) | 536 |
| PspFI | CCCAGC | 1 cut(s) | 62 |
| PspN4I | GGNNCC | 3 cut(s) | 103, 496, 510 |
| PstNI | CAGNNNCTG | 1 cut(s) | 152 |
| PsuI | RGATCY | 1 cut(s) | 202 |
| RseI | CAYNNNNRTG | 1 cut(s) | 606 |
| SalI | GTCGAC | 1 cut(s) | 78 |
| SatI | GCNGC | 6 cut(s) | 6, 69, 336, 339, 480, 483 |
| Sau3AI | GATC | 4 cut(s) | 156, 202, 372, 404 |
| SchI | GAGTC | 3 cut(s) | 104, 152, 452 |
| SduI | GDGCHC | 3 cut(s) | 137, 499, 615 |
| SfaNI | GCATC | 2 cut(s) | 210, 262 |
| SmiMI | CAYNNNNRTG | 1 cut(s) | 606 |
| SsiI | CCGC | 3 cut(s) | 69, 449, 541 |
| SspMI | CTAG | 2 cut(s) | 308, 560 |
| TaiI | ACGT | 4 cut(s) | 27, 85, 228, 418 |
| TaqI | TCGA | 1 cut(s) | 79 |
| TauI | GCSGC | 1 cut(s) | 71 |
| TfiI | GAWTC | 4 cut(s) | 170, 280, 287, 295 |
| TscAI | CASTG | 5 cut(s) | 145, 198, 356, 461, 480 |
| TseFI | GTSAC | 2 cut(s) | 257, 536 |
| TseI | GCWGC | 5 cut(s) | 5, 335, 338, 479, 482 |
| Tsp45I | GTSAC | 2 cut(s) | 257, 536 |
| TspDTI | ATGAA | 2 cut(s) | 300, 480 |
| TspRI | CASTG | 5 cut(s) | 145, 198, 356, 461, 480 |
| XmiI | GTMKAC | 2 cut(s) | 12, 79 |
| XspI | CTAG | 2 cut(s) | 308, 560 |