The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins. Some of these proteins have been shown both in vivo and in vitro to have ubiquitin E3 ligase activity.
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| Species | Orthologous Gene IDs |
|---|---|
| fragaria_vesca | FvH4_6g12450 FvH4_6g12450 FvH4_6g12450 FvH4_6g12450 |
| malus_domestica | MD04G1142100.v1.1 MD12G1156700.v1.1 |
| prunus_persica | Prupe.6G267500_v2.0.a1 Prupe.6G267500_v2.0.a1 Prupe.6G267500_v2.0.a1 Prupe.6G267500_v2.0.a1 |
| pyrus_communis | pycom04g12910 pycom12g14890 |
| rosa_chinensis | RchiOBHm_Chr3g0464261 |
| rosa_laevigata | RLG00000024712 |
| rosa_roxburghii | Rroxscaffold_6G00415890 |
| rosa_rugosa | Rorug03G0071200 |
| rosa_samantha | Rh3BG133000 Rh3CG135200 Rh3DG134400 |
| rosa_wichuraiana | Rw3G010880 |
| Enzyme | Recognition Site | Cut Count | Positions (bp) |
|---|---|---|---|
| AasI | GACNNNNNNGTC | 2 cut(s) | 59, 215 |
| AciI | CCGC | 3 cut(s) | 34, 120, 242 |
| AclI | AACGTT | 1 cut(s) | 648 |
| AclWI | GGATC | 2 cut(s) | 34, 152 |
| AcoI | YGGCCR | 1 cut(s) | 574 |
| AfaI | GTAC | 1 cut(s) | 137 |
| AfiI | CCNNNNNNNGG | 1 cut(s) | 167 |
| AflII | CTTAAG | 1 cut(s) | 43 |
| AgsI | TTSAA | 3 cut(s) | 341, 406, 646 |
| AhdI | GACNNNNNGTC | 1 cut(s) | 85 |
| AjnI | CCWGG | 2 cut(s) | 185, 538 |
| AjuI | GAANNNNNNNTTGG | 2 cut(s) | 219, 251 |
| AleI | CACNNNNGTG | 1 cut(s) | 36 |
| AluBI | AGCT | 5 cut(s) | 223, 298, 374, 524, 564 |
| AluI | AGCT | 5 cut(s) | 223, 298, 374, 524, 564 |
| Alw26I | GTCTC | 3 cut(s) | 157, 181, 535 |
| AlwI | GGATC | 2 cut(s) | 34, 152 |
| AlwNI | CAGNNNCTG | 1 cut(s) | 63 |
| AoxI | GGCC | 3 cut(s) | 239, 542, 574 |
| ApaI | GGGCCC | 1 cut(s) | 546 |
| ApeKI | GCWGC | 4 cut(s) | 57, 371, 374, 524 |
| ArsI | GACNNNNNNTTYG | 2 cut(s) | 107, 139 |
| AspLEI | GCGC | 2 cut(s) | 50, 392 |
| AspS9I | GGNCC | 5 cut(s) | 217, 239, 464, 542, 543 |
| AsuHPI | GGTGA | 1 cut(s) | 23 |
| AvaII | GGWCC | 2 cut(s) | 217, 464 |
| AxyI | CCTNAGG | 1 cut(s) | 162 |
| BaeGI | GKGCMC | 1 cut(s) | 546 |
| BalI | TGGCCA | 1 cut(s) | 576 |
| BanII | GRGCYC | 1 cut(s) | 546 |
| BbvI | GCAGC | 4 cut(s) | 69, 361, 383, 511 |
| BccI | CCATC | 1 cut(s) | 585 |
| BceAI | ACGGC | 2 cut(s) | 21, 70 |
| BcgI | CGANNNNNNTGC | 2 cut(s) | 560, 594 |
| BciT130I | CCWGG | 2 cut(s) | 187, 540 |
| BciVI | GTATCC | 1 cut(s) | 547 |
| BcoDI | GTCTC | 3 cut(s) | 157, 181, 535 |
| BfmI | CTRYAG | 1 cut(s) | 525 |
| BfoI | RGCGCY | 1 cut(s) | 51 |
| BfrI | CTTAAG | 1 cut(s) | 43 |
| BfuI | GTATCC | 1 cut(s) | 547 |
| BisI | GCNGC | 5 cut(s) | 58, 242, 372, 375, 525 |
| BlsI | GCNGC | 5 cut(s) | 59, 243, 373, 376, 526 |
| Bme1390I | CCNGG | 2 cut(s) | 187, 540 |
| Bme18I | GGWCC | 2 cut(s) | 217, 464 |
| BmeRI | GACNNNNNGTC | 1 cut(s) | 85 |
| BmgT120I | GGNCC | 5 cut(s) | 217, 239, 464, 542, 543 |
| BmiI | GGNNCC | 3 cut(s) | 333, 544, 584 |
| BmrFI | CCNGG | 2 cut(s) | 187, 540 |
| BmsI | GCATC | 1 cut(s) | 521 |
| BsaI | GGTCTC | 1 cut(s) | 181 |
| BsaJI | CCNNGG | 2 cut(s) | 539, 549 |
| Bsc4I | CCNNNNNNNGG | 1 cut(s) | 167 |
| Bse1I | ACTGG | 1 cut(s) | 439 |
| Bse21I | CCTNAGG | 1 cut(s) | 162 |
| Bse3DI | GCAATG | 1 cut(s) | 460 |
| BseBI | CCWGG | 2 cut(s) | 187, 540 |
| BseDI | CCNNGG | 2 cut(s) | 539, 549 |
| BseGI | GGATG | 1 cut(s) | 367 |
| BseLI | CCNNNNNNNGG | 1 cut(s) | 167 |
| BseMI | GCAATG | 1 cut(s) | 460 |
| BseMII | CTCAG | 5 cut(s) | 113, 153, 192, 477, 546 |
| BseNI | ACTGG | 1 cut(s) | 439 |
| BseSI | GKGCMC | 1 cut(s) | 546 |
| BseXI | GCAGC | 4 cut(s) | 69, 361, 383, 511 |
| BseYI | CCCAGC | 2 cut(s) | 167, 298 |
| BshFI | GGCC | 3 cut(s) | 241, 544, 576 |
| BslI | CCNNNNNNNGG | 1 cut(s) | 167 |
| BsmAI | GTCTC | 3 cut(s) | 157, 181, 535 |
| BsmBI | CGTCTC | 1 cut(s) | 157 |
| BsnI | GGCC | 3 cut(s) | 241, 544, 576 |
| Bso31I | GGTCTC | 1 cut(s) | 181 |
| Bsp120I | GGGCCC | 1 cut(s) | 542 |
| Bsp1286I | GDGCHC | 1 cut(s) | 546 |
| Bsp143I | GATC | 2 cut(s) | 26, 157 |
| BspACI | CCGC | 3 cut(s) | 34, 120, 242 |
| BspANI | GGCC | 3 cut(s) | 241, 544, 576 |
| BspCNI | CTCAG | 5 cut(s) | 112, 154, 191, 478, 545 |
| BspLI | GGNNCC | 3 cut(s) | 333, 544, 584 |
| BspMAI | CTGCAG | 1 cut(s) | 529 |
| BspPI | GGATC | 2 cut(s) | 34, 152 |
| BspTI | CTTAAG | 1 cut(s) | 43 |
| BspTNI | GGTCTC | 1 cut(s) | 181 |
| BsrDI | GCAATG | 1 cut(s) | 460 |
| BsrI | ACTGG | 1 cut(s) | 439 |
| BssECI | CCNNGG | 2 cut(s) | 539, 549 |
| BssMI | GATC | 2 cut(s) | 26, 157 |
| Bst2UI | CCWGG | 2 cut(s) | 187, 540 |
| Bst4CI | ACNGT | 1 cut(s) | 212 |
| Bst6I | CTCTTC | 1 cut(s) | 202 |
| BstAFI | CTTAAG | 1 cut(s) | 43 |
| BstAPI | GCANNNNNTGC | 1 cut(s) | 63 |
| BstC8I | GCNNGC | 1 cut(s) | 451 |
| BstDEI | CTNAG | 5 cut(s) | 99, 162, 178, 486, 532 |
| BstDSI | CCRYGG | 1 cut(s) | 549 |
| BstF5I | GGATG | 1 cut(s) | 367 |
| BstH2I | RGCGCY | 1 cut(s) | 51 |
| BstHHI | GCGC | 2 cut(s) | 50, 392 |
| BstKTI | GATC | 2 cut(s) | 29, 160 |
| BstMAI | GTCTC | 3 cut(s) | 157, 181, 535 |
| BstMBI | GATC | 2 cut(s) | 26, 157 |
| BstMWI | GCNNNNNNNGC | 5 cut(s) | 54, 63, 309, 509, 533 |
| BstNI | CCWGG | 2 cut(s) | 187, 540 |
| BstSCI | CCNGG | 2 cut(s) | 185, 538 |
| BstSFI | CTRYAG | 1 cut(s) | 525 |
| BstSLI | GKGCMC | 1 cut(s) | 546 |
| BstV1I | GCAGC | 4 cut(s) | 69, 361, 383, 511 |
| BstX2I | RGATCY | 1 cut(s) | 26 |
| BstXI | CCANNNNNNTGG | 1 cut(s) | 326 |
| BstYI | RGATCY | 1 cut(s) | 26 |
| Bsu36I | CCTNAGG | 1 cut(s) | 162 |
| BsuI | GTATCC | 1 cut(s) | 547 |
| BsuRI | GGCC | 3 cut(s) | 241, 544, 576 |
| BtgI | CCRYGG | 1 cut(s) | 549 |
| BtsCI | GGATG | 1 cut(s) | 367 |
| BtsI | GCAGTG | 1 cut(s) | 385 |
| BtsIMutI | CAGTG | 1 cut(s) | 385 |
| Cac8I | GCNNGC | 1 cut(s) | 451 |
| CaiI | CAGNNNCTG | 1 cut(s) | 63 |
| CfoI | GCGC | 2 cut(s) | 50, 392 |
| Cfr13I | GGNCC | 5 cut(s) | 217, 239, 464, 542, 543 |
| CseI | GACGC | 2 cut(s) | 49, 83 |
| Csp6I | GTAC | 1 cut(s) | 136 |
| CviAII | CATG | 3 cut(s) | 320, 572, 630 |
| CviQI | GTAC | 1 cut(s) | 136 |
| DdeI | CTNAG | 5 cut(s) | 99, 162, 178, 486, 532 |
| DpnI | GATC | 2 cut(s) | 28, 159 |
| DpnII | GATC | 2 cut(s) | 26, 157 |
| DrdI | GACNNNNNNGTC | 2 cut(s) | 59, 215 |
| DriI | GACNNNNNGTC | 1 cut(s) | 85 |
| DseDI | GACNNNNNNGTC | 2 cut(s) | 59, 215 |
| EaeI | YGGCCR | 1 cut(s) | 574 |
| Eam1104I | CTCTTC | 1 cut(s) | 202 |
| Eam1105I | GACNNNNNGTC | 1 cut(s) | 85 |
| EarI | CTCTTC | 1 cut(s) | 202 |
| Eco24I | GRGCYC | 1 cut(s) | 546 |
| Eco31I | GGTCTC | 1 cut(s) | 181 |
| Eco47I | GGWCC | 2 cut(s) | 217, 464 |
| Eco81I | CCTNAGG | 1 cut(s) | 162 |
| EcoO109I | RGGNCCY | 2 cut(s) | 542, 543 |
| EcoRII | CCWGG | 2 cut(s) | 185, 538 |
| EcoT38I | GRGCYC | 1 cut(s) | 546 |
| Esp3I | CGTCTC | 1 cut(s) | 157 |
| FaeI | CATG | 3 cut(s) | 323, 575, 633 |
| FaiI | YATR | 8 cut(s) | 127, 321, 436, 573, 608, 626, 631, 658 |
| FatI | CATG | 3 cut(s) | 319, 571, 629 |
| FauI | CCCGC | 1 cut(s) | 113 |
| Fnu4HI | GCNGC | 5 cut(s) | 58, 242, 372, 375, 525 |
| FokI | GGATG | 1 cut(s) | 374 |
| FriOI | GRGCYC | 1 cut(s) | 546 |
| Fsp4HI | GCNGC | 5 cut(s) | 58, 242, 372, 375, 525 |
| GlaI | GCGC | 2 cut(s) | 49, 391 |
| GluI | GCNGC | 5 cut(s) | 58, 242, 372, 375, 525 |
| GsaI | CCCAGC | 2 cut(s) | 171, 302 |
| HaeII | RGCGCY | 1 cut(s) | 51 |
| HaeIII | GGCC | 3 cut(s) | 241, 544, 576 |
| HgaI | GACGC | 2 cut(s) | 49, 83 |
| HhaI | GCGC | 2 cut(s) | 50, 392 |
| Hin1II | CATG | 3 cut(s) | 323, 575, 633 |
| Hin6I | GCGC | 2 cut(s) | 48, 390 |
| HinP1I | GCGC | 2 cut(s) | 48, 390 |
| HindIII | AAGCTT | 1 cut(s) | 562 |
| HinfI | GANTC | 2 cut(s) | 182, 323 |
| HphI | GGTGA | 1 cut(s) | 23 |
| Hpy166II | GTNNAC | 1 cut(s) | 483 |
| Hpy188I | TCNGA | 4 cut(s) | 73, 157, 181, 208 |
| Hpy188III | TCNNGA | 1 cut(s) | 161 |
| Hpy8I | GTNNAC | 1 cut(s) | 483 |
| Hpy99I | CGWCG | 4 cut(s) | 56, 77, 86, 134 |
| HpyAV | CCTTC | 2 cut(s) | 157, 605 |
| HpyCH4III | ACNGT | 1 cut(s) | 212 |
| HpyCH4IV | ACGT | 2 cut(s) | 9, 648 |
| HpyCH4V | TGCA | 5 cut(s) | 259, 357, 449, 512, 527 |
| HpyF10VI | GCNNNNNNNGC | 5 cut(s) | 54, 63, 309, 509, 533 |
| HpyF3I | CTNAG | 5 cut(s) | 99, 162, 178, 486, 532 |
| HpySE526I | ACGT | 2 cut(s) | 9, 648 |
| Hsp92II | CATG | 3 cut(s) | 323, 575, 633 |
| HspAI | GCGC | 2 cut(s) | 48, 390 |
| Kzo9I | GATC | 2 cut(s) | 26, 157 |
| Lsp1109I | GCAGC | 4 cut(s) | 69, 361, 383, 511 |
| LweI | GCATC | 1 cut(s) | 521 |
| MaeII | ACGT | 2 cut(s) | 9, 648 |
| MaeIII | GTNAC | 3 cut(s) | 38, 92, 416 |
| MalI | GATC | 2 cut(s) | 28, 159 |
| MboI | GATC | 2 cut(s) | 26, 157 |
| MboII | GAAGA | 1 cut(s) | 189 |
| MflI | RGATCY | 1 cut(s) | 26 |
| MhlI | GDGCHC | 1 cut(s) | 546 |
| MlsI | TGGCCA | 1 cut(s) | 576 |
| MluCI | AATT | 5 cut(s) | 139, 228, 249, 341, 408 |
| MluNI | TGGCCA | 1 cut(s) | 576 |
| MmeI | TCCRAC | 1 cut(s) | 96 |
| MnlI | CCTC | 4 cut(s) | 157, 205, 556, 596 |
| Mox20I | TGGCCA | 1 cut(s) | 576 |
| MscI | TGGCCA | 1 cut(s) | 576 |
| MseI | TTAA | 3 cut(s) | 44, 252, 411 |
| MslI | CAYNNNNRTG | 1 cut(s) | 36 |
| Msp20I | TGGCCA | 1 cut(s) | 576 |
| MspA1I | CMGCKG | 3 cut(s) | 298, 374, 524 |
| MspCI | CTTAAG | 1 cut(s) | 43 |
| MspR9I | CCNGG | 2 cut(s) | 187, 540 |
| MvaI | CCWGG | 2 cut(s) | 187, 540 |
| MwoI | GCNNNNNNNGC | 5 cut(s) | 54, 63, 309, 509, 533 |
| NdeII | GATC | 2 cut(s) | 26, 157 |
| NlaIII | CATG | 3 cut(s) | 323, 575, 633 |
| NlaIV | GGNNCC | 3 cut(s) | 333, 544, 584 |
| NmuCI | GTSAC | 1 cut(s) | 38 |
| OliI | CACNNNNGTG | 1 cut(s) | 36 |
| PfeI | GAWTC | 2 cut(s) | 182, 323 |
| PfoI | TCCNGGA | 1 cut(s) | 185 |
| PkrI | GCNGC | 5 cut(s) | 59, 243, 373, 376, 526 |
| Psp1406I | AACGTT | 1 cut(s) | 648 |
| Psp6I | CCWGG | 2 cut(s) | 185, 538 |
| PspFI | CCCAGC | 2 cut(s) | 167, 298 |
| PspGI | CCWGG | 2 cut(s) | 185, 538 |
| PspN4I | GGNNCC | 3 cut(s) | 333, 544, 584 |
| PspOMI | GGGCCC | 1 cut(s) | 542 |
| PspPI | GGNCC | 5 cut(s) | 217, 239, 464, 542, 543 |
| PstI | CTGCAG | 1 cut(s) | 529 |
| PstNI | CAGNNNCTG | 1 cut(s) | 63 |
| PsuI | RGATCY | 1 cut(s) | 26 |
| PvuII | CAGCTG | 3 cut(s) | 298, 374, 524 |
| RsaI | GTAC | 1 cut(s) | 137 |
| RsaNI | GTAC | 1 cut(s) | 136 |
| RseI | CAYNNNNRTG | 1 cut(s) | 36 |
| SaqAI | TTAA | 3 cut(s) | 44, 252, 411 |
| SatI | GCNGC | 5 cut(s) | 58, 242, 372, 375, 525 |
| Sau3AI | GATC | 2 cut(s) | 26, 157 |
| Sau96I | GGNCC | 5 cut(s) | 217, 239, 464, 542, 543 |
| ScrFI | CCNGG | 2 cut(s) | 187, 540 |
| SduI | GDGCHC | 1 cut(s) | 546 |
| SetI | ASST | 9 cut(s) | 12, 225, 258, 300, 376, 428, 526, 566, 651 |
| SfaNI | GCATC | 1 cut(s) | 521 |
| SfcI | CTRYAG | 1 cut(s) | 525 |
| SinI | GGWCC | 2 cut(s) | 217, 464 |
| SmiMI | CAYNNNNRTG | 1 cut(s) | 36 |
| SmlI | CTYRAG | 1 cut(s) | 43 |
| SmoI | CTYRAG | 1 cut(s) | 43 |
| Sse9I | AATT | 5 cut(s) | 139, 228, 249, 341, 408 |
| SsiI | CCGC | 3 cut(s) | 34, 120, 242 |
| StyD4I | CCNGG | 2 cut(s) | 185, 538 |
| TaaI | ACNGT | 1 cut(s) | 212 |
| TaiI | ACGT | 2 cut(s) | 12, 651 |
| TaqI | TCGA | 1 cut(s) | 225 |
| TaqII | GACCGA | 1 cut(s) | 205 |
| TasI | AATT | 5 cut(s) | 139, 228, 249, 341, 408 |
| TatI | WGTACW | 1 cut(s) | 135 |
| TauI | GCSGC | 1 cut(s) | 244 |
| TfiI | GAWTC | 2 cut(s) | 182, 323 |
| Tru1I | TTAA | 3 cut(s) | 44, 252, 411 |
| Tru9I | TTAA | 3 cut(s) | 44, 252, 411 |
| TscAI | CASTG | 1 cut(s) | 392 |
| TseFI | GTSAC | 1 cut(s) | 38 |
| TseI | GCWGC | 4 cut(s) | 57, 371, 374, 524 |
| Tsp45I | GTSAC | 1 cut(s) | 38 |
| TspDTI | ATGAA | 1 cut(s) | 336 |
| TspGWI | ACGGA | 2 cut(s) | 566, 642 |
| TspRI | CASTG | 1 cut(s) | 392 |
| Vha464I | CTTAAG | 1 cut(s) | 43 |
| VpaK11BI | GGWCC | 2 cut(s) | 217, 464 |