RLG00000024712

The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins. Some of these proteins have been shown both in vivo and in vitro to have ubiquitin E3 ligase activity.

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
rosa_laevigata
Chr5
OG0011575
Physical Location & Seq
Reverse (-)
38471155 .. 38473086
1932 bp
Loading structure...
UTR
Exon/CDS
Intron
RLM00000024712

Sequence Viewer

Length: 711 bp
ATGTCCGGCGTCGATTTAGAGCACGGCGGTGCTGCTCAAACCCACCGCCTCTCCTTCTCCAGGAGTGACGTCAGCGGTGACGGCAGCGTCTGCTTCTCCGACGCGGACGACGGGTCGTGCTACTCGCAGTTCTTTTCGACCAACGGCGGGTCGTACGACGAGTACAACTTTGCCGCTTTTGTGTCTGATCCTGCTGAGGCCGGAGTGGTCGGGGTTTCGTCGTCGGAGTCTAGGAGAGACTCGTCGGTTTCGGACTGTTCGGTCCATGTCGTGGAAATTGAGGTTGGGCCGCCGGAAATTAAGGTGCATTTGGATAGAGTAGAGAGAGATTGTCGGATTTGCCATCTGGGCTTGGAGAGTAACAGCCATGAATCCGGAGCTCCGATTGACTTGGGCTGTTCTTGCAAAGATGATCTGGGTTCAGCCCACCGGAACTGTGCTGATGCTTGGTTCAAGATCAAGGGCAACAAGATCTGTGAGATTTGTCATTCAATTGCCCGCAACATTGTTGGGCCTAATGACACTGAGATGATTGAGCAGCTGAATAATGAAGCCACTAGTGCCTCAGCAACGGCTGCAGTTTCAGCACCAGGGCCTTCAACAGAGACTCAAAGCTTTTGGCATGGTCATCGCTTCCTCAATTTTCTTCTTGCTTGTATGGTATTTGCTTTTGTCATATCATGGCTCTTTCACTTCAACGTTCCTTCGTGA
Functional Annotation
Gene Ontology
Molecular Function
Biological Process
Cellular Component
No ontology terms assigned.
KEGG Pathways
Metabolic & Signaling
No pathways identified.
Pfam Domains
Protein Families
RINGv

Protein Analysis

237

Amino Acids

25.38

Weight (kDa)

4.84

Isoelectric Point (pI)

45.34

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
RINGv PF12906 111 - 162 1.2e-09 RING-variant domain
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
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Publication-ready
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Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AasI GACNNNNNNGTC 2 cut(s) 86, 260
AatII GACGTC 1 cut(s) 72
AccB7I CCANNNNNTGG 1 cut(s) 271
AccII CGCG 1 cut(s) 104
AccIII TCCGGA 1 cut(s) 374
AciI CCGC 8 cut(s) 27, 46, 75, 104, 147, 174, 290, 499
AclI AACGTT 1 cut(s) 699
AclWI GGATC 1 cut(s) 182
AcyI GRCGYC 2 cut(s) 9, 69
AfaI GTAC 2 cut(s) 155, 164
AfiI CCNNNNNNNGG 3 cut(s) 60, 147, 271
AgsI TTSAA 4 cut(s) 454, 492, 600, 697
AhdI GACNNNNNGTC 1 cut(s) 112
AhlI ACTAGT 1 cut(s) 557
AjnI CCWGG 2 cut(s) 59, 589
AjuI GAANNNNNNNTTGG 2 cut(s) 267, 299
AleI CACNNNNGTG 1 cut(s) 27
AluBI AGCT 3 cut(s) 380, 541, 615
AluI AGCT 3 cut(s) 380, 541, 615
Alw21I GWGCWC 2 cut(s) 24, 382
Alw26I GTCTC 2 cut(s) 231, 599
AlwI GGATC 1 cut(s) 182
AlwNI CAGNNNCTG 1 cut(s) 90
Aor13HI TCCGGA 1 cut(s) 374
AoxI GGCC 4 cut(s) 198, 287, 512, 593
ApeKI GCWGC 4 cut(s) 32, 84, 538, 575
AspS9I GGNCC 4 cut(s) 262, 287, 512, 593
AsuHPI GGTGA 1 cut(s) 89
AvaII GGWCC 1 cut(s) 262
BanII GRGCYC 1 cut(s) 382
Bbv12I GWGCWC 2 cut(s) 24, 382
BbvCI CCTCAGC 2 cut(s) 195, 565
BbvI GCAGC 4 cut(s) 19, 96, 550, 562
BccI CCATC 1 cut(s) 351
BceAI ACGGC 4 cut(s) 40, 97, 160, 588
BcgI CGANNNNNNTGC 2 cut(s) 611, 645
BciT130I CCWGG 2 cut(s) 61, 591
BcoDI GTCTC 2 cut(s) 231, 599
BcuI ACTAGT 1 cut(s) 557
BfaI CTAG 2 cut(s) 231, 558
BfmI CTRYAG 1 cut(s) 576
BglI GCCNNNNNGGC 1 cut(s) 348
BglII AGATCT 1 cut(s) 471
BisI GCNGC 6 cut(s) 33, 85, 174, 290, 539, 576
BlsI GCNGC 6 cut(s) 34, 86, 175, 291, 540, 577
Bme1390I CCNGG 2 cut(s) 61, 591
Bme18I GGWCC 1 cut(s) 262
BmeRI GACNNNNNGTC 1 cut(s) 112
BmgT120I GGNCC 4 cut(s) 262, 287, 512, 593
BmrFI CCNGG 2 cut(s) 61, 591
BmsI GCATC 1 cut(s) 433
BpmI CTGGAG 1 cut(s) 43
Bpu10I CCTNAGC 2 cut(s) 195, 565
BsaHI GRCGYC 2 cut(s) 9, 69
BsaJI CCNNGG 1 cut(s) 590
BsaWI WCCGGW 2 cut(s) 374, 429
BsaXI ACNNNNNCTCC 2 cut(s) 35, 65
Bsc4I CCNNNNNNNGG 3 cut(s) 60, 147, 271
BseAI TCCGGA 1 cut(s) 374
BseBI CCWGG 2 cut(s) 61, 591
BseDI CCNNGG 1 cut(s) 590
BseLI CCNNNNNNNGG 3 cut(s) 60, 147, 271
BseMII CTCAG 3 cut(s) 186, 516, 579
BseXI GCAGC 4 cut(s) 19, 96, 550, 562
Bsh1236I CGCG 1 cut(s) 104
BshFI GGCC 4 cut(s) 200, 289, 514, 595
BsiHKAI GWGCWC 2 cut(s) 24, 382
BsiSI CCGG 5 cut(s) 6, 201, 293, 375, 430
BsiWI CGTACG 1 cut(s) 153
BslI CCNNNNNNNGG 3 cut(s) 60, 147, 271
BsmAI GTCTC 2 cut(s) 231, 599
BsnI GGCC 4 cut(s) 200, 289, 514, 595
Bsp1286I GDGCHC 2 cut(s) 24, 382
Bsp13I TCCGGA 1 cut(s) 374
Bsp143I GATC 4 cut(s) 187, 412, 456, 471
BspACI CCGC 8 cut(s) 27, 46, 75, 104, 147, 174, 290, 499
BspANI GGCC 4 cut(s) 200, 289, 514, 595
BspCNI CTCAG 3 cut(s) 187, 517, 578
BspEI TCCGGA 1 cut(s) 374
BspFNI CGCG 1 cut(s) 104
BspMAI CTGCAG 1 cut(s) 580
BspPI GGATC 1 cut(s) 182
BssECI CCNNGG 1 cut(s) 590
BssMI GATC 4 cut(s) 187, 412, 456, 471
BssNI GRCGYC 2 cut(s) 9, 69
Bst2UI CCWGG 2 cut(s) 61, 591
Bst4CI ACNGT 2 cut(s) 257, 437
BstACI GRCGYC 2 cut(s) 9, 69
BstAPI GCANNNNNTGC 2 cut(s) 90, 575
BstC8I GCNNGC 1 cut(s) 499
BstDEI CTNAG 3 cut(s) 195, 525, 565
BstENI CCTNNNNNAGG 1 cut(s) 58
BstFNI CGCG 1 cut(s) 104
BstKTI GATC 4 cut(s) 190, 415, 459, 474
BstMAI GTCTC 2 cut(s) 231, 599
BstMBI GATC 4 cut(s) 187, 412, 456, 471
BstMWI GCNNNNNNNGC 7 cut(s) 81, 90, 348, 402, 560, 575, 584
BstNI CCWGG 2 cut(s) 61, 591
BstSCI CCNGG 2 cut(s) 59, 589
BstSFI CTRYAG 1 cut(s) 576
BstUI CGCG 1 cut(s) 104
BstV1I GCAGC 4 cut(s) 19, 96, 550, 562
BstX2I RGATCY 1 cut(s) 471
BstYI RGATCY 1 cut(s) 471
BsuRI GGCC 4 cut(s) 200, 289, 514, 595
BtgZI GCGATG 1 cut(s) 614
BtsIMutI CAGTG 1 cut(s) 522
Cac8I GCNNGC 1 cut(s) 499
CaiI CAGNNNCTG 1 cut(s) 90
Cfr13I GGNCC 4 cut(s) 262, 287, 512, 593
CseI GACGC 2 cut(s) 76, 110
Csp6I GTAC 2 cut(s) 154, 163
CviAII CATG 4 cut(s) 266, 368, 623, 681
CviQI GTAC 2 cut(s) 154, 163
DdeI CTNAG 3 cut(s) 195, 525, 565
DpnI GATC 4 cut(s) 189, 414, 458, 473
DpnII GATC 4 cut(s) 187, 412, 456, 471
DrdI GACNNNNNNGTC 2 cut(s) 86, 260
DriI GACNNNNNGTC 1 cut(s) 112
DseDI GACNNNNNNGTC 2 cut(s) 86, 260
Eam1105I GACNNNNNGTC 1 cut(s) 112
Ecl136II GAGCTC 1 cut(s) 380
Eco24I GRGCYC 1 cut(s) 382
Eco47I GGWCC 1 cut(s) 262
Eco53kI GAGCTC 1 cut(s) 380
EcoICRI GAGCTC 1 cut(s) 380
EcoNI CCTNNNNNAGG 1 cut(s) 58
EcoO109I RGGNCCY 1 cut(s) 593
EcoRII CCWGG 2 cut(s) 59, 589
EcoT38I GRGCYC 1 cut(s) 382
FaeI CATG 4 cut(s) 269, 371, 626, 684
FaiI YATR 6 cut(s) 267, 369, 624, 659, 677, 682
FatI CATG 4 cut(s) 265, 367, 622, 680
FauI CCCGC 2 cut(s) 140, 506
Fnu4HI GCNGC 6 cut(s) 33, 85, 174, 290, 539, 576
FriOI GRGCYC 1 cut(s) 382
Fsp4HI GCNGC 6 cut(s) 33, 85, 174, 290, 539, 576
FspBI CTAG 2 cut(s) 231, 558
GluI GCNGC 6 cut(s) 33, 85, 174, 290, 539, 576
GsuI CTGGAG 1 cut(s) 43
HaeIII GGCC 4 cut(s) 200, 289, 514, 595
HapII CCGG 5 cut(s) 6, 201, 293, 375, 430
HgaI GACGC 2 cut(s) 76, 110
Hin1I GRCGYC 2 cut(s) 9, 69
Hin1II CATG 4 cut(s) 269, 371, 626, 684
HindIII AAGCTT 1 cut(s) 613
HinfI GANTC 4 cut(s) 227, 239, 371, 607
HpaII CCGG 5 cut(s) 6, 201, 293, 375, 430
HphI GGTGA 1 cut(s) 89
Hpy188I TCNGA 6 cut(s) 100, 187, 226, 253, 336, 384
Hpy188III TCNNGA 3 cut(s) 375, 454, 708
Hpy99I CGWCG 7 cut(s) 14, 104, 113, 161, 223, 226, 247
HpyAV CCTTC 2 cut(s) 64, 606
HpyCH4III ACNGT 2 cut(s) 257, 437
HpyCH4IV ACGT 2 cut(s) 69, 699
HpyCH4V TGCA 3 cut(s) 307, 405, 578
HpyF10VI GCNNNNNNNGC 7 cut(s) 81, 90, 348, 402, 560, 575, 584
HpyF3I CTNAG 3 cut(s) 195, 525, 565
HpySE526I ACGT 2 cut(s) 69, 699
Hsp92I GRCGYC 2 cut(s) 9, 69
Hsp92II CATG 4 cut(s) 269, 371, 626, 684
Kpn2I TCCGGA 1 cut(s) 374
Kzo9I GATC 4 cut(s) 187, 412, 456, 471
LmnI GCTCC 2 cut(s) 377, 385
Lsp1109I GCAGC 4 cut(s) 19, 96, 550, 562
LweI GCATC 1 cut(s) 433
MaeI CTAG 2 cut(s) 231, 558
MaeII ACGT 2 cut(s) 69, 699
MaeIII GTNAC 3 cut(s) 65, 77, 359
MalI GATC 4 cut(s) 189, 414, 458, 473
MboI GATC 4 cut(s) 187, 412, 456, 471
MboII GAAGA 1 cut(s) 638
MfeI CAATTG 1 cut(s) 492
MflI RGATCY 1 cut(s) 471
MhlI GDGCHC 2 cut(s) 24, 382
MluCI AATT 4 cut(s) 276, 297, 492, 640
MlyI GAGTC 3 cut(s) 233, 236, 601
MmeI TCCRAC 3 cut(s) 123, 204, 314
MnlI CCTC 5 cut(s) 59, 190, 274, 574, 647
MroI TCCGGA 1 cut(s) 374
MseI TTAA 1 cut(s) 300
MslI CAYNNNNRTG 2 cut(s) 27, 527
MspA1I CMGCKG 2 cut(s) 75, 541
MspI CCGG 5 cut(s) 6, 201, 293, 375, 430
MspR9I CCNGG 2 cut(s) 61, 591
MunI CAATTG 1 cut(s) 492
MvaI CCWGG 2 cut(s) 61, 591
MvnI CGCG 1 cut(s) 104
MwoI GCNNNNNNNGC 7 cut(s) 81, 90, 348, 402, 560, 575, 584
NdeII GATC 4 cut(s) 187, 412, 456, 471
NlaIII CATG 4 cut(s) 269, 371, 626, 684
NmuCI GTSAC 2 cut(s) 65, 77
OliI CACNNNNGTG 1 cut(s) 27
PfeI GAWTC 1 cut(s) 371
Pfl23II CGTACG 1 cut(s) 153
PflMI CCANNNNNTGG 1 cut(s) 271
PfoI TCCNGGA 1 cut(s) 59
PkrI GCNGC 6 cut(s) 34, 86, 175, 291, 540, 577
PleI GAGTC 3 cut(s) 233, 235, 601
PpsI GAGTC 3 cut(s) 233, 235, 601
Psp124BI GAGCTC 1 cut(s) 382
Psp1406I AACGTT 1 cut(s) 699
Psp6I CCWGG 2 cut(s) 59, 589
PspGI CCWGG 2 cut(s) 59, 589
PspLI CGTACG 1 cut(s) 153
PspPI GGNCC 4 cut(s) 262, 287, 512, 593
PstI CTGCAG 1 cut(s) 580
PstNI CAGNNNCTG 1 cut(s) 90
PsuI RGATCY 1 cut(s) 471
PvuII CAGCTG 1 cut(s) 541
RsaI GTAC 2 cut(s) 155, 164
RsaNI GTAC 2 cut(s) 154, 163
RseI CAYNNNNRTG 2 cut(s) 27, 527
SacI GAGCTC 1 cut(s) 382
SaqAI TTAA 1 cut(s) 300
SatI GCNGC 6 cut(s) 33, 85, 174, 290, 539, 576
Sau3AI GATC 4 cut(s) 187, 412, 456, 471
Sau96I GGNCC 4 cut(s) 262, 287, 512, 593
SchI GAGTC 3 cut(s) 233, 236, 601
ScrFI CCNGG 2 cut(s) 61, 591
SduI GDGCHC 2 cut(s) 24, 382
SetI ASST 7 cut(s) 72, 285, 306, 382, 543, 617, 702
SfaNI GCATC 1 cut(s) 433
SfcI CTRYAG 1 cut(s) 576
SinI GGWCC 1 cut(s) 262
SmiMI CAYNNNNRTG 2 cut(s) 27, 527
SpeI ACTAGT 1 cut(s) 557
Sse9I AATT 4 cut(s) 276, 297, 492, 640
SsiI CCGC 8 cut(s) 27, 46, 75, 104, 147, 174, 290, 499
SspMI CTAG 2 cut(s) 231, 558
SstI GAGCTC 1 cut(s) 382
StyD4I CCNGG 2 cut(s) 59, 589
TaaI ACNGT 2 cut(s) 257, 437
TaiI ACGT 2 cut(s) 72, 702
TaqI TCGA 2 cut(s) 12, 137
TaqII GACCGA 1 cut(s) 250
TasI AATT 4 cut(s) 276, 297, 492, 640
TatI WGTACW 1 cut(s) 162
TauI GCSGC 2 cut(s) 176, 292
TfiI GAWTC 1 cut(s) 371
Tru1I TTAA 1 cut(s) 300
Tru9I TTAA 1 cut(s) 300
TscAI CASTG 1 cut(s) 529
TseFI GTSAC 2 cut(s) 65, 77
TseI GCWGC 4 cut(s) 32, 84, 538, 575
Tsp45I GTSAC 2 cut(s) 65, 77
TspDTI ATGAA 2 cut(s) 384, 564
TspRI CASTG 1 cut(s) 529
Van91I CCANNNNNTGG 1 cut(s) 271
VpaK11BI GGWCC 1 cut(s) 262
XagI CCTNNNNNAGG 1 cut(s) 58
XspI CTAG 2 cut(s) 231, 558
ZraI GACGTC 1 cut(s) 70
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.