The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins. Some of these proteins have been shown both in vivo and in vitro to have ubiquitin E3 ligase activity.
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| Species | Orthologous Gene IDs |
|---|---|
| fragaria_vesca | FvH4_6g12450 FvH4_6g12450 FvH4_6g12450 FvH4_6g12450 |
| malus_domestica | MD04G1142100.v1.1 MD12G1156700.v1.1 |
| prunus_persica | Prupe.6G267500_v2.0.a1 Prupe.6G267500_v2.0.a1 Prupe.6G267500_v2.0.a1 Prupe.6G267500_v2.0.a1 |
| pyrus_communis | pycom04g12910 pycom12g14890 |
| rosa_chinensis | RchiOBHm_Chr3g0464261 |
| rosa_laevigata | RLG00000024712 |
| rosa_roxburghii | Rroxscaffold_6G00415890 |
| rosa_rugosa | Rorug03G0071200 |
| rosa_samantha | Rh3BG133000 Rh3CG135200 Rh3DG134400 |
| rosa_wichuraiana | Rw3G010880 |
| Enzyme | Recognition Site | Cut Count | Positions (bp) |
|---|---|---|---|
| AasI | GACNNNNNNGTC | 1 cut(s) | 215 |
| AccBSI | CCGCTC | 1 cut(s) | 39 |
| AccI | GTMKAC | 1 cut(s) | 12 |
| AccIII | TCCGGA | 1 cut(s) | 47 |
| AciI | CCGC | 6 cut(s) | 34, 37, 63, 132, 537, 583 |
| AclI | AACGTT | 1 cut(s) | 651 |
| AcuI | CTGAAG | 1 cut(s) | 513 |
| AfaI | GTAC | 2 cut(s) | 149, 511 |
| AfeI | AGCGCT | 1 cut(s) | 55 |
| AfiI | CCNNNNNNNGG | 1 cut(s) | 543 |
| AgsI | TTSAA | 3 cut(s) | 344, 409, 649 |
| AhdI | GACNNNNNGTC | 1 cut(s) | 97 |
| AjnI | CCWGG | 2 cut(s) | 441, 541 |
| AjuI | GAANNNNNNNTTGG | 2 cut(s) | 222, 254 |
| AluBI | AGCT | 1 cut(s) | 527 |
| AluI | AGCT | 1 cut(s) | 527 |
| Alw26I | GTCTC | 1 cut(s) | 165 |
| AlwNI | CAGNNNCTG | 1 cut(s) | 75 |
| Aor13HI | TCCGGA | 1 cut(s) | 47 |
| Aor51HI | AGCGCT | 1 cut(s) | 55 |
| AoxI | GGCC | 3 cut(s) | 26, 467, 545 |
| ApaI | GGGCCC | 1 cut(s) | 30 |
| ApeKI | GCWGC | 3 cut(s) | 69, 374, 377 |
| AspLEI | GCGC | 1 cut(s) | 56 |
| AspS9I | GGNCC | 5 cut(s) | 26, 27, 99, 467, 545 |
| AsuC2I | CCSGG | 2 cut(s) | 187, 331 |
| AsuHPI | GGTGA | 1 cut(s) | 572 |
| AvaII | GGWCC | 1 cut(s) | 99 |
| BaeGI | GKGCMC | 1 cut(s) | 30 |
| BanII | GRGCYC | 2 cut(s) | 30, 337 |
| BbvCI | CCTCAGC | 1 cut(s) | 517 |
| BbvI | GCAGC | 3 cut(s) | 81, 361, 364 |
| BceAI | ACGGC | 2 cut(s) | 76, 532 |
| BciT130I | CCWGG | 2 cut(s) | 443, 543 |
| BcnI | CCSGG | 2 cut(s) | 187, 331 |
| BcoDI | GTCTC | 1 cut(s) | 165 |
| BfoI | RGCGCY | 1 cut(s) | 57 |
| BisI | GCNGC | 6 cut(s) | 37, 70, 133, 375, 378, 537 |
| BlsI | GCNGC | 6 cut(s) | 38, 71, 134, 376, 379, 538 |
| BmcAI | AGTACT | 1 cut(s) | 511 |
| Bme1390I | CCNGG | 4 cut(s) | 187, 331, 443, 543 |
| Bme18I | GGWCC | 1 cut(s) | 99 |
| BmeRI | GACNNNNNGTC | 1 cut(s) | 97 |
| BmgT120I | GGNCC | 5 cut(s) | 26, 27, 99, 467, 545 |
| BmiI | GGNNCC | 5 cut(s) | 28, 29, 100, 136, 336 |
| BmrFI | CCNGG | 4 cut(s) | 187, 331, 443, 543 |
| Bpu10I | CCTNAGC | 1 cut(s) | 517 |
| BpuMI | CCSGG | 2 cut(s) | 187, 331 |
| BsaAI | YACGTR | 1 cut(s) | 402 |
| BsaJI | CCNNGG | 4 cut(s) | 330, 541, 542, 552 |
| BsaWI | WCCGGW | 1 cut(s) | 47 |
| BsaXI | ACNNNNNCTCC | 2 cut(s) | 23, 53 |
| Bsc4I | CCNNNNNNNGG | 1 cut(s) | 543 |
| Bse1I | ACTGG | 1 cut(s) | 507 |
| BseAI | TCCGGA | 1 cut(s) | 47 |
| BseBI | CCWGG | 2 cut(s) | 443, 543 |
| BseDI | CCNNGG | 4 cut(s) | 330, 541, 542, 552 |
| BseGI | GGATG | 1 cut(s) | 370 |
| BseLI | CCNNNNNNNGG | 1 cut(s) | 543 |
| BseMII | CTCAG | 3 cut(s) | 125, 176, 531 |
| BseNI | ACTGG | 1 cut(s) | 507 |
| BseSI | GKGCMC | 1 cut(s) | 30 |
| BseXI | GCAGC | 3 cut(s) | 81, 361, 364 |
| Bsh1285I | CGRYCG | 1 cut(s) | 219 |
| BshFI | GGCC | 3 cut(s) | 28, 469, 547 |
| BsiEI | CGRYCG | 1 cut(s) | 219 |
| BsiSI | CCGG | 4 cut(s) | 48, 187, 248, 330 |
| BslI | CCNNNNNNNGG | 1 cut(s) | 543 |
| BsmAI | GTCTC | 1 cut(s) | 165 |
| BsmBI | CGTCTC | 1 cut(s) | 165 |
| BsnI | GGCC | 3 cut(s) | 28, 469, 547 |
| Bsp120I | GGGCCC | 1 cut(s) | 26 |
| Bsp1286I | GDGCHC | 2 cut(s) | 30, 337 |
| Bsp13I | TCCGGA | 1 cut(s) | 47 |
| Bsp143I | GATC | 1 cut(s) | 165 |
| BspACI | CCGC | 6 cut(s) | 34, 37, 63, 132, 537, 583 |
| BspANI | GGCC | 3 cut(s) | 28, 469, 547 |
| BspCNI | CTCAG | 3 cut(s) | 124, 175, 530 |
| BspEI | TCCGGA | 1 cut(s) | 47 |
| BspLI | GGNNCC | 5 cut(s) | 28, 29, 100, 136, 336 |
| BsrBI | CCGCTC | 1 cut(s) | 39 |
| BsrI | ACTGG | 1 cut(s) | 507 |
| BssECI | CCNNGG | 4 cut(s) | 330, 541, 542, 552 |
| BssMI | GATC | 1 cut(s) | 165 |
| Bst2UI | CCWGG | 2 cut(s) | 443, 543 |
| Bst4CI | ACNGT | 3 cut(s) | 212, 392, 578 |
| BstAPI | GCANNNNNTGC | 1 cut(s) | 75 |
| BstBAI | YACGTR | 1 cut(s) | 402 |
| BstC8I | GCNNGC | 2 cut(s) | 454, 607 |
| BstDEI | CTNAG | 4 cut(s) | 16, 111, 162, 517 |
| BstDSI | CCRYGG | 1 cut(s) | 552 |
| BstEII | GGTNACC | 1 cut(s) | 578 |
| BstF5I | GGATG | 1 cut(s) | 370 |
| BstH2I | RGCGCY | 1 cut(s) | 57 |
| BstHHI | GCGC | 1 cut(s) | 56 |
| BstKTI | GATC | 1 cut(s) | 168 |
| BstMAI | GTCTC | 1 cut(s) | 165 |
| BstMBI | GATC | 1 cut(s) | 165 |
| BstMCI | CGRYCG | 1 cut(s) | 219 |
| BstMWI | GCNNNNNNNGC | 4 cut(s) | 60, 69, 75, 533 |
| BstNI | CCWGG | 2 cut(s) | 443, 543 |
| BstPI | GGTNACC | 1 cut(s) | 578 |
| BstSCI | CCNGG | 4 cut(s) | 185, 329, 441, 541 |
| BstSLI | GKGCMC | 1 cut(s) | 30 |
| BstV1I | GCAGC | 3 cut(s) | 81, 361, 364 |
| BsuRI | GGCC | 3 cut(s) | 28, 469, 547 |
| BtgI | CCRYGG | 1 cut(s) | 552 |
| BtsCI | GGATG | 1 cut(s) | 370 |
| Cac8I | GCNNGC | 2 cut(s) | 454, 607 |
| CaiI | CAGNNNCTG | 1 cut(s) | 75 |
| CfoI | GCGC | 1 cut(s) | 56 |
| Cfr13I | GGNCC | 5 cut(s) | 26, 27, 99, 467, 545 |
| CseI | GACGC | 3 cut(s) | 61, 95, 147 |
| Csp6I | GTAC | 2 cut(s) | 148, 510 |
| CviAII | CATG | 2 cut(s) | 610, 633 |
| CviQI | GTAC | 2 cut(s) | 148, 510 |
| DdeI | CTNAG | 4 cut(s) | 16, 111, 162, 517 |
| DpnI | GATC | 1 cut(s) | 167 |
| DpnII | GATC | 1 cut(s) | 165 |
| DrdI | GACNNNNNNGTC | 1 cut(s) | 215 |
| DriI | GACNNNNNGTC | 1 cut(s) | 97 |
| DseDI | GACNNNNNNGTC | 1 cut(s) | 215 |
| Eam1105I | GACNNNNNGTC | 1 cut(s) | 97 |
| EciI | GGCGGA | 1 cut(s) | 78 |
| Eco24I | GRGCYC | 2 cut(s) | 30, 337 |
| Eco47I | GGWCC | 1 cut(s) | 99 |
| Eco47III | AGCGCT | 1 cut(s) | 55 |
| Eco57I | CTGAAG | 1 cut(s) | 513 |
| Eco91I | GGTNACC | 1 cut(s) | 578 |
| EcoO109I | RGGNCCY | 3 cut(s) | 26, 27, 99 |
| EcoO65I | GGTNACC | 1 cut(s) | 578 |
| EcoRII | CCWGG | 2 cut(s) | 441, 541 |
| EcoT38I | GRGCYC | 2 cut(s) | 30, 337 |
| Esp3I | CGTCTC | 1 cut(s) | 165 |
| FaeI | CATG | 2 cut(s) | 613, 636 |
| FaiI | YATR | 4 cut(s) | 439, 611, 629, 634 |
| FatI | CATG | 2 cut(s) | 609, 632 |
| FblI | GTMKAC | 1 cut(s) | 12 |
| Fnu4HI | GCNGC | 6 cut(s) | 37, 70, 133, 375, 378, 537 |
| FokI | GGATG | 1 cut(s) | 377 |
| FriOI | GRGCYC | 2 cut(s) | 30, 337 |
| Fsp4HI | GCNGC | 6 cut(s) | 37, 70, 133, 375, 378, 537 |
| GlaI | GCGC | 1 cut(s) | 55 |
| GluI | GCNGC | 6 cut(s) | 37, 70, 133, 375, 378, 537 |
| HaeII | RGCGCY | 1 cut(s) | 57 |
| HaeIII | GGCC | 3 cut(s) | 28, 469, 547 |
| HapII | CCGG | 4 cut(s) | 48, 187, 248, 330 |
| HgaI | GACGC | 3 cut(s) | 61, 95, 147 |
| HhaI | GCGC | 1 cut(s) | 56 |
| Hin1II | CATG | 2 cut(s) | 613, 636 |
| Hin6I | GCGC | 1 cut(s) | 54 |
| HinP1I | GCGC | 1 cut(s) | 54 |
| HincII | GTYRAC | 1 cut(s) | 13 |
| HindII | GTYRAC | 1 cut(s) | 13 |
| HinfI | GANTC | 3 cut(s) | 182, 326, 503 |
| HpaII | CCGG | 4 cut(s) | 48, 187, 248, 330 |
| HphI | GGTGA | 1 cut(s) | 572 |
| Hpy166II | GTNNAC | 3 cut(s) | 13, 486, 552 |
| Hpy188I | TCNGA | 6 cut(s) | 85, 165, 181, 208, 291, 339 |
| Hpy188III | TCNNGA | 4 cut(s) | 48, 121, 409, 660 |
| Hpy8I | GTNNAC | 3 cut(s) | 13, 486, 552 |
| Hpy99I | CGWCG | 5 cut(s) | 89, 98, 146, 464, 661 |
| HpyAV | CCTTC | 2 cut(s) | 52, 608 |
| HpyCH4III | ACNGT | 3 cut(s) | 212, 392, 578 |
| HpyCH4IV | ACGT | 3 cut(s) | 401, 459, 651 |
| HpyCH4V | TGCA | 4 cut(s) | 262, 360, 452, 609 |
| HpyF10VI | GCNNNNNNNGC | 4 cut(s) | 60, 69, 75, 533 |
| HpyF3I | CTNAG | 4 cut(s) | 16, 111, 162, 517 |
| HpySE526I | ACGT | 3 cut(s) | 401, 459, 651 |
| Hsp92II | CATG | 2 cut(s) | 613, 636 |
| HspAI | GCGC | 1 cut(s) | 54 |
| Kpn2I | TCCGGA | 1 cut(s) | 47 |
| Kzo9I | GATC | 1 cut(s) | 165 |
| LmnI | GCTCC | 3 cut(s) | 44, 140, 340 |
| Lsp1109I | GCAGC | 3 cut(s) | 81, 361, 364 |
| MaeII | ACGT | 3 cut(s) | 401, 459, 651 |
| MaeIII | GTNAC | 3 cut(s) | 104, 314, 578 |
| MalI | GATC | 1 cut(s) | 167 |
| MbiI | CCGCTC | 1 cut(s) | 39 |
| MboI | GATC | 1 cut(s) | 165 |
| MboII | GAAGA | 1 cut(s) | 109 |
| MhlI | GDGCHC | 2 cut(s) | 30, 337 |
| MluCI | AATT | 4 cut(s) | 151, 231, 252, 344 |
| MmeI | TCCRAC | 3 cut(s) | 108, 159, 269 |
| MnlI | CCTC | 4 cut(s) | 205, 214, 526, 599 |
| MroI | TCCGGA | 1 cut(s) | 47 |
| MseI | TTAA | 2 cut(s) | 255, 414 |
| MspI | CCGG | 4 cut(s) | 48, 187, 248, 330 |
| MspR9I | CCNGG | 4 cut(s) | 187, 331, 443, 543 |
| MvaI | CCWGG | 2 cut(s) | 443, 543 |
| MwoI | GCNNNNNNNGC | 4 cut(s) | 60, 69, 75, 533 |
| NciI | CCSGG | 2 cut(s) | 187, 331 |
| NdeII | GATC | 1 cut(s) | 165 |
| NlaIII | CATG | 2 cut(s) | 613, 636 |
| NlaIV | GGNNCC | 5 cut(s) | 28, 29, 100, 136, 336 |
| NmuCI | GTSAC | 1 cut(s) | 578 |
| PasI | CCCWGGG | 1 cut(s) | 542 |
| PcsI | WCGNNNNNNNCGW | 1 cut(s) | 225 |
| PfeI | GAWTC | 3 cut(s) | 182, 326, 503 |
| PfoI | TCCNGGA | 1 cut(s) | 185 |
| PkrI | GCNGC | 6 cut(s) | 38, 71, 134, 376, 379, 538 |
| Ppu21I | YACGTR | 1 cut(s) | 402 |
| PpuMI | RGGWCCY | 1 cut(s) | 99 |
| Psp1406I | AACGTT | 1 cut(s) | 651 |
| Psp5II | RGGWCCY | 1 cut(s) | 99 |
| Psp6I | CCWGG | 2 cut(s) | 441, 541 |
| PspEI | GGTNACC | 1 cut(s) | 578 |
| PspGI | CCWGG | 2 cut(s) | 441, 541 |
| PspN4I | GGNNCC | 5 cut(s) | 28, 29, 100, 136, 336 |
| PspOMI | GGGCCC | 1 cut(s) | 26 |
| PspPI | GGNCC | 5 cut(s) | 26, 27, 99, 467, 545 |
| PspPPI | RGGWCCY | 1 cut(s) | 99 |
| PstNI | CAGNNNCTG | 1 cut(s) | 75 |
| RsaI | GTAC | 2 cut(s) | 149, 511 |
| RsaNI | GTAC | 2 cut(s) | 148, 510 |
| SalI | GTCGAC | 1 cut(s) | 11 |
| SaqAI | TTAA | 2 cut(s) | 255, 414 |
| SatI | GCNGC | 6 cut(s) | 37, 70, 133, 375, 378, 537 |
| Sau3AI | GATC | 1 cut(s) | 165 |
| Sau96I | GGNCC | 5 cut(s) | 26, 27, 99, 467, 545 |
| ScaI | AGTACT | 1 cut(s) | 511 |
| ScrFI | CCNGG | 4 cut(s) | 187, 331, 443, 543 |
| SduI | GDGCHC | 2 cut(s) | 30, 337 |
| SetI | ASST | 7 cut(s) | 225, 261, 404, 431, 462, 529, 654 |
| SinI | GGWCC | 1 cut(s) | 99 |
| Sse9I | AATT | 4 cut(s) | 151, 231, 252, 344 |
| SsiI | CCGC | 6 cut(s) | 34, 37, 63, 132, 537, 583 |
| StyD4I | CCNGG | 4 cut(s) | 185, 329, 441, 541 |
| TaaI | ACNGT | 3 cut(s) | 212, 392, 578 |
| TaiI | ACGT | 3 cut(s) | 404, 462, 654 |
| TaqI | TCGA | 5 cut(s) | 12, 122, 219, 228, 497 |
| TaqII | GACCGA | 1 cut(s) | 205 |
| TasI | AATT | 4 cut(s) | 151, 231, 252, 344 |
| TatI | WGTACW | 2 cut(s) | 147, 509 |
| TauI | GCSGC | 3 cut(s) | 39, 135, 539 |
| TfiI | GAWTC | 3 cut(s) | 182, 326, 503 |
| Tru1I | TTAA | 2 cut(s) | 255, 414 |
| Tru9I | TTAA | 2 cut(s) | 255, 414 |
| TseFI | GTSAC | 1 cut(s) | 578 |
| TseI | GCWGC | 3 cut(s) | 69, 374, 377 |
| Tsp45I | GTSAC | 1 cut(s) | 578 |
| TspGWI | ACGGA | 2 cut(s) | 569, 645 |
| VpaK11BI | GGWCC | 1 cut(s) | 99 |
| XmiI | GTMKAC | 1 cut(s) | 12 |
| ZrmI | AGTACT | 1 cut(s) | 511 |