pycom03g13540

NAD-dependent protein deacetylase

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
pyrus_communis
Chr3
OG0013314
Physical Location & Seq
Forward (+)
14618064 .. 14626171
8108 bp
Loading structure...
UTR
Exon/CDS
Intron
N/A

Sequence Viewer

Length: 1587 bp
ATGTCATATATCTGGGCCTCTCACTCTCCACCTTTTGATCAAAACTTTCACACAGAGGGGGGAGAGAGAGAGAGAGGTACAGGGCGAAGGTGGTATACGAAGCATCAGAGTGACCATGTCCTTGGGTTATGCAGAGAAGCTTTCCTACATAGAAGATGTGGGCCAAGTCGGAATGACAGAACATTTCGACATGCCTCAAGTTTTGCAAGAAAAATTGAAATTGAGCGGCTCGCCATGTTGGTGCAAAAGAGTAAGCATCTGGTGGTGTTTACAGGTGCAGGAATCTCAACCTCTTGTGGTATACCTGATTTTCGAGGTCCAAAGGGAATTTGGACTCTGCAGCGTGAAGGCAAAGCCTTGCCTGAAGCATCATTGCCATTTCATCGTGCAATGCCTAGCTTGACTCATATGGCTTTGGTTGAACTGGAGAGAGCTGGAATTTTGAAGTTTGTAATTAGCCAGAATGTTGATGGTCTTCATCTTCGATCTGGAATACCAAGGGAGAAACTTGCCGAGTTACATGGTAACTCCTTTCTGGAAACCTGCCCTTCTTGTGGAGTCGAATATTTGAGGGATTTTGAGGTTGAGACTATTGGACTGAAGGAGACTTCAAGACGGTGCTCAGATGAAAATTGTAGAGCAAGGCTTAAGGATACAGTTCTTGACTGGGAGGATGCATTGCCCTCAAAGGAGATGGATCTGGCTGAGAAGCACTGCAGGATGGCTGATGTTGTATTATGTTTGGGGACAAGTTTGCAGATCACTCCAGCATGCAATCTTCCTCTGAAATCGCTCCGTGGTGGAGGAAAGATTGTAATTGTCAACCTTCAGAAAACTCCAAAGGACAAGAAAGCAAATTTAGTGATCCATGGACTCGTTGATAAGGTTATTTCAGGTGTCATGGACTTTCTGAATCTTCAGATTCCTCCATTTGTCCGGATAGATCATGTTCAGATCATTCTAACTCAAGCCTTGAGTTTAGATAAAAAGAATGTGAACTGGAGCCTCCGCGTCACAAGTATACATGGACAGAAAGCTCCATTGCCATTTATCAAATCCATTGAGATATCCTTCTTAGACAATCAAGGGTATAAATCAGCTATTCTACAGAAGGAACCATTTCAATTGAAAAGGAGAACCTTGCAGGGAAAATCGTTTGATATGGTTTTGAAAATCAACTTTATAGATAGTTGTGGTTGTCTATCCACAGAAATTGTTGTGCCTCTTAATCTTAAGGTTCCAGAAGATAGTCTTCAGCTTGATAAGGATGCCATATTGCAAAAGCTCAGACACACGGCAGTTCAAGAATCATGCTGTGGACAGAATGCAATTGTTGAGAGAAATGTCATCCTGGCCCCAAAGACTGAGGTCATTGCACATGCCATTGTAACGAATGTTGTCCGGTATAGGATGACTGCTGAAGCCTTGCAAGCTGGTTCCCTAGGACTGACGAAAAGCATGATTAGTAGGAACTGGGTGAATTTTGTTAGATGCTGCACCTCAGTCTCCCCAGCTATGAACAGCCCTTGTTATAACTTAATCGGCAAATATGATAATCAAAATCATGGCCTTTGGTTGCTTCTGTAA
Functional Annotation
Gene Ontology
Molecular Function
Biological Process
Cellular Component
No ontology terms assigned.
KEGG Pathways
Metabolic & Signaling
ko04714 ko05230 map04714 map05230
Pfam Domains
Protein Families
SIR2

Protein Analysis

529

Amino Acids

59.23

Weight (kDa)

9.15

Isoelectric Point (pI)

44.34

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
SIR2 PF02146 127 - 256 3.2e-20 Sir2 family
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
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Publication-ready
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Orthologous Genes (Group: OG0013314)

Species Orthologous Gene IDs
arabidopsis_thaliana AT5G55760
fragaria_vesca FvH4_3g29170 FvH4_3g29170
malus_domestica MD03G1179400.v1.1 MD11G1199100.v1.1
prunus_persica Prupe.4G243700_v2.0.a1 Prupe.4G243700_v2.0.a1
pyrus_communis pycom03g13540 pycom11g17170
rosa_chinensis RchiOBHm_Chr5g0053471
rosa_laevigata RLG00000034885
rosa_roxburghii Rroxscaffold_1G00026940
rosa_rugosa Rorug05G0280200
rosa_samantha Rh5AG351400 Rh5BG363600 Rh5DG378300 Rh7BG051900
rosa_wichuraiana Rw5G033230

Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AanI TTATAA 1 cut(s) 1533
Acc36I ACCTGC 1 cut(s) 551
AccBSI CCGCTC 1 cut(s) 226
AccI GTMKAC 3 cut(s) 95, 301, 1021
AccII CGCG 1 cut(s) 1011
AccIII TCCGGA 1 cut(s) 936
AciI CCGC 2 cut(s) 226, 1009
AclWI GGATC 2 cut(s) 705, 859
AcsI RAATTY 4 cut(s) 327, 438, 856, 1480
AcuI CTGAAG 6 cut(s) 384, 620, 812, 902, 1238, 1440
AfaI GTAC 1 cut(s) 79
AfiI CCNNNNNNNGG 1 cut(s) 554
AflII CTTAAG 2 cut(s) 647, 1232
AgsI TTSAA 8 cut(s) 218, 422, 445, 612, 1124, 1129, 1171, 1304
AjnI CCWGG 1 cut(s) 1350
AluBI AGCT 9 cut(s) 140, 399, 434, 1037, 1100, 1258, 1285, 1433, 1514
AluI AGCT 9 cut(s) 140, 399, 434, 1037, 1100, 1258, 1285, 1433, 1514
Alw21I GWGCWC 1 cut(s) 623
Alw26I GTCTC 3 cut(s) 581, 599, 1510
AlwI GGATC 2 cut(s) 705, 859
Aor13HI TCCGGA 1 cut(s) 936
AoxI GGCC 4 cut(s) 15, 161, 1353, 1567
ApeKI GCWGC 2 cut(s) 340, 1494
ApoI RAATTY 4 cut(s) 327, 438, 856, 1480
Asp700I GAANNNNTTC 1 cut(s) 1119
AspA2I CCTAGG 1 cut(s) 1441
AspS9I GGNCC 4 cut(s) 15, 161, 317, 1354
AsuHPI GGTGA 1 cut(s) 1489
AvaII GGWCC 1 cut(s) 317
AvrII CCTAGG 1 cut(s) 1441
BarI GAAGNNNNNNTAC 4 cut(s) 79, 111, 129, 161
BbsI GAAGAC 2 cut(s) 467, 1244
Bbv12I GWGCWC 1 cut(s) 623
BbvI GCAGC 2 cut(s) 352, 1481
BccI CCATC 3 cut(s) 464, 688, 715
BceAI ACGGC 1 cut(s) 1311
BciT130I CCWGG 1 cut(s) 1352
BciVI GTATCC 1 cut(s) 646
BclI TGATCA 1 cut(s) 37
BcoDI GTCTC 3 cut(s) 581, 599, 1510
BfaI CTAG 2 cut(s) 396, 1442
BfmI CTRYAG 3 cut(s) 338, 715, 1106
BfrI CTTAAG 2 cut(s) 647, 1232
BfuAI ACCTGC 1 cut(s) 551
BfuI GTATCC 1 cut(s) 646
BisI GCNGC 3 cut(s) 227, 341, 1495
BlnI CCTAGG 1 cut(s) 1441
BlsI GCNGC 3 cut(s) 228, 342, 1496
Bme1390I CCNGG 1 cut(s) 1352
Bme18I GGWCC 1 cut(s) 317
BmgT120I GGNCC 4 cut(s) 15, 161, 317, 1354
BmiI GGNNCC 5 cut(s) 1004, 1116, 1239, 1356, 1438
BmrFI CCNGG 1 cut(s) 1352
BmrI ACTGGG 2 cut(s) 676, 1483
BmsI GCATC 6 cut(s) 112, 265, 377, 664, 1258, 1481
BmuI ACTGGG 2 cut(s) 676, 1483
BoxI GACNNNNGTC 1 cut(s) 1367
BpiI GAAGAC 2 cut(s) 467, 1244
BpmI CTGGAG 3 cut(s) 446, 750, 1021
BpuEI CTTGAG 3 cut(s) 181, 951, 994
BsaJI CCNNGG 5 cut(s) 121, 497, 796, 868, 1441
BsaWI WCCGGW 2 cut(s) 936, 1401
Bsc4I CCNNNNNNNGG 1 cut(s) 554
Bse1I ACTGG 4 cut(s) 429, 671, 1004, 1478
Bse3DI GCAATG 5 cut(s) 371, 396, 677, 1040, 1371
BseAI TCCGGA 1 cut(s) 936
BseBI CCWGG 1 cut(s) 1352
BseDI CCNNGG 5 cut(s) 121, 497, 796, 868, 1441
BseGI GGATG 5 cut(s) 679, 726, 1273, 1347, 1416
BseLI CCNNNNNNNGG 1 cut(s) 554
BseMI GCAATG 5 cut(s) 371, 396, 677, 1040, 1371
BseMII CTCAG 5 cut(s) 636, 696, 1300, 1356, 1515
BseNI ACTGG 4 cut(s) 429, 671, 1004, 1478
BseXI GCAGC 2 cut(s) 352, 1481
BseYI CCCAGC 1 cut(s) 1510
BsgI GTGCAG 2 cut(s) 297, 1480
Bsh1236I CGCG 1 cut(s) 1011
BshFI GGCC 4 cut(s) 17, 163, 1355, 1569
BsiHKAI GWGCWC 1 cut(s) 623
BsiSI CCGG 2 cut(s) 937, 1402
BslFI GGGAC 1 cut(s) 760
BslI CCNNNNNNNGG 1 cut(s) 554
BsmAI GTCTC 3 cut(s) 581, 599, 1510
BsmFI GGGAC 1 cut(s) 760
BsmI GAATGC 1 cut(s) 1330
BsnI GGCC 4 cut(s) 17, 163, 1355, 1569
Bsp1286I GDGCHC 1 cut(s) 623
Bsp13I TCCGGA 1 cut(s) 936
Bsp143I GATC 7 cut(s) 37, 485, 697, 759, 864, 943, 954
Bsp19I CCATGG 1 cut(s) 868
BspACI CCGC 2 cut(s) 226, 1009
BspANI GGCC 4 cut(s) 17, 163, 1355, 1569
BspCNI CTCAG 5 cut(s) 635, 697, 1299, 1357, 1514
BspEI TCCGGA 1 cut(s) 936
BspFNI CGCG 1 cut(s) 1011
BspLI GGNNCC 5 cut(s) 1004, 1116, 1239, 1356, 1438
BspMAI CTGCAG 2 cut(s) 342, 719
BspMI ACCTGC 1 cut(s) 551
BspPI GGATC 2 cut(s) 705, 859
BspTI CTTAAG 2 cut(s) 647, 1232
BsrBI CCGCTC 1 cut(s) 226
BsrDI GCAATG 5 cut(s) 371, 396, 677, 1040, 1371
BsrI ACTGG 4 cut(s) 429, 671, 1004, 1478
BssECI CCNNGG 5 cut(s) 121, 497, 796, 868, 1441
BssMI GATC 7 cut(s) 37, 485, 697, 759, 864, 943, 954
BssNAI GTATAC 3 cut(s) 96, 302, 1022
BssT1I CCWWGG 4 cut(s) 121, 497, 868, 1441
Bst1107I GTATAC 3 cut(s) 96, 302, 1022
Bst2UI CCWGG 1 cut(s) 1352
Bst4CI ACNGT 2 cut(s) 618, 658
BstAFI CTTAAG 2 cut(s) 647, 1232
BstC8I GCNNGC 3 cut(s) 231, 772, 1431
BstDEI CTNAG 6 cut(s) 622, 705, 1075, 1286, 1365, 1501
BstDSI CCRYGG 2 cut(s) 796, 868
BstF5I GGATG 5 cut(s) 679, 726, 1273, 1347, 1416
BstFNI CGCG 1 cut(s) 1011
BstKTI GATC 7 cut(s) 40, 488, 700, 762, 867, 946, 957
BstMAI GTCTC 3 cut(s) 581, 599, 1510
BstMBI GATC 7 cut(s) 37, 485, 697, 759, 864, 943, 954
BstMWI GCNNNNNNNGC 1 cut(s) 1430
BstNI CCWGG 1 cut(s) 1352
BstNSI RCATGY 3 cut(s) 194, 774, 1382
BstPAI GACNNNNGTC 1 cut(s) 1367
BstSCI CCNGG 1 cut(s) 1350
BstSFI CTRYAG 3 cut(s) 338, 715, 1106
BstUI CGCG 1 cut(s) 1011
BstV1I GCAGC 2 cut(s) 352, 1481
BstV2I GAAGAC 2 cut(s) 467, 1244
BstX2I RGATCY 1 cut(s) 697
BstXI CCANNNNNNTGG 1 cut(s) 122
BstYI RGATCY 1 cut(s) 697
BstZ17I GTATAC 3 cut(s) 96, 302, 1022
BsuI GTATCC 1 cut(s) 646
BsuRI GGCC 4 cut(s) 17, 163, 1355, 1569
BtgI CCRYGG 2 cut(s) 796, 868
BtsCI GGATG 5 cut(s) 679, 726, 1273, 1347, 1416
BtsI GCAGTG 1 cut(s) 712
BtsIMutI CAGTG 1 cut(s) 712
BveI ACCTGC 1 cut(s) 551
Cac8I GCNNGC 3 cut(s) 231, 772, 1431
Cfr13I GGNCC 4 cut(s) 15, 161, 317, 1354
CseI GACGC 1 cut(s) 1000
Csp6I GTAC 1 cut(s) 78
CspCI CAANNNNNGTGG 2 cut(s) 1195, 1230
CviQI GTAC 1 cut(s) 78
DdeI CTNAG 6 cut(s) 622, 705, 1075, 1286, 1365, 1501
DpnI GATC 7 cut(s) 39, 487, 699, 761, 866, 945, 956
DpnII GATC 7 cut(s) 37, 485, 697, 759, 864, 943, 954
Eco130I CCWWGG 4 cut(s) 121, 497, 868, 1441
Eco32I GATATC 1 cut(s) 1068
Eco47I GGWCC 1 cut(s) 317
Eco57I CTGAAG 6 cut(s) 384, 620, 812, 902, 1238, 1440
EcoRII CCWGG 1 cut(s) 1350
EcoRV GATATC 1 cut(s) 1068
EcoT14I CCWWGG 4 cut(s) 121, 497, 868, 1441
EcoT22I ATGCAT 1 cut(s) 679
ErhI CCWWGG 4 cut(s) 121, 497, 868, 1441
FalI AAGNNNNNCTT 2 cut(s) 1236, 1268
FaqI GGGAC 1 cut(s) 760
FauNDI CATATG 1 cut(s) 408
FbaI TGATCA 1 cut(s) 37
FblI GTMKAC 3 cut(s) 95, 301, 1021
Fnu4HI GCNGC 3 cut(s) 227, 341, 1495
FokI GGATG 5 cut(s) 686, 733, 1280, 1334, 1423
Fsp4HI GCNGC 3 cut(s) 227, 341, 1495
FspBI CTAG 2 cut(s) 396, 1442
GluI GCNGC 3 cut(s) 227, 341, 1495
GsaI CCCAGC 1 cut(s) 1514
GsuI CTGGAG 3 cut(s) 446, 750, 1021
HaeIII GGCC 4 cut(s) 17, 163, 1355, 1569
HapII CCGG 2 cut(s) 937, 1402
HgaI GACGC 1 cut(s) 1000
HincII GTYRAC 1 cut(s) 823
HindII GTYRAC 1 cut(s) 823
HindIII AAGCTT 1 cut(s) 138
HinfI GANTC 8 cut(s) 282, 334, 403, 558, 873, 913, 922, 1307
HpaII CCGG 2 cut(s) 937, 1402
HphI GGTGA 1 cut(s) 1489
Hpy166II GTNNAC 7 cut(s) 96, 270, 302, 823, 997, 1022, 1319
Hpy188I TCNGA 9 cut(s) 108, 171, 625, 786, 831, 912, 921, 954, 1289
Hpy188III TCNNGA 7 cut(s) 489, 536, 612, 662, 937, 1241, 1304
Hpy8I GTNNAC 7 cut(s) 96, 270, 302, 823, 997, 1022, 1319
HpyAV CCTTC 7 cut(s) 81, 341, 558, 595, 836, 1081, 1105
HpyCH4III ACNGT 2 cut(s) 618, 658
HpyF10VI GCNNNNNNNGC 1 cut(s) 1430
HpyF3I CTNAG 6 cut(s) 622, 705, 1075, 1286, 1365, 1501
Kpn2I TCCGGA 1 cut(s) 936
Ksp22I TGATCA 1 cut(s) 37
Kzo9I GATC 7 cut(s) 37, 485, 697, 759, 864, 943, 954
LmnI GCTCC 3 cut(s) 798, 1002, 1042
Lsp1109I GCAGC 2 cut(s) 352, 1481
LweI GCATC 6 cut(s) 112, 265, 377, 664, 1258, 1481
MaeI CTAG 2 cut(s) 396, 1442
MaeIII GTNAC 5 cut(s) 110, 516, 524, 1012, 1387
MalI GATC 7 cut(s) 39, 487, 699, 761, 866, 945, 956
MbiI CCGCTC 1 cut(s) 226
MboI GATC 7 cut(s) 37, 485, 697, 759, 864, 943, 954
MboII GAAGA 7 cut(s) 165, 467, 473, 770, 908, 1244, 1256
MfeI CAATTG 2 cut(s) 1124, 1329
MflI RGATCY 1 cut(s) 697
MhlI GDGCHC 1 cut(s) 623
MlyI GAGTC 4 cut(s) 328, 397, 567, 867
MmeI TCCRAC 1 cut(s) 149
Mph1103I ATGCAT 1 cut(s) 679
MroI TCCGGA 1 cut(s) 936
MroXI GAANNNNTTC 1 cut(s) 1119
MseI TTAA 4 cut(s) 648, 1227, 1233, 1538
MslI CAYNNNNRTG 2 cut(s) 108, 239
MspCI CTTAAG 2 cut(s) 647, 1232
MspI CCGG 2 cut(s) 937, 1402
MspR9I CCNGG 1 cut(s) 1352
MunI CAATTG 2 cut(s) 1124, 1329
Mva1269I GAATGC 1 cut(s) 1330
MvaI CCWGG 1 cut(s) 1352
MvnI CGCG 1 cut(s) 1011
MwoI GCNNNNNNNGC 1 cut(s) 1430
NcoI CCATGG 1 cut(s) 868
NdeI CATATG 1 cut(s) 408
NdeII GATC 7 cut(s) 37, 485, 697, 759, 864, 943, 954
NlaIV GGNNCC 5 cut(s) 1004, 1116, 1239, 1356, 1438
NmeAIII GCCGAG 1 cut(s) 538
NmuCI GTSAC 2 cut(s) 110, 1012
NsiI ATGCAT 1 cut(s) 679
NspI RCATGY 3 cut(s) 194, 774, 1382
PaeI GCATGC 1 cut(s) 774
PctI GAATGC 1 cut(s) 1330
PdmI GAANNNNTTC 1 cut(s) 1119
PfeI GAWTC 4 cut(s) 282, 913, 922, 1307
PflFI GACNNNGTC 1 cut(s) 116
PkrI GCNGC 3 cut(s) 228, 342, 1496
PleI GAGTC 4 cut(s) 328, 397, 566, 867
PpsI GAGTC 4 cut(s) 328, 397, 566, 867
PshAI GACNNNNGTC 1 cut(s) 1367
PsiI TTATAA 1 cut(s) 1533
Psp6I CCWGG 1 cut(s) 1350
PspFI CCCAGC 1 cut(s) 1510
PspGI CCWGG 1 cut(s) 1350
PspN4I GGNNCC 5 cut(s) 1004, 1116, 1239, 1356, 1438
PspPI GGNCC 4 cut(s) 15, 161, 317, 1354
PstI CTGCAG 2 cut(s) 342, 719
PsuI RGATCY 1 cut(s) 697
PsyI GACNNNGTC 1 cut(s) 116
RsaI GTAC 1 cut(s) 79
RsaNI GTAC 1 cut(s) 78
RseI CAYNNNNRTG 2 cut(s) 108, 239
SaqAI TTAA 4 cut(s) 648, 1227, 1233, 1538
SatI GCNGC 3 cut(s) 227, 341, 1495
Sau3AI GATC 7 cut(s) 37, 485, 697, 759, 864, 943, 954
Sau96I GGNCC 4 cut(s) 15, 161, 317, 1354
SchI GAGTC 4 cut(s) 328, 397, 567, 867
ScrFI CCNGG 1 cut(s) 1352
SduI GDGCHC 1 cut(s) 623
SfaNI GCATC 6 cut(s) 112, 265, 377, 664, 1258, 1481
SfcI CTRYAG 3 cut(s) 338, 715, 1106
SinI GGWCC 1 cut(s) 317
SmiMI CAYNNNNRTG 2 cut(s) 108, 239
SmlI CTYRAG 5 cut(s) 196, 647, 966, 973, 1232
SmoI CTYRAG 5 cut(s) 196, 647, 966, 973, 1232
SphI GCATGC 1 cut(s) 774
SsiI CCGC 2 cut(s) 226, 1009
SspI AATATT 1 cut(s) 566
SspMI CTAG 2 cut(s) 396, 1442
StyD4I CCNGG 1 cut(s) 1350
StyI CCWWGG 4 cut(s) 121, 497, 868, 1441
TaaI ACNGT 2 cut(s) 618, 658
TaqI TCGA 4 cut(s) 187, 313, 484, 561
TauI GCSGC 1 cut(s) 229
TfiI GAWTC 4 cut(s) 282, 913, 922, 1307
Tru1I TTAA 4 cut(s) 648, 1227, 1233, 1538
Tru9I TTAA 4 cut(s) 648, 1227, 1233, 1538
TscAI CASTG 1 cut(s) 719
TseFI GTSAC 2 cut(s) 110, 1012
TseI GCWGC 2 cut(s) 340, 1494
Tsp45I GTSAC 2 cut(s) 110, 1012
TspDTI ATGAA 4 cut(s) 371, 467, 642, 1532
TspGWI ACGGA 1 cut(s) 785
TspRI CASTG 1 cut(s) 719
Tth111I GACNNNGTC 1 cut(s) 116
Vha464I CTTAAG 2 cut(s) 647, 1232
VpaK11BI GGWCC 1 cut(s) 317
XapI RAATTY 4 cut(s) 327, 438, 856, 1480
XceI RCATGY 3 cut(s) 194, 774, 1382
XcmI CCANNNNNNNNNTGG 2 cut(s) 327, 467
XmaJI CCTAGG 1 cut(s) 1441
XmiI GTMKAC 3 cut(s) 95, 301, 1021
XmnI GAANNNNTTC 1 cut(s) 1119
XspI CTAG 2 cut(s) 396, 1442
Zsp2I ATGCAT 1 cut(s) 679
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.