pycom11g17170

NAD-dependent protein deacetylase

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
pyrus_communis
Chr11
OG0013314
Physical Location & Seq
Reverse (-)
19212475 .. 19219442
6968 bp
Loading structure...
UTR
Exon/CDS
Intron
N/A

Sequence Viewer

Length: 1425 bp
ATGTCCTTGGGTTATGCAGAGAAGCTTTCCTACATAGAAGATGTGGGCCAAGTCGGAATGACAGAACATTTCGACGCGCCTCAAGTTTTGCAAGAAAAAATTGAGCGGCTTGCTATGTTGATACAAAAGAGTAAGCATCTAGTAGTGTTTACAGGTGCAGGAATCTCGACTTCTTGTGGTATACCTGACTTTCGAGGTCCAAAGGGAATTTGGACTCTGCAGCGTGAAGGCAAGGCTTTGCCAGAAGCATCATTGCCATTTCATCGTGCAATGCCGAGCTTGACTCATATAGCTTTGGTTGAACTGGAGAGAGCTGGAATTTTGAAGTTTGTAATTAGCCAGAATGTTGATGGTCTTCATCTTCGATCTGGAATACCGAGGGAGAAACTTGCTGAGTTACATGGTAACTCCTTTCTGGAAACCTGCCCTTCTTGTGGAGTCGAGTATTTGAGGGATTTTGAGGTTGAGACTATTGGACTGAAGGAGACTTCAAGACGGTGCTCAGATGAAAATTGTAGAGCAAGGCTTAAAGATACAGTTCTGGATTGGGAGGATGCATTGCCCTCAAAGGAGATGGATCTGGCTGAGAAGCACTGCAGGATGGCGGATGTTGTATTATGTTTGGGGACAAGTTTGCAGATCACTCCAGCGTGCAACCTTCCTCTGAAATCGCTCCGTGGTGGGGGAAAGATTGTAATTGTCAACCTTCAGAAAACTCCAAAGGACAAGAAAGCAAATTTAGTGATCCATGGACTTGTTGATAAGGTTATTTCAGGTGTCATGGACTTTCTAAATCTTCAGATTCCTCCATTTGTCCGGATAGATCTTTTTCAGATCATTCTAACTCAAGCCTTGAGTTTAGATAAAAAGAATGTGAACTGGAGCCTCCGCGTAGCAAGTGTACATGGACAGAAAGCTCCATTGCCATTTGTCAAATCTATTGAGATATCCTTCTTAGACAATCAAGGGTATAAATCAGCTATTCTACAGAAGGAACCATTTCAATTGAAAAGGAGAACCTTGCAGGGAAAATCATTTGATATGGTTTTGAAATTCAACTTCATAGATAGTTGTGGTTGTCCGTCCACAGAAATTGTTGTACCTCTTAATTTTAAGGTTCCAGAAGACTGTCTTACGCTTGATAAGGATTCAGTATTGCAAAAGCTGAGACACACAGCAATTCAAGAATCATGCTGTGGGCAGAATGCAATTGTTGAGAGAAATGTCATCCTGACCCCAAAAACTAAGGTCATTGCATATGCCATTGTAACAAATGTTGTCCGGTATAGGATGACTGCTGAAGCCTTGCAAGCTGGTTCCCTAGGTAATGCCATTAAAAGGCGAAAAGGAAGTGTCAATGGTTTTGAAACATCAAGGAAGATCGATCAAAAGTGCACAGGCGCAAATCTAGATTTTAGAAACTGA
Functional Annotation
Gene Ontology
Molecular Function
Biological Process
Cellular Component
No ontology terms assigned.
KEGG Pathways
Metabolic & Signaling
ko04714 ko05230 map04714 map05230
Pfam Domains
Protein Families
SIR2

Protein Analysis

475

Amino Acids

52.69

Weight (kDa)

8.94

Isoelectric Point (pI)

40.4

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
SIR2 PF02146 87 - 216 4.5e-20 Sir2 family
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
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Publication-ready
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Orthologous Genes (Group: OG0013314)

Species Orthologous Gene IDs
arabidopsis_thaliana AT5G55760
fragaria_vesca FvH4_3g29170 FvH4_3g29170
malus_domestica MD03G1179400.v1.1 MD11G1199100.v1.1
prunus_persica Prupe.4G243700_v2.0.a1 Prupe.4G243700_v2.0.a1
pyrus_communis pycom03g13540 pycom11g17170
rosa_chinensis RchiOBHm_Chr5g0053471
rosa_laevigata RLG00000034885
rosa_roxburghii Rroxscaffold_1G00026940
rosa_rugosa Rorug05G0280200
rosa_samantha Rh5AG351400 Rh5BG363600 Rh5DG378300 Rh7BG051900
rosa_wichuraiana Rw5G033230

Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
Acc36I ACCTGC 1 cut(s) 431
AccBSI CCGCTC 1 cut(s) 106
AccI GTMKAC 1 cut(s) 181
AccII CGCG 2 cut(s) 77, 891
AccIII TCCGGA 1 cut(s) 816
AciI CCGC 3 cut(s) 106, 605, 889
AclWI GGATC 2 cut(s) 585, 739
AcsI RAATTY 4 cut(s) 207, 318, 736, 1052
AcuI CTGAAG 4 cut(s) 500, 692, 782, 1320
AfaI GTAC 2 cut(s) 903, 1101
AfiI CCNNNNNNNGG 3 cut(s) 434, 682, 1338
AgsI TTSAA 9 cut(s) 302, 325, 492, 1004, 1009, 1051, 1057, 1184, 1367
AluBI AGCT 8 cut(s) 25, 279, 293, 314, 917, 980, 1165, 1313
AluI AGCT 8 cut(s) 25, 279, 293, 314, 917, 980, 1165, 1313
Alw21I GWGCWC 2 cut(s) 503, 1397
Alw26I GTCTC 3 cut(s) 461, 479, 1162
Alw44I GTGCAC 1 cut(s) 1393
AlwI GGATC 2 cut(s) 585, 739
Aor13HI TCCGGA 1 cut(s) 816
AoxI GGCC 1 cut(s) 46
ApaLI GTGCAC 1 cut(s) 1393
ApeKI GCWGC 1 cut(s) 220
ApoI RAATTY 4 cut(s) 207, 318, 736, 1052
Asp700I GAANNNNTTC 1 cut(s) 999
AspA2I CCTAGG 1 cut(s) 1321
AspLEI GCGC 2 cut(s) 79, 1403
AspS9I GGNCC 2 cut(s) 46, 197
AvaII GGWCC 1 cut(s) 197
AvrII CCTAGG 1 cut(s) 1321
BaeGI GKGCMC 1 cut(s) 1397
BarI GAAGNNNNNNTAC 2 cut(s) 14, 46
BbsI GAAGAC 2 cut(s) 347, 1131
Bbv12I GWGCWC 2 cut(s) 503, 1397
BbvI GCAGC 1 cut(s) 232
BccI CCATC 3 cut(s) 344, 568, 595
BcgI CGANNNNNNTGC 2 cut(s) 147, 181
BcoDI GTCTC 3 cut(s) 461, 479, 1162
BfaI CTAG 3 cut(s) 140, 1322, 1409
BfmI CTRYAG 3 cut(s) 218, 595, 986
BfuAI ACCTGC 1 cut(s) 431
BglII AGATCT 1 cut(s) 823
BisI GCNGC 2 cut(s) 107, 221
BlnI CCTAGG 1 cut(s) 1321
BlsI GCNGC 2 cut(s) 108, 222
Bme18I GGWCC 1 cut(s) 197
BmgT120I GGNCC 2 cut(s) 46, 197
BmiI GGNNCC 4 cut(s) 884, 996, 1119, 1318
BmsI GCATC 3 cut(s) 145, 257, 544
BpiI GAAGAC 2 cut(s) 347, 1131
BplI GAGNNNNNCTC 2 cut(s) 268, 300
BpmI CTGGAG 3 cut(s) 326, 630, 901
BpuEI CTTGAG 3 cut(s) 66, 831, 874
Bsa29I ATCGAT 1 cut(s) 1383
BsaJI CCNNGG 5 cut(s) 6, 377, 676, 748, 1321
BsaWI WCCGGW 2 cut(s) 816, 1281
Bsc4I CCNNNNNNNGG 3 cut(s) 434, 682, 1338
Bse1I ACTGG 2 cut(s) 309, 884
Bse3DI GCAATG 5 cut(s) 251, 276, 557, 920, 1251
BseAI TCCGGA 1 cut(s) 816
BseCI ATCGAT 1 cut(s) 1383
BseDI CCNNGG 5 cut(s) 6, 377, 676, 748, 1321
BseGI GGATG 5 cut(s) 559, 606, 613, 1227, 1296
BseLI CCNNNNNNNGG 3 cut(s) 434, 682, 1338
BseMI GCAATG 5 cut(s) 251, 276, 557, 920, 1251
BseMII CTCAG 4 cut(s) 384, 516, 576, 1157
BseNI ACTGG 2 cut(s) 309, 884
BseSI GKGCMC 1 cut(s) 1397
BseXI GCAGC 1 cut(s) 232
BsgI GTGCAG 1 cut(s) 177
Bsh1236I CGCG 2 cut(s) 77, 891
BshFI GGCC 1 cut(s) 48
BshVI ATCGAT 1 cut(s) 1383
BsiHKAI GWGCWC 2 cut(s) 503, 1397
BsiSI CCGG 2 cut(s) 817, 1282
BslFI GGGAC 1 cut(s) 640
BslI CCNNNNNNNGG 3 cut(s) 434, 682, 1338
BsmAI GTCTC 3 cut(s) 461, 479, 1162
BsmFI GGGAC 1 cut(s) 640
BsmI GAATGC 1 cut(s) 1210
BsnI GGCC 1 cut(s) 48
Bsp1286I GDGCHC 2 cut(s) 503, 1397
Bsp13I TCCGGA 1 cut(s) 816
Bsp1407I TGTACA 1 cut(s) 901
Bsp143I GATC 8 cut(s) 365, 577, 639, 744, 823, 834, 1380, 1384
Bsp19I CCATGG 1 cut(s) 748
BspACI CCGC 3 cut(s) 106, 605, 889
BspANI GGCC 1 cut(s) 48
BspCNI CTCAG 4 cut(s) 385, 515, 577, 1158
BspDI ATCGAT 1 cut(s) 1383
BspEI TCCGGA 1 cut(s) 816
BspFNI CGCG 2 cut(s) 77, 891
BspLI GGNNCC 4 cut(s) 884, 996, 1119, 1318
BspMAI CTGCAG 2 cut(s) 222, 599
BspMI ACCTGC 1 cut(s) 431
BspPI GGATC 2 cut(s) 585, 739
BsrBI CCGCTC 1 cut(s) 106
BsrDI GCAATG 5 cut(s) 251, 276, 557, 920, 1251
BsrGI TGTACA 1 cut(s) 901
BsrI ACTGG 2 cut(s) 309, 884
BssECI CCNNGG 5 cut(s) 6, 377, 676, 748, 1321
BssMI GATC 8 cut(s) 365, 577, 639, 744, 823, 834, 1380, 1384
BssNAI GTATAC 1 cut(s) 182
BssT1I CCWWGG 3 cut(s) 6, 748, 1321
Bst1107I GTATAC 1 cut(s) 182
Bst4CI ACNGT 3 cut(s) 498, 538, 1130
BstAUI TGTACA 1 cut(s) 901
BstC8I GCNNGC 3 cut(s) 111, 652, 1311
BstDEI CTNAG 6 cut(s) 393, 502, 585, 955, 1166, 1245
BstDSI CCRYGG 2 cut(s) 676, 748
BstF5I GGATG 5 cut(s) 559, 606, 613, 1227, 1296
BstFNI CGCG 2 cut(s) 77, 891
BstHHI GCGC 2 cut(s) 79, 1403
BstKTI GATC 8 cut(s) 368, 580, 642, 747, 826, 837, 1383, 1387
BstMAI GTCTC 3 cut(s) 461, 479, 1162
BstMBI GATC 8 cut(s) 365, 577, 639, 744, 823, 834, 1380, 1384
BstMWI GCNNNNNNNGC 1 cut(s) 1310
BstSFI CTRYAG 3 cut(s) 218, 595, 986
BstSLI GKGCMC 1 cut(s) 1397
BstUI CGCG 2 cut(s) 77, 891
BstV1I GCAGC 1 cut(s) 232
BstV2I GAAGAC 2 cut(s) 347, 1131
BstX2I RGATCY 2 cut(s) 577, 823
BstYI RGATCY 2 cut(s) 577, 823
BstZ17I GTATAC 1 cut(s) 182
Bsu15I ATCGAT 1 cut(s) 1383
BsuRI GGCC 1 cut(s) 48
BsuTUI ATCGAT 1 cut(s) 1383
BtgI CCRYGG 2 cut(s) 676, 748
BtsCI GGATG 5 cut(s) 559, 606, 613, 1227, 1296
BtsI GCAGTG 1 cut(s) 592
BtsIMutI CAGTG 1 cut(s) 592
BveI ACCTGC 1 cut(s) 431
Cac8I GCNNGC 3 cut(s) 111, 652, 1311
CfoI GCGC 2 cut(s) 79, 1403
Cfr13I GGNCC 2 cut(s) 46, 197
ClaI ATCGAT 1 cut(s) 1383
CseI GACGC 1 cut(s) 83
Csp6I GTAC 2 cut(s) 902, 1100
CspCI CAANNNNNGTGG 2 cut(s) 1075, 1110
CviAII CATG 5 cut(s) 401, 749, 781, 905, 1191
CviQI GTAC 2 cut(s) 902, 1100
DdeI CTNAG 6 cut(s) 393, 502, 585, 955, 1166, 1245
DpnI GATC 8 cut(s) 367, 579, 641, 746, 825, 836, 1382, 1386
DpnII GATC 8 cut(s) 365, 577, 639, 744, 823, 834, 1380, 1384
EciI GGCGGA 1 cut(s) 620
Eco130I CCWWGG 3 cut(s) 6, 748, 1321
Eco32I GATATC 1 cut(s) 948
Eco47I GGWCC 1 cut(s) 197
Eco57I CTGAAG 4 cut(s) 500, 692, 782, 1320
EcoRV GATATC 1 cut(s) 948
EcoT14I CCWWGG 3 cut(s) 6, 748, 1321
EcoT22I ATGCAT 1 cut(s) 559
ErhI CCWWGG 3 cut(s) 6, 748, 1321
FaeI CATG 5 cut(s) 404, 752, 784, 908, 1194
FalI AAGNNNNNCTT 2 cut(s) 1116, 1148
FaqI GGGAC 1 cut(s) 640
FatI CATG 5 cut(s) 400, 748, 780, 904, 1190
FauNDI CATATG 1 cut(s) 1258
FblI GTMKAC 1 cut(s) 181
Fnu4HI GCNGC 2 cut(s) 107, 221
FokI GGATG 5 cut(s) 566, 613, 620, 1214, 1303
Fsp4HI GCNGC 2 cut(s) 107, 221
FspBI CTAG 3 cut(s) 140, 1322, 1409
GlaI GCGC 2 cut(s) 78, 1402
GluI GCNGC 2 cut(s) 107, 221
GsuI CTGGAG 3 cut(s) 326, 630, 901
HaeIII GGCC 1 cut(s) 48
HapII CCGG 2 cut(s) 817, 1282
HgaI GACGC 1 cut(s) 83
HhaI GCGC 2 cut(s) 79, 1403
Hin1II CATG 5 cut(s) 404, 752, 784, 908, 1194
Hin6I GCGC 2 cut(s) 77, 1401
HinP1I GCGC 2 cut(s) 77, 1401
HincII GTYRAC 1 cut(s) 703
HindII GTYRAC 1 cut(s) 703
HindIII AAGCTT 1 cut(s) 23
HinfI GANTC 7 cut(s) 162, 214, 283, 438, 802, 1148, 1187
HpaII CCGG 2 cut(s) 817, 1282
Hpy166II GTNNAC 7 cut(s) 150, 182, 703, 877, 902, 1086, 1395
Hpy188I TCNGA 6 cut(s) 56, 505, 666, 711, 801, 834
Hpy8I GTNNAC 7 cut(s) 150, 182, 703, 877, 902, 1086, 1395
Hpy99I CGWCG 1 cut(s) 77
HpyAV CCTTC 7 cut(s) 221, 438, 475, 668, 716, 961, 985
HpyCH4III ACNGT 3 cut(s) 498, 538, 1130
HpyF10VI GCNNNNNNNGC 1 cut(s) 1310
HpyF3I CTNAG 6 cut(s) 393, 502, 585, 955, 1166, 1245
Hsp92II CATG 5 cut(s) 404, 752, 784, 908, 1194
HspAI GCGC 2 cut(s) 77, 1401
Kpn2I TCCGGA 1 cut(s) 816
Kzo9I GATC 8 cut(s) 365, 577, 639, 744, 823, 834, 1380, 1384
LmnI GCTCC 3 cut(s) 678, 882, 922
Lsp1109I GCAGC 1 cut(s) 232
LweI GCATC 3 cut(s) 145, 257, 544
MaeI CTAG 3 cut(s) 140, 1322, 1409
MaeIII GTNAC 3 cut(s) 396, 404, 1267
MalI GATC 8 cut(s) 367, 579, 641, 746, 825, 836, 1382, 1386
MbiI CCGCTC 1 cut(s) 106
MboI GATC 8 cut(s) 365, 577, 639, 744, 823, 834, 1380, 1384
MboII GAAGA 6 cut(s) 50, 347, 353, 788, 1136, 1390
MfeI CAATTG 2 cut(s) 1004, 1209
MflI RGATCY 2 cut(s) 577, 823
MhlI GDGCHC 2 cut(s) 503, 1397
MlyI GAGTC 3 cut(s) 208, 277, 447
MmeI TCCRAC 1 cut(s) 34
Mph1103I ATGCAT 1 cut(s) 559
MroI TCCGGA 1 cut(s) 816
MroXI GAANNNNTTC 1 cut(s) 999
MseI TTAA 4 cut(s) 528, 1107, 1113, 1335
MspI CCGG 2 cut(s) 817, 1282
MunI CAATTG 2 cut(s) 1004, 1209
Mva1269I GAATGC 1 cut(s) 1210
MvnI CGCG 2 cut(s) 77, 891
MwoI GCNNNNNNNGC 1 cut(s) 1310
NcoI CCATGG 1 cut(s) 748
NdeI CATATG 1 cut(s) 1258
NdeII GATC 8 cut(s) 365, 577, 639, 744, 823, 834, 1380, 1384
NlaIII CATG 5 cut(s) 404, 752, 784, 908, 1194
NlaIV GGNNCC 4 cut(s) 884, 996, 1119, 1318
NmeAIII GCCGAG 1 cut(s) 300
NsiI ATGCAT 1 cut(s) 559
PctI GAATGC 1 cut(s) 1210
PdmI GAANNNNTTC 1 cut(s) 999
PfeI GAWTC 4 cut(s) 162, 802, 1148, 1187
PkrI GCNGC 2 cut(s) 108, 222
PleI GAGTC 3 cut(s) 208, 277, 446
PpsI GAGTC 3 cut(s) 208, 277, 446
PspN4I GGNNCC 4 cut(s) 884, 996, 1119, 1318
PspPI GGNCC 2 cut(s) 46, 197
PstI CTGCAG 2 cut(s) 222, 599
PsuI RGATCY 2 cut(s) 577, 823
RsaI GTAC 2 cut(s) 903, 1101
RsaNI GTAC 2 cut(s) 902, 1100
SaqAI TTAA 4 cut(s) 528, 1107, 1113, 1335
SatI GCNGC 2 cut(s) 107, 221
Sau3AI GATC 8 cut(s) 365, 577, 639, 744, 823, 834, 1380, 1384
Sau96I GGNCC 2 cut(s) 46, 197
SchI GAGTC 3 cut(s) 208, 277, 447
SduI GDGCHC 2 cut(s) 503, 1397
SfaNI GCATC 3 cut(s) 145, 257, 544
SfcI CTRYAG 3 cut(s) 218, 595, 986
SinI GGWCC 1 cut(s) 197
SmlI CTYRAG 3 cut(s) 81, 846, 853
SmoI CTYRAG 3 cut(s) 81, 846, 853
SsiI CCGC 3 cut(s) 106, 605, 889
SspMI CTAG 3 cut(s) 140, 1322, 1409
StyI CCWWGG 3 cut(s) 6, 748, 1321
TaaI ACNGT 3 cut(s) 498, 538, 1130
TaqI TCGA 6 cut(s) 72, 167, 193, 364, 441, 1383
TatI WGTACW 1 cut(s) 901
TauI GCSGC 1 cut(s) 109
TfiI GAWTC 4 cut(s) 162, 802, 1148, 1187
Tru1I TTAA 4 cut(s) 528, 1107, 1113, 1335
Tru9I TTAA 4 cut(s) 528, 1107, 1113, 1335
TscAI CASTG 1 cut(s) 599
TseI GCWGC 1 cut(s) 220
TspDTI ATGAA 4 cut(s) 251, 347, 522, 1051
TspGWI ACGGA 2 cut(s) 665, 1071
TspRI CASTG 1 cut(s) 599
VneI GTGCAC 1 cut(s) 1393
VpaK11BI GGWCC 1 cut(s) 197
XapI RAATTY 4 cut(s) 207, 318, 736, 1052
XbaI TCTAGA 1 cut(s) 1408
XcmI CCANNNNNNNNNTGG 2 cut(s) 207, 347
XmaJI CCTAGG 1 cut(s) 1321
XmiI GTMKAC 1 cut(s) 181
XmnI GAANNNNTTC 1 cut(s) 999
XspI CTAG 3 cut(s) 140, 1322, 1409
Zsp2I ATGCAT 1 cut(s) 559
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.