Basic Information

Type: gene

Biological Identity

Species

rosa_rugosa

Chromosome

GWHBQTZ00000001

Orthogroup ID

OG0015823

Physical Location & Seq

Genomic Coordinates Reverse (-)

55620437 .. 55623028

Gene Structure 2592 bp

Loading structure...

UTR

Exon/CDS

Intron

Transcript / Protein ID

Rorug01G0463700.1

Sequence Viewer

CDS Protein Promoter (2k)

Length: 1287 bp

ATGCAGAAGCAACATCAATTCGGAGTGCTAAACTTGGACAGCATAATCATAAATGTAGACTCTGAAGCATTTTTAAAATACATACAGTTGGACCAATCCTCCACTGAAGCTAAACAGACGTATAATGAAGCCCTTGACAGACTGATTGAGACCATATTTCCAGCAGACCTATCATACCCGCTTGAGTTCGAGCACTTTAGGCATCTGGCCAGTAGGGCAAGCAATCAGACTGAGCTCGAGCAGTTGTTTTACCACCCAATACTGCTGTCCAGAGTAGAAAGAATACTTTTTGTCCATCATGCCTTCGTCATGATTGGACAAAAATGTATGACAGAGGACAAAACAATATGGAAGAGGCTAGAAGAAATGCAGAAGTTCATGAACATCGAGAACATAATCAGTGGCAAACCGATATTAGAGGCAGCGTACAACAGCTTTAAAGGGGAGTACAAAACGGATGCAAGGGCAGCTTTCAAATTCTACCGGCACTGCATCCTTCACTACAACGACTATTTGGAAGAGGTTGTAGCTGCCACTGTTATTCATGGTAATGTGAGAACTGGTTTTGTTGAGTTTACTTCTCGGAGCTGGGCTGAGATGATCTTGAAGTCCTACAATGGTCTCGGGATGCCAAACTACGCTCAGATATACCGCCTGAAATGGGATATGGATGCTACCGGTATGATGTGGCGCTGGGATTATGCTTACGAGCGTTGTTCGTACTTTGGTTTTAATGATGCAGGTGAAGAATTGAACGCCAACAAAGCGCTCTTGAGATACAAGCACTTGATACCTGCTGTAAATGAAAAACCAGCTGCTGGTGGTGGTCAGCAACATCAGGAAGGCGTGTCTGGTTTAACATATGAGATAGTTGAAGAGATTCTCTACAACAACTGGTTAGGTAATAGGTTTCTGTATCTATGTATGGAGGAATTGTGTAAGGAAAAAGACGGTTGTTACGTTATCCGCACCCTCAAGTTGTCGAACTTATTGTCATGCTCTTGCAAGTTTGACGAAAAGATTGGGAGTATAATCACCTGCCGCTATTGCGCCGACTGCAACGTGCCATTTGAATTGCAAAAGCAGGCTTGGCTATGCACCAAGGACTTCGGCAACCGGAAAAAAGTCCGAGGCTTATGGGATGCACTTCTTGTTTCAGCGGAATTATGTTCGCCGGTGGCCTGGACCAGTCACCAGATCAAACTTGAGCTCCTTACTTTGTGCCGAGTCAAAAATGTTATTATTTTCAGCCGAGAGATATTTACCACTATAATCCCGAGTGGATAA

Functional Annotation

Gene Ontology

Molecular Function
Biological Process
Cellular Component

GO:0001101 GO:0003674 GO:0003824 GO:0004672 GO:0004674 GO:0005575 GO:0005622 GO:0005623 GO:0006464 GO:0006468 GO:0006793 GO:0006796 GO:0006807 GO:0006810 GO:0006950 GO:0006970 GO:0006972 GO:0007154 GO:0007165 GO:0007275 GO:0008150 GO:0008152 GO:0009414 GO:0009415 GO:0009628 GO:0009651 GO:0009914 GO:0009926 GO:0009987 GO:0010035 GO:0010540 GO:0010817 GO:0016301 GO:0016310 GO:0016740 GO:0016772 GO:0016773 GO:0018105 GO:0018107 GO:0018193 GO:0018209 GO:0018210 GO:0019538 GO:0023052 GO:0032501 GO:0032502 GO:0035556 GO:0036211 GO:0042221 GO:0042538 GO:0043170 GO:0043412 GO:0044237 GO:0044238 GO:0044260 GO:0044267 GO:0044464 GO:0048856 GO:0050789 GO:0050794 GO:0050896 GO:0051179 GO:0051234 GO:0051716 GO:0060918 GO:0065007 GO:0065008 GO:0071704 GO:0140096 GO:1901564 GO:1901700

KEGG Pathways

Metabolic & Signaling

ko04068 ko04140 ko04150 ko04151 ko04152 ko04211 ko04213 ko04371 ko04530 ko04710 ko04714 ko04910 ko04920 ko04921 ko04922 ko04931 ko04932 ko05410 ko05418 map04068 map04140 map04150 map04151 map04152 map04211 map04213 map04371 map04530 map04710 map04714 map04910 map04920 map04921 map04922 map04931 map04932 map05410 map05418

Pfam Domains

Protein Families

NAF Pkinase

Protein Analysis

428

Amino Acids

49.68

Weight (kDa)

6.33

Isoelectric Point (pI)

42.31

Instability Index

Protein Domains (Pfam)

No Pfam domains detected for this protein.

Hydrophobicity Profile (Kyte-Doolittle)

AI Structure Prediction Report

Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter

Style Settings

Font Size (px)

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Align Labels (Cladogram)

Image

Tree File

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Publication-ready

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Orthologous Genes (Group: OG0015823)

Species	Orthologous Gene IDs
arabidopsis_thaliana	AT4G30960
fragaria_vesca	FvH4_1g01070
malus_domestica	MD15G1045200.v1.1 MD15G1153500.v1.1
prunus_persica	Prupe.7G261300_v2.0.a1
rosa_chinensis	RchiOBHm_Chr2g0085831
rosa_laevigata	RLG00000013813 RLG00000015723
rosa_multiflora	Rmu_sc0001748.1_g000016
rosa_roxburghii	Rroxscaffold_2G00155000
rosa_rugosa	Rorug01G0463700
rosa_samantha	Rh2BG013500 Rh2CG014000 Rh2DG015100
rosa_wichuraiana	Rw2G001130

Restriction Enzyme Sites

1 / 10

Enzyme	Recognition Site	Cut Count	Positions (bp)
AarI	CACCTGC	2 cut(s)	731, 1046
Acc36I	ACCTGC	3 cut(s)	731, 802, 1046
AccB7I	CCANNNNNTGG	1 cut(s)	818
AccI	GTMKAC	1 cut(s)	57
AciI	CCGC	5 cut(s)	179, 652, 967, 1042, 1160
AcoI	YGGCCR	1 cut(s)	207
AcsI	RAATTY	1 cut(s)	476
AcuI	CTGAAG	2 cut(s)	84, 126
AfaI	GTAC	3 cut(s)	428, 449, 722
AfeI	AGCGCT	1 cut(s)	768
AfiI	CCNNNNNNNGG	2 cut(s)	661, 818
AgeI	ACCGGT	1 cut(s)	677
AgsI	TTSAA	5 cut(s)	475, 607, 754, 875, 1073
AjnI	CCWGG	1 cut(s)	1181
AluBI	AGCT	8 cut(s)	110, 235, 435, 470, 530, 588, 815, 1210
AluI	AGCT	8 cut(s)	110, 235, 435, 470, 530, 588, 815, 1210
Alw21I	GWGCWC	3 cut(s)	195, 237, 1212
Alw26I	GTCTC	2 cut(s)	143, 626
AlwNI	CAGNNNCTG	1 cut(s)	818
Ama87I	CYCGRG	3 cut(s)	236, 623, 1276
Aor51HI	AGCGCT	1 cut(s)	768
AoxI	GGCC	2 cut(s)	207, 1179
ApeKI	GCWGC	4 cut(s)	422, 467, 530, 815
ApoI	RAATTY	1 cut(s)	476
ArsI	GACNNNNNNTTYG	2 cut(s)	977, 1009
AsiGI	ACCGGT	1 cut(s)	677
Asp700I	GAANNNNTTC	1 cut(s)	879
AspLEI	GCGC	3 cut(s)	693, 769, 1052
AspS9I	GGNCC	2 cut(s)	91, 1185
AsuHPI	GGTGA	3 cut(s)	755, 1027, 1184
AvaI	CYCGRG	3 cut(s)	236, 623, 1276
AvaII	GGWCC	2 cut(s)	91, 1185
BalI	TGGCCA	1 cut(s)	209
BanII	GRGCYC	2 cut(s)	237, 1212
Bbv12I	GWGCWC	3 cut(s)	195, 237, 1212
BbvI	GCAGC	4 cut(s)	434, 479, 517, 802
BccI	CCATC	1 cut(s)	303
BciT130I	CCWGG	1 cut(s)	1183
BcoDI	GTCTC	2 cut(s)	143, 626
BfaI	CTAG	1 cut(s)	359
BfoI	RGCGCY	2 cut(s)	694, 770
BfuAI	ACCTGC	3 cut(s)	731, 802, 1046
BglI	GCCNNNNNGGC	1 cut(s)	215
BisI	GCNGC	5 cut(s)	423, 468, 531, 816, 1042
BlsI	GCNGC	5 cut(s)	424, 469, 532, 817, 1043
Bme1390I	CCNGG	1 cut(s)	1183
Bme18I	GGWCC	2 cut(s)	91, 1185
BmeT110I	CYCGRG	3 cut(s)	236, 623, 1276
BmgT120I	GGNCC	2 cut(s)	91, 1185
BmrFI	CCNGG	1 cut(s)	1183
BmsI	GCATC	7 cut(s)	211, 448, 501, 618, 661, 727, 1132
BpuEI	CTTGAG	4 cut(s)	203, 793, 959, 1226
BsaI	GGTCTC	2 cut(s)	143, 626
BsaJI	CCNNGG	2 cut(s)	1101, 1129
BsaWI	WCCGGW	2 cut(s)	677, 1116
BsaXI	ACNNNNNCTCC	6 cut(s)	83, 113, 920, 950, 1194, 1224
Bsc4I	CCNNNNNNNGG	2 cut(s)	661, 818
Bse118I	RCCGGY	3 cut(s)	483, 677, 1174
Bse1I	ACTGG	4 cut(s)	210, 565, 899, 1188
BseBI	CCWGG	1 cut(s)	1183
BseDI	CCNNGG	2 cut(s)	1101, 1129
BseGI	GGATG	5 cut(s)	463, 492, 633, 676, 1147
BseLI	CCNNNNNNNGG	2 cut(s)	661, 818
BseMII	CTCAG	3 cut(s)	222, 585, 656
BseNI	ACTGG	4 cut(s)	210, 565, 899, 1188
BseXI	GCAGC	4 cut(s)	434, 479, 517, 802
BseYI	CCCAGC	2 cut(s)	588, 693
BshFI	GGCC	2 cut(s)	209, 1181
BshTI	ACCGGT	1 cut(s)	677
BsiHKAI	GWGCWC	3 cut(s)	195, 237, 1212
BsiHKCI	CYCGRG	3 cut(s)	236, 623, 1276
BsiSI	CCGG	4 cut(s)	484, 678, 1117, 1175
BslI	CCNNNNNNNGG	2 cut(s)	661, 818
BsmAI	GTCTC	2 cut(s)	143, 626
BsnI	GGCC	2 cut(s)	209, 1181
Bso31I	GGTCTC	2 cut(s)	143, 626
BsoBI	CYCGRG	3 cut(s)	236, 623, 1276
Bsp1286I	GDGCHC	3 cut(s)	195, 237, 1212
Bsp143I	GATC	2 cut(s)	600, 1197
BspACI	CCGC	5 cut(s)	179, 652, 967, 1042, 1160
BspANI	GGCC	2 cut(s)	209, 1181
BspCNI	CTCAG	3 cut(s)	223, 586, 655
BspHI	TCATGA	2 cut(s)	309, 378
BspMI	ACCTGC	3 cut(s)	731, 802, 1046
BspTNI	GGTCTC	2 cut(s)	143, 626
BsrFI	RCCGGY	3 cut(s)	483, 677, 1174
BsrI	ACTGG	4 cut(s)	210, 565, 899, 1188
BssAI	RCCGGY	3 cut(s)	483, 677, 1174
BssECI	CCNNGG	2 cut(s)	1101, 1129
BssMI	GATC	2 cut(s)	600, 1197
BssT1I	CCWWGG	1 cut(s)	1101
Bst2UI	CCWGG	1 cut(s)	1183
Bst4CI	ACNGT	3 cut(s)	87, 538, 953
Bst6I	CTCTTC	3 cut(s)	347, 513, 870
BstC8I	GCNNGC	2 cut(s)	220, 1086
BstDEI	CTNAG	3 cut(s)	231, 594, 642
BstF5I	GGATG	5 cut(s)	463, 492, 633, 676, 1147
BstH2I	RGCGCY	2 cut(s)	694, 770
BstHHI	GCGC	3 cut(s)	693, 769, 1052
BstKTI	GATC	2 cut(s)	603, 1200
BstMAI	GTCTC	2 cut(s)	143, 626
BstMBI	GATC	2 cut(s)	600, 1197
BstMWI	GCNNNNNNNGC	7 cut(s)	199, 215, 467, 764, 1047, 1056, 1090
BstNI	CCWGG	1 cut(s)	1183
BstSCI	CCNGG	1 cut(s)	1181
BstV1I	GCAGC	4 cut(s)	434, 479, 517, 802
BsuRI	GGCC	2 cut(s)	209, 1181
BtsCI	GGATG	5 cut(s)	463, 492, 633, 676, 1147
BtsI	GCAGTG	1 cut(s)	487
BtsIMutI	CAGTG	4 cut(s)	102, 406, 487, 534
BveI	ACCTGC	3 cut(s)	731, 802, 1046
Cac8I	GCNNGC	2 cut(s)	220, 1086
CaiI	CAGNNNCTG	1 cut(s)	818
CciI	TCATGA	2 cut(s)	309, 378
CfoI	GCGC	3 cut(s)	693, 769, 1052
Cfr10I	RCCGGY	3 cut(s)	483, 677, 1174
Cfr13I	GGNCC	2 cut(s)	91, 1185
Csp6I	GTAC	3 cut(s)	427, 448, 721
CspAI	ACCGGT	1 cut(s)	677
CviAII	CATG	5 cut(s)	299, 310, 379, 545, 996
CviQI	GTAC	3 cut(s)	427, 448, 721
DdeI	CTNAG	3 cut(s)	231, 594, 642
DpnI	GATC	2 cut(s)	602, 1199
DpnII	GATC	2 cut(s)	600, 1197
DraI	TTTAAA	2 cut(s)	75, 439
EaeI	YGGCCR	1 cut(s)	207
Eam1104I	CTCTTC	3 cut(s)	347, 513, 870
EarI	CTCTTC	3 cut(s)	347, 513, 870
Ecl136II	GAGCTC	2 cut(s)	235, 1210
Eco130I	CCWWGG	1 cut(s)	1101
Eco24I	GRGCYC	2 cut(s)	237, 1212
Eco31I	GGTCTC	2 cut(s)	143, 626
Eco47I	GGWCC	2 cut(s)	91, 1185
Eco47III	AGCGCT	1 cut(s)	768
Eco53kI	GAGCTC	2 cut(s)	235, 1210
Eco57I	CTGAAG	2 cut(s)	84, 126
Eco88I	CYCGRG	3 cut(s)	236, 623, 1276
EcoICRI	GAGCTC	2 cut(s)	235, 1210
EcoRII	CCWGG	1 cut(s)	1181
EcoT14I	CCWWGG	1 cut(s)	1101
EcoT38I	GRGCYC	2 cut(s)	237, 1212
ErhI	CCWWGG	1 cut(s)	1101
FaeI	CATG	5 cut(s)	302, 313, 382, 548, 999
FalI	AAGNNNNNCTT	2 cut(s)	454, 486
FatI	CATG	5 cut(s)	298, 309, 378, 544, 995
FauI	CCCGC	1 cut(s)	186
FauNDI	CATATG	1 cut(s)	862
FblI	GTMKAC	1 cut(s)	57
Fnu4HI	GCNGC	5 cut(s)	423, 468, 531, 816, 1042
FokI	GGATG	5 cut(s)	470, 479, 640, 683, 1154
FriOI	GRGCYC	2 cut(s)	237, 1212
Fsp4HI	GCNGC	5 cut(s)	423, 468, 531, 816, 1042
FspBI	CTAG	1 cut(s)	359
GlaI	GCGC	3 cut(s)	692, 768, 1051
GluI	GCNGC	5 cut(s)	423, 468, 531, 816, 1042
GsaI	CCCAGC	2 cut(s)	592, 697
HaeII	RGCGCY	2 cut(s)	694, 770
HaeIII	GGCC	2 cut(s)	209, 1181
HapII	CCGG	4 cut(s)	484, 678, 1117, 1175
HhaI	GCGC	3 cut(s)	693, 769, 1052
Hin1II	CATG	5 cut(s)	302, 313, 382, 548, 999
Hin6I	GCGC	3 cut(s)	691, 767, 1050
HinP1I	GCGC	3 cut(s)	691, 767, 1050
HinfI	GANTC	3 cut(s)	59, 880, 1227
HpaII	CCGG	4 cut(s)	484, 678, 1117, 1175
HphI	GGTGA	3 cut(s)	755, 1027, 1184
Hpy166II	GTNNAC	2 cut(s)	58, 576
Hpy188I	TCNGA	6 cut(s)	23, 64, 228, 585, 645, 1130
Hpy188III	TCNNGA	9 cut(s)	270, 310, 379, 388, 604, 625, 772, 839, 1276
Hpy8I	GTNNAC	2 cut(s)	58, 576
HpyAV	CCTTC	3 cut(s)	313, 506, 836
HpyCH4III	ACNGT	3 cut(s)	87, 538, 953
HpyCH4IV	ACGT	3 cut(s)	119, 960, 1062
HpyF10VI	GCNNNNNNNGC	7 cut(s)	199, 215, 467, 764, 1047, 1056, 1090
HpyF3I	CTNAG	3 cut(s)	231, 594, 642
HpySE526I	ACGT	3 cut(s)	119, 960, 1062
Hsp92II	CATG	5 cut(s)	302, 313, 382, 548, 999
HspAI	GCGC	3 cut(s)	691, 767, 1050
Kzo9I	GATC	2 cut(s)	600, 1197
LmnI	GCTCC	2 cut(s)	585, 1215
Lsp1109I	GCAGC	4 cut(s)	434, 479, 517, 802
LweI	GCATC	7 cut(s)	211, 448, 501, 618, 661, 727, 1132
MaeI	CTAG	1 cut(s)	359
MaeII	ACGT	3 cut(s)	119, 960, 1062
MaeIII	GTNAC	2 cut(s)	956, 1190
MalI	GATC	2 cut(s)	602, 1199
MboI	GATC	2 cut(s)	600, 1197
MboII	GAAGA	5 cut(s)	364, 374, 530, 758, 887
MhlI	GDGCHC	3 cut(s)	195, 237, 1212
MlsI	TGGCCA	1 cut(s)	209
MluCI	AATT	6 cut(s)	17, 476, 749, 932, 1073, 1163
MluNI	TGGCCA	1 cut(s)	209
MlyI	GAGTC	2 cut(s)	53, 1236
MmeI	TCCRAC	1 cut(s)	69
MnlI	CCTC	8 cut(s)	109, 328, 348, 412, 514, 922, 983, 1124
Mox20I	TGGCCA	1 cut(s)	209
MroXI	GAANNNNTTC	1 cut(s)	879
MscI	TGGCCA	1 cut(s)	209
MseI	TTAA	4 cut(s)	74, 438, 732, 857
MslI	CAYNNNNRTG	1 cut(s)	549
Msp20I	TGGCCA	1 cut(s)	209
MspA1I	CMGCKG	2 cut(s)	815, 1160
MspI	CCGG	4 cut(s)	484, 678, 1117, 1175
MspR9I	CCNGG	1 cut(s)	1183
MvaI	CCWGG	1 cut(s)	1183
MwoI	GCNNNNNNNGC	7 cut(s)	199, 215, 467, 764, 1047, 1056, 1090
NdeI	CATATG	1 cut(s)	862
NdeII	GATC	2 cut(s)	600, 1197
NlaIII	CATG	5 cut(s)	302, 313, 382, 548, 999
NmeAIII	GCCGAG	2 cut(s)	1250, 1277
NmuCI	GTSAC	1 cut(s)	1190
PaeR7I	CTCGAG	1 cut(s)	236
PagI	TCATGA	2 cut(s)	309, 378
PaqCI	CACCTGC	2 cut(s)	731, 1046
PcsI	WCGNNNNNNNCGW	1 cut(s)	957
PdmI	GAANNNNTTC	1 cut(s)	879
PfeI	GAWTC	1 cut(s)	880
PflMI	CCANNNNNTGG	1 cut(s)	818
PinAI	ACCGGT	1 cut(s)	677
PkrI	GCNGC	5 cut(s)	424, 469, 532, 817, 1043
PleI	GAGTC	2 cut(s)	53, 1235
PpsI	GAGTC	2 cut(s)	53, 1235
Psp124BI	GAGCTC	2 cut(s)	237, 1212
Psp6I	CCWGG	1 cut(s)	1181
PspFI	CCCAGC	2 cut(s)	588, 693
PspGI	CCWGG	1 cut(s)	1181
PspPI	GGNCC	2 cut(s)	91, 1185
PspXI	VCTCGAGB	1 cut(s)	236
PstNI	CAGNNNCTG	1 cut(s)	818
PvuII	CAGCTG	1 cut(s)	815
RsaI	GTAC	3 cut(s)	428, 449, 722
RsaNI	GTAC	3 cut(s)	427, 448, 721
RseI	CAYNNNNRTG	1 cut(s)	549
SacI	GAGCTC	2 cut(s)	237, 1212
SaqAI	TTAA	4 cut(s)	74, 438, 732, 857
SatI	GCNGC	5 cut(s)	423, 468, 531, 816, 1042
Sau3AI	GATC	2 cut(s)	600, 1197
Sau96I	GGNCC	2 cut(s)	91, 1185
SchI	GAGTC	2 cut(s)	53, 1236
ScrFI	CCNGG	1 cut(s)	1183
SduI	GDGCHC	3 cut(s)	195, 237, 1212
SfaNI	GCATC	7 cut(s)	211, 448, 501, 618, 661, 727, 1132
Sfr274I	CTCGAG	1 cut(s)	236
SgrAI	CRCCGGYG	1 cut(s)	1174
SinI	GGWCC	2 cut(s)	91, 1185
SlaI	CTCGAG	1 cut(s)	236
SmiMI	CAYNNNNRTG	1 cut(s)	549
SmlI	CTYRAG	5 cut(s)	182, 236, 772, 974, 1205
SmoI	CTYRAG	5 cut(s)	182, 236, 772, 974, 1205
Sse9I	AATT	6 cut(s)	17, 476, 749, 932, 1073, 1163
SsiI	CCGC	5 cut(s)	179, 652, 967, 1042, 1160
SspMI	CTAG	1 cut(s)	359
SstI	GAGCTC	2 cut(s)	237, 1212
StyD4I	CCNGG	1 cut(s)	1181
StyI	CCWWGG	1 cut(s)	1101
TaaI	ACNGT	3 cut(s)	87, 538, 953
TaiI	ACGT	3 cut(s)	122, 963, 1065
TaqI	TCGA	4 cut(s)	189, 237, 387, 983
TasI	AATT	6 cut(s)	17, 476, 749, 932, 1073, 1163
TatI	WGTACW	1 cut(s)	447
TauI	GCSGC	1 cut(s)	1044
TfiI	GAWTC	1 cut(s)	880
Tru1I	TTAA	4 cut(s)	74, 438, 732, 857
Tru9I	TTAA	4 cut(s)	74, 438, 732, 857
TscAI	CASTG	4 cut(s)	109, 406, 494, 541
TseFI	GTSAC	1 cut(s)	1190
TseI	GCWGC	4 cut(s)	422, 467, 530, 815
Tsp45I	GTSAC	1 cut(s)	1190
TspDTI	ATGAA	5 cut(s)	141, 367, 395, 533, 819
TspGWI	ACGGA	1 cut(s)	470
TspRI	CASTG	4 cut(s)	109, 406, 494, 541
Van91I	CCANNNNNTGG	1 cut(s)	818
VpaK11BI	GGWCC	2 cut(s)	91, 1185
XapI	RAATTY	1 cut(s)	476
XhoI	CTCGAG	1 cut(s)	236
XmiI	GTMKAC	1 cut(s)	57
XmnI	GAANNNNTTC	1 cut(s)	879
XspI	CTAG	1 cut(s)	359

Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.