Basic Information

Type: gene

Biological Identity

Species

malus_domestica

Chromosome

Chr03

Orthogroup ID

OG0005639

Physical Location & Seq

Genomic Coordinates Reverse (-)

34327560 .. 34333205

Gene Structure 5646 bp

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UTR

Exon/CDS

Intron

Transcript / Protein ID

MD03G1255900.v1.1.491

Sequence Viewer

CDS Protein Promoter (2k)

Length: 1830 bp

ATGAAGGCCCCTGCTTCTTCCATGGCGATATCGAATTGGGTTTTTGTGTTTTCGATTGTTGTCTGCTTTTTCGCATCTGGGTCGCTCGCAATTGAGAATTTCCACCAAGCATTTCCTATTGTGGAACCTGATCCTGGTCATACAAAACTTCGTCTTTCAAGGGAAGGGTTGGAGGCCATTGAAAGAATAACAAATCCAATTGCAGCTGTTGCCGTTATTGGACCGTACCGCTCTGGAAAATCTTTTTTGCTCAACCAACTGCTCTCCCTTTCTTGTTATGAAGGGTTTGGTGTTGGACACATGCGTGACACAAAAACAAAAGGGATTTGGGTATGGGGAACACCAATAGAATTGGATATTGACGGAGTGAAAACTTCAGTTTTTTACCTTGATACTGAGGGATTTGAAAGTGTTGGGAAGTCAAATGTATATGATGACCGGATTTTTGCTCTGGCAACTGTTATGAGTTCTGTCCTTGTTTATAACCTGCCTGAGACGATCCGTGAAGCTGACATTGCCCGTTTATCATTTGCTGTTGAGCTTGCTGAAGAATTTTATGGAAGGTCCACAGGACAAGATGTTGCTTTTGAACCTGCAAAGCTATTGTGGCTCATCCAGCGTGATTTTTTACAAGGGAAATCTGTGCAAGAAATGGTTAATGAAGCTCTTCTTCGCGTCCCTAACAGTGATGGCAACAAAAACATTGATATGGTCAACCAGATCCGAGATTCTTTGGCTATTATGGGTGATAATAGCACCGCCTTCAGTTTACCACAACCTCACCTTGAGCGGACGAAACTCTGCGACATGAAGGATGGTGAGCTTGACCCGATGTATGTTAAGAAAAAGGAACAACTAAAACAGCTTGTTTCTAGTATCATCCGTCCAAAGATTGTGCAGGGAAAAACTCTAAATGGAAAAGAGTTTGTATCTTTTCTGGAGCAGATTCTTGAAGCGTTGAACAAGGGGGAGATCCCATCAACAGGTTCTCTGGTGGAGGTTTTCAATAAGGGTATTCTTGAGCGATGCTTAAAGCTGTACCATGAAAGGATGGAAAAACTCAGTTTACCTCTCGTAGAGCAATCTGTGCAAGAATACCATGAACGGTCCATGGAGGAAGTGATGAAACTTTTTGAGGATCAACATTTTGGCCGTCACCATGCAAAGAAGTCAGTTGAGCAACTACAAGAAGAAGTAGACAAGGTGTTTAAGAATGTGGTCATGGCAAACAAATATCAATCTTCAAAGCTCTGTGAGGCATTGTATACCAGATGTGAGGATAAAATGGACCAACTACAAGTTCTCAGACTTCCTTCCATGGCAAAATTCAACGCAGGTTTCCTGCAGTGCAACCAAAGTTTTGAGCAAGAGTGTGTTGGACCTGCAAAAGTAAACTATGAGGTTCGCATGATGAAGATGTTGGGCAAGTCACGATCTCTATTTATAAAAGAGTACAATCACCGACTCTTCAATTGGTTGGTCGCCTTCTCCCTTGTCATGGTGGTCGTTGGCCGGTTTATCATAAAGTTTATATTGATTGAAATCGGGGCCTGGATCATGTTCATCTTCTTAGAGACGTACACGAGGATGTTTTGGTCTGCAGAGTCTCTCTACTACAACCCCGTTTGGCATGTAATAGTAGCCACTTGGGAAACACTCGTATACAGTCCCGTCCTTGATCTGGACAGATGGGCTATTCCAGCCGGTGTCTTGGTAGCTCTGTTCATACTATATTGGCGGTGTTACGGAAGAAGGAAACACGGGTCCAGATGGATCTTACCCTTGTACAATAATCACAAAGGCGGCTCAAATCGCCCAAGATCAGACTGA

Functional Annotation

Gene Ontology

Molecular Function
Biological Process
Cellular Component

GO:0002376 GO:0003674 GO:0005488 GO:0005515 GO:0005575 GO:0005622 GO:0005623 GO:0005634 GO:0005737 GO:0005829 GO:0006950 GO:0006952 GO:0006955 GO:0008150 GO:0009987 GO:0010033 GO:0034097 GO:0034341 GO:0042221 GO:0042802 GO:0042803 GO:0043226 GO:0043227 GO:0043229 GO:0043231 GO:0044424 GO:0044444 GO:0044464 GO:0045087 GO:0046983 GO:0048471 GO:0050896 GO:0051716 GO:0070887 GO:0071310 GO:0071345 GO:0071346

KEGG Pathways

Metabolic & Signaling

ko04621 map04621

Pfam Domains

Protein Families

GBP GBP_C

Protein Analysis

610

Amino Acids

69.76

Weight (kDa)

7.2

Isoelectric Point (pI)

41.97

Instability Index

Protein Domains (Pfam)

Domain Name	Pfam ID	Position	E-value	Description
GBP	PF02263	49 - 295	7.2e-36	Guanylate-binding protein, N-terminal domain
GBP_C	PF02841	301 - 430	4e-08	Guanylate-binding protein, C-terminal domain

Hydrophobicity Profile (Kyte-Doolittle)

AI Structure Prediction Report

Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter

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Align Labels (Cladogram)

Image

Tree File

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Publication-ready

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Orthologous Genes (Group: OG0005639)

Species	Orthologous Gene IDs
arabidopsis_thaliana	AT2G38840 AT2G38840
fragaria_vesca	FvH4_2g22730 FvH4_2g22730 FvH4_2g22730 FvH4_2g22730 FvH4_2g22730
malus_domestica	MD03G1255900.v1.1 MD11G1276500.v1.1
prunus_persica	Prupe.8G233000_v2.0.a1 Prupe.8G233000_v2.0.a1 Prupe.8G233000_v2.0.a1 Prupe.8G233000_v2.0.a1
pyrus_communis	pycom03g20260 pycom11g24470
rosa_chinensis	RchiOBHm_Chr6g0289661
rosa_laevigata	RLG00000012280
rosa_multiflora	Rmu_sc0008255.1_g000010
rosa_roxburghii	Rroxscaffold_7G00177720
rosa_rugosa	Rorug02G0296500 Rorug06G0205600 Rorug07G0206300 Rorug07G0206400
rosa_samantha	Rh6AG317200 Rh6BG324300 Rh6CG330400 Rh6DG315600
rosa_wichuraiana	Rw6G027360

Restriction Enzyme Sites

1 / 10

Enzyme	Recognition Site	Cut Count	Positions (bp)
AanI	TTATAA	2 cut(s)	483, 1445
Acc36I	ACCTGC	4 cut(s)	495, 601, 1325, 1390
AccBSI	CCGCTC	2 cut(s)	231, 790
AccI	GTMKAC	3 cut(s)	1197, 1265, 1662
AccII	CGCG	1 cut(s)	675
AciI	CCGC	5 cut(s)	229, 759, 790, 1738, 1803
AclWI	GGATC	7 cut(s)	125, 493, 715, 967, 1146, 1562, 1781
AcoI	YGGCCR	2 cut(s)	1150, 1510
AcsI	RAATTY	3 cut(s)	97, 551, 1325
AcuI	CTGAAG	3 cut(s)	360, 567, 748
AfaI	GTAC	5 cut(s)	227, 1040, 1454, 1580, 1787
AfiI	CCNNNNNNNGG	4 cut(s)	134, 983, 1498, 1681
AjnI	CCWGG	2 cut(s)	133, 1550
AjuI	GAANNNNNNNTTGG	2 cut(s)	1284, 1316
AleI	CACNNNNGTG	1 cut(s)	303
Alw26I	GTCTC	3 cut(s)	488, 1568, 1611
AlwI	GGATC	7 cut(s)	125, 493, 715, 967, 1146, 1562, 1781
AoxI	GGCC	5 cut(s)	6, 174, 1150, 1510, 1548
ApeKI	GCWGC	1 cut(s)	203
ApoI	RAATTY	3 cut(s)	97, 551, 1325
ArsI	GACNNNNNNTTYG	2 cut(s)	428, 460
Asp700I	GAANNNNTTC	1 cut(s)	666
AspS9I	GGNCC	8 cut(s)	7, 221, 564, 1107, 1288, 1379, 1548, 1764
AsuHPI	GGTGA	5 cut(s)	758, 773, 830, 1148, 1451
AvaII	GGWCC	6 cut(s)	221, 564, 1107, 1288, 1379, 1764
BauI	CACGAG	1 cut(s)	1582
BbvI	GCAGC	1 cut(s)	215
BccI	CCATC	6 cut(s)	683, 809, 985, 1045, 1683, 1764
BceAI	ACGGC	2 cut(s)	197, 1137
BcgI	CGANNNNNNTGC	2 cut(s)	63, 97
BciT130I	CCWGG	2 cut(s)	135, 1552
BcoDI	GTCTC	3 cut(s)	488, 1568, 1611
BfaI	CTAG	1 cut(s)	873
BfmI	CTRYAG	2 cut(s)	1343, 1599
BfuAI	ACCTGC	4 cut(s)	495, 601, 1325, 1390
BisI	GCNGC	2 cut(s)	204, 1804
BlsI	GCNGC	2 cut(s)	205, 1805
Bme1390I	CCNGG	2 cut(s)	135, 1552
Bme18I	GGWCC	6 cut(s)	221, 564, 1107, 1288, 1379, 1764
BmgT120I	GGNCC	8 cut(s)	7, 221, 564, 1107, 1288, 1379, 1548, 1764
BmiI	GGNNCC	4 cut(s)	9, 126, 1549, 1765
BmrFI	CCNGG	2 cut(s)	135, 1552
BmsI	GCATC	2 cut(s)	83, 1016
BpmI	CTGGAG	1 cut(s)	959
BpuEI	CTTGAG	2 cut(s)	806, 1040
BsaBI	GATNNNNATC	1 cut(s)	1541
BsaJI	CCNNGG	3 cut(s)	21, 1110, 1317
BsaWI	WCCGGW	1 cut(s)	438
Bsc4I	CCNNNNNNNGG	4 cut(s)	134, 983, 1498, 1681
Bse118I	RCCGGY	2 cut(s)	1512, 1703
Bse3DI	GCAATG	1 cut(s)	513
Bse8I	GATNNNNATC	1 cut(s)	1541
BseBI	CCWGG	2 cut(s)	135, 1552
BseDI	CCNNGG	3 cut(s)	21, 1110, 1317
BseGI	GGATG	5 cut(s)	612, 820, 879, 1056, 1593
BseJI	GATNNNNATC	1 cut(s)	1541
BseLI	CCNNNNNNNGG	4 cut(s)	134, 983, 1498, 1681
BseMI	GCAATG	1 cut(s)	513
BseMII	CTCAG	4 cut(s)	387, 483, 1075, 1318
BseXI	GCAGC	1 cut(s)	215
BsgI	GTGCAG	1 cut(s)	917
Bsh1236I	CGCG	1 cut(s)	675
BshFI	GGCC	5 cut(s)	8, 176, 1152, 1512, 1550
BsiSI	CCGG	3 cut(s)	439, 1513, 1704
BslFI	GGGAC	2 cut(s)	662, 1653
BslI	CCNNNNNNNGG	4 cut(s)	134, 983, 1498, 1681
BsmAI	GTCTC	3 cut(s)	488, 1568, 1611
BsmBI	CGTCTC	2 cut(s)	488, 1568
BsmFI	GGGAC	2 cut(s)	662, 1653
BsnI	GGCC	5 cut(s)	8, 176, 1152, 1512, 1550
Bsp1407I	TGTACA	1 cut(s)	1785
Bsp19I	CCATGG	3 cut(s)	21, 1110, 1317
BspACI	CCGC	5 cut(s)	229, 759, 790, 1738, 1803
BspANI	GGCC	5 cut(s)	8, 176, 1152, 1512, 1550
BspCNI	CTCAG	4 cut(s)	388, 484, 1074, 1317
BspFNI	CGCG	1 cut(s)	675
BspLI	GGNNCC	4 cut(s)	9, 126, 1549, 1765
BspMAI	CTGCAG	2 cut(s)	1347, 1603
BspMI	ACCTGC	4 cut(s)	495, 601, 1325, 1390
BspPI	GGATC	7 cut(s)	125, 493, 715, 967, 1146, 1562, 1781
BspQI	GCTCTTC	1 cut(s)	672
BsrBI	CCGCTC	2 cut(s)	231, 790
BsrDI	GCAATG	1 cut(s)	513
BsrFI	RCCGGY	2 cut(s)	1512, 1703
BsrGI	TGTACA	1 cut(s)	1785
BssAI	RCCGGY	2 cut(s)	1512, 1703
BssECI	CCNNGG	3 cut(s)	21, 1110, 1317
BssNAI	GTATAC	2 cut(s)	1266, 1663
BssSI	CACGAG	1 cut(s)	1582
BssT1I	CCWWGG	3 cut(s)	21, 1110, 1317
Bst1107I	GTATAC	2 cut(s)	1266, 1663
Bst2BI	CACGAG	1 cut(s)	1582
Bst2UI	CCWGG	2 cut(s)	135, 1552
Bst4CI	ACNGT	5 cut(s)	225, 460, 686, 1107, 1667
Bst6I	CTCTTC	2 cut(s)	672, 1472
BstAPI	GCANNNNNTGC	2 cut(s)	209, 1087
BstAUI	TGTACA	1 cut(s)	1785
BstC8I	GCNNGC	2 cut(s)	87, 543
BstDEI	CTNAG	5 cut(s)	396, 492, 1061, 1304, 1570
BstDSI	CCRYGG	3 cut(s)	21, 1110, 1317
BstF5I	GGATG	5 cut(s)	612, 820, 879, 1056, 1593
BstFNI	CGCG	1 cut(s)	675
BstMAI	GTCTC	3 cut(s)	488, 1568, 1611
BstMWI	GCNNNNNNNGC	7 cut(s)	209, 515, 607, 616, 1087, 1700, 1812
BstNI	CCWGG	2 cut(s)	135, 1552
BstNSI	RCATGY	2 cut(s)	304, 1634
BstSCI	CCNGG	2 cut(s)	133, 1550
BstSFI	CTRYAG	2 cut(s)	1343, 1599
BstUI	CGCG	1 cut(s)	675
BstV1I	GCAGC	1 cut(s)	215
BstX2I	RGATCY	3 cut(s)	720, 972, 1773
BstYI	RGATCY	3 cut(s)	720, 972, 1773
BstZ17I	GTATAC	2 cut(s)	1266, 1663
BsuRI	GGCC	5 cut(s)	8, 176, 1152, 1512, 1550
BtgI	CCRYGG	3 cut(s)	21, 1110, 1317
BtgZI	GCGATG	1 cut(s)	1039
BtsCI	GGATG	5 cut(s)	612, 820, 879, 1056, 1593
BtsI	GCAGTG	1 cut(s)	1352
BtsIMutI	CAGTG	2 cut(s)	691, 1352
BveI	ACCTGC	4 cut(s)	495, 601, 1325, 1390
Cac8I	GCNNGC	2 cut(s)	87, 543
Cfr10I	RCCGGY	2 cut(s)	1512, 1703
Cfr13I	GGNCC	8 cut(s)	7, 221, 564, 1107, 1288, 1379, 1548, 1764
CseI	GACGC	1 cut(s)	664
Csp6I	GTAC	5 cut(s)	226, 1039, 1453, 1579, 1786
CviQI	GTAC	5 cut(s)	226, 1039, 1453, 1579, 1786
DdeI	CTNAG	5 cut(s)	396, 492, 1061, 1304, 1570
EaeI	YGGCCR	2 cut(s)	1150, 1510
Eam1104I	CTCTTC	2 cut(s)	672, 1472
EarI	CTCTTC	2 cut(s)	672, 1472
Eco130I	CCWWGG	3 cut(s)	21, 1110, 1317
Eco32I	GATATC	1 cut(s)	30
Eco47I	GGWCC	6 cut(s)	221, 564, 1107, 1288, 1379, 1764
Eco57I	CTGAAG	3 cut(s)	360, 567, 748
EcoO109I	RGGNCCY	2 cut(s)	7, 1548
EcoRII	CCWGG	2 cut(s)	133, 1550
EcoRV	GATATC	1 cut(s)	30
EcoT14I	CCWWGG	3 cut(s)	21, 1110, 1317
ErhI	CCWWGG	3 cut(s)	21, 1110, 1317
Esp3I	CGTCTC	2 cut(s)	488, 1568
FalI	AAGNNNNNCTT	2 cut(s)	654, 686
FaqI	GGGAC	2 cut(s)	662, 1653
FblI	GTMKAC	3 cut(s)	1197, 1265, 1662
Fnu4HI	GCNGC	2 cut(s)	204, 1804
FokI	GGATG	5 cut(s)	599, 827, 866, 1063, 1600
Fsp4HI	GCNGC	2 cut(s)	204, 1804
FspBI	CTAG	1 cut(s)	873
GluI	GCNGC	2 cut(s)	204, 1804
GsuI	CTGGAG	1 cut(s)	959
HaeIII	GGCC	5 cut(s)	8, 176, 1152, 1512, 1550
HapII	CCGG	3 cut(s)	439, 1513, 1704
HgaI	GACGC	1 cut(s)	664
HincII	GTYRAC	1 cut(s)	715
HindII	GTYRAC	1 cut(s)	715
HinfI	GANTC	4 cut(s)	728, 946, 1464, 1604
HpaII	CCGG	3 cut(s)	439, 1513, 1704
HphI	GGTGA	5 cut(s)	758, 773, 830, 1148, 1451
Hpy166II	GTNNAC	9 cut(s)	567, 715, 770, 1067, 1198, 1266, 1393, 1581, 1663
Hpy188I	TCNGA	3 cut(s)	725, 1307, 1825
Hpy188III	TCNNGA	7 cut(s)	234, 938, 950, 1019, 1431, 1682, 1767
Hpy8I	GTNNAC	9 cut(s)	567, 715, 770, 1067, 1198, 1266, 1393, 1581, 1663
HpyAV	CCTTC	8 cut(s)	158, 275, 555, 772, 805, 1323, 1495, 1746
HpyCH4III	ACNGT	5 cut(s)	225, 460, 686, 1107, 1667
HpyCH4IV	ACGT	1 cut(s)	1577
HpyF10VI	GCNNNNNNNGC	7 cut(s)	209, 515, 607, 616, 1087, 1700, 1812
HpyF3I	CTNAG	5 cut(s)	396, 492, 1061, 1304, 1570
HpySE526I	ACGT	1 cut(s)	1577
LguI	GCTCTTC	1 cut(s)	672
LmnI	GCTCC	1 cut(s)	940
Lsp1109I	GCAGC	1 cut(s)	215
LweI	GCATC	2 cut(s)	83, 1016
MaeI	CTAG	1 cut(s)	873
MaeII	ACGT	1 cut(s)	1577
MaeIII	GTNAC	4 cut(s)	305, 1154, 1428, 1742
MbiI	CCGCTC	2 cut(s)	231, 790
MfeI	CAATTG	3 cut(s)	90, 198, 1471
MflI	RGATCY	3 cut(s)	720, 972, 1773
MluCI	AATT	8 cut(s)	34, 90, 97, 198, 350, 551, 1325, 1471
MlyI	GAGTC	2 cut(s)	1458, 1613
MmeI	TCCRAC	3 cut(s)	150, 274, 1357
MroXI	GAANNNNTTC	1 cut(s)	666
MseI	TTAA	4 cut(s)	657, 840, 1031, 1209
MslI	CAYNNNNRTG	3 cut(s)	303, 707, 1586
MspA1I	CMGCKG	1 cut(s)	206
MspI	CCGG	3 cut(s)	439, 1513, 1704
MspR9I	CCNGG	2 cut(s)	135, 1552
MunI	CAATTG	3 cut(s)	90, 198, 1471
MvaI	CCWGG	2 cut(s)	135, 1552
MvnI	CGCG	1 cut(s)	675
MwoI	GCNNNNNNNGC	7 cut(s)	209, 515, 607, 616, 1087, 1700, 1812
NcoI	CCATGG	3 cut(s)	21, 1110, 1317
NlaIV	GGNNCC	4 cut(s)	9, 126, 1549, 1765
NmuCI	GTSAC	3 cut(s)	305, 1154, 1428
NspI	RCATGY	2 cut(s)	304, 1634
OliI	CACNNNNGTG	1 cut(s)	303
PciSI	GCTCTTC	1 cut(s)	672
PdmI	GAANNNNTTC	1 cut(s)	666
PfeI	GAWTC	2 cut(s)	728, 946
PkrI	GCNGC	2 cut(s)	205, 1805
PleI	GAGTC	2 cut(s)	1458, 1612
PpsI	GAGTC	2 cut(s)	1458, 1612
PsiI	TTATAA	2 cut(s)	483, 1445
Psp6I	CCWGG	2 cut(s)	133, 1550
PspGI	CCWGG	2 cut(s)	133, 1550
PspN4I	GGNNCC	4 cut(s)	9, 126, 1549, 1765
PspPI	GGNCC	8 cut(s)	7, 221, 564, 1107, 1288, 1379, 1548, 1764
PstI	CTGCAG	2 cut(s)	1347, 1603
PsuI	RGATCY	3 cut(s)	720, 972, 1773
PvuII	CAGCTG	1 cut(s)	206
RsaI	GTAC	5 cut(s)	227, 1040, 1454, 1580, 1787
RsaNI	GTAC	5 cut(s)	226, 1039, 1453, 1579, 1786
RseI	CAYNNNNRTG	3 cut(s)	303, 707, 1586
SapI	GCTCTTC	1 cut(s)	672
SaqAI	TTAA	4 cut(s)	657, 840, 1031, 1209
SatI	GCNGC	2 cut(s)	204, 1804
Sau96I	GGNCC	8 cut(s)	7, 221, 564, 1107, 1288, 1379, 1548, 1764
SchI	GAGTC	2 cut(s)	1458, 1613
ScrFI	CCNGG	2 cut(s)	135, 1552
SfaNI	GCATC	2 cut(s)	83, 1016
SfcI	CTRYAG	2 cut(s)	1343, 1599
SinI	GGWCC	6 cut(s)	221, 564, 1107, 1288, 1379, 1764
SmiMI	CAYNNNNRTG	3 cut(s)	303, 707, 1586
SmlI	CTYRAG	2 cut(s)	785, 1019
SmoI	CTYRAG	2 cut(s)	785, 1019
Sse9I	AATT	8 cut(s)	34, 90, 97, 198, 350, 551, 1325, 1471
SsiI	CCGC	5 cut(s)	229, 759, 790, 1738, 1803
SspMI	CTAG	1 cut(s)	873
StyD4I	CCNGG	2 cut(s)	133, 1550
StyI	CCWWGG	3 cut(s)	21, 1110, 1317
TaaI	ACNGT	5 cut(s)	225, 460, 686, 1107, 1667
TaiI	ACGT	1 cut(s)	1580
TaqI	TCGA	2 cut(s)	32, 53
TasI	AATT	8 cut(s)	34, 90, 97, 198, 350, 551, 1325, 1471
TatI	WGTACW	2 cut(s)	1452, 1785
TauI	GCSGC	1 cut(s)	1806
TfiI	GAWTC	2 cut(s)	728, 946
Tru1I	TTAA	4 cut(s)	657, 840, 1031, 1209
Tru9I	TTAA	4 cut(s)	657, 840, 1031, 1209
TscAI	CASTG	2 cut(s)	691, 1352
TseFI	GTSAC	3 cut(s)	305, 1154, 1428
TseI	GCWGC	1 cut(s)	203
Tsp45I	GTSAC	3 cut(s)	305, 1154, 1428
TspGWI	ACGGA	4 cut(s)	378, 491, 872, 1761
TspRI	CASTG	2 cut(s)	691, 1352
VpaK11BI	GGWCC	6 cut(s)	221, 564, 1107, 1288, 1379, 1764
XapI	RAATTY	3 cut(s)	97, 551, 1325
XceI	RCATGY	2 cut(s)	304, 1634
XmiI	GTMKAC	3 cut(s)	1197, 1265, 1662
XmnI	GAANNNNTTC	1 cut(s)	666
XspI	CTAG	1 cut(s)	873

Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.