MD09G1078700.v1.1

Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH

Basic Information

Type: gene
Biological Identity
malus_domestica
Chr09
Physical Location & Seq
Forward (+)
5509738 .. 5512235
2498 bp
Loading structure...
UTR
Exon/CDS
Intron
MD09G1078700.v1.1.491

Sequence Viewer

Length: 1416 bp
ATGGGCCAAAATTTGGCCCTCAACATTGCAGAGAAAGGCTTCCCCATTTCGGTATACAACAGAACTACCTCCAAAGTTGATGAGACTGTTGAGCGAGCTAAAAAGGAAGGAAACCTTCCCCTTTATGGATTCCATGATCCCGAATCTTTTGTTAAGTCAATCCAGAAACCCCGTGTCGTGATCATGCTTGTCAAGGCTGGGGTGCCTGTTGACCAGACCATAAAGACCCTTTCCGTCTACCTGGAGAAAGGCGACTGCATCATTGATGGTGGTAATGAGTGGTATGAGAACACTGAGAGGAGGGAGAAAGCCATGGCCGAATTAGGTCTTCTTTACCTTGGAATGGGAGTTTCAGGTGGTGAGGAGGGGGCTCGATACGGGCCTTCTATGATGCCTGGAGGATCCTTTGAGGCCTATAAGTACATTGAAGACATTCTTCTTAAGGTGTCAGCTCAAGTTCCGGACAGTGGTCCTTGTGTGACTTACATTGGCAAAGGTGGGTCTGGTAACTTTGTCAAGATGATTCATAATGGGATTGAATACGGTGATATGCAGCTCATAGCGGAGGCTTATGATGTGCTGAAATCAGTGGGAAAGTTGTCAAATGAGGAACTCCAAAAAGTTTTCTCAGAGTGGAACAAGGGTGAGCTTCTCAGCTTCCTGATTGAAATCACTGCCGATATATTTGGAATCAAGGATGACAAGGGAGATGGATATTTGGTTGACAAGGTTTTGGACAAGACTGGCATGAAGGGTACTGGTAAATGGACCGTACAGCAAGCTGCTGAACTATCAGTTGCAGCTCCAACAATTGAATCTTCTTTGGATGCAAGGTTCCTTAGTGGGTTAAAGGACGAGAGGGTTAAAGCAGCTAAAGTGTTCAAGTCAGCTGGCTTTGAGGATAGCTTGAATGCCCCAGAGGTGGATAAGGCAAAGTTGATCGATGATGTGAGGCAAGCTCTTTATGCATCCAAGATATGCAGTTATGCACAAGGGATGAATCTGATCCGTGCAAAGAGTATCGAGAAGGGATGGGACTTGAAGTTGGGCGAATTGGCCAGGATTTGGAAGGGAGGATGCATCATTCGTGCAGTGTTCCTGGACAGAATTAAGAAGGCCTATGATAGGAATGCTGATCTCGCAAACCTTCTCGTGGACCCAGAGTTCTCAAAAGAGATTGTTGAGAGGCAGTCTGCCTGGAGAAGGGTGGTATGCCTTGCTATCAACTCAGGCATCAGCACCCCAGGTATGTCAGCAAGCCTTGCTTATTTTGACTCCTACAGAAGGGATACCCTACCGGCGAACTTGGTCCAAGCTCAACGTGACTACTTTGGTGCTCATACATACGAACGAACTGACATGGAAGGCGCTTTCCATACTGAATGGTTCAAGATCGCCAAACAGTCAAAGATCTAA

Protein Analysis

472

Amino Acids

52.17

Weight (kDa)

6.03

Isoelectric Point (pI)

26.41

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
NAD_binding_2 PF03446 1 - 164 2.6e-40 NAD binding domain of 6-phosphogluconate dehydrogenase
6PGD PF00393 169 - 462 2e-128 6-phosphogluconate dehydrogenase, C-terminal domain
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

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Publication-ready

Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AccB1I GGYRCC 1 cut(s) 202
AccB7I CCANNNNNTGG 2 cut(s) 13, 1065
AccI GTMKAC 2 cut(s) 54, 237
AccIII TCCGGA 1 cut(s) 460
AciI CCGC 1 cut(s) 563
AclWI GGATC 4 cut(s) 131, 396, 409, 1000
AcoI YGGCCR 2 cut(s) 315, 1056
AcsI RAATTY 1 cut(s) 10
AfaI GTAC 3 cut(s) 422, 757, 774
AflII CTTAAG 1 cut(s) 440
AgsI TTSAA 8 cut(s) 428, 539, 668, 815, 883, 910, 1042, 1390
AjnI CCWGG 6 cut(s) 240, 394, 1058, 1098, 1196, 1243
AloI GAACNNNNNNTCC 4 cut(s) 818, 850, 1148, 1180
Alw21I GWGCWC 1 cut(s) 1339
Alw26I GTCTC 1 cut(s) 77
AlwI GGATC 4 cut(s) 131, 396, 409, 1000
Aor13HI TCCGGA 1 cut(s) 460
AoxI GGCC 7 cut(s) 4, 15, 315, 380, 411, 1056, 1116
ApeKI GCWGC 4 cut(s) 553, 782, 800, 869
ApoI RAATTY 1 cut(s) 10
Asp700I GAANNNNTTC 2 cut(s) 38, 432
AspLEI GCGC 1 cut(s) 1370
AspS9I GGNCC 7 cut(s) 4, 16, 380, 470, 768, 1156, 1309
AsuHPI GGTGA 3 cut(s) 371, 557, 656
AvaII GGWCC 4 cut(s) 470, 768, 1156, 1309
BalI TGGCCA 1 cut(s) 1058
BamHI GGATCC 1 cut(s) 401
BanI GGYRCC 1 cut(s) 202
BanII GRGCYC 1 cut(s) 373
BauI CACGAG 1 cut(s) 1151
BbsI GAAGAC 2 cut(s) 320, 435
Bbv12I GWGCWC 1 cut(s) 1339
BbvI GCAGC 4 cut(s) 565, 769, 812, 881
BccI CCATC 3 cut(s) 260, 704, 1026
BciT130I CCWGG 6 cut(s) 242, 396, 1060, 1100, 1198, 1245
BciVI GTATCC 1 cut(s) 1282
BclI TGATCA 1 cut(s) 180
BcoDI GTCTC 1 cut(s) 77
BfmI CTRYAG 1 cut(s) 1279
BfoI RGCGCY 1 cut(s) 1371
BfrI CTTAAG 1 cut(s) 440
BfuI GTATCC 1 cut(s) 1282
BglII AGATCT 1 cut(s) 1410
BisI GCNGC 4 cut(s) 554, 783, 801, 870
BlsI GCNGC 4 cut(s) 555, 784, 802, 871
Bme1390I CCNGG 6 cut(s) 242, 396, 1060, 1100, 1198, 1245
Bme18I GGWCC 4 cut(s) 470, 768, 1156, 1309
BmgT120I GGNCC 7 cut(s) 4, 16, 380, 470, 768, 1156, 1309
BmiI GGNNCC 4 cut(s) 204, 403, 836, 1158
BmrFI CCNGG 6 cut(s) 242, 396, 1060, 1100, 1198, 1245
BmsI GCATC 7 cut(s) 267, 381, 817, 977, 1067, 1089, 1242
BoxI GACNNNNGTC 1 cut(s) 468
BpiI GAAGAC 2 cut(s) 320, 435
BplI GAGNNNNNCTC 2 cut(s) 943, 975
BpmI CTGGAG 3 cut(s) 263, 417, 1219
BpuEI CTTGAG 1 cut(s) 438
Bsa29I ATCGAT 1 cut(s) 942
BsaBI GATNNNNATC 1 cut(s) 668
BsaJI CCNNGG 3 cut(s) 312, 337, 1243
BsaWI WCCGGW 1 cut(s) 460
Bse118I RCCGGY 1 cut(s) 1297
Bse1I ACTGG 2 cut(s) 748, 763
Bse3DI GCAATG 1 cut(s) 24
Bse8I GATNNNNATC 1 cut(s) 668
BseAI TCCGGA 1 cut(s) 460
BseBI CCWGG 6 cut(s) 242, 396, 1060, 1100, 1198, 1245
BseCI ATCGAT 1 cut(s) 942
BseDI CCNNGG 3 cut(s) 312, 337, 1243
BseGI GGATG 6 cut(s) 703, 832, 968, 1002, 1037, 1082
BseJI GATNNNNATC 1 cut(s) 668
BseMI GCAATG 1 cut(s) 24
BseMII CTCAG 4 cut(s) 285, 642, 667, 1242
BseNI ACTGG 2 cut(s) 748, 763
BseRI GAGGAG 2 cut(s) 313, 377
BseXI GCAGC 4 cut(s) 565, 769, 812, 881
BseYI CCCAGC 1 cut(s) 197
BsgI GTGCAG 1 cut(s) 1110
BshFI GGCC 7 cut(s) 6, 17, 317, 382, 413, 1058, 1118
BshNI GGYRCC 1 cut(s) 202
BshVI ATCGAT 1 cut(s) 942
BsiHKAI GWGCWC 1 cut(s) 1339
BsiSI CCGG 2 cut(s) 461, 1298
BslFI GGGAC 1 cut(s) 1049
BsmAI GTCTC 1 cut(s) 77
BsmFI GGGAC 1 cut(s) 1049
BsmI GAATGC 2 cut(s) 916, 1135
BsnI GGCC 7 cut(s) 6, 17, 317, 382, 413, 1058, 1118
Bsp1286I GDGCHC 2 cut(s) 373, 1339
Bsp13I TCCGGA 1 cut(s) 460
Bsp143I GATC 8 cut(s) 136, 180, 401, 939, 1005, 1135, 1392, 1410
Bsp19I CCATGG 1 cut(s) 312
BspACI CCGC 1 cut(s) 563
BspANI GGCC 7 cut(s) 6, 17, 317, 382, 413, 1058, 1118
BspCNI CTCAG 4 cut(s) 286, 641, 666, 1241
BspDI ATCGAT 1 cut(s) 942
BspEI TCCGGA 1 cut(s) 460
BspLI GGNNCC 4 cut(s) 204, 403, 836, 1158
BspPI GGATC 4 cut(s) 131, 396, 409, 1000
BspT107I GGYRCC 1 cut(s) 202
BspTI CTTAAG 1 cut(s) 440
BsrDI GCAATG 1 cut(s) 24
BsrFI RCCGGY 1 cut(s) 1297
BsrI ACTGG 2 cut(s) 748, 763
BssAI RCCGGY 1 cut(s) 1297
BssECI CCNNGG 3 cut(s) 312, 337, 1243
BssMI GATC 8 cut(s) 136, 180, 401, 939, 1005, 1135, 1392, 1410
BssNAI GTATAC 1 cut(s) 55
BssSI CACGAG 1 cut(s) 1151
BssT1I CCWWGG 2 cut(s) 312, 337
Bst1107I GTATAC 1 cut(s) 55
Bst2BI CACGAG 1 cut(s) 1151
Bst2UI CCWGG 6 cut(s) 242, 396, 1060, 1100, 1198, 1245
Bst4CI ACNGT 5 cut(s) 88, 467, 545, 772, 1404
BstAFI CTTAAG 1 cut(s) 440
BstAPI GCANNNNNTGC 1 cut(s) 1262
BstC8I GCNNGC 5 cut(s) 96, 780, 892, 957, 1258
BstDEI CTNAG 5 cut(s) 294, 628, 653, 839, 1228
BstDSI CCRYGG 1 cut(s) 312
BstENI CCTNNNNNAGG 3 cut(s) 1123, 1201, 1282
BstF5I GGATG 6 cut(s) 703, 832, 968, 1002, 1037, 1082
BstH2I RGCGCY 1 cut(s) 1371
BstHHI GCGC 1 cut(s) 1370
BstKTI GATC 8 cut(s) 139, 183, 404, 942, 1008, 1138, 1395, 1413
BstMAI GTCTC 1 cut(s) 77
BstMBI GATC 8 cut(s) 136, 180, 401, 939, 1005, 1135, 1392, 1410
BstMWI GCNNNNNNNGC 3 cut(s) 965, 1139, 1262
BstNI CCWGG 6 cut(s) 242, 396, 1060, 1100, 1198, 1245
BstPAI GACNNNNGTC 1 cut(s) 468
BstSCI CCNGG 6 cut(s) 240, 394, 1058, 1098, 1196, 1243
BstSFI CTRYAG 1 cut(s) 1279
BstV1I GCAGC 4 cut(s) 565, 769, 812, 881
BstV2I GAAGAC 2 cut(s) 320, 435
BstX2I RGATCY 2 cut(s) 401, 1410
BstYI RGATCY 2 cut(s) 401, 1410
BstZ17I GTATAC 1 cut(s) 55
Bsu15I ATCGAT 1 cut(s) 942
BsuI GTATCC 1 cut(s) 1282
BsuRI GGCC 7 cut(s) 6, 17, 317, 382, 413, 1058, 1118
BsuTUI ATCGAT 1 cut(s) 942
BtgI CCRYGG 1 cut(s) 312
BtsCI GGATG 6 cut(s) 703, 832, 968, 1002, 1037, 1082
BtsI GCAGTG 2 cut(s) 672, 1098
BtsIMutI CAGTG 5 cut(s) 291, 472, 594, 672, 1098
Cac8I GCNNGC 5 cut(s) 96, 780, 892, 957, 1258
CfoI GCGC 1 cut(s) 1370
Cfr10I RCCGGY 1 cut(s) 1297
Cfr13I GGNCC 7 cut(s) 4, 16, 380, 470, 768, 1156, 1309
ClaI ATCGAT 1 cut(s) 942
Csp6I GTAC 3 cut(s) 421, 756, 773
CviAII CATG 5 cut(s) 134, 184, 313, 748, 1360
CviQI GTAC 3 cut(s) 421, 756, 773
DdeI CTNAG 5 cut(s) 294, 628, 653, 839, 1228
DpnI GATC 8 cut(s) 138, 182, 403, 941, 1007, 1137, 1394, 1412
DpnII GATC 8 cut(s) 136, 180, 401, 939, 1005, 1135, 1392, 1410
EaeI YGGCCR 2 cut(s) 315, 1056
Eco130I CCWWGG 2 cut(s) 312, 337
Eco147I AGGCCT 2 cut(s) 413, 1118
Eco24I GRGCYC 1 cut(s) 373
Eco47I GGWCC 4 cut(s) 470, 768, 1156, 1309
EcoNI CCTNNNNNAGG 3 cut(s) 1123, 1201, 1282
EcoRII CCWGG 6 cut(s) 240, 394, 1058, 1098, 1196, 1243
EcoT14I CCWWGG 2 cut(s) 312, 337
EcoT22I ATGCAT 2 cut(s) 970, 1082
EcoT38I GRGCYC 1 cut(s) 373
ErhI CCWWGG 2 cut(s) 312, 337
FaeI CATG 5 cut(s) 137, 187, 316, 751, 1363
FalI AAGNNNNNCTT 6 cut(s) 99, 131, 420, 452, 1249, 1281
FaqI GGGAC 1 cut(s) 1049
FatI CATG 5 cut(s) 133, 183, 312, 747, 1359
FbaI TGATCA 1 cut(s) 180
FblI GTMKAC 2 cut(s) 54, 237
Fnu4HI GCNGC 4 cut(s) 554, 783, 801, 870
FokI GGATG 6 cut(s) 710, 839, 955, 1009, 1044, 1089
FriOI GRGCYC 1 cut(s) 373
Fsp4HI GCNGC 4 cut(s) 554, 783, 801, 870
GlaI GCGC 1 cut(s) 1369
GluI GCNGC 4 cut(s) 554, 783, 801, 870
GsaI CCCAGC 1 cut(s) 201
GsuI CTGGAG 3 cut(s) 263, 417, 1219
HaeII RGCGCY 1 cut(s) 1371
HaeIII GGCC 7 cut(s) 6, 17, 317, 382, 413, 1058, 1118
HapII CCGG 2 cut(s) 461, 1298
HhaI GCGC 1 cut(s) 1370
Hin1II CATG 5 cut(s) 137, 187, 316, 751, 1363
Hin6I GCGC 1 cut(s) 1368
HinP1I GCGC 1 cut(s) 1368
HincII GTYRAC 2 cut(s) 211, 724
HindII GTYRAC 2 cut(s) 211, 724
HinfI GANTC 7 cut(s) 129, 143, 523, 690, 815, 1000, 1274
HpaII CCGG 2 cut(s) 461, 1298
HphI GGTGA 3 cut(s) 371, 557, 656
Hpy166II GTNNAC 5 cut(s) 55, 211, 238, 724, 1156
Hpy188I TCNGA 2 cut(s) 631, 1005
Hpy188III TCNNGA 8 cut(s) 140, 163, 178, 461, 517, 661, 1024, 1390
Hpy8I GTNNAC 5 cut(s) 55, 211, 238, 724, 1156
HpyCH4III ACNGT 5 cut(s) 88, 467, 545, 772, 1404
HpyCH4IV ACGT 1 cut(s) 1321
HpyF10VI GCNNNNNNNGC 3 cut(s) 965, 1139, 1262
HpyF3I CTNAG 5 cut(s) 294, 628, 653, 839, 1228
HpySE526I ACGT 1 cut(s) 1321
Hsp92II CATG 5 cut(s) 137, 187, 316, 751, 1363
HspAI GCGC 1 cut(s) 1368
Kpn2I TCCGGA 1 cut(s) 460
Ksp22I TGATCA 1 cut(s) 180
Kzo9I GATC 8 cut(s) 136, 180, 401, 939, 1005, 1135, 1392, 1410
LmnI GCTCC 1 cut(s) 808
Lsp1109I GCAGC 4 cut(s) 565, 769, 812, 881
LweI GCATC 7 cut(s) 267, 381, 817, 977, 1067, 1089, 1242
MaeII ACGT 1 cut(s) 1321
MaeIII GTNAC 3 cut(s) 478, 506, 1322
MalI GATC 8 cut(s) 138, 182, 403, 941, 1007, 1137, 1394, 1412
MboI GATC 8 cut(s) 136, 180, 401, 939, 1005, 1135, 1392, 1410
MboII GAAGA 4 cut(s) 320, 428, 440, 810
MfeI CAATTG 1 cut(s) 810
MflI RGATCY 2 cut(s) 401, 1410
MhlI GDGCHC 2 cut(s) 373, 1339
MlsI TGGCCA 1 cut(s) 1058
MluCI AATT 5 cut(s) 10, 320, 810, 1052, 1107
MluNI TGGCCA 1 cut(s) 1058
MlyI GAGTC 1 cut(s) 1268
MmeI TCCRAC 1 cut(s) 830
Mox20I TGGCCA 1 cut(s) 1058
Mph1103I ATGCAT 2 cut(s) 970, 1082
MroI TCCGGA 1 cut(s) 460
MroXI GAANNNNTTC 2 cut(s) 38, 432
MscI TGGCCA 1 cut(s) 1058
MseI TTAA 5 cut(s) 153, 441, 848, 864, 1110
Msp20I TGGCCA 1 cut(s) 1058
MspA1I CMGCKG 1 cut(s) 890
MspCI CTTAAG 1 cut(s) 440
MspI CCGG 2 cut(s) 461, 1298
MspR9I CCNGG 6 cut(s) 242, 396, 1060, 1100, 1198, 1245
MunI CAATTG 1 cut(s) 810
Mva1269I GAATGC 2 cut(s) 916, 1135
MvaI CCWGG 6 cut(s) 242, 396, 1060, 1100, 1198, 1245
MwoI GCNNNNNNNGC 3 cut(s) 965, 1139, 1262
NcoI CCATGG 1 cut(s) 312
NdeII GATC 8 cut(s) 136, 180, 401, 939, 1005, 1135, 1392, 1410
NlaIII CATG 5 cut(s) 137, 187, 316, 751, 1363
NlaIV GGNNCC 4 cut(s) 204, 403, 836, 1158
NmuCI GTSAC 2 cut(s) 478, 1322
NsiI ATGCAT 2 cut(s) 970, 1082
PceI AGGCCT 2 cut(s) 413, 1118
PctI GAATGC 2 cut(s) 916, 1135
PdmI GAANNNNTTC 2 cut(s) 38, 432
PfeI GAWTC 6 cut(s) 129, 143, 523, 690, 815, 1000
PflMI CCANNNNNTGG 2 cut(s) 13, 1065
PfoI TCCNGGA 1 cut(s) 1098
PkrI GCNGC 4 cut(s) 555, 784, 802, 871
PleI GAGTC 1 cut(s) 1268
PpsI GAGTC 1 cut(s) 1268
PshAI GACNNNNGTC 1 cut(s) 468
Psp6I CCWGG 6 cut(s) 240, 394, 1058, 1098, 1196, 1243
PspFI CCCAGC 1 cut(s) 197
PspGI CCWGG 6 cut(s) 240, 394, 1058, 1098, 1196, 1243
PspN4I GGNNCC 4 cut(s) 204, 403, 836, 1158
PspPI GGNCC 7 cut(s) 4, 16, 380, 470, 768, 1156, 1309
PsuI RGATCY 2 cut(s) 401, 1410
PvuII CAGCTG 1 cut(s) 890
RsaI GTAC 3 cut(s) 422, 757, 774
RsaNI GTAC 3 cut(s) 421, 756, 773
SaqAI TTAA 5 cut(s) 153, 441, 848, 864, 1110
SatI GCNGC 4 cut(s) 554, 783, 801, 870
Sau3AI GATC 8 cut(s) 136, 180, 401, 939, 1005, 1135, 1392, 1410
Sau96I GGNCC 7 cut(s) 4, 16, 380, 470, 768, 1156, 1309
SchI GAGTC 1 cut(s) 1268
ScrFI CCNGG 6 cut(s) 242, 396, 1060, 1100, 1198, 1245
SduI GDGCHC 2 cut(s) 373, 1339
SfaNI GCATC 7 cut(s) 267, 381, 817, 977, 1067, 1089, 1242
SfcI CTRYAG 1 cut(s) 1279
SinI GGWCC 4 cut(s) 470, 768, 1156, 1309
SmlI CTYRAG 2 cut(s) 440, 453
SmoI CTYRAG 2 cut(s) 440, 453
Sse9I AATT 5 cut(s) 10, 320, 810, 1052, 1107
SseBI AGGCCT 2 cut(s) 413, 1118
SsiI CCGC 1 cut(s) 563
StuI AGGCCT 2 cut(s) 413, 1118
StyD4I CCNGG 6 cut(s) 240, 394, 1058, 1098, 1196, 1243
StyI CCWWGG 2 cut(s) 312, 337
TaaI ACNGT 5 cut(s) 88, 467, 545, 772, 1404
TaiI ACGT 1 cut(s) 1324
TaqI TCGA 3 cut(s) 373, 942, 1023
TasI AATT 5 cut(s) 10, 320, 810, 1052, 1107
TatI WGTACW 1 cut(s) 420
TfiI GAWTC 6 cut(s) 129, 143, 523, 690, 815, 1000
Tru1I TTAA 5 cut(s) 153, 441, 848, 864, 1110
Tru9I TTAA 5 cut(s) 153, 441, 848, 864, 1110
TscAI CASTG 5 cut(s) 298, 472, 594, 679, 1098
TseFI GTSAC 2 cut(s) 478, 1322
TseI GCWGC 4 cut(s) 553, 782, 800, 869
Tsp45I GTSAC 2 cut(s) 478, 1322
TspDTI ATGAA 3 cut(s) 515, 764, 1013
TspGWI ACGGA 2 cut(s) 223, 998
TspRI CASTG 5 cut(s) 298, 472, 594, 679, 1098
Van91I CCANNNNNTGG 2 cut(s) 13, 1065
Vha464I CTTAAG 1 cut(s) 440
VpaK11BI GGWCC 4 cut(s) 470, 768, 1156, 1309
XagI CCTNNNNNAGG 3 cut(s) 1123, 1201, 1282
XapI RAATTY 1 cut(s) 10
XmiI GTMKAC 2 cut(s) 54, 237
XmnI GAANNNNTTC 2 cut(s) 38, 432
Zsp2I ATGCAT 2 cut(s) 970, 1082
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.