Basic Information

Type: gene

Biological Identity

Species

malus_domestica

Chromosome

Chr17

Orthogroup ID

OG0007870

Physical Location & Seq

Genomic Coordinates Forward (+)

2511187 .. 2513803

Gene Structure 2617 bp

Loading structure...

UTR

Exon/CDS

Intron

Transcript / Protein ID

MD17G1034800.v1.1.491

Sequence Viewer

CDS Protein Promoter (2k)

Length: 1158 bp

ATGGCGAGTAAGGGTGTGATTGCTTCTGCAGTTCGAGCTCTTGCTTCATCAGGAAGCTCAGCATCATCAACAACTTTCACCAGGCACCTCCATGCATCTGGTGGAAGCAAAAAGATTGTTGGGGTGTTTTACAAGGCAAATGAGTATGCAGAATTGAACCCCAATTTTCTGGGTTCTCAGGAGAGGGCTTTGGGGATAAGGGACTGGCTGGAATCACAGGGCCACGAGTATATTGTCACTGATGACAAGGAAGGACCAAATTGTGAACTAGAGAAACACATTGAAGATCTTCATGTTCTCATAACAACCCCGTTCCACCCTGCCTATGTCACGGCTGAACGGATCAAAAAGGCCAAGAATTTGGAACTGCTTCTAACCGCTGGAATTGGCTCTGATCACATTGATCTGAAAGCTGCAGCTGCTGCTGGTTTGACAGTGGCAGAGGTCACGGGAAGCAATGTGGTTTCGGTTGCAGAAGACGAGCTCATGAGAATCCTCATTCTCGTCCGCAACTTCGTACCTGGGTATCAGCAGATTGTAACCGGGGAATGGAACGTTGCAGGTATTGCCCACAGAGCTTATGATCTCGAAGGAAAGACGGTGGGGACGGTTGGTGCTGGACGTATTGGTAGGCTTTTGCTCCAAAGGTTGAAGCCCTTCAACTGCAATCTTCTCTATCATGATCGCGTCAAGATTGACCCCGAATTGGAGCAACAGACTGGGGCAAAGTTCGAGGAGGATCTGGATGCAATGCTTCCGAAATGTGATGTTATCGTTGTCAACACACCACTTACTGAAAAAACAAGAGGACTGTTTGACAAAGAAAGAATTGCGAAGTGTAAGAAGGGAGTCCTGATCGTTAACAATGCTCGTGGAGCAATCATGGACACGCAGGCTGTTGTCGATGCTTGCTCCAGCGGACACATTGCAGGTTACAGTGGTGATGTTTGGAACCCACAACCAGCTCCAAAAGACCATCCATGGCGATACATGCCGAACCATGCTATGACCCCTCATATATCCGGTACCACAATTGACGCACAGTTGCGTTATGCTGCTGGGACGAAGGATATGCTTGACAGGTACTTCAAGGGAGAAGAATTTCCAGCACAAAACTACATTGTCAAGGACGGTAAACTAGCAAGCCAGTACCAGTAG

Functional Annotation

Gene Ontology

Molecular Function
Biological Process
Cellular Component

GO:0005575 GO:0005622 GO:0005623 GO:0005737 GO:0005739 GO:0008150 GO:0009507 GO:0009536 GO:0009579 GO:0010035 GO:0010038 GO:0042221 GO:0043226 GO:0043227 GO:0043229 GO:0043231 GO:0044424 GO:0044444 GO:0044464 GO:0046686 GO:0050896

KEGG Pathways

Metabolic & Signaling

ko00630 ko00680 ko01100 ko01120 ko01200 map00630 map00680 map01100 map01120 map01200

Pfam Domains

Protein Families

2-Hacid_dh 2-Hacid_dh_C

Protein Analysis

386

Amino Acids

42.12

Weight (kDa)

6.51

Isoelectric Point (pI)

28.73

Instability Index

Protein Domains (Pfam)

Domain Name	Pfam ID	Position	E-value	Description
2-Hacid_dh	PF00389	70 - 367	9.8e-16	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
2-Hacid_dh_C	PF02826	163 - 341	2.7e-51	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain

Hydrophobicity Profile (Kyte-Doolittle)

AI Structure Prediction Report

Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter

Style Settings

Font Size (px)

Line Width

Align Labels (Cladogram)

Image

Tree File

Tip: Beautify your tree with professional tools

Download the Full Tree (.nwk) file, then upload it to any of the following tools to customize colors, fonts, annotations, clades, and branch support.

Publication-ready

iTOL Interactive Tree Of Life · Most popular EvolView Flexible annotations MEGA Desktop phylogenetics suite FigTree Desktop tree editor

Orthologous Genes (Group: OG0007870)

Species	Orthologous Gene IDs
arabidopsis_thaliana	AT5G14780 AT5G14780 AT5G14780
fragaria_vesca	FvH4_6g50630
malus_domestica	MD09G1034400.v1.1 MD17G1034800.v1.1
prunus_persica	Prupe.3G284000_v2.0.a1 Prupe.3G284000_v2.0.a1 Prupe.3G284000_v2.0.a1 Prupe.3G284000_v2.0.a1
pyrus_communis	pycom111g02730 pycom17g03210
rosa_chinensis	RchiOBHm_Chr2g0171431
rosa_laevigata	RLG00000022013
rosa_multiflora	Rmu_sc0007646.1_g000006 Rmu_sc0027265.1_g000001 Rmu_sc0030144.1_g000002
rosa_roxburghii	Rroxscaffold_2G00080660
rosa_rugosa	Rorug02G0554200
rosa_samantha	Rh2AG628500 Rh2CG607600 Rh2DG650000 Rh2DG656000
rosa_wichuraiana	Rw2G052060

Restriction Enzyme Sites

1 / 10

Enzyme	Recognition Site	Cut Count	Positions (bp)
Acc36I	ACCTGC	2 cut(s)	551, 920
Acc65I	GGTACC	1 cut(s)	1025
AccB1I	GGYRCC	2 cut(s)	84, 1025
AccII	CGCG	1 cut(s)	687
AciI	CCGC	3 cut(s)	378, 508, 918
AclI	AACGTT	1 cut(s)	555
AclWI	GGATC	2 cut(s)	350, 747
AcsI	RAATTY	2 cut(s)	358, 1100
AfaI	GTAC	4 cut(s)	519, 1027, 1085, 1151
AfiI	CCNNNNNNNGG	2 cut(s)	549, 706
AgsI	TTSAA	5 cut(s)	157, 284, 652, 661, 1090
AjnI	CCWGG	2 cut(s)	80, 520
AluBI	AGCT	7 cut(s)	38, 57, 413, 419, 484, 578, 965
AluI	AGCT	7 cut(s)	38, 57, 413, 419, 484, 578, 965
Alw21I	GWGCWC	2 cut(s)	40, 486
AlwI	GGATC	2 cut(s)	350, 747
AlwNI	CAGNNNCTG	1 cut(s)	422
AoxI	GGCC	2 cut(s)	220, 351
ApeKI	GCWGC	5 cut(s)	413, 416, 419, 422, 1055
ApoI	RAATTY	2 cut(s)	358, 1100
Asp700I	GAANNNNTTC	4 cut(s)	288, 369, 656, 1101
Asp718I	GGTACC	1 cut(s)	1025
AspS9I	GGNCC	2 cut(s)	220, 254
AsuC2I	CCSGG	1 cut(s)	544
AsuHPI	GGTGA	2 cut(s)	70, 953
AvaII	GGWCC	1 cut(s)	254
BaeI	ACNNNNGTAYC	2 cut(s)	509, 542
BanI	GGYRCC	2 cut(s)	84, 1025
BanII	GRGCYC	2 cut(s)	40, 486
BauI	CACGAG	2 cut(s)	224, 870
BbsI	GAAGAC	1 cut(s)	483
Bbv12I	GWGCWC	2 cut(s)	40, 486
BbvI	GCAGC	5 cut(s)	400, 406, 409, 428, 1042
BccI	CCATC	1 cut(s)	984
BceAI	ACGGC	1 cut(s)	348
BcgI	CGANNNNNNTGC	2 cut(s)	1054, 1088
BciT130I	CCWGG	2 cut(s)	82, 522
BclI	TGATCA	1 cut(s)	394
BcnI	CCSGG	1 cut(s)	544
BfaI	CTAG	2 cut(s)	269, 1139
BfmI	CTRYAG	2 cut(s)	27, 414
BfuAI	ACCTGC	2 cut(s)	551, 920
BglII	AGATCT	1 cut(s)	286
BisI	GCNGC	5 cut(s)	414, 417, 420, 423, 1056
BlpI	GCTNAGC	1 cut(s)	58
BlsI	GCNGC	5 cut(s)	415, 418, 421, 424, 1057
Bme1390I	CCNGG	3 cut(s)	82, 522, 544
Bme18I	GGWCC	1 cut(s)	254
BmgT120I	GGNCC	2 cut(s)	220, 254
BmiI	GGNNCC	3 cut(s)	86, 953, 1027
BmrFI	CCNGG	3 cut(s)	82, 522, 544
BmrI	ACTGGG	1 cut(s)	729
BmsI	GCATC	4 cut(s)	71, 104, 736, 895
BmuI	ACTGGG	1 cut(s)	729
BpiI	GAAGAC	1 cut(s)	483
BpmI	CTGGAG	1 cut(s)	898
Bpu1102I	GCTNAGC	1 cut(s)	58
BpuMI	CCSGG	1 cut(s)	544
BsaJI	CCNNGG	3 cut(s)	521, 543, 980
BsaWI	WCCGGW	1 cut(s)	1022
Bsc4I	CCNNNNNNNGG	2 cut(s)	549, 706
Bse1I	ACTGG	4 cut(s)	209, 724, 1147, 1153
Bse3DI	GCAATG	3 cut(s)	463, 756, 924
BseBI	CCWGG	2 cut(s)	82, 522
BseDI	CCNNGG	3 cut(s)	521, 543, 980
BseGI	GGATG	2 cut(s)	751, 976
BseLI	CCNNNNNNNGG	2 cut(s)	549, 706
BseMI	GCAATG	3 cut(s)	463, 756, 924
BseMII	CTCAG	2 cut(s)	72, 191
BseNI	ACTGG	4 cut(s)	209, 724, 1147, 1153
BseRI	GAGGAG	1 cut(s)	749
BseXI	GCAGC	5 cut(s)	400, 406, 409, 428, 1042
BseYI	CCCAGC	1 cut(s)	1058
Bsh1236I	CGCG	1 cut(s)	687
BshFI	GGCC	2 cut(s)	222, 353
BshNI	GGYRCC	2 cut(s)	84, 1025
BsiHKAI	GWGCWC	2 cut(s)	40, 486
BsiSI	CCGG	2 cut(s)	543, 1023
BslFI	GGGAC	3 cut(s)	215, 619, 1075
BslI	CCNNNNNNNGG	2 cut(s)	549, 706
BsmFI	GGGAC	3 cut(s)	215, 619, 1075
BsnI	GGCC	2 cut(s)	222, 353
Bsp1286I	GDGCHC	2 cut(s)	40, 486
Bsp143I	GATC	8 cut(s)	286, 342, 394, 403, 583, 682, 739, 855
Bsp1720I	GCTNAGC	1 cut(s)	58
Bsp19I	CCATGG	1 cut(s)	980
BspACI	CCGC	3 cut(s)	378, 508, 918
BspANI	GGCC	2 cut(s)	222, 353
BspCNI	CTCAG	2 cut(s)	71, 190
BspFNI	CGCG	1 cut(s)	687
BspHI	TCATGA	2 cut(s)	486, 679
BspLI	GGNNCC	3 cut(s)	86, 953, 1027
BspMAI	CTGCAG	2 cut(s)	31, 418
BspMI	ACCTGC	2 cut(s)	551, 920
BspPI	GGATC	2 cut(s)	350, 747
BspT107I	GGYRCC	2 cut(s)	84, 1025
BsrDI	GCAATG	3 cut(s)	463, 756, 924
BsrI	ACTGG	4 cut(s)	209, 724, 1147, 1153
BssECI	CCNNGG	3 cut(s)	521, 543, 980
BssMI	GATC	8 cut(s)	286, 342, 394, 403, 583, 682, 739, 855
BssSI	CACGAG	2 cut(s)	224, 870
BssT1I	CCWWGG	1 cut(s)	980
Bst2BI	CACGAG	2 cut(s)	224, 870
Bst2UI	CCWGG	2 cut(s)	82, 522
Bst4CI	ACNGT	7 cut(s)	436, 601, 610, 813, 938, 1044, 1133
BstAPI	GCANNNNNTGC	2 cut(s)	422, 566
BstC8I	GCNNGC	3 cut(s)	894, 910, 1144
BstDEI	CTNAG	2 cut(s)	58, 177
BstDSI	CCRYGG	1 cut(s)	980
BstF5I	GGATG	2 cut(s)	751, 976
BstFNI	CGCG	1 cut(s)	687
BstKTI	GATC	8 cut(s)	289, 345, 397, 406, 586, 685, 742, 858
BstMBI	GATC	8 cut(s)	286, 342, 394, 403, 583, 682, 739, 855
BstMWI	GCNNNNNNNGC	7 cut(s)	35, 419, 422, 566, 575, 875, 991
BstNI	CCWGG	2 cut(s)	82, 522
BstNSI	RCATGY	1 cut(s)	994
BstSCI	CCNGG	3 cut(s)	80, 520, 542
BstSFI	CTRYAG	2 cut(s)	27, 414
BstUI	CGCG	1 cut(s)	687
BstV1I	GCAGC	5 cut(s)	400, 406, 409, 428, 1042
BstV2I	GAAGAC	1 cut(s)	483
BstX2I	RGATCY	2 cut(s)	286, 739
BstXI	CCANNNNNNTGG	3 cut(s)	98, 169, 361
BstYI	RGATCY	2 cut(s)	286, 739
BsuRI	GGCC	2 cut(s)	222, 353
BtgI	CCRYGG	1 cut(s)	980
BtsCI	GGATG	2 cut(s)	751, 976
BtsIMutI	CAGTG	3 cut(s)	237, 441, 943
BveI	ACCTGC	2 cut(s)	551, 920
Cac8I	GCNNGC	3 cut(s)	894, 910, 1144
CaiI	CAGNNNCTG	1 cut(s)	422
CciI	TCATGA	2 cut(s)	486, 679
Cfr13I	GGNCC	2 cut(s)	220, 254
CseI	GACGC	2 cut(s)	676, 1046
Csp6I	GTAC	4 cut(s)	518, 1026, 1084, 1150
CspCI	CAANNNNNGTGG	2 cut(s)	853, 888
CviAII	CATG	8 cut(s)	92, 293, 487, 680, 883, 981, 991, 1001
CviQI	GTAC	4 cut(s)	518, 1026, 1084, 1150
DdeI	CTNAG	2 cut(s)	58, 177
DpnI	GATC	8 cut(s)	288, 344, 396, 405, 585, 684, 741, 857
DpnII	GATC	8 cut(s)	286, 342, 394, 403, 583, 682, 739, 855
Ecl136II	GAGCTC	2 cut(s)	38, 484
Eco130I	CCWWGG	1 cut(s)	980
Eco24I	GRGCYC	2 cut(s)	40, 486
Eco47I	GGWCC	1 cut(s)	254
Eco53kI	GAGCTC	2 cut(s)	38, 484
EcoICRI	GAGCTC	2 cut(s)	38, 484
EcoRII	CCWGG	2 cut(s)	80, 520
EcoT14I	CCWWGG	1 cut(s)	980
EcoT22I	ATGCAT	1 cut(s)	97
EcoT38I	GRGCYC	2 cut(s)	40, 486
ErhI	CCWWGG	1 cut(s)	980
FaeI	CATG	8 cut(s)	95, 296, 490, 683, 886, 984, 994, 1004
FaqI	GGGAC	3 cut(s)	215, 619, 1075
FatI	CATG	8 cut(s)	91, 292, 486, 679, 882, 980, 990, 1000
FbaI	TGATCA	1 cut(s)	394
Fnu4HI	GCNGC	5 cut(s)	414, 417, 420, 423, 1056
FokI	GGATG	2 cut(s)	758, 963
FriOI	GRGCYC	2 cut(s)	40, 486
Fsp4HI	GCNGC	5 cut(s)	414, 417, 420, 423, 1056
FspBI	CTAG	2 cut(s)	269, 1139
GluI	GCNGC	5 cut(s)	414, 417, 420, 423, 1056
GsaI	CCCAGC	1 cut(s)	1062
GsuI	CTGGAG	1 cut(s)	898
HaeIII	GGCC	2 cut(s)	222, 353
HapII	CCGG	2 cut(s)	543, 1023
HgaI	GACGC	2 cut(s)	676, 1046
Hin1II	CATG	8 cut(s)	95, 296, 490, 683, 886, 984, 994, 1004
HincII	GTYRAC	2 cut(s)	781, 862
HindII	GTYRAC	2 cut(s)	781, 862
HinfI	GANTC	3 cut(s)	212, 492, 849
HpaI	GTTAAC	1 cut(s)	862
HpaII	CCGG	2 cut(s)	543, 1023
HphI	GGTGA	2 cut(s)	70, 953
Hpy166II	GTNNAC	4 cut(s)	266, 781, 862, 1136
Hpy188I	TCNGA	3 cut(s)	394, 408, 759
Hpy188III	TCNNGA	8 cut(s)	51, 179, 487, 587, 680, 691, 743, 853
Hpy8I	GTNNAC	4 cut(s)	266, 781, 862, 1136
HpyAV	CCTTC	5 cut(s)	245, 584, 667, 838, 1060
HpyCH4III	ACNGT	7 cut(s)	436, 601, 610, 813, 938, 1044, 1133
HpyCH4IV	ACGT	2 cut(s)	555, 622
HpyCH4V	TGCA	9 cut(s)	29, 95, 149, 416, 473, 560, 666, 749, 929
HpyF10VI	GCNNNNNNNGC	7 cut(s)	35, 419, 422, 566, 575, 875, 991
HpyF3I	CTNAG	2 cut(s)	58, 177
HpySE526I	ACGT	2 cut(s)	555, 622
Hsp92II	CATG	8 cut(s)	95, 296, 490, 683, 886, 984, 994, 1004
KpnI	GGTACC	1 cut(s)	1029
Ksp22I	TGATCA	1 cut(s)	394
KspAI	GTTAAC	1 cut(s)	862
Kzo9I	GATC	8 cut(s)	286, 342, 394, 403, 583, 682, 739, 855
LmnI	GCTCC	5 cut(s)	645, 709, 875, 917, 970
Lsp1109I	GCAGC	5 cut(s)	400, 406, 409, 428, 1042
LweI	GCATC	4 cut(s)	71, 104, 736, 895
MaeI	CTAG	2 cut(s)	269, 1139
MaeII	ACGT	2 cut(s)	555, 622
MaeIII	GTNAC	5 cut(s)	235, 328, 445, 538, 932
MalI	GATC	8 cut(s)	288, 344, 396, 405, 585, 684, 741, 857
MboI	GATC	8 cut(s)	286, 342, 394, 403, 583, 682, 739, 855
MboII	GAAGA	5 cut(s)	281, 296, 488, 662, 1109
MfeI	CAATTG	1 cut(s)	1032
MflI	RGATCY	2 cut(s)	286, 739
MhlI	GDGCHC	2 cut(s)	40, 486
MluCI	AATT	9 cut(s)	152, 163, 259, 358, 384, 704, 828, 1032, 1100
MlyI	GAGTC	1 cut(s)	858
MnlI	CCTC	8 cut(s)	98, 177, 436, 506, 727, 730, 800, 1023
Mph1103I	ATGCAT	1 cut(s)	97
MroXI	GAANNNNTTC	4 cut(s)	288, 369, 656, 1101
MseI	TTAA	1 cut(s)	861
MslI	CAYNNNNRTG	1 cut(s)	90
MspA1I	CMGCKG	3 cut(s)	380, 419, 918
MspI	CCGG	2 cut(s)	543, 1023
MspR9I	CCNGG	3 cut(s)	82, 522, 544
MunI	CAATTG	1 cut(s)	1032
MvaI	CCWGG	2 cut(s)	82, 522
MvnI	CGCG	1 cut(s)	687
MwoI	GCNNNNNNNGC	7 cut(s)	35, 419, 422, 566, 575, 875, 991
NciI	CCSGG	1 cut(s)	544
NcoI	CCATGG	1 cut(s)	980
NdeII	GATC	8 cut(s)	286, 342, 394, 403, 583, 682, 739, 855
NlaIII	CATG	8 cut(s)	95, 296, 490, 683, 886, 984, 994, 1004
NlaIV	GGNNCC	3 cut(s)	86, 953, 1027
NmuCI	GTSAC	3 cut(s)	235, 328, 445
NsiI	ATGCAT	1 cut(s)	97
NspI	RCATGY	1 cut(s)	994
PagI	TCATGA	2 cut(s)	486, 679
PdmI	GAANNNNTTC	4 cut(s)	288, 369, 656, 1101
PfeI	GAWTC	2 cut(s)	212, 492
PkrI	GCNGC	5 cut(s)	415, 418, 421, 424, 1057
PleI	GAGTC	1 cut(s)	857
PpsI	GAGTC	1 cut(s)	857
Psp124BI	GAGCTC	2 cut(s)	40, 486
Psp1406I	AACGTT	1 cut(s)	555
Psp6I	CCWGG	2 cut(s)	80, 520
PspFI	CCCAGC	1 cut(s)	1058
PspGI	CCWGG	2 cut(s)	80, 520
PspN4I	GGNNCC	3 cut(s)	86, 953, 1027
PspPI	GGNCC	2 cut(s)	220, 254
PstI	CTGCAG	2 cut(s)	31, 418
PstNI	CAGNNNCTG	1 cut(s)	422
PsuI	RGATCY	2 cut(s)	286, 739
PvuII	CAGCTG	1 cut(s)	419
RsaI	GTAC	4 cut(s)	519, 1027, 1085, 1151
RsaNI	GTAC	4 cut(s)	518, 1026, 1084, 1150
RseI	CAYNNNNRTG	1 cut(s)	90
SacI	GAGCTC	2 cut(s)	40, 486
SaqAI	TTAA	1 cut(s)	861
SatI	GCNGC	5 cut(s)	414, 417, 420, 423, 1056
Sau3AI	GATC	8 cut(s)	286, 342, 394, 403, 583, 682, 739, 855
Sau96I	GGNCC	2 cut(s)	220, 254
SchI	GAGTC	1 cut(s)	858
ScrFI	CCNGG	3 cut(s)	82, 522, 544
SduI	GDGCHC	2 cut(s)	40, 486
SfaNI	GCATC	4 cut(s)	71, 104, 736, 895
SfcI	CTRYAG	2 cut(s)	27, 414
SinI	GGWCC	1 cut(s)	254
SmiMI	CAYNNNNRTG	1 cut(s)	90
Sse9I	AATT	9 cut(s)	152, 163, 259, 358, 384, 704, 828, 1032, 1100
SsiI	CCGC	3 cut(s)	378, 508, 918
SspMI	CTAG	2 cut(s)	269, 1139
SstI	GAGCTC	2 cut(s)	40, 486
StyD4I	CCNGG	3 cut(s)	80, 520, 542
StyI	CCWWGG	1 cut(s)	980
TaaI	ACNGT	7 cut(s)	436, 601, 610, 813, 938, 1044, 1133
TaiI	ACGT	2 cut(s)	558, 625
TaqI	TCGA	4 cut(s)	34, 588, 732, 903
TasI	AATT	9 cut(s)	152, 163, 259, 358, 384, 704, 828, 1032, 1100
TfiI	GAWTC	2 cut(s)	212, 492
Tru1I	TTAA	1 cut(s)	861
Tru9I	TTAA	1 cut(s)	861
TscAI	CASTG	3 cut(s)	244, 441, 943
TseFI	GTSAC	3 cut(s)	235, 328, 445
TseI	GCWGC	5 cut(s)	413, 416, 419, 422, 1055
Tsp45I	GTSAC	3 cut(s)	235, 328, 445
TspDTI	ATGAA	2 cut(s)	36, 281
TspGWI	ACGGA	1 cut(s)	355
TspRI	CASTG	3 cut(s)	244, 441, 943
VpaK11BI	GGWCC	1 cut(s)	254
XapI	RAATTY	2 cut(s)	358, 1100
XceI	RCATGY	1 cut(s)	994
XcmI	CCANNNNNNNNNTGG	1 cut(s)	98
XmnI	GAANNNNTTC	4 cut(s)	288, 369, 656, 1101
XspI	CTAG	2 cut(s)	269, 1139
Zsp2I	ATGCAT	1 cut(s)	97

Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.