The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins. Some of these proteins have been shown both in vivo and in vitro to have ubiquitin E3 ligase activity.
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| Species | Orthologous Gene IDs |
|---|---|
| arabidopsis_thaliana | AT5G60580 AT5G60580 AT5G60580 AT5G60580 |
| fragaria_vesca | FvH4_3g32510 FvH4_3g32510 FvH4_3g32510 |
| malus_domestica | MD03G1116800.v1.1 MD11G1134800.v1.1 |
| prunus_persica | Prupe.6G100700_v2.0.a1 Prupe.6G100700_v2.0.a1 |
| pyrus_communis | pycom11g11190 |
| rosa_chinensis | RchiOBHm_Chr5g0059571 |
| rosa_laevigata | RLG00000035303 |
| rosa_multiflora | Rmu_sc0001217.1_g000001 Rmu_sc0004068.1_g000005 |
| rosa_roxburghii | Rroxscaffold_1G00021040 |
| rosa_rugosa | Rorug05G0323100 Rorug05G0323200 |
| rosa_samantha | Rh5AG387800 Rh5BG399800 Rh5CG424000 Rh5DG416100 |
| rosa_wichuraiana | Rw5G036570 |
| Enzyme | Recognition Site | Cut Count | Positions (bp) |
|---|---|---|---|
| AciI | CCGC | 1 cut(s) | 1436 |
| AclWI | GGATC | 1 cut(s) | 316 |
| AcsI | RAATTY | 4 cut(s) | 64, 265, 816, 993 |
| AcuI | CTGAAG | 4 cut(s) | 147, 309, 405, 816 |
| AdeI | CACNNNGTG | 1 cut(s) | 566 |
| AfaI | GTAC | 5 cut(s) | 615, 639, 1077, 1150, 1188 |
| AfiI | CCNNNNNNNGG | 5 cut(s) | 255, 465, 504, 751, 859 |
| AgsI | TTSAA | 9 cut(s) | 69, 107, 186, 465, 594, 702, 830, 968, 998 |
| AjnI | CCWGG | 4 cut(s) | 171, 280, 313, 1131 |
| AjuI | GAANNNNNNNTTGG | 4 cut(s) | 526, 558, 739, 771 |
| AluBI | AGCT | 8 cut(s) | 329, 353, 387, 419, 487, 1010, 1129, 1443 |
| AluI | AGCT | 8 cut(s) | 329, 353, 387, 419, 487, 1010, 1129, 1443 |
| Alw21I | GWGCWC | 1 cut(s) | 1012 |
| Alw26I | GTCTC | 2 cut(s) | 842, 1199 |
| AlwI | GGATC | 1 cut(s) | 316 |
| AlwNI | CAGNNNCTG | 3 cut(s) | 557, 641, 1132 |
| Ama87I | CYCGRG | 1 cut(s) | 708 |
| AoxI | GGCC | 1 cut(s) | 316 |
| ApeKI | GCWGC | 1 cut(s) | 1126 |
| ApoI | RAATTY | 4 cut(s) | 64, 265, 816, 993 |
| Asp700I | GAANNNNTTC | 1 cut(s) | 388 |
| AspA2I | CCTAGG | 1 cut(s) | 254 |
| AspS9I | GGNCC | 1 cut(s) | 317 |
| AsuC2I | CCSGG | 2 cut(s) | 499, 1351 |
| AsuHPI | GGTGA | 6 cut(s) | 303, 794, 857, 887, 890, 1237 |
| AvaI | CYCGRG | 1 cut(s) | 708 |
| AvrII | CCTAGG | 1 cut(s) | 254 |
| BanII | GRGCYC | 1 cut(s) | 1012 |
| BbsI | GAAGAC | 3 cut(s) | 114, 204, 792 |
| Bbv12I | GWGCWC | 1 cut(s) | 1012 |
| BbvCI | CCTCAGC | 1 cut(s) | 42 |
| BbvI | GCAGC | 1 cut(s) | 1138 |
| BccI | CCATC | 4 cut(s) | 667, 1138, 1395, 1407 |
| BcgI | CGANNNNNNTGC | 2 cut(s) | 211, 245 |
| BciT130I | CCWGG | 4 cut(s) | 173, 282, 315, 1133 |
| BciVI | GTATCC | 1 cut(s) | 1049 |
| BclI | TGATCA | 1 cut(s) | 1036 |
| BcnI | CCSGG | 2 cut(s) | 499, 1351 |
| BcoDI | GTCTC | 2 cut(s) | 842, 1199 |
| BfaI | CTAG | 3 cut(s) | 255, 416, 824 |
| BfmI | CTRYAG | 2 cut(s) | 435, 811 |
| BfuI | GTATCC | 1 cut(s) | 1049 |
| BisI | GCNGC | 1 cut(s) | 1127 |
| BlnI | CCTAGG | 1 cut(s) | 254 |
| BlpI | GCTNAGC | 1 cut(s) | 1439 |
| BlsI | GCNGC | 1 cut(s) | 1128 |
| Bme1390I | CCNGG | 6 cut(s) | 173, 282, 315, 499, 1133, 1351 |
| BmeT110I | CYCGRG | 1 cut(s) | 708 |
| BmgT120I | GGNCC | 1 cut(s) | 317 |
| BmiI | GGNNCC | 2 cut(s) | 286, 319 |
| BmrFI | CCNGG | 6 cut(s) | 173, 282, 315, 499, 1133, 1351 |
| BmrI | ACTGGG | 1 cut(s) | 1199 |
| BmsI | GCATC | 6 cut(s) | 219, 283, 766, 933, 1036, 1262 |
| BmuI | ACTGGG | 1 cut(s) | 1199 |
| BpiI | GAAGAC | 3 cut(s) | 114, 204, 792 |
| BpmI | CTGGAG | 2 cut(s) | 194, 1173 |
| Bpu10I | CCTNAGC | 1 cut(s) | 42 |
| Bpu1102I | GCTNAGC | 1 cut(s) | 1439 |
| BpuEI | CTTGAG | 2 cut(s) | 1142, 1417 |
| BpuMI | CCSGG | 2 cut(s) | 499, 1351 |
| Bsa29I | ATCGAT | 1 cut(s) | 734 |
| BsaI | GGTCTC | 2 cut(s) | 842, 1199 |
| BsaJI | CCNNGG | 5 cut(s) | 73, 149, 254, 497, 1221 |
| BsaXI | ACNNNNNCTCC | 2 cut(s) | 1179, 1209 |
| Bsc4I | CCNNNNNNNGG | 5 cut(s) | 255, 465, 504, 751, 859 |
| Bse1I | ACTGG | 2 cut(s) | 1156, 1194 |
| Bse3DI | GCAATG | 1 cut(s) | 1371 |
| BseBI | CCWGG | 4 cut(s) | 173, 282, 315, 1133 |
| BseCI | ATCGAT | 1 cut(s) | 734 |
| BseDI | CCNNGG | 5 cut(s) | 73, 149, 254, 497, 1221 |
| BseGI | GGATG | 6 cut(s) | 145, 507, 515, 678, 730, 1202 |
| BseLI | CCNNNNNNNGG | 5 cut(s) | 255, 465, 504, 751, 859 |
| BseMI | GCAATG | 1 cut(s) | 1371 |
| BseMII | CTCAG | 2 cut(s) | 15, 33 |
| BseNI | ACTGG | 2 cut(s) | 1156, 1194 |
| BseRI | GAGGAG | 3 cut(s) | 520, 696, 1187 |
| BseXI | GCAGC | 1 cut(s) | 1138 |
| BsgI | GTGCAG | 1 cut(s) | 543 |
| BshFI | GGCC | 1 cut(s) | 318 |
| BshVI | ATCGAT | 1 cut(s) | 734 |
| BsiHKAI | GWGCWC | 1 cut(s) | 1012 |
| BsiHKCI | CYCGRG | 1 cut(s) | 708 |
| BsiSI | CCGG | 2 cut(s) | 499, 1350 |
| BslFI | GGGAC | 1 cut(s) | 460 |
| BslI | CCNNNNNNNGG | 5 cut(s) | 255, 465, 504, 751, 859 |
| BsmAI | GTCTC | 2 cut(s) | 842, 1199 |
| BsmFI | GGGAC | 1 cut(s) | 460 |
| BsmI | GAATGC | 1 cut(s) | 869 |
| BsnI | GGCC | 1 cut(s) | 318 |
| Bso31I | GGTCTC | 2 cut(s) | 842, 1199 |
| BsoBI | CYCGRG | 1 cut(s) | 708 |
| Bsp1286I | GDGCHC | 1 cut(s) | 1012 |
| Bsp143I | GATC | 3 cut(s) | 52, 308, 1036 |
| Bsp1720I | GCTNAGC | 1 cut(s) | 1439 |
| Bsp19I | CCATGG | 2 cut(s) | 149, 1221 |
| BspACI | CCGC | 1 cut(s) | 1436 |
| BspANI | GGCC | 1 cut(s) | 318 |
| BspCNI | CTCAG | 2 cut(s) | 16, 34 |
| BspDI | ATCGAT | 1 cut(s) | 734 |
| BspHI | TCATGA | 1 cut(s) | 49 |
| BspLI | GGNNCC | 2 cut(s) | 286, 319 |
| BspPI | GGATC | 1 cut(s) | 316 |
| BspQI | GCTCTTC | 1 cut(s) | 394 |
| BspTNI | GGTCTC | 2 cut(s) | 842, 1199 |
| BsrDI | GCAATG | 1 cut(s) | 1371 |
| BsrI | ACTGG | 2 cut(s) | 1156, 1194 |
| BssECI | CCNNGG | 5 cut(s) | 73, 149, 254, 497, 1221 |
| BssMI | GATC | 3 cut(s) | 52, 308, 1036 |
| BssT1I | CCWWGG | 4 cut(s) | 73, 149, 254, 1221 |
| Bst2UI | CCWGG | 4 cut(s) | 173, 282, 315, 1133 |
| Bst4CI | ACNGT | 2 cut(s) | 203, 751 |
| Bst6I | CTCTTC | 4 cut(s) | 328, 394, 795, 1176 |
| BstAPI | GCANNNNNTGC | 1 cut(s) | 1346 |
| BstC8I | GCNNGC | 5 cut(s) | 956, 1100, 1104, 1317, 1338 |
| BstDEI | CTNAG | 4 cut(s) | 24, 42, 368, 1439 |
| BstDSI | CCRYGG | 2 cut(s) | 149, 1221 |
| BstF5I | GGATG | 6 cut(s) | 145, 507, 515, 678, 730, 1202 |
| BstKTI | GATC | 3 cut(s) | 55, 311, 1039 |
| BstMAI | GTCTC | 2 cut(s) | 842, 1199 |
| BstMBI | GATC | 3 cut(s) | 52, 308, 1036 |
| BstMWI | GCNNNNNNNGC | 3 cut(s) | 493, 1016, 1346 |
| BstNI | CCWGG | 4 cut(s) | 173, 282, 315, 1133 |
| BstNSI | RCATGY | 1 cut(s) | 1102 |
| BstSCI | CCNGG | 6 cut(s) | 171, 280, 313, 497, 1131, 1349 |
| BstSFI | CTRYAG | 2 cut(s) | 435, 811 |
| BstV1I | GCAGC | 1 cut(s) | 1138 |
| BstV2I | GAAGAC | 3 cut(s) | 114, 204, 792 |
| Bsu15I | ATCGAT | 1 cut(s) | 734 |
| BsuI | GTATCC | 1 cut(s) | 1049 |
| BsuRI | GGCC | 1 cut(s) | 318 |
| BsuTUI | ATCGAT | 1 cut(s) | 734 |
| BtgI | CCRYGG | 2 cut(s) | 149, 1221 |
| BtsCI | GGATG | 6 cut(s) | 145, 507, 515, 678, 730, 1202 |
| Cac8I | GCNNGC | 5 cut(s) | 956, 1100, 1104, 1317, 1338 |
| CaiI | CAGNNNCTG | 3 cut(s) | 557, 641, 1132 |
| CciI | TCATGA | 1 cut(s) | 49 |
| Cfr13I | GGNCC | 1 cut(s) | 317 |
| ClaI | ATCGAT | 1 cut(s) | 734 |
| CsiI | ACCWGGT | 1 cut(s) | 280 |
| Csp6I | GTAC | 5 cut(s) | 614, 638, 1076, 1149, 1187 |
| CviAII | CATG | 7 cut(s) | 35, 50, 150, 563, 1099, 1207, 1222 |
| CviQI | GTAC | 5 cut(s) | 614, 638, 1076, 1149, 1187 |
| DdeI | CTNAG | 4 cut(s) | 24, 42, 368, 1439 |
| DpnI | GATC | 3 cut(s) | 54, 310, 1038 |
| DpnII | GATC | 3 cut(s) | 52, 308, 1036 |
| DraIII | CACNNNGTG | 1 cut(s) | 566 |
| Eam1104I | CTCTTC | 4 cut(s) | 328, 394, 795, 1176 |
| EarI | CTCTTC | 4 cut(s) | 328, 394, 795, 1176 |
| Ecl136II | GAGCTC | 1 cut(s) | 1010 |
| Eco130I | CCWWGG | 4 cut(s) | 73, 149, 254, 1221 |
| Eco24I | GRGCYC | 1 cut(s) | 1012 |
| Eco31I | GGTCTC | 2 cut(s) | 842, 1199 |
| Eco32I | GATATC | 2 cut(s) | 397, 621 |
| Eco53kI | GAGCTC | 1 cut(s) | 1010 |
| Eco57I | CTGAAG | 4 cut(s) | 147, 309, 405, 816 |
| Eco88I | CYCGRG | 1 cut(s) | 708 |
| EcoICRI | GAGCTC | 1 cut(s) | 1010 |
| EcoO109I | RGGNCCY | 1 cut(s) | 317 |
| EcoRI | GAATTC | 2 cut(s) | 64, 993 |
| EcoRII | CCWGG | 4 cut(s) | 171, 280, 313, 1131 |
| EcoRV | GATATC | 2 cut(s) | 397, 621 |
| EcoT14I | CCWWGG | 4 cut(s) | 73, 149, 254, 1221 |
| EcoT22I | ATGCAT | 1 cut(s) | 1255 |
| EcoT38I | GRGCYC | 1 cut(s) | 1012 |
| ErhI | CCWWGG | 4 cut(s) | 73, 149, 254, 1221 |
| FaeI | CATG | 7 cut(s) | 38, 53, 153, 566, 1102, 1210, 1225 |
| FalI | AAGNNNNNCTT | 4 cut(s) | 867, 899, 1308, 1340 |
| FaqI | GGGAC | 1 cut(s) | 460 |
| FatI | CATG | 7 cut(s) | 34, 49, 149, 562, 1098, 1206, 1221 |
| FbaI | TGATCA | 1 cut(s) | 1036 |
| Fnu4HI | GCNGC | 1 cut(s) | 1127 |
| FokI | GGATG | 6 cut(s) | 132, 502, 514, 685, 737, 1189 |
| FriOI | GRGCYC | 1 cut(s) | 1012 |
| Fsp4HI | GCNGC | 1 cut(s) | 1127 |
| FspBI | CTAG | 3 cut(s) | 255, 416, 824 |
| GluI | GCNGC | 1 cut(s) | 1127 |
| GsuI | CTGGAG | 2 cut(s) | 194, 1173 |
| HaeIII | GGCC | 1 cut(s) | 318 |
| HapII | CCGG | 2 cut(s) | 499, 1350 |
| Hin1II | CATG | 7 cut(s) | 38, 53, 153, 566, 1102, 1210, 1225 |
| HincII | GTYRAC | 1 cut(s) | 646 |
| HindII | GTYRAC | 1 cut(s) | 646 |
| HinfI | GANTC | 5 cut(s) | 110, 554, 605, 677, 755 |
| HpaII | CCGG | 2 cut(s) | 499, 1350 |
| HphI | GGTGA | 6 cut(s) | 303, 794, 857, 887, 890, 1237 |
| Hpy166II | GTNNAC | 4 cut(s) | 97, 646, 881, 1187 |
| Hpy188I | TCNGA | 5 cut(s) | 196, 394, 424, 588, 796 |
| Hpy188III | TCNNGA | 8 cut(s) | 50, 56, 186, 274, 400, 759, 1040, 1121 |
| Hpy8I | GTNNAC | 4 cut(s) | 97, 646, 881, 1187 |
| HpyAV | CCTTC | 7 cut(s) | 192, 397, 419, 465, 708, 709, 833 |
| HpyCH4III | ACNGT | 2 cut(s) | 203, 751 |
| HpyF10VI | GCNNNNNNNGC | 3 cut(s) | 493, 1016, 1346 |
| HpyF3I | CTNAG | 4 cut(s) | 24, 42, 368, 1439 |
| Hsp92II | CATG | 7 cut(s) | 38, 53, 153, 566, 1102, 1210, 1225 |
| Ksp22I | TGATCA | 1 cut(s) | 1036 |
| Kzo9I | GATC | 3 cut(s) | 52, 308, 1036 |
| LguI | GCTCTTC | 1 cut(s) | 394 |
| LmnI | GCTCC | 3 cut(s) | 440, 1134, 1154 |
| Lsp1109I | GCAGC | 1 cut(s) | 1138 |
| LweI | GCATC | 6 cut(s) | 219, 283, 766, 933, 1036, 1262 |
| MabI | ACCWGGT | 1 cut(s) | 280 |
| MaeI | CTAG | 3 cut(s) | 255, 416, 824 |
| MaeIII | GTNAC | 4 cut(s) | 121, 526, 932, 979 |
| MalI | GATC | 3 cut(s) | 54, 310, 1038 |
| MboI | GATC | 3 cut(s) | 52, 308, 1036 |
| MfeI | CAATTG | 3 cut(s) | 81, 534, 1158 |
| MhlI | GDGCHC | 1 cut(s) | 1012 |
| MluCI | AATT | 9 cut(s) | 64, 81, 265, 534, 662, 693, 816, 993, 1158 |
| MlyI | GAGTC | 1 cut(s) | 104 |
| MmeI | TCCRAC | 2 cut(s) | 260, 435 |
| Mph1103I | ATGCAT | 1 cut(s) | 1255 |
| MroXI | GAANNNNTTC | 1 cut(s) | 388 |
| MseI | TTAA | 3 cut(s) | 375, 665, 1447 |
| MslI | CAYNNNNRTG | 1 cut(s) | 54 |
| MspI | CCGG | 2 cut(s) | 499, 1350 |
| MspR9I | CCNGG | 6 cut(s) | 173, 282, 315, 499, 1133, 1351 |
| MunI | CAATTG | 3 cut(s) | 81, 534, 1158 |
| Mva1269I | GAATGC | 1 cut(s) | 869 |
| MvaI | CCWGG | 4 cut(s) | 173, 282, 315, 1133 |
| MwoI | GCNNNNNNNGC | 3 cut(s) | 493, 1016, 1346 |
| NciI | CCSGG | 2 cut(s) | 499, 1351 |
| NcoI | CCATGG | 2 cut(s) | 149, 1221 |
| NdeII | GATC | 3 cut(s) | 52, 308, 1036 |
| NlaIII | CATG | 7 cut(s) | 38, 53, 153, 566, 1102, 1210, 1225 |
| NlaIV | GGNNCC | 2 cut(s) | 286, 319 |
| NmuCI | GTSAC | 1 cut(s) | 979 |
| NsiI | ATGCAT | 1 cut(s) | 1255 |
| NspI | RCATGY | 1 cut(s) | 1102 |
| PaeI | GCATGC | 1 cut(s) | 1102 |
| PaeR7I | CTCGAG | 1 cut(s) | 708 |
| PagI | TCATGA | 1 cut(s) | 49 |
| PciSI | GCTCTTC | 1 cut(s) | 394 |
| PctI | GAATGC | 1 cut(s) | 869 |
| PdmI | GAANNNNTTC | 1 cut(s) | 388 |
| PfeI | GAWTC | 4 cut(s) | 554, 605, 677, 755 |
| PkrI | GCNGC | 1 cut(s) | 1128 |
| PleI | GAGTC | 1 cut(s) | 104 |
| PpsI | GAGTC | 1 cut(s) | 104 |
| Psp124BI | GAGCTC | 1 cut(s) | 1012 |
| Psp6I | CCWGG | 4 cut(s) | 171, 280, 313, 1131 |
| PspGI | CCWGG | 4 cut(s) | 171, 280, 313, 1131 |
| PspN4I | GGNNCC | 2 cut(s) | 286, 319 |
| PspPI | GGNCC | 1 cut(s) | 317 |
| PspXI | VCTCGAGB | 1 cut(s) | 708 |
| PstNI | CAGNNNCTG | 3 cut(s) | 557, 641, 1132 |
| RsaI | GTAC | 5 cut(s) | 615, 639, 1077, 1150, 1188 |
| RsaNI | GTAC | 5 cut(s) | 614, 638, 1076, 1149, 1187 |
| RseI | CAYNNNNRTG | 1 cut(s) | 54 |
| SacI | GAGCTC | 1 cut(s) | 1012 |
| SapI | GCTCTTC | 1 cut(s) | 394 |
| SaqAI | TTAA | 3 cut(s) | 375, 665, 1447 |
| SatI | GCNGC | 1 cut(s) | 1127 |
| Sau3AI | GATC | 3 cut(s) | 52, 308, 1036 |
| Sau96I | GGNCC | 1 cut(s) | 317 |
| SchI | GAGTC | 1 cut(s) | 104 |
| ScrFI | CCNGG | 6 cut(s) | 173, 282, 315, 499, 1133, 1351 |
| SduI | GDGCHC | 1 cut(s) | 1012 |
| SexAI | ACCWGGT | 1 cut(s) | 280 |
| SfaNI | GCATC | 6 cut(s) | 219, 283, 766, 933, 1036, 1262 |
| SfcI | CTRYAG | 2 cut(s) | 435, 811 |
| Sfr274I | CTCGAG | 1 cut(s) | 708 |
| SlaI | CTCGAG | 1 cut(s) | 708 |
| SmiMI | CAYNNNNRTG | 1 cut(s) | 54 |
| SmlI | CTYRAG | 3 cut(s) | 708, 1121, 1396 |
| SmoI | CTYRAG | 3 cut(s) | 708, 1121, 1396 |
| SphI | GCATGC | 1 cut(s) | 1102 |
| Sse9I | AATT | 9 cut(s) | 64, 81, 265, 534, 662, 693, 816, 993, 1158 |
| SsiI | CCGC | 1 cut(s) | 1436 |
| SspMI | CTAG | 3 cut(s) | 255, 416, 824 |
| SstI | GAGCTC | 1 cut(s) | 1012 |
| StyD4I | CCNGG | 6 cut(s) | 171, 280, 313, 497, 1131, 1349 |
| StyI | CCWWGG | 4 cut(s) | 73, 149, 254, 1221 |
| TaaI | ACNGT | 2 cut(s) | 203, 751 |
| TaqI | TCGA | 8 cut(s) | 382, 399, 709, 734, 1006, 1012, 1379, 1389 |
| TasI | AATT | 9 cut(s) | 64, 81, 265, 534, 662, 693, 816, 993, 1158 |
| TatI | WGTACW | 2 cut(s) | 613, 1186 |
| TfiI | GAWTC | 4 cut(s) | 554, 605, 677, 755 |
| Tru1I | TTAA | 3 cut(s) | 375, 665, 1447 |
| Tru9I | TTAA | 3 cut(s) | 375, 665, 1447 |
| TseFI | GTSAC | 1 cut(s) | 979 |
| TseI | GCWGC | 1 cut(s) | 1126 |
| Tsp45I | GTSAC | 1 cut(s) | 979 |
| TspDTI | ATGAA | 4 cut(s) | 38, 134, 669, 1290 |
| TspGWI | ACGGA | 1 cut(s) | 613 |
| XapI | RAATTY | 4 cut(s) | 64, 265, 816, 993 |
| XceI | RCATGY | 1 cut(s) | 1102 |
| XhoI | CTCGAG | 1 cut(s) | 708 |
| XmaJI | CCTAGG | 1 cut(s) | 254 |
| XmnI | GAANNNNTTC | 1 cut(s) | 388 |
| XspI | CTAG | 3 cut(s) | 255, 416, 824 |
| Zsp2I | ATGCAT | 1 cut(s) | 1255 |