Basic Information

Type: gene

Biological Identity

Species

rosa_laevigata

Chromosome

Chr3

Orthogroup ID

OG0015278

Physical Location & Seq

Genomic Coordinates Reverse (-)

2395740 .. 2397235

Gene Structure 1496 bp

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UTR

Exon/CDS

Intron

Transcript / Protein ID

RLM00000010527

Sequence Viewer

CDS Protein Promoter (2k)

Length: 1203 bp

ATGAAGAAGCAGCTAGGATTACTGGTTTCGATGGCTGTGATGATGTACACGTGCCAAGCAGTTAGCAACCTCCACCCTGTGATCCTAATACCTGGAAATGGCGGGAATCAGTTGGAAGCGAGACTAACCCCGATTACAAGCCCAGTAGTTTGGTATGCAACCGTTGGTACCCGATTGAGAGGAACAAGGAGGGATAAAGATGATTACCACAATGCCCCTGGGGTTGAAACCAGAGTCCCCCACTTCGGGTCCATTCAGTCCCTTCTGTTCCTTGACCCCAATCTCAAGAAGATCACAACATACATGGCACCCCTAGTGGAATCATTGGAGAATATTGGCTATGTCGATGGCAAAACCATGTTCGGAGCTCCGTACGATTTTCGATATGGTTTAGCACCTAAAGACCACCAATCCCATGTTGGTTCCAAGTTCCTGAATGACCTAAAAGACTTGGTCGAAAAGGCCAGTAATTCTAATGGAGGAAAGCCGGTAATACTTGTCTCGCACAGCTTAGGAGGCCTCTTTGCTCTCCAACTTCTGAATCGAAACAAGCCCTCATGGCGCCAAAGGTTCATCAAACACTTCGTTGCACTCTCAGCACCGTGGGGTGGGACTGTGGACGAAATGCTCACCTTTGCTTCAGGGAACACACTAGGAGTGCCACTGGTGAATCCATTGCTCGTAAGAGAAGAGCAGAGGAGCTCAGAAAGCAACTTATGGCTAATGCCTAATCCTAGATTATTCAGGAGCAAAAAGCCAGTAGTGATCACCCCAGATGCTACATATTCAGCTCATAACATTCCCCAATTCCTCAATGACATTGGATTTCCCGAAGGAATTCATCCCTTCAAAACGCGCATTTTGGTCTTGATGGATCAGCTTGAAGCTCCTGGGGTGCCTCTTACTTGTGTTATTGGGACCGGTGTGAGGACAGCAGAGACTTTGTTCTATGACAAAAGAGGCTTTGATGAGCAACCGGAGATTGTTTACGGGGATGGAGATGGAACTGTGAACATGTTGAGCTTGTTAGGACATGAATCACTGTGGTCCAATTCGGAAAATCAAACCCTGAAAACGATTAGAGTTCCTGGGATGACTCATACCGAGATACTCAAAGATGATGGTGCACTTGGTGAAGTGGTTAGAGAAATCTCTGGAATTAATTCTCAGTTCATGTTTGTTGAGAATGCAAATGTGCAATGA

Functional Annotation

Gene Ontology

Molecular Function
Biological Process
Cellular Component

GO:0005575 GO:0005622 GO:0005623 GO:0005737 GO:0005773 GO:0005774 GO:0016020 GO:0031090 GO:0043226 GO:0043227 GO:0043229 GO:0043231 GO:0044422 GO:0044424 GO:0044437 GO:0044444 GO:0044446 GO:0044464 GO:0098588 GO:0098805

KEGG Pathways

Metabolic & Signaling

ko00564 ko04142 map00564 map04142

Pfam Domains

Protein Families

LCAT

Protein Analysis

401

Amino Acids

44.25

Weight (kDa)

6.84

Isoelectric Point (pI)

39.8

Instability Index

Protein Domains (Pfam)

Domain Name	Pfam ID	Position	E-value	Description
LCAT	PF02450	70 - 273	3.8e-37	Lecithin:cholesterol acyltransferase
Hydrolase_4	PF12146	142 - 192	5.6e-07	Serine aminopeptidase, S33

Hydrophobicity Profile (Kyte-Doolittle)

AI Structure Prediction Report

Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter

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Align Labels (Cladogram)

Image

Tree File

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Publication-ready

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Orthologous Genes (Group: OG0015278)

Species	Orthologous Gene IDs
arabidopsis_thaliana	AT1G27480
fragaria_vesca	FvH4_2g32820 FvH4_2g32820
prunus_persica	Prupe.1G420700_v2.0.a1
pyrus_communis	pycom08g06610
rosa_chinensis	RchiOBHm_Chr6g0309881
rosa_laevigata	RLG00000010527
rosa_multiflora	Rmu_sc0006780.1_g000001
rosa_roxburghii	Rroxscaffold_7G00159080
rosa_rugosa	Rorug06G0375600
rosa_samantha	Rh6AG489300 Rh6AG489400 Rh6BG498800 Rh6CG503600 Rh6DG489700
rosa_wichuraiana	Rw6G042590

Restriction Enzyme Sites

1 / 10

Enzyme	Recognition Site	Cut Count	Positions (bp)
Acc65I	GGTACC	1 cut(s)	167
AccB1I	GGYRCC	4 cut(s)	167, 307, 561, 895
AccII	CGCG	1 cut(s)	856
AciI	CCGC	1 cut(s)	102
AclWI	GGATC	2 cut(s)	76, 882
AcsI	RAATTY	1 cut(s)	837
AcuI	CTGAAG	1 cut(s)	624
AcvI	CACGTG	1 cut(s)	51
AcyI	GRCGYC	1 cut(s)	562
AdeI	CACNNNGTG	2 cut(s)	79, 1133
AfaI	GTAC	3 cut(s)	47, 169, 374
AfiI	CCNNNNNNNGG	5 cut(s)	98, 245, 246, 608, 927
AflIII	ACRYGT	2 cut(s)	48, 1014
AgeI	ACCGGT	1 cut(s)	920
AgsI	TTSAA	3 cut(s)	227, 850, 884
AjnI	CCWGG	4 cut(s)	91, 217, 889, 1087
AluBI	AGCT	8 cut(s)	13, 368, 510, 702, 791, 880, 887, 1023
AluI	AGCT	8 cut(s)	13, 368, 510, 702, 791, 880, 887, 1023
Alw21I	GWGCWC	3 cut(s)	370, 704, 1129
Alw26I	GTCTC	3 cut(s)	115, 505, 932
Alw44I	GTGCAC	1 cut(s)	1125
AlwI	GGATC	2 cut(s)	76, 882
AoxI	GGCC	2 cut(s)	462, 517
ApaLI	GTGCAC	1 cut(s)	1125
ApeKI	GCWGC	1 cut(s)	10
ApoI	RAATTY	1 cut(s)	837
AseI	ATTAAT	1 cut(s)	1161
AsiGI	ACCGGT	1 cut(s)	920
Asp700I	GAANNNNTTC	2 cut(s)	837, 1162
Asp718I	GGTACC	1 cut(s)	167
AspLEI	GCGC	2 cut(s)	564, 858
AspS9I	GGNCC	3 cut(s)	249, 918, 1047
AsuHPI	GGTGA	4 cut(s)	622, 679, 760, 1145
AvaII	GGWCC	3 cut(s)	249, 918, 1047
BaeGI	GKGCMC	1 cut(s)	1129
BanI	GGYRCC	4 cut(s)	167, 307, 561, 895
BanII	GRGCYC	2 cut(s)	370, 704
BbrPI	CACGTG	1 cut(s)	51
Bbv12I	GWGCWC	3 cut(s)	370, 704, 1129
BbvI	GCAGC	1 cut(s)	22
BccI	CCATC	6 cut(s)	25, 341, 865, 989, 995, 1115
BciT130I	CCWGG	4 cut(s)	93, 219, 891, 1089
BclI	TGATCA	1 cut(s)	765
BcoDI	GTCTC	3 cut(s)	115, 505, 932
BfaI	CTAG	4 cut(s)	14, 314, 653, 735
BfoI	RGCGCY	1 cut(s)	565
BglI	GCCNNNNNGGC	1 cut(s)	559
BisI	GCNGC	1 cut(s)	11
BlsI	GCNGC	1 cut(s)	12
Bme1390I	CCNGG	4 cut(s)	93, 219, 891, 1089
Bme18I	GGWCC	3 cut(s)	249, 918, 1047
BmgT120I	GGNCC	3 cut(s)	249, 918, 1047
BmiI	GGNNCC	7 cut(s)	169, 250, 309, 424, 563, 897, 919
BmrFI	CCNGG	4 cut(s)	93, 219, 891, 1089
BmrI	ACTGGG	1 cut(s)	137
BmsI	GCATC	1 cut(s)	766
BmuI	ACTGGG	1 cut(s)	137
Bpu10I	CCTNAGC	1 cut(s)	511
BpuEI	CTTGAG	1 cut(s)	269
BsaAI	YACGTR	1 cut(s)	51
BsaHI	GRCGYC	1 cut(s)	562
BsaJI	CCNNGG	5 cut(s)	217, 218, 602, 890, 1088
BsaWI	WCCGGW	2 cut(s)	920, 976
Bsc4I	CCNNNNNNNGG	5 cut(s)	98, 245, 246, 608, 927
Bse118I	RCCGGY	2 cut(s)	487, 920
Bse1I	ACTGG	5 cut(s)	27, 143, 465, 669, 758
Bse3DI	GCAATG	1 cut(s)	674
BseBI	CCWGG	4 cut(s)	93, 219, 891, 1089
BseDI	CCNNGG	5 cut(s)	217, 218, 602, 890, 1088
BseGI	GGATG	3 cut(s)	841, 1000, 1098
BseLI	CCNNNNNNNGG	5 cut(s)	98, 245, 246, 608, 927
BseMI	GCAATG	1 cut(s)	674
BseMII	CTCAG	3 cut(s)	609, 717, 1181
BseNI	ACTGG	5 cut(s)	27, 143, 465, 669, 758
BseRI	GAGGAG	1 cut(s)	712
BseSI	GKGCMC	1 cut(s)	1129
BseXI	GCAGC	1 cut(s)	22
Bsh1236I	CGCG	1 cut(s)	856
BshFI	GGCC	2 cut(s)	464, 519
BshNI	GGYRCC	4 cut(s)	167, 307, 561, 895
BshTI	ACCGGT	1 cut(s)	920
BsiHKAI	GWGCWC	3 cut(s)	370, 704, 1129
BsiSI	CCGG	3 cut(s)	488, 921, 977
BsiWI	CGTACG	1 cut(s)	372
BslFI	GGGAC	4 cut(s)	221, 244, 625, 931
BslI	CCNNNNNNNGG	5 cut(s)	98, 245, 246, 608, 927
BsmAI	GTCTC	3 cut(s)	115, 505, 932
BsmFI	GGGAC	4 cut(s)	221, 244, 625, 931
BsmI	GAATGC	1 cut(s)	1192
BsnI	GGCC	2 cut(s)	464, 519
Bsp1286I	GDGCHC	3 cut(s)	370, 704, 1129
Bsp1407I	TGTACA	1 cut(s)	45
Bsp143I	GATC	4 cut(s)	81, 291, 765, 874
BspACI	CCGC	1 cut(s)	102
BspANI	GGCC	2 cut(s)	464, 519
BspCNI	CTCAG	3 cut(s)	608, 716, 1180
BspFNI	CGCG	1 cut(s)	856
BspLI	GGNNCC	7 cut(s)	169, 250, 309, 424, 563, 897, 919
BspPI	GGATC	2 cut(s)	76, 882
BspQI	GCTCTTC	1 cut(s)	684
BspT107I	GGYRCC	4 cut(s)	167, 307, 561, 895
BsrDI	GCAATG	1 cut(s)	674
BsrFI	RCCGGY	2 cut(s)	487, 920
BsrGI	TGTACA	1 cut(s)	45
BsrI	ACTGG	5 cut(s)	27, 143, 465, 669, 758
BssAI	RCCGGY	2 cut(s)	487, 920
BssECI	CCNNGG	5 cut(s)	217, 218, 602, 890, 1088
BssMI	GATC	4 cut(s)	81, 291, 765, 874
BssNI	GRCGYC	1 cut(s)	562
Bst2UI	CCWGG	4 cut(s)	93, 219, 891, 1089
Bst4CI	ACNGT	5 cut(s)	163, 603, 616, 1009, 1044
Bst6I	CTCTTC	1 cut(s)	684
BstACI	GRCGYC	1 cut(s)	562
BstAUI	TGTACA	1 cut(s)	45
BstBAI	YACGTR	1 cut(s)	51
BstDEI	CTNAG	4 cut(s)	511, 595, 703, 1167
BstDSI	CCRYGG	1 cut(s)	602
BstF5I	GGATG	3 cut(s)	841, 1000, 1098
BstFNI	CGCG	1 cut(s)	856
BstH2I	RGCGCY	1 cut(s)	565
BstHHI	GCGC	2 cut(s)	564, 858
BstKTI	GATC	4 cut(s)	84, 294, 768, 877
BstMAI	GTCTC	3 cut(s)	115, 505, 932
BstMBI	GATC	4 cut(s)	81, 291, 765, 874
BstMWI	GCNNNNNNNGC	4 cut(s)	516, 559, 596, 708
BstNI	CCWGG	4 cut(s)	93, 219, 891, 1089
BstNSI	RCATGY	1 cut(s)	1018
BstSCI	CCNGG	4 cut(s)	91, 217, 889, 1087
BstSLI	GKGCMC	1 cut(s)	1129
BstUI	CGCG	1 cut(s)	856
BstV1I	GCAGC	1 cut(s)	22
BstXI	CCANNNNNNTGG	1 cut(s)	150
BsuRI	GGCC	2 cut(s)	464, 519
BtgI	CCRYGG	1 cut(s)	602
BtsCI	GGATG	3 cut(s)	841, 1000, 1098
BtsIMutI	CAGTG	2 cut(s)	662, 1040
CfoI	GCGC	2 cut(s)	564, 858
Cfr10I	RCCGGY	2 cut(s)	487, 920
Cfr13I	GGNCC	3 cut(s)	249, 918, 1047
Csp6I	GTAC	3 cut(s)	46, 168, 373
CspAI	ACCGGT	1 cut(s)	920
CviAII	CATG	7 cut(s)	304, 358, 416, 558, 1015, 1034, 1174
CviQI	GTAC	3 cut(s)	46, 168, 373
DdeI	CTNAG	4 cut(s)	511, 595, 703, 1167
DinI	GGCGCC	1 cut(s)	563
DpnI	GATC	4 cut(s)	83, 293, 767, 876
DpnII	GATC	4 cut(s)	81, 291, 765, 874
DraIII	CACNNNGTG	2 cut(s)	79, 1133
Eam1104I	CTCTTC	1 cut(s)	684
EarI	CTCTTC	1 cut(s)	684
Ecl136II	GAGCTC	2 cut(s)	368, 702
Eco147I	AGGCCT	1 cut(s)	519
Eco24I	GRGCYC	2 cut(s)	370, 704
Eco47I	GGWCC	3 cut(s)	249, 918, 1047
Eco53kI	GAGCTC	2 cut(s)	368, 702
Eco57I	CTGAAG	1 cut(s)	624
Eco72I	CACGTG	1 cut(s)	51
EcoICRI	GAGCTC	2 cut(s)	368, 702
EcoRI	GAATTC	1 cut(s)	837
EcoRII	CCWGG	4 cut(s)	91, 217, 889, 1087
EcoT38I	GRGCYC	2 cut(s)	370, 704
EgeI	GGCGCC	1 cut(s)	563
EheI	GGCGCC	1 cut(s)	563
FaeI	CATG	7 cut(s)	307, 361, 419, 561, 1018, 1037, 1177
FaqI	GGGAC	4 cut(s)	221, 244, 625, 931
FatI	CATG	7 cut(s)	303, 357, 415, 557, 1014, 1033, 1173
FauI	CCCGC	1 cut(s)	95
FbaI	TGATCA	1 cut(s)	765
Fnu4HI	GCNGC	1 cut(s)	11
FokI	GGATG	3 cut(s)	828, 1007, 1105
FriOI	GRGCYC	2 cut(s)	370, 704
Fsp4HI	GCNGC	1 cut(s)	11
FspBI	CTAG	4 cut(s)	14, 314, 653, 735
GlaI	GCGC	2 cut(s)	563, 857
GluI	GCNGC	1 cut(s)	11
HaeII	RGCGCY	1 cut(s)	565
HaeIII	GGCC	2 cut(s)	464, 519
HapII	CCGG	3 cut(s)	488, 921, 977
HhaI	GCGC	2 cut(s)	564, 858
Hin1I	GRCGYC	1 cut(s)	562
Hin1II	CATG	7 cut(s)	307, 361, 419, 561, 1018, 1037, 1177
Hin6I	GCGC	2 cut(s)	562, 856
HinP1I	GCGC	2 cut(s)	562, 856
HinfI	GANTC	7 cut(s)	106, 234, 320, 541, 670, 1037, 1096
HpaII	CCGG	3 cut(s)	488, 921, 977
HphI	GGTGA	4 cut(s)	622, 679, 760, 1145
Hpy166II	GTNNAC	5 cut(s)	48, 619, 988, 1012, 1127
Hpy188I	TCNGA	4 cut(s)	365, 540, 706, 1057
Hpy188III	TCNNGA	6 cut(s)	286, 433, 745, 830, 868, 1155
Hpy8I	GTNNAC	5 cut(s)	48, 619, 988, 1012, 1127
HpyAV	CCTTC	3 cut(s)	272, 827, 856
HpyCH4III	ACNGT	5 cut(s)	163, 603, 616, 1009, 1044
HpyCH4IV	ACGT	1 cut(s)	50
HpyCH4V	TGCA	5 cut(s)	158, 590, 1127, 1190, 1198
HpyF10VI	GCNNNNNNNGC	4 cut(s)	516, 559, 596, 708
HpyF3I	CTNAG	4 cut(s)	511, 595, 703, 1167
HpySE526I	ACGT	1 cut(s)	50
Hsp92I	GRCGYC	1 cut(s)	562
Hsp92II	CATG	7 cut(s)	307, 361, 419, 561, 1018, 1037, 1177
HspAI	GCGC	2 cut(s)	562, 856
KasI	GGCGCC	1 cut(s)	561
KpnI	GGTACC	1 cut(s)	171
Ksp22I	TGATCA	1 cut(s)	765
Kzo9I	GATC	4 cut(s)	81, 291, 765, 874
LguI	GCTCTTC	1 cut(s)	684
LmnI	GCTCC	5 cut(s)	365, 373, 699, 747, 892
Lsp1109I	GCAGC	1 cut(s)	22
LweI	GCATC	1 cut(s)	766
MaeI	CTAG	4 cut(s)	14, 314, 653, 735
MaeII	ACGT	1 cut(s)	50
MalI	GATC	4 cut(s)	83, 293, 767, 876
MboI	GATC	4 cut(s)	81, 291, 765, 874
MboII	GAAGA	3 cut(s)	16, 301, 701
MhlI	GDGCHC	3 cut(s)	370, 704, 1129
MluCI	AATT	6 cut(s)	469, 806, 837, 1051, 1158, 1162
Mly113I	GGCGCC	1 cut(s)	562
MlyI	GAGTC	2 cut(s)	243, 1090
MmeI	TCCRAC	2 cut(s)	93, 556
MroXI	GAANNNNTTC	2 cut(s)	837, 1162
MseI	TTAA	1 cut(s)	1161
MspI	CCGG	3 cut(s)	488, 921, 977
MspR9I	CCNGG	4 cut(s)	93, 219, 891, 1089
Mva1269I	GAATGC	1 cut(s)	1192
MvaI	CCWGG	4 cut(s)	93, 219, 891, 1089
MvnI	CGCG	1 cut(s)	856
MwoI	GCNNNNNNNGC	4 cut(s)	516, 559, 596, 708
NarI	GGCGCC	1 cut(s)	562
NdeII	GATC	4 cut(s)	81, 291, 765, 874
NlaIII	CATG	7 cut(s)	307, 361, 419, 561, 1018, 1037, 1177
NlaIV	GGNNCC	7 cut(s)	169, 250, 309, 424, 563, 897, 919
NspI	RCATGY	1 cut(s)	1018
PasI	CCCWGGG	1 cut(s)	218
PceI	AGGCCT	1 cut(s)	519
PciI	ACATGT	1 cut(s)	1014
PciSI	GCTCTTC	1 cut(s)	684
PctI	GAATGC	1 cut(s)	1192
PdmI	GAANNNNTTC	2 cut(s)	837, 1162
PfeI	GAWTC	5 cut(s)	106, 320, 541, 670, 1037
Pfl23II	CGTACG	1 cut(s)	372
PflFI	GACNNNGTC	1 cut(s)	452
PinAI	ACCGGT	1 cut(s)	920
PkrI	GCNGC	1 cut(s)	12
PleI	GAGTC	2 cut(s)	242, 1090
PluTI	GGCGCC	1 cut(s)	565
PmaCI	CACGTG	1 cut(s)	51
PmlI	CACGTG	1 cut(s)	51
PpsI	GAGTC	2 cut(s)	242, 1090
Ppu21I	YACGTR	1 cut(s)	51
PscI	ACATGT	1 cut(s)	1014
PshBI	ATTAAT	1 cut(s)	1161
Psp124BI	GAGCTC	2 cut(s)	370, 704
Psp6I	CCWGG	4 cut(s)	91, 217, 889, 1087
PspCI	CACGTG	1 cut(s)	51
PspGI	CCWGG	4 cut(s)	91, 217, 889, 1087
PspLI	CGTACG	1 cut(s)	372
PspN4I	GGNNCC	7 cut(s)	169, 250, 309, 424, 563, 897, 919
PspPI	GGNCC	3 cut(s)	249, 918, 1047
PsyI	GACNNNGTC	1 cut(s)	452
RsaI	GTAC	3 cut(s)	47, 169, 374
RsaNI	GTAC	3 cut(s)	46, 168, 373
SacI	GAGCTC	2 cut(s)	370, 704
SapI	GCTCTTC	1 cut(s)	684
SaqAI	TTAA	1 cut(s)	1161
SatI	GCNGC	1 cut(s)	11
Sau3AI	GATC	4 cut(s)	81, 291, 765, 874
Sau96I	GGNCC	3 cut(s)	249, 918, 1047
SchI	GAGTC	2 cut(s)	243, 1090
ScrFI	CCNGG	4 cut(s)	93, 219, 891, 1089
SduI	GDGCHC	3 cut(s)	370, 704, 1129
SfaNI	GCATC	1 cut(s)	766
SfoI	GGCGCC	1 cut(s)	563
SinI	GGWCC	3 cut(s)	249, 918, 1047
SmlI	CTYRAG	1 cut(s)	284
SmoI	CTYRAG	1 cut(s)	284
Sse9I	AATT	6 cut(s)	469, 806, 837, 1051, 1158, 1162
SseBI	AGGCCT	1 cut(s)	519
SsiI	CCGC	1 cut(s)	102
SspDI	GGCGCC	1 cut(s)	561
SspI	AATATT	1 cut(s)	334
SspMI	CTAG	4 cut(s)	14, 314, 653, 735
SstI	GAGCTC	2 cut(s)	370, 704
StuI	AGGCCT	1 cut(s)	519
StyD4I	CCNGG	4 cut(s)	91, 217, 889, 1087
TaaI	ACNGT	5 cut(s)	163, 603, 616, 1009, 1044
TaiI	ACGT	1 cut(s)	53
TaqI	TCGA	5 cut(s)	29, 345, 382, 456, 544
TasI	AATT	6 cut(s)	469, 806, 837, 1051, 1158, 1162
TatI	WGTACW	1 cut(s)	45
TfiI	GAWTC	5 cut(s)	106, 320, 541, 670, 1037
Tru1I	TTAA	1 cut(s)	1161
Tru9I	TTAA	1 cut(s)	1161
TscAI	CASTG	2 cut(s)	669, 1047
TseI	GCWGC	1 cut(s)	10
TspDTI	ATGAA	5 cut(s)	17, 562, 830, 1050, 1162
TspGWI	ACGGA	1 cut(s)	360
TspRI	CASTG	2 cut(s)	669, 1047
Tth111I	GACNNNGTC	1 cut(s)	452
VneI	GTGCAC	1 cut(s)	1125
VpaK11BI	GGWCC	3 cut(s)	249, 918, 1047
VspI	ATTAAT	1 cut(s)	1161
XapI	RAATTY	1 cut(s)	837
XceI	RCATGY	1 cut(s)	1018
XcmI	CCANNNNNNNNNTGG	2 cut(s)	215, 416
XmnI	GAANNNNTTC	2 cut(s)	837, 1162
XspI	CTAG	4 cut(s)	14, 314, 653, 735

Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.