Basic Information

Type: gene

Biological Identity

Species

malus_domestica

Chromosome

Chr05

Orthogroup ID

OG0015822

Physical Location & Seq

Genomic Coordinates Reverse (-)

43234137 .. 43235528

Gene Structure 1392 bp

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UTR

Exon/CDS

Intron

Transcript / Protein ID

MD05G1298900.v1.1.491

Sequence Viewer

CDS Protein Promoter (2k)

Length: 1392 bp

ATGGAGGTGAAAAAAGGAAACATATTGATGCACAAGTACGAGGTGGGACGGTTGCTTGGAAAAGGGACATTTGCCAAGGTTTACCATGCACGGAACCTGAAGTCCGGCCAGAGCGTTGCAATTAAGATAATCGACAAGGAGAAGGTGCAGAAGGTCGGATTGATTGATCAGATCAAGAGGGAAATCTCCGTGATGCGCCTTGTGAGGCACCCGAATGTGGTTCAGCTCTTTGAGGTTATGGCCAGCAAGACCAAGATTTATTTTGCCATGGAGTACGTGAGAGGCGGGGAGCTTTTCAACAAGGTTGCCAAAGGGAAGCTTAAGGAAGATGTGGCAAGAAAATACTTTCAGCAACTGATTGGGGCTGTCGATTACTGCCACAGTCGAGGGGTCTATCACCGCGACATCAAGCCAGAGAATCTCTTGGTGGACGAGAATGGAAACCTCAAAGTTTCGGATTTTGGATTAAGCGCATTGTGGGAGTCTAGGGGACAAGATGGCCTCCTCCACACCACGTGTGGTACGCCAGCGTATGTAGCACCAGAGGTAATAAACAAGAAAGGTTATGATGGCGCAAAGGCGGATACATGGTCTTGTGGGGTTGTCCTCTTTGTTCTGCTGGCCGCCTTCCTGCCATTCCATGACACCAATCTCATGGAAATGTATAGGAAAATCAGCAGAGGAGACTTCAGGAGCCCTCAGTGGTTTCCCCCAGAGGTACGTAAGCTTCTTTCGAGGATTCTCGATCCTAATCCAAGCTCAAGAATAAGTGTTGACAAGATCATGGAGAATAGTTGGTTCAAGAAGGGGTTTAAACAAATCGAAGCATCTTTAGCCCCTCCGTGTGATCCAAACACCTCAATCCGTGATGTCCATGAGGCTTTTGCATCAACAAATCATTCAGCTGAAGAAAGTTCCAACAAGAATTCTAGCGGAGCAGGAACAAGCCCCATGAGGCCAACATGTTTCAATGCGTTCGACATCATATCTCTCTCGCCAGGTTTTGACCTATCCGGTTTGTTTGAGAATGATATGAATCACAGACCGCAGGAGCGATTCATGAGCACACAACCAGCCGCGACAATTGTTTCAAAATTTGAAGCCATAGCACAGACGGAGAGGTTCAAATGCCTGAAAAAAGACGGAACCCTTAAACTACAGGGTAGCAAGGAAGGAAGGAAAGGGCAGCTAGGCATCGATGCTGAGATTTTCGAGGTCACACCTTCATTTTATGTCGTGGAGATGAAGAAAACGGCTGGGGACACATTGGAATACATGGAGTTCTGTGACAATGGCTTGAAGCCCTCTCTTAAGGATATAGTATGGACTTGGCAAGGAACCGAGCAGCAACAGCAACCGCCGCTAGTAGTAGCACCTGAAGTCGTTTCTTAG

Functional Annotation

Gene Ontology

Molecular Function
Biological Process
Cellular Component

GO:0001101 GO:0003674 GO:0003824 GO:0004672 GO:0004674 GO:0005575 GO:0005622 GO:0005623 GO:0005737 GO:0005829 GO:0006464 GO:0006468 GO:0006793 GO:0006796 GO:0006807 GO:0007154 GO:0007165 GO:0008150 GO:0008152 GO:0009719 GO:0009725 GO:0009737 GO:0009987 GO:0010033 GO:0016301 GO:0016310 GO:0016740 GO:0016772 GO:0016773 GO:0018105 GO:0018107 GO:0018193 GO:0018209 GO:0018210 GO:0019538 GO:0023052 GO:0033993 GO:0035556 GO:0036211 GO:0042221 GO:0043170 GO:0043412 GO:0044237 GO:0044238 GO:0044260 GO:0044267 GO:0044424 GO:0044444 GO:0044464 GO:0050789 GO:0050794 GO:0050896 GO:0051716 GO:0065007 GO:0071704 GO:0097305 GO:0140096 GO:1901564 GO:1901700

KEGG Pathways

Metabolic & Signaling

ko04068 ko04113 ko04138 ko04140 ko04150 ko04151 ko04152 ko04211 ko04213 ko04371 ko04530 ko04710 ko04714 ko04910 ko04920 ko04921 ko04922 ko04931 ko04932 ko05410 ko05418 map04068 map04113 map04138 map04140 map04150 map04151 map04152 map04211 map04213 map04371 map04530 map04710 map04714 map04910 map04920 map04921 map04922 map04931 map04932 map05410 map05418

Pfam Domains

Protein Families

NAF Pkinase

Protein Analysis

464

Amino Acids

52.02

Weight (kDa)

8.9

Isoelectric Point (pI)

33.56

Instability Index

Protein Domains (Pfam)

Domain Name	Pfam ID	Position	E-value	Description
Pkinase	PF00069	13 - 267	1.7e-75	Protein kinase domain
PK_Tyr_Ser-Thr	PF07714	15 - 263	7.5e-40	Protein tyrosine and serine/threonine kinase
Kinase-like	PF14531	103 - 255	6.5e-10	Kinase-like
NAF	PF03822	320 - 377	1.8e-20	NAF domain

Hydrophobicity Profile (Kyte-Doolittle)

AI Structure Prediction Report

Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter

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Align Labels (Cladogram)

Image

Tree File

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Publication-ready

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Orthologous Genes (Group: OG0015822)

Species	Orthologous Gene IDs
arabidopsis_thaliana	AT5G45820
fragaria_vesca	FvH4_3g07630
malus_domestica	MD05G1298900.v1.1 MD10G1278400.v1.1
prunus_persica	Prupe.4G062900_v2.0.a1
rosa_chinensis	RchiOBHm_Chr5g0011061
rosa_laevigata	RLG00000031806
rosa_multiflora	Rmu_sc0003242.1_g000007
rosa_roxburghii	Rroxscaffold_1G00065350
rosa_rugosa	Rorug04G0454900
rosa_samantha	Rh5AG087000 Rh5BG081900 Rh5CG094700
rosa_wichuraiana	Rw0G000150 Rw0G017800

Restriction Enzyme Sites

1 / 10

Enzyme	Recognition Site	Cut Count	Positions (bp)
AccB1I	GGYRCC	1 cut(s)	207
AccII	CGCG	2 cut(s)	402, 1079
AciI	CCGC	9 cut(s)	285, 400, 581, 624, 933, 1046, 1077, 1358, 1361
AclWI	GGATC	2 cut(s)	740, 842
AcoI	YGGCCR	3 cut(s)	106, 240, 621
AcsI	RAATTY	2 cut(s)	925, 1094
AcuI	CTGAAG	3 cut(s)	119, 673, 927
AcvI	CACGTG	1 cut(s)	516
AdeI	CACNNNGTG	1 cut(s)	516
AfaI	GTAC	4 cut(s)	38, 275, 523, 720
AfiI	CCNNNNNNNGG	1 cut(s)	217
AflII	CTTAAG	2 cut(s)	320, 1310
AflIII	ACRYGT	2 cut(s)	515, 962
AgsI	TTSAA	7 cut(s)	298, 802, 970, 1092, 1100, 1126, 1300
AjnI	CCWGG	1 cut(s)	997
AloI	GAACNNNNNNTCC	2 cut(s)	86, 118
AluBI	AGCT	7 cut(s)	226, 292, 319, 727, 759, 905, 1189
AluI	AGCT	7 cut(s)	226, 292, 319, 727, 759, 905, 1189
Alw21I	GWGCWC	1 cut(s)	1067
Alw26I	GTCTC	1 cut(s)	678
AlwI	GGATC	2 cut(s)	740, 842
AlwNI	CAGNNNCTG	1 cut(s)	355
AoxI	GGCC	5 cut(s)	106, 240, 499, 621, 956
ApeKI	GCWGC	2 cut(s)	1186, 1345
ApoI	RAATTY	2 cut(s)	925, 1094
AspLEI	GCGC	3 cut(s)	198, 473, 575
AsuHPI	GGTGA	2 cut(s)	19, 389
BalI	TGGCCA	1 cut(s)	242
BanI	GGYRCC	1 cut(s)	207
BanII	GRGCYC	1 cut(s)	698
BarI	GAAGNNNNNNTAC	2 cut(s)	711, 743
BbrPI	CACGTG	1 cut(s)	516
Bbv12I	GWGCWC	1 cut(s)	1067
BbvI	GCAGC	2 cut(s)	1198, 1357
BccI	CCATC	2 cut(s)	491, 563
BceAI	ACGGC	1 cut(s)	1269
BciT130I	CCWGG	1 cut(s)	999
BciVI	GTATCC	1 cut(s)	577
BclI	TGATCA	1 cut(s)	166
BcoDI	GTCTC	1 cut(s)	678
BfaI	CTAG	4 cut(s)	486, 930, 1190, 1364
BfmI	CTRYAG	1 cut(s)	1157
BfrI	CTTAAG	2 cut(s)	320, 1310
BfuI	GTATCC	1 cut(s)	577
BisI	GCNGC	5 cut(s)	624, 1077, 1187, 1346, 1361
BlsI	GCNGC	5 cut(s)	625, 1078, 1188, 1347, 1362
Bme1390I	CCNGG	1 cut(s)	999
BmiI	GGNNCC	5 cut(s)	95, 209, 695, 1147, 1339
BmrFI	CCNGG	1 cut(s)	999
BmsI	GCATC	6 cut(s)	18, 183, 836, 896, 1189, 1203
BpuEI	CTTGAG	1 cut(s)	745
Bsa29I	ATCGAT	1 cut(s)	1197
BsaAI	YACGTR	3 cut(s)	277, 516, 722
BsaBI	GATNNNNATC	2 cut(s)	750, 1035
BsaJI	CCNNGG	2 cut(s)	75, 267
BsaWI	WCCGGW	1 cut(s)	1013
Bsc4I	CCNNNNNNNGG	1 cut(s)	217
Bse8I	GATNNNNATC	2 cut(s)	750, 1035
BseBI	CCWGG	1 cut(s)	999
BseCI	ATCGAT	1 cut(s)	1197
BseDI	CCNNGG	2 cut(s)	75, 267
BseJI	GATNNNNATC	2 cut(s)	750, 1035
BseLI	CCNNNNNNNGG	1 cut(s)	217
BseMII	CTCAG	2 cut(s)	713, 1194
BseRI	GAGGAG	2 cut(s)	494, 696
BseXI	GCAGC	2 cut(s)	1198, 1357
BseYI	CCCAGC	1 cut(s)	1256
BsgI	GTGCAG	1 cut(s)	167
Bsh1236I	CGCG	2 cut(s)	402, 1079
BshFI	GGCC	5 cut(s)	108, 242, 501, 623, 958
BshNI	GGYRCC	1 cut(s)	207
BshVI	ATCGAT	1 cut(s)	1197
BsiHKAI	GWGCWC	1 cut(s)	1067
BsiSI	CCGG	2 cut(s)	105, 1014
BslFI	GGGAC	4 cut(s)	60, 79, 504, 1274
BslI	CCNNNNNNNGG	1 cut(s)	217
BsmAI	GTCTC	1 cut(s)	678
BsmFI	GGGAC	4 cut(s)	60, 79, 504, 1274
BsnI	GGCC	5 cut(s)	108, 242, 501, 623, 958
Bsp1286I	GDGCHC	2 cut(s)	698, 1067
Bsp143I	GATC	5 cut(s)	166, 171, 745, 780, 847
Bsp19I	CCATGG	1 cut(s)	267
BspACI	CCGC	9 cut(s)	285, 400, 581, 624, 933, 1046, 1077, 1358, 1361
BspANI	GGCC	5 cut(s)	108, 242, 501, 623, 958
BspCNI	CTCAG	2 cut(s)	712, 1195
BspDI	ATCGAT	1 cut(s)	1197
BspFNI	CGCG	2 cut(s)	402, 1079
BspHI	TCATGA	1 cut(s)	1059
BspLI	GGNNCC	5 cut(s)	95, 209, 695, 1147, 1339
BspPI	GGATC	2 cut(s)	740, 842
BspT107I	GGYRCC	1 cut(s)	207
BspTI	CTTAAG	2 cut(s)	320, 1310
BssECI	CCNNGG	2 cut(s)	75, 267
BssMI	GATC	5 cut(s)	166, 171, 745, 780, 847
BssT1I	CCWWGG	2 cut(s)	75, 267
Bst2UI	CCWGG	1 cut(s)	999
Bst4CI	ACNGT	2 cut(s)	51, 383
BstAFI	CTTAAG	2 cut(s)	320, 1310
BstBAI	YACGTR	3 cut(s)	277, 516, 722
BstC8I	GCNNGC	3 cut(s)	244, 528, 621
BstDEI	CTNAG	3 cut(s)	699, 1203, 1389
BstDSI	CCRYGG	1 cut(s)	267
BstFNI	CGCG	2 cut(s)	402, 1079
BstHHI	GCGC	3 cut(s)	198, 473, 575
BstKTI	GATC	5 cut(s)	169, 174, 748, 783, 850
BstMAI	GTCTC	1 cut(s)	678
BstMBI	GATC	5 cut(s)	166, 171, 745, 780, 847
BstMWI	GCNNNNNNNGC	4 cut(s)	536, 833, 1351, 1360
BstNI	CCWGG	1 cut(s)	999
BstNSI	RCATGY	1 cut(s)	966
BstSCI	CCNGG	1 cut(s)	997
BstSFI	CTRYAG	1 cut(s)	1157
BstSNI	TACGTA	1 cut(s)	722
BstUI	CGCG	2 cut(s)	402, 1079
BstV1I	GCAGC	2 cut(s)	1198, 1357
BstXI	CCANNNNNNTGG	1 cut(s)	655
Bsu15I	ATCGAT	1 cut(s)	1197
BsuI	GTATCC	1 cut(s)	577
BsuRI	GGCC	5 cut(s)	108, 242, 501, 623, 958
BsuTUI	ATCGAT	1 cut(s)	1197
BtgI	CCRYGG	1 cut(s)	267
BtsIMutI	CAGTG	1 cut(s)	707
Cac8I	GCNNGC	3 cut(s)	244, 528, 621
CaiI	CAGNNNCTG	1 cut(s)	355
CciI	TCATGA	1 cut(s)	1059
CfoI	GCGC	3 cut(s)	198, 473, 575
ClaI	ATCGAT	1 cut(s)	1197
Csp6I	GTAC	4 cut(s)	37, 274, 522, 719
CviQI	GTAC	4 cut(s)	37, 274, 522, 719
DdeI	CTNAG	3 cut(s)	699, 1203, 1389
DpnI	GATC	5 cut(s)	168, 173, 747, 782, 849
DpnII	GATC	5 cut(s)	166, 171, 745, 780, 847
DraI	TTTAAA	1 cut(s)	814
DraIII	CACNNNGTG	1 cut(s)	516
EaeI	YGGCCR	3 cut(s)	106, 240, 621
EciI	GGCGGA	1 cut(s)	596
Eco105I	TACGTA	1 cut(s)	722
Eco130I	CCWWGG	2 cut(s)	75, 267
Eco24I	GRGCYC	1 cut(s)	698
Eco57I	CTGAAG	3 cut(s)	119, 673, 927
Eco72I	CACGTG	1 cut(s)	516
EcoRI	GAATTC	1 cut(s)	925
EcoRII	CCWGG	1 cut(s)	997
EcoT14I	CCWWGG	2 cut(s)	75, 267
EcoT38I	GRGCYC	1 cut(s)	698
ErhI	CCWWGG	2 cut(s)	75, 267
FalI	AAGNNNNNCTT	2 cut(s)	303, 335
FaqI	GGGAC	4 cut(s)	60, 79, 504, 1274
FauI	CCCGC	1 cut(s)	278
FbaI	TGATCA	1 cut(s)	166
Fnu4HI	GCNGC	5 cut(s)	624, 1077, 1187, 1346, 1361
FriOI	GRGCYC	1 cut(s)	698
Fsp4HI	GCNGC	5 cut(s)	624, 1077, 1187, 1346, 1361
FspBI	CTAG	4 cut(s)	486, 930, 1190, 1364
GlaI	GCGC	3 cut(s)	197, 472, 574
GluI	GCNGC	5 cut(s)	624, 1077, 1187, 1346, 1361
GsaI	CCCAGC	1 cut(s)	1260
HaeIII	GGCC	5 cut(s)	108, 242, 501, 623, 958
HapII	CCGG	2 cut(s)	105, 1014
HhaI	GCGC	3 cut(s)	198, 473, 575
Hin6I	GCGC	3 cut(s)	196, 471, 573
HinP1I	GCGC	3 cut(s)	196, 471, 573
HincII	GTYRAC	1 cut(s)	775
HindII	GTYRAC	1 cut(s)	775
HindIII	AAGCTT	2 cut(s)	317, 725
HinfI	GANTC	5 cut(s)	418, 482, 739, 1036, 1056
HpaII	CCGG	2 cut(s)	105, 1014
HphI	GGTGA	2 cut(s)	19, 389
Hpy166II	GTNNAC	3 cut(s)	82, 430, 775
Hpy188I	TCNGA	3 cut(s)	158, 171, 457
Hpy188III	TCNNGA	6 cut(s)	175, 691, 743, 762, 802, 1060
Hpy8I	GTNNAC	3 cut(s)	82, 430, 775
HpyAV	CCTTC	7 cut(s)	136, 145, 637, 799, 1166, 1170, 1233
HpyCH4III	ACNGT	2 cut(s)	51, 383
HpyCH4IV	ACGT	3 cut(s)	276, 515, 721
HpyCH4V	TGCA	5 cut(s)	31, 89, 119, 148, 887
HpyF10VI	GCNNNNNNNGC	4 cut(s)	536, 833, 1351, 1360
HpyF3I	CTNAG	3 cut(s)	699, 1203, 1389
HpySE526I	ACGT	3 cut(s)	276, 515, 721
HspAI	GCGC	3 cut(s)	196, 471, 573
Ksp22I	TGATCA	1 cut(s)	166
Kzo9I	GATC	5 cut(s)	166, 171, 745, 780, 847
LmnI	GCTCC	4 cut(s)	289, 693, 935, 1051
Lsp1109I	GCAGC	2 cut(s)	1198, 1357
LweI	GCATC	6 cut(s)	18, 183, 836, 896, 1189, 1203
MaeI	CTAG	4 cut(s)	486, 930, 1190, 1364
MaeII	ACGT	3 cut(s)	276, 515, 721
MaeIII	GTNAC	2 cut(s)	1216, 1286
MalI	GATC	5 cut(s)	168, 173, 747, 782, 849
MboI	GATC	5 cut(s)	166, 171, 745, 780, 847
MboII	GAAGA	3 cut(s)	338, 920, 1258
MfeI	CAATTG	1 cut(s)	1083
MhlI	GDGCHC	2 cut(s)	698, 1067
MlsI	TGGCCA	1 cut(s)	242
MluCI	AATT	4 cut(s)	120, 925, 1083, 1094
MluNI	TGGCCA	1 cut(s)	242
MlyI	GAGTC	1 cut(s)	491
MmeI	TCCRAC	2 cut(s)	136, 942
Mox20I	TGGCCA	1 cut(s)	242
MscI	TGGCCA	1 cut(s)	242
MseI	TTAA	6 cut(s)	123, 321, 467, 813, 1152, 1311
MslI	CAYNNNNRTG	3 cut(s)	26, 213, 659
Msp20I	TGGCCA	1 cut(s)	242
MspA1I	CMGCKG	1 cut(s)	905
MspCI	CTTAAG	2 cut(s)	320, 1310
MspI	CCGG	2 cut(s)	105, 1014
MspR9I	CCNGG	1 cut(s)	999
MssI	GTTTAAAC	1 cut(s)	814
MunI	CAATTG	1 cut(s)	1083
MvaI	CCWGG	1 cut(s)	999
MvnI	CGCG	2 cut(s)	402, 1079
MwoI	GCNNNNNNNGC	4 cut(s)	536, 833, 1351, 1360
NcoI	CCATGG	1 cut(s)	267
NdeII	GATC	5 cut(s)	166, 171, 745, 780, 847
NlaIV	GGNNCC	5 cut(s)	95, 209, 695, 1147, 1339
NmuCI	GTSAC	2 cut(s)	1216, 1286
NspI	RCATGY	1 cut(s)	966
PagI	TCATGA	1 cut(s)	1059
PciI	ACATGT	1 cut(s)	962
PfeI	GAWTC	4 cut(s)	418, 739, 1036, 1056
PkrI	GCNGC	5 cut(s)	625, 1078, 1188, 1347, 1362
PleI	GAGTC	1 cut(s)	490
PmaCI	CACGTG	1 cut(s)	516
PmeI	GTTTAAAC	1 cut(s)	814
PmlI	CACGTG	1 cut(s)	516
PpsI	GAGTC	1 cut(s)	490
Ppu21I	YACGTR	3 cut(s)	277, 516, 722
PscI	ACATGT	1 cut(s)	962
Psp6I	CCWGG	1 cut(s)	997
PspCI	CACGTG	1 cut(s)	516
PspFI	CCCAGC	1 cut(s)	1256
PspGI	CCWGG	1 cut(s)	997
PspN4I	GGNNCC	5 cut(s)	95, 209, 695, 1147, 1339
PstNI	CAGNNNCTG	1 cut(s)	355
PvuII	CAGCTG	1 cut(s)	905
RsaI	GTAC	4 cut(s)	38, 275, 523, 720
RsaNI	GTAC	4 cut(s)	37, 274, 522, 719
RseI	CAYNNNNRTG	3 cut(s)	26, 213, 659
SaqAI	TTAA	6 cut(s)	123, 321, 467, 813, 1152, 1311
SatI	GCNGC	5 cut(s)	624, 1077, 1187, 1346, 1361
Sau3AI	GATC	5 cut(s)	166, 171, 745, 780, 847
SchI	GAGTC	1 cut(s)	491
ScrFI	CCNGG	1 cut(s)	999
SduI	GDGCHC	2 cut(s)	698, 1067
SfaNI	GCATC	6 cut(s)	18, 183, 836, 896, 1189, 1203
SfcI	CTRYAG	1 cut(s)	1157
SmiMI	CAYNNNNRTG	3 cut(s)	26, 213, 659
SmlI	CTYRAG	3 cut(s)	320, 760, 1310
SmoI	CTYRAG	3 cut(s)	320, 760, 1310
SnaBI	TACGTA	1 cut(s)	722
Sse9I	AATT	4 cut(s)	120, 925, 1083, 1094
SsiI	CCGC	9 cut(s)	285, 400, 581, 624, 933, 1046, 1077, 1358, 1361
SspMI	CTAG	4 cut(s)	486, 930, 1190, 1364
StyD4I	CCNGG	1 cut(s)	997
StyI	CCWWGG	2 cut(s)	75, 267
TaaI	ACNGT	2 cut(s)	51, 383
TaiI	ACGT	3 cut(s)	279, 518, 724
TaqI	TCGA	9 cut(s)	132, 369, 385, 734, 744, 822, 978, 1197, 1212
TasI	AATT	4 cut(s)	120, 925, 1083, 1094
TauI	GCSGC	3 cut(s)	626, 1079, 1363
TfiI	GAWTC	4 cut(s)	418, 739, 1036, 1056
Tru1I	TTAA	6 cut(s)	123, 321, 467, 813, 1152, 1311
Tru9I	TTAA	6 cut(s)	123, 321, 467, 813, 1152, 1311
TscAI	CASTG	1 cut(s)	707
TseFI	GTSAC	2 cut(s)	1216, 1286
TseI	GCWGC	2 cut(s)	1186, 1345
Tsp45I	GTSAC	2 cut(s)	1216, 1286
TspDTI	ATGAA	4 cut(s)	1048, 1049, 1215, 1259
TspGWI	ACGGA	6 cut(s)	106, 178, 831, 854, 1130, 1158
TspRI	CASTG	1 cut(s)	707
Vha464I	CTTAAG	2 cut(s)	320, 1310
XapI	RAATTY	2 cut(s)	925, 1094
XceI	RCATGY	1 cut(s)	966
XcmI	CCANNNNNNNNNTGG	1 cut(s)	515
XspI	CTAG	4 cut(s)	486, 930, 1190, 1364

Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.