MD12G1103500.v1.1

caffeic acid

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
malus_domestica
Chr12
OG0011057
Physical Location & Seq
Forward (+)
16313422 .. 16319310
5889 bp
Loading structure...
UTR
Exon/CDS
Intron
MD12G1103500.v1.1.491

Sequence Viewer

Length: 1107 bp
ATGGAGGGGAATAATCAAGTGAGTAACGTGACCGCAGGGCCAAGCAGCAGCAACAACGAAGCAAGACTGGCTATACTGGAGCTGGCCAACATGATTAGCGTCCCCATGTCTCTAAACGCCGTTGTTCGACTTAACGTCCCCGACGCCATCTGGCAGGGCGGTTGCAACACTCCTCTCTCCGCCTCTGACGTGCTCGCACGCGTCATCCCTAATGGCGGGGGCGACGCCGAGAACCTCCAGCGCATCCTCCGCATGCTCACCAGCTACGGTGTGTTTGAGGAGCATCTGAGCAACCTGGACGACGGCTCCGACGACAGAAAGTTCTCCCTCACTCCAATTGGTCAAACCCTCGTCACGGACCAAAACGGCTTGTCGTACGGCCCTTACGTCCTCCAACACCACCAGGATGTGCTTATGGGAGCGTGGCCAATGGTTCACGAGGCGGTGGTGGACTCCACGGTGGAGCCATTTGTGAAGGCGAACGGTGAGCTGGCTTACGAGTACTACGGGAAGAAGCCGGAGATGAACGGCCTAATGCAAAAGGCGATGTCGGGTGTGTCAGTGCCGTTCATGAAGGCGATTTTGGATGGCTACGACGGATTTGAAGGGGTGGAGAGGCTGGTGGATGTGGGAGGGAGTGCAGGGGATTGCCTGCGGATGATCCTACAGAAGCATCCTAATGTGAGGGAAGGAATTAATTTCGACTTGCCTGAGGTCGTTGCCAAGGCACCAACCATAGCTGGAGTGAGTCACGTTGGTGGTGACATGTTCAAGTCAATTCCTAGGGGTGACGCTATTTTTTTGAAGTGGATTTTATCAACGTGGACGGATAGCGAATGCAAGGTGATACTGGAGAATTGTTACAAAGCACTTCCGGAAGGAGGGAAGCTTATAGCTTGTGAGCCGGTATTGCCAAAGAAATCAGACGAGAGTCATAGGACCCGTGCGCTTCTAGAAAACGACATATTTGTGATGACCATCTACCGGGCCAAGGGCAAGAATAGGAGCGAAGATGAACTCCGGCAGCTCGGTCTCTCCGCTGGTTTCTCCCATTTCAAACCATTCTACATCGATTATTTCTACACCGTCATAGAATTCCAAAAGTGA
Functional Annotation
Gene Ontology
Molecular Function
Biological Process
Cellular Component
No ontology terms assigned.
KEGG Pathways
Metabolic & Signaling
No pathways identified.
Pfam Domains
Protein Families
Dimerisation Methyltransf_2

Protein Analysis

369

Amino Acids

40.47

Weight (kDa)

5.2

Isoelectric Point (pI)

31.78

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
Dimerisation PF08100 26 - 120 3.4e-15 O-methyltransferase dimerisation domain
Methyltransf_2 PF00891 142 - 350 2.8e-45 O-methyltransferase domain
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
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Publication-ready
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Orthologous Genes (Group: OG0011057)

Species Orthologous Gene IDs
arabidopsis_thaliana AT3G53140
fragaria_vesca FvH4_6g17130 FvH4_6g17130 FvH4_6g17130
malus_domestica MD12G1103500.v1.1 MD14G1097900.v1.1
prunus_persica Prupe.7G123600_v2.0.a1
pyrus_communis pycom12g10200
rosa_chinensis RchiOBHm_Chr3g0471211
rosa_laevigata RLG00000024197
rosa_multiflora Rmu_co8165034.1_g000001 Rmu_sc0010073.1_g000018 Rmu_sc0031310.1_g000002
rosa_roxburghii Rroxscaffold_6G00410220
rosa_rugosa Rorug03G0116200
rosa_samantha Rh3AG165100 Rh3BG190700 Rh3CG181000 Rh3DG185100
rosa_wichuraiana Rw3G015570

Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AccB1I GGYRCC 1 cut(s) 727
AccII CGCG 1 cut(s) 201
AccIII TCCGGA 1 cut(s) 874
AciI CCGC 8 cut(s) 33, 159, 180, 216, 250, 443, 655, 1038
AclWI GGATC 1 cut(s) 655
AcoI YGGCCR 2 cut(s) 84, 425
AcsI RAATTY 1 cut(s) 1094
AcyI GRCGYC 2 cut(s) 144, 225
AfaI GTAC 2 cut(s) 377, 503
AfiI CCNNNNNNNGG 5 cut(s) 215, 355, 881, 984, 991
AflIII ACRYGT 2 cut(s) 199, 765
AgsI TTSAA 4 cut(s) 605, 772, 805, 1057
AhdI GACNNNNNGTC 1 cut(s) 134
AjiI CACGTC 1 cut(s) 190
AjnI CCWGG 2 cut(s) 294, 402
AjuI GAANNNNNNNTTGG 2 cut(s) 566, 598
AleI CACNNNNGTG 1 cut(s) 756
AluBI AGCT 7 cut(s) 82, 264, 490, 740, 889, 896, 1027
AluI AGCT 7 cut(s) 82, 264, 490, 740, 889, 896, 1027
Alw21I GWGCWC 1 cut(s) 195
Alw26I GTCTC 2 cut(s) 114, 1037
AlwI GGATC 1 cut(s) 655
Aor13HI TCCGGA 1 cut(s) 874
AoxI GGCC 6 cut(s) 38, 84, 379, 425, 529, 987
ApeKI GCWGC 3 cut(s) 45, 48, 1024
ApoI RAATTY 1 cut(s) 1094
AseI ATTAAT 1 cut(s) 696
AspA2I CCTAGG 1 cut(s) 782
AspLEI GCGC 2 cut(s) 243, 949
AspS9I GGNCC 5 cut(s) 38, 358, 380, 939, 987
AsuC2I CCSGG 1 cut(s) 986
AsuHPI GGTGA 5 cut(s) 250, 497, 773, 800, 856
AvaII GGWCC 2 cut(s) 358, 939
AvrII CCTAGG 1 cut(s) 782
AxyI CCTNAGG 1 cut(s) 711
BalI TGGCCA 2 cut(s) 86, 427
BanI GGYRCC 1 cut(s) 727
BauI CACGAG 1 cut(s) 437
Bbv12I GWGCWC 1 cut(s) 195
BbvI GCAGC 3 cut(s) 57, 60, 1036
BccI CCATC 3 cut(s) 155, 581, 986
BceAI ACGGC 6 cut(s) 104, 319, 382, 394, 544, 550
BciT130I CCWGG 2 cut(s) 296, 404
BcnI CCSGG 1 cut(s) 986
BcoDI GTCTC 2 cut(s) 114, 1037
BfaI CTAG 2 cut(s) 783, 953
BfmI CTRYAG 1 cut(s) 665
BisI GCNGC 3 cut(s) 46, 49, 1025
BlnI CCTAGG 1 cut(s) 782
BlsI GCNGC 3 cut(s) 47, 50, 1026
BmcAI AGTACT 1 cut(s) 503
Bme1390I CCNGG 3 cut(s) 296, 404, 986
Bme18I GGWCC 2 cut(s) 358, 939
BmeRI GACNNNNNGTC 1 cut(s) 134
BmgBI CACGTC 1 cut(s) 190
BmgT120I GGNCC 5 cut(s) 38, 358, 380, 939, 987
BmiI GGNNCC 4 cut(s) 307, 465, 729, 941
BmrFI CCNGG 3 cut(s) 296, 404, 986
BmsI GCATC 3 cut(s) 252, 292, 682
BoxI GACNNNNGTC 1 cut(s) 930
BpmI CTGGAG 4 cut(s) 98, 221, 762, 872
BpuMI CCSGG 1 cut(s) 986
Bsa29I ATCGAT 1 cut(s) 1071
BsaBI GATNNNNATC 1 cut(s) 977
BsaHI GRCGYC 2 cut(s) 144, 225
BsaI GGTCTC 1 cut(s) 1037
BsaJI CCNNGG 4 cut(s) 456, 723, 782, 990
BsaWI WCCGGW 1 cut(s) 874
BsaXI ACNNNNNCTCC 2 cut(s) 290, 320
Bsc4I CCNNNNNNNGG 5 cut(s) 215, 355, 881, 984, 991
Bse118I RCCGGY 1 cut(s) 904
Bse1I ACTGG 3 cut(s) 72, 81, 855
Bse21I CCTNAGG 1 cut(s) 711
Bse8I GATNNNNATC 1 cut(s) 977
BseAI TCCGGA 1 cut(s) 874
BseBI CCWGG 2 cut(s) 296, 404
BseCI ATCGAT 1 cut(s) 1071
BseDI CCNNGG 4 cut(s) 456, 723, 782, 990
BseGI GGATG 7 cut(s) 204, 243, 412, 592, 631, 663, 673
BseJI GATNNNNATC 1 cut(s) 977
BseLI CCNNNNNNNGG 5 cut(s) 215, 355, 881, 984, 991
BseMII CTCAG 2 cut(s) 278, 702
BseNI ACTGG 3 cut(s) 72, 81, 855
BseRI GAGGAG 2 cut(s) 162, 293
BseXI GCAGC 3 cut(s) 57, 60, 1036
BsgI GTGCAG 1 cut(s) 660
Bsh1236I CGCG 1 cut(s) 201
BshFI GGCC 6 cut(s) 40, 86, 381, 427, 531, 989
BshNI GGYRCC 1 cut(s) 727
BshVI ATCGAT 1 cut(s) 1071
BsiHKAI GWGCWC 1 cut(s) 195
BsiSI CCGG 5 cut(s) 518, 875, 905, 985, 1021
BsiWI CGTACG 1 cut(s) 375
BslFI GGGAC 2 cut(s) 86, 122
BslI CCNNNNNNNGG 5 cut(s) 215, 355, 881, 984, 991
BsmAI GTCTC 2 cut(s) 114, 1037
BsmFI GGGAC 2 cut(s) 86, 122
BsmI GAATGC 1 cut(s) 842
BsnI GGCC 6 cut(s) 40, 86, 381, 427, 531, 989
Bso31I GGTCTC 1 cut(s) 1037
Bsp1286I GDGCHC 1 cut(s) 195
Bsp13I TCCGGA 1 cut(s) 874
Bsp143I GATC 1 cut(s) 660
BspACI CCGC 8 cut(s) 33, 159, 180, 216, 250, 443, 655, 1038
BspANI GGCC 6 cut(s) 40, 86, 381, 427, 531, 989
BspCNI CTCAG 2 cut(s) 279, 703
BspDI ATCGAT 1 cut(s) 1071
BspEI TCCGGA 1 cut(s) 874
BspFNI CGCG 1 cut(s) 201
BspHI TCATGA 1 cut(s) 570
BspLI GGNNCC 4 cut(s) 307, 465, 729, 941
BspPI GGATC 1 cut(s) 655
BspT107I GGYRCC 1 cut(s) 727
BspTNI GGTCTC 1 cut(s) 1037
BsrFI RCCGGY 1 cut(s) 904
BsrI ACTGG 3 cut(s) 72, 81, 855
BssAI RCCGGY 1 cut(s) 904
BssECI CCNNGG 4 cut(s) 456, 723, 782, 990
BssMI GATC 1 cut(s) 660
BssNI GRCGYC 2 cut(s) 144, 225
BssSI CACGAG 1 cut(s) 437
BssT1I CCWWGG 3 cut(s) 723, 782, 990
Bst2BI CACGAG 1 cut(s) 437
Bst2UI CCWGG 2 cut(s) 296, 404
Bst4CI ACNGT 4 cut(s) 269, 460, 485, 1087
BstACI GRCGYC 2 cut(s) 144, 225
BstC8I GCNNGC 6 cut(s) 84, 195, 199, 254, 492, 653
BstDEI CTNAG 2 cut(s) 287, 711
BstDSI CCRYGG 1 cut(s) 456
BstF5I GGATG 7 cut(s) 204, 243, 412, 592, 631, 663, 673
BstFNI CGCG 1 cut(s) 201
BstHHI GCGC 2 cut(s) 243, 949
BstKTI GATC 1 cut(s) 663
BstMAI GTCTC 2 cut(s) 114, 1037
BstMBI GATC 1 cut(s) 660
BstMWI GCNNNNNNNGC 3 cut(s) 68, 249, 910
BstNI CCWGG 2 cut(s) 296, 404
BstNSI RCATGY 2 cut(s) 256, 769
BstPAI GACNNNNGTC 1 cut(s) 930
BstSCI CCNGG 3 cut(s) 294, 402, 984
BstSFI CTRYAG 1 cut(s) 665
BstUI CGCG 1 cut(s) 201
BstV1I GCAGC 3 cut(s) 57, 60, 1036
Bsu15I ATCGAT 1 cut(s) 1071
Bsu36I CCTNAGG 1 cut(s) 711
BsuRI GGCC 6 cut(s) 40, 86, 381, 427, 531, 989
BsuTUI ATCGAT 1 cut(s) 1071
BtgI CCRYGG 1 cut(s) 456
BtgZI GCGATG 1 cut(s) 560
BtrI CACGTC 1 cut(s) 190
BtsCI GGATG 7 cut(s) 204, 243, 412, 592, 631, 663, 673
BtsIMutI CAGTG 1 cut(s) 567
Cac8I GCNNGC 6 cut(s) 84, 195, 199, 254, 492, 653
CciI TCATGA 1 cut(s) 570
CfoI GCGC 2 cut(s) 243, 949
Cfr10I RCCGGY 1 cut(s) 904
Cfr13I GGNCC 5 cut(s) 38, 358, 380, 939, 987
ClaI ATCGAT 1 cut(s) 1071
CseI GACGC 5 cut(s) 88, 152, 190, 233, 800
Csp6I GTAC 2 cut(s) 376, 502
CviAII CATG 5 cut(s) 91, 106, 253, 571, 766
CviQI GTAC 2 cut(s) 376, 502
DdeI CTNAG 2 cut(s) 287, 711
DpnI GATC 1 cut(s) 662
DpnII GATC 1 cut(s) 660
DriI GACNNNNNGTC 1 cut(s) 134
EaeI YGGCCR 2 cut(s) 84, 425
Eam1105I GACNNNNNGTC 1 cut(s) 134
EciI GGCGGA 1 cut(s) 169
Eco130I CCWWGG 3 cut(s) 723, 782, 990
Eco31I GGTCTC 1 cut(s) 1037
Eco47I GGWCC 2 cut(s) 358, 939
Eco81I CCTNAGG 1 cut(s) 711
EcoO109I RGGNCCY 1 cut(s) 939
EcoRI GAATTC 1 cut(s) 1094
EcoRII CCWGG 2 cut(s) 294, 402
EcoT14I CCWWGG 3 cut(s) 723, 782, 990
ErhI CCWWGG 3 cut(s) 723, 782, 990
FaeI CATG 5 cut(s) 94, 109, 256, 574, 769
FaqI GGGAC 2 cut(s) 86, 122
FatI CATG 5 cut(s) 90, 105, 252, 570, 765
FauI CCCGC 1 cut(s) 209
Fnu4HI GCNGC 3 cut(s) 46, 49, 1025
FokI GGATG 7 cut(s) 191, 230, 419, 599, 638, 660, 670
Fsp4HI GCNGC 3 cut(s) 46, 49, 1025
FspBI CTAG 2 cut(s) 783, 953
GlaI GCGC 2 cut(s) 242, 948
GluI GCNGC 3 cut(s) 46, 49, 1025
GsuI CTGGAG 4 cut(s) 98, 221, 762, 872
HaeIII GGCC 6 cut(s) 40, 86, 381, 427, 531, 989
HapII CCGG 5 cut(s) 518, 875, 905, 985, 1021
HgaI GACGC 5 cut(s) 88, 152, 190, 233, 800
HhaI GCGC 2 cut(s) 243, 949
Hin1I GRCGYC 2 cut(s) 144, 225
Hin1II CATG 5 cut(s) 94, 109, 256, 574, 769
Hin6I GCGC 2 cut(s) 241, 947
HinP1I GCGC 2 cut(s) 241, 947
HindIII AAGCTT 1 cut(s) 887
HinfI GANTC 3 cut(s) 452, 748, 931
HpaII CCGG 5 cut(s) 518, 875, 905, 985, 1021
HphI GGTGA 5 cut(s) 250, 497, 773, 800, 856
Hpy166II GTNNAC 3 cut(s) 436, 451, 825
Hpy188I TCNGA 4 cut(s) 187, 288, 310, 925
Hpy188III TCNNGA 4 cut(s) 437, 571, 875, 953
Hpy8I GTNNAC 3 cut(s) 436, 451, 825
Hpy99I CGWCG 5 cut(s) 146, 227, 305, 314, 599
HpyAV CCTTC 5 cut(s) 469, 568, 599, 683, 872
HpyCH4III ACNGT 4 cut(s) 269, 460, 485, 1087
HpyCH4IV ACGT 6 cut(s) 27, 135, 189, 387, 753, 821
HpyCH4V TGCA 4 cut(s) 165, 538, 641, 840
HpyF10VI GCNNNNNNNGC 3 cut(s) 68, 249, 910
HpyF3I CTNAG 2 cut(s) 287, 711
HpySE526I ACGT 6 cut(s) 27, 135, 189, 387, 753, 821
Hsp92I GRCGYC 2 cut(s) 144, 225
Hsp92II CATG 5 cut(s) 94, 109, 256, 574, 769
HspAI GCGC 2 cut(s) 241, 947
Kpn2I TCCGGA 1 cut(s) 874
Kzo9I GATC 1 cut(s) 660
LmnI GCTCC 6 cut(s) 79, 280, 311, 419, 463, 1005
Lsp1109I GCAGC 3 cut(s) 57, 60, 1036
LweI GCATC 3 cut(s) 252, 292, 682
MaeI CTAG 2 cut(s) 783, 953
MaeII ACGT 6 cut(s) 27, 135, 189, 387, 753, 821
MaeIII GTNAC 7 cut(s) 23, 28, 352, 749, 761, 788, 860
MalI GATC 1 cut(s) 662
MboI GATC 1 cut(s) 660
MboII GAAGA 2 cut(s) 523, 1022
MfeI CAATTG 1 cut(s) 336
MhlI GDGCHC 1 cut(s) 195
MlsI TGGCCA 2 cut(s) 86, 427
MluCI AATT 6 cut(s) 336, 693, 697, 777, 856, 1094
MluI ACGCGT 1 cut(s) 199
MluNI TGGCCA 2 cut(s) 86, 427
MlyI GAGTC 3 cut(s) 446, 757, 940
MmeI TCCRAC 2 cut(s) 333, 418
Mox20I TGGCCA 2 cut(s) 86, 427
MroI TCCGGA 1 cut(s) 874
MscI TGGCCA 2 cut(s) 86, 427
MseI TTAA 2 cut(s) 132, 696
MslI CAYNNNNRTG 4 cut(s) 405, 678, 756, 968
Msp20I TGGCCA 2 cut(s) 86, 427
MspA1I CMGCKG 1 cut(s) 1040
MspI CCGG 5 cut(s) 518, 875, 905, 985, 1021
MspR9I CCNGG 3 cut(s) 296, 404, 986
MunI CAATTG 1 cut(s) 336
Mva1269I GAATGC 1 cut(s) 842
MvaI CCWGG 2 cut(s) 296, 404
MvnI CGCG 1 cut(s) 201
MwoI GCNNNNNNNGC 3 cut(s) 68, 249, 910
NciI CCSGG 1 cut(s) 986
NdeII GATC 1 cut(s) 660
NlaIII CATG 5 cut(s) 94, 109, 256, 574, 769
NlaIV GGNNCC 4 cut(s) 307, 465, 729, 941
NmeAIII GCCGAG 1 cut(s) 253
NmuCI GTSAC 5 cut(s) 28, 352, 749, 761, 788
NspI RCATGY 2 cut(s) 256, 769
OliI CACNNNNGTG 1 cut(s) 756
PaeI GCATGC 1 cut(s) 256
PagI TCATGA 1 cut(s) 570
PciI ACATGT 1 cut(s) 765
PcsI WCGNNNNNNNCGW 3 cut(s) 306, 309, 384
PctI GAATGC 1 cut(s) 842
Pfl23II CGTACG 1 cut(s) 375
PkrI GCNGC 3 cut(s) 47, 50, 1026
PleI GAGTC 3 cut(s) 446, 756, 939
PpsI GAGTC 3 cut(s) 446, 756, 939
PpuMI RGGWCCY 1 cut(s) 939
PscI ACATGT 1 cut(s) 765
PshAI GACNNNNGTC 1 cut(s) 930
PshBI ATTAAT 1 cut(s) 696
Psp5II RGGWCCY 1 cut(s) 939
Psp6I CCWGG 2 cut(s) 294, 402
PspGI CCWGG 2 cut(s) 294, 402
PspLI CGTACG 1 cut(s) 375
PspN4I GGNNCC 4 cut(s) 307, 465, 729, 941
PspPI GGNCC 5 cut(s) 38, 358, 380, 939, 987
PspPPI RGGWCCY 1 cut(s) 939
RsaI GTAC 2 cut(s) 377, 503
RsaNI GTAC 2 cut(s) 376, 502
RseI CAYNNNNRTG 4 cut(s) 405, 678, 756, 968
SaqAI TTAA 2 cut(s) 132, 696
SatI GCNGC 3 cut(s) 46, 49, 1025
Sau3AI GATC 1 cut(s) 660
Sau96I GGNCC 5 cut(s) 38, 358, 380, 939, 987
ScaI AGTACT 1 cut(s) 503
SchI GAGTC 3 cut(s) 446, 757, 940
ScrFI CCNGG 3 cut(s) 296, 404, 986
SduI GDGCHC 1 cut(s) 195
SfaNI GCATC 3 cut(s) 252, 292, 682
SfcI CTRYAG 1 cut(s) 665
SinI GGWCC 2 cut(s) 358, 939
SmiMI CAYNNNNRTG 4 cut(s) 405, 678, 756, 968
SphI GCATGC 1 cut(s) 256
Sse9I AATT 6 cut(s) 336, 693, 697, 777, 856, 1094
SsiI CCGC 8 cut(s) 33, 159, 180, 216, 250, 443, 655, 1038
SspMI CTAG 2 cut(s) 783, 953
StyD4I CCNGG 3 cut(s) 294, 402, 984
StyI CCWWGG 3 cut(s) 723, 782, 990
TaaI ACNGT 4 cut(s) 269, 460, 485, 1087
TaiI ACGT 6 cut(s) 30, 138, 192, 390, 756, 824
TaqI TCGA 3 cut(s) 127, 702, 1071
TaqII GACCGA 1 cut(s) 1019
TasI AATT 6 cut(s) 336, 693, 697, 777, 856, 1094
TatI WGTACW 1 cut(s) 501
Tru1I TTAA 2 cut(s) 132, 696
Tru9I TTAA 2 cut(s) 132, 696
TscAI CASTG 1 cut(s) 567
TseFI GTSAC 5 cut(s) 28, 352, 749, 761, 788
TseI GCWGC 3 cut(s) 45, 48, 1024
Tsp45I GTSAC 5 cut(s) 28, 352, 749, 761, 788
TspDTI ATGAA 4 cut(s) 539, 559, 587, 1029
TspGWI ACGGA 3 cut(s) 371, 612, 842
TspRI CASTG 1 cut(s) 567
VpaK11BI GGWCC 2 cut(s) 358, 939
VspI ATTAAT 1 cut(s) 696
XapI RAATTY 1 cut(s) 1094
XbaI TCTAGA 1 cut(s) 952
XceI RCATGY 2 cut(s) 256, 769
XmaJI CCTAGG 1 cut(s) 782
XspI CTAG 2 cut(s) 783, 953
ZrmI AGTACT 1 cut(s) 503
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.