Basic Information

Type: gene

Biological Identity

Species

malus_domestica

Chromosome

Chr15

Orthogroup ID

OG0005879

Physical Location & Seq

Genomic Coordinates Reverse (-)

7919669 .. 7923893

Gene Structure 4225 bp

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UTR

Exon/CDS

Intron

Transcript / Protein ID

MD15G1112600.v1.1.491

Sequence Viewer

CDS Protein Promoter (2k)

Length: 1266 bp

ATGCAGATAGTTCTATCAGGAGAACCAGTGCATAGTCTTCCCAAGATAAATTCACTTATAGCTGCCAATGATAATGATAATAATGTTGATGGTGTCCAGCAACATCCGTTGAGGCTATATTTGGATTATGTTGGCTATCTCTACCAGAGGATGGATCCCCTTCCGGAGCAAGAACGGCTTGAGATTGGTTACAGGGATTACTTGCCGTCACCCTTACAGCCTCTCATGGATAATCTAGAAGCTCAAACCTATGAGACATTTGAGAAGGACACAATGAAATATATTCAGTACCAAAGAGCAATTTGTAAAGCTTTACAGGACAGGGTTCCAGATGACAAGGCATCTTCTGTAACTACCGTATTGATGGTTTTAGGAGCAGGACGTGGACCTCTTGTAAGGGCATCATTGCAGGCAGCTGAAGAAACTGGGCGCAAGCTTAAAGTGTACGCTGTCGAAAAAAATCCAAATGCAGTTGTTACACTTCATAGCTTGGTTAAACTGGAGGTGTGGGAAAACATTGTTTCCATAATTTCATGTGATATGCGTTACTGGGATGCTCCAGAGAAAGCTGACATTTTGGTTAGTGAATTGTTGGGTTCTTTTGGTGATAACGAGCTGTCTCCTGAGTGCCTTGATGGAGCTCAGAGACTTTTGAAGGATGATGGAATCTTGATACCTTCATCGTACACGGGTTTTATCCAACCGGTGACTGCTTCAAAGCTTTACAATGATGTATGCCCGTGTCTTTTCGCGCACAAAGATATTGCACACTTTGAAACTGCTTATGTTGTTAAATTGCACAACATTGGAAGACTTGCTCTTCCTCAACCTGTTTTCACGTTTGATCACTCAAAACGCTCTACTGACAAAAGCAATAACCGGTACACGAAGTTGCAGTTTGGAATAACAAGTGATACTGGCTCAGCCATGATTCACGGATTTGCTGGCTATTTTGATGCAACATTATACAAAGAAGTTCATCTTGGCATTGAACCATCAACATCAACACCAAACATGTTTAGCTGGTTCCCGATATTTTTCCCACTAAGGACACCTATTACGCTTAGTCCTGGCGCTTCTCTTGAACTACATTTCTGGCGGTGTTGTCATCCTACCAAGGTTTGGTACGAATGGTGCGTGGCTTCGCCCTCCAGTTCGCCAGTTCACCAGTTCACAACAGCAACGGACGTTCATACTGGGTTGGGCTCCAGTAGCCCCGCGATTTTGTTCTACAACAAGTTTCGACATCTATGCCCATTTTCATAG

Functional Annotation

Gene Ontology

Molecular Function
Biological Process
Cellular Component

GO:0003674 GO:0003824 GO:0005575 GO:0005622 GO:0005623 GO:0005634 GO:0005737 GO:0005829 GO:0006325 GO:0006355 GO:0006464 GO:0006479 GO:0006807 GO:0006996 GO:0008150 GO:0008152 GO:0008168 GO:0008170 GO:0008213 GO:0008276 GO:0008469 GO:0008757 GO:0009889 GO:0009909 GO:0009987 GO:0010219 GO:0010220 GO:0010468 GO:0010556 GO:0016043 GO:0016273 GO:0016274 GO:0016569 GO:0016570 GO:0016571 GO:0016740 GO:0016741 GO:0018193 GO:0018195 GO:0018216 GO:0019219 GO:0019222 GO:0019538 GO:0019918 GO:0031323 GO:0031326 GO:0032259 GO:0034969 GO:0035246 GO:0035247 GO:0036211 GO:0042054 GO:0043170 GO:0043226 GO:0043227 GO:0043229 GO:0043231 GO:0043412 GO:0043414 GO:0043985 GO:0044237 GO:0044238 GO:0044260 GO:0044267 GO:0044424 GO:0044444 GO:0044464 GO:0048518 GO:0048580 GO:0048583 GO:0048584 GO:0048831 GO:0050789 GO:0050793 GO:0050794 GO:0051171 GO:0051239 GO:0051252 GO:0051276 GO:0060255 GO:0065007 GO:0071704 GO:0071840 GO:0080090 GO:0080134 GO:0140096 GO:1901564 GO:1903506 GO:2000026 GO:2000112 GO:2000241 GO:2001141

KEGG Pathways

Metabolic & Signaling

ko03013 ko04011 ko04111 map03013 map04011 map04111

Pfam Domains

Protein Families

PRMT5 PRMT5_C PRMT5_TIM

Protein Analysis

422

Amino Acids

47.34

Weight (kDa)

5.87

Isoelectric Point (pI)

41.33

Instability Index

Protein Domains (Pfam)

Domain Name	Pfam ID	Position	E-value	Description
PRMT5	PF05185	57 - 225	1.1e-70	PRMT5 arginine-N-methyltransferase
TRM5-TYW2_MTfase	PF02475	120 - 223	2e-06	TRM5/TYW2 methyltransferase domain
PRMT5_C	PF17286	228 - 388	9.1e-55	PRMT5 oligomerisation domain

Hydrophobicity Profile (Kyte-Doolittle)

AI Structure Prediction Report

Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter

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Align Labels (Cladogram)

Image

Tree File

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Publication-ready

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Orthologous Genes (Group: OG0005879)

Species	Orthologous Gene IDs
arabidopsis_thaliana	AT4G31120 AT4G31120
fragaria_vesca	FvH4_2g30610 FvH4_2g30610 FvH4_2g30610 FvH4_2g30610 FvH4_2g30610
malus_domestica	MD08G1132700.v1.1 MD15G1111800.v1.1 MD15G1112100.v1.1 MD15G1112600.v1.1 MD15G1112700.v1.1
prunus_persica	Prupe.1G463300_v2.0.a1 Prupe.1G463300_v2.0.a1
pyrus_communis	pycom08g11190 pycom15g10130
rosa_chinensis	RchiOBHm_Chr6g0312391
rosa_laevigata	RLG00000010331
rosa_multiflora	Rmu_sc0028838.1_g000001 Rmu_sc0031621.1_g000001 Rmu_ssc0000424.1_g000022
rosa_roxburghii	Rroxscaffold_7G00156840
rosa_rugosa	Rorug06G0395500
rosa_samantha	Rh6AG512700 Rh6BG523600 Rh6CG529000 Rh6DG514900
rosa_wichuraiana	Rw6G044560

Restriction Enzyme Sites

1 / 10

Enzyme	Recognition Site	Cut Count	Positions (bp)
AccB7I	CCANNNNNTGG	2 cut(s)	151, 1122
AccII	CGCG	2 cut(s)	752, 1220
AccIII	TCCGGA	1 cut(s)	163
AciI	CCGC	2 cut(s)	1099, 1218
AclWI	GGATC	2 cut(s)	149, 162
AcsI	RAATTY	1 cut(s)	49
AcuI	CTGAAG	1 cut(s)	438
AfaI	GTAC	5 cut(s)	290, 446, 686, 884, 1127
AfiI	CCNNNNNNNGG	2 cut(s)	151, 1122
AflIII	ACRYGT	1 cut(s)	1014
AgeI	ACCGGT	2 cut(s)	703, 879
AgsI	TTSAA	5 cut(s)	655, 717, 776, 992, 1085
AjiI	CACGTC	1 cut(s)	383
AjnI	CCWGG	1 cut(s)	1069
AjuI	GAANNNNNNNTTGG	2 cut(s)	966, 998
Alw21I	GWGCWC	1 cut(s)	643
Alw26I	GTCTC	3 cut(s)	248, 624, 640
AlwI	GGATC	2 cut(s)	149, 162
Aor13HI	TCCGGA	1 cut(s)	163
ApeKI	GCWGC	2 cut(s)	62, 413
ApoI	RAATTY	1 cut(s)	49
AsiGI	ACCGGT	2 cut(s)	703, 879
AspLEI	GCGC	3 cut(s)	432, 754, 1076
AspS9I	GGNCC	1 cut(s)	386
AsuHPI	GGTGA	4 cut(s)	201, 617, 718, 1157
AvaII	GGWCC	1 cut(s)	386
BamHI	GGATCC	1 cut(s)	154
BanII	GRGCYC	2 cut(s)	643, 1208
BbsI	GAAGAC	2 cut(s)	29, 817
Bbv12I	GWGCWC	1 cut(s)	643
BbvI	GCAGC	2 cut(s)	49, 425
BccI	CCATC	6 cut(s)	83, 145, 358, 629, 656, 1003
BceAI	ACGGC	2 cut(s)	190, 191
BcgI	CGANNNNNNTGC	1 cut(s)	1233
BciT130I	CCWGG	1 cut(s)	1071
BclI	TGATCA	1 cut(s)	844
BcoDI	GTCTC	3 cut(s)	248, 624, 640
BfaI	CTAG	1 cut(s)	236
BfoI	RGCGCY	1 cut(s)	1077
BisI	GCNGC	2 cut(s)	63, 414
BlpI	GCTNAGC	1 cut(s)	922
BlsI	GCNGC	2 cut(s)	64, 415
Bme1390I	CCNGG	1 cut(s)	1071
Bme18I	GGWCC	1 cut(s)	386
BmgBI	CACGTC	1 cut(s)	383
BmgT120I	GGNCC	1 cut(s)	386
BmiI	GGNNCC	4 cut(s)	156, 327, 1028, 1207
BmrFI	CCNGG	1 cut(s)	1071
BmrI	ACTGGG	3 cut(s)	435, 559, 1206
BmsI	GCATC	4 cut(s)	350, 410, 544, 946
BmuI	ACTGGG	3 cut(s)	435, 559, 1206
BpiI	GAAGAC	2 cut(s)	29, 817
BpmI	CTGGAG	4 cut(s)	521, 543, 1135, 1192
Bpu1102I	GCTNAGC	1 cut(s)	922
BpuEI	CTTGAG	1 cut(s)	200
BsaJI	CCNNGG	1 cut(s)	1116
BsaWI	WCCGGW	3 cut(s)	163, 703, 879
BsaXI	ACNNNNNCTCC	2 cut(s)	12, 42
Bsc4I	CCNNNNNNNGG	2 cut(s)	151, 1122
Bse118I	RCCGGY	2 cut(s)	703, 879
Bse3DI	GCAATG	1 cut(s)	404
BseAI	TCCGGA	1 cut(s)	163
BseBI	CCWGG	1 cut(s)	1071
BseDI	CCNNGG	1 cut(s)	1116
BseGI	GGATG	5 cut(s)	103, 156, 559, 664, 1108
BseLI	CCNNNNNNNGG	2 cut(s)	151, 1122
BseMI	GCAATG	1 cut(s)	404
BseMII	CTCAG	3 cut(s)	615, 656, 936
BseXI	GCAGC	2 cut(s)	49, 425
Bsh1236I	CGCG	2 cut(s)	752, 1220
BshTI	ACCGGT	2 cut(s)	703, 879
BsiHKAI	GWGCWC	1 cut(s)	643
BsiSI	CCGG	3 cut(s)	164, 704, 880
BslI	CCNNNNNNNGG	2 cut(s)	151, 1122
BsmAI	GTCTC	3 cut(s)	248, 624, 640
Bsp1286I	GDGCHC	2 cut(s)	643, 1208
Bsp13I	TCCGGA	1 cut(s)	163
Bsp143I	GATC	2 cut(s)	154, 844
Bsp1720I	GCTNAGC	1 cut(s)	922
BspACI	CCGC	2 cut(s)	1099, 1218
BspCNI	CTCAG	3 cut(s)	616, 655, 935
BspEI	TCCGGA	1 cut(s)	163
BspFNI	CGCG	2 cut(s)	752, 1220
BspLI	GGNNCC	4 cut(s)	156, 327, 1028, 1207
BspPI	GGATC	2 cut(s)	149, 162
BspQI	GCTCTTC	1 cut(s)	825
BsrDI	GCAATG	1 cut(s)	404
BsrFI	RCCGGY	2 cut(s)	703, 879
BssAI	RCCGGY	2 cut(s)	703, 879
BssECI	CCNNGG	1 cut(s)	1116
BssMI	GATC	2 cut(s)	154, 844
BssT1I	CCWWGG	1 cut(s)	1116
Bst2UI	CCWGG	1 cut(s)	1071
Bst4CI	ACNGT	1 cut(s)	358
Bst6I	CTCTTC	1 cut(s)	825
BstC8I	GCNNGC	3 cut(s)	411, 434, 946
BstDEI	CTNAG	5 cut(s)	624, 642, 922, 1046, 1064
BstF5I	GGATG	5 cut(s)	103, 156, 559, 664, 1108
BstFNI	CGCG	2 cut(s)	752, 1220
BstH2I	RGCGCY	1 cut(s)	1077
BstHHI	GCGC	3 cut(s)	432, 754, 1076
BstKTI	GATC	2 cut(s)	157, 847
BstMAI	GTCTC	3 cut(s)	248, 624, 640
BstMBI	GATC	2 cut(s)	154, 844
BstMWI	GCNNNNNNNGC	2 cut(s)	175, 1212
BstNI	CCWGG	1 cut(s)	1071
BstNSI	RCATGY	1 cut(s)	1018
BstSCI	CCNGG	1 cut(s)	1069
BstUI	CGCG	2 cut(s)	752, 1220
BstV1I	GCAGC	2 cut(s)	49, 425
BstV2I	GAAGAC	2 cut(s)	29, 817
BstX2I	RGATCY	1 cut(s)	154
BstYI	RGATCY	1 cut(s)	154
BtrI	CACGTC	1 cut(s)	383
BtsCI	GGATG	5 cut(s)	103, 156, 559, 664, 1108
BtsIMutI	CAGTG	1 cut(s)	33
Cac8I	GCNNGC	3 cut(s)	411, 434, 946
CfoI	GCGC	3 cut(s)	432, 754, 1076
Cfr10I	RCCGGY	2 cut(s)	703, 879
Cfr13I	GGNCC	1 cut(s)	386
Csp6I	GTAC	5 cut(s)	289, 445, 685, 883, 1126
CspAI	ACCGGT	2 cut(s)	703, 879
CviAII	CATG	4 cut(s)	226, 534, 928, 1015
CviQI	GTAC	5 cut(s)	289, 445, 685, 883, 1126
DdeI	CTNAG	5 cut(s)	624, 642, 922, 1046, 1064
DpnI	GATC	2 cut(s)	156, 846
DpnII	GATC	2 cut(s)	154, 844
Eam1104I	CTCTTC	1 cut(s)	825
EarI	CTCTTC	1 cut(s)	825
Ecl136II	GAGCTC	1 cut(s)	641
Eco130I	CCWWGG	1 cut(s)	1116
Eco24I	GRGCYC	2 cut(s)	643, 1208
Eco47I	GGWCC	1 cut(s)	386
Eco53kI	GAGCTC	1 cut(s)	641
Eco57I	CTGAAG	1 cut(s)	438
EcoICRI	GAGCTC	1 cut(s)	641
EcoRII	CCWGG	1 cut(s)	1069
EcoT14I	CCWWGG	1 cut(s)	1116
EcoT38I	GRGCYC	2 cut(s)	643, 1208
ErhI	CCWWGG	1 cut(s)	1116
FaeI	CATG	4 cut(s)	229, 537, 931, 1018
FalI	AAGNNNNNCTT	4 cut(s)	162, 194, 966, 998
FatI	CATG	4 cut(s)	225, 533, 927, 1014
FauI	CCCGC	1 cut(s)	1225
FbaI	TGATCA	1 cut(s)	844
Fnu4HI	GCNGC	2 cut(s)	63, 414
FokI	GGATG	5 cut(s)	90, 163, 566, 671, 1095
FriOI	GRGCYC	2 cut(s)	643, 1208
Fsp4HI	GCNGC	2 cut(s)	63, 414
FspBI	CTAG	1 cut(s)	236
GlaI	GCGC	3 cut(s)	431, 753, 1075
GluI	GCNGC	2 cut(s)	63, 414
GsuI	CTGGAG	4 cut(s)	521, 543, 1135, 1192
HaeII	RGCGCY	1 cut(s)	1077
HapII	CCGG	3 cut(s)	164, 704, 880
HhaI	GCGC	3 cut(s)	432, 754, 1076
Hin1II	CATG	4 cut(s)	229, 537, 931, 1018
Hin6I	GCGC	3 cut(s)	430, 752, 1074
HinP1I	GCGC	3 cut(s)	430, 752, 1074
HindIII	AAGCTT	3 cut(s)	309, 434, 719
HinfI	GANTC	2 cut(s)	666, 931
HpaII	CCGG	3 cut(s)	164, 704, 880
HphI	GGTGA	4 cut(s)	201, 617, 718, 1157
Hpy166II	GTNNAC	6 cut(s)	386, 445, 687, 885, 1165, 1173
Hpy188I	TCNGA	1 cut(s)	645
Hpy188III	TCNNGA	9 cut(s)	18, 164, 236, 329, 560, 623, 670, 1030, 1082
Hpy8I	GTNNAC	6 cut(s)	386, 445, 687, 885, 1165, 1173
HpyAV	CCTTC	4 cut(s)	170, 259, 649, 687
HpyCH4III	ACNGT	1 cut(s)	358
HpyCH4IV	ACGT	3 cut(s)	382, 839, 1188
HpyCH4V	TGCA	8 cut(s)	4, 31, 409, 470, 767, 799, 895, 959
HpyF10VI	GCNNNNNNNGC	2 cut(s)	175, 1212
HpyF3I	CTNAG	5 cut(s)	624, 642, 922, 1046, 1064
HpySE526I	ACGT	3 cut(s)	382, 839, 1188
Hsp92II	CATG	4 cut(s)	229, 537, 931, 1018
HspAI	GCGC	3 cut(s)	430, 752, 1074
Kpn2I	TCCGGA	1 cut(s)	163
Ksp22I	TGATCA	1 cut(s)	844
Kzo9I	GATC	2 cut(s)	154, 844
LguI	GCTCTTC	1 cut(s)	825
LmnI	GCTCC	5 cut(s)	166, 374, 562, 638, 1211
Lsp1109I	GCAGC	2 cut(s)	49, 425
LweI	GCATC	4 cut(s)	350, 410, 544, 946
MaeI	CTAG	1 cut(s)	236
MaeII	ACGT	3 cut(s)	382, 839, 1188
MaeIII	GTNAC	6 cut(s)	188, 207, 349, 475, 545, 706
MalI	GATC	2 cut(s)	156, 846
MboI	GATC	2 cut(s)	154, 844
MboII	GAAGA	5 cut(s)	29, 336, 431, 812, 822
MflI	RGATCY	1 cut(s)	154
MhlI	GDGCHC	2 cut(s)	643, 1208
MluCI	AATT	5 cut(s)	49, 300, 528, 587, 794
MmeI	TCCRAC	1 cut(s)	724
MnlI	CCTC	7 cut(s)	105, 141, 231, 399, 496, 834, 1159
MroI	TCCGGA	1 cut(s)	163
MseI	TTAA	3 cut(s)	438, 495, 792
MspA1I	CMGCKG	1 cut(s)	416
MspI	CCGG	3 cut(s)	164, 704, 880
MspR9I	CCNGG	1 cut(s)	1071
MvaI	CCWGG	1 cut(s)	1071
MvnI	CGCG	2 cut(s)	752, 1220
MwoI	GCNNNNNNNGC	2 cut(s)	175, 1212
NdeII	GATC	2 cut(s)	154, 844
NlaIII	CATG	4 cut(s)	229, 537, 931, 1018
NlaIV	GGNNCC	4 cut(s)	156, 327, 1028, 1207
NmuCI	GTSAC	2 cut(s)	207, 706
NspI	RCATGY	1 cut(s)	1018
PciI	ACATGT	1 cut(s)	1014
PciSI	GCTCTTC	1 cut(s)	825
PcsI	WCGNNNNNNNCGW	1 cut(s)	1134
PfeI	GAWTC	2 cut(s)	666, 931
PflMI	CCANNNNNTGG	2 cut(s)	151, 1122
PinAI	ACCGGT	2 cut(s)	703, 879
PkrI	GCNGC	2 cut(s)	64, 415
PscI	ACATGT	1 cut(s)	1014
Psp124BI	GAGCTC	1 cut(s)	643
Psp6I	CCWGG	1 cut(s)	1069
PspGI	CCWGG	1 cut(s)	1069
PspN4I	GGNNCC	4 cut(s)	156, 327, 1028, 1207
PspPI	GGNCC	1 cut(s)	386
PsuI	RGATCY	1 cut(s)	154
PvuII	CAGCTG	1 cut(s)	416
RsaI	GTAC	5 cut(s)	290, 446, 686, 884, 1127
RsaNI	GTAC	5 cut(s)	289, 445, 685, 883, 1126
SacI	GAGCTC	1 cut(s)	643
SapI	GCTCTTC	1 cut(s)	825
SaqAI	TTAA	3 cut(s)	438, 495, 792
SatI	GCNGC	2 cut(s)	63, 414
Sau3AI	GATC	2 cut(s)	154, 844
Sau96I	GGNCC	1 cut(s)	386
ScrFI	CCNGG	1 cut(s)	1071
SduI	GDGCHC	2 cut(s)	643, 1208
SfaNI	GCATC	4 cut(s)	350, 410, 544, 946
SinI	GGWCC	1 cut(s)	386
SmlI	CTYRAG	1 cut(s)	179
SmoI	CTYRAG	1 cut(s)	179
Sse9I	AATT	5 cut(s)	49, 300, 528, 587, 794
SsiI	CCGC	2 cut(s)	1099, 1218
SspMI	CTAG	1 cut(s)	236
SstI	GAGCTC	1 cut(s)	643
StyD4I	CCNGG	1 cut(s)	1069
StyI	CCWWGG	1 cut(s)	1116
TaaI	ACNGT	1 cut(s)	358
TaiI	ACGT	3 cut(s)	385, 842, 1191
TaqI	TCGA	2 cut(s)	453, 1243
TasI	AATT	5 cut(s)	49, 300, 528, 587, 794
TfiI	GAWTC	2 cut(s)	666, 931
Tru1I	TTAA	3 cut(s)	438, 495, 792
Tru9I	TTAA	3 cut(s)	438, 495, 792
TscAI	CASTG	1 cut(s)	33
TseFI	GTSAC	2 cut(s)	207, 706
TseI	GCWGC	2 cut(s)	62, 413
Tsp45I	GTSAC	2 cut(s)	207, 706
TspDTI	ATGAA	7 cut(s)	290, 473, 522, 669, 968, 1181, 1251
TspGWI	ACGGA	3 cut(s)	96, 951, 1199
TspRI	CASTG	1 cut(s)	33
Van91I	CCANNNNNTGG	2 cut(s)	151, 1122
VpaK11BI	GGWCC	1 cut(s)	386
XapI	RAATTY	1 cut(s)	49
XbaI	TCTAGA	1 cut(s)	235
XceI	RCATGY	1 cut(s)	1018
XspI	CTAG	1 cut(s)	236

Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.