Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region
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| Species | Orthologous Gene IDs |
|---|---|
| arabidopsis_thaliana | AT4G03120 |
| fragaria_vesca | FvH4_2g24650 |
| malus_domestica | MD03G1275200.v1.1 MD11G1297300.v1.1 |
| prunus_persica | Prupe.8G251800_v2.0.a1 Prupe.8G251800_v2.0.a1 |
| rosa_chinensis | RchiOBHm_Chr6g0292481 |
| rosa_laevigata | RLG00000012020 |
| rosa_multiflora | Rmu_sc0001354.1_g000026 Rmu_sc0020530.1_g000001 |
| rosa_roxburghii | Rroxscaffold_7G00175020 |
| rosa_rugosa | Rorug06G0227000 Rorug06G0227100 |
| rosa_samantha | Rh6AG340300 Rh6BG347600 Rh6CG354600 Rh6DG340400 |
| rosa_wichuraiana | Rw6G029630 |
| Enzyme | Recognition Site | Cut Count | Positions (bp) |
|---|---|---|---|
| AanI | TTATAA | 1 cut(s) | 84 |
| AccB7I | CCANNNNNTGG | 3 cut(s) | 145, 275, 569 |
| AciI | CCGC | 1 cut(s) | 380 |
| AcoI | YGGCCR | 2 cut(s) | 175, 187 |
| AcsI | RAATTY | 1 cut(s) | 119 |
| AcuI | CTGAAG | 1 cut(s) | 39 |
| AdeI | CACNNNGTG | 1 cut(s) | 410 |
| AfaI | GTAC | 1 cut(s) | 110 |
| AfiI | CCNNNNNNNGG | 5 cut(s) | 145, 275, 350, 523, 569 |
| AjnI | CCWGG | 8 cut(s) | 274, 292, 313, 349, 358, 406, 415, 424 |
| AluBI | AGCT | 4 cut(s) | 194, 200, 221, 356 |
| AluI | AGCT | 4 cut(s) | 194, 200, 221, 356 |
| Alw21I | GWGCWC | 4 cut(s) | 171, 304, 358, 415 |
| Alw44I | GTGCAC | 1 cut(s) | 300 |
| AlwNI | CAGNNNCTG | 1 cut(s) | 482 |
| AoxI | GGCC | 4 cut(s) | 175, 187, 323, 449 |
| ApaLI | GTGCAC | 1 cut(s) | 300 |
| ApeKI | GCWGC | 4 cut(s) | 194, 197, 218, 486 |
| ApoI | RAATTY | 1 cut(s) | 119 |
| ArsI | GACNNNNNNTTYG | 2 cut(s) | 31, 63 |
| AspLEI | GCGC | 1 cut(s) | 249 |
| AspS9I | GGNCC | 1 cut(s) | 310 |
| AvaII | GGWCC | 1 cut(s) | 310 |
| BaeGI | GKGCMC | 1 cut(s) | 304 |
| BalI | TGGCCA | 2 cut(s) | 177, 189 |
| BanII | GRGCYC | 1 cut(s) | 358 |
| BbsI | GAAGAC | 1 cut(s) | 248 |
| Bbv12I | GWGCWC | 4 cut(s) | 171, 304, 358, 415 |
| BbvI | GCAGC | 4 cut(s) | 181, 209, 230, 498 |
| BccI | CCATC | 2 cut(s) | 391, 575 |
| BciT130I | CCWGG | 8 cut(s) | 276, 294, 315, 351, 360, 408, 417, 426 |
| BfaI | CTAG | 1 cut(s) | 615 |
| BfmI | CTRYAG | 1 cut(s) | 195 |
| BfoI | RGCGCY | 1 cut(s) | 250 |
| BisI | GCNGC | 4 cut(s) | 195, 198, 219, 487 |
| BlpI | GCTNAGC | 1 cut(s) | 243 |
| BlsI | GCNGC | 4 cut(s) | 196, 199, 220, 488 |
| Bme1390I | CCNGG | 8 cut(s) | 276, 294, 315, 351, 360, 408, 417, 426 |
| Bme18I | GGWCC | 1 cut(s) | 310 |
| BmgT120I | GGNCC | 1 cut(s) | 310 |
| BmiI | GGNNCC | 3 cut(s) | 312, 402, 528 |
| BmrFI | CCNGG | 8 cut(s) | 276, 294, 315, 351, 360, 408, 417, 426 |
| BmsI | GCATC | 1 cut(s) | 378 |
| BpiI | GAAGAC | 1 cut(s) | 248 |
| BpmI | CTGGAG | 4 cut(s) | 312, 315, 342, 372 |
| Bpu1102I | GCTNAGC | 1 cut(s) | 243 |
| BsaJI | CCNNGG | 5 cut(s) | 5, 172, 184, 313, 314 |
| BsaXI | ACNNNNNCTCC | 2 cut(s) | 589, 619 |
| Bsc4I | CCNNNNNNNGG | 5 cut(s) | 145, 275, 350, 523, 569 |
| Bse1I | ACTGG | 1 cut(s) | 329 |
| BseBI | CCWGG | 8 cut(s) | 276, 294, 315, 351, 360, 408, 417, 426 |
| BseDI | CCNNGG | 5 cut(s) | 5, 172, 184, 313, 314 |
| BseGI | GGATG | 1 cut(s) | 324 |
| BseLI | CCNNNNNNNGG | 5 cut(s) | 145, 275, 350, 523, 569 |
| BseMII | CTCAG | 1 cut(s) | 257 |
| BseNI | ACTGG | 1 cut(s) | 329 |
| BseRI | GAGGAG | 1 cut(s) | 140 |
| BseSI | GKGCMC | 1 cut(s) | 304 |
| BseXI | GCAGC | 4 cut(s) | 181, 209, 230, 498 |
| BsgI | GTGCAG | 1 cut(s) | 237 |
| BshFI | GGCC | 4 cut(s) | 177, 189, 325, 451 |
| BsiHKAI | GWGCWC | 4 cut(s) | 171, 304, 358, 415 |
| BslFI | GGGAC | 2 cut(s) | 296, 500 |
| BslI | CCNNNNNNNGG | 5 cut(s) | 145, 275, 350, 523, 569 |
| BsmFI | GGGAC | 2 cut(s) | 296, 500 |
| BsmI | GAATGC | 1 cut(s) | 426 |
| BsnI | GGCC | 4 cut(s) | 177, 189, 325, 451 |
| Bsp1286I | GDGCHC | 4 cut(s) | 171, 304, 358, 415 |
| Bsp1720I | GCTNAGC | 1 cut(s) | 243 |
| BspACI | CCGC | 1 cut(s) | 380 |
| BspANI | GGCC | 4 cut(s) | 177, 189, 325, 451 |
| BspCNI | CTCAG | 1 cut(s) | 256 |
| BspLI | GGNNCC | 3 cut(s) | 312, 402, 528 |
| BspMAI | CTGCAG | 1 cut(s) | 199 |
| BsrI | ACTGG | 1 cut(s) | 329 |
| BssECI | CCNNGG | 5 cut(s) | 5, 172, 184, 313, 314 |
| BssT1I | CCWWGG | 2 cut(s) | 172, 184 |
| Bst2UI | CCWGG | 8 cut(s) | 276, 294, 315, 351, 360, 408, 417, 426 |
| Bst4CI | ACNGT | 2 cut(s) | 26, 478 |
| BstAPI | GCANNNNNTGC | 1 cut(s) | 500 |
| BstC8I | GCNNGC | 2 cut(s) | 179, 484 |
| BstDEI | CTNAG | 1 cut(s) | 243 |
| BstF5I | GGATG | 1 cut(s) | 324 |
| BstH2I | RGCGCY | 1 cut(s) | 250 |
| BstHHI | GCGC | 1 cut(s) | 249 |
| BstMWI | GCNNNNNNNGC | 3 cut(s) | 289, 388, 500 |
| BstNI | CCWGG | 8 cut(s) | 276, 294, 315, 351, 360, 408, 417, 426 |
| BstSCI | CCNGG | 8 cut(s) | 274, 292, 313, 349, 358, 406, 415, 424 |
| BstSFI | CTRYAG | 1 cut(s) | 195 |
| BstSLI | GKGCMC | 1 cut(s) | 304 |
| BstV1I | GCAGC | 4 cut(s) | 181, 209, 230, 498 |
| BstV2I | GAAGAC | 1 cut(s) | 248 |
| BstXI | CCANNNNNNTGG | 1 cut(s) | 185 |
| BsuRI | GGCC | 4 cut(s) | 177, 189, 325, 451 |
| BtsCI | GGATG | 1 cut(s) | 324 |
| Cac8I | GCNNGC | 2 cut(s) | 179, 484 |
| CaiI | CAGNNNCTG | 1 cut(s) | 482 |
| CfoI | GCGC | 1 cut(s) | 249 |
| Cfr13I | GGNCC | 1 cut(s) | 310 |
| CsiI | ACCWGGT | 2 cut(s) | 274, 406 |
| Csp6I | GTAC | 1 cut(s) | 109 |
| CviAII | CATG | 1 cut(s) | 385 |
| CviQI | GTAC | 1 cut(s) | 109 |
| DdeI | CTNAG | 1 cut(s) | 243 |
| DraIII | CACNNNGTG | 1 cut(s) | 410 |
| EaeI | YGGCCR | 2 cut(s) | 175, 187 |
| EciI | GGCGGA | 1 cut(s) | 369 |
| Ecl136II | GAGCTC | 1 cut(s) | 356 |
| Eco130I | CCWWGG | 2 cut(s) | 172, 184 |
| Eco147I | AGGCCT | 2 cut(s) | 325, 451 |
| Eco24I | GRGCYC | 1 cut(s) | 358 |
| Eco47I | GGWCC | 1 cut(s) | 310 |
| Eco53kI | GAGCTC | 1 cut(s) | 356 |
| Eco57I | CTGAAG | 1 cut(s) | 39 |
| EcoICRI | GAGCTC | 1 cut(s) | 356 |
| EcoRII | CCWGG | 8 cut(s) | 274, 292, 313, 349, 358, 406, 415, 424 |
| EcoT14I | CCWWGG | 2 cut(s) | 172, 184 |
| EcoT38I | GRGCYC | 1 cut(s) | 358 |
| ErhI | CCWWGG | 2 cut(s) | 172, 184 |
| FaeI | CATG | 1 cut(s) | 388 |
| FaiI | YATR | 8 cut(s) | 84, 281, 347, 369, 386, 461, 524, 579 |
| FaqI | GGGAC | 2 cut(s) | 296, 500 |
| FatI | CATG | 1 cut(s) | 384 |
| Fnu4HI | GCNGC | 4 cut(s) | 195, 198, 219, 487 |
| FokI | GGATG | 1 cut(s) | 331 |
| FriOI | GRGCYC | 1 cut(s) | 358 |
| Fsp4HI | GCNGC | 4 cut(s) | 195, 198, 219, 487 |
| FspBI | CTAG | 1 cut(s) | 615 |
| GlaI | GCGC | 1 cut(s) | 248 |
| GluI | GCNGC | 4 cut(s) | 195, 198, 219, 487 |
| GsuI | CTGGAG | 4 cut(s) | 312, 315, 342, 372 |
| HaeII | RGCGCY | 1 cut(s) | 250 |
| HaeIII | GGCC | 4 cut(s) | 177, 189, 325, 451 |
| HhaI | GCGC | 1 cut(s) | 249 |
| Hin1II | CATG | 1 cut(s) | 388 |
| Hin6I | GCGC | 1 cut(s) | 247 |
| HinP1I | GCGC | 1 cut(s) | 247 |
| HincII | GTYRAC | 1 cut(s) | 151 |
| HindII | GTYRAC | 1 cut(s) | 151 |
| HinfI | GANTC | 4 cut(s) | 47, 159, 463, 611 |
| Hpy166II | GTNNAC | 2 cut(s) | 151, 302 |
| Hpy188I | TCNGA | 2 cut(s) | 117, 444 |
| Hpy188III | TCNNGA | 1 cut(s) | 608 |
| Hpy8I | GTNNAC | 2 cut(s) | 151, 302 |
| HpyAV | CCTTC | 2 cut(s) | 63, 528 |
| HpyCH4III | ACNGT | 2 cut(s) | 26, 478 |
| HpyCH4IV | ACGT | 1 cut(s) | 99 |
| HpyCH4V | TGCA | 3 cut(s) | 197, 218, 302 |
| HpyF10VI | GCNNNNNNNGC | 3 cut(s) | 289, 388, 500 |
| HpyF3I | CTNAG | 1 cut(s) | 243 |
| HpySE526I | ACGT | 1 cut(s) | 99 |
| Hsp92II | CATG | 1 cut(s) | 388 |
| HspAI | GCGC | 1 cut(s) | 247 |
| LmnI | GCTCC | 8 cut(s) | 127, 166, 353, 361, 382, 406, 418, 532 |
| Lsp1109I | GCAGC | 4 cut(s) | 181, 209, 230, 498 |
| LweI | GCATC | 1 cut(s) | 378 |
| MabI | ACCWGGT | 2 cut(s) | 274, 406 |
| MaeI | CTAG | 1 cut(s) | 615 |
| MaeII | ACGT | 1 cut(s) | 99 |
| MaeIII | GTNAC | 2 cut(s) | 17, 26 |
| MboII | GAAGA | 1 cut(s) | 248 |
| MhlI | GDGCHC | 4 cut(s) | 171, 304, 358, 415 |
| MlsI | TGGCCA | 2 cut(s) | 177, 189 |
| MluCI | AATT | 2 cut(s) | 119, 431 |
| MluNI | TGGCCA | 2 cut(s) | 177, 189 |
| Mox20I | TGGCCA | 2 cut(s) | 177, 189 |
| MscI | TGGCCA | 2 cut(s) | 177, 189 |
| MseI | TTAA | 3 cut(s) | 236, 434, 588 |
| Msp20I | TGGCCA | 2 cut(s) | 177, 189 |
| MspR9I | CCNGG | 8 cut(s) | 276, 294, 315, 351, 360, 408, 417, 426 |
| Mva1269I | GAATGC | 1 cut(s) | 426 |
| MvaI | CCWGG | 8 cut(s) | 276, 294, 315, 351, 360, 408, 417, 426 |
| MwoI | GCNNNNNNNGC | 3 cut(s) | 289, 388, 500 |
| NlaIII | CATG | 1 cut(s) | 388 |
| NlaIV | GGNNCC | 3 cut(s) | 312, 402, 528 |
| NmuCI | GTSAC | 2 cut(s) | 17, 26 |
| PasI | CCCWGGG | 1 cut(s) | 314 |
| PceI | AGGCCT | 2 cut(s) | 325, 451 |
| PctI | GAATGC | 1 cut(s) | 426 |
| PfeI | GAWTC | 4 cut(s) | 47, 159, 463, 611 |
| PflMI | CCANNNNNTGG | 3 cut(s) | 145, 275, 569 |
| PfoI | TCCNGGA | 2 cut(s) | 358, 415 |
| PkrI | GCNGC | 4 cut(s) | 196, 199, 220, 488 |
| PsiI | TTATAA | 1 cut(s) | 84 |
| Psp124BI | GAGCTC | 1 cut(s) | 358 |
| Psp6I | CCWGG | 8 cut(s) | 274, 292, 313, 349, 358, 406, 415, 424 |
| PspGI | CCWGG | 8 cut(s) | 274, 292, 313, 349, 358, 406, 415, 424 |
| PspN4I | GGNNCC | 3 cut(s) | 312, 402, 528 |
| PspPI | GGNCC | 1 cut(s) | 310 |
| PstI | CTGCAG | 1 cut(s) | 199 |
| PstNI | CAGNNNCTG | 1 cut(s) | 482 |
| RsaI | GTAC | 1 cut(s) | 110 |
| RsaNI | GTAC | 1 cut(s) | 109 |
| SacI | GAGCTC | 1 cut(s) | 358 |
| SaqAI | TTAA | 3 cut(s) | 236, 434, 588 |
| SatI | GCNGC | 4 cut(s) | 195, 198, 219, 487 |
| Sau96I | GGNCC | 1 cut(s) | 310 |
| ScrFI | CCNGG | 8 cut(s) | 276, 294, 315, 351, 360, 408, 417, 426 |
| SduI | GDGCHC | 4 cut(s) | 171, 304, 358, 415 |
| SexAI | ACCWGGT | 2 cut(s) | 274, 406 |
| SfaNI | GCATC | 1 cut(s) | 378 |
| SfcI | CTRYAG | 1 cut(s) | 195 |
| SinI | GGWCC | 1 cut(s) | 310 |
| Sse9I | AATT | 2 cut(s) | 119, 431 |
| SseBI | AGGCCT | 2 cut(s) | 325, 451 |
| SsiI | CCGC | 1 cut(s) | 380 |
| SspMI | CTAG | 1 cut(s) | 615 |
| SstI | GAGCTC | 1 cut(s) | 358 |
| StuI | AGGCCT | 2 cut(s) | 325, 451 |
| StyD4I | CCNGG | 8 cut(s) | 274, 292, 313, 349, 358, 406, 415, 424 |
| StyI | CCWWGG | 2 cut(s) | 172, 184 |
| TaaI | ACNGT | 2 cut(s) | 26, 478 |
| TaiI | ACGT | 1 cut(s) | 102 |
| TasI | AATT | 2 cut(s) | 119, 431 |
| TatI | WGTACW | 1 cut(s) | 108 |
| TfiI | GAWTC | 4 cut(s) | 47, 159, 463, 611 |
| Tru1I | TTAA | 3 cut(s) | 236, 434, 588 |
| Tru9I | TTAA | 3 cut(s) | 236, 434, 588 |
| TseFI | GTSAC | 2 cut(s) | 17, 26 |
| TseI | GCWGC | 4 cut(s) | 194, 197, 218, 486 |
| Tsp45I | GTSAC | 2 cut(s) | 17, 26 |
| TspDTI | ATGAA | 1 cut(s) | 476 |
| Van91I | CCANNNNNTGG | 3 cut(s) | 145, 275, 569 |
| VneI | GTGCAC | 1 cut(s) | 300 |
| VpaK11BI | GGWCC | 1 cut(s) | 310 |
| XapI | RAATTY | 1 cut(s) | 119 |
| XspI | CTAG | 1 cut(s) | 615 |