Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region
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| Species | Orthologous Gene IDs |
|---|---|
| arabidopsis_thaliana | AT4G03120 |
| fragaria_vesca | FvH4_2g24650 |
| malus_domestica | MD03G1275200.v1.1 MD11G1297300.v1.1 |
| prunus_persica | Prupe.8G251800_v2.0.a1 Prupe.8G251800_v2.0.a1 |
| rosa_chinensis | RchiOBHm_Chr6g0292481 |
| rosa_laevigata | RLG00000012020 |
| rosa_multiflora | Rmu_sc0001354.1_g000026 Rmu_sc0020530.1_g000001 |
| rosa_roxburghii | Rroxscaffold_7G00175020 |
| rosa_rugosa | Rorug06G0227000 Rorug06G0227100 |
| rosa_samantha | Rh6AG340300 Rh6BG347600 Rh6CG354600 Rh6DG340400 |
| rosa_wichuraiana | Rw6G029630 |
| Enzyme | Recognition Site | Cut Count | Positions (bp) |
|---|---|---|---|
| AasI | GACNNNNNNGTC | 1 cut(s) | 333 |
| AccB1I | GGYRCC | 1 cut(s) | 500 |
| AccB7I | CCANNNNNTGG | 1 cut(s) | 329 |
| AccI | GTMKAC | 1 cut(s) | 357 |
| AciI | CCGC | 2 cut(s) | 77, 103 |
| AclWI | GGATC | 1 cut(s) | 586 |
| AcoI | YGGCCR | 1 cut(s) | 175 |
| AfaI | GTAC | 1 cut(s) | 110 |
| AfiI | CCNNNNNNNGG | 2 cut(s) | 329, 511 |
| AgsI | TTSAA | 1 cut(s) | 557 |
| AjnI | CCWGG | 8 cut(s) | 277, 298, 328, 349, 394, 403, 412, 574 |
| AluBI | AGCT | 2 cut(s) | 188, 209 |
| AluI | AGCT | 2 cut(s) | 188, 209 |
| Alw21I | GWGCWC | 1 cut(s) | 457 |
| AlwI | GGATC | 1 cut(s) | 586 |
| AoxI | GGCC | 3 cut(s) | 175, 233, 437 |
| ApeKI | GCWGC | 7 cut(s) | 67, 130, 185, 206, 474, 515, 592 |
| ArsI | GACNNNNNNTTYG | 2 cut(s) | 31, 63 |
| AspLEI | GCGC | 2 cut(s) | 206, 479 |
| AspS9I | GGNCC | 2 cut(s) | 284, 335 |
| AsuC2I | CCSGG | 1 cut(s) | 471 |
| AsuII | TTCGAA | 1 cut(s) | 61 |
| AvaII | GGWCC | 2 cut(s) | 284, 335 |
| BaeGI | GKGCMC | 1 cut(s) | 505 |
| BalI | TGGCCA | 1 cut(s) | 177 |
| BanI | GGYRCC | 1 cut(s) | 500 |
| BanII | GRGCYC | 1 cut(s) | 403 |
| BbsI | GAAGAC | 1 cut(s) | 605 |
| Bbv12I | GWGCWC | 1 cut(s) | 457 |
| BbvI | GCAGC | 7 cut(s) | 79, 142, 197, 218, 486, 502, 604 |
| BccI | CCATC | 2 cut(s) | 379, 469 |
| BciT130I | CCWGG | 8 cut(s) | 279, 300, 330, 351, 396, 405, 414, 576 |
| BcnI | CCSGG | 1 cut(s) | 471 |
| BfaI | CTAG | 1 cut(s) | 539 |
| BfmI | CTRYAG | 1 cut(s) | 183 |
| BisI | GCNGC | 8 cut(s) | 68, 104, 131, 186, 207, 475, 516, 593 |
| BlsI | GCNGC | 8 cut(s) | 69, 105, 132, 187, 208, 476, 517, 594 |
| BmcAI | AGTACT | 1 cut(s) | 110 |
| Bme1390I | CCNGG | 9 cut(s) | 279, 300, 330, 351, 396, 405, 414, 471, 576 |
| Bme18I | GGWCC | 2 cut(s) | 284, 335 |
| BmgT120I | GGNCC | 2 cut(s) | 284, 335 |
| BmiI | GGNNCC | 5 cut(s) | 297, 348, 390, 402, 502 |
| BmrFI | CCNGG | 9 cut(s) | 279, 300, 330, 351, 396, 405, 414, 471, 576 |
| BmsI | GCATC | 4 cut(s) | 229, 255, 366, 399 |
| BpiI | GAAGAC | 1 cut(s) | 605 |
| BpmI | CTGGAG | 4 cut(s) | 282, 300, 333, 351 |
| Bpu14I | TTCGAA | 1 cut(s) | 61 |
| BpuMI | CCSGG | 1 cut(s) | 471 |
| BsaAI | YACGTR | 1 cut(s) | 33 |
| BsaJI | CCNNGG | 4 cut(s) | 5, 299, 395, 404 |
| Bsc4I | CCNNNNNNNGG | 2 cut(s) | 329, 511 |
| BseBI | CCWGG | 8 cut(s) | 279, 300, 330, 351, 396, 405, 414, 576 |
| BseDI | CCNNGG | 4 cut(s) | 5, 299, 395, 404 |
| BseGI | GGATG | 1 cut(s) | 414 |
| BseLI | CCNNNNNNNGG | 2 cut(s) | 329, 511 |
| BseMII | CTCAG | 1 cut(s) | 152 |
| BseRI | GAGGAG | 1 cut(s) | 140 |
| BseSI | GKGCMC | 1 cut(s) | 505 |
| BseXI | GCAGC | 7 cut(s) | 79, 142, 197, 218, 486, 502, 604 |
| BsgI | GTGCAG | 1 cut(s) | 501 |
| BshFI | GGCC | 3 cut(s) | 177, 235, 439 |
| BshNI | GGYRCC | 1 cut(s) | 500 |
| BsiHKAI | GWGCWC | 1 cut(s) | 457 |
| BsiSI | CCGG | 1 cut(s) | 471 |
| BslI | CCNNNNNNNGG | 2 cut(s) | 329, 511 |
| BsnI | GGCC | 3 cut(s) | 177, 235, 439 |
| Bsp119I | TTCGAA | 1 cut(s) | 61 |
| Bsp1286I | GDGCHC | 3 cut(s) | 403, 457, 505 |
| Bsp143I | GATC | 1 cut(s) | 578 |
| BspACI | CCGC | 2 cut(s) | 77, 103 |
| BspANI | GGCC | 3 cut(s) | 177, 235, 439 |
| BspCNI | CTCAG | 1 cut(s) | 151 |
| BspLI | GGNNCC | 5 cut(s) | 297, 348, 390, 402, 502 |
| BspMAI | CTGCAG | 1 cut(s) | 187 |
| BspPI | GGATC | 1 cut(s) | 586 |
| BspT104I | TTCGAA | 1 cut(s) | 61 |
| BspT107I | GGYRCC | 1 cut(s) | 500 |
| BssECI | CCNNGG | 4 cut(s) | 5, 299, 395, 404 |
| BssMI | GATC | 1 cut(s) | 578 |
| BssNAI | GTATAC | 1 cut(s) | 358 |
| Bst1107I | GTATAC | 1 cut(s) | 358 |
| Bst2UI | CCWGG | 8 cut(s) | 279, 300, 330, 351, 396, 405, 414, 576 |
| Bst4CI | ACNGT | 1 cut(s) | 500 |
| Bst6I | CTCTTC | 1 cut(s) | 590 |
| BstBAI | YACGTR | 1 cut(s) | 33 |
| BstBI | TTCGAA | 1 cut(s) | 61 |
| BstDEI | CTNAG | 1 cut(s) | 138 |
| BstF5I | GGATG | 1 cut(s) | 414 |
| BstHHI | GCGC | 2 cut(s) | 206, 479 |
| BstKTI | GATC | 1 cut(s) | 581 |
| BstMBI | GATC | 1 cut(s) | 578 |
| BstMWI | GCNNNNNNNGC | 2 cut(s) | 24, 274 |
| BstNI | CCWGG | 8 cut(s) | 279, 300, 330, 351, 396, 405, 414, 576 |
| BstSCI | CCNGG | 9 cut(s) | 277, 298, 328, 349, 394, 403, 412, 469, 574 |
| BstSFI | CTRYAG | 1 cut(s) | 183 |
| BstSLI | GKGCMC | 1 cut(s) | 505 |
| BstSNI | TACGTA | 1 cut(s) | 33 |
| BstV1I | GCAGC | 7 cut(s) | 79, 142, 197, 218, 486, 502, 604 |
| BstV2I | GAAGAC | 1 cut(s) | 605 |
| BstZ17I | GTATAC | 1 cut(s) | 358 |
| BsuRI | GGCC | 3 cut(s) | 177, 235, 439 |
| BtgZI | GCGATG | 1 cut(s) | 578 |
| BtsCI | GGATG | 1 cut(s) | 414 |
| BtsIMutI | CAGTG | 1 cut(s) | 550 |
| CfoI | GCGC | 2 cut(s) | 206, 479 |
| Cfr13I | GGNCC | 2 cut(s) | 284, 335 |
| Csp6I | GTAC | 1 cut(s) | 109 |
| CviAII | CATG | 3 cut(s) | 373, 433, 621 |
| CviQI | GTAC | 1 cut(s) | 109 |
| DdeI | CTNAG | 1 cut(s) | 138 |
| DpnI | GATC | 1 cut(s) | 580 |
| DpnII | GATC | 1 cut(s) | 578 |
| DrdI | GACNNNNNNGTC | 1 cut(s) | 333 |
| DseDI | GACNNNNNNGTC | 1 cut(s) | 333 |
| EaeI | YGGCCR | 1 cut(s) | 175 |
| Eam1104I | CTCTTC | 1 cut(s) | 590 |
| EarI | CTCTTC | 1 cut(s) | 590 |
| Eco105I | TACGTA | 1 cut(s) | 33 |
| Eco147I | AGGCCT | 1 cut(s) | 439 |
| Eco24I | GRGCYC | 1 cut(s) | 403 |
| Eco47I | GGWCC | 2 cut(s) | 284, 335 |
| EcoRII | CCWGG | 8 cut(s) | 277, 298, 328, 349, 394, 403, 412, 574 |
| EcoT38I | GRGCYC | 1 cut(s) | 403 |
| FaeI | CATG | 3 cut(s) | 376, 436, 624 |
| FaiI | YATR | 5 cut(s) | 263, 358, 374, 434, 622 |
| FatI | CATG | 3 cut(s) | 372, 432, 620 |
| FauI | CCCGC | 1 cut(s) | 70 |
| FblI | GTMKAC | 1 cut(s) | 357 |
| Fnu4HI | GCNGC | 8 cut(s) | 68, 104, 131, 186, 207, 475, 516, 593 |
| FokI | GGATG | 1 cut(s) | 421 |
| FriOI | GRGCYC | 1 cut(s) | 403 |
| Fsp4HI | GCNGC | 8 cut(s) | 68, 104, 131, 186, 207, 475, 516, 593 |
| FspBI | CTAG | 1 cut(s) | 539 |
| GlaI | GCGC | 2 cut(s) | 205, 478 |
| GluI | GCNGC | 8 cut(s) | 68, 104, 131, 186, 207, 475, 516, 593 |
| GsuI | CTGGAG | 4 cut(s) | 282, 300, 333, 351 |
| HaeIII | GGCC | 3 cut(s) | 177, 235, 439 |
| HapII | CCGG | 1 cut(s) | 471 |
| HhaI | GCGC | 2 cut(s) | 206, 479 |
| Hin1II | CATG | 3 cut(s) | 376, 436, 624 |
| Hin6I | GCGC | 2 cut(s) | 204, 477 |
| HinP1I | GCGC | 2 cut(s) | 204, 477 |
| HinfI | GANTC | 2 cut(s) | 47, 535 |
| HpaII | CCGG | 1 cut(s) | 471 |
| Hpy166II | GTNNAC | 3 cut(s) | 287, 338, 358 |
| Hpy188I | TCNGA | 1 cut(s) | 141 |
| Hpy188III | TCNNGA | 1 cut(s) | 532 |
| Hpy8I | GTNNAC | 3 cut(s) | 287, 338, 358 |
| HpyAV | CCTTC | 2 cut(s) | 63, 516 |
| HpyCH4III | ACNGT | 1 cut(s) | 500 |
| HpyCH4IV | ACGT | 1 cut(s) | 32 |
| HpyCH4V | TGCA | 4 cut(s) | 185, 379, 518, 592 |
| HpyF10VI | GCNNNNNNNGC | 2 cut(s) | 24, 274 |
| HpyF3I | CTNAG | 1 cut(s) | 138 |
| HpySE526I | ACGT | 1 cut(s) | 32 |
| Hsp92II | CATG | 3 cut(s) | 376, 436, 624 |
| HspAI | GCGC | 2 cut(s) | 204, 477 |
| Kzo9I | GATC | 1 cut(s) | 578 |
| LmnI | GCTCC | 6 cut(s) | 127, 301, 352, 394, 406, 460 |
| Lsp1109I | GCAGC | 7 cut(s) | 79, 142, 197, 218, 486, 502, 604 |
| LweI | GCATC | 4 cut(s) | 229, 255, 366, 399 |
| MaeI | CTAG | 1 cut(s) | 539 |
| MaeII | ACGT | 1 cut(s) | 32 |
| MaeIII | GTNAC | 1 cut(s) | 80 |
| MalI | GATC | 1 cut(s) | 580 |
| MboI | GATC | 1 cut(s) | 578 |
| MboII | GAAGA | 2 cut(s) | 577, 605 |
| MfeI | CAATTG | 1 cut(s) | 557 |
| MhlI | GDGCHC | 3 cut(s) | 403, 457, 505 |
| MlsI | TGGCCA | 1 cut(s) | 177 |
| MluCI | AATT | 2 cut(s) | 119, 557 |
| MluNI | TGGCCA | 1 cut(s) | 177 |
| MmeI | TCCRAC | 1 cut(s) | 584 |
| MnlI | CCTC | 8 cut(s) | 15, 118, 246, 275, 326, 429, 450, 539 |
| Mox20I | TGGCCA | 1 cut(s) | 177 |
| MscI | TGGCCA | 1 cut(s) | 177 |
| MseI | TTAA | 1 cut(s) | 162 |
| Msp20I | TGGCCA | 1 cut(s) | 177 |
| MspI | CCGG | 1 cut(s) | 471 |
| MspR9I | CCNGG | 9 cut(s) | 279, 300, 330, 351, 396, 405, 414, 471, 576 |
| MunI | CAATTG | 1 cut(s) | 557 |
| MvaI | CCWGG | 8 cut(s) | 279, 300, 330, 351, 396, 405, 414, 576 |
| MwoI | GCNNNNNNNGC | 2 cut(s) | 24, 274 |
| NciI | CCSGG | 1 cut(s) | 471 |
| NdeII | GATC | 1 cut(s) | 578 |
| NlaIII | CATG | 3 cut(s) | 376, 436, 624 |
| NlaIV | GGNNCC | 5 cut(s) | 297, 348, 390, 402, 502 |
| NmeAIII | GCCGAG | 1 cut(s) | 211 |
| NspV | TTCGAA | 1 cut(s) | 61 |
| PceI | AGGCCT | 1 cut(s) | 439 |
| PfeI | GAWTC | 2 cut(s) | 47, 535 |
| PflMI | CCANNNNNTGG | 1 cut(s) | 329 |
| PfoI | TCCNGGA | 1 cut(s) | 349 |
| PkrI | GCNGC | 8 cut(s) | 69, 105, 132, 187, 208, 476, 517, 594 |
| Ppu21I | YACGTR | 1 cut(s) | 33 |
| Psp6I | CCWGG | 8 cut(s) | 277, 298, 328, 349, 394, 403, 412, 574 |
| PspGI | CCWGG | 8 cut(s) | 277, 298, 328, 349, 394, 403, 412, 574 |
| PspN4I | GGNNCC | 5 cut(s) | 297, 348, 390, 402, 502 |
| PspPI | GGNCC | 2 cut(s) | 284, 335 |
| PstI | CTGCAG | 1 cut(s) | 187 |
| RsaI | GTAC | 1 cut(s) | 110 |
| RsaNI | GTAC | 1 cut(s) | 109 |
| SaqAI | TTAA | 1 cut(s) | 162 |
| SatI | GCNGC | 8 cut(s) | 68, 104, 131, 186, 207, 475, 516, 593 |
| Sau3AI | GATC | 1 cut(s) | 578 |
| Sau96I | GGNCC | 2 cut(s) | 284, 335 |
| ScaI | AGTACT | 1 cut(s) | 110 |
| ScrFI | CCNGG | 9 cut(s) | 279, 300, 330, 351, 396, 405, 414, 471, 576 |
| SduI | GDGCHC | 3 cut(s) | 403, 457, 505 |
| SetI | ASST | 7 cut(s) | 35, 190, 211, 286, 331, 337, 397 |
| SfaNI | GCATC | 4 cut(s) | 229, 255, 366, 399 |
| SfcI | CTRYAG | 1 cut(s) | 183 |
| SfuI | TTCGAA | 1 cut(s) | 61 |
| SinI | GGWCC | 2 cut(s) | 284, 335 |
| SnaBI | TACGTA | 1 cut(s) | 33 |
| Sse9I | AATT | 2 cut(s) | 119, 557 |
| SseBI | AGGCCT | 1 cut(s) | 439 |
| SsiI | CCGC | 2 cut(s) | 77, 103 |
| SspI | AATATT | 1 cut(s) | 427 |
| SspMI | CTAG | 1 cut(s) | 539 |
| StuI | AGGCCT | 1 cut(s) | 439 |
| StyD4I | CCNGG | 9 cut(s) | 277, 298, 328, 349, 394, 403, 412, 469, 574 |
| TaaI | ACNGT | 1 cut(s) | 500 |
| TaiI | ACGT | 1 cut(s) | 35 |
| TaqI | TCGA | 2 cut(s) | 61, 238 |
| TasI | AATT | 2 cut(s) | 119, 557 |
| TatI | WGTACW | 1 cut(s) | 108 |
| TauI | GCSGC | 1 cut(s) | 106 |
| TfiI | GAWTC | 2 cut(s) | 47, 535 |
| Tru1I | TTAA | 1 cut(s) | 162 |
| Tru9I | TTAA | 1 cut(s) | 162 |
| TscAI | CASTG | 1 cut(s) | 550 |
| TseI | GCWGC | 7 cut(s) | 67, 130, 185, 206, 474, 515, 592 |
| TspRI | CASTG | 1 cut(s) | 550 |
| Van91I | CCANNNNNTGG | 1 cut(s) | 329 |
| VpaK11BI | GGWCC | 2 cut(s) | 284, 335 |
| XmiI | GTMKAC | 1 cut(s) | 357 |
| XspI | CTAG | 1 cut(s) | 539 |
| ZrmI | AGTACT | 1 cut(s) | 110 |