pycom04g20270

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
pyrus_communis
Chr4
OG0012738
Physical Location & Seq
Forward (+)
21789398 .. 21789883
486 bp
Loading structure...
UTR
Exon/CDS
Intron
pycom04g20270.1

Sequence Viewer

Length: 486 bp
ATGAAGGCGGGTCGAGTTGTAATGGAGTTATTTGCTGACAAAACCCCGAAAACTGCTGAAAATTTCCGCGCTCTTTGCACTGGAGATAAAGGGATTGGATTATCAGGGAAGCCACTGCACTTTAAGGGCTCCACATTTCATCGCATTATCCCGAACTTCATGTGCCAGGGTGGAGATTTTACAAGAGGCAATGGGATCGGAGGAGAGTCAATTTATGGGGCAAAATTTGAAGATGAGAACTTCAACTTGAAGCATACCGGCCCTGGAATTTTGTCGATGGCGAATGCTGGACCTAATACCAATGGTTCGCAGTTCTTCATTTGCACTGCAAGAACCCCATGGCTTGACGGAAAGCACGTTGTGTTTGGAAAAGTTGTTGATGGATACAGTGTTGTTGAGAAAATGGAGAAGGTGGGTTCGGAGAGCGGGACTACTTCTGAACCTGTTGTGATTGAAGACTGCGGCCAGGTAAAAGACGAGTGTTGA

Protein Analysis

162

Amino Acids

17.3

Weight (kDa)

6.42

Isoelectric Point (pI)

12.68

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
Pro_isomerase PF00160 3 - 155 5.7e-50 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
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Orthologous Genes (Group: OG0012738)

Species Orthologous Gene IDs
arabidopsis_thaliana AT3G56070 AT3G56070
fragaria_vesca FvH4_4g00620 FvH4_4g00620 FvH4_6g02290
malus_domestica MD04G1228500.v1.1
prunus_persica Prupe.6G348500_v2.0.a1
pyrus_communis pycom04g20270 pycom12g22510
rosa_chinensis RchiOBHm_Chr3g0450041
rosa_laevigata RLG00000025762 RLG00000025763
rosa_multiflora Rmu_sc0002646.1_g000022
rosa_roxburghii Rroxscaffold_6G00427830
rosa_rugosa Rorug02G0625000
rosa_samantha Rh3BG024700 Rh3DG024700
rosa_wichuraiana Rw3G001920

Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AccBSI CCGCTC 1 cut(s) 426
AccII CGCG 1 cut(s) 69
AciI CCGC 4 cut(s) 8, 67, 426, 462
AclWI GGATC 1 cut(s) 203
AcoI YGGCCR 1 cut(s) 463
AcsI RAATTY 3 cut(s) 61, 224, 267
AdeI CACNNNGTG 1 cut(s) 361
AgsI TTSAA 4 cut(s) 230, 244, 250, 455
AjnI CCWGG 3 cut(s) 165, 262, 465
AlwI GGATC 1 cut(s) 203
AoxI GGCC 2 cut(s) 259, 463
ApoI RAATTY 3 cut(s) 61, 224, 267
AspLEI GCGC 1 cut(s) 71
AspS9I GGNCC 2 cut(s) 260, 290
AvaII GGWCC 1 cut(s) 290
BanII GRGCYC 1 cut(s) 131
BbsI GAAGAC 1 cut(s) 462
BccI CCATC 2 cut(s) 271, 374
BcgI CGANNNNNNTGC 2 cut(s) 178, 212
BciT130I CCWGG 3 cut(s) 167, 264, 467
BciVI GTATCC 1 cut(s) 377
BfuI GTATCC 1 cut(s) 377
BisI GCNGC 1 cut(s) 463
BlsI GCNGC 1 cut(s) 464
Bme1390I CCNGG 3 cut(s) 167, 264, 467
Bme18I GGWCC 1 cut(s) 290
BmgT120I GGNCC 2 cut(s) 260, 290
BmiI GGNNCC 1 cut(s) 130
BmrFI CCNGG 3 cut(s) 167, 264, 467
BpiI GAAGAC 1 cut(s) 462
BpmI CTGGAG 1 cut(s) 102
BsaJI CCNNGG 3 cut(s) 166, 262, 338
Bse118I RCCGGY 1 cut(s) 257
Bse1I ACTGG 1 cut(s) 85
Bse3DI GCAATG 1 cut(s) 196
BseBI CCWGG 3 cut(s) 167, 264, 467
BseDI CCNNGG 3 cut(s) 166, 262, 338
BseMI GCAATG 1 cut(s) 196
BseNI ACTGG 1 cut(s) 85
BseRI GAGGAG 1 cut(s) 216
BsgI GTGCAG 1 cut(s) 101
Bsh1236I CGCG 1 cut(s) 69
BshFI GGCC 2 cut(s) 261, 465
BsiSI CCGG 1 cut(s) 258
BslFI GGGAC 1 cut(s) 442
BsmFI GGGAC 1 cut(s) 442
BsmI GAATGC 1 cut(s) 289
BsnI GGCC 2 cut(s) 261, 465
Bsp1286I GDGCHC 1 cut(s) 131
Bsp143I GATC 1 cut(s) 195
Bsp19I CCATGG 1 cut(s) 338
BspACI CCGC 4 cut(s) 8, 67, 426, 462
BspANI GGCC 2 cut(s) 261, 465
BspFNI CGCG 1 cut(s) 69
BspLI GGNNCC 1 cut(s) 130
BspPI GGATC 1 cut(s) 203
BsrBI CCGCTC 1 cut(s) 426
BsrDI GCAATG 1 cut(s) 196
BsrFI RCCGGY 1 cut(s) 257
BsrI ACTGG 1 cut(s) 85
BssAI RCCGGY 1 cut(s) 257
BssECI CCNNGG 3 cut(s) 166, 262, 338
BssMI GATC 1 cut(s) 195
BssT1I CCWWGG 1 cut(s) 338
Bst2UI CCWGG 3 cut(s) 167, 264, 467
Bst4CI ACNGT 1 cut(s) 389
BstDSI CCRYGG 1 cut(s) 338
BstFNI CGCG 1 cut(s) 69
BstHHI GCGC 1 cut(s) 71
BstKTI GATC 1 cut(s) 198
BstMBI GATC 1 cut(s) 195
BstMWI GCNNNNNNNGC 1 cut(s) 75
BstNI CCWGG 3 cut(s) 167, 264, 467
BstSCI CCNGG 3 cut(s) 165, 262, 465
BstUI CGCG 1 cut(s) 69
BstV2I GAAGAC 1 cut(s) 462
BsuI GTATCC 1 cut(s) 377
BsuRI GGCC 2 cut(s) 261, 465
BtgI CCRYGG 1 cut(s) 338
BtgZI GCGATG 1 cut(s) 125
BtsI GCAGTG 2 cut(s) 113, 324
BtsIMutI CAGTG 4 cut(s) 78, 113, 324, 394
CfoI GCGC 1 cut(s) 71
Cfr10I RCCGGY 1 cut(s) 257
Cfr13I GGNCC 2 cut(s) 260, 290
CviAII CATG 2 cut(s) 160, 339
CviJI RGCY 5 cut(s) 112, 129, 261, 343, 465
CviKI_1 RGCY 5 cut(s) 112, 129, 261, 343, 465
DpnI GATC 1 cut(s) 197
DpnII GATC 1 cut(s) 195
DraIII CACNNNGTG 1 cut(s) 361
EaeI YGGCCR 1 cut(s) 463
Eco130I CCWWGG 1 cut(s) 338
Eco24I GRGCYC 1 cut(s) 131
Eco47I GGWCC 1 cut(s) 290
EcoRII CCWGG 3 cut(s) 165, 262, 465
EcoT14I CCWWGG 1 cut(s) 338
EcoT38I GRGCYC 1 cut(s) 131
ErhI CCWWGG 1 cut(s) 338
FaeI CATG 2 cut(s) 163, 342
FaiI YATR 4 cut(s) 161, 216, 255, 340
FaqI GGGAC 1 cut(s) 442
FatI CATG 2 cut(s) 159, 338
FauI CCCGC 1 cut(s) 419
Fnu4HI GCNGC 1 cut(s) 463
FriOI GRGCYC 1 cut(s) 131
Fsp4HI GCNGC 1 cut(s) 463
GlaI GCGC 1 cut(s) 70
GluI GCNGC 1 cut(s) 463
GsuI CTGGAG 1 cut(s) 102
HaeIII GGCC 2 cut(s) 261, 465
HapII CCGG 1 cut(s) 258
HhaI GCGC 1 cut(s) 71
Hin1II CATG 2 cut(s) 163, 342
Hin6I GCGC 1 cut(s) 69
HinP1I GCGC 1 cut(s) 69
HinfI GANTC 1 cut(s) 206
HpaII CCGG 1 cut(s) 258
Hpy188I TCNGA 3 cut(s) 200, 421, 439
Hpy188III TCNNGA 1 cut(s) 151
HpyAV CCTTC 1 cut(s) 403
HpyCH4III ACNGT 1 cut(s) 389
HpyCH4IV ACGT 1 cut(s) 357
HpyCH4V TGCA 4 cut(s) 78, 118, 324, 329
HpyF10VI GCNNNNNNNGC 1 cut(s) 75
HpySE526I ACGT 1 cut(s) 357
Hsp92II CATG 2 cut(s) 163, 342
HspAI GCGC 1 cut(s) 69
Kzo9I GATC 1 cut(s) 195
LmnI GCTCC 1 cut(s) 134
MaeII ACGT 1 cut(s) 357
MalI GATC 1 cut(s) 197
MbiI CCGCTC 1 cut(s) 426
MboI GATC 1 cut(s) 195
MboII GAAGA 3 cut(s) 242, 307, 467
MhlI GDGCHC 1 cut(s) 131
MluCI AATT 4 cut(s) 61, 210, 224, 267
MlyI GAGTC 1 cut(s) 215
MnlI CCTC 2 cut(s) 179, 194
MseI TTAA 1 cut(s) 123
MspI CCGG 1 cut(s) 258
MspR9I CCNGG 3 cut(s) 167, 264, 467
Mva1269I GAATGC 1 cut(s) 289
MvaI CCWGG 3 cut(s) 167, 264, 467
MvnI CGCG 1 cut(s) 69
MwoI GCNNNNNNNGC 1 cut(s) 75
NcoI CCATGG 1 cut(s) 338
NdeII GATC 1 cut(s) 195
NlaIII CATG 2 cut(s) 163, 342
NlaIV GGNNCC 1 cut(s) 130
PcsI WCGNNNNNNNCGW 1 cut(s) 354
PctI GAATGC 1 cut(s) 289
PkrI GCNGC 1 cut(s) 464
PleI GAGTC 1 cut(s) 214
PpsI GAGTC 1 cut(s) 214
Psp6I CCWGG 3 cut(s) 165, 262, 465
PspGI CCWGG 3 cut(s) 165, 262, 465
PspN4I GGNNCC 1 cut(s) 130
PspPI GGNCC 2 cut(s) 260, 290
SaqAI TTAA 1 cut(s) 123
SatI GCNGC 1 cut(s) 463
Sau3AI GATC 1 cut(s) 195
Sau96I GGNCC 2 cut(s) 260, 290
SchI GAGTC 1 cut(s) 215
ScrFI CCNGG 3 cut(s) 167, 264, 467
SduI GDGCHC 1 cut(s) 131
SetI ASST 5 cut(s) 295, 360, 414, 445, 471
SinI GGWCC 1 cut(s) 290
Sse9I AATT 4 cut(s) 61, 210, 224, 267
SsiI CCGC 4 cut(s) 8, 67, 426, 462
StyD4I CCNGG 3 cut(s) 165, 262, 465
StyI CCWWGG 1 cut(s) 338
TaaI ACNGT 1 cut(s) 389
TaiI ACGT 1 cut(s) 360
TaqI TCGA 2 cut(s) 13, 275
TasI AATT 4 cut(s) 61, 210, 224, 267
TauI GCSGC 1 cut(s) 465
Tru1I TTAA 1 cut(s) 123
Tru9I TTAA 1 cut(s) 123
TscAI CASTG 4 cut(s) 85, 120, 331, 394
TspDTI ATGAA 4 cut(s) 17, 128, 148, 307
TspGWI ACGGA 1 cut(s) 363
TspRI CASTG 4 cut(s) 85, 120, 331, 394
VpaK11BI GGWCC 1 cut(s) 290
XapI RAATTY 3 cut(s) 61, 224, 267
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.