The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins. Some of these proteins have been shown both in vivo and in vitro to have ubiquitin E3 ligase activity.
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| Species | Orthologous Gene IDs |
|---|---|
| arabidopsis_thaliana | AT2G34200 AT2G34200 |
| fragaria_vesca | FvH4_3g07460 |
| malus_domestica | MD10G1277000.v1.1 |
| prunus_persica | Prupe.4G064900_v2.0.a1 Prupe.4G064900_v2.0.a1 |
| pyrus_communis | pycom05g27540 pycom10g23130 |
| rosa_chinensis | RchiOBHm_Chr5g0011391 |
| rosa_laevigata | RLG00000031829 |
| rosa_multiflora | Rmu_sc0009975.1_g000013 |
| rosa_roxburghii | Rroxscaffold_1G00065060 |
| rosa_rugosa | Rorug04G0456800 |
| rosa_samantha | Rh5AG088500 Rh5BG083600 Rh5CG096900 Rh5DG083500 |
| rosa_wichuraiana | Rw5G007680 |
| Enzyme | Recognition Site | Cut Count | Positions (bp) |
|---|---|---|---|
| Acc65I | GGTACC | 1 cut(s) | 268 |
| AccB1I | GGYRCC | 2 cut(s) | 268, 457 |
| AccI | GTMKAC | 1 cut(s) | 365 |
| AccII | CGCG | 1 cut(s) | 740 |
| AciI | CCGC | 3 cut(s) | 246, 581, 738 |
| AcoI | YGGCCR | 1 cut(s) | 247 |
| AcsI | RAATTY | 2 cut(s) | 301, 565 |
| AfaI | GTAC | 2 cut(s) | 270, 900 |
| AfiI | CCNNNNNNNGG | 1 cut(s) | 690 |
| AflIII | ACRYGT | 1 cut(s) | 716 |
| AgsI | TTSAA | 3 cut(s) | 125, 357, 632 |
| AjiI | CACGTC | 1 cut(s) | 717 |
| AluBI | AGCT | 3 cut(s) | 293, 658, 893 |
| AluI | AGCT | 3 cut(s) | 293, 658, 893 |
| Alw26I | GTCTC | 3 cut(s) | 101, 329, 728 |
| AoxI | GGCC | 2 cut(s) | 247, 850 |
| ApoI | RAATTY | 2 cut(s) | 301, 565 |
| AseI | ATTAAT | 2 cut(s) | 351, 434 |
| Asp700I | GAANNNNTTC | 1 cut(s) | 926 |
| Asp718I | GGTACC | 1 cut(s) | 268 |
| AspLEI | GCGC | 1 cut(s) | 742 |
| AsuC2I | CCSGG | 1 cut(s) | 10 |
| AsuHPI | GGTGA | 3 cut(s) | 139, 570, 898 |
| AsuII | TTCGAA | 1 cut(s) | 305 |
| BanI | GGYRCC | 2 cut(s) | 268, 457 |
| BccI | CCATC | 2 cut(s) | 314, 567 |
| BciVI | GTATCC | 1 cut(s) | 847 |
| BclI | TGATCA | 1 cut(s) | 55 |
| BcnI | CCSGG | 1 cut(s) | 10 |
| BcoDI | GTCTC | 3 cut(s) | 101, 329, 728 |
| BfaI | CTAG | 2 cut(s) | 273, 931 |
| BfmI | CTRYAG | 1 cut(s) | 547 |
| BfuI | GTATCC | 1 cut(s) | 847 |
| BisI | GCNGC | 1 cut(s) | 247 |
| BlsI | GCNGC | 1 cut(s) | 248 |
| Bme1390I | CCNGG | 1 cut(s) | 10 |
| BmgBI | CACGTC | 1 cut(s) | 717 |
| BmiI | GGNNCC | 3 cut(s) | 270, 399, 459 |
| BmrFI | CCNGG | 1 cut(s) | 10 |
| Bpu14I | TTCGAA | 1 cut(s) | 305 |
| BpuEI | CTTGAG | 2 cut(s) | 239, 447 |
| BpuMI | CCSGG | 1 cut(s) | 10 |
| BsaI | GGTCTC | 2 cut(s) | 329, 728 |
| BsaJI | CCNNGG | 3 cut(s) | 9, 339, 905 |
| BsaWI | WCCGGW | 1 cut(s) | 149 |
| Bsc4I | CCNNNNNNNGG | 1 cut(s) | 690 |
| Bse1I | ACTGG | 1 cut(s) | 757 |
| BseDI | CCNNGG | 3 cut(s) | 9, 339, 905 |
| BseGI | GGATG | 1 cut(s) | 10 |
| BseLI | CCNNNNNNNGG | 1 cut(s) | 690 |
| BseMII | CTCAG | 1 cut(s) | 324 |
| BseNI | ACTGG | 1 cut(s) | 757 |
| BseRI | GAGGAG | 1 cut(s) | 794 |
| BsgI | GTGCAG | 1 cut(s) | 393 |
| Bsh1236I | CGCG | 1 cut(s) | 740 |
| BshFI | GGCC | 2 cut(s) | 249, 852 |
| BshNI | GGYRCC | 2 cut(s) | 268, 457 |
| BsiSI | CCGG | 2 cut(s) | 9, 150 |
| BslFI | GGGAC | 1 cut(s) | 545 |
| BslI | CCNNNNNNNGG | 1 cut(s) | 690 |
| BsmAI | GTCTC | 3 cut(s) | 101, 329, 728 |
| BsmFI | GGGAC | 1 cut(s) | 545 |
| BsnI | GGCC | 2 cut(s) | 249, 852 |
| Bso31I | GGTCTC | 2 cut(s) | 329, 728 |
| Bsp119I | TTCGAA | 1 cut(s) | 305 |
| Bsp143I | GATC | 1 cut(s) | 55 |
| Bsp19I | CCATGG | 1 cut(s) | 905 |
| BspACI | CCGC | 3 cut(s) | 246, 581, 738 |
| BspANI | GGCC | 2 cut(s) | 249, 852 |
| BspCNI | CTCAG | 1 cut(s) | 325 |
| BspFNI | CGCG | 1 cut(s) | 740 |
| BspLI | GGNNCC | 3 cut(s) | 270, 399, 459 |
| BspT104I | TTCGAA | 1 cut(s) | 305 |
| BspT107I | GGYRCC | 2 cut(s) | 268, 457 |
| BspTNI | GGTCTC | 2 cut(s) | 329, 728 |
| BsrI | ACTGG | 1 cut(s) | 757 |
| BssECI | CCNNGG | 3 cut(s) | 9, 339, 905 |
| BssMI | GATC | 1 cut(s) | 55 |
| BssT1I | CCWWGG | 1 cut(s) | 905 |
| Bst4CI | ACNGT | 4 cut(s) | 112, 311, 340, 406 |
| Bst6I | CTCTTC | 2 cut(s) | 126, 435 |
| BstAPI | GCANNNNNTGC | 1 cut(s) | 800 |
| BstBI | TTCGAA | 1 cut(s) | 305 |
| BstC8I | GCNNGC | 3 cut(s) | 244, 251, 801 |
| BstDEI | CTNAG | 1 cut(s) | 333 |
| BstDSI | CCRYGG | 2 cut(s) | 339, 905 |
| BstF5I | GGATG | 1 cut(s) | 10 |
| BstFNI | CGCG | 1 cut(s) | 740 |
| BstHHI | GCGC | 1 cut(s) | 742 |
| BstKTI | GATC | 1 cut(s) | 58 |
| BstMAI | GTCTC | 3 cut(s) | 101, 329, 728 |
| BstMBI | GATC | 1 cut(s) | 55 |
| BstMWI | GCNNNNNNNGC | 2 cut(s) | 223, 800 |
| BstNSI | RCATGY | 2 cut(s) | 18, 882 |
| BstSCI | CCNGG | 1 cut(s) | 8 |
| BstSFI | CTRYAG | 1 cut(s) | 547 |
| BstUI | CGCG | 1 cut(s) | 740 |
| BsuI | GTATCC | 1 cut(s) | 847 |
| BsuRI | GGCC | 2 cut(s) | 249, 852 |
| BtgI | CCRYGG | 2 cut(s) | 339, 905 |
| BtrI | CACGTC | 1 cut(s) | 717 |
| BtsCI | GGATG | 1 cut(s) | 10 |
| Cac8I | GCNNGC | 3 cut(s) | 244, 251, 801 |
| CfoI | GCGC | 1 cut(s) | 742 |
| Csp6I | GTAC | 2 cut(s) | 269, 899 |
| CviAII | CATG | 7 cut(s) | 15, 671, 690, 758, 788, 879, 906 |
| CviJI | RGCY | 7 cut(s) | 217, 226, 249, 293, 658, 852, 893 |
| CviKI_1 | RGCY | 7 cut(s) | 217, 226, 249, 293, 658, 852, 893 |
| CviQI | GTAC | 2 cut(s) | 269, 899 |
| DdeI | CTNAG | 1 cut(s) | 333 |
| DpnI | GATC | 1 cut(s) | 57 |
| DpnII | GATC | 1 cut(s) | 55 |
| EaeI | YGGCCR | 1 cut(s) | 247 |
| Eam1104I | CTCTTC | 2 cut(s) | 126, 435 |
| EarI | CTCTTC | 2 cut(s) | 126, 435 |
| Eco130I | CCWWGG | 1 cut(s) | 905 |
| Eco31I | GGTCTC | 2 cut(s) | 329, 728 |
| Eco32I | GATATC | 2 cut(s) | 574, 808 |
| EcoRI | GAATTC | 1 cut(s) | 301 |
| EcoRV | GATATC | 2 cut(s) | 574, 808 |
| EcoT14I | CCWWGG | 1 cut(s) | 905 |
| ErhI | CCWWGG | 1 cut(s) | 905 |
| FaeI | CATG | 7 cut(s) | 18, 674, 693, 761, 791, 882, 909 |
| FalI | AAGNNNNNCTT | 4 cut(s) | 642, 674, 783, 815 |
| FaqI | GGGAC | 1 cut(s) | 545 |
| FatI | CATG | 7 cut(s) | 14, 670, 689, 757, 787, 878, 905 |
| FauNDI | CATATG | 1 cut(s) | 481 |
| FbaI | TGATCA | 1 cut(s) | 55 |
| FblI | GTMKAC | 1 cut(s) | 365 |
| Fnu4HI | GCNGC | 1 cut(s) | 247 |
| FokI | GGATG | 1 cut(s) | 17 |
| Fsp4HI | GCNGC | 1 cut(s) | 247 |
| FspBI | CTAG | 2 cut(s) | 273, 931 |
| GlaI | GCGC | 1 cut(s) | 741 |
| GluI | GCNGC | 1 cut(s) | 247 |
| HaeIII | GGCC | 2 cut(s) | 249, 852 |
| HapII | CCGG | 2 cut(s) | 9, 150 |
| HhaI | GCGC | 1 cut(s) | 742 |
| Hin1II | CATG | 7 cut(s) | 18, 674, 693, 761, 791, 882, 909 |
| Hin6I | GCGC | 1 cut(s) | 740 |
| HinP1I | GCGC | 1 cut(s) | 740 |
| HinfI | GANTC | 5 cut(s) | 125, 362, 443, 476, 922 |
| HpaII | CCGG | 2 cut(s) | 9, 150 |
| HphI | GGTGA | 3 cut(s) | 139, 570, 898 |
| Hpy166II | GTNNAC | 1 cut(s) | 366 |
| Hpy188I | TCNGA | 6 cut(s) | 130, 196, 334, 402, 571, 826 |
| Hpy188III | TCNNGA | 1 cut(s) | 106 |
| Hpy8I | GTNNAC | 1 cut(s) | 366 |
| Hpy99I | CGWCG | 1 cut(s) | 406 |
| HpyAV | CCTTC | 2 cut(s) | 206, 448 |
| HpyCH4III | ACNGT | 4 cut(s) | 112, 311, 340, 406 |
| HpyCH4IV | ACGT | 1 cut(s) | 716 |
| HpyCH4V | TGCA | 3 cut(s) | 25, 374, 864 |
| HpyF10VI | GCNNNNNNNGC | 2 cut(s) | 223, 800 |
| HpyF3I | CTNAG | 1 cut(s) | 333 |
| HpySE526I | ACGT | 1 cut(s) | 716 |
| Hsp92II | CATG | 7 cut(s) | 18, 674, 693, 761, 791, 882, 909 |
| HspAI | GCGC | 1 cut(s) | 740 |
| KpnI | GGTACC | 1 cut(s) | 272 |
| Ksp22I | TGATCA | 1 cut(s) | 55 |
| Kzo9I | GATC | 1 cut(s) | 55 |
| LmnI | GCTCC | 2 cut(s) | 66, 290 |
| LpnPI | CCDG | 7 cut(s) | 11, 22, 163, 263, 697, 738, 853 |
| MaeI | CTAG | 2 cut(s) | 273, 931 |
| MaeII | ACGT | 1 cut(s) | 716 |
| MaeIII | GTNAC | 1 cut(s) | 145 |
| MalI | GATC | 1 cut(s) | 57 |
| MboI | GATC | 1 cut(s) | 55 |
| MboII | GAAGA | 5 cut(s) | 143, 173, 402, 452, 463 |
| MluCI | AATT | 5 cut(s) | 301, 352, 413, 565, 627 |
| MlyI | GAGTC | 2 cut(s) | 371, 452 |
| MmeI | TCCRAC | 2 cut(s) | 358, 425 |
| MroXI | GAANNNNTTC | 1 cut(s) | 926 |
| MseI | TTAA | 3 cut(s) | 351, 434, 626 |
| MspI | CCGG | 2 cut(s) | 9, 150 |
| MspR9I | CCNGG | 1 cut(s) | 10 |
| MvnI | CGCG | 1 cut(s) | 740 |
| MwoI | GCNNNNNNNGC | 2 cut(s) | 223, 800 |
| NciI | CCSGG | 1 cut(s) | 10 |
| NcoI | CCATGG | 1 cut(s) | 905 |
| NdeI | CATATG | 1 cut(s) | 481 |
| NdeII | GATC | 1 cut(s) | 55 |
| NlaIII | CATG | 7 cut(s) | 18, 674, 693, 761, 791, 882, 909 |
| NlaIV | GGNNCC | 3 cut(s) | 270, 399, 459 |
| NmeAIII | GCCGAG | 1 cut(s) | 609 |
| NmuCI | GTSAC | 1 cut(s) | 145 |
| NspI | RCATGY | 2 cut(s) | 18, 882 |
| NspV | TTCGAA | 1 cut(s) | 305 |
| PdmI | GAANNNNTTC | 1 cut(s) | 926 |
| PfeI | GAWTC | 3 cut(s) | 125, 476, 922 |
| PkrI | GCNGC | 1 cut(s) | 248 |
| PleI | GAGTC | 2 cut(s) | 370, 451 |
| PpsI | GAGTC | 2 cut(s) | 370, 451 |
| PshBI | ATTAAT | 2 cut(s) | 351, 434 |
| PspN4I | GGNNCC | 3 cut(s) | 270, 399, 459 |
| RsaI | GTAC | 2 cut(s) | 270, 900 |
| RsaNI | GTAC | 2 cut(s) | 269, 899 |
| SaqAI | TTAA | 3 cut(s) | 351, 434, 626 |
| SatI | GCNGC | 1 cut(s) | 247 |
| Sau3AI | GATC | 1 cut(s) | 55 |
| SchI | GAGTC | 2 cut(s) | 371, 452 |
| ScrFI | CCNGG | 1 cut(s) | 10 |
| SfcI | CTRYAG | 1 cut(s) | 547 |
| SfuI | TTCGAA | 1 cut(s) | 305 |
| SmlI | CTYRAG | 2 cut(s) | 218, 462 |
| SmoI | CTYRAG | 2 cut(s) | 218, 462 |
| Sse9I | AATT | 5 cut(s) | 301, 352, 413, 565, 627 |
| SsiI | CCGC | 3 cut(s) | 246, 581, 738 |
| SspMI | CTAG | 2 cut(s) | 273, 931 |
| StyD4I | CCNGG | 1 cut(s) | 8 |
| StyI | CCWWGG | 1 cut(s) | 905 |
| TaaI | ACNGT | 4 cut(s) | 112, 311, 340, 406 |
| TaiI | ACGT | 1 cut(s) | 719 |
| TaqI | TCGA | 4 cut(s) | 77, 105, 305, 422 |
| TasI | AATT | 5 cut(s) | 301, 352, 413, 565, 627 |
| TatI | WGTACW | 1 cut(s) | 898 |
| TauI | GCSGC | 1 cut(s) | 249 |
| TfiI | GAWTC | 3 cut(s) | 125, 476, 922 |
| Tru1I | TTAA | 3 cut(s) | 351, 434, 626 |
| Tru9I | TTAA | 3 cut(s) | 351, 434, 626 |
| TseFI | GTSAC | 1 cut(s) | 145 |
| Tsp45I | GTSAC | 1 cut(s) | 145 |
| TspDTI | ATGAA | 5 cut(s) | 174, 468, 509, 804, 859 |
| VspI | ATTAAT | 2 cut(s) | 351, 434 |
| XapI | RAATTY | 2 cut(s) | 301, 565 |
| XceI | RCATGY | 2 cut(s) | 18, 882 |
| XmiI | GTMKAC | 1 cut(s) | 365 |
| XmnI | GAANNNNTTC | 1 cut(s) | 926 |
| XspI | CTAG | 2 cut(s) | 273, 931 |