MD02G1215900.v1.1

ER-associated misfolded protein catabolic process

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
malus_domestica
Chr02
OG0017190
Physical Location & Seq
Reverse (-)
24481732 .. 24482835
1104 bp
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UTR
Exon/CDS
Intron
MD02G1215900.v1.1.491

Sequence Viewer

Length: 1104 bp
ATGCGTGTTATCAAGAAATTTAAGGTTTTTCGCTTCACAAACCTCCCTGAAGAAGAAGAATCTCAACACTTTACTTCTTCTGGTTCTGAAATTAAGCGTTGCATCGGCACTCCTCAACATGATGACCCTTTTGAGTACGCTCATTCTCCTGATCATTCAGGTTATGTAACTTGCGAGCCCAGATGCTGTGAACTTGATGACGATGCTGTTTCAAATCTCCCAGAATCACAGGAAGGATATGAGCACCGCGAAACCTGTCAACTTGGTGATGATCATGGTGAAGATTACAAGCACGAAAGCAGTCAACTTGATGATAATGATGATATCCTCTTTCACTCTGGTGATGATTTAGAGGATGCTGACTGTCAACCTGAAAACCATGTAACTTGCGAGCCCGAAAGCTGTGAGCTAGATGACGATGCTGCTTCAAATCTCCCAGAATCACAAGAAGGATATGAGCACCACAAAATCTGTCAACTCGGTTATGATCATGATGAAGATTACGAGTGCGAAAGCAGTCAACTTGATGATATCGTCTGTCACTCTGATGATGATTTAGAGGATGCTGACTGTCAACCTGAATACCATGAAGTAGTTCGTACAGAACCAGAAGACGATTATGAAAAACCTTATTCTCCAGAACCGGAAGAAAAATCTGCCGACTTTTATGGTTCTCAAGTCAAGCCTTTCTCAAGTCCTTGTAATGATGATGATGATGATGATACCTCTGATGCTGCTGTTGATTCAACCTGCGATTCAACTTCTTCTCATGAAAGTGAACTTGAATGCGAGACTTGTACCCAACATAGCCATGATTATGGAAGCCTTCAACTTGACGATGGAGATGATTCATTCTGCCCTGTGAATAGTCCAGAGCCATTGTCTCCCCCAAGACCTGAAGAGTATTTCGACTGCAAGTTGTGTGTGAAGATGGCAAGGGAGCCAGTGGTGACTCCATGTGGTCATTTGTTTTGCGGGGATTGCTTGGACAAATGGCTGAACTTCTTCACTTCTGAGATGCAGTGCCCTGTTTGTAGGAGCAAGGTGTTTGGTTCCTCCATCATTCTGATCAGCCCGCCACCATGGTGGCAACTGAGACCTTGA
Functional Annotation
Gene Ontology
Molecular Function
Biological Process
Cellular Component
No ontology terms assigned.
KEGG Pathways
Metabolic & Signaling
ko04141 map04141
Pfam Domains
Protein Families
Prok-RING_4 zf-C3HC4 zf-C3HC4_3 zf-RING_5

Protein Analysis

368

Amino Acids

41.67

Weight (kDa)

4.12

Isoelectric Point (pI)

59.89

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
zf-C3HC4_3 PF13920 304 - 349 3.8e-10 Zinc finger, C3HC4 type (RING finger)
zf-RING_2 PF13639 304 - 346 2e-08 Ring finger domain
zf-C3HC4 PF00097 305 - 345 1.5e-10 Zinc finger, C3HC4 type (RING finger)
zf-C3HC4_2 PF13923 305 - 345 8.9e-09 Zinc finger, C3HC4 type (RING finger)
zf-RING_5 PF14634 305 - 346 7.3e-08 zinc-RING finger domain
Prok-RING_4 PF14447 305 - 349 5.3e-07 Prokaryotic RING finger family 4
zf-RING_UBOX PF13445 305 - 343 1.4e-06 RING-type zinc-finger
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
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Publication-ready
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Orthologous Genes (Group: OG0017190)

Species Orthologous Gene IDs
arabidopsis_thaliana AT1G74990
fragaria_vesca FvH4_4g34391
malus_domestica MD02G1215900.v1.1
prunus_persica Prupe.8G036400_v2.0.a1
pyrus_communis pycom07g09040
rosa_chinensis RchiOBHm_Chr4g0443821
rosa_laevigata RLG00000005885
rosa_roxburghii Rroxscaffold_5G00384390
rosa_rugosa Rorug04G0347600
rosa_samantha Rh4AG407800 Rh4BG418800 Rh4CG432900 Rh4DG414000

Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
Acc36I ACCTGC 1 cut(s) 758
AccII CGCG 1 cut(s) 249
AciI CCGC 3 cut(s) 247, 975, 1076
AcsI RAATTY 1 cut(s) 17
AcuI CTGAAG 2 cut(s) 69, 918
AfaI GTAC 3 cut(s) 137, 601, 799
AgsI TTSAA 6 cut(s) 213, 429, 747, 759, 785, 830
AleI CACNNNNGTG 2 cut(s) 339, 1084
AluBI AGCT 2 cut(s) 402, 409
AluI AGCT 2 cut(s) 402, 409
Alw21I GWGCWC 2 cut(s) 246, 462
Alw26I GTCTC 3 cut(s) 785, 888, 1090
AlwNI CAGNNNCTG 1 cut(s) 186
ApeKI GCWGC 2 cut(s) 422, 734
ApoI RAATTY 1 cut(s) 17
Asp700I GAANNNNTTC 2 cut(s) 594, 1004
AsuHPI GGTGA 4 cut(s) 278, 290, 353, 961
BaeGI GKGCMC 1 cut(s) 1028
BanII GRGCYC 2 cut(s) 180, 396
BbsI GAAGAC 1 cut(s) 618
Bbv12I GWGCWC 2 cut(s) 246, 462
BbvI GCAGC 2 cut(s) 409, 721
BccI CCATC 3 cut(s) 833, 925, 1067
BclI TGATCA 4 cut(s) 151, 271, 487, 1068
BcoDI GTCTC 3 cut(s) 785, 888, 1090
BfaI CTAG 1 cut(s) 410
BfuAI ACCTGC 1 cut(s) 758
BisI GCNGC 2 cut(s) 423, 735
BlsI GCNGC 2 cut(s) 424, 736
BmiI GGNNCC 2 cut(s) 942, 1054
BmsI GCATC 8 cut(s) 111, 173, 193, 346, 409, 553, 721, 1008
BpiI GAAGAC 1 cut(s) 618
BpmI CTGGAG 1 cut(s) 621
BpuEI CTTGAG 2 cut(s) 660, 676
BsaI GGTCTC 1 cut(s) 1090
BsaJI CCNNGG 1 cut(s) 1082
BsaWI WCCGGW 1 cut(s) 643
Bse1I ACTGG 1 cut(s) 944
BseDI CCNNGG 1 cut(s) 1082
BseGI GGATG 2 cut(s) 361, 568
BseMII CTCAG 2 cut(s) 1005, 1085
BseNI ACTGG 1 cut(s) 944
BseRI GAGGAG 1 cut(s) 102
BseSI GKGCMC 1 cut(s) 1028
BseXI GCAGC 2 cut(s) 409, 721
Bsh1236I CGCG 1 cut(s) 249
BsiHKAI GWGCWC 2 cut(s) 246, 462
BsiSI CCGG 1 cut(s) 644
BsmAI GTCTC 3 cut(s) 785, 888, 1090
BsmI GAATGC 1 cut(s) 791
Bso31I GGTCTC 1 cut(s) 1090
Bsp1286I GDGCHC 5 cut(s) 180, 246, 396, 462, 1028
Bsp143I GATC 4 cut(s) 151, 271, 487, 1068
Bsp19I CCATGG 1 cut(s) 1082
BspACI CCGC 3 cut(s) 247, 975, 1076
BspCNI CTCAG 2 cut(s) 1006, 1086
BspFNI CGCG 1 cut(s) 249
BspHI TCATGA 2 cut(s) 490, 769
BspLI GGNNCC 2 cut(s) 942, 1054
BspMI ACCTGC 1 cut(s) 758
BspTNI GGTCTC 1 cut(s) 1090
BsrI ACTGG 1 cut(s) 944
BssECI CCNNGG 1 cut(s) 1082
BssMI GATC 4 cut(s) 151, 271, 487, 1068
BssT1I CCWWGG 1 cut(s) 1082
Bst4CI ACNGT 2 cut(s) 365, 572
Bst6I CTCTTC 1 cut(s) 894
BstC8I GCNNGC 3 cut(s) 176, 392, 1076
BstDEI CTNAG 2 cut(s) 1014, 1094
BstDSI CCRYGG 1 cut(s) 1082
BstF5I GGATG 2 cut(s) 361, 568
BstFNI CGCG 1 cut(s) 249
BstKTI GATC 4 cut(s) 154, 274, 490, 1071
BstMAI GTCTC 3 cut(s) 785, 888, 1090
BstMBI GATC 4 cut(s) 151, 271, 487, 1068
BstMWI GCNNNNNNNGC 1 cut(s) 981
BstSLI GKGCMC 1 cut(s) 1028
BstUI CGCG 1 cut(s) 249
BstV1I GCAGC 2 cut(s) 409, 721
BstV2I GAAGAC 1 cut(s) 618
BstXI CCANNNNNNTGG 2 cut(s) 818, 1086
BtgI CCRYGG 1 cut(s) 1082
BtsCI GGATG 2 cut(s) 361, 568
BtsI GCAGTG 1 cut(s) 1028
BtsIMutI CAGTG 2 cut(s) 951, 1028
BveI ACCTGC 1 cut(s) 758
Cac8I GCNNGC 3 cut(s) 176, 392, 1076
CaiI CAGNNNCTG 1 cut(s) 186
CciI TCATGA 2 cut(s) 490, 769
Csp6I GTAC 3 cut(s) 136, 600, 798
CviAII CATG 9 cut(s) 119, 275, 380, 491, 587, 770, 812, 957, 1083
CviQI GTAC 3 cut(s) 136, 600, 798
DdeI CTNAG 2 cut(s) 1014, 1094
DpnI GATC 4 cut(s) 153, 273, 489, 1070
DpnII GATC 4 cut(s) 151, 271, 487, 1068
Eam1104I CTCTTC 1 cut(s) 894
EarI CTCTTC 1 cut(s) 894
Eco130I CCWWGG 1 cut(s) 1082
Eco24I GRGCYC 2 cut(s) 180, 396
Eco31I GGTCTC 1 cut(s) 1090
Eco32I GATATC 2 cut(s) 325, 532
Eco57I CTGAAG 2 cut(s) 69, 918
EcoRV GATATC 2 cut(s) 325, 532
EcoT14I CCWWGG 1 cut(s) 1082
EcoT38I GRGCYC 2 cut(s) 180, 396
ErhI CCWWGG 1 cut(s) 1082
FaeI CATG 9 cut(s) 122, 278, 383, 494, 590, 773, 815, 960, 1086
FatI CATG 9 cut(s) 118, 274, 379, 490, 586, 769, 811, 956, 1082
FauI CCCGC 2 cut(s) 968, 1083
FbaI TGATCA 4 cut(s) 151, 271, 487, 1068
Fnu4HI GCNGC 2 cut(s) 423, 735
FokI GGATG 2 cut(s) 368, 575
FriOI GRGCYC 2 cut(s) 180, 396
Fsp4HI GCNGC 2 cut(s) 423, 735
FspBI CTAG 1 cut(s) 410
GluI GCNGC 2 cut(s) 423, 735
GsuI CTGGAG 1 cut(s) 621
HapII CCGG 1 cut(s) 644
Hin1II CATG 9 cut(s) 122, 278, 383, 494, 590, 773, 815, 960, 1086
HincII GTYRAC 6 cut(s) 260, 305, 368, 476, 521, 575
HindII GTYRAC 6 cut(s) 260, 305, 368, 476, 521, 575
HinfI GANTC 7 cut(s) 59, 224, 440, 743, 755, 848, 952
HpaII CCGG 1 cut(s) 644
HphI GGTGA 4 cut(s) 278, 290, 353, 961
Hpy166II GTNNAC 8 cut(s) 191, 260, 305, 368, 476, 521, 575, 779
Hpy188I TCNGA 5 cut(s) 88, 547, 730, 1015, 1068
Hpy188III TCNNGA 6 cut(s) 13, 149, 491, 638, 770, 872
Hpy8I GTNNAC 8 cut(s) 191, 260, 305, 368, 476, 521, 575, 779
HpyAV CCTTC 3 cut(s) 227, 443, 836
HpyCH4III ACNGT 2 cut(s) 365, 572
HpyCH4V TGCA 3 cut(s) 102, 915, 1021
HpyF10VI GCNNNNNNNGC 1 cut(s) 981
HpyF3I CTNAG 2 cut(s) 1014, 1094
Hsp92II CATG 9 cut(s) 122, 278, 383, 494, 590, 773, 815, 960, 1086
Ksp22I TGATCA 4 cut(s) 151, 271, 487, 1068
Kzo9I GATC 4 cut(s) 151, 271, 487, 1068
LmnI GCTCC 2 cut(s) 940, 1038
Lsp1109I GCAGC 2 cut(s) 409, 721
LweI GCATC 8 cut(s) 111, 173, 193, 346, 409, 553, 721, 1008
MaeI CTAG 1 cut(s) 410
MaeIII GTNAC 4 cut(s) 166, 382, 539, 949
MalI GATC 4 cut(s) 153, 273, 489, 1070
MboI GATC 4 cut(s) 151, 271, 487, 1068
MhlI GDGCHC 5 cut(s) 180, 246, 396, 462, 1028
MluCI AATT 2 cut(s) 17, 90
MlyI GAGTC 1 cut(s) 946
MnlI CCTC 7 cut(s) 53, 123, 338, 346, 553, 736, 1066
MroXI GAANNNNTTC 2 cut(s) 594, 1004
MseI TTAA 2 cut(s) 21, 93
MslI CAYNNNNRTG 6 cut(s) 339, 546, 774, 810, 816, 1084
MspI CCGG 1 cut(s) 644
Mva1269I GAATGC 1 cut(s) 791
MvnI CGCG 1 cut(s) 249
MwoI GCNNNNNNNGC 1 cut(s) 981
NcoI CCATGG 1 cut(s) 1082
NdeII GATC 4 cut(s) 151, 271, 487, 1068
NlaIII CATG 9 cut(s) 122, 278, 383, 494, 590, 773, 815, 960, 1086
NlaIV GGNNCC 2 cut(s) 942, 1054
NmuCI GTSAC 2 cut(s) 539, 949
OliI CACNNNNGTG 2 cut(s) 339, 1084
PagI TCATGA 2 cut(s) 490, 769
PctI GAATGC 1 cut(s) 791
PdmI GAANNNNTTC 2 cut(s) 594, 1004
PfeI GAWTC 6 cut(s) 59, 224, 440, 743, 755, 848
PkrI GCNGC 2 cut(s) 424, 736
PleI GAGTC 1 cut(s) 946
PpsI GAGTC 1 cut(s) 946
PspN4I GGNNCC 2 cut(s) 942, 1054
PstNI CAGNNNCTG 1 cut(s) 186
RsaI GTAC 3 cut(s) 137, 601, 799
RsaNI GTAC 3 cut(s) 136, 600, 798
RseI CAYNNNNRTG 6 cut(s) 339, 546, 774, 810, 816, 1084
SaqAI TTAA 2 cut(s) 21, 93
SatI GCNGC 2 cut(s) 423, 735
Sau3AI GATC 4 cut(s) 151, 271, 487, 1068
SchI GAGTC 1 cut(s) 946
SduI GDGCHC 5 cut(s) 180, 246, 396, 462, 1028
SfaNI GCATC 8 cut(s) 111, 173, 193, 346, 409, 553, 721, 1008
SmiMI CAYNNNNRTG 6 cut(s) 339, 546, 774, 810, 816, 1084
SmlI CTYRAG 2 cut(s) 675, 691
SmoI CTYRAG 2 cut(s) 675, 691
Sse9I AATT 2 cut(s) 17, 90
SsiI CCGC 3 cut(s) 247, 975, 1076
SspMI CTAG 1 cut(s) 410
StyI CCWWGG 1 cut(s) 1082
TaaI ACNGT 2 cut(s) 365, 572
TaqI TCGA 1 cut(s) 909
TasI AATT 2 cut(s) 17, 90
TfiI GAWTC 6 cut(s) 59, 224, 440, 743, 755, 848
Tru1I TTAA 2 cut(s) 21, 93
Tru9I TTAA 2 cut(s) 21, 93
TscAI CASTG 2 cut(s) 951, 1028
TseFI GTSAC 2 cut(s) 539, 949
TseI GCWGC 2 cut(s) 422, 734
Tsp45I GTSAC 2 cut(s) 539, 949
TspDTI ATGAA 5 cut(s) 510, 603, 636, 786, 840
TspRI CASTG 2 cut(s) 951, 1028
XapI RAATTY 1 cut(s) 17
XmnI GAANNNNTTC 2 cut(s) 594, 1004
XspI CTAG 1 cut(s) 410
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.