MD02G1262600.v1.1

Presenilin enhancer-2 subunit of gamma secretase

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
malus_domestica
Chr02
OG0010505
Physical Location & Seq
Forward (+)
31710168 .. 31711974
1807 bp
Loading structure...
UTR
Exon/CDS
Intron
MD02G1262600.v1.1.491

Sequence Viewer

Length: 324 bp
ATGGAAGCTTCACGGAGTAACTCGGAAATTCCGAACCTGAACCCTAGCCCGAGAAGAAACCCGATTCCGATTCCGTCTGCATCGCTGAGGTGGCCCACCATAGACGGCCCACTAGGTCTGTCAGAGGAAGAGTCAGTGAGCTACGCGCGTAGATTCTACAAGTTCGGCTTCGCTCTGCTCCCTTGGCTTTGGGCTCTCAACTGCTTCTACTTCTGGCCCGTCCTCCGCCACTCCCGCTCCTTCCCTCGCATTCACCACTTTAAAAAGGGGGAAAGATGTTTTCTCCCTCCTAGGAATGTCAGAGGTGATTACAACTTGAATTAA

Protein Analysis

108

Amino Acids

12.59

Weight (kDa)

10.12

Isoelectric Point (pI)

78.24

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
PEN-2 PF10251 42 - 87 1e-13 Presenilin enhancer-2 subunit of gamma secretase
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
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Orthologous Genes (Group: OG0010505)

Species Orthologous Gene IDs
arabidopsis_thaliana AT5G09310
fragaria_vesca FvH4_2g08820 FvH4_2g08820 FvH4_2g08820 FvH4_2g08820 FvH4_2g08820 FvH4_3g04510
malus_domestica MD02G1262600.v1.1 MD07G1057500.v1.1
prunus_persica Prupe.4G271100_v2.0.a1
pyrus_communis pycom02g22520
rosa_chinensis RchiOBHm_Chr6g0264391
rosa_laevigata RLG00000014257
rosa_multiflora Rmu_sc0004470.1_g000020
rosa_roxburghii Rroxscaffold_176G00431770
rosa_rugosa Rorug06G0012000 Rorug06G0012100
rosa_samantha Rh6BG129000 Rh6CG127000 Rh6DG114500
rosa_wichuraiana Rw6G011520

Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AccBSI CCGCTC 1 cut(s) 237
AccII CGCG 2 cut(s) 146, 148
AciI CCGC 2 cut(s) 226, 235
AcsI RAATTY 1 cut(s) 27
AgsI TTSAA 1 cut(s) 319
AluBI AGCT 2 cut(s) 8, 141
AluI AGCT 2 cut(s) 8, 141
Ama87I CYCGRG 1 cut(s) 49
AoxI GGCC 3 cut(s) 92, 106, 215
ApoI RAATTY 1 cut(s) 27
AspA2I CCTAGG 1 cut(s) 290
AspLEI GCGC 1 cut(s) 148
AspS9I GGNCC 3 cut(s) 93, 107, 216
AsuHPI GGTGA 2 cut(s) 245, 317
AvaI CYCGRG 1 cut(s) 49
AvrII CCTAGG 1 cut(s) 290
BanII GRGCYC 1 cut(s) 196
BbvCI CCTCAGC 1 cut(s) 86
BceAI ACGGC 1 cut(s) 121
BfaI CTAG 3 cut(s) 45, 113, 291
BlnI CCTAGG 1 cut(s) 290
BmeT110I CYCGRG 1 cut(s) 49
BmgT120I GGNCC 3 cut(s) 93, 107, 216
BmsI GCATC 1 cut(s) 89
Bpu10I CCTNAGC 1 cut(s) 86
BsaJI CCNNGG 2 cut(s) 182, 290
BsaXI ACNNNNNCTCC 2 cut(s) 221, 251
BseDI CCNNGG 2 cut(s) 182, 290
BseMII CTCAG 1 cut(s) 77
Bsh1236I CGCG 2 cut(s) 146, 148
BshFI GGCC 3 cut(s) 94, 108, 217
BsiHKCI CYCGRG 1 cut(s) 49
BsmI GAATGC 1 cut(s) 249
BsnI GGCC 3 cut(s) 94, 108, 217
BsoBI CYCGRG 1 cut(s) 49
Bsp1286I GDGCHC 1 cut(s) 196
BspACI CCGC 2 cut(s) 226, 235
BspANI GGCC 3 cut(s) 94, 108, 217
BspCNI CTCAG 1 cut(s) 78
BspFNI CGCG 2 cut(s) 146, 148
BsrBI CCGCTC 1 cut(s) 237
BssECI CCNNGG 2 cut(s) 182, 290
BssT1I CCWWGG 2 cut(s) 182, 290
Bst6I CTCTTC 1 cut(s) 123
BstDEI CTNAG 1 cut(s) 86
BstFNI CGCG 2 cut(s) 146, 148
BstHHI GCGC 1 cut(s) 148
BstMWI GCNNNNNNNGC 3 cut(s) 91, 184, 234
BstUI CGCG 2 cut(s) 146, 148
BsuRI GGCC 3 cut(s) 94, 108, 217
BtgZI GCGATG 1 cut(s) 66
BtsIMutI CAGTG 1 cut(s) 141
CfoI GCGC 1 cut(s) 148
Cfr13I GGNCC 3 cut(s) 93, 107, 216
CviJI RGCY 9 cut(s) 8, 48, 94, 108, 141, 168, 187, 194, 217
CviKI_1 RGCY 9 cut(s) 8, 48, 94, 108, 141, 168, 187, 194, 217
DdeI CTNAG 1 cut(s) 86
DraI TTTAAA 1 cut(s) 262
Eam1104I CTCTTC 1 cut(s) 123
EarI CTCTTC 1 cut(s) 123
EciI GGCGGA 1 cut(s) 215
Eco130I CCWWGG 2 cut(s) 182, 290
Eco24I GRGCYC 1 cut(s) 196
Eco88I CYCGRG 1 cut(s) 49
EcoT14I CCWWGG 2 cut(s) 182, 290
EcoT38I GRGCYC 1 cut(s) 196
ErhI CCWWGG 2 cut(s) 182, 290
FaiI YATR 1 cut(s) 101
FalI AAGNNNNNCTT 2 cut(s) 152, 184
FauI CCCGC 1 cut(s) 242
FriOI GRGCYC 1 cut(s) 196
FspBI CTAG 3 cut(s) 45, 113, 291
GlaI GCGC 1 cut(s) 147
HaeIII GGCC 3 cut(s) 94, 108, 217
HhaI GCGC 1 cut(s) 148
Hin6I GCGC 1 cut(s) 146
HinP1I GCGC 1 cut(s) 146
HindIII AAGCTT 1 cut(s) 6
HinfI GANTC 4 cut(s) 64, 70, 131, 153
HphI GGTGA 2 cut(s) 245, 317
Hpy188I TCNGA 5 cut(s) 25, 33, 69, 124, 302
HpyAV CCTTC 1 cut(s) 250
HpyCH4V TGCA 1 cut(s) 80
HpyF10VI GCNNNNNNNGC 3 cut(s) 91, 184, 234
HpyF3I CTNAG 1 cut(s) 86
HspAI GCGC 1 cut(s) 146
LmnI GCTCC 2 cut(s) 183, 242
LpnPI CCDG 2 cut(s) 50, 199
LweI GCATC 1 cut(s) 89
MaeI CTAG 3 cut(s) 45, 113, 291
MaeIII GTNAC 1 cut(s) 17
MbiI CCGCTC 1 cut(s) 237
MboII GAAGA 2 cut(s) 66, 140
MhlI GDGCHC 1 cut(s) 196
MluCI AATT 2 cut(s) 27, 319
MlyI GAGTC 1 cut(s) 140
MnlI CCTC 6 cut(s) 81, 118, 233, 255, 296, 297
MseI TTAA 2 cut(s) 261, 322
Mva1269I GAATGC 1 cut(s) 249
MvnI CGCG 2 cut(s) 146, 148
MwoI GCNNNNNNNGC 3 cut(s) 91, 184, 234
PcsI WCGNNNNNNNCGW 1 cut(s) 29
PctI GAATGC 1 cut(s) 249
PfeI GAWTC 3 cut(s) 64, 70, 153
PleI GAGTC 1 cut(s) 139
PpsI GAGTC 1 cut(s) 139
PspPI GGNCC 3 cut(s) 93, 107, 216
SaqAI TTAA 2 cut(s) 261, 322
Sau96I GGNCC 3 cut(s) 93, 107, 216
SchI GAGTC 1 cut(s) 140
SduI GDGCHC 1 cut(s) 196
SetI ASST 6 cut(s) 10, 39, 92, 118, 143, 307
SfaNI GCATC 1 cut(s) 89
Sse9I AATT 2 cut(s) 27, 319
SsiI CCGC 2 cut(s) 226, 235
SspMI CTAG 3 cut(s) 45, 113, 291
StyI CCWWGG 2 cut(s) 182, 290
TasI AATT 2 cut(s) 27, 319
TfiI GAWTC 3 cut(s) 64, 70, 153
Tru1I TTAA 2 cut(s) 261, 322
Tru9I TTAA 2 cut(s) 261, 322
TscAI CASTG 1 cut(s) 141
TspGWI ACGGA 2 cut(s) 28, 63
TspRI CASTG 1 cut(s) 141
XapI RAATTY 1 cut(s) 27
XmaJI CCTAGG 1 cut(s) 290
XspI CTAG 3 cut(s) 45, 113, 291
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.