The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins. Some of these proteins have been shown both in vivo and in vitro to have ubiquitin E3 ligase activity.
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| Species | Orthologous Gene IDs |
|---|---|
| fragaria_vesca | FvH4_6g15720 FvH4_6g15720 FvH4_6g15720 FvH4_6g15720 FvH4_6g15720 FvH4_6g15720 FvH4_6g15720 FvH4_6g15720 |
| malus_domestica | MD04G1099800.v1.1 MD12G1119900.v1.1 |
| prunus_persica | Prupe.6G238100_v2.0.a1 Prupe.6G238100_v2.0.a1 |
| pyrus_communis | pycom04g09490 pycom12g11880 |
| rosa_chinensis | RchiOBHm_Chr3g0469421 |
| rosa_laevigata | RLG00000024350 |
| rosa_multiflora | Rmu_sc0005274.1_g000008 |
| rosa_roxburghii | Rroxscaffold_6G00411900 |
| rosa_rugosa | Rorug03G0101700 Rorug03G0101700 |
| rosa_samantha | Rh3AG150700 Rh3BG174400 Rh3CG165400 Rh3DG201000 |
| rosa_wichuraiana | Rw3G014210 |
| Enzyme | Recognition Site | Cut Count | Positions (bp) |
|---|---|---|---|
| Acc36I | ACCTGC | 1 cut(s) | 424 |
| AciI | CCGC | 2 cut(s) | 93, 762 |
| AclWI | GGATC | 1 cut(s) | 1138 |
| AcsI | RAATTY | 4 cut(s) | 798, 975, 1217, 1357 |
| AcuI | CTGAAG | 2 cut(s) | 48, 357 |
| AcvI | CACGTG | 1 cut(s) | 428 |
| AcyI | GRCGYC | 1 cut(s) | 90 |
| AfiI | CCNNNNNNNGG | 1 cut(s) | 841 |
| AflIII | ACRYGT | 3 cut(s) | 425, 923, 1270 |
| AgsI | TTSAA | 9 cut(s) | 72, 107, 165, 355, 447, 720, 812, 980, 1499 |
| AjnI | CCWGG | 3 cut(s) | 118, 292, 402 |
| AjuI | GAANNNNNNNTTGG | 2 cut(s) | 585, 617 |
| AleI | CACNNNNGTG | 1 cut(s) | 1205 |
| Alw21I | GWGCWC | 2 cut(s) | 1018, 1278 |
| Alw26I | GTCTC | 4 cut(s) | 81, 127, 230, 1153 |
| AlwI | GGATC | 1 cut(s) | 1138 |
| AlwNI | CAGNNNCTG | 3 cut(s) | 623, 737, 1114 |
| Ama87I | CYCGRG | 1 cut(s) | 1002 |
| AoxI | GGCC | 2 cut(s) | 64, 588 |
| ApeKI | GCWGC | 4 cut(s) | 389, 1108, 1441, 1533 |
| ApoI | RAATTY | 4 cut(s) | 798, 975, 1217, 1357 |
| ArsI | GACNNNNNNTTYG | 2 cut(s) | 521, 553 |
| AseI | ATTAAT | 1 cut(s) | 630 |
| Asp700I | GAANNNNTTC | 1 cut(s) | 1524 |
| AspLEI | GCGC | 1 cut(s) | 1477 |
| AspS9I | GGNCC | 4 cut(s) | 65, 296, 456, 589 |
| AsuHPI | GGTGA | 6 cut(s) | 776, 830, 872, 1219, 1446, 1447 |
| AsuNHI | GCTAGC | 1 cut(s) | 1084 |
| AvaI | CYCGRG | 1 cut(s) | 1002 |
| AvaII | GGWCC | 2 cut(s) | 296, 456 |
| BbrPI | CACGTG | 1 cut(s) | 428 |
| Bbv12I | GWGCWC | 2 cut(s) | 1018, 1278 |
| BbvI | GCAGC | 3 cut(s) | 376, 1120, 1453 |
| BccI | CCATC | 8 cut(s) | 32, 632, 740, 752, 835, 1070, 1377, 1389 |
| BciT130I | CCWGG | 3 cut(s) | 120, 294, 404 |
| BcoDI | GTCTC | 4 cut(s) | 81, 127, 230, 1153 |
| BfaI | CTAG | 5 cut(s) | 267, 398, 480, 815, 1085 |
| BfmI | CTRYAG | 2 cut(s) | 417, 777 |
| BfuAI | ACCTGC | 1 cut(s) | 424 |
| BisI | GCNGC | 5 cut(s) | 93, 390, 1109, 1442, 1534 |
| BlsI | GCNGC | 5 cut(s) | 94, 391, 1110, 1443, 1535 |
| Bme1390I | CCNGG | 3 cut(s) | 120, 294, 404 |
| Bme18I | GGWCC | 2 cut(s) | 296, 456 |
| BmeT110I | CYCGRG | 1 cut(s) | 1002 |
| BmgT120I | GGNCC | 4 cut(s) | 65, 296, 456, 589 |
| BmiI | GGNNCC | 1 cut(s) | 298 |
| BmrFI | CCNGG | 3 cut(s) | 120, 294, 404 |
| BmrI | ACTGGG | 1 cut(s) | 725 |
| BmsI | GCATC | 3 cut(s) | 169, 503, 1193 |
| BmtI | GCTAGC | 1 cut(s) | 1088 |
| BmuI | ACTGGG | 1 cut(s) | 725 |
| BplI | GAGNNNNNCTC | 2 cut(s) | 214, 246 |
| BpmI | CTGGAG | 1 cut(s) | 30 |
| BpuEI | CTTGAG | 4 cut(s) | 194, 821, 1124, 1494 |
| BsaAI | YACGTR | 1 cut(s) | 428 |
| BsaHI | GRCGYC | 1 cut(s) | 90 |
| BsaJI | CCNNGG | 3 cut(s) | 128, 402, 403 |
| Bsc4I | CCNNNNNNNGG | 1 cut(s) | 841 |
| Bse1I | ACTGG | 3 cut(s) | 13, 731, 1257 |
| Bse3DI | GCAATG | 1 cut(s) | 1283 |
| BseBI | CCWGG | 3 cut(s) | 120, 294, 404 |
| BseDI | CCNNGG | 3 cut(s) | 128, 402, 403 |
| BseGI | GGATG | 6 cut(s) | 184, 497, 725, 1060, 1062, 1184 |
| BseLI | CCNNNNNNNGG | 1 cut(s) | 841 |
| BseMI | GCAATG | 1 cut(s) | 1283 |
| BseMII | CTCAG | 9 cut(s) | 87, 361, 583, 687, 1017, 1049, 1256, 1278, 1442 |
| BseNI | ACTGG | 3 cut(s) | 13, 731, 1257 |
| BseRI | GAGGAG | 1 cut(s) | 105 |
| BseXI | GCAGC | 3 cut(s) | 376, 1120, 1453 |
| BseYI | CCCAGC | 1 cut(s) | 260 |
| BsgI | GTGCAG | 1 cut(s) | 868 |
| BshFI | GGCC | 2 cut(s) | 66, 590 |
| BsiHKAI | GWGCWC | 2 cut(s) | 1018, 1278 |
| BsiHKCI | CYCGRG | 1 cut(s) | 1002 |
| BslFI | GGGAC | 3 cut(s) | 282, 436, 605 |
| BslI | CCNNNNNNNGG | 1 cut(s) | 841 |
| BsmAI | GTCTC | 4 cut(s) | 81, 127, 230, 1153 |
| BsmBI | CGTCTC | 2 cut(s) | 81, 127 |
| BsmFI | GGGAC | 3 cut(s) | 282, 436, 605 |
| BsmI | GAATGC | 2 cut(s) | 696, 1468 |
| BsnI | GGCC | 2 cut(s) | 66, 590 |
| BsoBI | CYCGRG | 1 cut(s) | 1002 |
| Bsp1286I | GDGCHC | 2 cut(s) | 1018, 1278 |
| Bsp143I | GATC | 1 cut(s) | 1130 |
| Bsp19I | CCATGG | 1 cut(s) | 128 |
| BspACI | CCGC | 2 cut(s) | 93, 762 |
| BspANI | GGCC | 2 cut(s) | 66, 590 |
| BspCNI | CTCAG | 9 cut(s) | 88, 360, 582, 688, 1018, 1048, 1255, 1277, 1441 |
| BspLI | GGNNCC | 1 cut(s) | 298 |
| BspMAI | CTGCAG | 1 cut(s) | 421 |
| BspMI | ACCTGC | 1 cut(s) | 424 |
| BspOI | GCTAGC | 1 cut(s) | 1088 |
| BspPI | GGATC | 1 cut(s) | 1138 |
| BsrDI | GCAATG | 1 cut(s) | 1283 |
| BsrI | ACTGG | 3 cut(s) | 13, 731, 1257 |
| BssECI | CCNNGG | 3 cut(s) | 128, 402, 403 |
| BssMI | GATC | 1 cut(s) | 1130 |
| BssNI | GRCGYC | 1 cut(s) | 90 |
| BssT1I | CCWWGG | 1 cut(s) | 128 |
| Bst2UI | CCWGG | 3 cut(s) | 120, 294, 404 |
| Bst4CI | ACNGT | 1 cut(s) | 22 |
| Bst6I | CTCTTC | 1 cut(s) | 1158 |
| BstACI | GRCGYC | 1 cut(s) | 90 |
| BstBAI | YACGTR | 1 cut(s) | 428 |
| BstC8I | GCNNGC | 5 cut(s) | 64, 938, 1082, 1086, 1299 |
| BstDSI | CCRYGG | 1 cut(s) | 128 |
| BstEII | GGTNACC | 1 cut(s) | 860 |
| BstF5I | GGATG | 6 cut(s) | 184, 497, 725, 1060, 1062, 1184 |
| BstHHI | GCGC | 1 cut(s) | 1477 |
| BstKTI | GATC | 1 cut(s) | 1133 |
| BstMAI | GTCTC | 4 cut(s) | 81, 127, 230, 1153 |
| BstMBI | GATC | 1 cut(s) | 1130 |
| BstMWI | GCNNNNNNNGC | 4 cut(s) | 217, 398, 1294, 1472 |
| BstNI | CCWGG | 3 cut(s) | 120, 294, 404 |
| BstNSI | RCATGY | 6 cut(s) | 211, 927, 1084, 1274, 1297, 1301 |
| BstPI | GGTNACC | 1 cut(s) | 860 |
| BstSCI | CCNGG | 3 cut(s) | 118, 292, 402 |
| BstSFI | CTRYAG | 2 cut(s) | 417, 777 |
| BstV1I | GCAGC | 3 cut(s) | 376, 1120, 1453 |
| BstXI | CCANNNNNNTGG | 2 cut(s) | 83, 1330 |
| BsuRI | GGCC | 2 cut(s) | 66, 590 |
| BtgI | CCRYGG | 1 cut(s) | 128 |
| BtsCI | GGATG | 6 cut(s) | 184, 497, 725, 1060, 1062, 1184 |
| BtsIMutI | CAGTG | 3 cut(s) | 289, 741, 1250 |
| BveI | ACCTGC | 1 cut(s) | 424 |
| Cac8I | GCNNGC | 5 cut(s) | 64, 938, 1082, 1086, 1299 |
| CaiI | CAGNNNCTG | 3 cut(s) | 623, 737, 1114 |
| CfoI | GCGC | 1 cut(s) | 1477 |
| Cfr13I | GGNCC | 4 cut(s) | 65, 296, 456, 589 |
| CseI | GACGC | 2 cut(s) | 98, 1447 |
| CspCI | CAANNNNNGTGG | 2 cut(s) | 265, 300 |
| DpnI | GATC | 1 cut(s) | 1132 |
| DpnII | GATC | 1 cut(s) | 1130 |
| Eam1104I | CTCTTC | 1 cut(s) | 1158 |
| EarI | CTCTTC | 1 cut(s) | 1158 |
| Eco130I | CCWWGG | 1 cut(s) | 128 |
| Eco47I | GGWCC | 2 cut(s) | 296, 456 |
| Eco57I | CTGAAG | 2 cut(s) | 48, 357 |
| Eco72I | CACGTG | 1 cut(s) | 428 |
| Eco88I | CYCGRG | 1 cut(s) | 1002 |
| Eco91I | GGTNACC | 1 cut(s) | 860 |
| EcoO109I | RGGNCCY | 1 cut(s) | 296 |
| EcoO65I | GGTNACC | 1 cut(s) | 860 |
| EcoRI | GAATTC | 1 cut(s) | 975 |
| EcoRII | CCWGG | 3 cut(s) | 118, 292, 402 |
| EcoT14I | CCWWGG | 1 cut(s) | 128 |
| EcoT22I | ATGCAT | 3 cut(s) | 496, 546, 1299 |
| ErhI | CCWWGG | 1 cut(s) | 128 |
| Esp3I | CGTCTC | 2 cut(s) | 81, 127 |
| FalI | AAGNNNNNCTT | 2 cut(s) | 849, 881 |
| FaqI | GGGAC | 3 cut(s) | 282, 436, 605 |
| Fnu4HI | GCNGC | 5 cut(s) | 93, 390, 1109, 1442, 1534 |
| FokI | GGATG | 6 cut(s) | 191, 484, 712, 1049, 1067, 1171 |
| Fsp4HI | GCNGC | 5 cut(s) | 93, 390, 1109, 1442, 1534 |
| FspBI | CTAG | 5 cut(s) | 267, 398, 480, 815, 1085 |
| GlaI | GCGC | 1 cut(s) | 1476 |
| GluI | GCNGC | 5 cut(s) | 93, 390, 1109, 1442, 1534 |
| GsaI | CCCAGC | 1 cut(s) | 264 |
| GsuI | CTGGAG | 1 cut(s) | 30 |
| HaeIII | GGCC | 2 cut(s) | 66, 590 |
| HgaI | GACGC | 2 cut(s) | 98, 1447 |
| HhaI | GCGC | 1 cut(s) | 1477 |
| Hin1I | GRCGYC | 1 cut(s) | 90 |
| Hin6I | GCGC | 1 cut(s) | 1475 |
| HinP1I | GCGC | 1 cut(s) | 1475 |
| HincII | GTYRAC | 1 cut(s) | 125 |
| HindII | GTYRAC | 1 cut(s) | 125 |
| HindIII | AAGCTT | 1 cut(s) | 467 |
| HinfI | GANTC | 6 cut(s) | 223, 379, 475, 536, 1447, 1483 |
| HphI | GGTGA | 6 cut(s) | 776, 830, 872, 1219, 1446, 1447 |
| Hpy166II | GTNNAC | 4 cut(s) | 125, 244, 611, 1248 |
| Hpy188I | TCNGA | 5 cut(s) | 363, 376, 384, 951, 990 |
| Hpy188III | TCNNGA | 8 cut(s) | 165, 173, 533, 709, 838, 1002, 1103, 1430 |
| Hpy8I | GTNNAC | 4 cut(s) | 125, 244, 611, 1248 |
| HpyAV | CCTTC | 4 cut(s) | 78, 171, 347, 379 |
| HpyCH4III | ACNGT | 1 cut(s) | 22 |
| HpyCH4IV | ACGT | 1 cut(s) | 427 |
| HpyF10VI | GCNNNNNNNGC | 4 cut(s) | 217, 398, 1294, 1472 |
| HpySE526I | ACGT | 1 cut(s) | 427 |
| Hsp92I | GRCGYC | 1 cut(s) | 90 |
| HspAI | GCGC | 1 cut(s) | 1475 |
| Kzo9I | GATC | 1 cut(s) | 1130 |
| LmnI | GCTCC | 1 cut(s) | 118 |
| Lsp1109I | GCAGC | 3 cut(s) | 376, 1120, 1453 |
| LweI | GCATC | 3 cut(s) | 169, 503, 1193 |
| MaeI | CTAG | 5 cut(s) | 267, 398, 480, 815, 1085 |
| MaeII | ACGT | 1 cut(s) | 427 |
| MaeIII | GTNAC | 8 cut(s) | 508, 706, 733, 860, 961, 1030, 1342, 1435 |
| MalI | GATC | 1 cut(s) | 1132 |
| MboI | GATC | 1 cut(s) | 1130 |
| MboII | GAAGA | 8 cut(s) | 26, 41, 119, 200, 779, 794, 1145, 1224 |
| MfeI | CAATTG | 3 cut(s) | 516, 558, 1140 |
| MhlI | GDGCHC | 2 cut(s) | 1018, 1278 |
| MlyI | GAGTC | 3 cut(s) | 232, 469, 545 |
| Mph1103I | ATGCAT | 3 cut(s) | 496, 546, 1299 |
| MroXI | GAANNNNTTC | 1 cut(s) | 1524 |
| MseI | TTAA | 5 cut(s) | 440, 579, 630, 909, 996 |
| MslI | CAYNNNNRTG | 3 cut(s) | 1205, 1296, 1328 |
| MspA1I | CMGCKG | 2 cut(s) | 95, 1536 |
| MspR9I | CCNGG | 3 cut(s) | 120, 294, 404 |
| MunI | CAATTG | 3 cut(s) | 516, 558, 1140 |
| Mva1269I | GAATGC | 2 cut(s) | 696, 1468 |
| MvaI | CCWGG | 3 cut(s) | 120, 294, 404 |
| MwoI | GCNNNNNNNGC | 4 cut(s) | 217, 398, 1294, 1472 |
| NcoI | CCATGG | 1 cut(s) | 128 |
| NdeII | GATC | 1 cut(s) | 1130 |
| NheI | GCTAGC | 1 cut(s) | 1084 |
| NlaIV | GGNNCC | 1 cut(s) | 298 |
| NmeAIII | GCCGAG | 1 cut(s) | 246 |
| NmuCI | GTSAC | 4 cut(s) | 706, 860, 961, 1435 |
| NsiI | ATGCAT | 3 cut(s) | 496, 546, 1299 |
| NspI | RCATGY | 6 cut(s) | 211, 927, 1084, 1274, 1297, 1301 |
| OliI | CACNNNNGTG | 1 cut(s) | 1205 |
| PaeI | GCATGC | 2 cut(s) | 1084, 1301 |
| PaeR7I | CTCGAG | 1 cut(s) | 1002 |
| PasI | CCCWGGG | 1 cut(s) | 403 |
| PciI | ACATGT | 2 cut(s) | 923, 1270 |
| PctI | GAATGC | 2 cut(s) | 696, 1468 |
| PdmI | GAANNNNTTC | 1 cut(s) | 1524 |
| PfeI | GAWTC | 3 cut(s) | 379, 1447, 1483 |
| PflFI | GACNNNGTC | 1 cut(s) | 454 |
| PkrI | GCNGC | 5 cut(s) | 94, 391, 1110, 1443, 1535 |
| PleI | GAGTC | 3 cut(s) | 231, 469, 544 |
| PmaCI | CACGTG | 1 cut(s) | 428 |
| PmlI | CACGTG | 1 cut(s) | 428 |
| PpsI | GAGTC | 3 cut(s) | 231, 469, 544 |
| Ppu21I | YACGTR | 1 cut(s) | 428 |
| PpuMI | RGGWCCY | 1 cut(s) | 296 |
| PscI | ACATGT | 2 cut(s) | 923, 1270 |
| PshBI | ATTAAT | 1 cut(s) | 630 |
| Psp5II | RGGWCCY | 1 cut(s) | 296 |
| Psp6I | CCWGG | 3 cut(s) | 118, 292, 402 |
| PspCI | CACGTG | 1 cut(s) | 428 |
| PspEI | GGTNACC | 1 cut(s) | 860 |
| PspFI | CCCAGC | 1 cut(s) | 260 |
| PspGI | CCWGG | 3 cut(s) | 118, 292, 402 |
| PspN4I | GGNNCC | 1 cut(s) | 298 |
| PspPI | GGNCC | 4 cut(s) | 65, 296, 456, 589 |
| PspPPI | RGGWCCY | 1 cut(s) | 296 |
| PstI | CTGCAG | 1 cut(s) | 421 |
| PstNI | CAGNNNCTG | 3 cut(s) | 623, 737, 1114 |
| PsyI | GACNNNGTC | 1 cut(s) | 454 |
| PvuII | CAGCTG | 1 cut(s) | 1536 |
| RseI | CAYNNNNRTG | 3 cut(s) | 1205, 1296, 1328 |
| SaqAI | TTAA | 5 cut(s) | 440, 579, 630, 909, 996 |
| SatI | GCNGC | 5 cut(s) | 93, 390, 1109, 1442, 1534 |
| Sau3AI | GATC | 1 cut(s) | 1130 |
| Sau96I | GGNCC | 4 cut(s) | 65, 296, 456, 589 |
| SbfI | CCTGCAGG | 1 cut(s) | 421 |
| SchI | GAGTC | 3 cut(s) | 232, 469, 545 |
| ScrFI | CCNGG | 3 cut(s) | 120, 294, 404 |
| SdaI | CCTGCAGG | 1 cut(s) | 421 |
| SduI | GDGCHC | 2 cut(s) | 1018, 1278 |
| SfaNI | GCATC | 3 cut(s) | 169, 503, 1193 |
| SfcI | CTRYAG | 2 cut(s) | 417, 777 |
| Sfr274I | CTCGAG | 1 cut(s) | 1002 |
| SinI | GGWCC | 2 cut(s) | 296, 456 |
| SlaI | CTCGAG | 1 cut(s) | 1002 |
| SmiMI | CAYNNNNRTG | 3 cut(s) | 1205, 1296, 1328 |
| SmlI | CTYRAG | 5 cut(s) | 173, 836, 1002, 1103, 1509 |
| SmoI | CTYRAG | 5 cut(s) | 173, 836, 1002, 1103, 1509 |
| SphI | GCATGC | 2 cut(s) | 1084, 1301 |
| Sse8387I | CCTGCAGG | 1 cut(s) | 421 |
| SsiI | CCGC | 2 cut(s) | 93, 762 |
| SspMI | CTAG | 5 cut(s) | 267, 398, 480, 815, 1085 |
| StyD4I | CCNGG | 3 cut(s) | 118, 292, 402 |
| StyI | CCWWGG | 1 cut(s) | 128 |
| TaaI | ACNGT | 1 cut(s) | 22 |
| TaiI | ACGT | 1 cut(s) | 430 |
| TaqI | TCGA | 3 cut(s) | 796, 1003, 1414 |
| TauI | GCSGC | 1 cut(s) | 95 |
| TfiI | GAWTC | 3 cut(s) | 379, 1447, 1483 |
| Tru1I | TTAA | 5 cut(s) | 440, 579, 630, 909, 996 |
| Tru9I | TTAA | 5 cut(s) | 440, 579, 630, 909, 996 |
| TscAI | CASTG | 3 cut(s) | 289, 748, 1257 |
| TseFI | GTSAC | 4 cut(s) | 706, 860, 961, 1435 |
| TseI | GCWGC | 4 cut(s) | 389, 1108, 1441, 1533 |
| Tsp45I | GTSAC | 4 cut(s) | 706, 860, 961, 1435 |
| TspDTI | ATGAA | 5 cut(s) | 500, 593, 1272, 1517, 1518 |
| TspRI | CASTG | 3 cut(s) | 289, 748, 1257 |
| Tth111I | GACNNNGTC | 1 cut(s) | 454 |
| VpaK11BI | GGWCC | 2 cut(s) | 296, 456 |
| VspI | ATTAAT | 1 cut(s) | 630 |
| XapI | RAATTY | 4 cut(s) | 798, 975, 1217, 1357 |
| XceI | RCATGY | 6 cut(s) | 211, 927, 1084, 1274, 1297, 1301 |
| XcmI | CCANNNNNNNNNTGG | 1 cut(s) | 400 |
| XhoI | CTCGAG | 1 cut(s) | 1002 |
| XmnI | GAANNNNTTC | 1 cut(s) | 1524 |
| XspI | CTAG | 5 cut(s) | 267, 398, 480, 815, 1085 |
| Zsp2I | ATGCAT | 3 cut(s) | 496, 546, 1299 |