RLG00000024350

The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins. Some of these proteins have been shown both in vivo and in vitro to have ubiquitin E3 ligase activity.

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
rosa_laevigata
Chr5
OG0007518
Physical Location & Seq
Forward (+)
35019496 .. 35023983
4488 bp
Loading structure...
UTR
Exon/CDS
Intron
RLM00000024350

Sequence Viewer

Length: 1389 bp
ATGGTAATTGAAGAAGAAGCTTCTGCTAAGGAAAATGATGCTGGCATTTCCGCCAGCGAAGTTGACCCTTCAACCCAACAGGATGGAAACTCCACTGAGATAATTGAAGAAACTCCTCCTGGTCACCCATGGAGACGACAAAACCTCGCCTTACAGATACCCACCAGAACTGTTGAGGATCCCGAAGAGGATTTTGTGAGAATAGACATGCCGAGAACGCCAAGTCCGACTCCGAAAAGAGTAAACTTCTCCCCATTACCCAGCCCTAGTTTAAACAAAATCAGTGGATCCCCAGGTCCCTCATCCTCAAAAACTAAGTCAACCATAAAAAGCCTCCTTCCAAAACTAAGTTTCAAGTATCGGAACACTACTTCAGAGATTCGGAAGGCTGCTACTCTTGCACTAGGAGGAACACCTACAGCTACCCGTGAGAAGCCTTCAATTTCTAGGACATTTTCTCTTCCAAAGCTTTTAACACCTAGACTGAAGAATACGTCATCCTTGCCTACAACCCCAATTGCTCACTCAAATCCAGAGTCTATGCATGGAAGAAACACAACTGATCTGAAAGGAGGGCGCCAACTGCCTATTCATCGTTCACATTCGGTCCCTGAGCTTAATAAAGATGGGAGTGTAGGTCTAGGTAGTGTCTTTCGAGTAATTCCTACCACACCACGAGCGATGGAGAGAAGTGTATCAATAACTTCATGCACCTCCCCAAAGGATGACAATGATGGAAGTGATGACGATGGTGAAGATATTGCCGAAGAAGAAGCTGTCTGTCGAATTTGCTTAGTTGAATTGGGGGAAGGTGCTGACACCCTCAAGATGGAATGCAGCTGTAAAGGTGACCTCGCTCTAGCCCACCAAGAGTGTGCTGTAAAATGGTTCAGCATTAAAGGTAATAAAACATGTGATGTGTGCAAGCAAGAGGTCCAGAACCTACCTGTCACGCTTTTACGAATTCAAAATGTTCAAGCCCATAATTTACGAGGAACTAGAGCACAGCAGCCTGAGGTTACTCAATATAGGGTTTGGCAGGATGTTCCAATTCTCGTCATAGTTAGCATGCTCGCATACTTCTGTTTTCTTGAGCAGCTTCTGGTAGGAAAAATGGGATCAGGTGCAATTGCACTCTCTCTTCCTTTTTCCTGTATATTGGGTCTTTTGGCATCCATGACAGCAACCACAATGGGTAGGCAAGCTTGCAATTCTTCAGTCGTACAGTATTTTACTTCCATTAACCAATCTTCTATTACTGATTTGAAATTTGTGCACAGTGAAAAGAAAATACGTCTGGGTTTATGCAACCATTCAGTTTGCCTTGGTGGTTCTCTCAGCTCATTTACTTTATTCATTGGTAAGACATGCTCTGCTGACATTAAGTAG
Functional Annotation
Gene Ontology
Molecular Function
Biological Process
Cellular Component
No ontology terms assigned.
KEGG Pathways
Metabolic & Signaling
No pathways identified.
Pfam Domains
Protein Families
RINGv

Protein Analysis

463

Amino Acids

50.18

Weight (kDa)

7.89

Isoelectric Point (pI)

52.23

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
RINGv PF12906 261 - 308 6.4e-13 RING-variant domain
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
Loading...
Style Settings
Image
Tree File
Tip: Beautify your tree with professional tools

Download the Full Tree (.nwk) file, then upload it to any of the following tools to customize colors, fonts, annotations, clades, and branch support.

Publication-ready
iTOL Interactive Tree Of Life · Most popular EvolView Flexible annotations MEGA Desktop phylogenetics suite FigTree Desktop tree editor

Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AccB1I GGYRCC 1 cut(s) 576
AciI CCGC 1 cut(s) 51
AclWI GGATC 5 cut(s) 173, 186, 282, 295, 1126
AcsI RAATTY 3 cut(s) 786, 963, 1268
AcuI CTGAAG 3 cut(s) 357, 506, 1200
AcyI GRCGYC 1 cut(s) 577
AfaI GTAC 1 cut(s) 1224
AfiI CCNNNNNNNGG 1 cut(s) 829
AflIII ACRYGT 1 cut(s) 911
AgsI TTSAA 9 cut(s) 11, 72, 107, 355, 441, 800, 968, 977, 1267
AjnI CCWGG 2 cut(s) 118, 292
AjuI GAANNNNNNNTTGG 2 cut(s) 573, 605
AloI GAACNNNNNNTCC 2 cut(s) 208, 240
AluBI AGCT 9 cut(s) 20, 422, 469, 616, 776, 840, 1099, 1205, 1341
AluI AGCT 9 cut(s) 20, 422, 469, 616, 776, 840, 1099, 1205, 1341
Alw21I GWGCWC 2 cut(s) 1006, 1278
Alw26I GTCTC 1 cut(s) 127
Alw44I GTGCAC 1 cut(s) 1274
AlwI GGATC 5 cut(s) 173, 186, 282, 295, 1126
AlwNI CAGNNNCTG 1 cut(s) 1102
ApaLI GTGCAC 1 cut(s) 1274
ApeKI GCWGC 4 cut(s) 389, 837, 1009, 1096
ApoI RAATTY 3 cut(s) 786, 963, 1268
ArsI GACNNNNNNTTYG 4 cut(s) 302, 334, 521, 553
AspLEI GCGC 1 cut(s) 579
AspS9I GGNCC 3 cut(s) 296, 607, 934
AsuHPI GGTGA 3 cut(s) 116, 764, 860
AvaII GGWCC 3 cut(s) 296, 607, 934
AxyI CCTNAGG 1 cut(s) 1014
BaeGI GKGCMC 1 cut(s) 1278
BamHI GGATCC 2 cut(s) 178, 287
BanI GGYRCC 1 cut(s) 576
BauI CACGAG 1 cut(s) 675
Bbv12I GWGCWC 2 cut(s) 1006, 1278
BbvI GCAGC 4 cut(s) 376, 849, 1021, 1108
BccI CCATC 6 cut(s) 77, 620, 676, 728, 743, 823
BciT130I CCWGG 2 cut(s) 120, 294
BcoDI GTCTC 1 cut(s) 127
BfaI CTAG 7 cut(s) 267, 404, 447, 480, 641, 860, 999
BfmI CTRYAG 1 cut(s) 417
BfoI RGCGCY 1 cut(s) 580
BisI GCNGC 4 cut(s) 390, 838, 1010, 1097
BlsI GCNGC 4 cut(s) 391, 839, 1011, 1098
Bme1390I CCNGG 2 cut(s) 120, 294
Bme18I GGWCC 3 cut(s) 296, 607, 934
BmgT120I GGNCC 3 cut(s) 296, 607, 934
BmiI GGNNCC 5 cut(s) 180, 289, 298, 578, 609
BmrFI CCNGG 2 cut(s) 120, 294
BmsI GCATC 2 cut(s) 28, 1181
Bpu10I CCTNAGC 2 cut(s) 27, 612
BpuEI CTTGAG 2 cut(s) 809, 1112
BsaHI GRCGYC 1 cut(s) 577
BsaJI CCNNGG 3 cut(s) 128, 292, 1324
BsaXI ACNNNNNCTCC 2 cut(s) 622, 652
Bsc4I CCNNNNNNNGG 1 cut(s) 829
Bse21I CCTNAGG 1 cut(s) 1014
BseBI CCWGG 2 cut(s) 120, 294
BseDI CCNNGG 3 cut(s) 128, 292, 1324
BseGI GGATG 6 cut(s) 88, 302, 497, 730, 1048, 1172
BseLI CCNNNNNNNGG 1 cut(s) 829
BseMII CTCAG 4 cut(s) 87, 603, 1005, 1351
BseRI GAGGAG 1 cut(s) 105
BseSI GKGCMC 1 cut(s) 1278
BseXI GCAGC 4 cut(s) 376, 849, 1021, 1108
BseYI CCCAGC 1 cut(s) 260
BshNI GGYRCC 1 cut(s) 576
BsiHKAI GWGCWC 2 cut(s) 1006, 1278
BslFI GGGAC 2 cut(s) 282, 593
BslI CCNNNNNNNGG 1 cut(s) 829
BsmAI GTCTC 1 cut(s) 127
BsmBI CGTCTC 1 cut(s) 127
BsmFI GGGAC 2 cut(s) 282, 593
BsmI GAATGC 1 cut(s) 839
Bsp1286I GDGCHC 2 cut(s) 1006, 1278
Bsp143I GATC 4 cut(s) 178, 287, 562, 1118
Bsp19I CCATGG 1 cut(s) 128
BspACI CCGC 1 cut(s) 51
BspCNI CTCAG 4 cut(s) 88, 604, 1006, 1350
BspLI GGNNCC 5 cut(s) 180, 289, 298, 578, 609
BspPI GGATC 5 cut(s) 173, 186, 282, 295, 1126
BspT107I GGYRCC 1 cut(s) 576
BssECI CCNNGG 3 cut(s) 128, 292, 1324
BssMI GATC 4 cut(s) 178, 287, 562, 1118
BssNI GRCGYC 1 cut(s) 577
BssSI CACGAG 1 cut(s) 675
BssT1I CCWWGG 2 cut(s) 128, 1324
Bst2BI CACGAG 1 cut(s) 675
Bst2UI CCWGG 2 cut(s) 120, 294
Bst4CI ACNGT 3 cut(s) 172, 1227, 1280
Bst6I CTCTTC 3 cut(s) 180, 465, 1146
BstACI GRCGYC 1 cut(s) 577
BstC8I GCNNGC 7 cut(s) 43, 55, 926, 1070, 1074, 1203, 1207
BstDEI CTNAG 8 cut(s) 27, 96, 315, 347, 612, 793, 1014, 1337
BstDSI CCRYGG 1 cut(s) 128
BstEII GGTNACC 2 cut(s) 122, 848
BstF5I GGATG 6 cut(s) 88, 302, 497, 730, 1048, 1172
BstH2I RGCGCY 1 cut(s) 580
BstHHI GCGC 1 cut(s) 579
BstKTI GATC 4 cut(s) 181, 290, 565, 1121
BstMAI GTCTC 1 cut(s) 127
BstMBI GATC 4 cut(s) 178, 287, 562, 1118
BstMWI GCNNNNNNNGC 3 cut(s) 217, 398, 583
BstNI CCWGG 2 cut(s) 120, 294
BstNSI RCATGY 4 cut(s) 211, 915, 1072, 1371
BstPI GGTNACC 2 cut(s) 122, 848
BstSCI CCNGG 2 cut(s) 118, 292
BstSFI CTRYAG 1 cut(s) 417
BstSLI GKGCMC 1 cut(s) 1278
BstV1I GCAGC 4 cut(s) 376, 849, 1021, 1108
BstX2I RGATCY 2 cut(s) 178, 287
BstXI CCANNNNNNTGG 1 cut(s) 83
BstYI RGATCY 2 cut(s) 178, 287
Bsu36I CCTNAGG 1 cut(s) 1014
BtgI CCRYGG 1 cut(s) 128
BtgZI GCGATG 1 cut(s) 695
BtsCI GGATG 6 cut(s) 88, 302, 497, 730, 1048, 1172
BtsIMutI CAGTG 3 cut(s) 93, 289, 1285
Cac8I GCNNGC 7 cut(s) 43, 55, 926, 1070, 1074, 1203, 1207
CaiI CAGNNNCTG 1 cut(s) 1102
CfoI GCGC 1 cut(s) 579
Cfr13I GGNCC 3 cut(s) 296, 607, 934
Csp6I GTAC 1 cut(s) 1223
CspCI CAANNNNNGTGG 2 cut(s) 265, 300
CviAII CATG 8 cut(s) 129, 208, 545, 708, 912, 1069, 1177, 1368
CviQI GTAC 1 cut(s) 1223
DdeI CTNAG 8 cut(s) 27, 96, 315, 347, 612, 793, 1014, 1337
DinI GGCGCC 1 cut(s) 578
DpnI GATC 4 cut(s) 180, 289, 564, 1120
DpnII GATC 4 cut(s) 178, 287, 562, 1118
DraI TTTAAA 1 cut(s) 273
Eam1104I CTCTTC 3 cut(s) 180, 465, 1146
EarI CTCTTC 3 cut(s) 180, 465, 1146
EciI GGCGGA 1 cut(s) 40
Eco130I CCWWGG 2 cut(s) 128, 1324
Eco47I GGWCC 3 cut(s) 296, 607, 934
Eco57I CTGAAG 3 cut(s) 357, 506, 1200
Eco81I CCTNAGG 1 cut(s) 1014
Eco91I GGTNACC 2 cut(s) 122, 848
EcoO109I RGGNCCY 1 cut(s) 296
EcoO65I GGTNACC 2 cut(s) 122, 848
EcoRI GAATTC 1 cut(s) 963
EcoRII CCWGG 2 cut(s) 118, 292
EcoT14I CCWWGG 2 cut(s) 128, 1324
EcoT22I ATGCAT 1 cut(s) 546
EgeI GGCGCC 1 cut(s) 578
EheI GGCGCC 1 cut(s) 578
ErhI CCWWGG 2 cut(s) 128, 1324
Esp3I CGTCTC 1 cut(s) 127
FaeI CATG 8 cut(s) 132, 211, 548, 711, 915, 1072, 1180, 1371
FaqI GGGAC 2 cut(s) 282, 593
FatI CATG 8 cut(s) 128, 207, 544, 707, 911, 1068, 1176, 1367
Fnu4HI GCNGC 4 cut(s) 390, 838, 1010, 1097
FokI GGATG 6 cut(s) 95, 289, 484, 737, 1055, 1159
Fsp4HI GCNGC 4 cut(s) 390, 838, 1010, 1097
FspBI CTAG 7 cut(s) 267, 404, 447, 480, 641, 860, 999
GlaI GCGC 1 cut(s) 578
GluI GCNGC 4 cut(s) 390, 838, 1010, 1097
GsaI CCCAGC 1 cut(s) 264
HaeII RGCGCY 1 cut(s) 580
HhaI GCGC 1 cut(s) 579
Hin1I GRCGYC 1 cut(s) 577
Hin1II CATG 8 cut(s) 132, 211, 548, 711, 915, 1072, 1180, 1371
Hin6I GCGC 1 cut(s) 577
HinP1I GCGC 1 cut(s) 577
HincII GTYRAC 2 cut(s) 64, 321
HindII GTYRAC 2 cut(s) 64, 321
HindIII AAGCTT 3 cut(s) 18, 467, 1203
HinfI GANTC 3 cut(s) 229, 379, 536
HphI GGTGA 3 cut(s) 116, 764, 860
Hpy166II GTNNAC 5 cut(s) 64, 244, 321, 599, 1276
Hpy188I TCNGA 6 cut(s) 228, 234, 363, 376, 384, 567
Hpy188III TCNNGA 5 cut(s) 182, 533, 826, 937, 1091
Hpy8I GTNNAC 5 cut(s) 64, 244, 321, 599, 1276
HpyAV CCTTC 5 cut(s) 78, 347, 379, 447, 803
HpyCH4III ACNGT 3 cut(s) 172, 1227, 1280
HpyCH4IV ACGT 2 cut(s) 494, 1294
HpyF10VI GCNNNNNNNGC 3 cut(s) 217, 398, 583
HpyF3I CTNAG 8 cut(s) 27, 96, 315, 347, 612, 793, 1014, 1337
HpySE526I ACGT 2 cut(s) 494, 1294
Hsp92I GRCGYC 1 cut(s) 577
Hsp92II CATG 8 cut(s) 132, 211, 548, 711, 915, 1072, 1180, 1371
HspAI GCGC 1 cut(s) 577
KasI GGCGCC 1 cut(s) 576
Kzo9I GATC 4 cut(s) 178, 287, 562, 1118
Lsp1109I GCAGC 4 cut(s) 376, 849, 1021, 1108
LweI GCATC 2 cut(s) 28, 1181
MaeI CTAG 7 cut(s) 267, 404, 447, 480, 641, 860, 999
MaeII ACGT 2 cut(s) 494, 1294
MaeIII GTNAC 4 cut(s) 122, 848, 949, 1018
MalI GATC 4 cut(s) 180, 289, 564, 1120
MboI GATC 4 cut(s) 178, 287, 562, 1118
MfeI CAATTG 2 cut(s) 516, 1128
MflI RGATCY 2 cut(s) 178, 287
MhlI GDGCHC 2 cut(s) 1006, 1278
Mly113I GGCGCC 1 cut(s) 577
MlyI GAGTC 2 cut(s) 223, 545
MmeI TCCRAC 1 cut(s) 251
Mph1103I ATGCAT 1 cut(s) 546
MseI TTAA 6 cut(s) 272, 473, 618, 897, 1242, 1383
MspA1I CMGCKG 1 cut(s) 840
MspR9I CCNGG 2 cut(s) 120, 294
MssI GTTTAAAC 1 cut(s) 273
MunI CAATTG 2 cut(s) 516, 1128
Mva1269I GAATGC 1 cut(s) 839
MvaI CCWGG 2 cut(s) 120, 294
MwoI GCNNNNNNNGC 3 cut(s) 217, 398, 583
NarI GGCGCC 1 cut(s) 577
NcoI CCATGG 1 cut(s) 128
NdeII GATC 4 cut(s) 178, 287, 562, 1118
NlaIII CATG 8 cut(s) 132, 211, 548, 711, 915, 1072, 1180, 1371
NlaIV GGNNCC 5 cut(s) 180, 289, 298, 578, 609
NmeAIII GCCGAG 1 cut(s) 237
NmuCI GTSAC 3 cut(s) 122, 848, 949
NsiI ATGCAT 1 cut(s) 546
NspI RCATGY 4 cut(s) 211, 915, 1072, 1371
PaeI GCATGC 1 cut(s) 1072
PciI ACATGT 1 cut(s) 911
PcsI WCGNNNNNNNCGW 1 cut(s) 224
PctI GAATGC 1 cut(s) 839
PfeI GAWTC 1 cut(s) 379
PkrI GCNGC 4 cut(s) 391, 839, 1011, 1098
PleI GAGTC 2 cut(s) 223, 544
PluTI GGCGCC 1 cut(s) 580
PmeI GTTTAAAC 1 cut(s) 273
PpsI GAGTC 2 cut(s) 223, 544
PpuMI RGGWCCY 1 cut(s) 296
PscI ACATGT 1 cut(s) 911
Psp5II RGGWCCY 1 cut(s) 296
Psp6I CCWGG 2 cut(s) 118, 292
PspEI GGTNACC 2 cut(s) 122, 848
PspFI CCCAGC 1 cut(s) 260
PspGI CCWGG 2 cut(s) 118, 292
PspN4I GGNNCC 5 cut(s) 180, 289, 298, 578, 609
PspPI GGNCC 3 cut(s) 296, 607, 934
PspPPI RGGWCCY 1 cut(s) 296
PstNI CAGNNNCTG 1 cut(s) 1102
PsuI RGATCY 2 cut(s) 178, 287
PvuII CAGCTG 1 cut(s) 840
RsaI GTAC 1 cut(s) 1224
RsaNI GTAC 1 cut(s) 1223
SaqAI TTAA 6 cut(s) 272, 473, 618, 897, 1242, 1383
SatI GCNGC 4 cut(s) 390, 838, 1010, 1097
Sau3AI GATC 4 cut(s) 178, 287, 562, 1118
Sau96I GGNCC 3 cut(s) 296, 607, 934
SchI GAGTC 2 cut(s) 223, 545
ScrFI CCNGG 2 cut(s) 120, 294
SduI GDGCHC 2 cut(s) 1006, 1278
SfaNI GCATC 2 cut(s) 28, 1181
SfcI CTRYAG 1 cut(s) 417
SfoI GGCGCC 1 cut(s) 578
SinI GGWCC 3 cut(s) 296, 607, 934
SmlI CTYRAG 2 cut(s) 824, 1091
SmoI CTYRAG 2 cut(s) 824, 1091
SphI GCATGC 1 cut(s) 1072
SsiI CCGC 1 cut(s) 51
SspDI GGCGCC 1 cut(s) 576
SspMI CTAG 7 cut(s) 267, 404, 447, 480, 641, 860, 999
StyD4I CCNGG 2 cut(s) 118, 292
StyI CCWWGG 2 cut(s) 128, 1324
TaaI ACNGT 3 cut(s) 172, 1227, 1280
TaiI ACGT 2 cut(s) 497, 1297
TaqI TCGA 2 cut(s) 655, 784
TaqII GACCGA 1 cut(s) 595
TfiI GAWTC 1 cut(s) 379
Tru1I TTAA 6 cut(s) 272, 473, 618, 897, 1242, 1383
Tru9I TTAA 6 cut(s) 272, 473, 618, 897, 1242, 1383
TscAI CASTG 3 cut(s) 100, 289, 1285
TseFI GTSAC 3 cut(s) 122, 848, 949
TseI GCWGC 4 cut(s) 389, 837, 1009, 1096
Tsp45I GTSAC 3 cut(s) 122, 848, 949
TspDTI ATGAA 3 cut(s) 581, 696, 1345
TspRI CASTG 3 cut(s) 100, 289, 1285
VneI GTGCAC 1 cut(s) 1274
VpaK11BI GGWCC 3 cut(s) 296, 607, 934
XapI RAATTY 3 cut(s) 786, 963, 1268
XceI RCATGY 4 cut(s) 211, 915, 1072, 1371
XspI CTAG 7 cut(s) 267, 404, 447, 480, 641, 860, 999
Zsp2I ATGCAT 1 cut(s) 546
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.