The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins. Some of these proteins have been shown both in vivo and in vitro to have ubiquitin E3 ligase activity.
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| Species | Orthologous Gene IDs |
|---|---|
| fragaria_vesca | FvH4_6g15720 FvH4_6g15720 FvH4_6g15720 FvH4_6g15720 FvH4_6g15720 FvH4_6g15720 FvH4_6g15720 FvH4_6g15720 |
| malus_domestica | MD04G1099800.v1.1 MD12G1119900.v1.1 |
| prunus_persica | Prupe.6G238100_v2.0.a1 Prupe.6G238100_v2.0.a1 |
| pyrus_communis | pycom04g09490 pycom12g11880 |
| rosa_chinensis | RchiOBHm_Chr3g0469421 |
| rosa_laevigata | RLG00000024350 |
| rosa_multiflora | Rmu_sc0005274.1_g000008 |
| rosa_roxburghii | Rroxscaffold_6G00411900 |
| rosa_rugosa | Rorug03G0101700 Rorug03G0101700 |
| rosa_samantha | Rh3AG150700 Rh3BG174400 Rh3CG165400 Rh3DG201000 |
| rosa_wichuraiana | Rw3G014210 |
| Enzyme | Recognition Site | Cut Count | Positions (bp) |
|---|---|---|---|
| AccB1I | GGYRCC | 1 cut(s) | 588 |
| AciI | CCGC | 3 cut(s) | 51, 183, 1322 |
| AclWI | GGATC | 5 cut(s) | 173, 186, 282, 295, 1027 |
| AcsI | RAATTY | 4 cut(s) | 798, 888, 1246, 1383 |
| AcuI | CTGAAG | 3 cut(s) | 357, 506, 1416 |
| AcyI | GRCGYC | 1 cut(s) | 589 |
| AdeI | CACNNNGTG | 1 cut(s) | 1239 |
| AfaI | GTAC | 3 cut(s) | 412, 708, 1315 |
| AfiI | CCNNNNNNNGG | 1 cut(s) | 840 |
| AgsI | TTSAA | 9 cut(s) | 11, 107, 355, 441, 812, 893, 902, 1376, 1388 |
| AjnI | CCWGG | 2 cut(s) | 118, 292 |
| AjuI | GAANNNNNNNTTGG | 2 cut(s) | 585, 617 |
| AleI | CACNNNNGTG | 1 cut(s) | 1094 |
| Alw21I | GWGCWC | 1 cut(s) | 931 |
| Alw26I | GTCTC | 2 cut(s) | 127, 1349 |
| AlwI | GGATC | 5 cut(s) | 173, 186, 282, 295, 1027 |
| AlwNI | CAGNNNCTG | 2 cut(s) | 623, 1003 |
| ApeKI | GCWGC | 6 cut(s) | 389, 848, 934, 997, 1369, 1410 |
| ApoI | RAATTY | 4 cut(s) | 798, 888, 1246, 1383 |
| ArsI | GACNNNNNNTTYG | 4 cut(s) | 302, 334, 521, 553 |
| Asp700I | GAANNNNTTC | 1 cut(s) | 1401 |
| AspLEI | GCGC | 1 cut(s) | 591 |
| AspS9I | GGNCC | 2 cut(s) | 296, 859 |
| AsuHPI | GGTGA | 5 cut(s) | 63, 116, 776, 1108, 1336 |
| AvaII | GGWCC | 2 cut(s) | 296, 859 |
| AxyI | CCTNAGG | 1 cut(s) | 939 |
| BamHI | GGATCC | 2 cut(s) | 178, 287 |
| BanI | GGYRCC | 1 cut(s) | 588 |
| Bbv12I | GWGCWC | 1 cut(s) | 931 |
| BbvI | GCAGC | 5 cut(s) | 376, 860, 946, 1009, 1381 |
| BccI | CCATC | 7 cut(s) | 77, 632, 688, 740, 755, 834, 1278 |
| BciT130I | CCWGG | 2 cut(s) | 120, 294 |
| BcoDI | GTCTC | 2 cut(s) | 127, 1349 |
| BfaI | CTAG | 6 cut(s) | 267, 404, 447, 480, 653, 924 |
| BfmI | CTRYAG | 1 cut(s) | 417 |
| BfoI | RGCGCY | 1 cut(s) | 592 |
| BisI | GCNGC | 6 cut(s) | 390, 849, 935, 998, 1370, 1411 |
| BlsI | GCNGC | 6 cut(s) | 391, 850, 936, 999, 1371, 1412 |
| Bme1390I | CCNGG | 2 cut(s) | 120, 294 |
| Bme18I | GGWCC | 2 cut(s) | 296, 859 |
| BmgT120I | GGNCC | 2 cut(s) | 296, 859 |
| BmiI | GGNNCC | 4 cut(s) | 180, 289, 298, 590 |
| BmrFI | CCNGG | 2 cut(s) | 120, 294 |
| BmsI | GCATC | 2 cut(s) | 28, 1082 |
| Bpu10I | CCTNAGC | 2 cut(s) | 27, 624 |
| BpuEI | CTTGAG | 3 cut(s) | 820, 837, 1013 |
| BsaHI | GRCGYC | 1 cut(s) | 589 |
| BsaJI | CCNNGG | 4 cut(s) | 128, 292, 1140, 1364 |
| BsaXI | ACNNNNNCTCC | 2 cut(s) | 634, 664 |
| Bsc4I | CCNNNNNNNGG | 1 cut(s) | 840 |
| Bse1I | ACTGG | 1 cut(s) | 1225 |
| Bse21I | CCTNAGG | 1 cut(s) | 939 |
| BseBI | CCWGG | 2 cut(s) | 120, 294 |
| BseDI | CCNNGG | 4 cut(s) | 128, 292, 1140, 1364 |
| BseGI | GGATG | 6 cut(s) | 88, 302, 497, 742, 949, 1073 |
| BseLI | CCNNNNNNNGG | 1 cut(s) | 840 |
| BseMII | CTCAG | 4 cut(s) | 87, 615, 930, 1167 |
| BseNI | ACTGG | 1 cut(s) | 1225 |
| BseRI | GAGGAG | 1 cut(s) | 105 |
| BseXI | GCAGC | 5 cut(s) | 376, 860, 946, 1009, 1381 |
| BseYI | CCCAGC | 2 cut(s) | 260, 1329 |
| BshNI | GGYRCC | 1 cut(s) | 588 |
| BsiHKAI | GWGCWC | 1 cut(s) | 931 |
| BsiSI | CCGG | 1 cut(s) | 1319 |
| BslFI | GGGAC | 3 cut(s) | 210, 282, 605 |
| BslI | CCNNNNNNNGG | 1 cut(s) | 840 |
| BsmAI | GTCTC | 2 cut(s) | 127, 1349 |
| BsmBI | CGTCTC | 1 cut(s) | 127 |
| BsmFI | GGGAC | 3 cut(s) | 210, 282, 605 |
| BsmI | GAATGC | 1 cut(s) | 850 |
| Bsp1286I | GDGCHC | 1 cut(s) | 931 |
| Bsp143I | GATC | 4 cut(s) | 178, 287, 562, 1019 |
| Bsp19I | CCATGG | 1 cut(s) | 128 |
| BspACI | CCGC | 3 cut(s) | 51, 183, 1322 |
| BspCNI | CTCAG | 4 cut(s) | 88, 616, 931, 1166 |
| BspLI | GGNNCC | 4 cut(s) | 180, 289, 298, 590 |
| BspPI | GGATC | 5 cut(s) | 173, 186, 282, 295, 1027 |
| BspT107I | GGYRCC | 1 cut(s) | 588 |
| BsrI | ACTGG | 1 cut(s) | 1225 |
| BssECI | CCNNGG | 4 cut(s) | 128, 292, 1140, 1364 |
| BssMI | GATC | 4 cut(s) | 178, 287, 562, 1019 |
| BssNI | GRCGYC | 1 cut(s) | 589 |
| BssT1I | CCWWGG | 2 cut(s) | 128, 1140 |
| Bst2UI | CCWGG | 2 cut(s) | 120, 294 |
| Bst4CI | ACNGT | 1 cut(s) | 172 |
| Bst6I | CTCTTC | 2 cut(s) | 465, 1047 |
| BstACI | GRCGYC | 1 cut(s) | 589 |
| BstC8I | GCNNGC | 5 cut(s) | 43, 55, 971, 975, 1188 |
| BstDEI | CTNAG | 8 cut(s) | 27, 96, 315, 347, 624, 805, 939, 1153 |
| BstDSI | CCRYGG | 1 cut(s) | 128 |
| BstEII | GGTNACC | 2 cut(s) | 122, 1324 |
| BstF5I | GGATG | 6 cut(s) | 88, 302, 497, 742, 949, 1073 |
| BstH2I | RGCGCY | 1 cut(s) | 592 |
| BstHHI | GCGC | 1 cut(s) | 591 |
| BstKTI | GATC | 4 cut(s) | 181, 290, 565, 1022 |
| BstMAI | GTCTC | 2 cut(s) | 127, 1349 |
| BstMBI | GATC | 4 cut(s) | 178, 287, 562, 1019 |
| BstMWI | GCNNNNNNNGC | 3 cut(s) | 217, 398, 595 |
| BstNI | CCWGG | 2 cut(s) | 120, 294 |
| BstNSI | RCATGY | 3 cut(s) | 211, 973, 1186 |
| BstPI | GGTNACC | 2 cut(s) | 122, 1324 |
| BstSCI | CCNGG | 2 cut(s) | 118, 292 |
| BstSFI | CTRYAG | 1 cut(s) | 417 |
| BstV1I | GCAGC | 5 cut(s) | 376, 860, 946, 1009, 1381 |
| BstX2I | RGATCY | 2 cut(s) | 178, 287 |
| BstXI | CCANNNNNNTGG | 1 cut(s) | 83 |
| BstYI | RGATCY | 2 cut(s) | 178, 287 |
| Bsu36I | CCTNAGG | 1 cut(s) | 939 |
| BtgI | CCRYGG | 1 cut(s) | 128 |
| BtgZI | GCGATG | 1 cut(s) | 707 |
| BtsCI | GGATG | 6 cut(s) | 88, 302, 497, 742, 949, 1073 |
| BtsIMutI | CAGTG | 2 cut(s) | 93, 289 |
| Cac8I | GCNNGC | 5 cut(s) | 43, 55, 971, 975, 1188 |
| CaiI | CAGNNNCTG | 2 cut(s) | 623, 1003 |
| CfoI | GCGC | 1 cut(s) | 591 |
| Cfr13I | GGNCC | 2 cut(s) | 296, 859 |
| Csp6I | GTAC | 3 cut(s) | 411, 707, 1314 |
| CspCI | CAANNNNNGTGG | 2 cut(s) | 265, 300 |
| CviAII | CATG | 9 cut(s) | 129, 208, 545, 720, 970, 1078, 1183, 1310, 1406 |
| CviQI | GTAC | 3 cut(s) | 411, 707, 1314 |
| DdeI | CTNAG | 8 cut(s) | 27, 96, 315, 347, 624, 805, 939, 1153 |
| DinI | GGCGCC | 1 cut(s) | 590 |
| DpnI | GATC | 4 cut(s) | 180, 289, 564, 1021 |
| DpnII | GATC | 4 cut(s) | 178, 287, 562, 1019 |
| DraI | TTTAAA | 1 cut(s) | 273 |
| DraIII | CACNNNGTG | 1 cut(s) | 1239 |
| Eam1104I | CTCTTC | 2 cut(s) | 465, 1047 |
| EarI | CTCTTC | 2 cut(s) | 465, 1047 |
| EciI | GGCGGA | 1 cut(s) | 40 |
| Eco130I | CCWWGG | 2 cut(s) | 128, 1140 |
| Eco47I | GGWCC | 2 cut(s) | 296, 859 |
| Eco57I | CTGAAG | 3 cut(s) | 357, 506, 1416 |
| Eco81I | CCTNAGG | 1 cut(s) | 939 |
| Eco91I | GGTNACC | 2 cut(s) | 122, 1324 |
| EcoO109I | RGGNCCY | 1 cut(s) | 296 |
| EcoO65I | GGTNACC | 2 cut(s) | 122, 1324 |
| EcoRI | GAATTC | 2 cut(s) | 888, 1246 |
| EcoRII | CCWGG | 2 cut(s) | 118, 292 |
| EcoT14I | CCWWGG | 2 cut(s) | 128, 1140 |
| EcoT22I | ATGCAT | 1 cut(s) | 546 |
| EgeI | GGCGCC | 1 cut(s) | 590 |
| EheI | GGCGCC | 1 cut(s) | 590 |
| ErhI | CCWWGG | 2 cut(s) | 128, 1140 |
| Esp3I | CGTCTC | 1 cut(s) | 127 |
| FaeI | CATG | 9 cut(s) | 132, 211, 548, 723, 973, 1081, 1186, 1313, 1409 |
| FaqI | GGGAC | 3 cut(s) | 210, 282, 605 |
| FatI | CATG | 9 cut(s) | 128, 207, 544, 719, 969, 1077, 1182, 1309, 1405 |
| FauI | CCCGC | 1 cut(s) | 190 |
| Fnu4HI | GCNGC | 6 cut(s) | 390, 849, 935, 998, 1370, 1411 |
| FokI | GGATG | 6 cut(s) | 95, 289, 484, 749, 956, 1060 |
| Fsp4HI | GCNGC | 6 cut(s) | 390, 849, 935, 998, 1370, 1411 |
| FspBI | CTAG | 6 cut(s) | 267, 404, 447, 480, 653, 924 |
| GlaI | GCGC | 1 cut(s) | 590 |
| GluI | GCNGC | 6 cut(s) | 390, 849, 935, 998, 1370, 1411 |
| GsaI | CCCAGC | 2 cut(s) | 264, 1333 |
| HaeII | RGCGCY | 1 cut(s) | 592 |
| HapII | CCGG | 1 cut(s) | 1319 |
| HhaI | GCGC | 1 cut(s) | 591 |
| Hin1I | GRCGYC | 1 cut(s) | 589 |
| Hin1II | CATG | 9 cut(s) | 132, 211, 548, 723, 973, 1081, 1186, 1313, 1409 |
| Hin6I | GCGC | 1 cut(s) | 589 |
| HinP1I | GCGC | 1 cut(s) | 589 |
| HincII | GTYRAC | 2 cut(s) | 64, 321 |
| HindII | GTYRAC | 2 cut(s) | 64, 321 |
| HindIII | AAGCTT | 2 cut(s) | 18, 467 |
| HinfI | GANTC | 4 cut(s) | 379, 536, 1177, 1230 |
| HpaII | CCGG | 1 cut(s) | 1319 |
| HphI | GGTGA | 5 cut(s) | 63, 116, 776, 1108, 1336 |
| Hpy166II | GTNNAC | 7 cut(s) | 64, 244, 321, 413, 611, 707, 1218 |
| Hpy188I | TCNGA | 4 cut(s) | 234, 363, 376, 384 |
| Hpy188III | TCNNGA | 6 cut(s) | 533, 837, 854, 862, 992, 1268 |
| Hpy8I | GTNNAC | 7 cut(s) | 64, 244, 321, 413, 611, 707, 1218 |
| HpyAV | CCTTC | 6 cut(s) | 78, 347, 379, 447, 727, 814 |
| HpyCH4III | ACNGT | 1 cut(s) | 172 |
| HpyCH4IV | ACGT | 2 cut(s) | 1110, 1214 |
| HpyCH4V | TGCA | 8 cut(s) | 401, 544, 723, 848, 1028, 1034, 1124, 1186 |
| HpyF10VI | GCNNNNNNNGC | 3 cut(s) | 217, 398, 595 |
| HpyF3I | CTNAG | 8 cut(s) | 27, 96, 315, 347, 624, 805, 939, 1153 |
| HpySE526I | ACGT | 2 cut(s) | 1110, 1214 |
| Hsp92I | GRCGYC | 1 cut(s) | 589 |
| Hsp92II | CATG | 9 cut(s) | 132, 211, 548, 723, 973, 1081, 1186, 1313, 1409 |
| HspAI | GCGC | 1 cut(s) | 589 |
| KasI | GGCGCC | 1 cut(s) | 588 |
| Kzo9I | GATC | 4 cut(s) | 178, 287, 562, 1019 |
| Lsp1109I | GCAGC | 5 cut(s) | 376, 860, 946, 1009, 1381 |
| LweI | GCATC | 2 cut(s) | 28, 1082 |
| MaeI | CTAG | 6 cut(s) | 267, 404, 447, 480, 653, 924 |
| MaeII | ACGT | 2 cut(s) | 1110, 1214 |
| MaeIII | GTNAC | 5 cut(s) | 122, 568, 874, 1231, 1324 |
| MalI | GATC | 4 cut(s) | 180, 289, 564, 1021 |
| MboI | GATC | 4 cut(s) | 178, 287, 562, 1019 |
| MfeI | CAATTG | 2 cut(s) | 516, 1029 |
| MflI | RGATCY | 2 cut(s) | 178, 287 |
| MhlI | GDGCHC | 1 cut(s) | 931 |
| Mly113I | GGCGCC | 1 cut(s) | 589 |
| MlyI | GAGTC | 2 cut(s) | 545, 1239 |
| Mph1103I | ATGCAT | 1 cut(s) | 546 |
| MroXI | GAANNNNTTC | 1 cut(s) | 1401 |
| MseI | TTAA | 3 cut(s) | 272, 473, 630 |
| MslI | CAYNNNNRTG | 1 cut(s) | 1094 |
| MspA1I | CMGCKG | 1 cut(s) | 1413 |
| MspI | CCGG | 1 cut(s) | 1319 |
| MspR9I | CCNGG | 2 cut(s) | 120, 294 |
| MssI | GTTTAAAC | 1 cut(s) | 273 |
| MunI | CAATTG | 2 cut(s) | 516, 1029 |
| Mva1269I | GAATGC | 1 cut(s) | 850 |
| MvaI | CCWGG | 2 cut(s) | 120, 294 |
| MwoI | GCNNNNNNNGC | 3 cut(s) | 217, 398, 595 |
| NarI | GGCGCC | 1 cut(s) | 589 |
| NcoI | CCATGG | 1 cut(s) | 128 |
| NdeII | GATC | 4 cut(s) | 178, 287, 562, 1019 |
| NlaIII | CATG | 9 cut(s) | 132, 211, 548, 723, 973, 1081, 1186, 1313, 1409 |
| NlaIV | GGNNCC | 4 cut(s) | 180, 289, 298, 590 |
| NmeAIII | GCCGAG | 1 cut(s) | 1345 |
| NmuCI | GTSAC | 4 cut(s) | 122, 874, 1231, 1324 |
| NsiI | ATGCAT | 1 cut(s) | 546 |
| NspI | RCATGY | 3 cut(s) | 211, 973, 1186 |
| OliI | CACNNNNGTG | 1 cut(s) | 1094 |
| PaeI | GCATGC | 1 cut(s) | 973 |
| PctI | GAATGC | 1 cut(s) | 850 |
| PdmI | GAANNNNTTC | 1 cut(s) | 1401 |
| PfeI | GAWTC | 2 cut(s) | 379, 1177 |
| PkrI | GCNGC | 6 cut(s) | 391, 850, 936, 999, 1371, 1412 |
| PleI | GAGTC | 2 cut(s) | 544, 1238 |
| PluTI | GGCGCC | 1 cut(s) | 592 |
| PmeI | GTTTAAAC | 1 cut(s) | 273 |
| PpsI | GAGTC | 2 cut(s) | 544, 1238 |
| PpuMI | RGGWCCY | 1 cut(s) | 296 |
| Psp5II | RGGWCCY | 1 cut(s) | 296 |
| Psp6I | CCWGG | 2 cut(s) | 118, 292 |
| PspEI | GGTNACC | 2 cut(s) | 122, 1324 |
| PspFI | CCCAGC | 2 cut(s) | 260, 1329 |
| PspGI | CCWGG | 2 cut(s) | 118, 292 |
| PspN4I | GGNNCC | 4 cut(s) | 180, 289, 298, 590 |
| PspPI | GGNCC | 2 cut(s) | 296, 859 |
| PspPPI | RGGWCCY | 1 cut(s) | 296 |
| PstNI | CAGNNNCTG | 2 cut(s) | 623, 1003 |
| PsuI | RGATCY | 2 cut(s) | 178, 287 |
| PvuII | CAGCTG | 1 cut(s) | 1413 |
| RsaI | GTAC | 3 cut(s) | 412, 708, 1315 |
| RsaNI | GTAC | 3 cut(s) | 411, 707, 1314 |
| RseI | CAYNNNNRTG | 1 cut(s) | 1094 |
| SaqAI | TTAA | 3 cut(s) | 272, 473, 630 |
| SatI | GCNGC | 6 cut(s) | 390, 849, 935, 998, 1370, 1411 |
| Sau3AI | GATC | 4 cut(s) | 178, 287, 562, 1019 |
| Sau96I | GGNCC | 2 cut(s) | 296, 859 |
| SchI | GAGTC | 2 cut(s) | 545, 1239 |
| ScrFI | CCNGG | 2 cut(s) | 120, 294 |
| SduI | GDGCHC | 1 cut(s) | 931 |
| SfaNI | GCATC | 2 cut(s) | 28, 1082 |
| SfcI | CTRYAG | 1 cut(s) | 417 |
| SfoI | GGCGCC | 1 cut(s) | 590 |
| SinI | GGWCC | 2 cut(s) | 296, 859 |
| SmiMI | CAYNNNNRTG | 1 cut(s) | 1094 |
| SmlI | CTYRAG | 3 cut(s) | 835, 852, 992 |
| SmoI | CTYRAG | 3 cut(s) | 835, 852, 992 |
| SphI | GCATGC | 1 cut(s) | 973 |
| SsiI | CCGC | 3 cut(s) | 51, 183, 1322 |
| SspDI | GGCGCC | 1 cut(s) | 588 |
| SspMI | CTAG | 6 cut(s) | 267, 404, 447, 480, 653, 924 |
| StyD4I | CCNGG | 2 cut(s) | 118, 292 |
| StyI | CCWWGG | 2 cut(s) | 128, 1140 |
| TaaI | ACNGT | 1 cut(s) | 172 |
| TaiI | ACGT | 2 cut(s) | 1113, 1217 |
| TaqI | TCGA | 2 cut(s) | 667, 796 |
| TaqII | GACCGA | 1 cut(s) | 1284 |
| TfiI | GAWTC | 2 cut(s) | 379, 1177 |
| Tru1I | TTAA | 3 cut(s) | 272, 473, 630 |
| Tru9I | TTAA | 3 cut(s) | 272, 473, 630 |
| TscAI | CASTG | 2 cut(s) | 100, 289 |
| TseFI | GTSAC | 4 cut(s) | 122, 874, 1231, 1324 |
| TseI | GCWGC | 6 cut(s) | 389, 848, 934, 997, 1369, 1410 |
| Tsp45I | GTSAC | 4 cut(s) | 122, 874, 1231, 1324 |
| TspDTI | ATGAA | 5 cut(s) | 593, 708, 1161, 1394, 1395 |
| TspRI | CASTG | 2 cut(s) | 100, 289 |
| VpaK11BI | GGWCC | 2 cut(s) | 296, 859 |
| XapI | RAATTY | 4 cut(s) | 798, 888, 1246, 1383 |
| XceI | RCATGY | 3 cut(s) | 211, 973, 1186 |
| XmnI | GAANNNNTTC | 1 cut(s) | 1401 |
| XspI | CTAG | 6 cut(s) | 267, 404, 447, 480, 653, 924 |
| Zsp2I | ATGCAT | 1 cut(s) | 546 |