The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins. Some of these proteins have been shown both in vivo and in vitro to have ubiquitin E3 ligase activity.
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| Species | Orthologous Gene IDs |
|---|---|
| arabidopsis_thaliana | AT2G22120 AT2G22120 |
| fragaria_vesca | FvH4_1g21840 FvH4_1g21840 |
| malus_domestica | MD01G1021800.v1.1 MD15G1330300.v1.1 |
| prunus_persica | Prupe.6G177400_v2.0.a1 |
| pyrus_communis | pycom01g04990 pycom15g29490 |
| rosa_chinensis | RchiOBHm_Chr2g0115731 |
| rosa_laevigata | RLG00000018204 |
| rosa_multiflora | Rmu_ssc0000197.1_g000058 |
| rosa_roxburghii | Rroxscaffold_2G00127920 Rroxscaffold_2G00128780 |
| rosa_rugosa | Rorug02G0199700 Rorug02G0199700 |
| rosa_samantha | Rh2AG256800 Rh2BG267400 Rh2CG262400 Rh2DG265200 |
| rosa_wichuraiana | Rw2G020100 |
| Enzyme | Recognition Site | Cut Count | Positions (bp) |
|---|---|---|---|
| AanI | TTATAA | 1 cut(s) | 731 |
| AarI | CACCTGC | 1 cut(s) | 665 |
| AbsI | CCTCGAGG | 1 cut(s) | 71 |
| Acc16I | TGCGCA | 2 cut(s) | 536, 598 |
| Acc36I | ACCTGC | 2 cut(s) | 248, 665 |
| AccB7I | CCANNNNNTGG | 1 cut(s) | 651 |
| AciI | CCGC | 3 cut(s) | 77, 465, 823 |
| AclWI | GGATC | 2 cut(s) | 198, 907 |
| AcoI | YGGCCR | 2 cut(s) | 3, 345 |
| AcsI | RAATTY | 2 cut(s) | 105, 302 |
| AfaI | GTAC | 3 cut(s) | 235, 643, 747 |
| AfeI | AGCGCT | 1 cut(s) | 954 |
| AfiI | CCNNNNNNNGG | 3 cut(s) | 76, 651, 768 |
| AgsI | TTSAA | 2 cut(s) | 116, 301 |
| AjnI | CCWGG | 4 cut(s) | 82, 586, 613, 786 |
| AluBI | AGCT | 6 cut(s) | 203, 355, 445, 470, 794, 946 |
| AluI | AGCT | 6 cut(s) | 203, 355, 445, 470, 794, 946 |
| AlwI | GGATC | 2 cut(s) | 198, 907 |
| AlwNI | CAGNNNCTG | 2 cut(s) | 902, 946 |
| Ama87I | CYCGRG | 1 cut(s) | 71 |
| Aor51HI | AGCGCT | 1 cut(s) | 954 |
| AoxI | GGCC | 5 cut(s) | 3, 79, 345, 372, 958 |
| ApaI | GGGCCC | 1 cut(s) | 83 |
| ApeKI | GCWGC | 3 cut(s) | 504, 820, 943 |
| ApoI | RAATTY | 2 cut(s) | 105, 302 |
| ArsI | GACNNNNNNTTYG | 2 cut(s) | 798, 830 |
| AspLEI | GCGC | 4 cut(s) | 537, 599, 701, 955 |
| AspS9I | GGNCC | 2 cut(s) | 79, 80 |
| AsuC2I | CCSGG | 1 cut(s) | 179 |
| AsuHPI | GGTGA | 4 cut(s) | 40, 689, 716, 899 |
| AvaI | CYCGRG | 1 cut(s) | 71 |
| BaeGI | GKGCMC | 1 cut(s) | 83 |
| BanII | GRGCYC | 1 cut(s) | 83 |
| BarI | GAAGNNNNNNTAC | 2 cut(s) | 699, 731 |
| BbvI | GCAGC | 3 cut(s) | 491, 832, 955 |
| BccI | CCATC | 3 cut(s) | 116, 389, 878 |
| BceAI | ACGGC | 1 cut(s) | 332 |
| BciT130I | CCWGG | 4 cut(s) | 84, 588, 615, 788 |
| BcnI | CCSGG | 1 cut(s) | 179 |
| BfaI | CTAG | 1 cut(s) | 57 |
| BfmI | CTRYAG | 1 cut(s) | 778 |
| BfoI | RGCGCY | 2 cut(s) | 702, 956 |
| BfuAI | ACCTGC | 2 cut(s) | 248, 665 |
| BglI | GCCNNNNNGGC | 1 cut(s) | 380 |
| BisI | GCNGC | 4 cut(s) | 505, 821, 824, 944 |
| BlpI | GCTNAGC | 1 cut(s) | 549 |
| BlsI | GCNGC | 4 cut(s) | 506, 822, 825, 945 |
| Bme1390I | CCNGG | 5 cut(s) | 84, 179, 588, 615, 788 |
| BmeT110I | CYCGRG | 1 cut(s) | 71 |
| BmgT120I | GGNCC | 2 cut(s) | 79, 80 |
| BmiI | GGNNCC | 2 cut(s) | 81, 249 |
| BmrFI | CCNGG | 5 cut(s) | 84, 179, 588, 615, 788 |
| BmrI | ACTGGG | 1 cut(s) | 758 |
| BmsI | GCATC | 1 cut(s) | 840 |
| BmuI | ACTGGG | 1 cut(s) | 758 |
| Bpu10I | CCTNAGC | 1 cut(s) | 930 |
| Bpu1102I | GCTNAGC | 1 cut(s) | 549 |
| BpuEI | CTTGAG | 1 cut(s) | 280 |
| BpuMI | CCSGG | 1 cut(s) | 179 |
| BsaJI | CCNNGG | 1 cut(s) | 82 |
| Bsc4I | CCNNNNNNNGG | 3 cut(s) | 76, 651, 768 |
| Bse1I | ACTGG | 2 cut(s) | 97, 753 |
| Bse3DI | GCAATG | 2 cut(s) | 135, 544 |
| BseBI | CCWGG | 4 cut(s) | 84, 588, 615, 788 |
| BseDI | CCNNGG | 1 cut(s) | 82 |
| BseGI | GGATG | 3 cut(s) | 30, 855, 883 |
| BseLI | CCNNNNNNNGG | 3 cut(s) | 76, 651, 768 |
| BseMI | GCAATG | 2 cut(s) | 135, 544 |
| BseMII | CTCAG | 3 cut(s) | 27, 563, 921 |
| BseNI | ACTGG | 2 cut(s) | 97, 753 |
| BseRI | GAGGAG | 1 cut(s) | 909 |
| BseSI | GKGCMC | 1 cut(s) | 83 |
| BseXI | GCAGC | 3 cut(s) | 491, 832, 955 |
| BseYI | CCCAGC | 1 cut(s) | 651 |
| BshFI | GGCC | 5 cut(s) | 5, 81, 347, 374, 960 |
| BsiHKCI | CYCGRG | 1 cut(s) | 71 |
| BsiSI | CCGG | 1 cut(s) | 178 |
| BslFI | GGGAC | 4 cut(s) | 143, 172, 338, 765 |
| BslI | CCNNNNNNNGG | 3 cut(s) | 76, 651, 768 |
| BsmFI | GGGAC | 4 cut(s) | 143, 172, 338, 765 |
| BsnI | GGCC | 5 cut(s) | 5, 81, 347, 374, 960 |
| BsoBI | CYCGRG | 1 cut(s) | 71 |
| Bsp120I | GGGCCC | 1 cut(s) | 79 |
| Bsp1286I | GDGCHC | 1 cut(s) | 83 |
| Bsp1407I | TGTACA | 1 cut(s) | 233 |
| Bsp143I | GATC | 5 cut(s) | 7, 45, 63, 190, 899 |
| Bsp1720I | GCTNAGC | 1 cut(s) | 549 |
| BspACI | CCGC | 3 cut(s) | 77, 465, 823 |
| BspANI | GGCC | 5 cut(s) | 5, 81, 347, 374, 960 |
| BspCNI | CTCAG | 3 cut(s) | 26, 562, 922 |
| BspLI | GGNNCC | 2 cut(s) | 81, 249 |
| BspMI | ACCTGC | 2 cut(s) | 248, 665 |
| BspPI | GGATC | 2 cut(s) | 198, 907 |
| BsrDI | GCAATG | 2 cut(s) | 135, 544 |
| BsrGI | TGTACA | 1 cut(s) | 233 |
| BsrI | ACTGG | 2 cut(s) | 97, 753 |
| BssECI | CCNNGG | 1 cut(s) | 82 |
| BssMI | GATC | 5 cut(s) | 7, 45, 63, 190, 899 |
| Bst2UI | CCWGG | 4 cut(s) | 84, 588, 615, 788 |
| Bst4CI | ACNGT | 6 cut(s) | 440, 527, 605, 641, 763, 782 |
| BstAUI | TGTACA | 1 cut(s) | 233 |
| BstC8I | GCNNGC | 1 cut(s) | 79 |
| BstDEI | CTNAG | 4 cut(s) | 13, 446, 549, 930 |
| BstF5I | GGATG | 3 cut(s) | 30, 855, 883 |
| BstH2I | RGCGCY | 2 cut(s) | 702, 956 |
| BstHHI | GCGC | 4 cut(s) | 537, 599, 701, 955 |
| BstKTI | GATC | 5 cut(s) | 10, 48, 66, 193, 902 |
| BstMBI | GATC | 5 cut(s) | 7, 45, 63, 190, 899 |
| BstMWI | GCNNNNNNNGC | 9 cut(s) | 108, 380, 412, 576, 671, 696, 707, 940, 952 |
| BstNI | CCWGG | 4 cut(s) | 84, 588, 615, 788 |
| BstNSI | RCATGY | 1 cut(s) | 651 |
| BstSCI | CCNGG | 5 cut(s) | 82, 177, 586, 613, 786 |
| BstSFI | CTRYAG | 1 cut(s) | 778 |
| BstSLI | GKGCMC | 1 cut(s) | 83 |
| BstV1I | GCAGC | 3 cut(s) | 491, 832, 955 |
| BstX2I | RGATCY | 1 cut(s) | 899 |
| BstYI | RGATCY | 1 cut(s) | 899 |
| BsuRI | GGCC | 5 cut(s) | 5, 81, 347, 374, 960 |
| BtsCI | GGATG | 3 cut(s) | 30, 855, 883 |
| BtsIMutI | CAGTG | 3 cut(s) | 104, 445, 787 |
| BveI | ACCTGC | 2 cut(s) | 248, 665 |
| Cac8I | GCNNGC | 1 cut(s) | 79 |
| CaiI | CAGNNNCTG | 2 cut(s) | 902, 946 |
| CfoI | GCGC | 4 cut(s) | 537, 599, 701, 955 |
| Cfr13I | GGNCC | 2 cut(s) | 79, 80 |
| CseI | GACGC | 1 cut(s) | 26 |
| Csp6I | GTAC | 3 cut(s) | 234, 642, 746 |
| CviAII | CATG | 4 cut(s) | 269, 426, 555, 648 |
| CviQI | GTAC | 3 cut(s) | 234, 642, 746 |
| DdeI | CTNAG | 4 cut(s) | 13, 446, 549, 930 |
| DpnI | GATC | 5 cut(s) | 9, 47, 65, 192, 901 |
| DpnII | GATC | 5 cut(s) | 7, 45, 63, 190, 899 |
| EaeI | YGGCCR | 2 cut(s) | 3, 345 |
| Eco24I | GRGCYC | 1 cut(s) | 83 |
| Eco47III | AGCGCT | 1 cut(s) | 954 |
| Eco88I | CYCGRG | 1 cut(s) | 71 |
| EcoO109I | RGGNCCY | 1 cut(s) | 80 |
| EcoRII | CCWGG | 4 cut(s) | 82, 586, 613, 786 |
| EcoT38I | GRGCYC | 1 cut(s) | 83 |
| FaeI | CATG | 4 cut(s) | 272, 429, 558, 651 |
| FaqI | GGGAC | 4 cut(s) | 143, 172, 338, 765 |
| FatI | CATG | 4 cut(s) | 268, 425, 554, 647 |
| FauI | CCCGC | 1 cut(s) | 70 |
| Fnu4HI | GCNGC | 4 cut(s) | 505, 821, 824, 944 |
| FokI | GGATG | 3 cut(s) | 17, 862, 890 |
| FriOI | GRGCYC | 1 cut(s) | 83 |
| Fsp4HI | GCNGC | 4 cut(s) | 505, 821, 824, 944 |
| FspBI | CTAG | 1 cut(s) | 57 |
| FspI | TGCGCA | 2 cut(s) | 536, 598 |
| GlaI | GCGC | 4 cut(s) | 536, 598, 700, 954 |
| GluI | GCNGC | 4 cut(s) | 505, 821, 824, 944 |
| GsaI | CCCAGC | 1 cut(s) | 655 |
| HaeII | RGCGCY | 2 cut(s) | 702, 956 |
| HaeIII | GGCC | 5 cut(s) | 5, 81, 347, 374, 960 |
| HapII | CCGG | 1 cut(s) | 178 |
| HgaI | GACGC | 1 cut(s) | 26 |
| HhaI | GCGC | 4 cut(s) | 537, 599, 701, 955 |
| Hin1II | CATG | 4 cut(s) | 272, 429, 558, 651 |
| Hin6I | GCGC | 4 cut(s) | 535, 597, 699, 953 |
| HinP1I | GCGC | 4 cut(s) | 535, 597, 699, 953 |
| HinfI | GANTC | 1 cut(s) | 309 |
| HpaII | CCGG | 1 cut(s) | 178 |
| HphI | GGTGA | 4 cut(s) | 40, 689, 716, 899 |
| Hpy166II | GTNNAC | 2 cut(s) | 175, 633 |
| Hpy188I | TCNGA | 5 cut(s) | 16, 39, 308, 741, 904 |
| Hpy188III | TCNNGA | 1 cut(s) | 560 |
| Hpy8I | GTNNAC | 2 cut(s) | 175, 633 |
| HpyAV | CCTTC | 1 cut(s) | 206 |
| HpyCH4III | ACNGT | 6 cut(s) | 440, 527, 605, 641, 763, 782 |
| HpyCH4V | TGCA | 7 cut(s) | 147, 153, 221, 243, 425, 665, 842 |
| HpyF10VI | GCNNNNNNNGC | 9 cut(s) | 108, 380, 412, 576, 671, 696, 707, 940, 952 |
| HpyF3I | CTNAG | 4 cut(s) | 13, 446, 549, 930 |
| Hsp92II | CATG | 4 cut(s) | 272, 429, 558, 651 |
| HspAI | GCGC | 4 cut(s) | 535, 597, 699, 953 |
| Kzo9I | GATC | 5 cut(s) | 7, 45, 63, 190, 899 |
| LmnI | GCTCC | 3 cut(s) | 145, 253, 467 |
| Lsp1109I | GCAGC | 3 cut(s) | 491, 832, 955 |
| LweI | GCATC | 1 cut(s) | 840 |
| MaeI | CTAG | 1 cut(s) | 57 |
| MaeIII | GTNAC | 1 cut(s) | 316 |
| MalI | GATC | 5 cut(s) | 9, 47, 65, 192, 901 |
| MboI | GATC | 5 cut(s) | 7, 45, 63, 190, 899 |
| MflI | RGATCY | 1 cut(s) | 899 |
| MhlI | GDGCHC | 1 cut(s) | 83 |
| MluCI | AATT | 4 cut(s) | 105, 302, 407, 563 |
| MmeI | TCCRAC | 1 cut(s) | 784 |
| MnlI | CCTC | 9 cut(s) | 36, 45, 67, 80, 315, 689, 868, 927, 930 |
| MseI | TTAA | 1 cut(s) | 389 |
| MspA1I | CMGCKG | 2 cut(s) | 823, 946 |
| MspI | CCGG | 1 cut(s) | 178 |
| MspR9I | CCNGG | 5 cut(s) | 84, 179, 588, 615, 788 |
| MvaI | CCWGG | 4 cut(s) | 84, 588, 615, 788 |
| MwoI | GCNNNNNNNGC | 9 cut(s) | 108, 380, 412, 576, 671, 696, 707, 940, 952 |
| NciI | CCSGG | 1 cut(s) | 179 |
| NdeII | GATC | 5 cut(s) | 7, 45, 63, 190, 899 |
| NlaIII | CATG | 4 cut(s) | 272, 429, 558, 651 |
| NlaIV | GGNNCC | 2 cut(s) | 81, 249 |
| NmeAIII | GCCGAG | 1 cut(s) | 936 |
| NmuCI | GTSAC | 1 cut(s) | 316 |
| NsbI | TGCGCA | 2 cut(s) | 536, 598 |
| NspI | RCATGY | 1 cut(s) | 651 |
| PaeR7I | CTCGAG | 1 cut(s) | 71 |
| PaqCI | CACCTGC | 1 cut(s) | 665 |
| PfeI | GAWTC | 1 cut(s) | 309 |
| PflMI | CCANNNNNTGG | 1 cut(s) | 651 |
| PkrI | GCNGC | 4 cut(s) | 506, 822, 825, 945 |
| PsiI | TTATAA | 1 cut(s) | 731 |
| Psp6I | CCWGG | 4 cut(s) | 82, 586, 613, 786 |
| PspFI | CCCAGC | 1 cut(s) | 651 |
| PspGI | CCWGG | 4 cut(s) | 82, 586, 613, 786 |
| PspN4I | GGNNCC | 2 cut(s) | 81, 249 |
| PspOMI | GGGCCC | 1 cut(s) | 79 |
| PspPI | GGNCC | 2 cut(s) | 79, 80 |
| PspXI | VCTCGAGB | 1 cut(s) | 71 |
| PstNI | CAGNNNCTG | 2 cut(s) | 902, 946 |
| PsuI | RGATCY | 1 cut(s) | 899 |
| PvuII | CAGCTG | 1 cut(s) | 946 |
| RsaI | GTAC | 3 cut(s) | 235, 643, 747 |
| RsaNI | GTAC | 3 cut(s) | 234, 642, 746 |
| SaqAI | TTAA | 1 cut(s) | 389 |
| SatI | GCNGC | 4 cut(s) | 505, 821, 824, 944 |
| Sau3AI | GATC | 5 cut(s) | 7, 45, 63, 190, 899 |
| Sau96I | GGNCC | 2 cut(s) | 79, 80 |
| ScrFI | CCNGG | 5 cut(s) | 84, 179, 588, 615, 788 |
| SduI | GDGCHC | 1 cut(s) | 83 |
| SfaNI | GCATC | 1 cut(s) | 840 |
| SfcI | CTRYAG | 1 cut(s) | 778 |
| Sfr274I | CTCGAG | 1 cut(s) | 71 |
| SlaI | CTCGAG | 1 cut(s) | 71 |
| SmlI | CTYRAG | 2 cut(s) | 71, 259 |
| SmoI | CTYRAG | 2 cut(s) | 71, 259 |
| Sse9I | AATT | 4 cut(s) | 105, 302, 407, 563 |
| SsiI | CCGC | 3 cut(s) | 77, 465, 823 |
| SspI | AATATT | 1 cut(s) | 723 |
| SspMI | CTAG | 1 cut(s) | 57 |
| StyD4I | CCNGG | 5 cut(s) | 82, 177, 586, 613, 786 |
| TaaI | ACNGT | 6 cut(s) | 440, 527, 605, 641, 763, 782 |
| TaqI | TCGA | 3 cut(s) | 66, 72, 873 |
| TasI | AATT | 4 cut(s) | 105, 302, 407, 563 |
| TatI | WGTACW | 2 cut(s) | 233, 745 |
| TauI | GCSGC | 1 cut(s) | 826 |
| TfiI | GAWTC | 1 cut(s) | 309 |
| Tru1I | TTAA | 1 cut(s) | 389 |
| Tru9I | TTAA | 1 cut(s) | 389 |
| TscAI | CASTG | 3 cut(s) | 104, 445, 787 |
| TseFI | GTSAC | 1 cut(s) | 316 |
| TseI | GCWGC | 3 cut(s) | 504, 820, 943 |
| Tsp45I | GTSAC | 1 cut(s) | 316 |
| TspDTI | ATGAA | 4 cut(s) | 124, 257, 357, 499 |
| TspGWI | ACGGA | 2 cut(s) | 132, 826 |
| TspRI | CASTG | 3 cut(s) | 104, 445, 787 |
| Van91I | CCANNNNNTGG | 1 cut(s) | 651 |
| XapI | RAATTY | 2 cut(s) | 105, 302 |
| XceI | RCATGY | 1 cut(s) | 651 |
| XhoI | CTCGAG | 1 cut(s) | 71 |
| XspI | CTAG | 1 cut(s) | 57 |