The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins. Some of these proteins have been shown both in vivo and in vitro to have ubiquitin E3 ligase activity.
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| Species | Orthologous Gene IDs |
|---|---|
| arabidopsis_thaliana | AT2G22120 AT2G22120 |
| fragaria_vesca | FvH4_1g21840 FvH4_1g21840 |
| malus_domestica | MD01G1021800.v1.1 MD15G1330300.v1.1 |
| prunus_persica | Prupe.6G177400_v2.0.a1 |
| pyrus_communis | pycom01g04990 pycom15g29490 |
| rosa_chinensis | RchiOBHm_Chr2g0115731 |
| rosa_laevigata | RLG00000018204 |
| rosa_multiflora | Rmu_ssc0000197.1_g000058 |
| rosa_roxburghii | Rroxscaffold_2G00127920 Rroxscaffold_2G00128780 |
| rosa_rugosa | Rorug02G0199700 Rorug02G0199700 |
| rosa_samantha | Rh2AG256800 Rh2BG267400 Rh2CG262400 Rh2DG265200 |
| rosa_wichuraiana | Rw2G020100 |
| Enzyme | Recognition Site | Cut Count | Positions (bp) |
|---|---|---|---|
| AanI | TTATAA | 1 cut(s) | 746 |
| AarI | CACCTGC | 1 cut(s) | 680 |
| Acc16I | TGCGCA | 2 cut(s) | 551, 613 |
| Acc36I | ACCTGC | 2 cut(s) | 263, 680 |
| AciI | CCGC | 3 cut(s) | 60, 88, 838 |
| AclWI | GGATC | 2 cut(s) | 213, 922 |
| AcoI | YGGCCR | 1 cut(s) | 3 |
| AcsI | RAATTY | 2 cut(s) | 116, 317 |
| AfaI | GTAC | 2 cut(s) | 310, 658 |
| AfiI | CCNNNNNNNGG | 2 cut(s) | 87, 783 |
| AgsI | TTSAA | 3 cut(s) | 127, 316, 368 |
| AjnI | CCWGG | 3 cut(s) | 93, 601, 628 |
| AluBI | AGCT | 7 cut(s) | 218, 460, 465, 485, 809, 944, 961 |
| AluI | AGCT | 7 cut(s) | 218, 460, 465, 485, 809, 944, 961 |
| Alw21I | GWGCWC | 1 cut(s) | 487 |
| Alw26I | GTCTC | 1 cut(s) | 930 |
| AlwI | GGATC | 2 cut(s) | 213, 922 |
| AlwNI | CAGNNNCTG | 2 cut(s) | 917, 961 |
| AoxI | GGCC | 4 cut(s) | 3, 90, 387, 973 |
| ApaI | GGGCCC | 1 cut(s) | 94 |
| ApeKI | GCWGC | 3 cut(s) | 519, 835, 958 |
| ApoI | RAATTY | 2 cut(s) | 116, 317 |
| ArsI | GACNNNNNNTTYG | 2 cut(s) | 813, 845 |
| AspLEI | GCGC | 4 cut(s) | 65, 552, 614, 716 |
| AspS9I | GGNCC | 2 cut(s) | 90, 91 |
| AsuC2I | CCSGG | 1 cut(s) | 194 |
| AsuHPI | GGTGA | 5 cut(s) | 40, 704, 731, 766, 914 |
| BaeGI | GKGCMC | 1 cut(s) | 94 |
| BanII | GRGCYC | 3 cut(s) | 57, 94, 487 |
| BarI | GAAGNNNNNNTAC | 2 cut(s) | 714, 746 |
| Bbv12I | GWGCWC | 1 cut(s) | 487 |
| BbvI | GCAGC | 3 cut(s) | 506, 847, 970 |
| BccI | CCATC | 1 cut(s) | 893 |
| BciT130I | CCWGG | 3 cut(s) | 95, 603, 630 |
| BcnI | CCSGG | 1 cut(s) | 194 |
| BcoDI | GTCTC | 1 cut(s) | 930 |
| BfmI | CTRYAG | 2 cut(s) | 793, 980 |
| BfoI | RGCGCY | 2 cut(s) | 66, 717 |
| BfuAI | ACCTGC | 2 cut(s) | 263, 680 |
| BisI | GCNGC | 5 cut(s) | 61, 520, 836, 839, 959 |
| BlpI | GCTNAGC | 3 cut(s) | 461, 564, 945 |
| BlsI | GCNGC | 5 cut(s) | 62, 521, 837, 840, 960 |
| Bme1390I | CCNGG | 4 cut(s) | 95, 194, 603, 630 |
| BmgT120I | GGNCC | 2 cut(s) | 90, 91 |
| BmiI | GGNNCC | 2 cut(s) | 92, 264 |
| BmrFI | CCNGG | 4 cut(s) | 95, 194, 603, 630 |
| BmsI | GCATC | 2 cut(s) | 400, 855 |
| Bpu1102I | GCTNAGC | 3 cut(s) | 461, 564, 945 |
| BpuMI | CCSGG | 1 cut(s) | 194 |
| BsaI | GGTCTC | 1 cut(s) | 930 |
| BsaJI | CCNNGG | 1 cut(s) | 93 |
| Bsc4I | CCNNNNNNNGG | 2 cut(s) | 87, 783 |
| Bse1I | ACTGG | 1 cut(s) | 108 |
| Bse3DI | GCAATG | 3 cut(s) | 150, 244, 288 |
| BseBI | CCWGG | 3 cut(s) | 95, 603, 630 |
| BseDI | CCNNGG | 1 cut(s) | 93 |
| BseGI | GGATG | 2 cut(s) | 870, 898 |
| BseLI | CCNNNNNNNGG | 2 cut(s) | 87, 783 |
| BseMI | GCAATG | 3 cut(s) | 150, 244, 288 |
| BseMII | CTCAG | 3 cut(s) | 27, 578, 936 |
| BseNI | ACTGG | 1 cut(s) | 108 |
| BseSI | GKGCMC | 1 cut(s) | 94 |
| BseXI | GCAGC | 3 cut(s) | 506, 847, 970 |
| BseYI | CCCAGC | 4 cut(s) | 56, 666, 763, 940 |
| Bsh1285I | CGRYCG | 1 cut(s) | 541 |
| BshFI | GGCC | 4 cut(s) | 5, 92, 389, 975 |
| BsiEI | CGRYCG | 1 cut(s) | 541 |
| BsiHKAI | GWGCWC | 1 cut(s) | 487 |
| BsiSI | CCGG | 1 cut(s) | 193 |
| BslFI | GGGAC | 4 cut(s) | 158, 187, 353, 780 |
| BslI | CCNNNNNNNGG | 2 cut(s) | 87, 783 |
| BsmAI | GTCTC | 1 cut(s) | 930 |
| BsmFI | GGGAC | 4 cut(s) | 158, 187, 353, 780 |
| BsnI | GGCC | 4 cut(s) | 5, 92, 389, 975 |
| Bso31I | GGTCTC | 1 cut(s) | 930 |
| Bsp120I | GGGCCC | 1 cut(s) | 90 |
| Bsp1286I | GDGCHC | 3 cut(s) | 57, 94, 487 |
| Bsp143I | GATC | 5 cut(s) | 7, 45, 74, 205, 914 |
| Bsp1720I | GCTNAGC | 3 cut(s) | 461, 564, 945 |
| BspACI | CCGC | 3 cut(s) | 60, 88, 838 |
| BspANI | GGCC | 4 cut(s) | 5, 92, 389, 975 |
| BspCNI | CTCAG | 3 cut(s) | 26, 577, 937 |
| BspLI | GGNNCC | 2 cut(s) | 92, 264 |
| BspMI | ACCTGC | 2 cut(s) | 263, 680 |
| BspPI | GGATC | 2 cut(s) | 213, 922 |
| BspTNI | GGTCTC | 1 cut(s) | 930 |
| BsrDI | GCAATG | 3 cut(s) | 150, 244, 288 |
| BsrI | ACTGG | 1 cut(s) | 108 |
| BssECI | CCNNGG | 1 cut(s) | 93 |
| BssMI | GATC | 5 cut(s) | 7, 45, 74, 205, 914 |
| Bst2UI | CCWGG | 3 cut(s) | 95, 603, 630 |
| Bst4CI | ACNGT | 5 cut(s) | 455, 542, 620, 656, 778 |
| BstAPI | GCANNNNNTGC | 1 cut(s) | 255 |
| BstC8I | GCNNGC | 1 cut(s) | 90 |
| BstDEI | CTNAG | 4 cut(s) | 13, 461, 564, 945 |
| BstF5I | GGATG | 2 cut(s) | 870, 898 |
| BstH2I | RGCGCY | 2 cut(s) | 66, 717 |
| BstHHI | GCGC | 4 cut(s) | 65, 552, 614, 716 |
| BstKTI | GATC | 5 cut(s) | 10, 48, 77, 208, 917 |
| BstMAI | GTCTC | 1 cut(s) | 930 |
| BstMBI | GATC | 5 cut(s) | 7, 45, 74, 205, 914 |
| BstMCI | CGRYCG | 1 cut(s) | 541 |
| BstNI | CCWGG | 3 cut(s) | 95, 603, 630 |
| BstNSI | RCATGY | 1 cut(s) | 666 |
| BstSCI | CCNGG | 4 cut(s) | 93, 192, 601, 628 |
| BstSFI | CTRYAG | 2 cut(s) | 793, 980 |
| BstSLI | GKGCMC | 1 cut(s) | 94 |
| BstV1I | GCAGC | 3 cut(s) | 506, 847, 970 |
| BstX2I | RGATCY | 1 cut(s) | 914 |
| BstYI | RGATCY | 1 cut(s) | 914 |
| BsuRI | GGCC | 4 cut(s) | 5, 92, 389, 975 |
| BtsCI | GGATG | 2 cut(s) | 870, 898 |
| BtsIMutI | CAGTG | 2 cut(s) | 115, 460 |
| BveI | ACCTGC | 2 cut(s) | 263, 680 |
| Cac8I | GCNNGC | 1 cut(s) | 90 |
| CaiI | CAGNNNCTG | 2 cut(s) | 917, 961 |
| CfoI | GCGC | 4 cut(s) | 65, 552, 614, 716 |
| Cfr13I | GGNCC | 2 cut(s) | 90, 91 |
| CseI | GACGC | 1 cut(s) | 26 |
| CsiI | ACCWGGT | 1 cut(s) | 601 |
| Csp6I | GTAC | 2 cut(s) | 309, 657 |
| CviAII | CATG | 5 cut(s) | 31, 284, 441, 570, 663 |
| CviQI | GTAC | 2 cut(s) | 309, 657 |
| DdeI | CTNAG | 4 cut(s) | 13, 461, 564, 945 |
| DpnI | GATC | 5 cut(s) | 9, 47, 76, 207, 916 |
| DpnII | GATC | 5 cut(s) | 7, 45, 74, 205, 914 |
| EaeI | YGGCCR | 1 cut(s) | 3 |
| Ecl136II | GAGCTC | 1 cut(s) | 485 |
| Eco24I | GRGCYC | 3 cut(s) | 57, 94, 487 |
| Eco31I | GGTCTC | 1 cut(s) | 930 |
| Eco53kI | GAGCTC | 1 cut(s) | 485 |
| EcoICRI | GAGCTC | 1 cut(s) | 485 |
| EcoO109I | RGGNCCY | 1 cut(s) | 91 |
| EcoRII | CCWGG | 3 cut(s) | 93, 601, 628 |
| EcoT38I | GRGCYC | 3 cut(s) | 57, 94, 487 |
| FaeI | CATG | 5 cut(s) | 34, 287, 444, 573, 666 |
| FaqI | GGGAC | 4 cut(s) | 158, 187, 353, 780 |
| FatI | CATG | 5 cut(s) | 30, 283, 440, 569, 662 |
| FauI | CCCGC | 1 cut(s) | 81 |
| Fnu4HI | GCNGC | 5 cut(s) | 61, 520, 836, 839, 959 |
| FokI | GGATG | 2 cut(s) | 877, 905 |
| FriOI | GRGCYC | 3 cut(s) | 57, 94, 487 |
| Fsp4HI | GCNGC | 5 cut(s) | 61, 520, 836, 839, 959 |
| FspI | TGCGCA | 2 cut(s) | 551, 613 |
| GlaI | GCGC | 4 cut(s) | 64, 551, 613, 715 |
| GluI | GCNGC | 5 cut(s) | 61, 520, 836, 839, 959 |
| GsaI | CCCAGC | 4 cut(s) | 60, 670, 767, 944 |
| HaeII | RGCGCY | 2 cut(s) | 66, 717 |
| HaeIII | GGCC | 4 cut(s) | 5, 92, 389, 975 |
| HapII | CCGG | 1 cut(s) | 193 |
| HgaI | GACGC | 1 cut(s) | 26 |
| HhaI | GCGC | 4 cut(s) | 65, 552, 614, 716 |
| Hin1II | CATG | 5 cut(s) | 34, 287, 444, 573, 666 |
| Hin6I | GCGC | 4 cut(s) | 63, 550, 612, 714 |
| HinP1I | GCGC | 4 cut(s) | 63, 550, 612, 714 |
| HincII | GTYRAC | 1 cut(s) | 599 |
| HindII | GTYRAC | 1 cut(s) | 599 |
| HinfI | GANTC | 1 cut(s) | 324 |
| HpaII | CCGG | 1 cut(s) | 193 |
| HphI | GGTGA | 5 cut(s) | 40, 704, 731, 766, 914 |
| Hpy166II | GTNNAC | 3 cut(s) | 190, 599, 648 |
| Hpy188I | TCNGA | 5 cut(s) | 16, 39, 323, 756, 919 |
| Hpy188III | TCNNGA | 2 cut(s) | 331, 575 |
| Hpy8I | GTNNAC | 3 cut(s) | 190, 599, 648 |
| HpyAV | CCTTC | 1 cut(s) | 221 |
| HpyCH4III | ACNGT | 5 cut(s) | 455, 542, 620, 656, 778 |
| HpyCH4V | TGCA | 8 cut(s) | 162, 168, 236, 249, 258, 440, 680, 857 |
| HpyF3I | CTNAG | 4 cut(s) | 13, 461, 564, 945 |
| Hsp92II | CATG | 5 cut(s) | 34, 287, 444, 573, 666 |
| HspAI | GCGC | 4 cut(s) | 63, 550, 612, 714 |
| Kzo9I | GATC | 5 cut(s) | 7, 45, 74, 205, 914 |
| LmnI | GCTCC | 3 cut(s) | 160, 268, 482 |
| Lsp1109I | GCAGC | 3 cut(s) | 506, 847, 970 |
| LweI | GCATC | 2 cut(s) | 400, 855 |
| MabI | ACCWGGT | 1 cut(s) | 601 |
| MaeIII | GTNAC | 2 cut(s) | 331, 533 |
| MalI | GATC | 5 cut(s) | 9, 47, 76, 207, 916 |
| MboI | GATC | 5 cut(s) | 7, 45, 74, 205, 914 |
| MboII | GAAGA | 1 cut(s) | 319 |
| MflI | RGATCY | 1 cut(s) | 914 |
| MhlI | GDGCHC | 3 cut(s) | 57, 94, 487 |
| MluCI | AATT | 4 cut(s) | 116, 317, 422, 578 |
| MmeI | TCCRAC | 1 cut(s) | 799 |
| MnlI | CCTC | 8 cut(s) | 36, 45, 91, 330, 704, 812, 883, 945 |
| MseI | TTAA | 1 cut(s) | 404 |
| MspA1I | CMGCKG | 4 cut(s) | 60, 838, 944, 961 |
| MspI | CCGG | 1 cut(s) | 193 |
| MspR9I | CCNGG | 4 cut(s) | 95, 194, 603, 630 |
| MvaI | CCWGG | 3 cut(s) | 95, 603, 630 |
| NciI | CCSGG | 1 cut(s) | 194 |
| NdeII | GATC | 5 cut(s) | 7, 45, 74, 205, 914 |
| NlaIII | CATG | 5 cut(s) | 34, 287, 444, 573, 666 |
| NlaIV | GGNNCC | 2 cut(s) | 92, 264 |
| NmeAIII | GCCGAG | 1 cut(s) | 951 |
| NmuCI | GTSAC | 1 cut(s) | 331 |
| NsbI | TGCGCA | 2 cut(s) | 551, 613 |
| NspI | RCATGY | 1 cut(s) | 666 |
| PaqCI | CACCTGC | 1 cut(s) | 680 |
| PfeI | GAWTC | 1 cut(s) | 324 |
| PkrI | GCNGC | 5 cut(s) | 62, 521, 837, 840, 960 |
| PsiI | TTATAA | 1 cut(s) | 746 |
| Psp124BI | GAGCTC | 1 cut(s) | 487 |
| Psp6I | CCWGG | 3 cut(s) | 93, 601, 628 |
| PspFI | CCCAGC | 4 cut(s) | 56, 666, 763, 940 |
| PspGI | CCWGG | 3 cut(s) | 93, 601, 628 |
| PspN4I | GGNNCC | 2 cut(s) | 92, 264 |
| PspOMI | GGGCCC | 1 cut(s) | 90 |
| PspPI | GGNCC | 2 cut(s) | 90, 91 |
| PstNI | CAGNNNCTG | 2 cut(s) | 917, 961 |
| PsuI | RGATCY | 1 cut(s) | 914 |
| PvuII | CAGCTG | 2 cut(s) | 944, 961 |
| RsaI | GTAC | 2 cut(s) | 310, 658 |
| RsaNI | GTAC | 2 cut(s) | 309, 657 |
| SacI | GAGCTC | 1 cut(s) | 487 |
| SaqAI | TTAA | 1 cut(s) | 404 |
| SatI | GCNGC | 5 cut(s) | 61, 520, 836, 839, 959 |
| Sau3AI | GATC | 5 cut(s) | 7, 45, 74, 205, 914 |
| Sau96I | GGNCC | 2 cut(s) | 90, 91 |
| ScrFI | CCNGG | 4 cut(s) | 95, 194, 603, 630 |
| SduI | GDGCHC | 3 cut(s) | 57, 94, 487 |
| SexAI | ACCWGGT | 1 cut(s) | 601 |
| SfaNI | GCATC | 2 cut(s) | 400, 855 |
| SfcI | CTRYAG | 2 cut(s) | 793, 980 |
| Sse9I | AATT | 4 cut(s) | 116, 317, 422, 578 |
| SsiI | CCGC | 3 cut(s) | 60, 88, 838 |
| SspI | AATATT | 1 cut(s) | 738 |
| SstI | GAGCTC | 1 cut(s) | 487 |
| StyD4I | CCNGG | 4 cut(s) | 93, 192, 601, 628 |
| TaaI | ACNGT | 5 cut(s) | 455, 542, 620, 656, 778 |
| TaqI | TCGA | 2 cut(s) | 77, 83 |
| TasI | AATT | 4 cut(s) | 116, 317, 422, 578 |
| TatI | WGTACW | 1 cut(s) | 656 |
| TauI | GCSGC | 2 cut(s) | 63, 841 |
| TfiI | GAWTC | 1 cut(s) | 324 |
| Tru1I | TTAA | 1 cut(s) | 404 |
| Tru9I | TTAA | 1 cut(s) | 404 |
| TscAI | CASTG | 2 cut(s) | 115, 460 |
| TseFI | GTSAC | 1 cut(s) | 331 |
| TseI | GCWGC | 3 cut(s) | 519, 835, 958 |
| Tsp45I | GTSAC | 1 cut(s) | 331 |
| TspDTI | ATGAA | 5 cut(s) | 139, 149, 272, 340, 514 |
| TspGWI | ACGGA | 1 cut(s) | 841 |
| TspRI | CASTG | 2 cut(s) | 115, 460 |
| XapI | RAATTY | 2 cut(s) | 116, 317 |
| XceI | RCATGY | 1 cut(s) | 666 |