pycom02g22520

Presenilin enhancer-2 subunit of gamma secretase

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
pyrus_communis
Chr2
OG0010505
Physical Location & Seq
Forward (+)
20663733 .. 20665753
2021 bp
Loading structure...
UTR
Exon/CDS
Intron
N/A

Sequence Viewer

Length: 420 bp
ATGGAAGCTTCACGGAGTAACTCGGAAATTCCGAACCTGAACCCTAGCCCGAGAAGAAACCCGATTCCGATTCCGTCTGCATCGCTGAGGTGGCCCACCATAGACGGCCCGCTGGGTCTGTCAGAGGAAGAGTCAGTGAGCTACGCGCGTAGATTTTACAAGTTCGGCTTCGCTCTGCTCCCTTGGCTTTGGGCCCTCAACTGCTTCTACTTCTGGCCCGTCCTCCGCCACTCCCGCTCCTTCCCTCGCATTCACCACTATGTTTTAAGATCAGCAGTTGGATTCACGGTATTTACTGCTCTTCTCTTGTCATGGGCACTTACATTTGCTATTGGAGGGGAGCACCTTTTCGGCCATGTTTGGGATCAACTCGTTATGTACAATCTCGCTGACAGACTTGGCTTGACAGGTTGGAGCTAA

Protein Analysis

140

Amino Acids

15.98

Weight (kDa)

9.42

Isoelectric Point (pI)

70.54

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
PEN-2 PF10251 42 - 129 1.2e-28 Presenilin enhancer-2 subunit of gamma secretase
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
Loading...
Style Settings
Image
Tree File
Tip: Beautify your tree with professional tools

Download the Full Tree (.nwk) file, then upload it to any of the following tools to customize colors, fonts, annotations, clades, and branch support.

Publication-ready
iTOL Interactive Tree Of Life · Most popular EvolView Flexible annotations MEGA Desktop phylogenetics suite FigTree Desktop tree editor

Orthologous Genes (Group: OG0010505)

Species Orthologous Gene IDs
arabidopsis_thaliana AT5G09310
fragaria_vesca FvH4_2g08820 FvH4_2g08820 FvH4_2g08820 FvH4_2g08820 FvH4_2g08820 FvH4_3g04510
malus_domestica MD02G1262600.v1.1 MD07G1057500.v1.1
prunus_persica Prupe.4G271100_v2.0.a1
pyrus_communis pycom02g22520
rosa_chinensis RchiOBHm_Chr6g0264391
rosa_laevigata RLG00000014257
rosa_multiflora Rmu_sc0004470.1_g000020
rosa_roxburghii Rroxscaffold_176G00431770
rosa_rugosa Rorug06G0012000 Rorug06G0012100
rosa_samantha Rh6BG129000 Rh6CG127000 Rh6DG114500
rosa_wichuraiana Rw6G011520

Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AccBSI CCGCTC 1 cut(s) 237
AccII CGCG 2 cut(s) 146, 148
AciI CCGC 3 cut(s) 110, 226, 235
AclWI GGATC 1 cut(s) 372
AcoI YGGCCR 1 cut(s) 352
AcsI RAATTY 1 cut(s) 27
AfaI GTAC 1 cut(s) 380
AfiI CCNNNNNNNGG 1 cut(s) 361
AluBI AGCT 3 cut(s) 8, 141, 417
AluI AGCT 3 cut(s) 8, 141, 417
Alw21I GWGCWC 1 cut(s) 345
AlwI GGATC 1 cut(s) 372
Ama87I CYCGRG 1 cut(s) 49
AoxI GGCC 5 cut(s) 92, 106, 192, 215, 352
ApaI GGGCCC 1 cut(s) 196
ApoI RAATTY 1 cut(s) 27
AspLEI GCGC 1 cut(s) 148
AspS9I GGNCC 5 cut(s) 93, 107, 192, 193, 216
AsuHPI GGTGA 1 cut(s) 245
AvaI CYCGRG 1 cut(s) 49
BaeGI GKGCMC 2 cut(s) 196, 319
BanII GRGCYC 1 cut(s) 196
Bbv12I GWGCWC 1 cut(s) 345
BbvCI CCTCAGC 1 cut(s) 86
BceAI ACGGC 1 cut(s) 121
BfaI CTAG 1 cut(s) 45
BmeT110I CYCGRG 1 cut(s) 49
BmgT120I GGNCC 5 cut(s) 93, 107, 192, 193, 216
BmiI GGNNCC 1 cut(s) 194
BmsI GCATC 1 cut(s) 89
Bpu10I CCTNAGC 1 cut(s) 86
BsaJI CCNNGG 1 cut(s) 182
BsaXI ACNNNNNCTCC 2 cut(s) 221, 251
Bsc4I CCNNNNNNNGG 1 cut(s) 361
BseDI CCNNGG 1 cut(s) 182
BseLI CCNNNNNNNGG 1 cut(s) 361
BseMII CTCAG 1 cut(s) 77
BseSI GKGCMC 2 cut(s) 196, 319
BseYI CCCAGC 1 cut(s) 112
Bsh1236I CGCG 2 cut(s) 146, 148
BshFI GGCC 5 cut(s) 94, 108, 194, 217, 354
BsiHKAI GWGCWC 1 cut(s) 345
BsiHKCI CYCGRG 1 cut(s) 49
BslI CCNNNNNNNGG 1 cut(s) 361
BsmI GAATGC 1 cut(s) 249
BsnI GGCC 5 cut(s) 94, 108, 194, 217, 354
BsoBI CYCGRG 1 cut(s) 49
Bsp120I GGGCCC 1 cut(s) 192
Bsp1286I GDGCHC 3 cut(s) 196, 319, 345
Bsp1407I TGTACA 1 cut(s) 378
Bsp143I GATC 2 cut(s) 269, 364
BspACI CCGC 3 cut(s) 110, 226, 235
BspANI GGCC 5 cut(s) 94, 108, 194, 217, 354
BspCNI CTCAG 1 cut(s) 78
BspFNI CGCG 2 cut(s) 146, 148
BspLI GGNNCC 1 cut(s) 194
BspPI GGATC 1 cut(s) 372
BspQI GCTCTTC 1 cut(s) 306
BsrBI CCGCTC 1 cut(s) 237
BsrGI TGTACA 1 cut(s) 378
BssECI CCNNGG 1 cut(s) 182
BssMI GATC 2 cut(s) 269, 364
BssT1I CCWWGG 1 cut(s) 182
Bst4CI ACNGT 1 cut(s) 289
Bst6I CTCTTC 2 cut(s) 123, 306
BstAUI TGTACA 1 cut(s) 378
BstC8I GCNNGC 1 cut(s) 110
BstDEI CTNAG 1 cut(s) 86
BstFNI CGCG 2 cut(s) 146, 148
BstHHI GCGC 1 cut(s) 148
BstKTI GATC 2 cut(s) 272, 367
BstMBI GATC 2 cut(s) 269, 364
BstMWI GCNNNNNNNGC 3 cut(s) 91, 184, 234
BstSLI GKGCMC 2 cut(s) 196, 319
BstUI CGCG 2 cut(s) 146, 148
BsuRI GGCC 5 cut(s) 94, 108, 194, 217, 354
BtgZI GCGATG 1 cut(s) 66
BtsIMutI CAGTG 1 cut(s) 141
Cac8I GCNNGC 1 cut(s) 110
CfoI GCGC 1 cut(s) 148
Cfr13I GGNCC 5 cut(s) 93, 107, 192, 193, 216
Csp6I GTAC 1 cut(s) 379
CviAII CATG 2 cut(s) 312, 356
CviQI GTAC 1 cut(s) 379
DdeI CTNAG 1 cut(s) 86
DpnI GATC 2 cut(s) 271, 366
DpnII GATC 2 cut(s) 269, 364
EaeI YGGCCR 1 cut(s) 352
Eam1104I CTCTTC 2 cut(s) 123, 306
EarI CTCTTC 2 cut(s) 123, 306
EciI GGCGGA 1 cut(s) 215
Eco130I CCWWGG 1 cut(s) 182
Eco24I GRGCYC 1 cut(s) 196
Eco88I CYCGRG 1 cut(s) 49
EcoO109I RGGNCCY 1 cut(s) 193
EcoT14I CCWWGG 1 cut(s) 182
EcoT38I GRGCYC 1 cut(s) 196
ErhI CCWWGG 1 cut(s) 182
FaeI CATG 2 cut(s) 315, 359
FaiI YATR 5 cut(s) 101, 261, 313, 357, 377
FalI AAGNNNNNCTT 2 cut(s) 152, 184
FatI CATG 2 cut(s) 311, 355
FauI CCCGC 2 cut(s) 117, 242
FriOI GRGCYC 1 cut(s) 196
FspBI CTAG 1 cut(s) 45
GlaI GCGC 1 cut(s) 147
GsaI CCCAGC 1 cut(s) 116
HaeIII GGCC 5 cut(s) 94, 108, 194, 217, 354
HhaI GCGC 1 cut(s) 148
Hin1II CATG 2 cut(s) 315, 359
Hin6I GCGC 1 cut(s) 146
HinP1I GCGC 1 cut(s) 146
HindIII AAGCTT 1 cut(s) 6
HinfI GANTC 4 cut(s) 64, 70, 131, 282
HphI GGTGA 1 cut(s) 245
Hpy188I TCNGA 4 cut(s) 25, 33, 69, 124
HpyAV CCTTC 1 cut(s) 250
HpyCH4III ACNGT 1 cut(s) 289
HpyCH4V TGCA 1 cut(s) 80
HpyF10VI GCNNNNNNNGC 3 cut(s) 91, 184, 234
HpyF3I CTNAG 1 cut(s) 86
Hsp92II CATG 2 cut(s) 315, 359
HspAI GCGC 1 cut(s) 146
Kzo9I GATC 2 cut(s) 269, 364
LguI GCTCTTC 1 cut(s) 306
LmnI GCTCC 4 cut(s) 183, 242, 340, 414
LpnPI CCDG 4 cut(s) 50, 98, 199, 393
LweI GCATC 1 cut(s) 89
MaeI CTAG 1 cut(s) 45
MaeIII GTNAC 1 cut(s) 17
MalI GATC 2 cut(s) 271, 366
MbiI CCGCTC 1 cut(s) 237
MboI GATC 2 cut(s) 269, 364
MboII GAAGA 3 cut(s) 66, 140, 293
MhlI GDGCHC 3 cut(s) 196, 319, 345
MluCI AATT 1 cut(s) 27
MlyI GAGTC 1 cut(s) 140
MmeI TCCRAC 2 cut(s) 259, 392
MnlI CCTC 6 cut(s) 81, 118, 206, 233, 255, 329
MseI TTAA 1 cut(s) 266
MslI CAYNNNNRTG 1 cut(s) 258
MspA1I CMGCKG 1 cut(s) 112
Mva1269I GAATGC 1 cut(s) 249
MvnI CGCG 2 cut(s) 146, 148
MwoI GCNNNNNNNGC 3 cut(s) 91, 184, 234
NdeII GATC 2 cut(s) 269, 364
NlaIII CATG 2 cut(s) 315, 359
NlaIV GGNNCC 1 cut(s) 194
PciSI GCTCTTC 1 cut(s) 306
PcsI WCGNNNNNNNCGW 1 cut(s) 29
PctI GAATGC 1 cut(s) 249
PfeI GAWTC 3 cut(s) 64, 70, 282
PleI GAGTC 1 cut(s) 139
PpsI GAGTC 1 cut(s) 139
PspFI CCCAGC 1 cut(s) 112
PspN4I GGNNCC 1 cut(s) 194
PspOMI GGGCCC 1 cut(s) 192
PspPI GGNCC 5 cut(s) 93, 107, 192, 193, 216
RsaI GTAC 1 cut(s) 380
RsaNI GTAC 1 cut(s) 379
RseI CAYNNNNRTG 1 cut(s) 258
SapI GCTCTTC 1 cut(s) 306
SaqAI TTAA 1 cut(s) 266
Sau3AI GATC 2 cut(s) 269, 364
Sau96I GGNCC 5 cut(s) 93, 107, 192, 193, 216
SchI GAGTC 1 cut(s) 140
SduI GDGCHC 3 cut(s) 196, 319, 345
SetI ASST 7 cut(s) 10, 39, 92, 143, 348, 412, 419
SfaNI GCATC 1 cut(s) 89
SmiMI CAYNNNNRTG 1 cut(s) 258
Sse9I AATT 1 cut(s) 27
SsiI CCGC 3 cut(s) 110, 226, 235
SspMI CTAG 1 cut(s) 45
StyI CCWWGG 1 cut(s) 182
TaaI ACNGT 1 cut(s) 289
TasI AATT 1 cut(s) 27
TatI WGTACW 1 cut(s) 378
TfiI GAWTC 3 cut(s) 64, 70, 282
Tru1I TTAA 1 cut(s) 266
Tru9I TTAA 1 cut(s) 266
TscAI CASTG 1 cut(s) 141
TspGWI ACGGA 2 cut(s) 28, 63
TspRI CASTG 1 cut(s) 141
XapI RAATTY 1 cut(s) 27
XspI CTAG 1 cut(s) 45
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.