pycom10g10310

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
pyrus_communis
Chr10
OG0011671
Physical Location & Seq
Forward (+)
13611493 .. 13612254
762 bp
Loading structure...
UTR
Exon/CDS
Intron
pycom10g10310.1

Sequence Viewer

Length: 645 bp
ATGACAAAGGCATATACCCAGCATAAACTTGACCTAGACATTCCCCGCAGAAACCCTTTTATAAATCCCCGCGTCTTCAGGACCTTGACCACACATCACAAAGCCCAATACCACTCTCTAACAGCAATGGTAAACCCGATGGTTTTCTTTTACATGACGATCGGAGGCCAGCCGGCCGGCCGAATCGTGATGGAGCTCTTCGCCGACACCACCCCCCGCACCGCGGAGAACTTCAGGGCTCTCTGCACCGGCGAGAAGGGCACAGGCCGCTCCGGCAAGCCCCTCCACTACAAGGGATCCGCCTTCCACCGCGTGATCCCCGGGTTCATGTGCCAGGGAGGTGACTTCACCGCCGGAAACGGCACCGGAGGAGAGTCGATCTACGGCGCCAAGTTCGCGGACGAGAACTTCCAGAAGAAGCACACCGGACCTGGAATATTATCCATGGCCAACGCGGGTCCCGGAACCAACGGATCTCAGTTCTTCATCTGCACAGCCAAGACCGAGTGGCTCGACGGCAAGCACGTGGTATTCGGGCAGGTGATCGAGGGGCTGGATGTGGTGAAGAACATCGAGAAGGTCGGATCTGGACAGGGAAGGACCTCGAAGCAGGTGGTTGTCGCCGACTGTGGCCAGCTATCCTAG

Protein Analysis

215

Amino Acids

23.23

Weight (kDa)

9.43

Isoelectric Point (pI)

22.77

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
Pro_isomerase PF00160 50 - 211 1.1e-49 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
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Publication-ready
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Orthologous Genes (Group: OG0011671)

Species Orthologous Gene IDs
arabidopsis_thaliana AT2G16600 AT2G16600 AT2G21130 AT4G38740
fragaria_vesca FvH4_2g01940 FvH4_2g01940
malus_domestica MD10G1119700.v1.1
prunus_persica Prupe.8G161100_v2.0.a1
pyrus_communis pycom05g11090 pycom10g10310
rosa_chinensis RchiOBHm_Chr6g0245141
rosa_laevigata RLG00000015322
rosa_roxburghii Rroxscaffold_7G00215430
rosa_rugosa Rorug05G0512300
rosa_samantha Rh6AG027100 Rh6BG023000 Rh6CG021700 Rh6DG021800
rosa_wichuraiana Rw6G002290

Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AanI TTATAA 1 cut(s) 62
AarI CACCTGC 2 cut(s) 529, 601
Acc36I ACCTGC 2 cut(s) 529, 601
AccB1I GGYRCC 2 cut(s) 362, 386
AccBSI CCGCTC 1 cut(s) 270
AccII CGCG 5 cut(s) 72, 224, 312, 398, 455
AclWI GGATC 5 cut(s) 291, 304, 310, 481, 592
AcoI YGGCCR 4 cut(s) 174, 178, 447, 631
AcuI CTGAAG 2 cut(s) 61, 217
AcvI CACGTG 1 cut(s) 526
AcyI GRCGYC 1 cut(s) 387
AdeI CACNNNGTG 1 cut(s) 313
AfiI CCNNNNNNNGG 2 cut(s) 223, 292
AjnI CCWGG 2 cut(s) 333, 430
AluBI AGCT 2 cut(s) 196, 637
AluI AGCT 2 cut(s) 196, 637
Alw21I GWGCWC 1 cut(s) 198
AlwI GGATC 5 cut(s) 291, 304, 310, 481, 592
Ama87I CYCGRG 1 cut(s) 320
AoxI GGCC 6 cut(s) 166, 174, 178, 265, 447, 631
AspLEI GCGC 1 cut(s) 389
AspS9I GGNCC 4 cut(s) 81, 428, 458, 600
AsuC2I CCSGG 3 cut(s) 321, 322, 462
AsuHPI GGTGA 4 cut(s) 340, 353, 553, 574
AvaI CYCGRG 1 cut(s) 320
AvaII GGWCC 4 cut(s) 81, 428, 458, 600
BaeGI GKGCMC 1 cut(s) 263
BalI TGGCCA 2 cut(s) 449, 633
BamHI GGATCC 1 cut(s) 296
BanI GGYRCC 2 cut(s) 362, 386
BanII GRGCYC 2 cut(s) 198, 241
BbrPI CACGTG 1 cut(s) 526
BbsI GAAGAC 1 cut(s) 67
Bbv12I GWGCWC 1 cut(s) 198
BccI CCATC 2 cut(s) 133, 184
BceAI ACGGC 3 cut(s) 376, 400, 532
BciT130I CCWGG 2 cut(s) 335, 432
BcnI CCSGG 3 cut(s) 321, 322, 462
BfaI CTAG 2 cut(s) 35, 643
BfoI RGCGCY 1 cut(s) 390
BfuAI ACCTGC 2 cut(s) 529, 601
BglI GCCNNNNNGGC 1 cut(s) 273
BisI GCNGC 1 cut(s) 268
BlsI GCNGC 1 cut(s) 269
Bme1390I CCNGG 5 cut(s) 321, 322, 335, 432, 462
Bme18I GGWCC 4 cut(s) 81, 428, 458, 600
BmeT110I CYCGRG 1 cut(s) 320
BmgT120I GGNCC 4 cut(s) 81, 428, 458, 600
BmiI GGNNCC 6 cut(s) 298, 364, 388, 459, 460, 466
BmrFI CCNGG 5 cut(s) 321, 322, 335, 432, 462
BpiI GAAGAC 1 cut(s) 67
BpuMI CCSGG 3 cut(s) 321, 322, 462
BsaAI YACGTR 1 cut(s) 526
BsaHI GRCGYC 1 cut(s) 387
BsaJI CCNNGG 5 cut(s) 222, 319, 320, 334, 444
BsaWI WCCGGW 2 cut(s) 365, 425
Bsc4I CCNNNNNNNGG 2 cut(s) 223, 292
Bse118I RCCGGY 3 cut(s) 172, 176, 248
Bse3DI GCAATG 1 cut(s) 132
BseBI CCWGG 2 cut(s) 335, 432
BseDI CCNNGG 5 cut(s) 222, 319, 320, 334, 444
BseGI GGATG 1 cut(s) 562
BseLI CCNNNNNNNGG 2 cut(s) 223, 292
BseMI GCAATG 1 cut(s) 132
BseMII CTCAG 1 cut(s) 491
BseRI GAGGAG 1 cut(s) 384
BseSI GKGCMC 1 cut(s) 263
BseX3I CGGCCG 2 cut(s) 174, 178
BseYI CCCAGC 1 cut(s) 18
BsgI GTGCAG 2 cut(s) 229, 475
Bsh1236I CGCG 5 cut(s) 72, 224, 312, 398, 455
Bsh1285I CGRYCG 3 cut(s) 162, 177, 181
BshFI GGCC 6 cut(s) 168, 176, 180, 267, 449, 633
BshNI GGYRCC 2 cut(s) 362, 386
BsiEI CGRYCG 3 cut(s) 162, 177, 181
BsiHKAI GWGCWC 1 cut(s) 198
BsiHKCI CYCGRG 1 cut(s) 320
BsiSI CCGG 9 cut(s) 173, 177, 249, 273, 321, 354, 366, 426, 462
BslFI GGGAC 1 cut(s) 444
BslI CCNNNNNNNGG 2 cut(s) 223, 292
BsmFI GGGAC 1 cut(s) 444
BsnI GGCC 6 cut(s) 168, 176, 180, 267, 449, 633
BsoBI CYCGRG 1 cut(s) 320
Bsp1286I GDGCHC 3 cut(s) 198, 241, 263
Bsp143I GATC 7 cut(s) 159, 296, 315, 378, 473, 543, 584
Bsp19I CCATGG 1 cut(s) 444
BspANI GGCC 6 cut(s) 168, 176, 180, 267, 449, 633
BspCNI CTCAG 1 cut(s) 490
BspFNI CGCG 5 cut(s) 72, 224, 312, 398, 455
BspLI GGNNCC 6 cut(s) 298, 364, 388, 459, 460, 466
BspMI ACCTGC 2 cut(s) 529, 601
BspPI GGATC 5 cut(s) 291, 304, 310, 481, 592
BspQI GCTCTTC 1 cut(s) 203
BspT107I GGYRCC 2 cut(s) 362, 386
BsrBI CCGCTC 1 cut(s) 270
BsrDI GCAATG 1 cut(s) 132
BsrFI RCCGGY 3 cut(s) 172, 176, 248
BssAI RCCGGY 3 cut(s) 172, 176, 248
BssECI CCNNGG 5 cut(s) 222, 319, 320, 334, 444
BssMI GATC 7 cut(s) 159, 296, 315, 378, 473, 543, 584
BssNI GRCGYC 1 cut(s) 387
BssT1I CCWWGG 1 cut(s) 444
Bst2UI CCWGG 2 cut(s) 335, 432
Bst4CI ACNGT 1 cut(s) 629
Bst6I CTCTTC 1 cut(s) 203
BstACI GRCGYC 1 cut(s) 387
BstBAI YACGTR 1 cut(s) 526
BstC8I GCNNGC 6 cut(s) 170, 174, 178, 278, 521, 635
BstDEI CTNAG 1 cut(s) 477
BstDSI CCRYGG 2 cut(s) 222, 444
BstF5I GGATG 1 cut(s) 562
BstFNI CGCG 5 cut(s) 72, 224, 312, 398, 455
BstH2I RGCGCY 1 cut(s) 390
BstHHI GCGC 1 cut(s) 389
BstKTI GATC 7 cut(s) 162, 299, 318, 381, 476, 546, 587
BstMBI GATC 7 cut(s) 159, 296, 315, 378, 473, 543, 584
BstMCI CGRYCG 3 cut(s) 162, 177, 181
BstMWI GCNNNNNNNGC 4 cut(s) 258, 267, 273, 395
BstNI CCWGG 2 cut(s) 335, 432
BstSCI CCNGG 5 cut(s) 319, 320, 333, 430, 460
BstSLI GKGCMC 1 cut(s) 263
BstUI CGCG 5 cut(s) 72, 224, 312, 398, 455
BstV2I GAAGAC 1 cut(s) 67
BstX2I RGATCY 3 cut(s) 296, 473, 584
BstYI RGATCY 3 cut(s) 296, 473, 584
BstZI CGGCCG 2 cut(s) 174, 178
BsuRI GGCC 6 cut(s) 168, 176, 180, 267, 449, 633
BtgI CCRYGG 2 cut(s) 222, 444
BtsCI GGATG 1 cut(s) 562
BveI ACCTGC 2 cut(s) 529, 601
Cac8I GCNNGC 6 cut(s) 170, 174, 178, 278, 521, 635
CfoI GCGC 1 cut(s) 389
Cfr10I RCCGGY 3 cut(s) 172, 176, 248
Cfr13I GGNCC 4 cut(s) 81, 428, 458, 600
Cfr42I CCGCGG 1 cut(s) 225
Cfr9I CCCGGG 1 cut(s) 320
CseI GACGC 1 cut(s) 61
CviAII CATG 3 cut(s) 154, 328, 445
DdeI CTNAG 1 cut(s) 477
DinI GGCGCC 1 cut(s) 388
DpnI GATC 7 cut(s) 161, 298, 317, 380, 475, 545, 586
DpnII GATC 7 cut(s) 159, 296, 315, 378, 473, 543, 584
DraIII CACNNNGTG 1 cut(s) 313
EaeI YGGCCR 4 cut(s) 174, 178, 447, 631
EagI CGGCCG 2 cut(s) 174, 178
Eam1104I CTCTTC 1 cut(s) 203
EarI CTCTTC 1 cut(s) 203
EciI GGCGGA 1 cut(s) 289
Ecl136II GAGCTC 1 cut(s) 196
EclXI CGGCCG 2 cut(s) 174, 178
Eco130I CCWWGG 1 cut(s) 444
Eco24I GRGCYC 2 cut(s) 198, 241
Eco47I GGWCC 4 cut(s) 81, 428, 458, 600
Eco52I CGGCCG 2 cut(s) 174, 178
Eco53kI GAGCTC 1 cut(s) 196
Eco57I CTGAAG 2 cut(s) 61, 217
Eco72I CACGTG 1 cut(s) 526
Eco88I CYCGRG 1 cut(s) 320
EcoICRI GAGCTC 1 cut(s) 196
EcoO109I RGGNCCY 3 cut(s) 81, 458, 600
EcoRII CCWGG 2 cut(s) 333, 430
EcoT14I CCWWGG 1 cut(s) 444
EcoT38I GRGCYC 2 cut(s) 198, 241
EgeI GGCGCC 1 cut(s) 388
EheI GGCGCC 1 cut(s) 388
ErhI CCWWGG 1 cut(s) 444
FaeI CATG 3 cut(s) 157, 331, 448
FaiI YATR 7 cut(s) 13, 15, 24, 62, 155, 329, 446
FaqI GGGAC 1 cut(s) 444
FatI CATG 3 cut(s) 153, 327, 444
FauI CCCGC 4 cut(s) 53, 77, 224, 448
Fnu4HI GCNGC 1 cut(s) 268
FokI GGATG 1 cut(s) 569
FriOI GRGCYC 2 cut(s) 198, 241
FseI GGCCGGCC 1 cut(s) 180
Fsp4HI GCNGC 1 cut(s) 268
FspBI CTAG 2 cut(s) 35, 643
GlaI GCGC 1 cut(s) 388
GluI GCNGC 1 cut(s) 268
GsaI CCCAGC 1 cut(s) 22
HaeII RGCGCY 1 cut(s) 390
HaeIII GGCC 6 cut(s) 168, 176, 180, 267, 449, 633
HapII CCGG 9 cut(s) 173, 177, 249, 273, 321, 354, 366, 426, 462
HgaI GACGC 1 cut(s) 61
HhaI GCGC 1 cut(s) 389
Hin1I GRCGYC 1 cut(s) 387
Hin1II CATG 3 cut(s) 157, 331, 448
Hin6I GCGC 1 cut(s) 387
HinP1I GCGC 1 cut(s) 387
HinfI GANTC 2 cut(s) 183, 374
HpaII CCGG 9 cut(s) 173, 177, 249, 273, 321, 354, 366, 426, 462
HphI GGTGA 4 cut(s) 340, 353, 553, 574
Hpy166II GTNNAC 1 cut(s) 133
Hpy188I TCNGA 2 cut(s) 164, 584
Hpy188III TCNNGA 5 cut(s) 79, 187, 412, 574, 588
Hpy8I GTNNAC 1 cut(s) 133
Hpy99I CGWCG 1 cut(s) 518
HpyAV CCTTC 4 cut(s) 250, 313, 571, 591
HpyCH4III ACNGT 1 cut(s) 629
HpyCH4IV ACGT 1 cut(s) 525
HpyCH4V TGCA 2 cut(s) 246, 492
HpyF10VI GCNNNNNNNGC 4 cut(s) 258, 267, 273, 395
HpyF3I CTNAG 1 cut(s) 477
HpySE526I ACGT 1 cut(s) 525
Hsp92I GRCGYC 1 cut(s) 387
Hsp92II CATG 3 cut(s) 157, 331, 448
HspAI GCGC 1 cut(s) 387
KasI GGCGCC 1 cut(s) 386
KflI GGGWCCC 1 cut(s) 458
KroI GCCGGC 2 cut(s) 172, 176
KroNI GCCGGC 2 cut(s) 174, 178
KspI CCGCGG 1 cut(s) 225
Kzo9I GATC 7 cut(s) 159, 296, 315, 378, 473, 543, 584
LguI GCTCTTC 1 cut(s) 203
LmnI GCTCC 2 cut(s) 193, 275
MaeI CTAG 2 cut(s) 35, 643
MaeII ACGT 1 cut(s) 525
MaeIII GTNAC 1 cut(s) 341
MalI GATC 7 cut(s) 161, 298, 317, 380, 475, 545, 586
MbiI CCGCTC 1 cut(s) 270
MboI GATC 7 cut(s) 159, 296, 315, 378, 473, 543, 584
MboII GAAGA 5 cut(s) 67, 190, 427, 475, 577
MflI RGATCY 3 cut(s) 296, 473, 584
MhlI GDGCHC 3 cut(s) 198, 241, 263
MlsI TGGCCA 2 cut(s) 449, 633
MluNI TGGCCA 2 cut(s) 449, 633
Mly113I GGCGCC 1 cut(s) 387
MlyI GAGTC 1 cut(s) 383
MmeI TCCRAC 1 cut(s) 562
MnlI CCTC 6 cut(s) 158, 293, 332, 362, 541, 613
Mox20I TGGCCA 2 cut(s) 449, 633
MroNI GCCGGC 2 cut(s) 172, 176
MscI TGGCCA 2 cut(s) 449, 633
Msp20I TGGCCA 2 cut(s) 449, 633
MspA1I CMGCKG 1 cut(s) 224
MspI CCGG 9 cut(s) 173, 177, 249, 273, 321, 354, 366, 426, 462
MspR9I CCNGG 5 cut(s) 321, 322, 335, 432, 462
MvaI CCWGG 2 cut(s) 335, 432
MvnI CGCG 5 cut(s) 72, 224, 312, 398, 455
MwoI GCNNNNNNNGC 4 cut(s) 258, 267, 273, 395
NaeI GCCGGC 2 cut(s) 174, 178
NarI GGCGCC 1 cut(s) 387
NciI CCSGG 3 cut(s) 321, 322, 462
NcoI CCATGG 1 cut(s) 444
NdeII GATC 7 cut(s) 159, 296, 315, 378, 473, 543, 584
NgoMIV GCCGGC 2 cut(s) 172, 176
NlaIII CATG 3 cut(s) 157, 331, 448
NlaIV GGNNCC 6 cut(s) 298, 364, 388, 459, 460, 466
NmuCI GTSAC 1 cut(s) 341
PaqCI CACCTGC 2 cut(s) 529, 601
PciSI GCTCTTC 1 cut(s) 203
PcsI WCGNNNNNNNCGW 1 cut(s) 522
PdiI GCCGGC 2 cut(s) 174, 178
PfeI GAWTC 1 cut(s) 183
PfoI TCCNGGA 1 cut(s) 460
PkrI GCNGC 1 cut(s) 269
Ple19I CGATCG 1 cut(s) 162
PleI GAGTC 1 cut(s) 382
PluTI GGCGCC 1 cut(s) 390
PmaCI CACGTG 1 cut(s) 526
PmlI CACGTG 1 cut(s) 526
PpsI GAGTC 1 cut(s) 382
Ppu21I YACGTR 1 cut(s) 526
PpuMI RGGWCCY 3 cut(s) 81, 458, 600
PsiI TTATAA 1 cut(s) 62
Psp124BI GAGCTC 1 cut(s) 198
Psp5II RGGWCCY 3 cut(s) 81, 458, 600
Psp6I CCWGG 2 cut(s) 333, 430
PspCI CACGTG 1 cut(s) 526
PspFI CCCAGC 1 cut(s) 18
PspGI CCWGG 2 cut(s) 333, 430
PspN4I GGNNCC 6 cut(s) 298, 364, 388, 459, 460, 466
PspPI GGNCC 4 cut(s) 81, 428, 458, 600
PspPPI RGGWCCY 3 cut(s) 81, 458, 600
PsuI RGATCY 3 cut(s) 296, 473, 584
PvuI CGATCG 1 cut(s) 162
RigI GGCCGGCC 1 cut(s) 180
SacI GAGCTC 1 cut(s) 198
SacII CCGCGG 1 cut(s) 225
SapI GCTCTTC 1 cut(s) 203
SatI GCNGC 1 cut(s) 268
Sau3AI GATC 7 cut(s) 159, 296, 315, 378, 473, 543, 584
Sau96I GGNCC 4 cut(s) 81, 428, 458, 600
SchI GAGTC 1 cut(s) 383
ScrFI CCNGG 5 cut(s) 321, 322, 335, 432, 462
SduI GDGCHC 3 cut(s) 198, 241, 263
SfoI GGCGCC 1 cut(s) 388
Sfr303I CCGCGG 1 cut(s) 225
SgrAI CRCCGGYG 1 cut(s) 248
SgrBI CCGCGG 1 cut(s) 225
SinI GGWCC 4 cut(s) 81, 428, 458, 600
SmaI CCCGGG 1 cut(s) 322
SspDI GGCGCC 1 cut(s) 386
SspI AATATT 1 cut(s) 438
SspMI CTAG 2 cut(s) 35, 643
SstI GAGCTC 1 cut(s) 198
StyD4I CCNGG 5 cut(s) 319, 320, 333, 430, 460
StyI CCWWGG 1 cut(s) 444
TaaI ACNGT 1 cut(s) 629
TaiI ACGT 1 cut(s) 528
TaqI TCGA 5 cut(s) 377, 513, 546, 573, 605
TaqII GACCGA 1 cut(s) 518
TauI GCSGC 1 cut(s) 270
TfiI GAWTC 1 cut(s) 183
TseFI GTSAC 1 cut(s) 341
Tsp45I GTSAC 1 cut(s) 341
TspDTI ATGAA 2 cut(s) 316, 475
TspGWI ACGGA 1 cut(s) 486
TspMI CCCGGG 1 cut(s) 320
VpaK11BI GGWCC 4 cut(s) 81, 428, 458, 600
XmaI CCCGGG 1 cut(s) 320
XspI CTAG 2 cut(s) 35, 643
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.