pycom10g26990

May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
pyrus_communis
Chr10
OG0011158
Physical Location & Seq
Reverse (-)
28111679 .. 28113414
1736 bp
Loading structure...
UTR
Exon/CDS
Intron
N/A

Sequence Viewer

Length: 732 bp
ATGGCTCAGGCAGTCGAAGAATGGTACAAGCAGATGCCCGTCATCACCCGCTCGTACCTCACCGCAGCTGTTCTCACCAACATCGGTTGCTCCCTCGACATAATTTCTCCTCACAATCTGTACTTGAACCCTAATCTAGTGGTCAAGCAGTATCAATTCTGGCGGCTCGTTACTAATTTCCTTTACTTCCGGAAAATGGACTTGGATTTCATGTTCCACATGTTCTTTCTTGCTCGGTACTGCAAGCTTCTTGAAGAGAACTCTTTTCGAGGACGGACTGCGGATTTCTTTTATATGCTCTTATTTGGTGCCACTATGTTGACTGGGATAGTTCTGGTTGGAGGGATGATACCTCATTTGTCTGAGTCGTTTGCAAAGATTATATTCCTCAGCAACTCACTAACGTTCATGATGGTCTATGTGTGGAGCAAGCAAAATCCTTTCATTCATATGAGCTTCTTGGGCCTCTTTACCTTCACAGCAGCTTACCTACCTTGGGTTCTTCTGACGTTCTCCGTCTTGGTCGGAGCTAGCCCTTGGGTGGATCTTTTGGGAATGATTGCCGGTCATGCCTATTACTTTCTAGAAGATGTTTACCCACGAATGACAGGTCGCCGGCCCTTGAGAACCCCTTCACTTATCAAAGCACTATTTGCCGATGACCCTGTTGTGGTGGCACGACCAAATGTGAGATTTGCACCACCACCCGTGGAGGAACTTCACCAAGATTAA
Functional Annotation
Gene Ontology
Molecular Function
Biological Process
Cellular Component
No ontology terms assigned.
KEGG Pathways
Metabolic & Signaling
ko04141 map04141
Pfam Domains
Protein Families
DER1

Protein Analysis

244

Amino Acids

28.1

Weight (kDa)

8.49

Isoelectric Point (pI)

39.86

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
DER1 PF04511 12 - 212 2.8e-62 Der1-like family
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
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Publication-ready
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Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AccB1I GGYRCC 1 cut(s) 308
AccBSI CCGCTC 1 cut(s) 51
AccIII TCCGGA 1 cut(s) 189
AciI CCGC 4 cut(s) 49, 63, 163, 281
AclI AACGTT 1 cut(s) 404
AclWI GGATC 1 cut(s) 552
AfaI GTAC 4 cut(s) 26, 56, 122, 239
AfiI CCNNNNNNNGG 4 cut(s) 196, 496, 541, 670
AflIII ACRYGT 1 cut(s) 219
AgsI TTSAA 2 cut(s) 127, 254
AjuI GAANNNNNNNTTGG 2 cut(s) 185, 217
AloI GAACNNNNNNTCC 2 cut(s) 197, 229
AluBI AGCT 5 cut(s) 68, 247, 456, 485, 530
AluI AGCT 5 cut(s) 68, 247, 456, 485, 530
AlwI GGATC 1 cut(s) 552
Aor13HI TCCGGA 1 cut(s) 189
AoxI GGCC 2 cut(s) 463, 617
ApeKI GCWGC 2 cut(s) 65, 482
ArsI GACNNNNNNTTYG 2 cut(s) 595, 627
Asp700I GAANNNNTTC 1 cut(s) 631
AspS9I GGNCC 2 cut(s) 463, 618
AsuHPI GGTGA 4 cut(s) 37, 52, 67, 713
AsuNHI GCTAGC 1 cut(s) 530
BanI GGYRCC 1 cut(s) 308
BbvCI CCTCAGC 1 cut(s) 389
BbvI GCAGC 2 cut(s) 77, 494
BccI CCATC 1 cut(s) 406
BfaI CTAG 3 cut(s) 137, 531, 584
BisI GCNGC 3 cut(s) 66, 164, 483
BlsI GCNGC 3 cut(s) 67, 165, 484
BmgT120I GGNCC 2 cut(s) 463, 618
BmiI GGNNCC 1 cut(s) 310
BmrI ACTGGG 1 cut(s) 333
BmsI GCATC 1 cut(s) 24
BmtI GCTAGC 1 cut(s) 534
BmuI ACTGGG 1 cut(s) 333
Bpu10I CCTNAGC 2 cut(s) 6, 389
BpuEI CTTGAG 1 cut(s) 643
BsaJI CCNNGG 3 cut(s) 494, 536, 708
BsaWI WCCGGW 1 cut(s) 189
Bsc4I CCNNNNNNNGG 4 cut(s) 196, 496, 541, 670
Bse118I RCCGGY 2 cut(s) 563, 615
Bse1I ACTGG 1 cut(s) 328
BseAI TCCGGA 1 cut(s) 189
BseDI CCNNGG 3 cut(s) 494, 536, 708
BseGI GGATG 1 cut(s) 351
BseLI CCNNNNNNNGG 4 cut(s) 196, 496, 541, 670
BseMII CTCAG 3 cut(s) 20, 354, 403
BseNI ACTGG 1 cut(s) 328
BseRI GAGGAG 1 cut(s) 99
BseXI GCAGC 2 cut(s) 77, 494
BshFI GGCC 2 cut(s) 465, 619
BshNI GGYRCC 1 cut(s) 308
BsiSI CCGG 3 cut(s) 190, 564, 616
BslI CCNNNNNNNGG 4 cut(s) 196, 496, 541, 670
BsnI GGCC 2 cut(s) 465, 619
Bsp13I TCCGGA 1 cut(s) 189
Bsp143I GATC 1 cut(s) 544
BspACI CCGC 4 cut(s) 49, 63, 163, 281
BspANI GGCC 2 cut(s) 465, 619
BspCNI CTCAG 3 cut(s) 19, 355, 402
BspEI TCCGGA 1 cut(s) 189
BspHI TCATGA 1 cut(s) 408
BspLI GGNNCC 1 cut(s) 310
BspOI GCTAGC 1 cut(s) 534
BspPI GGATC 1 cut(s) 552
BspT107I GGYRCC 1 cut(s) 308
BsrBI CCGCTC 1 cut(s) 51
BsrFI RCCGGY 2 cut(s) 563, 615
BsrI ACTGG 1 cut(s) 328
BssAI RCCGGY 2 cut(s) 563, 615
BssECI CCNNGG 3 cut(s) 494, 536, 708
BssMI GATC 1 cut(s) 544
BssT1I CCWWGG 2 cut(s) 494, 536
Bst6I CTCTTC 1 cut(s) 249
BstAPI GCANNNNNTGC 1 cut(s) 653
BstC8I GCNNGC 4 cut(s) 245, 431, 532, 617
BstDEI CTNAG 3 cut(s) 6, 363, 389
BstDSI CCRYGG 1 cut(s) 708
BstF5I GGATG 1 cut(s) 351
BstKTI GATC 1 cut(s) 547
BstMBI GATC 1 cut(s) 544
BstMWI GCNNNNNNNGC 3 cut(s) 462, 569, 653
BstNSI RCATGY 1 cut(s) 223
BstV1I GCAGC 2 cut(s) 77, 494
BstX2I RGATCY 1 cut(s) 544
BstYI RGATCY 1 cut(s) 544
BsuRI GGCC 2 cut(s) 465, 619
BtgI CCRYGG 1 cut(s) 708
BtsCI GGATG 1 cut(s) 351
Cac8I GCNNGC 4 cut(s) 245, 431, 532, 617
CciI TCATGA 1 cut(s) 408
Cfr10I RCCGGY 2 cut(s) 563, 615
Cfr13I GGNCC 2 cut(s) 463, 618
Csp6I GTAC 4 cut(s) 25, 55, 121, 238
CviAII CATG 4 cut(s) 211, 220, 409, 569
CviQI GTAC 4 cut(s) 25, 55, 121, 238
DdeI CTNAG 3 cut(s) 6, 363, 389
DpnI GATC 1 cut(s) 546
DpnII GATC 1 cut(s) 544
Eam1104I CTCTTC 1 cut(s) 249
EarI CTCTTC 1 cut(s) 249
Eco130I CCWWGG 2 cut(s) 494, 536
EcoT14I CCWWGG 2 cut(s) 494, 536
ErhI CCWWGG 2 cut(s) 494, 536
FaeI CATG 4 cut(s) 214, 223, 412, 572
FatI CATG 4 cut(s) 210, 219, 408, 568
FauI CCCGC 1 cut(s) 56
FauNDI CATATG 1 cut(s) 450
Fnu4HI GCNGC 3 cut(s) 66, 164, 483
FokI GGATG 1 cut(s) 358
Fsp4HI GCNGC 3 cut(s) 66, 164, 483
FspBI CTAG 3 cut(s) 137, 531, 584
GluI GCNGC 3 cut(s) 66, 164, 483
HaeIII GGCC 2 cut(s) 465, 619
HapII CCGG 3 cut(s) 190, 564, 616
Hin1II CATG 4 cut(s) 214, 223, 412, 572
HincII GTYRAC 1 cut(s) 321
HindII GTYRAC 1 cut(s) 321
HindIII AAGCTT 1 cut(s) 245
HinfI GANTC 1 cut(s) 365
HpaII CCGG 3 cut(s) 190, 564, 616
HphI GGTGA 4 cut(s) 37, 52, 67, 713
Hpy166II GTNNAC 2 cut(s) 321, 595
Hpy188I TCNGA 3 cut(s) 364, 507, 527
Hpy188III TCNNGA 4 cut(s) 190, 251, 409, 584
Hpy8I GTNNAC 2 cut(s) 321, 595
HpyAV CCTTC 2 cut(s) 484, 642
HpyCH4IV ACGT 2 cut(s) 404, 509
HpyCH4V TGCA 3 cut(s) 243, 374, 698
HpyF10VI GCNNNNNNNGC 3 cut(s) 462, 569, 653
HpyF3I CTNAG 3 cut(s) 6, 363, 389
HpySE526I ACGT 2 cut(s) 404, 509
Hsp92II CATG 4 cut(s) 214, 223, 412, 572
Kpn2I TCCGGA 1 cut(s) 189
KroI GCCGGC 1 cut(s) 615
KroNI GCCGGC 1 cut(s) 617
Kzo9I GATC 1 cut(s) 544
LmnI GCTCC 3 cut(s) 95, 426, 527
LpnPI CCDG 8 cut(s) 145, 203, 309, 320, 577, 594, 629, 678
Lsp1109I GCAGC 2 cut(s) 77, 494
LweI GCATC 1 cut(s) 24
MaeI CTAG 3 cut(s) 137, 531, 584
MaeII ACGT 2 cut(s) 404, 509
MaeIII GTNAC 1 cut(s) 169
MalI GATC 1 cut(s) 546
MbiI CCGCTC 1 cut(s) 51
MboI GATC 1 cut(s) 544
MboII GAAGA 4 cut(s) 29, 266, 494, 599
MflI RGATCY 1 cut(s) 544
MluCI AATT 3 cut(s) 102, 155, 175
MlyI GAGTC 1 cut(s) 374
MmeI TCCRAC 2 cut(s) 319, 505
MnlI CCTC 9 cut(s) 68, 104, 120, 263, 335, 363, 398, 476, 706
MroI TCCGGA 1 cut(s) 189
MroNI GCCGGC 1 cut(s) 615
MroXI GAANNNNTTC 1 cut(s) 631
MseI TTAA 1 cut(s) 730
MslI CAYNNNNRTG 1 cut(s) 449
MspA1I CMGCKG 1 cut(s) 68
MspI CCGG 3 cut(s) 190, 564, 616
MwoI GCNNNNNNNGC 3 cut(s) 462, 569, 653
NaeI GCCGGC 1 cut(s) 617
NdeI CATATG 1 cut(s) 450
NdeII GATC 1 cut(s) 544
NgoMIV GCCGGC 1 cut(s) 615
NheI GCTAGC 1 cut(s) 530
NlaIII CATG 4 cut(s) 214, 223, 412, 572
NlaIV GGNNCC 1 cut(s) 310
NspI RCATGY 1 cut(s) 223
PagI TCATGA 1 cut(s) 408
PciI ACATGT 1 cut(s) 219
PdiI GCCGGC 1 cut(s) 617
PdmI GAANNNNTTC 1 cut(s) 631
PkrI GCNGC 3 cut(s) 67, 165, 484
PleI GAGTC 1 cut(s) 373
PpsI GAGTC 1 cut(s) 373
PscI ACATGT 1 cut(s) 219
Psp1406I AACGTT 1 cut(s) 404
PspN4I GGNNCC 1 cut(s) 310
PspPI GGNCC 2 cut(s) 463, 618
PsuI RGATCY 1 cut(s) 544
PvuII CAGCTG 1 cut(s) 68
RsaI GTAC 4 cut(s) 26, 56, 122, 239
RsaNI GTAC 4 cut(s) 25, 55, 121, 238
RseI CAYNNNNRTG 1 cut(s) 449
SaqAI TTAA 1 cut(s) 730
SatI GCNGC 3 cut(s) 66, 164, 483
Sau3AI GATC 1 cut(s) 544
Sau96I GGNCC 2 cut(s) 463, 618
SchI GAGTC 1 cut(s) 374
SfaNI GCATC 1 cut(s) 24
SmiMI CAYNNNNRTG 1 cut(s) 449
SmlI CTYRAG 1 cut(s) 622
SmoI CTYRAG 1 cut(s) 622
Sse9I AATT 3 cut(s) 102, 155, 175
SsiI CCGC 4 cut(s) 49, 63, 163, 281
SspMI CTAG 3 cut(s) 137, 531, 584
StyI CCWWGG 2 cut(s) 494, 536
TaiI ACGT 2 cut(s) 407, 512
TaqI TCGA 3 cut(s) 15, 96, 268
TasI AATT 3 cut(s) 102, 155, 175
TatI WGTACW 1 cut(s) 120
TauI GCSGC 1 cut(s) 166
Tru1I TTAA 1 cut(s) 730
Tru9I TTAA 1 cut(s) 730
TseI GCWGC 2 cut(s) 65, 482
TspDTI ATGAA 4 cut(s) 199, 397, 433, 437
TspGWI ACGGA 2 cut(s) 289, 505
XbaI TCTAGA 1 cut(s) 583
XceI RCATGY 1 cut(s) 223
XmnI GAANNNNTTC 1 cut(s) 631
XspI CTAG 3 cut(s) 137, 531, 584
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.