pycom12397g00240

Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
pyrus_communis
tig00012397
OG0016119
Physical Location & Seq
Reverse (-)
123071 .. 124856
1786 bp
Loading structure...
UTR
Exon/CDS
Intron
N/A

Sequence Viewer

Length: 1551 bp
ATGATCGAGCCAAGTATCACAACTTCTTCTACCCATCCTGTATATTGTCCTTTTCATTCTGTGTTGAAATATAAACTTATTATATTAGTAGGCGAGATTTTACGAAAAAGGTTCTTTATATTCCTTTATATTCATAGCATAGGAGAAACTACTATTTTTTTTTTTTTTTTTTTCAATATCCCCTCGTTATTAGGGCAAGAAAGTTCTATGGAAAAATGGCGGTTCGATTCGATGTTGTTTAACGGGGAGTTAGAATACAGGTGTAGGTTAAGTAAATCAATGGACAGTCTTGGTCCTTTTGAAAATACCAGTTCGGCGACAGATACATTCGGAATTTCATATCTGATGACACTTTTTTCGTTAGGGATAGTAATAGGGACAGTTATTCCATATATTTTGATATTGAAAATAAAAATTTTGAGATTGACAACAACCACTTCTAGTTATATAAATAATGCACCCCAAAGTGACGATACTCGCCACGATCGTTACATGTATGATACTAATTCTCATCATAGTTGGAATAATCACATTAATAGTTCTATTGACAGTTATCTTGGTTCTCAAATTTGTATTGATAGTTATATTTTAAGCAACAGTAACAATTACAGTGACAGCTACATTTATAGTTACATTTGTGGCGAAAGCGTAAATAGTAGTAAAAGCGAGAGTTCCAGTATAAAAACTAGCACAGATGATAGTGATTTTAGTATAAGTTCTAATAATTTAAATGTAACTCAAAAATACAGGCATTTGTGGATTCAATGCGAAAATTGTTATGGATTAAATTATAAGAAATTTTTAAAATCAAAAATGAATATTTGTGAACAATGTGGATGTCATTTGAAAATGAGTAGTTTTGATAGAATCGAACTTTCGATTGATCCCGGTACTTGGGATCCTATGAACGAAGACATGGTCTCTCTGGATCCCATTGAATTTCATTCGGAGGAGGAACCTTATAAAGATCGTATTGATTCTTATCAAAAAAATACAGGATTAACTGAGGCTGTTCAAACAGGCACAGGTCAACTAAATGGTATTCCCGTAGCAATTGGTGTTATGGATTTTCAGTTTATGGGTGGTAGTATGGGATCTGTAGTGGGCGAAAAAATCACACGTTTGGCCGAGTATGCTACCAATCAATTTTTACCTCTTATTCTAGTGTGTGCTTCCGGAGGAGCACGCATGCAAGAAGGAAGCTTGAGCTTGATGCAAATGGCTAAAATATCTTCCGCTTTATATGATTATCAATTAAATAAAAAGTTATTTTATGTAGCAATCCTTACATCCCCTACCACAGGCGGGGTGACGGCTAGTTTTGGTATGTTGGGAGATATCATTATTGCCGAACCCAATGCTTATATTGCATTTGCAGGTAAAAGAGTAATTGAACAAACATTGAATAAGACAGTACCTGAGGATTCACAAGTGGCTGAATATTTATTCCATAAGGGCTTATTCGATCGAATCGTACCACGTAATCGTTTAAAGGGCGTTCTGAGTGAGTTATTTCGGCTACATGCTTTCTTTCCTTTGAATGAAAATTAG
Functional Annotation
Gene Ontology
Molecular Function
Biological Process
Cellular Component
No ontology terms assigned.
KEGG Pathways
Metabolic & Signaling
ko00061 ko00195 ko00620 ko00640 ko00720 ko01100 ko01110 ko01120 ko01130 ko01200 ko01212 map00061 map00195 map00620 map00640 map00720 map01100 map01110 map01120 map01130 map01200 map01212
Pfam Domains
Protein Families
Carboxyl_trans PSI_8

Protein Analysis

517

Amino Acids

58.31

Weight (kDa)

5.69

Isoelectric Point (pI)

41.81

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
Carboxyl_trans PF01039 309 - 477 3.4e-21 Carboxyl transferase domain
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
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Publication-ready
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Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AanI TTATAA 2 cut(s) 792, 963
Acc36I ACCTGC 1 cut(s) 1367
AccIII TCCGGA 1 cut(s) 1175
AciI CCGC 3 cut(s) 220, 1236, 1305
AclWI GGATC 6 cut(s) 878, 893, 906, 923, 936, 1102
AcoI YGGCCR 1 cut(s) 1125
AcsI RAATTY 5 cut(s) 333, 414, 567, 797, 938
AfaI GTAC 3 cut(s) 892, 1416, 1476
AfiI CCNNNNNNNGG 3 cut(s) 894, 1301, 1305
AflIII ACRYGT 2 cut(s) 492, 1118
AluBI AGCT 3 cut(s) 618, 1203, 1209
AluI AGCT 3 cut(s) 618, 1203, 1209
Alw21I GWGCWC 1 cut(s) 1186
Alw26I GTCTC 1 cut(s) 925
AlwI GGATC 6 cut(s) 878, 893, 906, 923, 936, 1102
AlwNI CAGNNNCTG 1 cut(s) 1418
Aor13HI TCCGGA 1 cut(s) 1175
AoxI GGCC 1 cut(s) 1125
ApoI RAATTY 5 cut(s) 333, 414, 567, 797, 938
ArsI GACNNNNNNTTYG 4 cut(s) 340, 372, 903, 935
AseI ATTAAT 1 cut(s) 534
AspS9I GGNCC 1 cut(s) 293
AsuC2I CCSGG 1 cut(s) 888
AsuHPI GGTGA 1 cut(s) 1321
AvaII GGWCC 1 cut(s) 293
AxyI CCTNAGG 1 cut(s) 1419
BamHI GGATCC 2 cut(s) 898, 928
BarI GAAGNNNNNNTAC 2 cut(s) 7, 39
BbsI GAAGAC 1 cut(s) 918
Bbv12I GWGCWC 1 cut(s) 1186
BccI CCATC 1 cut(s) 42
BceAI ACGGC 1 cut(s) 1329
BcgI CGANNNNNNTGC 2 cut(s) 1340, 1374
BcnI CCSGG 1 cut(s) 888
BcoDI GTCTC 1 cut(s) 925
BfaI CTAG 4 cut(s) 441, 687, 1163, 1317
BfmI CTRYAG 1 cut(s) 1098
BfuAI ACCTGC 1 cut(s) 1367
Bme1390I CCNGG 1 cut(s) 888
Bme18I GGWCC 1 cut(s) 293
BmgT120I GGNCC 1 cut(s) 293
BmiI GGNNCC 3 cut(s) 900, 930, 957
BmrFI CCNGG 1 cut(s) 888
BmsI GCATC 1 cut(s) 1203
BpiI GAAGAC 1 cut(s) 918
BpuEI CTTGAG 1 cut(s) 1225
BpuMI CCSGG 1 cut(s) 888
BsaAI YACGTR 1 cut(s) 1481
BsaBI GATNNNNATC 1 cut(s) 981
BsaI GGTCTC 1 cut(s) 925
BsaWI WCCGGW 1 cut(s) 1175
Bsc4I CCNNNNNNNGG 3 cut(s) 894, 1301, 1305
Bse1I ACTGG 2 cut(s) 309, 675
Bse21I CCTNAGG 1 cut(s) 1419
Bse8I GATNNNNATC 1 cut(s) 981
BseAI TCCGGA 1 cut(s) 1175
BseGI GGATG 3 cut(s) 34, 842, 1289
BseJI GATNNNNATC 1 cut(s) 981
BseLI CCNNNNNNNGG 3 cut(s) 894, 1301, 1305
BseMII CTCAG 3 cut(s) 996, 1410, 1493
BseNI ACTGG 2 cut(s) 309, 675
BseRI GAGGAG 2 cut(s) 965, 1194
Bsh1285I CGRYCG 2 cut(s) 487, 1468
BshFI GGCC 1 cut(s) 1127
BsiEI CGRYCG 2 cut(s) 487, 1468
BsiHKAI GWGCWC 1 cut(s) 1186
BsiSI CCGG 2 cut(s) 888, 1176
BslFI GGGAC 1 cut(s) 391
BslI CCNNNNNNNGG 3 cut(s) 894, 1301, 1305
BsmAI GTCTC 1 cut(s) 925
BsmFI GGGAC 1 cut(s) 391
BsnI GGCC 1 cut(s) 1127
Bso31I GGTCTC 1 cut(s) 925
Bsp1286I GDGCHC 1 cut(s) 1186
Bsp13I TCCGGA 1 cut(s) 1175
Bsp143I GATC 8 cut(s) 3, 484, 883, 898, 928, 967, 1094, 1465
BspACI CCGC 3 cut(s) 220, 1236, 1305
BspANI GGCC 1 cut(s) 1127
BspCNI CTCAG 3 cut(s) 997, 1411, 1494
BspEI TCCGGA 1 cut(s) 1175
BspLI GGNNCC 3 cut(s) 900, 930, 957
BspMI ACCTGC 1 cut(s) 1367
BspPI GGATC 6 cut(s) 878, 893, 906, 923, 936, 1102
BspTNI GGTCTC 1 cut(s) 925
BsrI ACTGG 2 cut(s) 309, 675
BssMI GATC 8 cut(s) 3, 484, 883, 898, 928, 967, 1094, 1465
Bst4CI ACNGT 6 cut(s) 287, 382, 551, 599, 611, 1414
BstBAI YACGTR 1 cut(s) 1481
BstC8I GCNNGC 2 cut(s) 1186, 1190
BstDEI CTNAG 3 cut(s) 1005, 1419, 1502
BstENI CCTNNNNNAGG 1 cut(s) 1299
BstF5I GGATG 3 cut(s) 34, 842, 1289
BstKTI GATC 8 cut(s) 6, 487, 886, 901, 931, 970, 1097, 1468
BstMAI GTCTC 1 cut(s) 925
BstMBI GATC 8 cut(s) 3, 484, 883, 898, 928, 967, 1094, 1465
BstMCI CGRYCG 2 cut(s) 487, 1468
BstMWI GCNNNNNNNGC 2 cut(s) 1133, 1367
BstNSI RCATGY 3 cut(s) 496, 1192, 1526
BstSCI CCNGG 1 cut(s) 886
BstSFI CTRYAG 1 cut(s) 1098
BstV2I GAAGAC 1 cut(s) 918
BstX2I RGATCY 3 cut(s) 898, 928, 1094
BstYI RGATCY 3 cut(s) 898, 928, 1094
Bsu36I CCTNAGG 1 cut(s) 1419
BsuRI GGCC 1 cut(s) 1127
BtsCI GGATG 3 cut(s) 34, 842, 1289
BtsIMutI CAGTG 1 cut(s) 616
BveI ACCTGC 1 cut(s) 1367
Cac8I GCNNGC 2 cut(s) 1186, 1190
CaiI CAGNNNCTG 1 cut(s) 1418
Cfr13I GGNCC 1 cut(s) 293
Csp6I GTAC 3 cut(s) 891, 1415, 1475
CviAII CATG 4 cut(s) 493, 916, 1189, 1523
CviQI GTAC 3 cut(s) 891, 1415, 1475
DdeI CTNAG 3 cut(s) 1005, 1419, 1502
DpnI GATC 8 cut(s) 5, 486, 885, 900, 930, 969, 1096, 1467
DpnII GATC 8 cut(s) 3, 484, 883, 898, 928, 967, 1094, 1465
DraI TTTAAA 3 cut(s) 729, 804, 1491
EaeI YGGCCR 1 cut(s) 1125
Eco31I GGTCTC 1 cut(s) 925
Eco32I GATATC 1 cut(s) 1339
Eco47I GGWCC 1 cut(s) 293
Eco81I CCTNAGG 1 cut(s) 1419
EcoNI CCTNNNNNAGG 1 cut(s) 1299
EcoRV GATATC 1 cut(s) 1339
FaeI CATG 4 cut(s) 496, 919, 1192, 1526
FaqI GGGAC 1 cut(s) 391
FatI CATG 4 cut(s) 492, 915, 1188, 1522
FauI CCCGC 1 cut(s) 1298
FokI GGATG 3 cut(s) 21, 849, 1276
FspBI CTAG 4 cut(s) 441, 687, 1163, 1317
HaeIII GGCC 1 cut(s) 1127
HapII CCGG 2 cut(s) 888, 1176
Hin1II CATG 4 cut(s) 496, 919, 1192, 1526
HincII GTYRAC 1 cut(s) 1031
HindII GTYRAC 1 cut(s) 1031
HindIII AAGCTT 1 cut(s) 1201
HinfI GANTC 6 cut(s) 227, 760, 867, 977, 1424, 1470
HpaII CCGG 2 cut(s) 888, 1176
HphI GGTGA 1 cut(s) 1321
Hpy166II GTNNAC 2 cut(s) 827, 1031
Hpy188I TCNGA 4 cut(s) 332, 345, 949, 1503
Hpy188III TCNNGA 2 cut(s) 926, 1176
Hpy8I GTNNAC 2 cut(s) 827, 1031
HpyAV CCTTC 1 cut(s) 1190
HpyCH4III ACNGT 6 cut(s) 287, 382, 551, 599, 611, 1414
HpyCH4IV ACGT 2 cut(s) 1120, 1480
HpyCH4V TGCA 5 cut(s) 458, 1192, 1216, 1370, 1376
HpyF10VI GCNNNNNNNGC 2 cut(s) 1133, 1367
HpyF3I CTNAG 3 cut(s) 1005, 1419, 1502
HpySE526I ACGT 2 cut(s) 1120, 1480
Hsp92II CATG 4 cut(s) 496, 919, 1192, 1526
Kpn2I TCCGGA 1 cut(s) 1175
Kzo9I GATC 8 cut(s) 3, 484, 883, 898, 928, 967, 1094, 1465
LmnI GCTCC 1 cut(s) 1181
LweI GCATC 1 cut(s) 1203
MaeI CTAG 4 cut(s) 441, 687, 1163, 1317
MaeII ACGT 2 cut(s) 1120, 1480
MaeIII GTNAC 7 cut(s) 467, 488, 599, 611, 629, 733, 1309
MalI GATC 8 cut(s) 5, 486, 885, 900, 930, 969, 1096, 1467
MboI GATC 8 cut(s) 3, 484, 883, 898, 928, 967, 1094, 1465
MboII GAAGA 3 cut(s) 18, 923, 1224
MfeI CAATTG 1 cut(s) 1053
MflI RGATCY 3 cut(s) 898, 928, 1094
MhlI GDGCHC 1 cut(s) 1186
MmeI TCCRAC 1 cut(s) 500
MnlI CCTC 7 cut(s) 193, 943, 946, 1000, 1164, 1172, 1414
MroI TCCGGA 1 cut(s) 1175
MspI CCGG 2 cut(s) 888, 1176
MspR9I CCNGG 1 cut(s) 888
MunI CAATTG 1 cut(s) 1053
MwoI GCNNNNNNNGC 2 cut(s) 1133, 1367
NciI CCSGG 1 cut(s) 888
NdeII GATC 8 cut(s) 3, 484, 883, 898, 928, 967, 1094, 1465
NlaIII CATG 4 cut(s) 496, 919, 1192, 1526
NlaIV GGNNCC 3 cut(s) 900, 930, 957
NmeAIII GCCGAG 1 cut(s) 1153
NmuCI GTSAC 3 cut(s) 467, 611, 1309
NspI RCATGY 3 cut(s) 496, 1192, 1526
PaeI GCATGC 1 cut(s) 1192
PciI ACATGT 1 cut(s) 492
PcsI WCGNNNNNNNCGW 2 cut(s) 484, 1470
PfeI GAWTC 6 cut(s) 227, 760, 867, 977, 1424, 1470
PflFI GACNNNGTC 1 cut(s) 917
Ple19I CGATCG 2 cut(s) 487, 1468
Ppu21I YACGTR 1 cut(s) 1481
PscI ACATGT 1 cut(s) 492
PshBI ATTAAT 1 cut(s) 534
PsiI TTATAA 2 cut(s) 792, 963
PspN4I GGNNCC 3 cut(s) 900, 930, 957
PspPI GGNCC 1 cut(s) 293
PstNI CAGNNNCTG 1 cut(s) 1418
PsuI RGATCY 3 cut(s) 898, 928, 1094
PsyI GACNNNGTC 1 cut(s) 917
PvuI CGATCG 2 cut(s) 487, 1468
RsaI GTAC 3 cut(s) 892, 1416, 1476
RsaNI GTAC 3 cut(s) 891, 1415, 1475
Sau3AI GATC 8 cut(s) 3, 484, 883, 898, 928, 967, 1094, 1465
Sau96I GGNCC 1 cut(s) 293
ScrFI CCNGG 1 cut(s) 888
SduI GDGCHC 1 cut(s) 1186
SfaNI GCATC 1 cut(s) 1203
SfcI CTRYAG 1 cut(s) 1098
SinI GGWCC 1 cut(s) 293
SmiI ATTTAAAT 1 cut(s) 729
SmlI CTYRAG 1 cut(s) 1204
SmoI CTYRAG 1 cut(s) 1204
SphI GCATGC 1 cut(s) 1192
SsiI CCGC 3 cut(s) 220, 1236, 1305
SspI AATATT 2 cut(s) 820, 1442
SspMI CTAG 4 cut(s) 441, 687, 1163, 1317
StyD4I CCNGG 1 cut(s) 886
SwaI ATTTAAAT 1 cut(s) 729
TaaI ACNGT 6 cut(s) 287, 382, 551, 599, 611, 1414
TaiI ACGT 2 cut(s) 1123, 1483
TaqI TCGA 7 cut(s) 6, 225, 230, 870, 878, 1464, 1468
TfiI GAWTC 6 cut(s) 227, 760, 867, 977, 1424, 1470
TscAI CASTG 1 cut(s) 616
TseFI GTSAC 3 cut(s) 467, 611, 1309
Tsp45I GTSAC 3 cut(s) 467, 611, 1309
TspDTI ATGAA 6 cut(s) 44, 122, 327, 830, 920, 932
TspRI CASTG 1 cut(s) 616
Tth111I GACNNNGTC 1 cut(s) 917
VpaK11BI GGWCC 1 cut(s) 293
VspI ATTAAT 1 cut(s) 534
XagI CCTNNNNNAGG 1 cut(s) 1299
XapI RAATTY 5 cut(s) 333, 414, 567, 797, 938
XceI RCATGY 3 cut(s) 496, 1192, 1526
XspI CTAG 4 cut(s) 441, 687, 1163, 1317
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.