Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin Fzo YdjA family
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| Species | Orthologous Gene IDs |
|---|---|
| arabidopsis_thaliana | AT5G42080 AT5G42080 AT5G42080 AT5G42080 |
| fragaria_vesca | FvH4_5g04750 |
| malus_domestica | MD06G1108700.v1.1 MD14G1129600.v1.1 |
| prunus_persica | Prupe.5G121300_v2.0.a1 Prupe.5G121500_v2.0.a1 |
| pyrus_communis | pycom06g10210 |
| rosa_chinensis | RchiOBHm_Chr7g0194521 RchiOBHm_Chr7g0194601 |
| rosa_laevigata | RLG00000004190 RLG00000004194 |
| rosa_multiflora | Rmu_ssc0000261.1_g000017 Rmu_ssc0000261.1_g000020 |
| rosa_roxburghii | Rroxscaffold_3G00261250 Rroxscaffold_5G00385480 |
| rosa_rugosa | Rorug07G0016100 Rorug07G0016400 |
| rosa_samantha | Rh7AG143600 Rh7AG143900 Rh7BG144200 Rh7CG147800 Rh7CG148000 Rh7DG145400 |
| rosa_wichuraiana | Rw7G012300 |
| Enzyme | Recognition Site | Cut Count | Positions (bp) |
|---|---|---|---|
| AarI | CACCTGC | 1 cut(s) | 553 |
| Acc16I | TGCGCA | 1 cut(s) | 1748 |
| Acc36I | ACCTGC | 1 cut(s) | 553 |
| AccI | GTMKAC | 1 cut(s) | 1519 |
| AccII | CGCG | 2 cut(s) | 98, 1388 |
| AccIII | TCCGGA | 1 cut(s) | 1333 |
| AciI | CCGC | 2 cut(s) | 260, 303 |
| AclWI | GGATC | 5 cut(s) | 593, 606, 1311, 1868, 1881 |
| AcoI | YGGCCR | 1 cut(s) | 124 |
| AcsI | RAATTY | 1 cut(s) | 701 |
| AcuI | CTGAAG | 1 cut(s) | 1319 |
| AcyI | GRCGYC | 1 cut(s) | 1056 |
| AfaI | GTAC | 1 cut(s) | 658 |
| AfiI | CCNNNNNNNGG | 3 cut(s) | 713, 1214, 1300 |
| AgsI | TTSAA | 7 cut(s) | 488, 671, 935, 941, 1361, 1553, 1628 |
| AjnI | CCWGG | 4 cut(s) | 430, 898, 1063, 1351 |
| AluBI | AGCT | 7 cut(s) | 41, 226, 1178, 1205, 1339, 1382, 1803 |
| AluI | AGCT | 7 cut(s) | 41, 226, 1178, 1205, 1339, 1382, 1803 |
| Alw21I | GWGCWC | 1 cut(s) | 1936 |
| Alw26I | GTCTC | 5 cut(s) | 90, 323, 917, 1232, 1322 |
| AlwI | GGATC | 5 cut(s) | 593, 606, 1311, 1868, 1881 |
| Aor13HI | TCCGGA | 1 cut(s) | 1333 |
| AoxI | GGCC | 1 cut(s) | 124 |
| ApeKI | GCWGC | 4 cut(s) | 223, 767, 1271, 1379 |
| ApoI | RAATTY | 1 cut(s) | 701 |
| ArsI | GACNNNNNNTTYG | 2 cut(s) | 1838, 1870 |
| Asp700I | GAANNNNTTC | 3 cut(s) | 173, 287, 835 |
| AspLEI | GCGC | 4 cut(s) | 77, 100, 1388, 1749 |
| AspS9I | GGNCC | 3 cut(s) | 909, 1259, 1810 |
| AsuHPI | GGTGA | 4 cut(s) | 68, 534, 1082, 1813 |
| AvaII | GGWCC | 3 cut(s) | 909, 1259, 1810 |
| BaeI | ACNNNNGTAYC | 2 cut(s) | 1210, 1243 |
| BalI | TGGCCA | 1 cut(s) | 126 |
| BamHI | GGATCC | 2 cut(s) | 598, 1873 |
| BauI | CACGAG | 1 cut(s) | 588 |
| BbsI | GAAGAC | 1 cut(s) | 135 |
| Bbv12I | GWGCWC | 1 cut(s) | 1936 |
| BbvCI | CCTCAGC | 1 cut(s) | 1266 |
| BbvI | GCAGC | 4 cut(s) | 235, 754, 1258, 1391 |
| BccI | CCATC | 5 cut(s) | 116, 1046, 1175, 1660, 1939 |
| BceAI | ACGGC | 2 cut(s) | 98, 192 |
| BcgI | CGANNNNNNTGC | 2 cut(s) | 34, 68 |
| BciT130I | CCWGG | 4 cut(s) | 432, 900, 1065, 1353 |
| BciVI | GTATCC | 3 cut(s) | 1211, 1359, 1942 |
| BcoDI | GTCTC | 5 cut(s) | 90, 323, 917, 1232, 1322 |
| BfaI | CTAG | 3 cut(s) | 20, 848, 1502 |
| BfmI | CTRYAG | 2 cut(s) | 1272, 1430 |
| BfuAI | ACCTGC | 1 cut(s) | 553 |
| BfuI | GTATCC | 3 cut(s) | 1211, 1359, 1942 |
| BglII | AGATCT | 1 cut(s) | 556 |
| BisI | GCNGC | 5 cut(s) | 224, 303, 768, 1272, 1380 |
| BlsI | GCNGC | 5 cut(s) | 225, 304, 769, 1273, 1381 |
| Bme1390I | CCNGG | 4 cut(s) | 432, 900, 1065, 1353 |
| Bme18I | GGWCC | 3 cut(s) | 909, 1259, 1810 |
| BmgT120I | GGNCC | 3 cut(s) | 909, 1259, 1810 |
| BmiI | GGNNCC | 4 cut(s) | 600, 802, 911, 1875 |
| BmrFI | CCNGG | 4 cut(s) | 432, 900, 1065, 1353 |
| BmsI | GCATC | 3 cut(s) | 562, 652, 912 |
| BpiI | GAAGAC | 1 cut(s) | 135 |
| BpmI | CTGGAG | 3 cut(s) | 349, 1086, 1937 |
| Bpu10I | CCTNAGC | 3 cut(s) | 1266, 1340, 1935 |
| BpuEI | CTTGAG | 5 cut(s) | 717, 1415, 1512, 1587, 1676 |
| BsaBI | GATNNNNATC | 1 cut(s) | 1185 |
| BsaHI | GRCGYC | 1 cut(s) | 1056 |
| BsaI | GGTCTC | 1 cut(s) | 917 |
| BsaJI | CCNNGG | 7 cut(s) | 61, 184, 278, 431, 707, 898, 1239 |
| BsaWI | WCCGGW | 2 cut(s) | 906, 1333 |
| Bsc4I | CCNNNNNNNGG | 3 cut(s) | 713, 1214, 1300 |
| Bse1I | ACTGG | 3 cut(s) | 349, 1577, 1812 |
| Bse8I | GATNNNNATC | 1 cut(s) | 1185 |
| BseAI | TCCGGA | 1 cut(s) | 1333 |
| BseBI | CCWGG | 4 cut(s) | 432, 900, 1065, 1353 |
| BseDI | CCNNGG | 7 cut(s) | 61, 184, 278, 431, 707, 898, 1239 |
| BseGI | GGATG | 2 cut(s) | 903, 1657 |
| BseJI | GATNNNNATC | 1 cut(s) | 1185 |
| BseLI | CCNNNNNNNGG | 3 cut(s) | 713, 1214, 1300 |
| BseMII | CTCAG | 5 cut(s) | 831, 941, 1257, 1949, 1956 |
| BseNI | ACTGG | 3 cut(s) | 349, 1577, 1812 |
| BseXI | GCAGC | 4 cut(s) | 235, 754, 1258, 1391 |
| BsgI | GTGCAG | 1 cut(s) | 497 |
| Bsh1236I | CGCG | 2 cut(s) | 98, 1388 |
| BshFI | GGCC | 1 cut(s) | 126 |
| BsiHKAI | GWGCWC | 1 cut(s) | 1936 |
| BsiSI | CCGG | 3 cut(s) | 907, 1334, 1877 |
| BslFI | GGGAC | 2 cut(s) | 107, 895 |
| BslI | CCNNNNNNNGG | 3 cut(s) | 713, 1214, 1300 |
| BsmAI | GTCTC | 5 cut(s) | 90, 323, 917, 1232, 1322 |
| BsmBI | CGTCTC | 2 cut(s) | 90, 1232 |
| BsmFI | GGGAC | 2 cut(s) | 107, 895 |
| BsnI | GGCC | 1 cut(s) | 126 |
| Bso31I | GGTCTC | 1 cut(s) | 917 |
| Bsp1286I | GDGCHC | 1 cut(s) | 1936 |
| Bsp13I | TCCGGA | 1 cut(s) | 1333 |
| BspACI | CCGC | 2 cut(s) | 260, 303 |
| BspANI | GGCC | 1 cut(s) | 126 |
| BspCNI | CTCAG | 5 cut(s) | 832, 942, 1258, 1948, 1957 |
| BspEI | TCCGGA | 1 cut(s) | 1333 |
| BspFNI | CGCG | 2 cut(s) | 98, 1388 |
| BspLI | GGNNCC | 4 cut(s) | 600, 802, 911, 1875 |
| BspMAI | CTGCAG | 1 cut(s) | 1276 |
| BspMI | ACCTGC | 1 cut(s) | 553 |
| BspPI | GGATC | 5 cut(s) | 593, 606, 1311, 1868, 1881 |
| BspTNI | GGTCTC | 1 cut(s) | 917 |
| BsrI | ACTGG | 3 cut(s) | 349, 1577, 1812 |
| BssECI | CCNNGG | 7 cut(s) | 61, 184, 278, 431, 707, 898, 1239 |
| BssNI | GRCGYC | 1 cut(s) | 1056 |
| BssSI | CACGAG | 1 cut(s) | 588 |
| BssT1I | CCWWGG | 2 cut(s) | 61, 707 |
| Bst2BI | CACGAG | 1 cut(s) | 588 |
| Bst2UI | CCWGG | 4 cut(s) | 432, 900, 1065, 1353 |
| Bst4CI | ACNGT | 8 cut(s) | 524, 880, 996, 1223, 1434, 1465, 1665, 1954 |
| BstACI | GRCGYC | 1 cut(s) | 1056 |
| BstAPI | GCANNNNNTGC | 1 cut(s) | 1280 |
| BstC8I | GCNNGC | 3 cut(s) | 43, 73, 1384 |
| BstDEI | CTNAG | 8 cut(s) | 383, 840, 864, 950, 1266, 1340, 1935, 1965 |
| BstDSI | CCRYGG | 1 cut(s) | 184 |
| BstEII | GGTNACC | 1 cut(s) | 56 |
| BstENI | CCTNNNNNAGG | 1 cut(s) | 1298 |
| BstF5I | GGATG | 2 cut(s) | 903, 1657 |
| BstFNI | CGCG | 2 cut(s) | 98, 1388 |
| BstHHI | GCGC | 4 cut(s) | 77, 100, 1388, 1749 |
| BstMAI | GTCTC | 5 cut(s) | 90, 323, 917, 1232, 1322 |
| BstMWI | GCNNNNNNNGC | 6 cut(s) | 72, 865, 1271, 1280, 1385, 1846 |
| BstNI | CCWGG | 4 cut(s) | 432, 900, 1065, 1353 |
| BstPI | GGTNACC | 1 cut(s) | 56 |
| BstSCI | CCNGG | 4 cut(s) | 430, 898, 1063, 1351 |
| BstSFI | CTRYAG | 2 cut(s) | 1272, 1430 |
| BstUI | CGCG | 2 cut(s) | 98, 1388 |
| BstV1I | GCAGC | 4 cut(s) | 235, 754, 1258, 1391 |
| BstV2I | GAAGAC | 1 cut(s) | 135 |
| BstX2I | RGATCY | 4 cut(s) | 556, 598, 1303, 1873 |
| BstXI | CCANNNNNNTGG | 1 cut(s) | 1181 |
| BstYI | RGATCY | 4 cut(s) | 556, 598, 1303, 1873 |
| BsuI | GTATCC | 3 cut(s) | 1211, 1359, 1942 |
| BsuRI | GGCC | 1 cut(s) | 126 |
| BtgI | CCRYGG | 1 cut(s) | 184 |
| BtgZI | GCGATG | 1 cut(s) | 94 |
| BtsCI | GGATG | 2 cut(s) | 903, 1657 |
| BtsI | GCAGTG | 2 cut(s) | 256, 969 |
| BtsIMutI | CAGTG | 4 cut(s) | 256, 969, 1152, 1661 |
| BveI | ACCTGC | 1 cut(s) | 553 |
| Cac8I | GCNNGC | 3 cut(s) | 43, 73, 1384 |
| CfoI | GCGC | 4 cut(s) | 77, 100, 1388, 1749 |
| Cfr13I | GGNCC | 3 cut(s) | 909, 1259, 1810 |
| CseI | GACGC | 3 cut(s) | 104, 1045, 1377 |
| Csp6I | GTAC | 1 cut(s) | 657 |
| CviAII | CATG | 3 cut(s) | 760, 1006, 1289 |
| CviQI | GTAC | 1 cut(s) | 657 |
| DdeI | CTNAG | 8 cut(s) | 383, 840, 864, 950, 1266, 1340, 1935, 1965 |
| EaeI | YGGCCR | 1 cut(s) | 124 |
| Eco130I | CCWWGG | 2 cut(s) | 61, 707 |
| Eco31I | GGTCTC | 1 cut(s) | 917 |
| Eco47I | GGWCC | 3 cut(s) | 909, 1259, 1810 |
| Eco57I | CTGAAG | 1 cut(s) | 1319 |
| Eco91I | GGTNACC | 1 cut(s) | 56 |
| EcoNI | CCTNNNNNAGG | 1 cut(s) | 1298 |
| EcoO109I | RGGNCCY | 1 cut(s) | 1259 |
| EcoO65I | GGTNACC | 1 cut(s) | 56 |
| EcoRII | CCWGG | 4 cut(s) | 430, 898, 1063, 1351 |
| EcoT14I | CCWWGG | 2 cut(s) | 61, 707 |
| ErhI | CCWWGG | 2 cut(s) | 61, 707 |
| Esp3I | CGTCTC | 2 cut(s) | 90, 1232 |
| FaeI | CATG | 3 cut(s) | 763, 1009, 1292 |
| FalI | AAGNNNNNCTT | 4 cut(s) | 161, 193, 1032, 1064 |
| FaqI | GGGAC | 2 cut(s) | 107, 895 |
| FatI | CATG | 3 cut(s) | 759, 1005, 1288 |
| FblI | GTMKAC | 1 cut(s) | 1519 |
| Fnu4HI | GCNGC | 5 cut(s) | 224, 303, 768, 1272, 1380 |
| FokI | GGATG | 2 cut(s) | 890, 1644 |
| Fsp4HI | GCNGC | 5 cut(s) | 224, 303, 768, 1272, 1380 |
| FspBI | CTAG | 3 cut(s) | 20, 848, 1502 |
| FspI | TGCGCA | 1 cut(s) | 1748 |
| GlaI | GCGC | 4 cut(s) | 76, 99, 1387, 1748 |
| GluI | GCNGC | 5 cut(s) | 224, 303, 768, 1272, 1380 |
| GsuI | CTGGAG | 3 cut(s) | 349, 1086, 1937 |
| HaeIII | GGCC | 1 cut(s) | 126 |
| HapII | CCGG | 3 cut(s) | 907, 1334, 1877 |
| HgaI | GACGC | 3 cut(s) | 104, 1045, 1377 |
| HhaI | GCGC | 4 cut(s) | 77, 100, 1388, 1749 |
| Hin1I | GRCGYC | 1 cut(s) | 1056 |
| Hin1II | CATG | 3 cut(s) | 763, 1009, 1292 |
| Hin6I | GCGC | 4 cut(s) | 75, 98, 1386, 1747 |
| HinP1I | GCGC | 4 cut(s) | 75, 98, 1386, 1747 |
| HincII | GTYRAC | 9 cut(s) | 25, 409, 757, 1481, 1544, 1561, 1595, 1619, 1636 |
| HindII | GTYRAC | 9 cut(s) | 25, 409, 757, 1481, 1544, 1561, 1595, 1619, 1636 |
| HindIII | AAGCTT | 1 cut(s) | 1801 |
| HinfI | GANTC | 8 cut(s) | 7, 49, 624, 724, 952, 1235, 1330, 1682 |
| HpaII | CCGG | 3 cut(s) | 907, 1334, 1877 |
| HphI | GGTGA | 4 cut(s) | 68, 534, 1082, 1813 |
| Hpy99I | CGWCG | 3 cut(s) | 119, 122, 1227 |
| HpyAV | CCTTC | 5 cut(s) | 163, 284, 674, 1294, 1304 |
| HpyCH4III | ACNGT | 8 cut(s) | 524, 880, 996, 1223, 1434, 1465, 1665, 1954 |
| HpyCH4IV | ACGT | 1 cut(s) | 784 |
| HpyF10VI | GCNNNNNNNGC | 6 cut(s) | 72, 865, 1271, 1280, 1385, 1846 |
| HpyF3I | CTNAG | 8 cut(s) | 383, 840, 864, 950, 1266, 1340, 1935, 1965 |
| HpySE526I | ACGT | 1 cut(s) | 784 |
| Hsp92I | GRCGYC | 1 cut(s) | 1056 |
| Hsp92II | CATG | 3 cut(s) | 763, 1009, 1292 |
| HspAI | GCGC | 4 cut(s) | 75, 98, 1386, 1747 |
| Kpn2I | TCCGGA | 1 cut(s) | 1333 |
| LmnI | GCTCC | 4 cut(s) | 105, 506, 1210, 1336 |
| Lsp1109I | GCAGC | 4 cut(s) | 235, 754, 1258, 1391 |
| LweI | GCATC | 3 cut(s) | 562, 652, 912 |
| MaeI | CTAG | 3 cut(s) | 20, 848, 1502 |
| MaeII | ACGT | 1 cut(s) | 784 |
| MaeIII | GTNAC | 4 cut(s) | 56, 199, 1369, 1389 |
| MboII | GAAGA | 5 cut(s) | 135, 419, 1541, 1616, 1810 |
| MflI | RGATCY | 4 cut(s) | 556, 598, 1303, 1873 |
| MhlI | GDGCHC | 1 cut(s) | 1936 |
| MlsI | TGGCCA | 1 cut(s) | 126 |
| MluNI | TGGCCA | 1 cut(s) | 126 |
| MlyI | GAGTC | 4 cut(s) | 43, 633, 961, 1324 |
| MmeI | TCCRAC | 1 cut(s) | 626 |
| Mox20I | TGGCCA | 1 cut(s) | 126 |
| MroI | TCCGGA | 1 cut(s) | 1333 |
| MroXI | GAANNNNTTC | 3 cut(s) | 173, 287, 835 |
| MscI | TGGCCA | 1 cut(s) | 126 |
| MseI | TTAA | 4 cut(s) | 579, 744, 885, 918 |
| MslI | CAYNNNNRTG | 2 cut(s) | 356, 1050 |
| Msp20I | TGGCCA | 1 cut(s) | 126 |
| MspA1I | CMGCKG | 1 cut(s) | 305 |
| MspI | CCGG | 3 cut(s) | 907, 1334, 1877 |
| MspR9I | CCNGG | 4 cut(s) | 432, 900, 1065, 1353 |
| MvaI | CCWGG | 4 cut(s) | 432, 900, 1065, 1353 |
| MvnI | CGCG | 2 cut(s) | 98, 1388 |
| MwoI | GCNNNNNNNGC | 6 cut(s) | 72, 865, 1271, 1280, 1385, 1846 |
| NlaIII | CATG | 3 cut(s) | 763, 1009, 1292 |
| NlaIV | GGNNCC | 4 cut(s) | 600, 802, 911, 1875 |
| NmeAIII | GCCGAG | 2 cut(s) | 751, 1695 |
| NmuCI | GTSAC | 2 cut(s) | 56, 1389 |
| NsbI | TGCGCA | 1 cut(s) | 1748 |
| PaqCI | CACCTGC | 1 cut(s) | 553 |
| PdmI | GAANNNNTTC | 3 cut(s) | 173, 287, 835 |
| PfeI | GAWTC | 4 cut(s) | 7, 724, 1235, 1682 |
| PfoI | TCCNGGA | 1 cut(s) | 1063 |
| PkrI | GCNGC | 5 cut(s) | 225, 304, 769, 1273, 1381 |
| PleI | GAGTC | 4 cut(s) | 43, 632, 960, 1324 |
| PpsI | GAGTC | 4 cut(s) | 43, 632, 960, 1324 |
| PpuMI | RGGWCCY | 1 cut(s) | 1259 |
| Psp5II | RGGWCCY | 1 cut(s) | 1259 |
| Psp6I | CCWGG | 4 cut(s) | 430, 898, 1063, 1351 |
| PspEI | GGTNACC | 1 cut(s) | 56 |
| PspGI | CCWGG | 4 cut(s) | 430, 898, 1063, 1351 |
| PspN4I | GGNNCC | 4 cut(s) | 600, 802, 911, 1875 |
| PspPI | GGNCC | 3 cut(s) | 909, 1259, 1810 |
| PspPPI | RGGWCCY | 1 cut(s) | 1259 |
| PstI | CTGCAG | 1 cut(s) | 1276 |
| PsuI | RGATCY | 4 cut(s) | 556, 598, 1303, 1873 |
| RsaI | GTAC | 1 cut(s) | 658 |
| RsaNI | GTAC | 1 cut(s) | 657 |
| RseI | CAYNNNNRTG | 2 cut(s) | 356, 1050 |
| SaqAI | TTAA | 4 cut(s) | 579, 744, 885, 918 |
| SatI | GCNGC | 5 cut(s) | 224, 303, 768, 1272, 1380 |
| Sau96I | GGNCC | 3 cut(s) | 909, 1259, 1810 |
| SchI | GAGTC | 4 cut(s) | 43, 633, 961, 1324 |
| ScrFI | CCNGG | 4 cut(s) | 432, 900, 1065, 1353 |
| SduI | GDGCHC | 1 cut(s) | 1936 |
| SfaNI | GCATC | 3 cut(s) | 562, 652, 912 |
| SfcI | CTRYAG | 2 cut(s) | 1272, 1430 |
| SinI | GGWCC | 3 cut(s) | 909, 1259, 1810 |
| SmiMI | CAYNNNNRTG | 2 cut(s) | 356, 1050 |
| SmlI | CTYRAG | 5 cut(s) | 732, 1394, 1527, 1602, 1691 |
| SmoI | CTYRAG | 5 cut(s) | 732, 1394, 1527, 1602, 1691 |
| SsiI | CCGC | 2 cut(s) | 260, 303 |
| SspI | AATATT | 4 cut(s) | 531, 675, 791, 1122 |
| SspMI | CTAG | 3 cut(s) | 20, 848, 1502 |
| StyD4I | CCNGG | 4 cut(s) | 430, 898, 1063, 1351 |
| StyI | CCWWGG | 2 cut(s) | 61, 707 |
| TaaI | ACNGT | 8 cut(s) | 524, 880, 996, 1223, 1434, 1465, 1665, 1954 |
| TaiI | ACGT | 1 cut(s) | 787 |
| TauI | GCSGC | 1 cut(s) | 305 |
| TfiI | GAWTC | 4 cut(s) | 7, 724, 1235, 1682 |
| Tru1I | TTAA | 4 cut(s) | 579, 744, 885, 918 |
| Tru9I | TTAA | 4 cut(s) | 579, 744, 885, 918 |
| TscAI | CASTG | 4 cut(s) | 256, 976, 1152, 1668 |
| TseFI | GTSAC | 2 cut(s) | 56, 1389 |
| TseI | GCWGC | 4 cut(s) | 223, 767, 1271, 1379 |
| Tsp45I | GTSAC | 2 cut(s) | 56, 1389 |
| TspDTI | ATGAA | 5 cut(s) | 218, 368, 1044, 1277, 1695 |
| TspGWI | ACGGA | 3 cut(s) | 255, 1049, 1802 |
| TspRI | CASTG | 4 cut(s) | 256, 976, 1152, 1668 |
| VpaK11BI | GGWCC | 3 cut(s) | 909, 1259, 1810 |
| XagI | CCTNNNNNAGG | 1 cut(s) | 1298 |
| XapI | RAATTY | 1 cut(s) | 701 |
| XmiI | GTMKAC | 1 cut(s) | 1519 |
| XmnI | GAANNNNTTC | 3 cut(s) | 173, 287, 835 |
| XspI | CTAG | 3 cut(s) | 20, 848, 1502 |