FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3- polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin ferredoxin reductase system to COQ6
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| Species | Orthologous Gene IDs |
|---|---|
| arabidopsis_thaliana | AT3G24200 AT3G24200 |
| fragaria_vesca | FvH4_5g03680 FvH4_5g03680 FvH4_5g03680 |
| malus_domestica | MD06G1096300.v1.1 MD14G1116500.v1.1 |
| prunus_persica | Prupe.5G110900_v2.0.a1 |
| pyrus_communis | pycom06g09260 |
| rosa_chinensis | RchiOBHm_Chr7g0196051 |
| rosa_laevigata | RLG00000004070 |
| rosa_multiflora | Rmu_sc0001640.1_g000009 |
| rosa_roxburghii | Rroxscaffold_3G00259900 |
| rosa_rugosa | Rorug07G0029300 Rorug07G0029400 |
| rosa_samantha | Rh7AG156000 Rh7BG157700 Rh7CG161400 Rh7DG156900 |
| rosa_wichuraiana | Rw7G013330 |
| Enzyme | Recognition Site | Cut Count | Positions (bp) |
|---|---|---|---|
| AarI | CACCTGC | 1 cut(s) | 160 |
| Acc36I | ACCTGC | 3 cut(s) | 160, 253, 700 |
| AccBSI | CCGCTC | 1 cut(s) | 1183 |
| AccII | CGCG | 2 cut(s) | 1007, 1094 |
| AciI | CCGC | 2 cut(s) | 84, 1183 |
| AclWI | GGATC | 2 cut(s) | 122, 1350 |
| AcsI | RAATTY | 2 cut(s) | 797, 904 |
| AcvI | CACGTG | 1 cut(s) | 578 |
| AcyI | GRCGYC | 1 cut(s) | 956 |
| AfaI | GTAC | 6 cut(s) | 142, 299, 315, 354, 643, 1298 |
| AfiI | CCNNNNNNNGG | 2 cut(s) | 1061, 1314 |
| AflII | CTTAAG | 1 cut(s) | 1310 |
| AflIII | ACRYGT | 3 cut(s) | 577, 1005, 1092 |
| AjiI | CACGTC | 2 cut(s) | 242, 474 |
| AjnI | CCWGG | 1 cut(s) | 1215 |
| AjuI | GAANNNNNNNTTGG | 2 cut(s) | 908, 940 |
| AluBI | AGCT | 3 cut(s) | 511, 560, 1277 |
| AluI | AGCT | 3 cut(s) | 511, 560, 1277 |
| Alw21I | GWGCWC | 1 cut(s) | 1294 |
| Alw26I | GTCTC | 1 cut(s) | 1083 |
| AlwI | GGATC | 2 cut(s) | 122, 1350 |
| Ama87I | CYCGRG | 2 cut(s) | 457, 862 |
| AoxI | GGCC | 1 cut(s) | 698 |
| ApeKI | GCWGC | 3 cut(s) | 1037, 1274, 1277 |
| ApoI | RAATTY | 2 cut(s) | 797, 904 |
| Asp700I | GAANNNNTTC | 1 cut(s) | 1114 |
| AspLEI | GCGC | 1 cut(s) | 215 |
| AspS9I | GGNCC | 4 cut(s) | 567, 698, 839, 1253 |
| AsuHPI | GGTGA | 2 cut(s) | 734, 1043 |
| AvaI | CYCGRG | 2 cut(s) | 457, 862 |
| AvaII | GGWCC | 3 cut(s) | 567, 839, 1253 |
| BarI | GAAGNNNNNNTAC | 2 cut(s) | 392, 424 |
| BbrPI | CACGTG | 1 cut(s) | 578 |
| BbsI | GAAGAC | 2 cut(s) | 123, 407 |
| Bbv12I | GWGCWC | 1 cut(s) | 1294 |
| BbvCI | CCTCAGC | 1 cut(s) | 789 |
| BbvI | GCAGC | 3 cut(s) | 1049, 1264, 1286 |
| BccI | CCATC | 5 cut(s) | 74, 518, 557, 606, 1201 |
| BceAI | ACGGC | 1 cut(s) | 25 |
| BciT130I | CCWGG | 1 cut(s) | 1217 |
| BclI | TGATCA | 1 cut(s) | 253 |
| BcoDI | GTCTC | 1 cut(s) | 1083 |
| BfoI | RGCGCY | 1 cut(s) | 216 |
| BfrI | CTTAAG | 1 cut(s) | 1310 |
| BfuAI | ACCTGC | 3 cut(s) | 160, 253, 700 |
| BisI | GCNGC | 3 cut(s) | 1038, 1275, 1278 |
| BlpI | GCTNAGC | 1 cut(s) | 101 |
| BlsI | GCNGC | 3 cut(s) | 1039, 1276, 1279 |
| BmcAI | AGTACT | 2 cut(s) | 354, 1298 |
| Bme1390I | CCNGG | 1 cut(s) | 1217 |
| Bme18I | GGWCC | 3 cut(s) | 567, 839, 1253 |
| BmeT110I | CYCGRG | 2 cut(s) | 457, 862 |
| BmgBI | CACGTC | 2 cut(s) | 242, 474 |
| BmgT120I | GGNCC | 4 cut(s) | 567, 698, 839, 1253 |
| BmiI | GGNNCC | 2 cut(s) | 568, 1226 |
| BmrFI | CCNGG | 1 cut(s) | 1217 |
| BmsI | GCATC | 5 cut(s) | 114, 292, 978, 1024, 1343 |
| BpiI | GAAGAC | 2 cut(s) | 123, 407 |
| Bpu10I | CCTNAGC | 2 cut(s) | 283, 789 |
| Bpu1102I | GCTNAGC | 1 cut(s) | 101 |
| BsaAI | YACGTR | 1 cut(s) | 578 |
| BsaBI | GATNNNNATC | 2 cut(s) | 78, 1211 |
| BsaHI | GRCGYC | 1 cut(s) | 956 |
| BsaJI | CCNNGG | 5 cut(s) | 27, 131, 456, 861, 1149 |
| Bsc4I | CCNNNNNNNGG | 2 cut(s) | 1061, 1314 |
| Bse1I | ACTGG | 2 cut(s) | 283, 613 |
| Bse8I | GATNNNNATC | 2 cut(s) | 78, 1211 |
| BseBI | CCWGG | 1 cut(s) | 1217 |
| BseDI | CCNNGG | 5 cut(s) | 27, 131, 456, 861, 1149 |
| BseGI | GGATG | 3 cut(s) | 617, 799, 844 |
| BseJI | GATNNNNATC | 2 cut(s) | 78, 1211 |
| BseLI | CCNNNNNNNGG | 2 cut(s) | 1061, 1314 |
| BseMII | CTCAG | 1 cut(s) | 780 |
| BseNI | ACTGG | 2 cut(s) | 283, 613 |
| BseRI | GAGGAG | 1 cut(s) | 1330 |
| BseXI | GCAGC | 3 cut(s) | 1049, 1264, 1286 |
| BseYI | CCCAGC | 1 cut(s) | 695 |
| BsgI | GTGCAG | 1 cut(s) | 341 |
| Bsh1236I | CGCG | 2 cut(s) | 1007, 1094 |
| BshFI | GGCC | 1 cut(s) | 700 |
| BsiHKAI | GWGCWC | 1 cut(s) | 1294 |
| BsiHKCI | CYCGRG | 2 cut(s) | 457, 862 |
| BslFI | GGGAC | 1 cut(s) | 284 |
| BslI | CCNNNNNNNGG | 2 cut(s) | 1061, 1314 |
| BsmAI | GTCTC | 1 cut(s) | 1083 |
| BsmBI | CGTCTC | 1 cut(s) | 1083 |
| BsmFI | GGGAC | 1 cut(s) | 284 |
| BsmI | GAATGC | 2 cut(s) | 634, 1280 |
| BsnI | GGCC | 1 cut(s) | 700 |
| BsoBI | CYCGRG | 2 cut(s) | 457, 862 |
| Bsp1286I | GDGCHC | 1 cut(s) | 1294 |
| Bsp1407I | TGTACA | 1 cut(s) | 313 |
| Bsp143I | GATC | 4 cut(s) | 127, 253, 514, 1342 |
| Bsp1720I | GCTNAGC | 1 cut(s) | 101 |
| BspACI | CCGC | 2 cut(s) | 84, 1183 |
| BspANI | GGCC | 1 cut(s) | 700 |
| BspCNI | CTCAG | 1 cut(s) | 781 |
| BspFNI | CGCG | 2 cut(s) | 1007, 1094 |
| BspLI | GGNNCC | 2 cut(s) | 568, 1226 |
| BspMI | ACCTGC | 3 cut(s) | 160, 253, 700 |
| BspPI | GGATC | 2 cut(s) | 122, 1350 |
| BspTI | CTTAAG | 1 cut(s) | 1310 |
| BsrBI | CCGCTC | 1 cut(s) | 1183 |
| BsrGI | TGTACA | 1 cut(s) | 313 |
| BsrI | ACTGG | 2 cut(s) | 283, 613 |
| BssECI | CCNNGG | 5 cut(s) | 27, 131, 456, 861, 1149 |
| BssMI | GATC | 4 cut(s) | 127, 253, 514, 1342 |
| BssNI | GRCGYC | 1 cut(s) | 956 |
| BssT1I | CCWWGG | 2 cut(s) | 27, 131 |
| Bst2UI | CCWGG | 1 cut(s) | 1217 |
| Bst4CI | ACNGT | 7 cut(s) | 145, 362, 533, 646, 776, 1048, 1296 |
| Bst6I | CTCTTC | 1 cut(s) | 173 |
| BstACI | GRCGYC | 1 cut(s) | 956 |
| BstAFI | CTTAAG | 1 cut(s) | 1310 |
| BstAPI | GCANNNNNTGC | 1 cut(s) | 1145 |
| BstAUI | TGTACA | 1 cut(s) | 313 |
| BstBAI | YACGTR | 1 cut(s) | 578 |
| BstC8I | GCNNGC | 1 cut(s) | 993 |
| BstDEI | CTNAG | 5 cut(s) | 101, 283, 502, 789, 1365 |
| BstF5I | GGATG | 3 cut(s) | 617, 799, 844 |
| BstFNI | CGCG | 2 cut(s) | 1007, 1094 |
| BstH2I | RGCGCY | 1 cut(s) | 216 |
| BstHHI | GCGC | 1 cut(s) | 215 |
| BstKTI | GATC | 4 cut(s) | 130, 256, 517, 1345 |
| BstMAI | GTCTC | 1 cut(s) | 1083 |
| BstMBI | GATC | 4 cut(s) | 127, 253, 514, 1342 |
| BstMWI | GCNNNNNNNGC | 2 cut(s) | 1136, 1145 |
| BstNI | CCWGG | 1 cut(s) | 1217 |
| BstNSI | RCATGY | 2 cut(s) | 995, 1019 |
| BstSCI | CCNGG | 1 cut(s) | 1215 |
| BstUI | CGCG | 2 cut(s) | 1007, 1094 |
| BstV1I | GCAGC | 3 cut(s) | 1049, 1264, 1286 |
| BstV2I | GAAGAC | 2 cut(s) | 123, 407 |
| BsuRI | GGCC | 1 cut(s) | 700 |
| BtgZI | GCGATG | 1 cut(s) | 1047 |
| BtrI | CACGTC | 2 cut(s) | 242, 474 |
| BtsCI | GGATG | 3 cut(s) | 617, 799, 844 |
| BtsI | GCAGTG | 1 cut(s) | 1137 |
| BtsIMutI | CAGTG | 1 cut(s) | 1137 |
| BveI | ACCTGC | 3 cut(s) | 160, 253, 700 |
| Cac8I | GCNNGC | 1 cut(s) | 993 |
| CfoI | GCGC | 1 cut(s) | 215 |
| Cfr13I | GGNCC | 4 cut(s) | 567, 698, 839, 1253 |
| CseI | GACGC | 3 cut(s) | 945, 996, 1100 |
| Csp6I | GTAC | 6 cut(s) | 141, 298, 314, 353, 642, 1297 |
| CspCI | CAANNNNNGTGG | 4 cut(s) | 531, 566, 999, 1034 |
| CviAII | CATG | 5 cut(s) | 10, 375, 675, 992, 1016 |
| CviQI | GTAC | 6 cut(s) | 141, 298, 314, 353, 642, 1297 |
| DdeI | CTNAG | 5 cut(s) | 101, 283, 502, 789, 1365 |
| DpnI | GATC | 4 cut(s) | 129, 255, 516, 1344 |
| DpnII | GATC | 4 cut(s) | 127, 253, 514, 1342 |
| DraI | TTTAAA | 2 cut(s) | 892, 1260 |
| Eam1104I | CTCTTC | 1 cut(s) | 173 |
| EarI | CTCTTC | 1 cut(s) | 173 |
| Eco130I | CCWWGG | 2 cut(s) | 27, 131 |
| Eco47I | GGWCC | 3 cut(s) | 567, 839, 1253 |
| Eco72I | CACGTG | 1 cut(s) | 578 |
| Eco88I | CYCGRG | 2 cut(s) | 457, 862 |
| EcoRII | CCWGG | 1 cut(s) | 1215 |
| EcoT14I | CCWWGG | 2 cut(s) | 27, 131 |
| EcoT22I | ATGCAT | 1 cut(s) | 993 |
| ErhI | CCWWGG | 2 cut(s) | 27, 131 |
| Esp3I | CGTCTC | 1 cut(s) | 1083 |
| FaeI | CATG | 5 cut(s) | 13, 378, 678, 995, 1019 |
| FaqI | GGGAC | 1 cut(s) | 284 |
| FatI | CATG | 5 cut(s) | 9, 374, 674, 991, 1015 |
| FauI | CCCGC | 1 cut(s) | 91 |
| FbaI | TGATCA | 1 cut(s) | 253 |
| Fnu4HI | GCNGC | 3 cut(s) | 1038, 1275, 1278 |
| FokI | GGATG | 3 cut(s) | 624, 806, 831 |
| Fsp4HI | GCNGC | 3 cut(s) | 1038, 1275, 1278 |
| GlaI | GCGC | 1 cut(s) | 214 |
| GluI | GCNGC | 3 cut(s) | 1038, 1275, 1278 |
| GsaI | CCCAGC | 1 cut(s) | 699 |
| HaeII | RGCGCY | 1 cut(s) | 216 |
| HaeIII | GGCC | 1 cut(s) | 700 |
| HgaI | GACGC | 3 cut(s) | 945, 996, 1100 |
| HhaI | GCGC | 1 cut(s) | 215 |
| Hin1I | GRCGYC | 1 cut(s) | 956 |
| Hin1II | CATG | 5 cut(s) | 13, 378, 678, 995, 1019 |
| Hin6I | GCGC | 1 cut(s) | 213 |
| HinP1I | GCGC | 1 cut(s) | 213 |
| HincII | GTYRAC | 1 cut(s) | 45 |
| HindII | GTYRAC | 1 cut(s) | 45 |
| HindIII | AAGCTT | 1 cut(s) | 509 |
| HinfI | GANTC | 2 cut(s) | 323, 1110 |
| HphI | GGTGA | 2 cut(s) | 734, 1043 |
| Hpy166II | GTNNAC | 4 cut(s) | 45, 426, 842, 1051 |
| Hpy188I | TCNGA | 2 cut(s) | 961, 1120 |
| Hpy188III | TCNNGA | 9 cut(s) | 109, 397, 417, 480, 824, 864, 1107, 1201, 1228 |
| Hpy8I | GTNNAC | 4 cut(s) | 45, 426, 842, 1051 |
| HpyAV | CCTTC | 2 cut(s) | 423, 1225 |
| HpyCH4III | ACNGT | 7 cut(s) | 145, 362, 533, 646, 776, 1048, 1296 |
| HpyCH4IV | ACGT | 3 cut(s) | 241, 473, 577 |
| HpyF10VI | GCNNNNNNNGC | 2 cut(s) | 1136, 1145 |
| HpyF3I | CTNAG | 5 cut(s) | 101, 283, 502, 789, 1365 |
| HpySE526I | ACGT | 3 cut(s) | 241, 473, 577 |
| Hsp92I | GRCGYC | 1 cut(s) | 956 |
| Hsp92II | CATG | 5 cut(s) | 13, 378, 678, 995, 1019 |
| HspAI | GCGC | 1 cut(s) | 213 |
| Ksp22I | TGATCA | 1 cut(s) | 253 |
| Kzo9I | GATC | 4 cut(s) | 127, 253, 514, 1342 |
| LmnI | GCTCC | 3 cut(s) | 557, 1136, 1289 |
| Lsp1109I | GCAGC | 3 cut(s) | 1049, 1264, 1286 |
| LweI | GCATC | 5 cut(s) | 114, 292, 978, 1024, 1343 |
| MaeII | ACGT | 3 cut(s) | 241, 473, 577 |
| MaeIII | GTNAC | 4 cut(s) | 145, 573, 617, 1198 |
| MalI | GATC | 4 cut(s) | 129, 255, 516, 1344 |
| MbiI | CCGCTC | 1 cut(s) | 1183 |
| MboI | GATC | 4 cut(s) | 127, 253, 514, 1342 |
| MboII | GAAGA | 4 cut(s) | 128, 160, 412, 1177 |
| MfeI | CAATTG | 2 cut(s) | 53, 702 |
| MhlI | GDGCHC | 1 cut(s) | 1294 |
| MluI | ACGCGT | 2 cut(s) | 1005, 1092 |
| MmeI | TCCRAC | 1 cut(s) | 535 |
| MnlI | CCTC | 8 cut(s) | 466, 784, 860, 866, 871, 1114, 1144, 1308 |
| Mph1103I | ATGCAT | 1 cut(s) | 993 |
| MroXI | GAANNNNTTC | 1 cut(s) | 1114 |
| MseI | TTAA | 6 cut(s) | 600, 782, 891, 1074, 1259, 1311 |
| MslI | CAYNNNNRTG | 1 cut(s) | 1205 |
| MspA1I | CMGCKG | 1 cut(s) | 1277 |
| MspCI | CTTAAG | 1 cut(s) | 1310 |
| MspR9I | CCNGG | 1 cut(s) | 1217 |
| MunI | CAATTG | 2 cut(s) | 53, 702 |
| Mva1269I | GAATGC | 2 cut(s) | 634, 1280 |
| MvaI | CCWGG | 1 cut(s) | 1217 |
| MvnI | CGCG | 2 cut(s) | 1007, 1094 |
| MwoI | GCNNNNNNNGC | 2 cut(s) | 1136, 1145 |
| NdeII | GATC | 4 cut(s) | 127, 253, 514, 1342 |
| NlaIII | CATG | 5 cut(s) | 13, 378, 678, 995, 1019 |
| NlaIV | GGNNCC | 2 cut(s) | 568, 1226 |
| NmeAIII | GCCGAG | 1 cut(s) | 1174 |
| NmuCI | GTSAC | 2 cut(s) | 573, 1198 |
| NsiI | ATGCAT | 1 cut(s) | 993 |
| NspI | RCATGY | 2 cut(s) | 995, 1019 |
| PaeI | GCATGC | 1 cut(s) | 995 |
| PaqCI | CACCTGC | 1 cut(s) | 160 |
| PctI | GAATGC | 2 cut(s) | 634, 1280 |
| PdmI | GAANNNNTTC | 1 cut(s) | 1114 |
| PfeI | GAWTC | 2 cut(s) | 323, 1110 |
| PfoI | TCCNGGA | 1 cut(s) | 1215 |
| PkrI | GCNGC | 3 cut(s) | 1039, 1276, 1279 |
| PmaCI | CACGTG | 1 cut(s) | 578 |
| PmlI | CACGTG | 1 cut(s) | 578 |
| Ppu21I | YACGTR | 1 cut(s) | 578 |
| Psp6I | CCWGG | 1 cut(s) | 1215 |
| PspCI | CACGTG | 1 cut(s) | 578 |
| PspFI | CCCAGC | 1 cut(s) | 695 |
| PspGI | CCWGG | 1 cut(s) | 1215 |
| PspN4I | GGNNCC | 2 cut(s) | 568, 1226 |
| PspPI | GGNCC | 4 cut(s) | 567, 698, 839, 1253 |
| PvuII | CAGCTG | 1 cut(s) | 1277 |
| RsaI | GTAC | 6 cut(s) | 142, 299, 315, 354, 643, 1298 |
| RsaNI | GTAC | 6 cut(s) | 141, 298, 314, 353, 642, 1297 |
| RseI | CAYNNNNRTG | 1 cut(s) | 1205 |
| SaqAI | TTAA | 6 cut(s) | 600, 782, 891, 1074, 1259, 1311 |
| SatI | GCNGC | 3 cut(s) | 1038, 1275, 1278 |
| Sau3AI | GATC | 4 cut(s) | 127, 253, 514, 1342 |
| Sau96I | GGNCC | 4 cut(s) | 567, 698, 839, 1253 |
| ScaI | AGTACT | 2 cut(s) | 354, 1298 |
| ScrFI | CCNGG | 1 cut(s) | 1217 |
| SduI | GDGCHC | 1 cut(s) | 1294 |
| SfaNI | GCATC | 5 cut(s) | 114, 292, 978, 1024, 1343 |
| SinI | GGWCC | 3 cut(s) | 567, 839, 1253 |
| SmiMI | CAYNNNNRTG | 1 cut(s) | 1205 |
| SmlI | CTYRAG | 1 cut(s) | 1310 |
| SmoI | CTYRAG | 1 cut(s) | 1310 |
| SphI | GCATGC | 1 cut(s) | 995 |
| SsiI | CCGC | 2 cut(s) | 84, 1183 |
| SspI | AATATT | 1 cut(s) | 739 |
| StyD4I | CCNGG | 1 cut(s) | 1215 |
| StyI | CCWWGG | 2 cut(s) | 27, 131 |
| TaaI | ACNGT | 7 cut(s) | 145, 362, 533, 646, 776, 1048, 1296 |
| TaiI | ACGT | 3 cut(s) | 244, 476, 580 |
| TaqI | TCGA | 2 cut(s) | 186, 648 |
| TaqII | GACCGA | 1 cut(s) | 1241 |
| TatI | WGTACW | 5 cut(s) | 140, 313, 352, 641, 1296 |
| TfiI | GAWTC | 2 cut(s) | 323, 1110 |
| Tru1I | TTAA | 6 cut(s) | 600, 782, 891, 1074, 1259, 1311 |
| Tru9I | TTAA | 6 cut(s) | 600, 782, 891, 1074, 1259, 1311 |
| TscAI | CASTG | 1 cut(s) | 1137 |
| TseFI | GTSAC | 2 cut(s) | 573, 1198 |
| TseI | GCWGC | 3 cut(s) | 1037, 1274, 1277 |
| Tsp45I | GTSAC | 2 cut(s) | 573, 1198 |
| TspDTI | ATGAA | 3 cut(s) | 767, 810, 1317 |
| TspGWI | ACGGA | 1 cut(s) | 1231 |
| TspRI | CASTG | 1 cut(s) | 1137 |
| Vha464I | CTTAAG | 1 cut(s) | 1310 |
| VpaK11BI | GGWCC | 3 cut(s) | 567, 839, 1253 |
| XapI | RAATTY | 2 cut(s) | 797, 904 |
| XceI | RCATGY | 2 cut(s) | 995, 1019 |
| XmnI | GAANNNNTTC | 1 cut(s) | 1114 |
| ZrmI | AGTACT | 2 cut(s) | 354, 1298 |
| Zsp2I | ATGCAT | 1 cut(s) | 993 |