FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3- polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin ferredoxin reductase system to COQ6
Download the Full Tree (.nwk) file, then upload it to any of the following tools to customize colors, fonts, annotations, clades, and branch support.
| Species | Orthologous Gene IDs |
|---|---|
| arabidopsis_thaliana | AT3G24200 AT3G24200 |
| fragaria_vesca | FvH4_5g03680 FvH4_5g03680 FvH4_5g03680 |
| malus_domestica | MD06G1096300.v1.1 MD14G1116500.v1.1 |
| prunus_persica | Prupe.5G110900_v2.0.a1 |
| pyrus_communis | pycom06g09260 |
| rosa_chinensis | RchiOBHm_Chr7g0196051 |
| rosa_laevigata | RLG00000004070 |
| rosa_multiflora | Rmu_sc0001640.1_g000009 |
| rosa_roxburghii | Rroxscaffold_3G00259900 |
| rosa_rugosa | Rorug07G0029300 Rorug07G0029400 |
| rosa_samantha | Rh7AG156000 Rh7BG157700 Rh7CG161400 Rh7DG156900 |
| rosa_wichuraiana | Rw7G013330 |
| Enzyme | Recognition Site | Cut Count | Positions (bp) |
|---|---|---|---|
| AarI | CACCTGC | 1 cut(s) | 352 |
| Acc16I | TGCGCA | 1 cut(s) | 835 |
| Acc36I | ACCTGC | 2 cut(s) | 352, 415 |
| AccB1I | GGYRCC | 1 cut(s) | 107 |
| AccII | CGCG | 1 cut(s) | 1350 |
| AccIII | TCCGGA | 1 cut(s) | 919 |
| AciI | CCGC | 1 cut(s) | 1013 |
| AclWI | GGATC | 2 cut(s) | 684, 1428 |
| AcoI | YGGCCR | 1 cut(s) | 255 |
| AcvI | CACGTG | 1 cut(s) | 740 |
| AfaI | GTAC | 4 cut(s) | 73, 334, 477, 1376 |
| AfiI | CCNNNNNNNGG | 2 cut(s) | 1139, 1392 |
| AflIII | ACRYGT | 1 cut(s) | 739 |
| AjnI | CCWGG | 1 cut(s) | 604 |
| AluBI | AGCT | 6 cut(s) | 9, 25, 83, 99, 212, 722 |
| AluI | AGCT | 6 cut(s) | 9, 25, 83, 99, 212, 722 |
| Alw21I | GWGCWC | 1 cut(s) | 1372 |
| AlwI | GGATC | 2 cut(s) | 684, 1428 |
| Aor13HI | TCCGGA | 1 cut(s) | 919 |
| AoxI | GGCC | 2 cut(s) | 204, 255 |
| ApeKI | GCWGC | 7 cut(s) | 80, 83, 136, 517, 1115, 1352, 1355 |
| Asp700I | GAANNNNTTC | 1 cut(s) | 1192 |
| AspLEI | GCGC | 2 cut(s) | 836, 1352 |
| AspS9I | GGNCC | 4 cut(s) | 205, 729, 860, 1331 |
| AsuHPI | GGTGA | 2 cut(s) | 896, 1121 |
| AvaII | GGWCC | 3 cut(s) | 729, 860, 1331 |
| BaeGI | GKGCMC | 1 cut(s) | 112 |
| BalI | TGGCCA | 1 cut(s) | 257 |
| BanI | GGYRCC | 1 cut(s) | 107 |
| BarI | GAAGNNNNNNTAC | 2 cut(s) | 554, 586 |
| BbrPI | CACGTG | 1 cut(s) | 740 |
| BbsI | GAAGAC | 2 cut(s) | 315, 569 |
| Bbv12I | GWGCWC | 1 cut(s) | 1372 |
| BbvI | GCAGC | 7 cut(s) | 70, 92, 148, 504, 1127, 1339, 1342 |
| BccI | CCATC | 6 cut(s) | 266, 680, 719, 768, 1279, 1292 |
| BceAI | ACGGC | 1 cut(s) | 1284 |
| BciT130I | CCWGG | 1 cut(s) | 606 |
| BciVI | GTATCC | 1 cut(s) | 541 |
| BclI | TGATCA | 3 cut(s) | 12, 124, 415 |
| BfaI | CTAG | 4 cut(s) | 209, 225, 468, 1295 |
| BfuAI | ACCTGC | 2 cut(s) | 352, 415 |
| BfuI | GTATCC | 1 cut(s) | 541 |
| BisI | GCNGC | 7 cut(s) | 81, 84, 137, 518, 1116, 1353, 1356 |
| BlsI | GCNGC | 7 cut(s) | 82, 85, 138, 519, 1117, 1354, 1357 |
| Bme1390I | CCNGG | 1 cut(s) | 606 |
| Bme18I | GGWCC | 3 cut(s) | 729, 860, 1331 |
| BmgT120I | GGNCC | 4 cut(s) | 205, 729, 860, 1331 |
| BmiI | GGNNCC | 2 cut(s) | 109, 730 |
| BmrFI | CCNGG | 1 cut(s) | 606 |
| BpiI | GAAGAC | 2 cut(s) | 315, 569 |
| Bpu10I | CCTNAGC | 1 cut(s) | 445 |
| Bsa29I | ATCGAT | 1 cut(s) | 829 |
| BsaAI | YACGTR | 1 cut(s) | 740 |
| BsaBI | GATNNNNATC | 2 cut(s) | 270, 1289 |
| BsaJI | CCNNGG | 2 cut(s) | 219, 1363 |
| BsaWI | WCCGGW | 2 cut(s) | 857, 919 |
| BsaXI | ACNNNNNCTCC | 2 cut(s) | 180, 210 |
| Bsc4I | CCNNNNNNNGG | 2 cut(s) | 1139, 1392 |
| Bse1I | ACTGG | 3 cut(s) | 79, 678, 775 |
| Bse3DI | GCAATG | 3 cut(s) | 127, 171, 1203 |
| Bse8I | GATNNNNATC | 2 cut(s) | 270, 1289 |
| BseAI | TCCGGA | 1 cut(s) | 919 |
| BseBI | CCWGG | 1 cut(s) | 606 |
| BseCI | ATCGAT | 1 cut(s) | 829 |
| BseDI | CCNNGG | 2 cut(s) | 219, 1363 |
| BseGI | GGATG | 3 cut(s) | 630, 779, 961 |
| BseJI | GATNNNNATC | 2 cut(s) | 270, 1289 |
| BseLI | CCNNNNNNNGG | 2 cut(s) | 1139, 1392 |
| BseMI | GCAATG | 3 cut(s) | 127, 171, 1203 |
| BseMII | CTCAG | 3 cut(s) | 1188, 1218, 1332 |
| BseNI | ACTGG | 3 cut(s) | 79, 678, 775 |
| BseRI | GAGGAG | 1 cut(s) | 201 |
| BseSI | GKGCMC | 1 cut(s) | 112 |
| BseXI | GCAGC | 7 cut(s) | 70, 92, 148, 504, 1127, 1339, 1342 |
| BseYI | CCCAGC | 1 cut(s) | 1139 |
| BsgI | GTGCAG | 2 cut(s) | 99, 503 |
| Bsh1236I | CGCG | 1 cut(s) | 1350 |
| BshFI | GGCC | 2 cut(s) | 206, 257 |
| BshNI | GGYRCC | 1 cut(s) | 107 |
| BshVI | ATCGAT | 1 cut(s) | 829 |
| BsiHKAI | GWGCWC | 1 cut(s) | 1372 |
| BsiSI | CCGG | 2 cut(s) | 858, 920 |
| BslFI | GGGAC | 1 cut(s) | 446 |
| BslI | CCNNNNNNNGG | 2 cut(s) | 1139, 1392 |
| BsmFI | GGGAC | 1 cut(s) | 446 |
| BsmI | GAATGC | 5 cut(s) | 234, 609, 796, 1004, 1358 |
| BsnI | GGCC | 2 cut(s) | 206, 257 |
| Bsp1286I | GDGCHC | 2 cut(s) | 112, 1372 |
| Bsp13I | TCCGGA | 1 cut(s) | 919 |
| Bsp1407I | TGTACA | 1 cut(s) | 475 |
| Bsp143I | GATC | 5 cut(s) | 12, 124, 415, 676, 1420 |
| BspACI | CCGC | 1 cut(s) | 1013 |
| BspANI | GGCC | 2 cut(s) | 206, 257 |
| BspCNI | CTCAG | 3 cut(s) | 1189, 1219, 1331 |
| BspDI | ATCGAT | 1 cut(s) | 829 |
| BspEI | TCCGGA | 1 cut(s) | 919 |
| BspFNI | CGCG | 1 cut(s) | 1350 |
| BspLI | GGNNCC | 2 cut(s) | 109, 730 |
| BspMI | ACCTGC | 2 cut(s) | 352, 415 |
| BspPI | GGATC | 2 cut(s) | 684, 1428 |
| BspT107I | GGYRCC | 1 cut(s) | 107 |
| BsrDI | GCAATG | 3 cut(s) | 127, 171, 1203 |
| BsrGI | TGTACA | 1 cut(s) | 475 |
| BsrI | ACTGG | 3 cut(s) | 79, 678, 775 |
| BssECI | CCNNGG | 2 cut(s) | 219, 1363 |
| BssMI | GATC | 5 cut(s) | 12, 124, 415, 676, 1420 |
| BssT1I | CCWWGG | 1 cut(s) | 219 |
| Bst2UI | CCWGG | 1 cut(s) | 606 |
| Bst4CI | ACNGT | 7 cut(s) | 165, 337, 524, 808, 938, 1126, 1374 |
| Bst6I | CTCTTC | 1 cut(s) | 365 |
| BstAUI | TGTACA | 1 cut(s) | 475 |
| BstBAI | YACGTR | 1 cut(s) | 740 |
| BstC8I | GCNNGC | 2 cut(s) | 542, 1071 |
| BstDEI | CTNAG | 6 cut(s) | 445, 664, 680, 1197, 1227, 1318 |
| BstDSI | CCRYGG | 1 cut(s) | 1363 |
| BstF5I | GGATG | 3 cut(s) | 630, 779, 961 |
| BstFNI | CGCG | 1 cut(s) | 1350 |
| BstHHI | GCGC | 2 cut(s) | 836, 1352 |
| BstKTI | GATC | 5 cut(s) | 15, 127, 418, 679, 1423 |
| BstMBI | GATC | 5 cut(s) | 12, 124, 415, 676, 1420 |
| BstMWI | GCNNNNNNNGC | 1 cut(s) | 198 |
| BstNI | CCWGG | 1 cut(s) | 606 |
| BstNSI | RCATGY | 4 cut(s) | 407, 544, 1073, 1097 |
| BstSCI | CCNGG | 1 cut(s) | 604 |
| BstSLI | GKGCMC | 1 cut(s) | 112 |
| BstUI | CGCG | 1 cut(s) | 1350 |
| BstV1I | GCAGC | 7 cut(s) | 70, 92, 148, 504, 1127, 1339, 1342 |
| BstV2I | GAAGAC | 2 cut(s) | 315, 569 |
| BstX2I | RGATCY | 1 cut(s) | 676 |
| BstYI | RGATCY | 1 cut(s) | 676 |
| Bsu15I | ATCGAT | 1 cut(s) | 829 |
| BsuI | GTATCC | 1 cut(s) | 541 |
| BsuRI | GGCC | 2 cut(s) | 206, 257 |
| BsuTUI | ATCGAT | 1 cut(s) | 829 |
| BtgI | CCRYGG | 1 cut(s) | 1363 |
| BtgZI | GCGATG | 1 cut(s) | 1125 |
| BtsCI | GGATG | 3 cut(s) | 630, 779, 961 |
| BtsI | GCAGTG | 1 cut(s) | 1215 |
| BtsIMutI | CAGTG | 2 cut(s) | 1122, 1215 |
| BveI | ACCTGC | 2 cut(s) | 352, 415 |
| Cac8I | GCNNGC | 2 cut(s) | 542, 1071 |
| CfoI | GCGC | 2 cut(s) | 836, 1352 |
| Cfr13I | GGNCC | 4 cut(s) | 205, 729, 860, 1331 |
| ClaI | ATCGAT | 1 cut(s) | 829 |
| Csp6I | GTAC | 4 cut(s) | 72, 333, 476, 1375 |
| CspCI | CAANNNNNGTGG | 4 cut(s) | 693, 728, 1077, 1112 |
| CviQI | GTAC | 4 cut(s) | 72, 333, 476, 1375 |
| DdeI | CTNAG | 6 cut(s) | 445, 664, 680, 1197, 1227, 1318 |
| DpnI | GATC | 5 cut(s) | 14, 126, 417, 678, 1422 |
| DpnII | GATC | 5 cut(s) | 12, 124, 415, 676, 1420 |
| DraI | TTTAAA | 2 cut(s) | 600, 1338 |
| EaeI | YGGCCR | 1 cut(s) | 255 |
| Eam1104I | CTCTTC | 1 cut(s) | 365 |
| EarI | CTCTTC | 1 cut(s) | 365 |
| EciI | GGCGGA | 1 cut(s) | 1002 |
| Eco130I | CCWWGG | 1 cut(s) | 219 |
| Eco47I | GGWCC | 3 cut(s) | 729, 860, 1331 |
| Eco72I | CACGTG | 1 cut(s) | 740 |
| EcoRII | CCWGG | 1 cut(s) | 604 |
| EcoT14I | CCWWGG | 1 cut(s) | 219 |
| EcoT22I | ATGCAT | 6 cut(s) | 40, 409, 542, 1071, 1174, 1414 |
| ErhI | CCWWGG | 1 cut(s) | 219 |
| FaqI | GGGAC | 1 cut(s) | 446 |
| FauNDI | CATATG | 1 cut(s) | 1408 |
| FbaI | TGATCA | 3 cut(s) | 12, 124, 415 |
| Fnu4HI | GCNGC | 7 cut(s) | 81, 84, 137, 518, 1116, 1353, 1356 |
| FokI | GGATG | 3 cut(s) | 637, 786, 968 |
| Fsp4HI | GCNGC | 7 cut(s) | 81, 84, 137, 518, 1116, 1353, 1356 |
| FspAI | RTGCGCAY | 1 cut(s) | 835 |
| FspBI | CTAG | 4 cut(s) | 209, 225, 468, 1295 |
| FspI | TGCGCA | 1 cut(s) | 835 |
| GlaI | GCGC | 2 cut(s) | 835, 1351 |
| GluI | GCNGC | 7 cut(s) | 81, 84, 137, 518, 1116, 1353, 1356 |
| GsaI | CCCAGC | 1 cut(s) | 1143 |
| HaeIII | GGCC | 2 cut(s) | 206, 257 |
| HapII | CCGG | 2 cut(s) | 858, 920 |
| HhaI | GCGC | 2 cut(s) | 836, 1352 |
| Hin6I | GCGC | 2 cut(s) | 834, 1350 |
| HinP1I | GCGC | 2 cut(s) | 834, 1350 |
| HinfI | GANTC | 4 cut(s) | 291, 649, 916, 1188 |
| HpaII | CCGG | 2 cut(s) | 858, 920 |
| HphI | GGTGA | 2 cut(s) | 896, 1121 |
| Hpy166II | GTNNAC | 1 cut(s) | 1129 |
| Hpy188I | TCNGA | 5 cut(s) | 17, 1039, 1198, 1228, 1425 |
| Hpy188III | TCNNGA | 6 cut(s) | 301, 559, 579, 920, 1185, 1306 |
| Hpy8I | GTNNAC | 1 cut(s) | 1129 |
| HpyAV | CCTTC | 2 cut(s) | 244, 585 |
| HpyCH4III | ACNGT | 7 cut(s) | 165, 337, 524, 808, 938, 1126, 1374 |
| HpyCH4IV | ACGT | 1 cut(s) | 739 |
| HpyF10VI | GCNNNNNNNGC | 1 cut(s) | 198 |
| HpyF3I | CTNAG | 6 cut(s) | 445, 664, 680, 1197, 1227, 1318 |
| HpySE526I | ACGT | 1 cut(s) | 739 |
| HspAI | GCGC | 2 cut(s) | 834, 1350 |
| Kpn2I | TCCGGA | 1 cut(s) | 919 |
| Ksp22I | TGATCA | 3 cut(s) | 12, 124, 415 |
| Kzo9I | GATC | 5 cut(s) | 12, 124, 415, 676, 1420 |
| LmnI | GCTCC | 3 cut(s) | 104, 719, 1367 |
| Lsp1109I | GCAGC | 7 cut(s) | 70, 92, 148, 504, 1127, 1339, 1342 |
| MaeI | CTAG | 4 cut(s) | 209, 225, 468, 1295 |
| MaeII | ACGT | 1 cut(s) | 739 |
| MaeIII | GTNAC | 4 cut(s) | 337, 735, 896, 1276 |
| MalI | GATC | 5 cut(s) | 14, 126, 417, 678, 1422 |
| MboI | GATC | 5 cut(s) | 12, 124, 415, 676, 1420 |
| MboII | GAAGA | 7 cut(s) | 30, 138, 320, 352, 574, 935, 1255 |
| MfeI | CAATTG | 1 cut(s) | 864 |
| MflI | RGATCY | 1 cut(s) | 676 |
| MhlI | GDGCHC | 2 cut(s) | 112, 1372 |
| MlsI | TGGCCA | 1 cut(s) | 257 |
| MluCI | AATT | 5 cut(s) | 749, 864, 889, 1104, 1234 |
| MluNI | TGGCCA | 1 cut(s) | 257 |
| MlyI | GAGTC | 1 cut(s) | 285 |
| MmeI | TCCRAC | 2 cut(s) | 163, 697 |
| MnlI | CCTC | 7 cut(s) | 179, 182, 598, 946, 1192, 1222, 1302 |
| Mox20I | TGGCCA | 1 cut(s) | 257 |
| Mph1103I | ATGCAT | 6 cut(s) | 40, 409, 542, 1071, 1174, 1414 |
| MroI | TCCGGA | 1 cut(s) | 919 |
| MroXI | GAANNNNTTC | 1 cut(s) | 1192 |
| MscI | TGGCCA | 1 cut(s) | 257 |
| MseI | TTAA | 5 cut(s) | 599, 762, 1152, 1337, 1389 |
| MslI | CAYNNNNRTG | 2 cut(s) | 402, 1208 |
| Msp20I | TGGCCA | 1 cut(s) | 257 |
| MspA1I | CMGCKG | 1 cut(s) | 83 |
| MspI | CCGG | 2 cut(s) | 858, 920 |
| MspR9I | CCNGG | 1 cut(s) | 606 |
| MunI | CAATTG | 1 cut(s) | 864 |
| Mva1269I | GAATGC | 5 cut(s) | 234, 609, 796, 1004, 1358 |
| MvaI | CCWGG | 1 cut(s) | 606 |
| MvnI | CGCG | 1 cut(s) | 1350 |
| MwoI | GCNNNNNNNGC | 1 cut(s) | 198 |
| NdeI | CATATG | 1 cut(s) | 1408 |
| NdeII | GATC | 5 cut(s) | 12, 124, 415, 676, 1420 |
| NlaIV | GGNNCC | 2 cut(s) | 109, 730 |
| NmuCI | GTSAC | 1 cut(s) | 735 |
| NsbI | TGCGCA | 1 cut(s) | 835 |
| NsiI | ATGCAT | 6 cut(s) | 40, 409, 542, 1071, 1174, 1414 |
| NspI | RCATGY | 4 cut(s) | 407, 544, 1073, 1097 |
| PaeI | GCATGC | 2 cut(s) | 544, 1073 |
| PaqCI | CACCTGC | 1 cut(s) | 352 |
| PctI | GAATGC | 5 cut(s) | 234, 609, 796, 1004, 1358 |
| PdmI | GAANNNNTTC | 1 cut(s) | 1192 |
| PfeI | GAWTC | 3 cut(s) | 649, 916, 1188 |
| PkrI | GCNGC | 7 cut(s) | 82, 85, 138, 519, 1117, 1354, 1357 |
| PleI | GAGTC | 1 cut(s) | 285 |
| PmaCI | CACGTG | 1 cut(s) | 740 |
| PmlI | CACGTG | 1 cut(s) | 740 |
| PpsI | GAGTC | 1 cut(s) | 285 |
| Ppu21I | YACGTR | 1 cut(s) | 740 |
| Psp6I | CCWGG | 1 cut(s) | 604 |
| PspCI | CACGTG | 1 cut(s) | 740 |
| PspFI | CCCAGC | 1 cut(s) | 1139 |
| PspGI | CCWGG | 1 cut(s) | 604 |
| PspN4I | GGNNCC | 2 cut(s) | 109, 730 |
| PspPI | GGNCC | 4 cut(s) | 205, 729, 860, 1331 |
| PsuI | RGATCY | 1 cut(s) | 676 |
| PvuII | CAGCTG | 1 cut(s) | 83 |
| RsaI | GTAC | 4 cut(s) | 73, 334, 477, 1376 |
| RsaNI | GTAC | 4 cut(s) | 72, 333, 476, 1375 |
| RseI | CAYNNNNRTG | 2 cut(s) | 402, 1208 |
| SaqAI | TTAA | 5 cut(s) | 599, 762, 1152, 1337, 1389 |
| SatI | GCNGC | 7 cut(s) | 81, 84, 137, 518, 1116, 1353, 1356 |
| Sau3AI | GATC | 5 cut(s) | 12, 124, 415, 676, 1420 |
| Sau96I | GGNCC | 4 cut(s) | 205, 729, 860, 1331 |
| SchI | GAGTC | 1 cut(s) | 285 |
| ScrFI | CCNGG | 1 cut(s) | 606 |
| SduI | GDGCHC | 2 cut(s) | 112, 1372 |
| SinI | GGWCC | 3 cut(s) | 729, 860, 1331 |
| SmiMI | CAYNNNNRTG | 2 cut(s) | 402, 1208 |
| SphI | GCATGC | 2 cut(s) | 544, 1073 |
| Sse9I | AATT | 5 cut(s) | 749, 864, 889, 1104, 1234 |
| SsiI | CCGC | 1 cut(s) | 1013 |
| SspMI | CTAG | 4 cut(s) | 209, 225, 468, 1295 |
| StyD4I | CCNGG | 1 cut(s) | 604 |
| StyI | CCWWGG | 1 cut(s) | 219 |
| TaaI | ACNGT | 7 cut(s) | 165, 337, 524, 808, 938, 1126, 1374 |
| TaiI | ACGT | 1 cut(s) | 742 |
| TaqI | TCGA | 3 cut(s) | 400, 829, 951 |
| TasI | AATT | 5 cut(s) | 749, 864, 889, 1104, 1234 |
| TatI | WGTACW | 4 cut(s) | 71, 332, 475, 1374 |
| TfiI | GAWTC | 3 cut(s) | 649, 916, 1188 |
| Tru1I | TTAA | 5 cut(s) | 599, 762, 1152, 1337, 1389 |
| Tru9I | TTAA | 5 cut(s) | 599, 762, 1152, 1337, 1389 |
| TscAI | CASTG | 2 cut(s) | 1129, 1215 |
| TseFI | GTSAC | 1 cut(s) | 735 |
| TseI | GCWGC | 7 cut(s) | 80, 83, 136, 517, 1115, 1352, 1355 |
| Tsp45I | GTSAC | 1 cut(s) | 735 |
| TspDTI | ATGAA | 6 cut(s) | 17, 641, 929, 1011, 1040, 1266 |
| TspGWI | ACGGA | 1 cut(s) | 1380 |
| TspRI | CASTG | 2 cut(s) | 1129, 1215 |
| VpaK11BI | GGWCC | 3 cut(s) | 729, 860, 1331 |
| XceI | RCATGY | 4 cut(s) | 407, 544, 1073, 1097 |
| XmnI | GAANNNNTTC | 1 cut(s) | 1192 |
| XspI | CTAG | 4 cut(s) | 209, 225, 468, 1295 |
| Zsp2I | ATGCAT | 6 cut(s) | 40, 409, 542, 1071, 1174, 1414 |