pycom12g21810

DNA-damage-repair toleration protein

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
pyrus_communis
Chr12
OG0014381
Physical Location & Seq
Forward (+)
22909319 .. 22910251
933 bp
Loading structure...
UTR
Exon/CDS
Intron
pycom12g21810.1

Sequence Viewer

Length: 933 bp
ATGGCCGAAGAAGCTCCCAGCAAACGCCCACTGAAAATCATAGCCGGCGCCGACTCCTTCGGCTGCTCTCTTAAGGACGCCTTGGTGTCCCACCTCCGCTCCCTCAACATCGACGTTGAAGACCTCGGCACCTCCTCCTACTACTCCATCGCCGCTGACGTCGGCAGCCGCGTCTCCTCCTCCACCTCCAATTCCGAGGAGATCCGGGGCCTCGTCGCCTGTGGTACCGGCGTCGGAGTCTCAATCTTCGCCAACAAGTTCCCCGGCGTATTCGCCGCCACGTGCCTCACTCCCTCCGACGCCCAGAACGCCCGATCCATCAACAACTCCAACGTCCTCGCCGTCTCCGGCATGTCCACGTCACCCGACTCCGCCATCGAGATCCTCGACACCTGGCTCAACACCCCCTTCAAATCCCCCTGCCCCGCTTCCGATTCCAAACCCTGGCCGCCCGAACTCGAGTCCTTCCTCGACAATTCAATCCAAGAAATGCCCAAAATTGGAGGGGCTAATAAAATTGTAGATTCCGAGGAGGCTTCTTGCGCAATCTGCTGTTTGGTGAAGAACAGGGAATTGAACCCGATCGACATTATTCCCGGCGGGTCGATGAAGATTCTGAGGGAGACGCCGACGTCGGCGATTGTTAGGTTTAAGGCCGGGAGCGTGGAGCCGGCGCACCACCACACGTTCGGGCACGATCTGGTGGTGCTGTGGGGGAAAAAGAGCGTGTGGAATTTGACTAAAGAGAAAAGGTTCGATCTGACCGGCGGTGATTACTTGTTTACTCCGGCGGGGGATGTGCACAGAGTCAAGTACTATGAAGATACTGAGTTTTTGATCACCTGGGATGGCCATTGGGACATGTTTTTTGATGAGGATCTTGAGGCTGCAAAGAAGGCTGTTCAGCAGGAATTGGAGAAGGGGTCCGAGTGA

Protein Analysis

311

Amino Acids

33.63

Weight (kDa)

4.98

Isoelectric Point (pI)

48.69

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
LacAB_rpiB PF02502 13 - 138 9.8e-31 Ribose/Galactose Isomerase
Cupin_7 PF12973 196 - 285 4.4e-07 ChrR Cupin-like domain
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
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Publication-ready
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Orthologous Genes (Group: OG0014381)

Species Orthologous Gene IDs
arabidopsis_thaliana AT3G04880
fragaria_vesca FvH4_6g03430
malus_domestica MD12G1237200.v1.1
prunus_persica Prupe.6G339900_v2.0.a1
pyrus_communis pycom12g21810
rosa_chinensis RchiOBHm_Chr3g0451931
rosa_laevigata RLG00000025637
rosa_multiflora Rmu_sc0002901.1_g000002 Rmu_ssc0000467.1_g000022
rosa_roxburghii Rroxscaffold_164G00436200 Rroxscaffold_6G00429100
rosa_rugosa Rorug02G0637500
rosa_samantha Rh3AG039200 Rh3BG040500 Rh3CG039000 Rh3DG039700
rosa_wichuraiana Rw3G002930

Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AasI GACNNNNNNGTC 1 cut(s) 631
AatII GACGTC 2 cut(s) 162, 635
Acc16I TGCGCA 1 cut(s) 544
Acc65I GGTACC 1 cut(s) 224
AccB1I GGYRCC 3 cut(s) 47, 128, 224
AccB7I CCANNNNNTGG 1 cut(s) 444
AccBSI CCGCTC 1 cut(s) 99
AccII CGCG 1 cut(s) 171
AclWI GGATC 4 cut(s) 196, 309, 376, 885
AcoI YGGCCR 3 cut(s) 3, 446, 850
AcsI RAATTY 1 cut(s) 733
AcvI CACGTG 1 cut(s) 282
AcyI GRCGYC 7 cut(s) 48, 78, 159, 231, 300, 626, 632
AfaI GTAC 2 cut(s) 226, 815
AfiI CCNNNNNNNGG 2 cut(s) 444, 500
AflII CTTAAG 1 cut(s) 71
AflIII ACRYGT 2 cut(s) 684, 861
AgsI TTSAA 4 cut(s) 119, 412, 480, 577
AjiI CACGTC 1 cut(s) 360
AjnI CCWGG 3 cut(s) 392, 443, 842
AloI GAACNNNNNNTCC 2 cut(s) 299, 331
AluBI AGCT 1 cut(s) 14
AluI AGCT 1 cut(s) 14
Alw21I GWGCWC 1 cut(s) 804
Alw26I GTCTC 4 cut(s) 178, 244, 349, 617
Alw44I GTGCAC 1 cut(s) 800
AlwI GGATC 4 cut(s) 196, 309, 376, 885
Ama87I CYCGRG 1 cut(s) 458
AoxI GGCC 5 cut(s) 3, 208, 446, 654, 850
ApaLI GTGCAC 1 cut(s) 800
ApeKI GCWGC 3 cut(s) 63, 165, 887
ApoI RAATTY 1 cut(s) 733
ArsI GACNNNNNNTTYG 2 cut(s) 851, 883
Asp700I GAANNNNTTC 1 cut(s) 752
Asp718I GGTACC 1 cut(s) 224
AspLEI GCGC 3 cut(s) 50, 545, 676
AspS9I GGNCC 2 cut(s) 208, 924
AsuC2I CCSGG 4 cut(s) 206, 264, 597, 658
AsuHPI GGTGA 4 cut(s) 354, 571, 782, 832
AvaI CYCGRG 1 cut(s) 458
AvaII GGWCC 1 cut(s) 924
BaeGI GKGCMC 2 cut(s) 696, 804
BaeI ACNNNNGTAYC 2 cut(s) 216, 249
BalI TGGCCA 1 cut(s) 852
BanI GGYRCC 3 cut(s) 47, 128, 224
BbrPI CACGTG 1 cut(s) 282
BbsI GAAGAC 1 cut(s) 126
Bbv12I GWGCWC 1 cut(s) 804
BbvI GCAGC 3 cut(s) 50, 177, 874
BccI CCATC 4 cut(s) 155, 326, 383, 842
BceAI ACGGC 1 cut(s) 326
BciT130I CCWGG 3 cut(s) 394, 445, 844
BclI TGATCA 1 cut(s) 837
BcnI CCSGG 4 cut(s) 206, 264, 597, 658
BcoDI GTCTC 4 cut(s) 178, 244, 349, 617
BfoI RGCGCY 1 cut(s) 51
BfrI CTTAAG 1 cut(s) 71
BisI GCNGC 7 cut(s) 64, 153, 166, 169, 276, 449, 888
BlsI GCNGC 7 cut(s) 65, 154, 167, 170, 277, 450, 889
BmcAI AGTACT 1 cut(s) 815
Bme1390I CCNGG 7 cut(s) 206, 264, 394, 445, 597, 658, 844
Bme18I GGWCC 1 cut(s) 924
BmeT110I CYCGRG 1 cut(s) 458
BmgBI CACGTC 1 cut(s) 360
BmgT120I GGNCC 2 cut(s) 208, 924
BmiI GGNNCC 6 cut(s) 49, 130, 209, 226, 669, 925
BmrFI CCNGG 7 cut(s) 206, 264, 394, 445, 597, 658, 844
BpiI GAAGAC 1 cut(s) 126
BpuEI CTTGAG 1 cut(s) 902
BpuMI CCSGG 4 cut(s) 206, 264, 597, 658
BsaAI YACGTR 1 cut(s) 282
BsaBI GATNNNNATC 1 cut(s) 876
BsaHI GRCGYC 7 cut(s) 48, 78, 159, 231, 300, 626, 632
BsaJI CCNNGG 8 cut(s) 81, 124, 195, 205, 262, 443, 528, 843
BsaXI ACNNNNNCTCC 3 cut(s) 83, 113, 908
Bsc4I CCNNNNNNNGG 2 cut(s) 444, 500
Bse118I RCCGGY 4 cut(s) 44, 227, 670, 764
Bse8I GATNNNNATC 1 cut(s) 876
BseBI CCWGG 3 cut(s) 394, 445, 844
BseDI CCNNGG 8 cut(s) 81, 124, 195, 205, 262, 443, 528, 843
BseGI GGATG 2 cut(s) 802, 853
BseJI GATNNNNATC 1 cut(s) 876
BseLI CCNNNNNNNGG 2 cut(s) 444, 500
BseMII CTCAG 2 cut(s) 608, 819
BseRI GAGGAG 5 cut(s) 124, 166, 169, 212, 545
BseSI GKGCMC 2 cut(s) 696, 804
BseXI GCAGC 3 cut(s) 50, 177, 874
BseYI CCCAGC 1 cut(s) 17
Bsh1236I CGCG 1 cut(s) 171
Bsh1285I CGRYCG 1 cut(s) 585
BshFI GGCC 5 cut(s) 5, 210, 448, 656, 852
BshNI GGYRCC 3 cut(s) 47, 128, 224
BsiEI CGRYCG 1 cut(s) 585
BsiHKAI GWGCWC 1 cut(s) 804
BsiHKCI CYCGRG 1 cut(s) 458
BslFI GGGAC 2 cut(s) 73, 872
BslI CCNNNNNNNGG 2 cut(s) 444, 500
BsmAI GTCTC 4 cut(s) 178, 244, 349, 617
BsmBI CGTCTC 3 cut(s) 178, 349, 617
BsmFI GGGAC 2 cut(s) 73, 872
BsnI GGCC 5 cut(s) 5, 210, 448, 656, 852
BsoBI CYCGRG 1 cut(s) 458
Bsp1286I GDGCHC 2 cut(s) 696, 804
Bsp143I GATC 8 cut(s) 201, 314, 381, 582, 697, 757, 837, 877
BspANI GGCC 5 cut(s) 5, 210, 448, 656, 852
BspCNI CTCAG 2 cut(s) 609, 820
BspFNI CGCG 1 cut(s) 171
BspLI GGNNCC 6 cut(s) 49, 130, 209, 226, 669, 925
BspPI GGATC 4 cut(s) 196, 309, 376, 885
BspT107I GGYRCC 3 cut(s) 47, 128, 224
BspTI CTTAAG 1 cut(s) 71
BsrBI CCGCTC 1 cut(s) 99
BsrFI RCCGGY 4 cut(s) 44, 227, 670, 764
BssAI RCCGGY 4 cut(s) 44, 227, 670, 764
BssECI CCNNGG 8 cut(s) 81, 124, 195, 205, 262, 443, 528, 843
BssMI GATC 8 cut(s) 201, 314, 381, 582, 697, 757, 837, 877
BssNI GRCGYC 7 cut(s) 48, 78, 159, 231, 300, 626, 632
BssT1I CCWWGG 1 cut(s) 81
Bst2UI CCWGG 3 cut(s) 394, 445, 844
BstACI GRCGYC 7 cut(s) 48, 78, 159, 231, 300, 626, 632
BstAFI CTTAAG 1 cut(s) 71
BstBAI YACGTR 1 cut(s) 282
BstC8I GCNNGC 2 cut(s) 46, 672
BstDEI CTNAG 2 cut(s) 617, 828
BstF5I GGATG 2 cut(s) 802, 853
BstFNI CGCG 1 cut(s) 171
BstH2I RGCGCY 1 cut(s) 51
BstHHI GCGC 3 cut(s) 50, 545, 676
BstKTI GATC 8 cut(s) 204, 317, 384, 585, 700, 760, 840, 880
BstMAI GTCTC 4 cut(s) 178, 244, 349, 617
BstMBI GATC 8 cut(s) 201, 314, 381, 582, 697, 757, 837, 877
BstMCI CGRYCG 1 cut(s) 585
BstMWI GCNNNNNNNGC 5 cut(s) 11, 308, 542, 549, 896
BstNI CCWGG 3 cut(s) 394, 445, 844
BstNSI RCATGY 2 cut(s) 355, 865
BstSCI CCNGG 7 cut(s) 204, 262, 392, 443, 595, 656, 842
BstSLI GKGCMC 2 cut(s) 696, 804
BstUI CGCG 1 cut(s) 171
BstV1I GCAGC 3 cut(s) 50, 177, 874
BstV2I GAAGAC 1 cut(s) 126
BstX2I RGATCY 3 cut(s) 201, 381, 877
BstYI RGATCY 3 cut(s) 201, 381, 877
BsuRI GGCC 5 cut(s) 5, 210, 448, 656, 852
BtgZI GCGATG 1 cut(s) 133
BtrI CACGTC 1 cut(s) 360
BtsCI GGATG 2 cut(s) 802, 853
BtsIMutI CAGTG 1 cut(s) 29
Cac8I GCNNGC 2 cut(s) 46, 672
CfoI GCGC 3 cut(s) 50, 545, 676
Cfr10I RCCGGY 4 cut(s) 44, 227, 670, 764
Cfr13I GGNCC 2 cut(s) 208, 924
CseI GACGC 5 cut(s) 86, 160, 220, 308, 634
Csp6I GTAC 2 cut(s) 225, 814
CviAII CATG 2 cut(s) 352, 862
CviQI GTAC 2 cut(s) 225, 814
DdeI CTNAG 2 cut(s) 617, 828
DinI GGCGCC 1 cut(s) 49
DpnI GATC 8 cut(s) 203, 316, 383, 584, 699, 759, 839, 879
DpnII GATC 8 cut(s) 201, 314, 381, 582, 697, 757, 837, 877
DrdI GACNNNNNNGTC 1 cut(s) 631
DseDI GACNNNNNNGTC 1 cut(s) 631
EaeI YGGCCR 3 cut(s) 3, 446, 850
EciI GGCGGA 1 cut(s) 361
Eco130I CCWWGG 1 cut(s) 81
Eco47I GGWCC 1 cut(s) 924
Eco72I CACGTG 1 cut(s) 282
Eco88I CYCGRG 1 cut(s) 458
EcoO109I RGGNCCY 1 cut(s) 208
EcoRII CCWGG 3 cut(s) 392, 443, 842
EcoT14I CCWWGG 1 cut(s) 81
EgeI GGCGCC 1 cut(s) 49
EheI GGCGCC 1 cut(s) 49
ErhI CCWWGG 1 cut(s) 81
Esp3I CGTCTC 3 cut(s) 178, 349, 617
FaeI CATG 2 cut(s) 355, 865
FaiI YATR 4 cut(s) 41, 353, 819, 863
FalI AAGNNNNNCTT 2 cut(s) 65, 97
FaqI GGGAC 2 cut(s) 73, 872
FatI CATG 2 cut(s) 351, 861
FauI CCCGC 3 cut(s) 433, 593, 784
FbaI TGATCA 1 cut(s) 837
Fnu4HI GCNGC 7 cut(s) 64, 153, 166, 169, 276, 449, 888
FokI GGATG 2 cut(s) 809, 860
Fsp4HI GCNGC 7 cut(s) 64, 153, 166, 169, 276, 449, 888
FspI TGCGCA 1 cut(s) 544
GlaI GCGC 3 cut(s) 49, 544, 675
GluI GCNGC 7 cut(s) 64, 153, 166, 169, 276, 449, 888
GsaI CCCAGC 1 cut(s) 21
HaeII RGCGCY 1 cut(s) 51
HaeIII GGCC 5 cut(s) 5, 210, 448, 656, 852
HgaI GACGC 5 cut(s) 86, 160, 220, 308, 634
HhaI GCGC 3 cut(s) 50, 545, 676
Hin1I GRCGYC 7 cut(s) 48, 78, 159, 231, 300, 626, 632
Hin1II CATG 2 cut(s) 355, 865
Hin6I GCGC 3 cut(s) 48, 543, 674
HinP1I GCGC 3 cut(s) 48, 543, 674
HinfI GANTC 8 cut(s) 53, 237, 368, 434, 461, 524, 613, 807
HphI GGTGA 4 cut(s) 354, 571, 782, 832
Hpy166II GTNNAC 3 cut(s) 357, 783, 802
Hpy188I TCNGA 8 cut(s) 196, 236, 298, 433, 529, 618, 762, 928
Hpy188III TCNNGA 2 cut(s) 379, 881
Hpy8I GTNNAC 3 cut(s) 357, 783, 802
Hpy99I CGWCG 7 cut(s) 116, 164, 218, 236, 302, 634, 637
HpyAV CCTTC 5 cut(s) 67, 418, 475, 889, 913
HpyCH4IV ACGT 7 cut(s) 114, 159, 281, 333, 359, 632, 686
HpyCH4V TGCA 2 cut(s) 802, 890
HpyF10VI GCNNNNNNNGC 5 cut(s) 11, 308, 542, 549, 896
HpyF3I CTNAG 2 cut(s) 617, 828
HpySE526I ACGT 7 cut(s) 114, 159, 281, 333, 359, 632, 686
Hsp92I GRCGYC 7 cut(s) 48, 78, 159, 231, 300, 626, 632
Hsp92II CATG 2 cut(s) 355, 865
HspAI GCGC 3 cut(s) 48, 543, 674
KasI GGCGCC 1 cut(s) 47
KpnI GGTACC 1 cut(s) 228
KroI GCCGGC 2 cut(s) 44, 670
KroNI GCCGGC 2 cut(s) 46, 672
Ksp22I TGATCA 1 cut(s) 837
Kzo9I GATC 8 cut(s) 201, 314, 381, 582, 697, 757, 837, 877
LmnI GCTCC 4 cut(s) 19, 104, 660, 667
Lsp1109I GCAGC 3 cut(s) 50, 177, 874
MaeII ACGT 7 cut(s) 114, 159, 281, 333, 359, 632, 686
MaeIII GTNAC 1 cut(s) 360
MalI GATC 8 cut(s) 203, 316, 383, 584, 699, 759, 839, 879
MbiI CCGCTC 1 cut(s) 99
MboI GATC 8 cut(s) 201, 314, 381, 582, 697, 757, 837, 877
MboII GAAGA 6 cut(s) 20, 131, 238, 574, 622, 833
MflI RGATCY 3 cut(s) 201, 381, 877
MhlI GDGCHC 2 cut(s) 696, 804
MlsI TGGCCA 1 cut(s) 852
MluCI AATT 7 cut(s) 190, 475, 498, 516, 572, 733, 911
MluNI TGGCCA 1 cut(s) 852
Mly113I GGCGCC 1 cut(s) 48
MlyI GAGTC 5 cut(s) 47, 246, 362, 470, 816
MmeI TCCRAC 3 cut(s) 214, 321, 354
Mox20I TGGCCA 1 cut(s) 852
MroNI GCCGGC 2 cut(s) 44, 670
MroXI GAANNNNTTC 1 cut(s) 752
MscI TGGCCA 1 cut(s) 852
MseI TTAA 2 cut(s) 72, 651
Msp20I TGGCCA 1 cut(s) 852
MspA1I CMGCKG 1 cut(s) 155
MspCI CTTAAG 1 cut(s) 71
MspR9I CCNGG 7 cut(s) 206, 264, 394, 445, 597, 658, 844
MvaI CCWGG 3 cut(s) 394, 445, 844
MvnI CGCG 1 cut(s) 171
MwoI GCNNNNNNNGC 5 cut(s) 11, 308, 542, 549, 896
NaeI GCCGGC 2 cut(s) 46, 672
NarI GGCGCC 1 cut(s) 48
NciI CCSGG 4 cut(s) 206, 264, 597, 658
NdeII GATC 8 cut(s) 201, 314, 381, 582, 697, 757, 837, 877
NgoMIV GCCGGC 2 cut(s) 44, 670
NlaIII CATG 2 cut(s) 355, 865
NlaIV GGNNCC 6 cut(s) 49, 130, 209, 226, 669, 925
NmeAIII GCCGAG 1 cut(s) 105
NmuCI GTSAC 1 cut(s) 360
NsbI TGCGCA 1 cut(s) 544
NspI RCATGY 2 cut(s) 355, 865
PaeR7I CTCGAG 1 cut(s) 458
PciI ACATGT 1 cut(s) 861
PcsI WCGNNNNNNNCGW 4 cut(s) 156, 168, 339, 384
PdiI GCCGGC 2 cut(s) 46, 672
PdmI GAANNNNTTC 1 cut(s) 752
PfeI GAWTC 3 cut(s) 434, 524, 613
PflMI CCANNNNNTGG 1 cut(s) 444
PkrI GCNGC 7 cut(s) 65, 154, 167, 170, 277, 450, 889
Ple19I CGATCG 1 cut(s) 585
PleI GAGTC 5 cut(s) 47, 245, 362, 469, 815
PluTI GGCGCC 1 cut(s) 51
PmaCI CACGTG 1 cut(s) 282
PmlI CACGTG 1 cut(s) 282
PpsI GAGTC 5 cut(s) 47, 245, 362, 469, 815
Ppu21I YACGTR 1 cut(s) 282
PscI ACATGT 1 cut(s) 861
Psp6I CCWGG 3 cut(s) 392, 443, 842
PspCI CACGTG 1 cut(s) 282
PspFI CCCAGC 1 cut(s) 17
PspGI CCWGG 3 cut(s) 392, 443, 842
PspN4I GGNNCC 6 cut(s) 49, 130, 209, 226, 669, 925
PspPI GGNCC 2 cut(s) 208, 924
PspXI VCTCGAGB 1 cut(s) 458
PsuI RGATCY 3 cut(s) 201, 381, 877
PvuI CGATCG 1 cut(s) 585
RsaI GTAC 2 cut(s) 226, 815
RsaNI GTAC 2 cut(s) 225, 814
SaqAI TTAA 2 cut(s) 72, 651
SatI GCNGC 7 cut(s) 64, 153, 166, 169, 276, 449, 888
Sau3AI GATC 8 cut(s) 201, 314, 381, 582, 697, 757, 837, 877
Sau96I GGNCC 2 cut(s) 208, 924
ScaI AGTACT 1 cut(s) 815
SchI GAGTC 5 cut(s) 47, 246, 362, 470, 816
ScrFI CCNGG 7 cut(s) 206, 264, 394, 445, 597, 658, 844
SduI GDGCHC 2 cut(s) 696, 804
SfoI GGCGCC 1 cut(s) 49
Sfr274I CTCGAG 1 cut(s) 458
SinI GGWCC 1 cut(s) 924
SlaI CTCGAG 1 cut(s) 458
SmlI CTYRAG 3 cut(s) 71, 458, 881
SmoI CTYRAG 3 cut(s) 71, 458, 881
Sse9I AATT 7 cut(s) 190, 475, 498, 516, 572, 733, 911
SspDI GGCGCC 1 cut(s) 47
StyD4I CCNGG 7 cut(s) 204, 262, 392, 443, 595, 656, 842
StyI CCWWGG 1 cut(s) 81
TaiI ACGT 7 cut(s) 117, 162, 284, 336, 362, 635, 689
TaqI TCGA 8 cut(s) 111, 378, 387, 459, 471, 585, 605, 756
TasI AATT 7 cut(s) 190, 475, 498, 516, 572, 733, 911
TatI WGTACW 1 cut(s) 813
TauI GCSGC 4 cut(s) 155, 171, 278, 451
TfiI GAWTC 3 cut(s) 434, 524, 613
Tru1I TTAA 2 cut(s) 72, 651
Tru9I TTAA 2 cut(s) 72, 651
TscAI CASTG 1 cut(s) 36
TseFI GTSAC 1 cut(s) 360
TseI GCWGC 3 cut(s) 63, 165, 887
Tsp45I GTSAC 1 cut(s) 360
TspDTI ATGAA 2 cut(s) 623, 834
TspRI CASTG 1 cut(s) 36
Van91I CCANNNNNTGG 1 cut(s) 444
Vha464I CTTAAG 1 cut(s) 71
VneI GTGCAC 1 cut(s) 800
VpaK11BI GGWCC 1 cut(s) 924
XapI RAATTY 1 cut(s) 733
XceI RCATGY 2 cut(s) 355, 865
XhoI CTCGAG 1 cut(s) 458
XmnI GAANNNNTTC 1 cut(s) 752
ZraI GACGTC 2 cut(s) 160, 633
ZrmI AGTACT 1 cut(s) 815
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.