Basic Information

Type: gene

Biological Identity

Species

malus_domestica

Chromosome

Chr07

Orthogroup ID

OG0005836

Physical Location & Seq

Genomic Coordinates Reverse (-)

20161714 .. 20164439

Gene Structure 2726 bp

Loading structure...

UTR

Exon/CDS

Intron

Transcript / Protein ID

MD07G1139000.v1.1.491

Sequence Viewer

CDS Protein Promoter (2k)

Length: 1302 bp

ATGCTCCTTCCTTCTTCCCTCTCCCTCCAAACCCTAGCTCCTCCAAATGCTGACACAATCCAGAAACCCCATCAAACTCTCCCCCAAAATCTCACTCTCTTCCAACTTGTCCACCCCCAACACTTTCCCACATTACAATTTCCAAACCTTCCCTCCGGACCAAAAACCCTCAAGTTCAAGCTCCTCTGCTCACAATCCCCAAACCCAAACCCTTCACCGCCATCATCTTCCTCTCCGGTCCAAACCCTAATCTCAATACTGCGAATCATACCCGACTGGTCAGACCGCACGCAAGAGCGTGGAATGAGACAGCACAGAACACTTTATGACCATGAGAAATGGATGCATCACAGAAGCTCCTACCGCCATCTCCGGCACTTGCTCTCAAGCCTTTCGTCAAGAGTCATCTTGTCTTTGATACCGCCGGTGATTGCTTTTACTTTGGTAGCTGTGGTGATTGCTAGCTATAATACAGCAGTTGCGTTGGATTTGCTTCCGGGAATTTTCCCGTTGTTGAGGTCCTCATCTTTGCCATACCAGCTCACAGCGCCGGCATTGGCGCTGTTGCTGGTGTTCAGGACAGAGGCTTCGTATTCGAGGTTTGAAGAAGGGAGGAAGGCTTGGACTGAGGTGATTGCAGGGGCTAATGATTTCGCGAGGCAGATCATTTCTAGTGTTGAGACTTCGGGTGATGCACAGCTCAAGAAGGCACTTTTGCAGTATATTGTGGCCTTCCCTGTTGCGCTGAAGTGTCATGTCATTTATGGCTCAGATATTGCACGAGACCTCCAAAATTTGCTTGAAGTTGATGATCTGCTAGTAGTTTTGAACTCAAAACATCGACCCGGCTGCATTATTCAGTTCATCTCCCGGAGCCTCCAATTGCTAAAGTTGGAGGAATCGAGGAGAATTATGTTGCAATCAAAGATCTCTTGTTTCCATGAAGGAATTGGCATATGTGAACAGCTAATTGGTACTCCCATCCCTCTGTCTTATACGCGCTTGACCTCAAGGTTTCTAGTCCTCTGGCATCTCACTCTACCTATTATCCTATGGGATGATTGCCACTGGATTGTGGTTCCCGCTACTTTCATCAGTGCAGCTTCACTGTTCTGTATCGAACAAGTGGGTGTTCTGATTGAGGAGCCATTTCCCATGCTTGCCCTTGACGACCTTTGCAACTCAGTTCGAAACAACGTACAGGAGGCCCTTGCAAGCGAAAAATTAATCCGCGCACGGCTTGCTGCAAAAGGAAGGATCCAGTCTGAGCAGCAGTTTCAAAATGGGCAGCCTAGGCCTTAA

Functional Annotation

Gene Ontology

Molecular Function
Biological Process
Cellular Component

GO:0003674 GO:0005215 GO:0005216 GO:0005244 GO:0005247 GO:0005253 GO:0005254 GO:0005575 GO:0005622 GO:0005623 GO:0005737 GO:0006091 GO:0006810 GO:0006811 GO:0006820 GO:0006821 GO:0006996 GO:0008150 GO:0008152 GO:0008308 GO:0008509 GO:0009507 GO:0009532 GO:0009533 GO:0009534 GO:0009536 GO:0009570 GO:0009579 GO:0009657 GO:0009668 GO:0009987 GO:0010027 GO:0010109 GO:0015075 GO:0015103 GO:0015108 GO:0015267 GO:0015318 GO:0015698 GO:0015979 GO:0016020 GO:0016043 GO:0019222 GO:0019684 GO:0022803 GO:0022832 GO:0022836 GO:0022838 GO:0022839 GO:0022857 GO:0031323 GO:0031976 GO:0031984 GO:0034220 GO:0034357 GO:0042548 GO:0042651 GO:0043226 GO:0043227 GO:0043229 GO:0043231 GO:0043467 GO:0044237 GO:0044422 GO:0044424 GO:0044434 GO:0044435 GO:0044436 GO:0044444 GO:0044446 GO:0044464 GO:0050789 GO:0050794 GO:0051179 GO:0051234 GO:0055085 GO:0061024 GO:0065007 GO:0071840 GO:0098656 GO:0098660 GO:0098661 GO:1902476

KEGG Pathways

Metabolic & Signaling

No pathways identified.

Pfam Domains

Protein Families

Bestrophin

Protein Analysis

434

Amino Acids

48.61

Weight (kDa)

9.0

Isoelectric Point (pI)

57.85

Instability Index

Protein Domains (Pfam)

Domain Name	Pfam ID	Position	E-value	Description
Bestrophin_2	PF25539	114 - 402	1.3e-85	Bacterial/Fungal Bestrophin protein

Hydrophobicity Profile (Kyte-Doolittle)

AI Structure Prediction Report

Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter

Style Settings

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Align Labels (Cladogram)

Image

Tree File

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Publication-ready

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Orthologous Genes (Group: OG0005836)

Species	Orthologous Gene IDs
arabidopsis_thaliana	AT2G45870 AT2G45870 AT2G45870 AT3G61320 AT3G61320 AT3G61320 AT3G61320
fragaria_vesca	FvH4_7g14170
malus_domestica	MD01G1057600.v1.1 MD01G1202300.v1.1 MD07G1139000.v1.1
prunus_persica	Prupe.2G168100_v2.0.a1 Prupe.2G168100_v2.0.a1 Prupe.2G168100_v2.0.a1
pyrus_communis	pycom01g08760 pycom07g13600
rosa_chinensis	RchiOBHm_Chr1g0355071
rosa_laevigata	RLG00000028179
rosa_multiflora	Rmu_sc0003115.1_g000030
rosa_roxburghii	Rroxscaffold_4G00300690
rosa_rugosa	Rorug01G0244900
rosa_samantha	Rh1AG257200 Rh1BG226500 Rh1CG240800 Rh1DG254100 Rh4DG156900
rosa_wichuraiana	Rw0G011210 Rw1G022680

Restriction Enzyme Sites

1 / 10

Enzyme	Recognition Site	Cut Count	Positions (bp)
AccII	CGCG	3 cut(s)	656, 1000, 1233
AccIII	TCCGGA	1 cut(s)	155
AciI	CCGC	6 cut(s)	218, 286, 364, 422, 1083, 1231
AclWI	GGATC	2 cut(s)	1252, 1265
AcsI	RAATTY	2 cut(s)	501, 793
AcuI	CTGAAG	1 cut(s)	767
AfaI	GTAC	2 cut(s)	976, 1200
AgsI	TTSAA	5 cut(s)	178, 605, 803, 829, 1280
AjuI	GAANNNNNNNTTGG	2 cut(s)	954, 986
AluBI	AGCT	9 cut(s)	38, 181, 357, 449, 465, 541, 700, 967, 1103
AluI	AGCT	9 cut(s)	38, 181, 357, 449, 465, 541, 700, 967, 1103
Alw26I	GTCTC	3 cut(s)	301, 674, 777
AlwI	GGATC	2 cut(s)	1252, 1265
Aor13HI	TCCGGA	1 cut(s)	155
AoxI	GGCC	3 cut(s)	729, 1206, 1295
ApeKI	GCWGC	5 cut(s)	849, 1100, 1244, 1270, 1288
ApoI	RAATTY	2 cut(s)	501, 793
ArsI	GACNNNNNNTTYG	2 cut(s)	571, 603
AseI	ATTAAT	1 cut(s)	1226
AspA2I	CCTAGG	1 cut(s)	1292
AspLEI	GCGC	5 cut(s)	550, 562, 745, 1002, 1235
AspS9I	GGNCC	4 cut(s)	158, 238, 519, 1207
AsuC2I	CCSGG	3 cut(s)	498, 846, 871
AsuHPI	GGTGA	5 cut(s)	207, 439, 466, 643, 701
AsuII	TTCGAA	1 cut(s)	1189
AsuNHI	GCTAGC	1 cut(s)	461
AvaII	GGWCC	3 cut(s)	158, 238, 519
AvrII	CCTAGG	1 cut(s)	1292
BamHI	GGATCC	1 cut(s)	1257
BauI	CACGAG	1 cut(s)	780
BbvI	GCAGC	4 cut(s)	836, 1112, 1231, 1282
BccI	CCATC	4 cut(s)	78, 229, 375, 989
BceAI	ACGGC	1 cut(s)	1253
BcgI	CGANNNNNNTGC	2 cut(s)	831, 865
BcnI	CCSGG	3 cut(s)	498, 846, 871
BcoDI	GTCTC	3 cut(s)	301, 674, 777
BfaI	CTAG	6 cut(s)	35, 462, 672, 818, 1019, 1293
BfoI	RGCGCY	2 cut(s)	551, 563
BglII	AGATCT	1 cut(s)	927
BisI	GCNGC	5 cut(s)	850, 1101, 1245, 1271, 1289
BlnI	CCTAGG	1 cut(s)	1292
BlsI	GCNGC	5 cut(s)	851, 1102, 1246, 1272, 1290
Bme1390I	CCNGG	3 cut(s)	498, 846, 871
Bme18I	GGWCC	3 cut(s)	158, 238, 519
BmgT120I	GGNCC	4 cut(s)	158, 238, 519, 1207
BmiI	GGNNCC	4 cut(s)	875, 1080, 1146, 1259
BmrFI	CCNGG	3 cut(s)	498, 846, 871
BmsI	GCATC	4 cut(s)	333, 355, 682, 1039
BmtI	GCTAGC	1 cut(s)	465
Bpu14I	TTCGAA	1 cut(s)	1189
BpuEI	CTTGAG	4 cut(s)	155, 370, 686, 994
BpuMI	CCSGG	3 cut(s)	498, 846, 871
BsaI	GGTCTC	1 cut(s)	777
BsaJI	CCNNGG	1 cut(s)	1292
BsaWI	WCCGGW	2 cut(s)	155, 235
BsaXI	ACNNNNNCTCC	8 cut(s)	22, 52, 137, 167, 341, 371, 771, 801
Bse118I	RCCGGY	2 cut(s)	424, 550
Bse1I	ACTGG	3 cut(s)	281, 1073, 1261
BseAI	TCCGGA	1 cut(s)	155
BseDI	CCNNGG	1 cut(s)	1292
BseGI	GGATG	3 cut(s)	348, 981, 1063
BseMII	CTCAG	4 cut(s)	618, 783, 1197, 1257
BseNI	ACTGG	3 cut(s)	281, 1073, 1261
BseRI	GAGGAG	4 cut(s)	30, 173, 919, 1157
BseXI	GCAGC	4 cut(s)	836, 1112, 1231, 1282
BsgI	GTGCAG	1 cut(s)	1119
Bsh1236I	CGCG	3 cut(s)	656, 1000, 1233
BshFI	GGCC	3 cut(s)	731, 1208, 1297
BsiSI	CCGG	8 cut(s)	156, 236, 373, 425, 497, 551, 846, 871
BsmAI	GTCTC	3 cut(s)	301, 674, 777
BsnI	GGCC	3 cut(s)	731, 1208, 1297
Bso31I	GGTCTC	1 cut(s)	777
Bsp119I	TTCGAA	1 cut(s)	1189
Bsp13I	TCCGGA	1 cut(s)	155
Bsp143I	GATC	4 cut(s)	663, 811, 927, 1257
Bsp68I	TCGCGA	1 cut(s)	656
BspACI	CCGC	6 cut(s)	218, 286, 364, 422, 1083, 1231
BspANI	GGCC	3 cut(s)	731, 1208, 1297
BspCNI	CTCAG	4 cut(s)	619, 782, 1196, 1258
BspEI	TCCGGA	1 cut(s)	155
BspFNI	CGCG	3 cut(s)	656, 1000, 1233
BspLI	GGNNCC	4 cut(s)	875, 1080, 1146, 1259
BspOI	GCTAGC	1 cut(s)	465
BspPI	GGATC	2 cut(s)	1252, 1265
BspT104I	TTCGAA	1 cut(s)	1189
BspTNI	GGTCTC	1 cut(s)	777
BsrFI	RCCGGY	2 cut(s)	424, 550
BsrI	ACTGG	3 cut(s)	281, 1073, 1261
BssAI	RCCGGY	2 cut(s)	424, 550
BssECI	CCNNGG	1 cut(s)	1292
BssMI	GATC	4 cut(s)	663, 811, 927, 1257
BssSI	CACGAG	1 cut(s)	780
BssT1I	CCWWGG	1 cut(s)	1292
Bst2BI	CACGAG	1 cut(s)	780
Bst4CI	ACNGT	1 cut(s)	1110
Bst6I	CTCTTC	1 cut(s)	104
BstAPI	GCANNNNNTGC	1 cut(s)	1241
BstBI	TTCGAA	1 cut(s)	1189
BstC8I	GCNNGC	6 cut(s)	290, 463, 552, 1161, 1216, 1242
BstDEI	CTNAG	4 cut(s)	627, 769, 1183, 1266
BstF5I	GGATG	3 cut(s)	348, 981, 1063
BstFNI	CGCG	3 cut(s)	656, 1000, 1233
BstH2I	RGCGCY	2 cut(s)	551, 563
BstHHI	GCGC	5 cut(s)	550, 562, 745, 1002, 1235
BstKTI	GATC	4 cut(s)	666, 814, 930, 1260
BstMAI	GTCTC	3 cut(s)	301, 674, 777
BstMBI	GATC	4 cut(s)	663, 811, 927, 1257
BstMWI	GCNNNNNNNGC	5 cut(s)	363, 538, 547, 1241, 1294
BstSCI	CCNGG	3 cut(s)	496, 844, 869
BstUI	CGCG	3 cut(s)	656, 1000, 1233
BstV1I	GCAGC	4 cut(s)	836, 1112, 1231, 1282
BstX2I	RGATCY	2 cut(s)	927, 1257
BstYI	RGATCY	2 cut(s)	927, 1257
BsuRI	GGCC	3 cut(s)	731, 1208, 1297
BtsCI	GGATG	3 cut(s)	348, 981, 1063
BtsIMutI	CAGTG	3 cut(s)	1066, 1102, 1106
BtuMI	TCGCGA	1 cut(s)	656
Cac8I	GCNNGC	6 cut(s)	290, 463, 552, 1161, 1216, 1242
CfoI	GCGC	5 cut(s)	550, 562, 745, 1002, 1235
Cfr10I	RCCGGY	2 cut(s)	424, 550
Cfr13I	GGNCC	4 cut(s)	158, 238, 519, 1207
Csp6I	GTAC	2 cut(s)	975, 1199
CviAII	CATG	4 cut(s)	332, 755, 941, 1156
CviQI	GTAC	2 cut(s)	975, 1199
DdeI	CTNAG	4 cut(s)	627, 769, 1183, 1266
DpnI	GATC	4 cut(s)	665, 813, 929, 1259
DpnII	GATC	4 cut(s)	663, 811, 927, 1257
Eam1104I	CTCTTC	1 cut(s)	104
EarI	CTCTTC	1 cut(s)	104
Eco130I	CCWWGG	1 cut(s)	1292
Eco147I	AGGCCT	1 cut(s)	1297
Eco31I	GGTCTC	1 cut(s)	777
Eco47I	GGWCC	3 cut(s)	158, 238, 519
Eco57I	CTGAAG	1 cut(s)	767
EcoO109I	RGGNCCY	2 cut(s)	519, 1207
EcoT14I	CCWWGG	1 cut(s)	1292
EcoT22I	ATGCAT	1 cut(s)	348
ErhI	CCWWGG	1 cut(s)	1292
FaeI	CATG	4 cut(s)	335, 758, 944, 1159
FatI	CATG	4 cut(s)	331, 754, 940, 1155
FauI	CCCGC	1 cut(s)	1090
FauNDI	CATATG	1 cut(s)	956
Fnu4HI	GCNGC	5 cut(s)	850, 1101, 1245, 1271, 1289
FokI	GGATG	3 cut(s)	355, 968, 1070
Fsp4HI	GCNGC	5 cut(s)	850, 1101, 1245, 1271, 1289
FspBI	CTAG	6 cut(s)	35, 462, 672, 818, 1019, 1293
GlaI	GCGC	5 cut(s)	549, 561, 744, 1001, 1234
GluI	GCNGC	5 cut(s)	850, 1101, 1245, 1271, 1289
HaeII	RGCGCY	2 cut(s)	551, 563
HaeIII	GGCC	3 cut(s)	731, 1208, 1297
HapII	CCGG	8 cut(s)	156, 236, 373, 425, 497, 551, 846, 871
HhaI	GCGC	5 cut(s)	550, 562, 745, 1002, 1235
Hin1II	CATG	4 cut(s)	335, 758, 944, 1159
Hin6I	GCGC	5 cut(s)	548, 560, 743, 1000, 1233
HinP1I	GCGC	5 cut(s)	548, 560, 743, 1000, 1233
HinfI	GANTC	3 cut(s)	264, 402, 899
HpaII	CCGG	8 cut(s)	156, 236, 373, 425, 497, 551, 846, 871
HphI	GGTGA	5 cut(s)	207, 439, 466, 643, 701
Hpy166II	GTNNAC	2 cut(s)	112, 962
Hpy188I	TCNGA	4 cut(s)	283, 772, 1137, 1267
Hpy188III	TCNNGA	6 cut(s)	61, 156, 399, 577, 655, 703
Hpy8I	GTNNAC	2 cut(s)	112, 962
HpyCH4III	ACNGT	1 cut(s)	1110
HpyCH4IV	ACGT	1 cut(s)	1197
HpyF10VI	GCNNNNNNNGC	5 cut(s)	363, 538, 547, 1241, 1294
HpyF3I	CTNAG	4 cut(s)	627, 769, 1183, 1266
HpySE526I	ACGT	1 cut(s)	1197
Hsp92II	CATG	4 cut(s)	335, 758, 944, 1159
HspAI	GCGC	5 cut(s)	548, 560, 743, 1000, 1233
Kpn2I	TCCGGA	1 cut(s)	155
KroI	GCCGGC	1 cut(s)	550
KroNI	GCCGGC	1 cut(s)	552
Kzo9I	GATC	4 cut(s)	663, 811, 927, 1257
LmnI	GCTCC	6 cut(s)	9, 43, 186, 362, 873, 1144
Lsp1109I	GCAGC	4 cut(s)	836, 1112, 1231, 1282
LweI	GCATC	4 cut(s)	333, 355, 682, 1039
MaeI	CTAG	6 cut(s)	35, 462, 672, 818, 1019, 1293
MaeII	ACGT	1 cut(s)	1197
MalI	GATC	4 cut(s)	665, 813, 929, 1259
MboI	GATC	4 cut(s)	663, 811, 927, 1257
MboII	GAAGA	4 cut(s)	6, 91, 219, 617
MfeI	CAATTG	1 cut(s)	881
MflI	RGATCY	2 cut(s)	927, 1257
MluCI	AATT	8 cut(s)	137, 501, 793, 881, 909, 948, 969, 1223
MlyI	GAGTC	1 cut(s)	411
MmeI	TCCRAC	3 cut(s)	127, 465, 873
Mph1103I	ATGCAT	1 cut(s)	348
MroI	TCCGGA	1 cut(s)	155
MroNI	GCCGGC	1 cut(s)	550
MseI	TTAA	2 cut(s)	1226, 1300
MspI	CCGG	8 cut(s)	156, 236, 373, 425, 497, 551, 846, 871
MspR9I	CCNGG	3 cut(s)	498, 846, 871
MunI	CAATTG	1 cut(s)	881
MvnI	CGCG	3 cut(s)	656, 1000, 1233
MwoI	GCNNNNNNNGC	5 cut(s)	363, 538, 547, 1241, 1294
NaeI	GCCGGC	1 cut(s)	552
NciI	CCSGG	3 cut(s)	498, 846, 871
NdeI	CATATG	1 cut(s)	956
NdeII	GATC	4 cut(s)	663, 811, 927, 1257
NgoMIV	GCCGGC	1 cut(s)	550
NheI	GCTAGC	1 cut(s)	461
NlaIII	CATG	4 cut(s)	335, 758, 944, 1159
NlaIV	GGNNCC	4 cut(s)	875, 1080, 1146, 1259
NruI	TCGCGA	1 cut(s)	656
NsiI	ATGCAT	1 cut(s)	348
NspV	TTCGAA	1 cut(s)	1189
PceI	AGGCCT	1 cut(s)	1297
PdiI	GCCGGC	1 cut(s)	552
PfeI	GAWTC	2 cut(s)	264, 899
PfoI	TCCNGGA	2 cut(s)	496, 869
PkrI	GCNGC	5 cut(s)	851, 1102, 1246, 1272, 1290
PleI	GAGTC	1 cut(s)	410
PpsI	GAGTC	1 cut(s)	410
PpuMI	RGGWCCY	1 cut(s)	519
PshBI	ATTAAT	1 cut(s)	1226
Psp5II	RGGWCCY	1 cut(s)	519
PspN4I	GGNNCC	4 cut(s)	875, 1080, 1146, 1259
PspPI	GGNCC	4 cut(s)	158, 238, 519, 1207
PspPPI	RGGWCCY	1 cut(s)	519
PsuI	RGATCY	2 cut(s)	927, 1257
RruI	TCGCGA	1 cut(s)	656
RsaI	GTAC	2 cut(s)	976, 1200
RsaNI	GTAC	2 cut(s)	975, 1199
SaqAI	TTAA	2 cut(s)	1226, 1300
SatI	GCNGC	5 cut(s)	850, 1101, 1245, 1271, 1289
Sau3AI	GATC	4 cut(s)	663, 811, 927, 1257
Sau96I	GGNCC	4 cut(s)	158, 238, 519, 1207
SchI	GAGTC	1 cut(s)	411
ScrFI	CCNGG	3 cut(s)	498, 846, 871
SfaNI	GCATC	4 cut(s)	333, 355, 682, 1039
SfuI	TTCGAA	1 cut(s)	1189
SgrAI	CRCCGGYG	1 cut(s)	424
SinI	GGWCC	3 cut(s)	158, 238, 519
SmlI	CTYRAG	4 cut(s)	170, 385, 701, 1009
SmoI	CTYRAG	4 cut(s)	170, 385, 701, 1009
Sse9I	AATT	8 cut(s)	137, 501, 793, 881, 909, 948, 969, 1223
SseBI	AGGCCT	1 cut(s)	1297
SsiI	CCGC	6 cut(s)	218, 286, 364, 422, 1083, 1231
SspMI	CTAG	6 cut(s)	35, 462, 672, 818, 1019, 1293
StuI	AGGCCT	1 cut(s)	1297
StyD4I	CCNGG	3 cut(s)	496, 844, 869
StyI	CCWWGG	1 cut(s)	1292
TaaI	ACNGT	1 cut(s)	1110
TaiI	ACGT	1 cut(s)	1200
TaqI	TCGA	5 cut(s)	596, 841, 902, 1119, 1189
TasI	AATT	8 cut(s)	137, 501, 793, 881, 909, 948, 969, 1223
TfiI	GAWTC	2 cut(s)	264, 899
Tru1I	TTAA	2 cut(s)	1226, 1300
Tru9I	TTAA	2 cut(s)	1226, 1300
TscAI	CASTG	3 cut(s)	1073, 1102, 1113
TseI	GCWGC	5 cut(s)	849, 1100, 1244, 1270, 1288
TspDTI	ATGAA	3 cut(s)	853, 957, 1081
TspRI	CASTG	3 cut(s)	1073, 1102, 1113
VpaK11BI	GGWCC	3 cut(s)	158, 238, 519
VspI	ATTAAT	1 cut(s)	1226
XapI	RAATTY	2 cut(s)	501, 793
XcmI	CCANNNNNNNNNTGG	1 cut(s)	947
XmaJI	CCTAGG	1 cut(s)	1292
XspI	CTAG	6 cut(s)	35, 462, 672, 818, 1019, 1293
Zsp2I	ATGCAT	1 cut(s)	348

Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.