Basic Information

Type: gene

Biological Identity

Species

malus_domestica

Chromosome

Chr10

Orthogroup ID

OG0003367

Physical Location & Seq

Genomic Coordinates Forward (+)

23528346 .. 23539536

Gene Structure 11191 bp

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UTR

Exon/CDS

Intron

Transcript / Protein ID

MD10G1147300.v1.1.491

Sequence Viewer

CDS Protein Promoter (2k)

Length: 1254 bp

ATGGCCTTCTCCGAGTTCCGGCCGCTGGACGAGAAGGTCCTCATAGAGTACATAAAGGCCACGCCTTCTCTCGCTTCTAAGCTCGGCAACAAGTTCGACAACTTAACCATCAAAGAAGTTGGCGATGGCAATCTCAACTTCGTCTTCATCGTCGTTGGTTCTTCTGGTTCTTTCGTCATCAAGCAGGCTCTTCCATATATCCGTTTGATTGGTGAGTCATGGCCAATGACAAAGGAAAGAGCATATTTTGAGGCATTGGCACTTAAAGAGCATGGAAGTTTGAGTCCTGATCATGTTCCTGAAGTGTATCATTTCGATCGGACCATGTCTTTGATCGGCATGCACTATTTGGAGCCCCCGCATATCATACTGAGAAAAGGGTTGATTGCTGGAGTTGAGTACCCCTTGCTGGCCGACCACATGTCCGACTATATTGCAAAGACTCTGTTCTTCACATCCCTTCTGTATCACAATACCACAGACCACAAAAAAGCTGTTGCCGAATTTTGTGGCAATGTGGAGTTGTGCAGGCTCACTGAGCAGGTTGTTTTTTCTGATCCTTACAAAGTATCTCAATATAACCGATGGACTTCTCCTTATCTTGATTCGGATGCTGAGGCTGTGCGGGGGGATAATGCTTTGAAGCTTGAAGTTGCTGAGTTGAAATCCTTGTTCTGTGAGAGAGCACAAGCCCTAGTACATGGAGATCTTCACACTAGTTCTGTAATGGTGACTCATGATTCAACTCAAGTTATAGATCCAGAGTTTGCATTTTATGGACCAATGGGTTTTGATATTGGAGCTTTTCTGGGCAACTTGATTTTGGCTTTCTATGCACAAGATGGGCATGCTAATGACCAGAATGATCGAAAAGCATACAAGGCTTGGATTTTGAGGACAATTGAAAACACTTGGAACCTTTTCGACAGAAAATTCCTTGCACTATGGGATGCGAACAAAGATTCTGGCGACGCATATCTACCTGCAATTTATAACAACCCTGAGCTTGTACAGCTTGTACAAAAGAAATTTATTAAAGATCTGTTTCATGACAGTCTTGGATTTGGTGCTGCAAAAATGATAAGGCGAATCGTTGGAGTTGCTCATGTTGAAGATTTTGAGTCAATAGCGGATGCCAGCAAGCGGGCGGGTTGTGAGCGTCGAGCTCTTGAGTTAGCAAAGCTCCTTCTCAAGGAGAGGAAAAAATTTCAGGACATTAATGAAGTTATTTCAGCAATTCTTCAACACCAGTAA

Functional Annotation

Gene Ontology

Molecular Function
Biological Process
Cellular Component

GO:0000096 GO:0000097 GO:0000302 GO:0003674 GO:0003824 GO:0005488 GO:0005515 GO:0005575 GO:0005622 GO:0005623 GO:0005737 GO:0005829 GO:0006082 GO:0006520 GO:0006555 GO:0006790 GO:0006793 GO:0006796 GO:0006807 GO:0006950 GO:0006979 GO:0008150 GO:0008152 GO:0008652 GO:0009058 GO:0009066 GO:0009067 GO:0009086 GO:0009719 GO:0009723 GO:0009725 GO:0009987 GO:0010033 GO:0010035 GO:0010038 GO:0010039 GO:0016053 GO:0016301 GO:0016310 GO:0016740 GO:0016772 GO:0016773 GO:0017144 GO:0019509 GO:0019752 GO:0032870 GO:0033554 GO:0034599 GO:0034614 GO:0035690 GO:0042221 GO:0042493 GO:0042802 GO:0043094 GO:0043102 GO:0043436 GO:0044237 GO:0044238 GO:0044249 GO:0044272 GO:0044281 GO:0044283 GO:0044424 GO:0044444 GO:0044464 GO:0046394 GO:0046522 GO:0050896 GO:0051716 GO:0070887 GO:0071241 GO:0071248 GO:0071265 GO:0071267 GO:0071281 GO:0071310 GO:0071369 GO:0071495 GO:0071704 GO:0071731 GO:0071732 GO:0097366 GO:1901564 GO:1901566 GO:1901576 GO:1901605 GO:1901607 GO:1901698 GO:1901699 GO:1901700 GO:1901701 GO:1902170

KEGG Pathways

Metabolic & Signaling

ko00270 ko01100 map00270 map01100

Pfam Domains

Protein Families

APH

Protein Analysis

418

Amino Acids

47.23

Weight (kDa)

5.94

Isoelectric Point (pI)

37.69

Instability Index

Protein Domains (Pfam)

Domain Name	Pfam ID	Position	E-value	Description
APH	PF01636	36 - 272	4.8e-11	Phosphotransferase enzyme family

Hydrophobicity Profile (Kyte-Doolittle)

AI Structure Prediction Report

Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter

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Align Labels (Cladogram)

Image

Tree File

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Publication-ready

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Orthologous Genes (Group: OG0003367)

Species	Orthologous Gene IDs
arabidopsis_thaliana	AT1G49820
fragaria_vesca	FvH4_2g05040
malus_domestica	MD10G1098200.v1.1 MD10G1098700.v1.1 MD10G1147300.v1.1
prunus_persica	Prupe.7G233900_v2.0.a1 Prupe.8G136000_v2.0.a1
pyrus_communis	pycom10g08390
rosa_chinensis	RchiOBHm_Chr2g0122061 RchiOBHm_Chr6g0254911 RchiOBHm_Chr6g0254921
rosa_laevigata	RLG00000014878 RLG00000014883
rosa_multiflora	Rmu_sc0000016.1_g000011 Rmu_sc0003880.1_g000001 Rmu_sc0010925.1_g000019
rosa_roxburghii	Rroxscaffold_2G00122040 Rroxscaffold_7G00210480
rosa_rugosa	Rorug02G0236200 Rorug02G0236300 Rorug05G0555300
rosa_samantha	Rh2AG292600 Rh2BG303200 Rh2CG281700 Rh2DG316800 Rh6AG072700 Rh6BG064800 Rh6BG065000 Rh6CG063900 Rh6CG064800 Rh6DG061000 Rh6DG061800
rosa_wichuraiana	Rw0G002700 Rw2G023480 Rw6G006330 Rw6G006340

Restriction Enzyme Sites

1 / 10

Enzyme	Recognition Site	Cut Count	Positions (bp)
AanI	TTATAA	1 cut(s)	993
AasI	GACNNNNNNGTC	1 cut(s)	35
Acc36I	ACCTGC	2 cut(s)	532, 991
AciI	CCGC	6 cut(s)	23, 359, 625, 1130, 1144, 1148
AclWI	GGATC	2 cut(s)	551, 752
AcoI	YGGCCR	3 cut(s)	20, 221, 411
AcsI	RAATTY	4 cut(s)	503, 932, 1028, 1205
AcuI	CTGAAG	1 cut(s)	321
AfaI	GTAC	5 cut(s)	50, 401, 699, 1011, 1020
AfiI	CCNNNNNNNGG	5 cut(s)	18, 25, 409, 1143, 1192
AflIII	ACRYGT	1 cut(s)	420
AgsI	TTSAA	7 cut(s)	643, 650, 664, 744, 905, 1112, 1244
AhdI	GACNNNNNGTC	1 cut(s)	421
AhlI	ACTAGT	1 cut(s)	716
AluBI	AGCT	8 cut(s)	82, 494, 646, 803, 1006, 1015, 1166, 1183
AluI	AGCT	8 cut(s)	82, 494, 646, 803, 1006, 1015, 1166, 1183
Alw21I	GWGCWC	2 cut(s)	688, 1168
AlwI	GGATC	2 cut(s)	551, 752
AoxI	GGCC	5 cut(s)	3, 20, 57, 221, 411
ApeKI	GCWGC	1 cut(s)	1070
ApoI	RAATTY	4 cut(s)	503, 932, 1028, 1205
ArsI	GACNNNNNNTTYG	2 cut(s)	313, 345
AseI	ATTAAT	1 cut(s)	1218
Asp700I	GAANNNNTTC	1 cut(s)	920
AspS9I	GGNCC	3 cut(s)	37, 321, 779
AsuHPI	GGTGA	2 cut(s)	224, 742
AvaII	GGWCC	3 cut(s)	37, 321, 779
BalI	TGGCCA	1 cut(s)	223
BanII	GRGCYC	2 cut(s)	357, 1168
BbsI	GAAGAC	1 cut(s)	136
Bbv12I	GWGCWC	2 cut(s)	688, 1168
BbvCI	CCTCAGC	1 cut(s)	615
BbvI	GCAGC	1 cut(s)	1057
BccI	CCATC	4 cut(s)	116, 119, 579, 836
BcgI	CGANNNNNNTGC	4 cut(s)	76, 110, 416, 450
BclI	TGATCA	1 cut(s)	289
BcuI	ACTAGT	1 cut(s)	716
BfaI	CTAG	2 cut(s)	695, 717
BfuAI	ACCTGC	2 cut(s)	532, 991
BglII	AGATCT	2 cut(s)	706, 1039
BisI	GCNGC	2 cut(s)	23, 1071
BlsI	GCNGC	2 cut(s)	24, 1072
Bme18I	GGWCC	3 cut(s)	37, 321, 779
BmeRI	GACNNNNNGTC	1 cut(s)	421
BmgT120I	GGNCC	3 cut(s)	37, 321, 779
BmiI	GGNNCC	2 cut(s)	354, 917
BmsI	GCATC	3 cut(s)	601, 940, 1123
BpiI	GAAGAC	1 cut(s)	136
BpmI	CTGGAG	1 cut(s)	411
Bpu10I	CCTNAGC	2 cut(s)	615, 1002
BpuEI	CTTGAG	3 cut(s)	732, 1175, 1190
BsaBI	GATNNNNATC	1 cut(s)	129
Bsc4I	CCNNNNNNNGG	5 cut(s)	18, 25, 409, 1143, 1192
Bse1I	ACTGG	1 cut(s)	1249
Bse3DI	GCAATG	1 cut(s)	520
Bse8I	GATNNNNATC	1 cut(s)	129
BseGI	GGATG	4 cut(s)	455, 616, 955, 1138
BseJI	GATNNNNATC	1 cut(s)	129
BseLI	CCNNNNNNNGG	5 cut(s)	18, 25, 409, 1143, 1192
BseMI	GCAATG	1 cut(s)	520
BseMII	CTCAG	5 cut(s)	362, 528, 606, 648, 993
BseNI	ACTGG	1 cut(s)	1249
BseX3I	CGGCCG	1 cut(s)	20
BseXI	GCAGC	1 cut(s)	1057
BsgI	GTGCAG	1 cut(s)	547
Bsh1285I	CGRYCG	2 cut(s)	23, 319
BshFI	GGCC	5 cut(s)	5, 22, 59, 223, 413
BsiEI	CGRYCG	2 cut(s)	23, 319
BsiHKAI	GWGCWC	2 cut(s)	688, 1168
BsiSI	CCGG	1 cut(s)	19
BslI	CCNNNNNNNGG	5 cut(s)	18, 25, 409, 1143, 1192
BsnI	GGCC	5 cut(s)	5, 22, 59, 223, 413
Bsp1286I	GDGCHC	3 cut(s)	357, 688, 1168
Bsp1407I	TGTACA	2 cut(s)	1009, 1018
Bsp143I	GATC	8 cut(s)	289, 316, 333, 556, 706, 757, 865, 1039
BspACI	CCGC	6 cut(s)	23, 359, 625, 1130, 1144, 1148
BspANI	GGCC	5 cut(s)	5, 22, 59, 223, 413
BspCNI	CTCAG	5 cut(s)	363, 529, 607, 649, 994
BspHI	TCATGA	2 cut(s)	736, 1048
BspLI	GGNNCC	2 cut(s)	354, 917
BspMI	ACCTGC	2 cut(s)	532, 991
BspPI	GGATC	2 cut(s)	551, 752
BspQI	GCTCTTC	1 cut(s)	195
BsrDI	GCAATG	1 cut(s)	520
BsrGI	TGTACA	2 cut(s)	1009, 1018
BsrI	ACTGG	1 cut(s)	1249
BssMI	GATC	8 cut(s)	289, 316, 333, 556, 706, 757, 865, 1039
Bst4CI	ACNGT	1 cut(s)	1055
Bst6I	CTCTTC	1 cut(s)	195
BstAUI	TGTACA	2 cut(s)	1009, 1018
BstC8I	GCNNGC	8 cut(s)	186, 341, 411, 530, 849, 1138, 1142, 1146
BstDEI	CTNAG	6 cut(s)	78, 371, 537, 615, 657, 1002
BstENI	CCTNNNNNAGG	1 cut(s)	1190
BstF5I	GGATG	4 cut(s)	455, 616, 955, 1138
BstKTI	GATC	8 cut(s)	292, 319, 336, 559, 709, 760, 868, 1042
BstMBI	GATC	8 cut(s)	289, 316, 333, 556, 706, 757, 865, 1039
BstMCI	CGRYCG	2 cut(s)	23, 319
BstMWI	GCNNNNNNNGC	4 cut(s)	538, 833, 881, 1012
BstNSI	RCATGY	3 cut(s)	343, 424, 851
BstV1I	GCAGC	1 cut(s)	1057
BstV2I	GAAGAC	1 cut(s)	136
BstX2I	RGATCY	3 cut(s)	706, 757, 1039
BstYI	RGATCY	3 cut(s)	706, 757, 1039
BstZI	CGGCCG	1 cut(s)	20
BsuRI	GGCC	5 cut(s)	5, 22, 59, 223, 413
BtgZI	GCGATG	1 cut(s)	138
BtsCI	GGATG	4 cut(s)	455, 616, 955, 1138
BtsIMutI	CAGTG	1 cut(s)	534
BveI	ACCTGC	2 cut(s)	532, 991
Cac8I	GCNNGC	8 cut(s)	186, 341, 411, 530, 849, 1138, 1142, 1146
CciI	TCATGA	2 cut(s)	736, 1048
Cfr13I	GGNCC	3 cut(s)	37, 321, 779
CseI	GACGC	2 cut(s)	980, 1148
Csp6I	GTAC	5 cut(s)	49, 400, 698, 1010, 1019
CviQI	GTAC	5 cut(s)	49, 400, 698, 1010, 1019
DdeI	CTNAG	6 cut(s)	78, 371, 537, 615, 657, 1002
DpnI	GATC	8 cut(s)	291, 318, 335, 558, 708, 759, 867, 1041
DpnII	GATC	8 cut(s)	289, 316, 333, 556, 706, 757, 865, 1039
DrdI	GACNNNNNNGTC	1 cut(s)	35
DriI	GACNNNNNGTC	1 cut(s)	421
DseDI	GACNNNNNNGTC	1 cut(s)	35
EaeI	YGGCCR	3 cut(s)	20, 221, 411
EagI	CGGCCG	1 cut(s)	20
Eam1104I	CTCTTC	1 cut(s)	195
Eam1105I	GACNNNNNGTC	1 cut(s)	421
EarI	CTCTTC	1 cut(s)	195
Ecl136II	GAGCTC	1 cut(s)	1166
EclXI	CGGCCG	1 cut(s)	20
Eco24I	GRGCYC	2 cut(s)	357, 1168
Eco47I	GGWCC	3 cut(s)	37, 321, 779
Eco52I	CGGCCG	1 cut(s)	20
Eco53kI	GAGCTC	1 cut(s)	1166
Eco57I	CTGAAG	1 cut(s)	321
EcoICRI	GAGCTC	1 cut(s)	1166
EcoNI	CCTNNNNNAGG	1 cut(s)	1190
EcoO109I	RGGNCCY	1 cut(s)	37
EcoT38I	GRGCYC	2 cut(s)	357, 1168
FauI	CCCGC	4 cut(s)	366, 618, 1137, 1141
FbaI	TGATCA	1 cut(s)	289
Fnu4HI	GCNGC	2 cut(s)	23, 1071
FokI	GGATG	4 cut(s)	442, 623, 962, 1145
FriOI	GRGCYC	2 cut(s)	357, 1168
Fsp4HI	GCNGC	2 cut(s)	23, 1071
FspBI	CTAG	2 cut(s)	695, 717
GluI	GCNGC	2 cut(s)	23, 1071
GsuI	CTGGAG	1 cut(s)	411
HaeIII	GGCC	5 cut(s)	5, 22, 59, 223, 413
HapII	CCGG	1 cut(s)	19
HgaI	GACGC	2 cut(s)	980, 1148
HindIII	AAGCTT	1 cut(s)	644
HinfI	GANTC	9 cut(s)	215, 283, 442, 605, 733, 740, 962, 1089, 1121
HpaII	CCGG	1 cut(s)	19
HphI	GGTGA	2 cut(s)	224, 742
Hpy188I	TCNGA	5 cut(s)	13, 321, 427, 556, 610
Hpy188III	TCNNGA	8 cut(s)	287, 299, 602, 737, 761, 1049, 1169, 1211
Hpy99I	CGWCG	3 cut(s)	155, 974, 1164
HpyAV	CCTTC	5 cut(s)	16, 28, 75, 470, 1196
HpyCH4III	ACNGT	1 cut(s)	1055
HpyCH4V	TGCA	8 cut(s)	343, 437, 528, 770, 836, 941, 986, 1073
HpyF10VI	GCNNNNNNNGC	4 cut(s)	538, 833, 881, 1012
HpyF3I	CTNAG	6 cut(s)	78, 371, 537, 615, 657, 1002
Ksp22I	TGATCA	1 cut(s)	289
Kzo9I	GATC	8 cut(s)	289, 316, 333, 556, 706, 757, 865, 1039
LguI	GCTCTTC	1 cut(s)	195
LmnI	GCTCC	3 cut(s)	352, 800, 1188
Lsp1109I	GCAGC	1 cut(s)	1057
LweI	GCATC	3 cut(s)	601, 940, 1123
MaeI	CTAG	2 cut(s)	695, 717
MaeIII	GTNAC	1 cut(s)	730
MalI	GATC	8 cut(s)	291, 318, 335, 558, 708, 759, 867, 1041
MboI	GATC	8 cut(s)	289, 316, 333, 556, 706, 757, 865, 1039
MboII	GAAGA	7 cut(s)	136, 153, 182, 442, 701, 1124, 1232
MfeI	CAATTG	1 cut(s)	900
MflI	RGATCY	3 cut(s)	706, 757, 1039
MhlI	GDGCHC	3 cut(s)	357, 688, 1168
MlsI	TGGCCA	1 cut(s)	223
MluCI	AATT	7 cut(s)	503, 900, 932, 987, 1028, 1205, 1236
MluNI	TGGCCA	1 cut(s)	223
MlyI	GAGTC	5 cut(s)	224, 292, 436, 727, 1130
MmeI	TCCRAC	2 cut(s)	450, 1075
MnlI	CCTC	5 cut(s)	50, 244, 610, 888, 1191
Mox20I	TGGCCA	1 cut(s)	223
MroXI	GAANNNNTTC	1 cut(s)	920
MscI	TGGCCA	1 cut(s)	223
MseI	TTAA	4 cut(s)	104, 264, 1035, 1218
MslI	CAYNNNNRTG	1 cut(s)	852
Msp20I	TGGCCA	1 cut(s)	223
MspA1I	CMGCKG	1 cut(s)	25
MspI	CCGG	1 cut(s)	19
MunI	CAATTG	1 cut(s)	900
MwoI	GCNNNNNNNGC	4 cut(s)	538, 833, 881, 1012
NdeII	GATC	8 cut(s)	289, 316, 333, 556, 706, 757, 865, 1039
NlaIV	GGNNCC	2 cut(s)	354, 917
NmeAIII	GCCGAG	1 cut(s)	63
NmuCI	GTSAC	1 cut(s)	730
NspI	RCATGY	3 cut(s)	343, 424, 851
PaeI	GCATGC	2 cut(s)	343, 851
PagI	TCATGA	2 cut(s)	736, 1048
PciI	ACATGT	1 cut(s)	420
PciSI	GCTCTTC	1 cut(s)	195
PcsI	WCGNNNNNNNCGW	1 cut(s)	147
PdmI	GAANNNNTTC	1 cut(s)	920
PfeI	GAWTC	4 cut(s)	605, 740, 962, 1089
PflFI	GACNNNGTC	1 cut(s)	325
PkrI	GCNGC	2 cut(s)	24, 1072
Ple19I	CGATCG	1 cut(s)	319
PleI	GAGTC	5 cut(s)	223, 291, 436, 727, 1129
PpsI	GAGTC	5 cut(s)	223, 291, 436, 727, 1129
PpuMI	RGGWCCY	1 cut(s)	37
PscI	ACATGT	1 cut(s)	420
PshBI	ATTAAT	1 cut(s)	1218
PsiI	TTATAA	1 cut(s)	993
Psp124BI	GAGCTC	1 cut(s)	1168
Psp5II	RGGWCCY	1 cut(s)	37
PspN4I	GGNNCC	2 cut(s)	354, 917
PspPI	GGNCC	3 cut(s)	37, 321, 779
PspPPI	RGGWCCY	1 cut(s)	37
PsuI	RGATCY	3 cut(s)	706, 757, 1039
PsyI	GACNNNGTC	1 cut(s)	325
PvuI	CGATCG	1 cut(s)	319
RsaI	GTAC	5 cut(s)	50, 401, 699, 1011, 1020
RsaNI	GTAC	5 cut(s)	49, 400, 698, 1010, 1019
RseI	CAYNNNNRTG	1 cut(s)	852
SacI	GAGCTC	1 cut(s)	1168
SapI	GCTCTTC	1 cut(s)	195
SaqAI	TTAA	4 cut(s)	104, 264, 1035, 1218
SatI	GCNGC	2 cut(s)	23, 1071
Sau3AI	GATC	8 cut(s)	289, 316, 333, 556, 706, 757, 865, 1039
Sau96I	GGNCC	3 cut(s)	37, 321, 779
SchI	GAGTC	5 cut(s)	224, 292, 436, 727, 1130
SduI	GDGCHC	3 cut(s)	357, 688, 1168
SfaNI	GCATC	3 cut(s)	601, 940, 1123
SinI	GGWCC	3 cut(s)	37, 321, 779
SmiMI	CAYNNNNRTG	1 cut(s)	852
SmlI	CTYRAG	3 cut(s)	747, 1169, 1190
SmoI	CTYRAG	3 cut(s)	747, 1169, 1190
SpeI	ACTAGT	1 cut(s)	716
SphI	GCATGC	2 cut(s)	343, 851
Sse9I	AATT	7 cut(s)	503, 900, 932, 987, 1028, 1205, 1236
SsiI	CCGC	6 cut(s)	23, 359, 625, 1130, 1144, 1148
SspMI	CTAG	2 cut(s)	695, 717
SstI	GAGCTC	1 cut(s)	1168
TaaI	ACNGT	1 cut(s)	1055
TaqI	TCGA	5 cut(s)	96, 315, 868, 924, 1162
TasI	AATT	7 cut(s)	503, 900, 932, 987, 1028, 1205, 1236
TatI	WGTACW	4 cut(s)	48, 697, 1009, 1018
TauI	GCSGC	1 cut(s)	25
TfiI	GAWTC	4 cut(s)	605, 740, 962, 1089
Tru1I	TTAA	4 cut(s)	104, 264, 1035, 1218
Tru9I	TTAA	4 cut(s)	104, 264, 1035, 1218
TscAI	CASTG	1 cut(s)	541
TseFI	GTSAC	1 cut(s)	730
TseI	GCWGC	1 cut(s)	1070
Tsp45I	GTSAC	1 cut(s)	730
TspDTI	ATGAA	3 cut(s)	136, 1037, 1236
TspGWI	ACGGA	1 cut(s)	191
TspRI	CASTG	1 cut(s)	541
Tth111I	GACNNNGTC	1 cut(s)	325
VpaK11BI	GGWCC	3 cut(s)	37, 321, 779
VspI	ATTAAT	1 cut(s)	1218
XagI	CCTNNNNNAGG	1 cut(s)	1190
XapI	RAATTY	4 cut(s)	503, 932, 1028, 1205
XceI	RCATGY	3 cut(s)	343, 424, 851
XmnI	GAANNNNTTC	1 cut(s)	920
XspI	CTAG	2 cut(s)	695, 717

Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.