MD05G1110800.v1.1

DUF21 domain-containing protein

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
malus_domestica
Chr05
OG0007184
Physical Location & Seq
Forward (+)
22806079 .. 22810028
3950 bp
Loading structure...
UTR
Exon/CDS
Intron
MD05G1110800.v1.1.491

Sequence Viewer

Length: 1281 bp
ATGGCGGTGGAGTACGAGTGCTGCACCAGTGGATTCTTCATTCACATAGTGGTCATCGTGCTGCTGGTGCTGTTCGCGGGGCTAATGTCCGGGCTCACCTTGGGCCTCATGTCCATGAGCCTCGTCGATCTCGAAGTCCTCGCCAAGTCCGGGACGCCGAAGGATCGCAAGCACGCCGCGAAGATATTACCAGTTGTCAAAAACCAGCATCTGTTGCTTTGCACCCTGCTGATTTGCAATGCTGCTGCAATGGAGACACTCCCAATTTTTCTTGATGGTTTGTTGAAAGCTTGGGGTGCAATCCTCATTTCTGTGACACTGATTCTTCTGTTTGGCGAGATTATACCACAATCTGTTTGTTCCCGATATGGTTTGGCTATAGGCGCAACAGTGGCTCCAGTTGTCCGTGTTCTTGTTTGGATCTGCTTTCCTGTTGCATATCCTATTAGTAAGCTATTAGACTTTCTGTTGGGCCATGGACATGTAGCTCTCTTTCGCAGAGCTGAGTTGAAAACGCTTGTAGATATGCATGGCAATGAGGCCGGAAAAGGCGGAGAGTTGACACATGATGAAACAACCATTATTGCCGGAGCACTTGGACTCTCTGAGAAAACGGCTCGTGATGCCATGACTCCTATAGCTGAAACTTTTGCGATCGATATCAATGCCAAGCTTGACAGGAATTTGATGAATCTAATATTGGAGAAAGGGCATAGCAGAGTACCGGTTTATTATGAGGAGCCGACAAATATTATTGGACTCATCCTGGTAAAAAATTTGTTAACAGTGAACCCAGAAGAAGAAGTACCTGTAAAGAATGTCACTATACGCAAGATTCCAAGGGTTCCAGAAATGTTGCCTTTATATGACATATTGAATGAGTTTCAAAAGGGTCACAGTCACATGGCTATTGTTGTAAGAAGGTGCAATAAGAATACGGAGCAGACTAATGGCATTCCGGGTGACAGTCCAGTGAAAGAGGTGAAAGTCGACATTGACGGTGAAAAGCCTCTTCACGAGAAGTTGAAGAGCAAAAGATCACTGCAGAAGTGGAAGAGCTTTCCGAATTCAAACAGTGCAAATAATTCATACAGGACCGGGTCCAGAAGCAAGAAATGGACAAAGGAGATGTACTCAGACATCCTGCAGACTGATGGTGAGCTCCCCAAACTACCTGAAGAGGAAGAGGCTGTTGGCATCATAACAATGGAAGATGTTATCGAAGAACTTTTACAGGAGGAGATTTTTGACGAGACTGACCATCAGTTCGAGGACTCATAA
Functional Annotation
Gene Ontology
Molecular Function
Biological Process
Cellular Component
GO:0005575 GO:0005623 GO:0005886 GO:0016020 GO:0044464 GO:0071944
KEGG Pathways
Metabolic & Signaling
No pathways identified.
Pfam Domains
Protein Families
DUF21

Protein Analysis

427

Amino Acids

47.27

Weight (kDa)

5.63

Isoelectric Point (pI)

46.29

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
CNNM PF01595 18 - 189 4e-35 Cyclin M transmembrane N-terminal domain
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
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Publication-ready
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Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AccI GTMKAC 1 cut(s) 990
AccII CGCG 2 cut(s) 77, 179
AciI CCGC 4 cut(s) 5, 77, 177, 552
AclWI GGATC 2 cut(s) 171, 428
AcsI RAATTY 3 cut(s) 682, 775, 1066
AcuI CTGAAG 1 cut(s) 1197
AcyI GRCGYC 1 cut(s) 155
AdeI CACNNNGTG 1 cut(s) 49
AfaI GTAC 4 cut(s) 14, 723, 807, 1133
AfiI CCNNNNNNNGG 1 cut(s) 150
AflIII ACRYGT 1 cut(s) 481
AgeI ACCGGT 1 cut(s) 724
AgsI TTSAA 6 cut(s) 286, 511, 877, 887, 1027, 1071
AjnI CCWGG 1 cut(s) 765
AjuI GAANNNNNNNTTGG 4 cut(s) 683, 715, 1176, 1208
AluBI AGCT 8 cut(s) 290, 454, 488, 503, 641, 673, 1059, 1162
AluI AGCT 8 cut(s) 290, 454, 488, 503, 641, 673, 1059, 1162
Alw21I GWGCWC 2 cut(s) 595, 1164
Alw26I GTCTC 2 cut(s) 248, 1247
AlwI GGATC 2 cut(s) 171, 428
AlwNI CAGNNNCTG 1 cut(s) 211
AoxI GGCC 3 cut(s) 103, 472, 540
ApeKI GCWGC 4 cut(s) 21, 61, 242, 245
ApoI RAATTY 3 cut(s) 682, 775, 1066
ArsI GACNNNNNNTTYG 1 cut(s) 1250
AsiGI ACCGGT 1 cut(s) 724
AspLEI GCGC 1 cut(s) 386
AspS9I GGNCC 4 cut(s) 103, 472, 1095, 1101
AsuC2I CCSGG 4 cut(s) 91, 151, 960, 1099
AsuHPI GGTGA 5 cut(s) 88, 974, 994, 1013, 1169
AvaII GGWCC 2 cut(s) 1095, 1101
BanII GRGCYC 2 cut(s) 96, 1164
BarI GAAGNNNNNNTAC 4 cut(s) 789, 821, 1215, 1247
BauI CACGAG 2 cut(s) 618, 1016
Bbv12I GWGCWC 2 cut(s) 595, 1164
BbvI GCAGC 4 cut(s) 8, 48, 229, 232
BccI CCATC 3 cut(s) 269, 1148, 1269
BceAI ACGGC 1 cut(s) 630
BcgI CGANNNNNNTGC 2 cut(s) 647, 681
BciT130I CCWGG 1 cut(s) 767
BcnI CCSGG 4 cut(s) 91, 151, 960, 1099
BcoDI GTCTC 2 cut(s) 248, 1247
BfmI CTRYAG 4 cut(s) 378, 636, 1043, 1145
BisI GCNGC 5 cut(s) 22, 62, 177, 243, 246
BlsI GCNGC 5 cut(s) 23, 63, 178, 244, 247
Bme1390I CCNGG 5 cut(s) 91, 151, 767, 960, 1099
Bme18I GGWCC 2 cut(s) 1095, 1101
BmgT120I GGNCC 4 cut(s) 103, 472, 1095, 1101
BmiI GGNNCC 4 cut(s) 396, 741, 846, 1102
BmrFI CCNGG 5 cut(s) 91, 151, 767, 960, 1099
BmsI GCATC 3 cut(s) 217, 613, 1206
BplI GAGNNNNNCTC 2 cut(s) 1118, 1150
BpmI CTGGAG 1 cut(s) 381
BpuMI CCSGG 4 cut(s) 91, 151, 960, 1099
Bsa29I ATCGAT 1 cut(s) 657
BsaBI GATNNNNATC 1 cut(s) 659
BsaHI GRCGYC 1 cut(s) 155
BsaJI CCNNGG 3 cut(s) 99, 475, 839
BsaWI WCCGGW 1 cut(s) 724
BsaXI ACNNNNNCTCC 3 cut(s) 32, 379, 409
Bsc4I CCNNNNNNNGG 1 cut(s) 150
Bse118I RCCGGY 1 cut(s) 724
Bse1I ACTGG 4 cut(s) 27, 191, 398, 971
Bse3DI GCAATG 3 cut(s) 244, 255, 541
Bse8I GATNNNNATC 1 cut(s) 659
BseBI CCWGG 1 cut(s) 767
BseCI ATCGAT 1 cut(s) 657
BseDI CCNNGG 3 cut(s) 99, 475, 839
BseGI GGATG 2 cut(s) 762, 1140
BseJI GATNNNNATC 1 cut(s) 659
BseLI CCNNNNNNNGG 1 cut(s) 150
BseMI GCAATG 3 cut(s) 244, 255, 541
BseMII CTCAG 3 cut(s) 495, 597, 1149
BseNI ACTGG 4 cut(s) 27, 191, 398, 971
BseRI GAGGAG 2 cut(s) 752, 1253
BseXI GCAGC 4 cut(s) 8, 48, 229, 232
BsgI GTGCAG 1 cut(s) 7
Bsh1236I CGCG 2 cut(s) 77, 179
Bsh1285I CGRYCG 1 cut(s) 657
BshFI GGCC 3 cut(s) 105, 474, 542
BshTI ACCGGT 1 cut(s) 724
BshVI ATCGAT 1 cut(s) 657
BsiEI CGRYCG 1 cut(s) 657
BsiHKAI GWGCWC 2 cut(s) 595, 1164
BsiSI CCGG 7 cut(s) 90, 150, 543, 588, 725, 959, 1098
BslFI GGGAC 1 cut(s) 166
BslI CCNNNNNNNGG 1 cut(s) 150
BsmAI GTCTC 2 cut(s) 248, 1247
BsmFI GGGAC 1 cut(s) 166
BsmI GAATGC 1 cut(s) 954
BsnI GGCC 3 cut(s) 105, 474, 542
Bsp1286I GDGCHC 3 cut(s) 96, 595, 1164
Bsp143I GATC 5 cut(s) 127, 163, 420, 654, 1037
Bsp19I CCATGG 1 cut(s) 475
BspACI CCGC 4 cut(s) 5, 77, 177, 552
BspANI GGCC 3 cut(s) 105, 474, 542
BspCNI CTCAG 3 cut(s) 496, 598, 1148
BspDI ATCGAT 1 cut(s) 657
BspFNI CGCG 2 cut(s) 77, 179
BspLI GGNNCC 4 cut(s) 396, 741, 846, 1102
BspMAI CTGCAG 2 cut(s) 1047, 1149
BspPI GGATC 2 cut(s) 171, 428
BspQI GCTCTTC 2 cut(s) 1022, 1049
BsrDI GCAATG 3 cut(s) 244, 255, 541
BsrFI RCCGGY 1 cut(s) 724
BsrI ACTGG 4 cut(s) 27, 191, 398, 971
BssAI RCCGGY 1 cut(s) 724
BssECI CCNNGG 3 cut(s) 99, 475, 839
BssMI GATC 5 cut(s) 127, 163, 420, 654, 1037
BssNI GRCGYC 1 cut(s) 155
BssSI CACGAG 2 cut(s) 618, 1016
BssT1I CCWWGG 3 cut(s) 99, 475, 839
Bst2BI CACGAG 2 cut(s) 618, 1016
Bst2UI CCWGG 1 cut(s) 767
Bst4CI ACNGT 6 cut(s) 391, 787, 899, 968, 1001, 1076
Bst6I CTCTTC 5 cut(s) 1017, 1022, 1049, 1173, 1179
BstACI GRCGYC 1 cut(s) 155
BstAPI GCANNNNNTGC 1 cut(s) 214
BstC8I GCNNGC 2 cut(s) 170, 174
BstDEI CTNAG 3 cut(s) 504, 606, 1135
BstDSI CCRYGG 1 cut(s) 475
BstF5I GGATG 2 cut(s) 762, 1140
BstFNI CGCG 2 cut(s) 77, 179
BstHHI GCGC 1 cut(s) 386
BstKTI GATC 5 cut(s) 130, 166, 423, 657, 1040
BstMAI GTCTC 2 cut(s) 248, 1247
BstMBI GATC 5 cut(s) 127, 163, 420, 654, 1037
BstMCI CGRYCG 1 cut(s) 657
BstMWI GCNNNNNNNGC 6 cut(s) 67, 214, 296, 383, 392, 623
BstNI CCWGG 1 cut(s) 767
BstNSI RCATGY 1 cut(s) 485
BstSCI CCNGG 5 cut(s) 89, 149, 765, 958, 1097
BstSFI CTRYAG 4 cut(s) 378, 636, 1043, 1145
BstUI CGCG 2 cut(s) 77, 179
BstV1I GCAGC 4 cut(s) 8, 48, 229, 232
BstX2I RGATCY 1 cut(s) 420
BstYI RGATCY 1 cut(s) 420
Bsu15I ATCGAT 1 cut(s) 657
BsuRI GGCC 3 cut(s) 105, 474, 542
BsuTUI ATCGAT 1 cut(s) 657
BtgI CCRYGG 1 cut(s) 475
BtsCI GGATG 2 cut(s) 762, 1140
BtsI GCAGTG 1 cut(s) 1040
BtsIMutI CAGTG 7 cut(s) 34, 317, 396, 792, 978, 1040, 1081
Cac8I GCNNGC 2 cut(s) 170, 174
CaiI CAGNNNCTG 1 cut(s) 211
CfoI GCGC 1 cut(s) 386
Cfr10I RCCGGY 1 cut(s) 724
Cfr13I GGNCC 4 cut(s) 103, 472, 1095, 1101
ClaI ATCGAT 1 cut(s) 657
CseI GACGC 1 cut(s) 163
Csp6I GTAC 4 cut(s) 13, 722, 806, 1132
CspAI ACCGGT 1 cut(s) 724
CviAII CATG 8 cut(s) 109, 115, 476, 482, 530, 566, 628, 904
CviQI GTAC 4 cut(s) 13, 722, 806, 1132
DdeI CTNAG 3 cut(s) 504, 606, 1135
DpnI GATC 5 cut(s) 129, 165, 422, 656, 1039
DpnII GATC 5 cut(s) 127, 163, 420, 654, 1037
DraIII CACNNNGTG 1 cut(s) 49
Eam1104I CTCTTC 5 cut(s) 1017, 1022, 1049, 1173, 1179
EarI CTCTTC 5 cut(s) 1017, 1022, 1049, 1173, 1179
EciI GGCGGA 1 cut(s) 567
Ecl136II GAGCTC 1 cut(s) 1162
Eco130I CCWWGG 3 cut(s) 99, 475, 839
Eco24I GRGCYC 2 cut(s) 96, 1164
Eco32I GATATC 1 cut(s) 661
Eco47I GGWCC 2 cut(s) 1095, 1101
Eco53kI GAGCTC 1 cut(s) 1162
Eco57I CTGAAG 1 cut(s) 1197
EcoICRI GAGCTC 1 cut(s) 1162
EcoRI GAATTC 1 cut(s) 1066
EcoRII CCWGG 1 cut(s) 765
EcoRV GATATC 1 cut(s) 661
EcoT14I CCWWGG 3 cut(s) 99, 475, 839
EcoT22I ATGCAT 1 cut(s) 531
EcoT38I GRGCYC 2 cut(s) 96, 1164
ErhI CCWWGG 3 cut(s) 99, 475, 839
FaeI CATG 8 cut(s) 112, 118, 479, 485, 533, 569, 631, 907
FaqI GGGAC 1 cut(s) 166
FatI CATG 8 cut(s) 108, 114, 475, 481, 529, 565, 627, 903
FauI CCCGC 1 cut(s) 70
FblI GTMKAC 1 cut(s) 990
Fnu4HI GCNGC 5 cut(s) 22, 62, 177, 243, 246
FokI GGATG 2 cut(s) 749, 1127
FriOI GRGCYC 2 cut(s) 96, 1164
Fsp4HI GCNGC 5 cut(s) 22, 62, 177, 243, 246
GlaI GCGC 1 cut(s) 385
GluI GCNGC 5 cut(s) 22, 62, 177, 243, 246
GsuI CTGGAG 1 cut(s) 381
HaeIII GGCC 3 cut(s) 105, 474, 542
HapII CCGG 7 cut(s) 90, 150, 543, 588, 725, 959, 1098
HgaI GACGC 1 cut(s) 163
HhaI GCGC 1 cut(s) 386
Hin1I GRCGYC 1 cut(s) 155
Hin1II CATG 8 cut(s) 112, 118, 479, 485, 533, 569, 631, 907
Hin6I GCGC 1 cut(s) 384
HinP1I GCGC 1 cut(s) 384
HincII GTYRAC 3 cut(s) 561, 783, 991
HindII GTYRAC 3 cut(s) 561, 783, 991
HindIII AAGCTT 2 cut(s) 288, 671
HinfI GANTC 8 cut(s) 33, 322, 600, 631, 691, 759, 835, 1274
HpaI GTTAAC 1 cut(s) 783
HpaII CCGG 7 cut(s) 90, 150, 543, 588, 725, 959, 1098
HphI GGTGA 5 cut(s) 88, 974, 994, 1013, 1169
Hpy166II GTNNAC 4 cut(s) 561, 783, 790, 991
Hpy188I TCNGA 3 cut(s) 607, 1065, 1138
Hpy188III TCNNGA 7 cut(s) 131, 272, 363, 620, 848, 1016, 1104
Hpy8I GTNNAC 4 cut(s) 561, 783, 790, 991
Hpy99I CGWCG 1 cut(s) 128
HpyAV CCTTC 2 cut(s) 154, 915
HpyCH4III ACNGT 6 cut(s) 391, 787, 899, 968, 1001, 1076
HpyF10VI GCNNNNNNNGC 6 cut(s) 67, 214, 296, 383, 392, 623
HpyF3I CTNAG 3 cut(s) 504, 606, 1135
Hsp92I GRCGYC 1 cut(s) 155
Hsp92II CATG 8 cut(s) 112, 118, 479, 485, 533, 569, 631, 907
HspAI GCGC 1 cut(s) 384
KspAI GTTAAC 1 cut(s) 783
Kzo9I GATC 5 cut(s) 127, 163, 420, 654, 1037
LguI GCTCTTC 2 cut(s) 1022, 1049
LmnI GCTCC 5 cut(s) 400, 590, 739, 940, 1167
Lsp1109I GCAGC 4 cut(s) 8, 48, 229, 232
LweI GCATC 3 cut(s) 217, 613, 1206
MaeIII GTNAC 5 cut(s) 313, 820, 893, 899, 962
MalI GATC 5 cut(s) 129, 165, 422, 656, 1039
MboI GATC 5 cut(s) 127, 163, 420, 654, 1037
MflI RGATCY 1 cut(s) 420
MhlI GDGCHC 3 cut(s) 96, 595, 1164
MluCI AATT 5 cut(s) 264, 682, 775, 1066, 1084
MlyI GAGTC 4 cut(s) 594, 625, 753, 1268
Mph1103I ATGCAT 1 cut(s) 531
MseI TTAA 1 cut(s) 782
MslI CAYNNNNRTG 5 cut(s) 113, 311, 480, 534, 1205
MspI CCGG 7 cut(s) 90, 150, 543, 588, 725, 959, 1098
MspR9I CCNGG 5 cut(s) 91, 151, 767, 960, 1099
Mva1269I GAATGC 1 cut(s) 954
MvaI CCWGG 1 cut(s) 767
MvnI CGCG 2 cut(s) 77, 179
MwoI GCNNNNNNNGC 6 cut(s) 67, 214, 296, 383, 392, 623
NciI CCSGG 4 cut(s) 91, 151, 960, 1099
NcoI CCATGG 1 cut(s) 475
NdeII GATC 5 cut(s) 127, 163, 420, 654, 1037
NlaIII CATG 8 cut(s) 112, 118, 479, 485, 533, 569, 631, 907
NlaIV GGNNCC 4 cut(s) 396, 741, 846, 1102
NmuCI GTSAC 5 cut(s) 313, 820, 893, 899, 962
NsiI ATGCAT 1 cut(s) 531
NspI RCATGY 1 cut(s) 485
PciI ACATGT 1 cut(s) 481
PciSI GCTCTTC 2 cut(s) 1022, 1049
PcsI WCGNNNNNNNCGW 1 cut(s) 129
PctI GAATGC 1 cut(s) 954
PfeI GAWTC 4 cut(s) 33, 322, 691, 835
PflFI GACNNNGTC 1 cut(s) 1099
PfoI TCCNGGA 1 cut(s) 149
PinAI ACCGGT 1 cut(s) 724
PkrI GCNGC 5 cut(s) 23, 63, 178, 244, 247
Ple19I CGATCG 1 cut(s) 657
PleI GAGTC 4 cut(s) 594, 625, 753, 1268
PpsI GAGTC 4 cut(s) 594, 625, 753, 1268
PscI ACATGT 1 cut(s) 481
Psp124BI GAGCTC 1 cut(s) 1164
Psp6I CCWGG 1 cut(s) 765
PspGI CCWGG 1 cut(s) 765
PspN4I GGNNCC 4 cut(s) 396, 741, 846, 1102
PspPI GGNCC 4 cut(s) 103, 472, 1095, 1101
PstI CTGCAG 2 cut(s) 1047, 1149
PstNI CAGNNNCTG 1 cut(s) 211
PsuI RGATCY 1 cut(s) 420
PsyI GACNNNGTC 1 cut(s) 1099
PvuI CGATCG 1 cut(s) 657
RsaI GTAC 4 cut(s) 14, 723, 807, 1133
RsaNI GTAC 4 cut(s) 13, 722, 806, 1132
RseI CAYNNNNRTG 5 cut(s) 113, 311, 480, 534, 1205
SacI GAGCTC 1 cut(s) 1164
SalI GTCGAC 1 cut(s) 989
SapI GCTCTTC 2 cut(s) 1022, 1049
SaqAI TTAA 1 cut(s) 782
SatI GCNGC 5 cut(s) 22, 62, 177, 243, 246
Sau3AI GATC 5 cut(s) 127, 163, 420, 654, 1037
Sau96I GGNCC 4 cut(s) 103, 472, 1095, 1101
SchI GAGTC 4 cut(s) 594, 625, 753, 1268
ScrFI CCNGG 5 cut(s) 91, 151, 767, 960, 1099
SduI GDGCHC 3 cut(s) 96, 595, 1164
SfaNI GCATC 3 cut(s) 217, 613, 1206
SfcI CTRYAG 4 cut(s) 378, 636, 1043, 1145
SinI GGWCC 2 cut(s) 1095, 1101
SmiMI CAYNNNNRTG 5 cut(s) 113, 311, 480, 534, 1205
Sse9I AATT 5 cut(s) 264, 682, 775, 1066, 1084
SsiI CCGC 4 cut(s) 5, 77, 177, 552
SspI AATATT 2 cut(s) 699, 751
SstI GAGCTC 1 cut(s) 1164
StyD4I CCNGG 5 cut(s) 89, 149, 765, 958, 1097
StyI CCWWGG 3 cut(s) 99, 475, 839
TaaI ACNGT 6 cut(s) 391, 787, 899, 968, 1001, 1076
TaqI TCGA 6 cut(s) 126, 132, 657, 990, 1221, 1269
TasI AATT 5 cut(s) 264, 682, 775, 1066, 1084
TatI WGTACW 1 cut(s) 1131
TauI GCSGC 1 cut(s) 179
TfiI GAWTC 4 cut(s) 33, 322, 691, 835
Tru1I TTAA 1 cut(s) 782
Tru9I TTAA 1 cut(s) 782
TscAI CASTG 7 cut(s) 34, 324, 396, 792, 978, 1047, 1081
TseFI GTSAC 5 cut(s) 313, 820, 893, 899, 962
TseI GCWGC 4 cut(s) 21, 61, 242, 245
Tsp45I GTSAC 5 cut(s) 313, 820, 893, 899, 962
TspDTI ATGAA 4 cut(s) 28, 585, 704, 1077
TspGWI ACGGA 2 cut(s) 395, 953
TspRI CASTG 7 cut(s) 34, 324, 396, 792, 978, 1047, 1081
Tth111I GACNNNGTC 1 cut(s) 1099
VpaK11BI GGWCC 2 cut(s) 1095, 1101
XapI RAATTY 3 cut(s) 682, 775, 1066
XceI RCATGY 1 cut(s) 485
XmiI GTMKAC 1 cut(s) 990
Zsp2I ATGCAT 1 cut(s) 531
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.