Basic Information

Type: gene

Biological Identity

Species

malus_domestica

Chromosome

Chr17

Orthogroup ID

OG0005226

Physical Location & Seq

Genomic Coordinates Reverse (-)

33157827 .. 33162634

Gene Structure 4808 bp

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UTR

Exon/CDS

Intron

Transcript / Protein ID

MD17G1270700.v1.1.491

Sequence Viewer

CDS Protein Promoter (2k)

Length: 1239 bp

ATGGCTTTCCAGAAGATCAAGGTTGCCAACCCCATCGTCGAGATGGACGGAGACGAAATGACAAGAGTTTTCTGGAAATCCATTAAAGACAAGCTTATTTTACCATTTGTGGAATTGGACATCAAGTACTTTGACCTTGGCCTTCCTCATCGTGATGCCACTGATGACAAGGTTACTGTTGAAAGTGCTGAGGCTACTCTCAAGTATAATGTAGCAATCAAGTGTGCGACTATTACTCCAGATGAAGCTCGTATGAAGGAGTTTAGCTTGAAGAGTATGTGGAGGAGTCCCAACGGGACCATTAGGAATATTTTGAATGGTACTGTTTTCAGAGAACCAATTCTTTGCAAAAACATCCCTCGCCTTATCCCAGGCTGGACAAAGCCAATATGCATTGGAAGACATGCTTTTGGTGATCAGTATCGAGCAACTGATGCAGTCATTAAGGGACCGGGGAAACTGAAATTGGTGTTTGTGCCAGAAGGAAAGGATGAGAAGACAGAGCTAGACGTGTACGACTTTACAGGGGAGGGGGGAGTAGCATTGGCCATGTACAACACCGATGAGTCCATCCGTGCTTTTGCAGAGGCTTCCATGACCACTGCTTATGAGAAAAAGTGGCCTCTTTATCTTAGCACAAAAAATACTATTCTGAAGAAGTATGATGGAAGATTCAAGGACATATTTCAAGAAGTTTATGAAGCTAACTGGAAATCAAAGTTTGATGCTGCTGGCATATGGTATGAGCATCGTCTCATTGATGATATGGTGGCTTATGCACTTAAAAGTGATGGTGCGTATGTTTGGGCATGCAAGAATTATGATGGAGATGTGCAAAGTGATATGTTAGCTCAAGGGTTTGGATCTCTTGGATTGATGACATCCGTACTGGTGTGCCCAGATGGAAAGACTATTGAAGCTGAAGCTGCACACGGTACAGTTACTCGGCATTACAGGGTTCACCAGAAGGGAGGTGAAACAAGTACAAACAGCATTGCTTCCATCTTTGCTTGGACAAGAGGGCTTGCACACAGGGCTAAGTTGGATGACAATGCAAGACTTTTGGAATTCACTCAAAAACTCGAAGAAGCTTGTATTGGAACTGTGGAATCAGGGAAAATGACCAAGGATCTTGCACTAATTCTTCACGGATCCAAGCTGGCTAGGAACCACTACTTGAACACTGAAGAGTTCATTGATGCTGTGGCCGAGGAACTGAAAGCTAAGCTTGCTTGCTAG

Functional Annotation

Gene Ontology

Molecular Function
Biological Process
Cellular Component

GO:0003674 GO:0003824 GO:0004448 GO:0004450 GO:0005488 GO:0005507 GO:0005575 GO:0005576 GO:0005622 GO:0005623 GO:0005737 GO:0005829 GO:0005886 GO:0005911 GO:0006082 GO:0006102 GO:0006139 GO:0006725 GO:0006732 GO:0006733 GO:0006739 GO:0006753 GO:0006793 GO:0006796 GO:0006807 GO:0006950 GO:0006952 GO:0006970 GO:0008150 GO:0008152 GO:0009117 GO:0009506 GO:0009507 GO:0009532 GO:0009536 GO:0009570 GO:0009605 GO:0009607 GO:0009617 GO:0009628 GO:0009651 GO:0009987 GO:0010035 GO:0010038 GO:0010043 GO:0016020 GO:0016491 GO:0016614 GO:0016616 GO:0019362 GO:0019637 GO:0019752 GO:0030054 GO:0034641 GO:0042221 GO:0042742 GO:0043167 GO:0043169 GO:0043207 GO:0043226 GO:0043227 GO:0043229 GO:0043231 GO:0043436 GO:0044237 GO:0044238 GO:0044281 GO:0044422 GO:0044424 GO:0044434 GO:0044435 GO:0044444 GO:0044446 GO:0044464 GO:0046483 GO:0046496 GO:0046686 GO:0046872 GO:0046914 GO:0048046 GO:0050896 GO:0051186 GO:0051704 GO:0051707 GO:0055044 GO:0055086 GO:0055114 GO:0071704 GO:0071944 GO:0072350 GO:0072524 GO:0098542 GO:1901360 GO:1901564

KEGG Pathways

Metabolic & Signaling

ko00020 ko00480 ko00720 ko01100 ko01110 ko01120 ko01130 ko01200 ko01210 ko01230 ko04146 map00020 map00480 map00720 map01100 map01110 map01120 map01130 map01200 map01210 map01230 map04146

Pfam Domains

Protein Families

Iso_dh

Protein Analysis

413

Amino Acids

46.27

Weight (kDa)

6.35

Isoelectric Point (pI)

22.81

Instability Index

Protein Domains (Pfam)

Domain Name	Pfam ID	Position	E-value	Description
Iso_dh	PF00180	7 - 402	5.2e-82	Isocitrate/isopropylmalate dehydrogenase

Hydrophobicity Profile (Kyte-Doolittle)

AI Structure Prediction Report

Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter

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Align Labels (Cladogram)

Image

Tree File

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Publication-ready

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Orthologous Genes (Group: OG0005226)

Species	Orthologous Gene IDs
arabidopsis_thaliana	AT1G65930
fragaria_vesca	FvH4_1g27490 FvH4_1g27490 FvH4_1g30530 FvH4_1g30530
malus_domestica	MD09G1276900.v1.1 MD09G1277300.v1.1 MD17G1270700.v1.1
prunus_persica	Prupe.3G015500_v2.0.a1 Prupe.3G015500_v2.0.a1 Prupe.3G015500_v2.0.a1 Prupe.3G015500_v2.0.a1
pyrus_communis	pycom09g18670 pycom17g26910
rosa_chinensis	RchiOBHm_Chr3g0489041 RchiOBHm_Chr3g0489051
rosa_laevigata	RLG00000022897 RLG00000022898
rosa_multiflora	Rmu_sc0002227.1_g000003 Rmu_sc0011911.1_g000008
rosa_roxburghii	Rroxscaffold_6G00393730
rosa_rugosa	Rorug03G0242800 Rorug03G0242900 Rorug03G0242900
rosa_samantha	Rh3AG291100 Rh3BG327800 Rh3DG324200
rosa_wichuraiana	Rw3G025760 Rw3G025770

Restriction Enzyme Sites

1 / 10

Enzyme	Recognition Site	Cut Count	Positions (bp)
AclWI	GGATC	4 cut(s)	871, 1137, 1146, 1159
AcoI	YGGCCR	2 cut(s)	546, 1206
AcsI	RAATTY	1 cut(s)	1067
AcuI	CTGAAG	3 cut(s)	674, 942, 1206
AfaI	GTAC	7 cut(s)	128, 322, 515, 554, 888, 937, 985
AflIII	ACRYGT	1 cut(s)	510
AgsI	TTSAA	7 cut(s)	182, 271, 316, 676, 689, 917, 1180
AjiI	CACGTC	1 cut(s)	511
AjnI	CCWGG	1 cut(s)	370
AjuI	GAANNNNNNNTTGG	4 cut(s)	449, 481, 1080, 1112
Alw26I	GTCTC	2 cut(s)	45, 758
AlwI	GGATC	4 cut(s)	871, 1137, 1146, 1159
AoxI	GGCC	4 cut(s)	139, 546, 620, 1206
ApeKI	GCWGC	2 cut(s)	728, 926
ApoI	RAATTY	1 cut(s)	1067
Asp700I	GAANNNNTTC	1 cut(s)	339
AspS9I	GGNCC	2 cut(s)	297, 449
AsuC2I	CCSGG	1 cut(s)	453
AsuHPI	GGTGA	3 cut(s)	425, 953, 986
AvaII	GGWCC	2 cut(s)	297, 449
BaeGI	GKGCMC	1 cut(s)	899
BalI	TGGCCA	1 cut(s)	548
BamHI	GGATCC	1 cut(s)	1151
BbsI	GAAGAC	2 cut(s)	406, 503
BbvCI	CCTCAGC	1 cut(s)	189
BbvI	GCAGC	2 cut(s)	715, 913
BccI	CCATC	8 cut(s)	37, 41, 578, 659, 785, 818, 896, 1010
BciT130I	CCWGG	1 cut(s)	372
BclI	TGATCA	1 cut(s)	415
BcnI	CCSGG	1 cut(s)	453
BcoDI	GTCTC	2 cut(s)	45, 758
BfaI	CTAG	3 cut(s)	506, 1164, 1237
BisI	GCNGC	2 cut(s)	729, 927
BlpI	GCTNAGC	1 cut(s)	1224
BlsI	GCNGC	2 cut(s)	730, 928
BmcAI	AGTACT	1 cut(s)	128
Bme1390I	CCNGG	2 cut(s)	372, 453
Bme18I	GGWCC	2 cut(s)	297, 449
BmgBI	CACGTC	1 cut(s)	511
BmgT120I	GGNCC	2 cut(s)	297, 449
BmiI	GGNNCC	4 cut(s)	298, 450, 1153, 1169
BmrFI	CCNGG	2 cut(s)	372, 453
BmsI	GCATC	5 cut(s)	145, 424, 715, 757, 1189
BpiI	GAAGAC	2 cut(s)	406, 503
BpmI	CTGGAG	1 cut(s)	222
Bpu10I	CCTNAGC	1 cut(s)	189
Bpu1102I	GCTNAGC	1 cut(s)	1224
BpuEI	CTTGAG	2 cut(s)	185, 837
BpuMI	CCSGG	1 cut(s)	453
BsaBI	GATNNNNATC	1 cut(s)	420
BsaJI	CCNNGG	5 cut(s)	136, 370, 452, 1125, 1209
BsaXI	ACNNNNNCTCC	2 cut(s)	220, 250
Bse1I	ACTGG	2 cut(s)	713, 894
Bse3DI	GCAATG	1 cut(s)	993
Bse8I	GATNNNNATC	1 cut(s)	420
BseBI	CCWGG	1 cut(s)	372
BseDI	CCNNGG	5 cut(s)	136, 370, 452, 1125, 1209
BseGI	GGATG	5 cut(s)	354, 496, 570, 881, 1051
BseJI	GATNNNNATC	1 cut(s)	420
BseMI	GCAATG	1 cut(s)	993
BseMII	CTCAG	1 cut(s)	180
BseNI	ACTGG	2 cut(s)	713, 894
BseRI	GAGGAG	1 cut(s)	298
BseSI	GKGCMC	1 cut(s)	899
BseXI	GCAGC	2 cut(s)	715, 913
BsgI	GTGCAG	1 cut(s)	912
BshFI	GGCC	4 cut(s)	141, 548, 622, 1208
BsiSI	CCGG	1 cut(s)	452
BslFI	GGGAC	3 cut(s)	273, 310, 462
BsmAI	GTCTC	2 cut(s)	45, 758
BsmBI	CGTCTC	2 cut(s)	45, 758
BsmFI	GGGAC	3 cut(s)	273, 310, 462
BsnI	GGCC	4 cut(s)	141, 548, 622, 1208
Bsp1286I	GDGCHC	1 cut(s)	899
Bsp1407I	TGTACA	1 cut(s)	552
Bsp143I	GATC	5 cut(s)	15, 415, 863, 1129, 1151
Bsp1720I	GCTNAGC	1 cut(s)	1224
BspANI	GGCC	4 cut(s)	141, 548, 622, 1208
BspCNI	CTCAG	1 cut(s)	181
BspLI	GGNNCC	4 cut(s)	298, 450, 1153, 1169
BspPI	GGATC	4 cut(s)	871, 1137, 1146, 1159
BsrDI	GCAATG	1 cut(s)	993
BsrGI	TGTACA	1 cut(s)	552
BsrI	ACTGG	2 cut(s)	713, 894
BssECI	CCNNGG	5 cut(s)	136, 370, 452, 1125, 1209
BssMI	GATC	5 cut(s)	15, 415, 863, 1129, 1151
BssT1I	CCWWGG	2 cut(s)	136, 1125
Bst2UI	CCWGG	1 cut(s)	372
Bst4CI	ACNGT	5 cut(s)	178, 325, 935, 940, 1105
Bst6I	CTCTTC	2 cut(s)	266, 1182
BstAPI	GCANNNNNTGC	1 cut(s)	434
BstAUI	TGTACA	1 cut(s)	552
BstC8I	GCNNGC	6 cut(s)	733, 811, 1026, 1161, 1230, 1234
BstDEI	CTNAG	4 cut(s)	189, 632, 1038, 1224
BstF5I	GGATG	5 cut(s)	354, 496, 570, 881, 1051
BstKTI	GATC	5 cut(s)	18, 418, 866, 1132, 1154
BstMAI	GTCTC	2 cut(s)	45, 758
BstMBI	GATC	5 cut(s)	15, 415, 863, 1129, 1151
BstMWI	GCNNNNNNNGC	4 cut(s)	434, 926, 1034, 1229
BstNI	CCWGG	1 cut(s)	372
BstNSI	RCATGY	2 cut(s)	407, 813
BstSCI	CCNGG	2 cut(s)	370, 451
BstSLI	GKGCMC	1 cut(s)	899
BstV1I	GCAGC	2 cut(s)	715, 913
BstV2I	GAAGAC	2 cut(s)	406, 503
BstX2I	RGATCY	3 cut(s)	863, 1129, 1151
BstYI	RGATCY	3 cut(s)	863, 1129, 1151
BsuRI	GGCC	4 cut(s)	141, 548, 622, 1208
BtrI	CACGTC	1 cut(s)	511
BtsCI	GGATG	5 cut(s)	354, 496, 570, 881, 1051
BtsI	GCAGTG	1 cut(s)	600
BtsIMutI	CAGTG	3 cut(s)	159, 600, 1182
Cac8I	GCNNGC	6 cut(s)	733, 811, 1026, 1161, 1230, 1234
Cfr13I	GGNCC	2 cut(s)	297, 449
Csp6I	GTAC	7 cut(s)	127, 321, 514, 553, 887, 936, 984
CviAII	CATG	4 cut(s)	404, 550, 595, 810
CviQI	GTAC	7 cut(s)	127, 321, 514, 553, 887, 936, 984
DdeI	CTNAG	4 cut(s)	189, 632, 1038, 1224
DpnI	GATC	5 cut(s)	17, 417, 865, 1131, 1153
DpnII	GATC	5 cut(s)	15, 415, 863, 1129, 1151
EaeI	YGGCCR	2 cut(s)	546, 1206
Eam1104I	CTCTTC	2 cut(s)	266, 1182
EarI	CTCTTC	2 cut(s)	266, 1182
Eco130I	CCWWGG	2 cut(s)	136, 1125
Eco47I	GGWCC	2 cut(s)	297, 449
Eco57I	CTGAAG	3 cut(s)	674, 942, 1206
EcoRI	GAATTC	1 cut(s)	1067
EcoRII	CCWGG	1 cut(s)	370
EcoT14I	CCWWGG	2 cut(s)	136, 1125
EcoT22I	ATGCAT	1 cut(s)	395
ErhI	CCWWGG	2 cut(s)	136, 1125
Esp3I	CGTCTC	2 cut(s)	45, 758
FaeI	CATG	4 cut(s)	407, 553, 598, 813
FalI	AAGNNNNNCTT	5 cut(s)	78, 110, 391, 423, 1212
FaqI	GGGAC	3 cut(s)	273, 310, 462
FatI	CATG	4 cut(s)	403, 549, 594, 809
FauNDI	CATATG	1 cut(s)	737
FbaI	TGATCA	1 cut(s)	415
Fnu4HI	GCNGC	2 cut(s)	729, 927
FokI	GGATG	5 cut(s)	341, 503, 557, 868, 1058
Fsp4HI	GCNGC	2 cut(s)	729, 927
FspBI	CTAG	3 cut(s)	506, 1164, 1237
GluI	GCNGC	2 cut(s)	729, 927
GsuI	CTGGAG	1 cut(s)	222
HaeIII	GGCC	4 cut(s)	141, 548, 622, 1208
HapII	CCGG	1 cut(s)	452
Hin1II	CATG	4 cut(s)	407, 553, 598, 813
HindIII	AAGCTT	3 cut(s)	92, 1089, 1226
HinfI	GANTC	4 cut(s)	286, 566, 672, 1109
HpaII	CCGG	1 cut(s)	452
HphI	GGTGA	3 cut(s)	425, 953, 986
Hpy166II	GTNNAC	2 cut(s)	514, 961
Hpy188I	TCNGA	2 cut(s)	332, 654
Hpy188III	TCNNGA	6 cut(s)	10, 40, 73, 152, 239, 689
Hpy8I	GTNNAC	2 cut(s)	514, 961
Hpy99I	CGWCG	1 cut(s)	41
HpyAV	CCTTC	4 cut(s)	152, 250, 476, 961
HpyCH4III	ACNGT	5 cut(s)	178, 325, 935, 940, 1105
HpyCH4IV	ACGT	1 cut(s)	510
HpyF10VI	GCNNNNNNNGC	4 cut(s)	434, 926, 1034, 1229
HpyF3I	CTNAG	4 cut(s)	189, 632, 1038, 1224
HpySE526I	ACGT	1 cut(s)	510
Hsp92II	CATG	4 cut(s)	407, 553, 598, 813
Ksp22I	TGATCA	1 cut(s)	415
Kzo9I	GATC	5 cut(s)	15, 415, 863, 1129, 1151
Lsp1109I	GCAGC	2 cut(s)	715, 913
LweI	GCATC	5 cut(s)	145, 424, 715, 757, 1189
MaeI	CTAG	3 cut(s)	506, 1164, 1237
MaeII	ACGT	1 cut(s)	510
MaeIII	GTNAC	2 cut(s)	172, 940
MalI	GATC	5 cut(s)	17, 417, 865, 1131, 1153
MboI	GATC	5 cut(s)	15, 415, 863, 1129, 1151
MboII	GAAGA	9 cut(s)	25, 283, 411, 508, 667, 681, 1097, 1136, 1199
MflI	RGATCY	3 cut(s)	863, 1129, 1151
MhlI	GDGCHC	1 cut(s)	899
MlsI	TGGCCA	1 cut(s)	548
MluCI	AATT	6 cut(s)	113, 339, 464, 817, 1067, 1140
MluNI	TGGCCA	1 cut(s)	548
MlyI	GAGTC	2 cut(s)	295, 575
MmeI	TCCRAC	1 cut(s)	1023
Mox20I	TGGCCA	1 cut(s)	548
Mph1103I	ATGCAT	1 cut(s)	395
MroXI	GAANNNNTTC	1 cut(s)	339
MscI	TGGCCA	1 cut(s)	548
MseI	TTAA	3 cut(s)	84, 444, 783
MslI	CAYNNNNRTG	1 cut(s)	153
Msp20I	TGGCCA	1 cut(s)	548
MspI	CCGG	1 cut(s)	452
MspR9I	CCNGG	2 cut(s)	372, 453
MvaI	CCWGG	1 cut(s)	372
MwoI	GCNNNNNNNGC	4 cut(s)	434, 926, 1034, 1229
NciI	CCSGG	1 cut(s)	453
NdeI	CATATG	1 cut(s)	737
NdeII	GATC	5 cut(s)	15, 415, 863, 1129, 1151
NlaIII	CATG	4 cut(s)	407, 553, 598, 813
NlaIV	GGNNCC	4 cut(s)	298, 450, 1153, 1169
NmeAIII	GCCGAG	2 cut(s)	925, 1234
NsiI	ATGCAT	1 cut(s)	395
NspI	RCATGY	2 cut(s)	407, 813
PaeI	GCATGC	1 cut(s)	813
PdmI	GAANNNNTTC	1 cut(s)	339
PfeI	GAWTC	2 cut(s)	672, 1109
PkrI	GCNGC	2 cut(s)	730, 928
PleI	GAGTC	2 cut(s)	294, 574
PpsI	GAGTC	2 cut(s)	294, 574
Psp6I	CCWGG	1 cut(s)	370
PspGI	CCWGG	1 cut(s)	370
PspN4I	GGNNCC	4 cut(s)	298, 450, 1153, 1169
PspPI	GGNCC	2 cut(s)	297, 449
PsuI	RGATCY	3 cut(s)	863, 1129, 1151
RsaI	GTAC	7 cut(s)	128, 322, 515, 554, 888, 937, 985
RsaNI	GTAC	7 cut(s)	127, 321, 514, 553, 887, 936, 984
RseI	CAYNNNNRTG	1 cut(s)	153
SaqAI	TTAA	3 cut(s)	84, 444, 783
SatI	GCNGC	2 cut(s)	729, 927
Sau3AI	GATC	5 cut(s)	15, 415, 863, 1129, 1151
Sau96I	GGNCC	2 cut(s)	297, 449
ScaI	AGTACT	1 cut(s)	128
SchI	GAGTC	2 cut(s)	295, 575
ScrFI	CCNGG	2 cut(s)	372, 453
SduI	GDGCHC	1 cut(s)	899
SfaNI	GCATC	5 cut(s)	145, 424, 715, 757, 1189
SinI	GGWCC	2 cut(s)	297, 449
SmiMI	CAYNNNNRTG	1 cut(s)	153
SmlI	CTYRAG	2 cut(s)	200, 852
SmoI	CTYRAG	2 cut(s)	200, 852
SphI	GCATGC	1 cut(s)	813
Sse9I	AATT	6 cut(s)	113, 339, 464, 817, 1067, 1140
SspI	AATATT	1 cut(s)	310
SspMI	CTAG	3 cut(s)	506, 1164, 1237
StyD4I	CCNGG	2 cut(s)	370, 451
StyI	CCWWGG	2 cut(s)	136, 1125
TaaI	ACNGT	5 cut(s)	178, 325, 935, 940, 1105
TaiI	ACGT	1 cut(s)	513
TaqI	TCGA	3 cut(s)	39, 424, 1083
TasI	AATT	6 cut(s)	113, 339, 464, 817, 1067, 1140
TatI	WGTACW	3 cut(s)	126, 552, 983
TfiI	GAWTC	2 cut(s)	672, 1109
Tru1I	TTAA	3 cut(s)	84, 444, 783
Tru9I	TTAA	3 cut(s)	84, 444, 783
TscAI	CASTG	3 cut(s)	166, 607, 1189
TseI	GCWGC	2 cut(s)	728, 926
TspDTI	ATGAA	4 cut(s)	258, 269, 714, 1183
TspGWI	ACGGA	4 cut(s)	63, 563, 874, 1164
TspRI	CASTG	3 cut(s)	166, 607, 1189
VpaK11BI	GGWCC	2 cut(s)	297, 449
XapI	RAATTY	1 cut(s)	1067
XceI	RCATGY	2 cut(s)	407, 813
XcmI	CCANNNNNNNNNTGG	1 cut(s)	40
XmnI	GAANNNNTTC	1 cut(s)	339
XspI	CTAG	3 cut(s)	506, 1164, 1237
ZrmI	AGTACT	1 cut(s)	128
Zsp2I	ATGCAT	1 cut(s)	395

Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.