The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins. Some of these proteins have been shown both in vivo and in vitro to have ubiquitin E3 ligase activity.
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| Species | Orthologous Gene IDs |
|---|---|
| arabidopsis_thaliana | AT2G45530 |
| fragaria_vesca | FvH4_5g10340 |
| malus_domestica | MD06G1124900.v1.1 |
| prunus_persica | Prupe.5G135500_v2.0.a1 Prupe.5G135500_v2.0.a1 Prupe.5G135500_v2.0.a1 Prupe.5G135500_v2.0.a1 Prupe.5G135500_v2.0.a1 Prupe.5G135500_v2.0.a1 Prupe.5G135500_v2.0.a1 Prupe.5G135500_v2.0.a1 Prupe.5G135500_v2.0.a1 Prupe.5G135500_v2.0.a1 Prupe.5G135500_v2.0.a1 Prupe.5G135500_v2.0.a1 Prupe.5G135500_v2.0.a1 Prupe.5G135500_v2.0.a1 Prupe.5G135500_v2.0.a1 Prupe.5G135500_v2.0.a1 Prupe.5G135500_v2.0.a1 |
| pyrus_communis | pycom06g11550 pycom14g11700 |
| rosa_chinensis | RchiOBHm_Chr7g0187881 |
| rosa_multiflora | Rmu_sc0022114.1_g000002 |
| rosa_roxburghii | Rroxscaffold_3G00266980 |
| rosa_rugosa | Rorug06G0485000 |
| rosa_samantha | Rh7AG090200 Rh7BG091800 Rh7CG090900 |
| rosa_wichuraiana | Rw7G007790 |
| Enzyme | Recognition Site | Cut Count | Positions (bp) |
|---|---|---|---|
| Acc65I | GGTACC | 1 cut(s) | 232 |
| AccB1I | GGYRCC | 2 cut(s) | 148, 232 |
| AccII | CGCG | 1 cut(s) | 192 |
| AciI | CCGC | 3 cut(s) | 102, 152, 155 |
| AclWI | GGATC | 1 cut(s) | 409 |
| AcoI | YGGCCR | 1 cut(s) | 213 |
| AcsI | RAATTY | 1 cut(s) | 692 |
| AcyI | GRCGYC | 1 cut(s) | 185 |
| AfaI | GTAC | 1 cut(s) | 234 |
| AfiI | CCNNNNNNNGG | 2 cut(s) | 248, 470 |
| AgsI | TTSAA | 1 cut(s) | 561 |
| AjiI | CACGTC | 1 cut(s) | 589 |
| AjuI | GAANNNNNNNTTGG | 2 cut(s) | 119, 151 |
| AleI | CACNNNNGTG | 1 cut(s) | 743 |
| AluBI | AGCT | 5 cut(s) | 107, 117, 273, 434, 477 |
| AluI | AGCT | 5 cut(s) | 107, 117, 273, 434, 477 |
| Alw21I | GWGCWC | 1 cut(s) | 27 |
| Alw26I | GTCTC | 4 cut(s) | 192, 516, 619, 673 |
| AlwI | GGATC | 1 cut(s) | 409 |
| AoxI | GGCC | 1 cut(s) | 213 |
| ApeKI | GCWGC | 2 cut(s) | 88, 434 |
| ApoI | RAATTY | 1 cut(s) | 692 |
| Asp718I | GGTACC | 1 cut(s) | 232 |
| AsuHPI | GGTGA | 3 cut(s) | 29, 152, 263 |
| AsuII | TTCGAA | 1 cut(s) | 391 |
| BanI | GGYRCC | 2 cut(s) | 148, 232 |
| Bbv12I | GWGCWC | 1 cut(s) | 27 |
| BbvI | GCAGC | 2 cut(s) | 100, 421 |
| BccI | CCATC | 1 cut(s) | 768 |
| BceAI | ACGGC | 1 cut(s) | 228 |
| BcoDI | GTCTC | 4 cut(s) | 192, 516, 619, 673 |
| BfaI | CTAG | 1 cut(s) | 114 |
| BisI | GCNGC | 4 cut(s) | 89, 152, 155, 435 |
| BlpI | GCTNAGC | 1 cut(s) | 108 |
| BlsI | GCNGC | 4 cut(s) | 90, 153, 156, 436 |
| BmgBI | CACGTC | 1 cut(s) | 589 |
| BmiI | GGNNCC | 2 cut(s) | 150, 234 |
| BmrI | ACTGGG | 1 cut(s) | 490 |
| BmuI | ACTGGG | 1 cut(s) | 490 |
| BplI | GAGNNNNNCTC | 2 cut(s) | 101, 133 |
| BpmI | CTGGAG | 1 cut(s) | 508 |
| Bpu1102I | GCTNAGC | 1 cut(s) | 108 |
| Bpu14I | TTCGAA | 1 cut(s) | 391 |
| Bsa29I | ATCGAT | 1 cut(s) | 44 |
| BsaHI | GRCGYC | 1 cut(s) | 185 |
| BsaJI | CCNNGG | 4 cut(s) | 210, 328, 424, 607 |
| Bsc4I | CCNNNNNNNGG | 2 cut(s) | 248, 470 |
| Bse1I | ACTGG | 2 cut(s) | 485, 703 |
| BseCI | ATCGAT | 1 cut(s) | 44 |
| BseDI | CCNNGG | 4 cut(s) | 210, 328, 424, 607 |
| BseGI | GGATG | 3 cut(s) | 184, 338, 760 |
| BseLI | CCNNNNNNNGG | 2 cut(s) | 248, 470 |
| BseMII | CTCAG | 3 cut(s) | 99, 482, 668 |
| BseNI | ACTGG | 2 cut(s) | 485, 703 |
| BseRI | GAGGAG | 2 cut(s) | 64, 730 |
| BseXI | GCAGC | 2 cut(s) | 100, 421 |
| BseYI | CCCAGC | 1 cut(s) | 459 |
| BsgI | GTGCAG | 3 cut(s) | 603, 657, 746 |
| Bsh1236I | CGCG | 1 cut(s) | 192 |
| BshFI | GGCC | 1 cut(s) | 215 |
| BshNI | GGYRCC | 2 cut(s) | 148, 232 |
| BshVI | ATCGAT | 1 cut(s) | 44 |
| BsiHKAI | GWGCWC | 1 cut(s) | 27 |
| BslI | CCNNNNNNNGG | 2 cut(s) | 248, 470 |
| BsmAI | GTCTC | 4 cut(s) | 192, 516, 619, 673 |
| BsmBI | CGTCTC | 1 cut(s) | 192 |
| BsnI | GGCC | 1 cut(s) | 215 |
| Bsp119I | TTCGAA | 1 cut(s) | 391 |
| Bsp1286I | GDGCHC | 1 cut(s) | 27 |
| Bsp143I | GATC | 3 cut(s) | 41, 368, 401 |
| Bsp1720I | GCTNAGC | 1 cut(s) | 108 |
| Bsp68I | TCGCGA | 1 cut(s) | 192 |
| BspACI | CCGC | 3 cut(s) | 102, 152, 155 |
| BspANI | GGCC | 1 cut(s) | 215 |
| BspCNI | CTCAG | 3 cut(s) | 100, 481, 669 |
| BspDI | ATCGAT | 1 cut(s) | 44 |
| BspFNI | CGCG | 1 cut(s) | 192 |
| BspHI | TCATGA | 2 cut(s) | 199, 277 |
| BspLI | GGNNCC | 2 cut(s) | 150, 234 |
| BspPI | GGATC | 1 cut(s) | 409 |
| BspT104I | TTCGAA | 1 cut(s) | 391 |
| BspT107I | GGYRCC | 2 cut(s) | 148, 232 |
| BsrI | ACTGG | 2 cut(s) | 485, 703 |
| BssECI | CCNNGG | 4 cut(s) | 210, 328, 424, 607 |
| BssMI | GATC | 3 cut(s) | 41, 368, 401 |
| BssNI | GRCGYC | 1 cut(s) | 185 |
| BssT1I | CCWWGG | 2 cut(s) | 328, 424 |
| Bst4CI | ACNGT | 1 cut(s) | 148 |
| BstACI | GRCGYC | 1 cut(s) | 185 |
| BstBI | TTCGAA | 1 cut(s) | 391 |
| BstC8I | GCNNGC | 1 cut(s) | 354 |
| BstDEI | CTNAG | 4 cut(s) | 8, 108, 468, 677 |
| BstDSI | CCRYGG | 1 cut(s) | 210 |
| BstEII | GGTNACC | 2 cut(s) | 251, 755 |
| BstF5I | GGATG | 3 cut(s) | 184, 338, 760 |
| BstFNI | CGCG | 1 cut(s) | 192 |
| BstKTI | GATC | 3 cut(s) | 44, 371, 404 |
| BstMAI | GTCTC | 4 cut(s) | 192, 516, 619, 673 |
| BstMBI | GATC | 3 cut(s) | 41, 368, 401 |
| BstMWI | GCNNNNNNNGC | 1 cut(s) | 420 |
| BstPI | GGTNACC | 2 cut(s) | 251, 755 |
| BstUI | CGCG | 1 cut(s) | 192 |
| BstV1I | GCAGC | 2 cut(s) | 100, 421 |
| Bsu15I | ATCGAT | 1 cut(s) | 44 |
| BsuRI | GGCC | 1 cut(s) | 215 |
| BsuTUI | ATCGAT | 1 cut(s) | 44 |
| BtgI | CCRYGG | 1 cut(s) | 210 |
| BtrI | CACGTC | 1 cut(s) | 589 |
| BtsCI | GGATG | 3 cut(s) | 184, 338, 760 |
| BtsI | GCAGTG | 1 cut(s) | 40 |
| BtsIMutI | CAGTG | 3 cut(s) | 40, 674, 710 |
| BtuMI | TCGCGA | 1 cut(s) | 192 |
| Cac8I | GCNNGC | 1 cut(s) | 354 |
| CciI | TCATGA | 2 cut(s) | 199, 277 |
| ClaI | ATCGAT | 1 cut(s) | 44 |
| CseI | GACGC | 1 cut(s) | 174 |
| Csp6I | GTAC | 1 cut(s) | 233 |
| CviAII | CATG | 3 cut(s) | 200, 278, 372 |
| CviQI | GTAC | 1 cut(s) | 233 |
| DdeI | CTNAG | 4 cut(s) | 8, 108, 468, 677 |
| DpnI | GATC | 3 cut(s) | 43, 370, 403 |
| DpnII | GATC | 3 cut(s) | 41, 368, 401 |
| EaeI | YGGCCR | 1 cut(s) | 213 |
| Eco130I | CCWWGG | 2 cut(s) | 328, 424 |
| Eco91I | GGTNACC | 2 cut(s) | 251, 755 |
| EcoO65I | GGTNACC | 2 cut(s) | 251, 755 |
| EcoRI | GAATTC | 1 cut(s) | 692 |
| EcoT14I | CCWWGG | 2 cut(s) | 328, 424 |
| ErhI | CCWWGG | 2 cut(s) | 328, 424 |
| Esp3I | CGTCTC | 1 cut(s) | 192 |
| FaeI | CATG | 3 cut(s) | 203, 281, 375 |
| FaiI | YATR | 7 cut(s) | 201, 279, 373, 377, 421, 549, 641 |
| FatI | CATG | 3 cut(s) | 199, 277, 371 |
| Fnu4HI | GCNGC | 4 cut(s) | 89, 152, 155, 435 |
| FokI | GGATG | 3 cut(s) | 191, 345, 747 |
| Fsp4HI | GCNGC | 4 cut(s) | 89, 152, 155, 435 |
| FspBI | CTAG | 1 cut(s) | 114 |
| GluI | GCNGC | 4 cut(s) | 89, 152, 155, 435 |
| GsaI | CCCAGC | 1 cut(s) | 463 |
| GsuI | CTGGAG | 1 cut(s) | 508 |
| HaeIII | GGCC | 1 cut(s) | 215 |
| HgaI | GACGC | 1 cut(s) | 174 |
| Hin1I | GRCGYC | 1 cut(s) | 185 |
| Hin1II | CATG | 3 cut(s) | 203, 281, 375 |
| HincII | GTYRAC | 1 cut(s) | 496 |
| HindII | GTYRAC | 1 cut(s) | 496 |
| HinfI | GANTC | 2 cut(s) | 466, 497 |
| HphI | GGTGA | 3 cut(s) | 29, 152, 263 |
| Hpy166II | GTNNAC | 2 cut(s) | 496, 736 |
| Hpy188I | TCNGA | 1 cut(s) | 9 |
| Hpy188III | TCNNGA | 6 cut(s) | 191, 200, 261, 278, 487, 521 |
| Hpy8I | GTNNAC | 2 cut(s) | 496, 736 |
| Hpy99I | CGWCG | 2 cut(s) | 170, 173 |
| HpyAV | CCTTC | 1 cut(s) | 246 |
| HpyCH4III | ACNGT | 1 cut(s) | 148 |
| HpyCH4IV | ACGT | 2 cut(s) | 165, 588 |
| HpyCH4V | TGCA | 6 cut(s) | 288, 356, 437, 620, 674, 727 |
| HpyF10VI | GCNNNNNNNGC | 1 cut(s) | 420 |
| HpyF3I | CTNAG | 4 cut(s) | 8, 108, 468, 677 |
| HpySE526I | ACGT | 2 cut(s) | 165, 588 |
| Hsp92I | GRCGYC | 1 cut(s) | 185 |
| Hsp92II | CATG | 3 cut(s) | 203, 281, 375 |
| KpnI | GGTACC | 1 cut(s) | 236 |
| Kzo9I | GATC | 3 cut(s) | 41, 368, 401 |
| LmnI | GCTCC | 2 cut(s) | 104, 474 |
| Lsp1109I | GCAGC | 2 cut(s) | 100, 421 |
| MaeI | CTAG | 1 cut(s) | 114 |
| MaeII | ACGT | 2 cut(s) | 165, 588 |
| MaeIII | GTNAC | 5 cut(s) | 17, 251, 510, 601, 755 |
| MalI | GATC | 3 cut(s) | 43, 370, 403 |
| MboI | GATC | 3 cut(s) | 41, 368, 401 |
| MboII | GAAGA | 1 cut(s) | 688 |
| MhlI | GDGCHC | 1 cut(s) | 27 |
| MluCI | AATT | 3 cut(s) | 127, 217, 692 |
| MlyI | GAGTC | 2 cut(s) | 460, 491 |
| MmeI | TCCRAC | 1 cut(s) | 564 |
| MseI | TTAA | 1 cut(s) | 630 |
| MslI | CAYNNNNRTG | 1 cut(s) | 743 |
| MvnI | CGCG | 1 cut(s) | 192 |
| MwoI | GCNNNNNNNGC | 1 cut(s) | 420 |
| NdeII | GATC | 3 cut(s) | 41, 368, 401 |
| NlaIII | CATG | 3 cut(s) | 203, 281, 375 |
| NlaIV | GGNNCC | 2 cut(s) | 150, 234 |
| NmuCI | GTSAC | 3 cut(s) | 17, 251, 510 |
| NruI | TCGCGA | 1 cut(s) | 192 |
| NspV | TTCGAA | 1 cut(s) | 391 |
| OliI | CACNNNNGTG | 1 cut(s) | 743 |
| PagI | TCATGA | 2 cut(s) | 199, 277 |
| PkrI | GCNGC | 4 cut(s) | 90, 153, 156, 436 |
| PleI | GAGTC | 2 cut(s) | 460, 491 |
| PpsI | GAGTC | 2 cut(s) | 460, 491 |
| PspEI | GGTNACC | 2 cut(s) | 251, 755 |
| PspFI | CCCAGC | 1 cut(s) | 459 |
| PspN4I | GGNNCC | 2 cut(s) | 150, 234 |
| RruI | TCGCGA | 1 cut(s) | 192 |
| RsaI | GTAC | 1 cut(s) | 234 |
| RsaNI | GTAC | 1 cut(s) | 233 |
| RseI | CAYNNNNRTG | 1 cut(s) | 743 |
| SaqAI | TTAA | 1 cut(s) | 630 |
| SatI | GCNGC | 4 cut(s) | 89, 152, 155, 435 |
| Sau3AI | GATC | 3 cut(s) | 41, 368, 401 |
| SchI | GAGTC | 2 cut(s) | 460, 491 |
| SduI | GDGCHC | 1 cut(s) | 27 |
| SfuI | TTCGAA | 1 cut(s) | 391 |
| SmiMI | CAYNNNNRTG | 1 cut(s) | 743 |
| Sse9I | AATT | 3 cut(s) | 127, 217, 692 |
| SsiI | CCGC | 3 cut(s) | 102, 152, 155 |
| SspMI | CTAG | 1 cut(s) | 114 |
| StyI | CCWWGG | 2 cut(s) | 328, 424 |
| TaaI | ACNGT | 1 cut(s) | 148 |
| TaiI | ACGT | 2 cut(s) | 168, 591 |
| TaqI | TCGA | 7 cut(s) | 44, 224, 260, 343, 391, 404, 520 |
| TaqII | GACCGA | 1 cut(s) | 498 |
| TasI | AATT | 3 cut(s) | 127, 217, 692 |
| TauI | GCSGC | 2 cut(s) | 154, 157 |
| Tru1I | TTAA | 1 cut(s) | 630 |
| Tru9I | TTAA | 1 cut(s) | 630 |
| TscAI | CASTG | 3 cut(s) | 40, 681, 710 |
| TseFI | GTSAC | 3 cut(s) | 17, 251, 510 |
| TseI | GCWGC | 2 cut(s) | 88, 434 |
| Tsp45I | GTSAC | 3 cut(s) | 17, 251, 510 |
| TspDTI | ATGAA | 4 cut(s) | 81, 188, 294, 327 |
| TspGWI | ACGGA | 1 cut(s) | 589 |
| TspRI | CASTG | 3 cut(s) | 40, 681, 710 |
| XapI | RAATTY | 1 cut(s) | 692 |
| XspI | CTAG | 1 cut(s) | 114 |