pycom10g15050

Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
pyrus_communis
Chr10
OG0006052
Physical Location & Seq
Forward (+)
18382374 .. 18385809
3436 bp
Loading structure...
UTR
Exon/CDS
Intron
N/A

Sequence Viewer

Length: 1473 bp
ATGGAGGGTAAAGAAGATGGGGAAGCATACGAAGAGCGGCCTTCGTTGCCTACTCAGGTTTTGCAGGAAATATCTGAGGAGGCATTTAAAGTGGCAGGGGAAACATTGCAAAATGTGATCTCAAGTAATTCGAGCATGCCACCATTGGCACCGGGGCATACGCGCTCCCAAAGTGAAGTTGTAAGTATGACACACAAACGGAGCAATAGCTTTCAAAAATTGAAAACTCAGATGCAGAAGGCTTGGAGATGGGGTGGAAGTTCACGGGATGGTTTGCGGTTGTCTTTCAATCCTGAGGTTTTGGCAAACCAAAAACGCCAGTGGTATCAGCGTCACTCCAAATCAAAGGGCCATATAAAATATACCGAGCCAAGTTCACTCTTTGAGCATTTTATTATTGCGGGGCTTCATCCTGATGCTAACCTTGACACTGCGGAGGATGCATTTGTTAAAAGAAAGAAATGGGAGATGGAGATGATAAACTGTGGAATTGTTGACCTTAAATTGCTACAGCAGCGGGGACCTCCAATTCCTACATTAGAACCTCAGATACTTTTTAAATATCCTCCTGGGAAGCGGTTTGATATGCGTTTGACAGATTTAGCTTCCTTTTGTTTTCCTGGAGGGGTTAAGGCACGGTTATTGGAGAAGACTCCATCACTAAGTGATTTAAATCAAGTTGTTTATGGACAGGAGCATTTAGGCAAAGATGATTTGTCATTTATTTTCTCACTCAAGGTGGCAGACAATGCAACACTTTATGGTGTTTGCCTACACGTGTCAGAAATTGTTCAGAGGCCTCCTGCTATCTTAGGCATCTCATCACCTAATTCTCATTCGACGGGAGGACTCTTCCGCTTTTTGGTTTCTGCACCTCGATGCTACTGTGTGCTATCCAGATTTCCTTTTTTTGAGTTACATTACGAGATGCTGAATAGTATCATTCAACAGGAGCGTCTGAAGCGAATAACACAATTTGCTAGTGAAATGGCCCTCAATGATTTTGTCCCTACATTGCCCAAAGTACAAGATTATGATGATGAGTCCCCTGAGAGGGAGTCTTTTGATAATTGGATGGACTCCGCAATACCAGTTAACAGTTCAATTGCACTTACAGTTGCTGGTGCAGGAATCAGACCGGAGGATGAGACTCCACCTTCTTCACTCAAGATATGGGAACTGCAGTCCCCTGAAAGTGTTTCTGCTAGTGAAAGTTCAGATTTTTGTCAAGTACGGTATTTAGACAAGGATGGTAGAAAGGATTCACAATGTTCTGATGACTATGGTTTTGAGGCCTCAGAAACTCGTTCAGAGGCTTCAGAAAGAATATGCGCAATCTATGGAAATGACCATACTTCTCCAGAGGTTGGGACATCTTTCTCCACCAGGAATCGCACATTGGAGCGTCTTGGCAGTTCTGAATCTCTATTCAGGCTTTGTCTATATATGCTGCTATATGAGATTAAAACTTGA
Functional Annotation
Gene Ontology
Molecular Function
Biological Process
Cellular Component
No ontology terms assigned.
KEGG Pathways
Metabolic & Signaling
No pathways identified.
Pfam Domains
Protein Families
DENN dDENN uDENN

Protein Analysis

491

Amino Acids

55.33

Weight (kDa)

5.61

Isoelectric Point (pI)

51.59

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
uDENN PF03456 182 - 259 3.1e-07 uDENN domain
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
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Publication-ready
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Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
Acc16I TGCGCA 1 cut(s) 1333
AccB1I GGYRCC 1 cut(s) 148
AccB7I CCANNNNNTGG 1 cut(s) 1367
AccBSI CCGCTC 1 cut(s) 37
AccII CGCG 1 cut(s) 163
AciI CCGC 8 cut(s) 37, 277, 401, 434, 517, 577, 856, 1083
AcuI CTGAAG 2 cut(s) 980, 1302
AcvI CACGTG 1 cut(s) 778
AdeI CACNNNGTG 1 cut(s) 665
AfaI GTAC 2 cut(s) 1026, 1233
AfiI CCNNNNNNNGG 4 cut(s) 862, 1053, 1054, 1367
AflIII ACRYGT 2 cut(s) 775, 777
AgsI TTSAA 5 cut(s) 215, 223, 289, 947, 1104
AjnI CCWGG 3 cut(s) 568, 619, 1385
AjuI GAANNNNNNNTTGG 2 cut(s) 1382, 1414
AluBI AGCT 2 cut(s) 210, 605
AluI AGCT 2 cut(s) 210, 605
Alw26I GTCTC 1 cut(s) 1142
AlwNI CAGNNNCTG 1 cut(s) 1121
AoxI GGCC 5 cut(s) 38, 349, 797, 990, 1293
ApeKI GCWGC 2 cut(s) 514, 1450
ArsI GACNNNNNNTTYG 2 cut(s) 1271, 1303
Asp700I GAANNNNTTC 2 cut(s) 789, 1261
AspLEI GCGC 2 cut(s) 165, 1334
AspS9I GGNCC 3 cut(s) 349, 521, 991
AsuC2I CCSGG 1 cut(s) 153
AsuHPI GGTGA 1 cut(s) 816
AvaII GGWCC 1 cut(s) 521
AxyI CCTNAGG 1 cut(s) 294
BanI GGYRCC 1 cut(s) 148
BbrPI CACGTG 1 cut(s) 778
BbsI GAAGAC 1 cut(s) 656
BbvI GCAGC 2 cut(s) 526, 1437
BccI CCATC 7 cut(s) 11, 243, 263, 463, 664, 1069, 1244
BciT130I CCWGG 3 cut(s) 570, 621, 1387
BcnI CCSGG 1 cut(s) 153
BcoDI GTCTC 1 cut(s) 1142
BfaI CTAG 2 cut(s) 981, 1206
BfmI CTRYAG 2 cut(s) 509, 1181
BisI GCNGC 3 cut(s) 38, 515, 1451
BlsI GCNGC 3 cut(s) 39, 516, 1452
Bme1390I CCNGG 4 cut(s) 153, 570, 621, 1387
Bme18I GGWCC 1 cut(s) 521
BmgT120I GGNCC 3 cut(s) 349, 521, 991
BmiI GGNNCC 2 cut(s) 150, 522
BmrFI CCNGG 4 cut(s) 153, 570, 621, 1387
BmsI GCATC 6 cut(s) 222, 406, 430, 825, 869, 918
BpiI GAAGAC 1 cut(s) 656
BpmI CTGGAG 2 cut(s) 642, 1344
BpuEI CTTGAG 3 cut(s) 106, 719, 1151
BpuMI CCSGG 1 cut(s) 153
BsaAI YACGTR 1 cut(s) 778
BsaBI GATNNNNATC 1 cut(s) 672
BsaJI CCNNGG 2 cut(s) 152, 569
BsaWI WCCGGW 1 cut(s) 1138
BsaXI ACNNNNNCTCC 2 cut(s) 238, 268
Bsc4I CCNNNNNNNGG 4 cut(s) 862, 1053, 1054, 1367
Bse1I ACTGG 2 cut(s) 319, 1091
Bse21I CCTNAGG 1 cut(s) 294
Bse3DI GCAATG 2 cut(s) 104, 1013
Bse8I GATNNNNATC 1 cut(s) 672
BseBI CCWGG 3 cut(s) 570, 621, 1387
BseDI CCNNGG 2 cut(s) 152, 569
BseGI GGATG 6 cut(s) 274, 409, 445, 1080, 1150, 1255
BseJI GATNNNNATC 1 cut(s) 672
BseLI CCNNNNNNNGG 4 cut(s) 862, 1053, 1054, 1367
BseMI GCAATG 2 cut(s) 104, 1013
BseMII CTCAG 7 cut(s) 66, 68, 242, 285, 560, 1041, 1311
BseNI ACTGG 2 cut(s) 319, 1091
BseRI GAGGAG 1 cut(s) 92
BseXI GCAGC 2 cut(s) 526, 1437
BsgI GTGCAG 2 cut(s) 855, 1146
Bsh1236I CGCG 1 cut(s) 163
BshFI GGCC 5 cut(s) 40, 351, 799, 992, 1295
BshNI GGYRCC 1 cut(s) 148
BsiSI CCGG 2 cut(s) 152, 1139
BslFI GGGAC 5 cut(s) 534, 992, 1030, 1171, 1384
BslI CCNNNNNNNGG 4 cut(s) 862, 1053, 1054, 1367
BsmAI GTCTC 1 cut(s) 1142
BsmFI GGGAC 5 cut(s) 534, 992, 1030, 1171, 1384
BsnI GGCC 5 cut(s) 40, 351, 799, 992, 1295
Bsp143I GATC 1 cut(s) 117
BspACI CCGC 8 cut(s) 37, 277, 401, 434, 517, 577, 856, 1083
BspANI GGCC 5 cut(s) 40, 351, 799, 992, 1295
BspCNI CTCAG 7 cut(s) 67, 67, 241, 286, 559, 1042, 1310
BspFNI CGCG 1 cut(s) 163
BspLI GGNNCC 2 cut(s) 150, 522
BspMAI CTGCAG 1 cut(s) 1185
BspQI GCTCTTC 1 cut(s) 27
BspT107I GGYRCC 1 cut(s) 148
BsrBI CCGCTC 1 cut(s) 37
BsrDI GCAATG 2 cut(s) 104, 1013
BsrI ACTGG 2 cut(s) 319, 1091
BssECI CCNNGG 2 cut(s) 152, 569
BssMI GATC 1 cut(s) 117
Bst2UI CCWGG 3 cut(s) 570, 621, 1387
Bst4CI ACNGT 6 cut(s) 485, 639, 887, 1100, 1117, 1236
Bst6I CTCTTC 2 cut(s) 27, 857
BstAPI GCANNNNNTGC 1 cut(s) 749
BstBAI YACGTR 1 cut(s) 778
BstC8I GCNNGC 1 cut(s) 137
BstDEI CTNAG 9 cut(s) 54, 75, 228, 294, 546, 662, 811, 1050, 1297
BstF5I GGATG 6 cut(s) 274, 409, 445, 1080, 1150, 1255
BstFNI CGCG 1 cut(s) 163
BstHHI GCGC 2 cut(s) 165, 1334
BstKTI GATC 1 cut(s) 120
BstMAI GTCTC 1 cut(s) 1142
BstMBI GATC 1 cut(s) 117
BstMWI GCNNNNNNNGC 5 cut(s) 46, 440, 514, 749, 961
BstNI CCWGG 3 cut(s) 570, 621, 1387
BstNSI RCATGY 1 cut(s) 139
BstSCI CCNGG 4 cut(s) 151, 568, 619, 1385
BstSFI CTRYAG 2 cut(s) 509, 1181
BstUI CGCG 1 cut(s) 163
BstV1I GCAGC 2 cut(s) 526, 1437
BstV2I GAAGAC 1 cut(s) 656
Bsu36I CCTNAGG 1 cut(s) 294
BsuRI GGCC 5 cut(s) 40, 351, 799, 992, 1295
BtsCI GGATG 6 cut(s) 274, 409, 445, 1080, 1150, 1255
BtsI GCAGTG 1 cut(s) 429
BtsIMutI CAGTG 2 cut(s) 326, 429
Cac8I GCNNGC 1 cut(s) 137
CaiI CAGNNNCTG 1 cut(s) 1121
CfoI GCGC 2 cut(s) 165, 1334
Cfr13I GGNCC 3 cut(s) 349, 521, 991
CseI GACGC 3 cut(s) 320, 944, 1394
Csp6I GTAC 2 cut(s) 1025, 1232
CviAII CATG 1 cut(s) 136
CviQI GTAC 2 cut(s) 1025, 1232
DdeI CTNAG 9 cut(s) 54, 75, 228, 294, 546, 662, 811, 1050, 1297
DpnI GATC 1 cut(s) 119
DpnII GATC 1 cut(s) 117
DraI TTTAAA 3 cut(s) 88, 559, 672
DraIII CACNNNGTG 1 cut(s) 665
Eam1104I CTCTTC 2 cut(s) 27, 857
EarI CTCTTC 2 cut(s) 27, 857
Eco147I AGGCCT 2 cut(s) 799, 1295
Eco47I GGWCC 1 cut(s) 521
Eco57I CTGAAG 2 cut(s) 980, 1302
Eco72I CACGTG 1 cut(s) 778
Eco81I CCTNAGG 1 cut(s) 294
EcoO109I RGGNCCY 1 cut(s) 521
EcoRII CCWGG 3 cut(s) 568, 619, 1385
EcoT22I ATGCAT 1 cut(s) 445
FaeI CATG 1 cut(s) 139
FaqI GGGAC 5 cut(s) 534, 992, 1030, 1171, 1384
FatI CATG 1 cut(s) 135
FauI CCCGC 2 cut(s) 394, 510
Fnu4HI GCNGC 3 cut(s) 38, 515, 1451
FokI GGATG 6 cut(s) 281, 396, 452, 1087, 1157, 1262
Fsp4HI GCNGC 3 cut(s) 38, 515, 1451
FspBI CTAG 2 cut(s) 981, 1206
FspI TGCGCA 1 cut(s) 1333
GlaI GCGC 2 cut(s) 164, 1333
GluI GCNGC 3 cut(s) 38, 515, 1451
GsuI CTGGAG 2 cut(s) 642, 1344
HaeIII GGCC 5 cut(s) 40, 351, 799, 992, 1295
HapII CCGG 2 cut(s) 152, 1139
HgaI GACGC 3 cut(s) 320, 944, 1394
HhaI GCGC 2 cut(s) 165, 1334
Hin1II CATG 1 cut(s) 139
Hin6I GCGC 2 cut(s) 163, 1332
HinP1I GCGC 2 cut(s) 163, 1332
HincII GTYRAC 2 cut(s) 496, 1096
HindII GTYRAC 2 cut(s) 496, 1096
HpaI GTTAAC 1 cut(s) 1096
HpaII CCGG 2 cut(s) 152, 1139
HphI GGTGA 1 cut(s) 816
Hpy166II GTNNAC 4 cut(s) 263, 377, 496, 1096
Hpy188III TCNNGA 5 cut(s) 293, 413, 897, 1168, 1361
Hpy8I GTNNAC 4 cut(s) 263, 377, 496, 1096
Hpy99I CGWCG 1 cut(s) 844
HpyAV CCTTC 3 cut(s) 51, 232, 1167
HpyCH4III ACNGT 6 cut(s) 485, 639, 887, 1100, 1117, 1236
HpyCH4IV ACGT 1 cut(s) 777
HpyCH4V TGCA 9 cut(s) 64, 109, 235, 443, 752, 872, 1109, 1127, 1183
HpyF10VI GCNNNNNNNGC 5 cut(s) 46, 440, 514, 749, 961
HpyF3I CTNAG 9 cut(s) 54, 75, 228, 294, 546, 662, 811, 1050, 1297
HpySE526I ACGT 1 cut(s) 777
Hsp92II CATG 1 cut(s) 139
HspAI GCGC 2 cut(s) 163, 1332
KspAI GTTAAC 1 cut(s) 1096
Kzo9I GATC 1 cut(s) 117
LguI GCTCTTC 1 cut(s) 27
LmnI GCTCC 5 cut(s) 170, 201, 694, 952, 1402
Lsp1109I GCAGC 2 cut(s) 526, 1437
LweI GCATC 6 cut(s) 222, 406, 430, 825, 869, 918
MaeI CTAG 2 cut(s) 981, 1206
MaeII ACGT 1 cut(s) 777
MaeIII GTNAC 2 cut(s) 332, 915
MalI GATC 1 cut(s) 119
MbiI CCGCTC 1 cut(s) 37
MboI GATC 1 cut(s) 117
MboII GAAGA 5 cut(s) 26, 44, 661, 844, 1152
MfeI CAATTG 1 cut(s) 1104
MlyI GAGTC 6 cut(s) 646, 843, 1052, 1067, 1073, 1144
Mph1103I ATGCAT 1 cut(s) 445
MroXI GAANNNNTTC 2 cut(s) 789, 1261
MseI TTAA 8 cut(s) 87, 450, 501, 558, 630, 671, 1095, 1464
MslI CAYNNNNRTG 2 cut(s) 414, 877
MspA1I CMGCKG 1 cut(s) 517
MspI CCGG 2 cut(s) 152, 1139
MspR9I CCNGG 4 cut(s) 153, 570, 621, 1387
MunI CAATTG 1 cut(s) 1104
MvaI CCWGG 3 cut(s) 570, 621, 1387
MvnI CGCG 1 cut(s) 163
MwoI GCNNNNNNNGC 5 cut(s) 46, 440, 514, 749, 961
NciI CCSGG 1 cut(s) 153
NdeII GATC 1 cut(s) 117
NlaIII CATG 1 cut(s) 139
NlaIV GGNNCC 2 cut(s) 150, 522
NmuCI GTSAC 1 cut(s) 332
NsbI TGCGCA 1 cut(s) 1333
NsiI ATGCAT 1 cut(s) 445
NspI RCATGY 1 cut(s) 139
PaeI GCATGC 1 cut(s) 139
PceI AGGCCT 2 cut(s) 799, 1295
PciSI GCTCTTC 1 cut(s) 27
PdmI GAANNNNTTC 2 cut(s) 789, 1261
PfeI GAWTC 4 cut(s) 1131, 1262, 1390, 1421
PflMI CCANNNNNTGG 1 cut(s) 1367
PfoI TCCNGGA 1 cut(s) 619
PkrI GCNGC 3 cut(s) 39, 516, 1452
PleI GAGTC 6 cut(s) 646, 843, 1051, 1066, 1073, 1144
PmaCI CACGTG 1 cut(s) 778
PmlI CACGTG 1 cut(s) 778
PpsI GAGTC 6 cut(s) 646, 843, 1051, 1066, 1073, 1144
Ppu21I YACGTR 1 cut(s) 778
PpuMI RGGWCCY 1 cut(s) 521
Psp5II RGGWCCY 1 cut(s) 521
Psp6I CCWGG 3 cut(s) 568, 619, 1385
PspCI CACGTG 1 cut(s) 778
PspGI CCWGG 3 cut(s) 568, 619, 1385
PspN4I GGNNCC 2 cut(s) 150, 522
PspPI GGNCC 3 cut(s) 349, 521, 991
PspPPI RGGWCCY 1 cut(s) 521
PsrI GAACNNNNNNTAC 2 cut(s) 534, 566
PstI CTGCAG 1 cut(s) 1185
PstNI CAGNNNCTG 1 cut(s) 1121
RsaI GTAC 2 cut(s) 1026, 1233
RsaNI GTAC 2 cut(s) 1025, 1232
RseI CAYNNNNRTG 2 cut(s) 414, 877
SapI GCTCTTC 1 cut(s) 27
SaqAI TTAA 8 cut(s) 87, 450, 501, 558, 630, 671, 1095, 1464
SatI GCNGC 3 cut(s) 38, 515, 1451
Sau3AI GATC 1 cut(s) 117
Sau96I GGNCC 3 cut(s) 349, 521, 991
SchI GAGTC 6 cut(s) 646, 843, 1052, 1067, 1073, 1144
ScrFI CCNGG 4 cut(s) 153, 570, 621, 1387
SfaNI GCATC 6 cut(s) 222, 406, 430, 825, 869, 918
SfcI CTRYAG 2 cut(s) 509, 1181
SinI GGWCC 1 cut(s) 521
SmiI ATTTAAAT 1 cut(s) 672
SmiMI CAYNNNNRTG 2 cut(s) 414, 877
SmlI CTYRAG 3 cut(s) 121, 734, 1166
SmoI CTYRAG 3 cut(s) 121, 734, 1166
SphI GCATGC 1 cut(s) 139
SseBI AGGCCT 2 cut(s) 799, 1295
SsiI CCGC 8 cut(s) 37, 277, 401, 434, 517, 577, 856, 1083
SspMI CTAG 2 cut(s) 981, 1206
StuI AGGCCT 2 cut(s) 799, 1295
StyD4I CCNGG 4 cut(s) 151, 568, 619, 1385
SwaI ATTTAAAT 1 cut(s) 672
TaaI ACNGT 6 cut(s) 485, 639, 887, 1100, 1117, 1236
TaiI ACGT 1 cut(s) 780
TaqI TCGA 3 cut(s) 131, 839, 877
TatI WGTACW 1 cut(s) 1024
TauI GCSGC 1 cut(s) 40
TfiI GAWTC 4 cut(s) 1131, 1262, 1390, 1421
Tru1I TTAA 8 cut(s) 87, 450, 501, 558, 630, 671, 1095, 1464
Tru9I TTAA 8 cut(s) 87, 450, 501, 558, 630, 671, 1095, 1464
TscAI CASTG 2 cut(s) 326, 436
TseFI GTSAC 1 cut(s) 332
TseI GCWGC 2 cut(s) 514, 1450
Tsp45I GTSAC 1 cut(s) 332
TspDTI ATGAA 1 cut(s) 398
TspGWI ACGGA 1 cut(s) 214
TspRI CASTG 2 cut(s) 326, 436
Van91I CCANNNNNTGG 1 cut(s) 1367
VpaK11BI GGWCC 1 cut(s) 521
XceI RCATGY 1 cut(s) 139
XmnI GAANNNNTTC 2 cut(s) 789, 1261
XspI CTAG 2 cut(s) 981, 1206
Zsp2I ATGCAT 1 cut(s) 445
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.