Basic Information

Type: gene

Biological Identity

Species

rosa_chinensis

Chromosome

Orthogroup ID

OG0010500

Physical Location & Seq

Genomic Coordinates Reverse (-)

107582 .. 116129

Gene Structure 8548 bp

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UTR

Exon/CDS

Intron

Transcript / Protein ID

PRQ41485

Sequence Viewer

CDS Protein Promoter (2k)

Length: 1491 bp

ATGGCGAGGTTCGCAGGGAACGGCTCGGAGAATCTCCGAGAAGAAGAAGAAGAAGAAGAAGAAGAAGAAGGGAAACGGCAGCAATCAGGTTCCGAACAGACAATATTGGAGATGGAAGCCAAAACCGAAATTTTGAGTGAAGTAGGATGGTTTATTCTCGGTGAAAATCAGCAACATCTTGGTCCCTACACATTTTCGGAGTTGCGCGAGCATTTCTTAAATGGCTACCTCACCCACTCTACGCTGGTCTGGTCACAAGGAAGAAGCGAATGGCAGCCACTGTCCTCAATTCCTAATTTGGTCACCCAACTTACTTGCCATGACCCAGTGCCCCCCAGTGGTAATGATGATGACTTTGAGAAATGGCAGAAGCAGATTTCTAAGGCAGAAGCAGATAGTGAAAGACCTTCAACACCGCCAGAGGGCGAGGAAGAGTTCATCGATGATGATGGCACTCAATATAAGTGGGATCGGGGTCTTAGGGCTTGGGTTCCTCAGGATAGCATGTTTGGGGTAGAGGAGATGACTTTCTTGCAAGAAGAGGAAGTCTTCATGAATGCCAAACTTTCTGACGACTCTTCAAGGGAGGAGGTTGATGCAACTGGAATTTTTTCTGATCCTTCTAAAGAAGAAGACACTGTTGTTAACTGTGAGGTAGAACAAGGGAATCCAAATTCAAAGAGAAAACTGTCGGATACGGAAGATGTGAAAAAGGAAGCTAATAAACCTCCTGATAGTTGGTTTGAGCTAAAGGTCAATTCACATGTTTATGTGACTGGATTACCCGATGATGTTACAGTTGACGAAGTGGTGGAGGTGTTTTCCAAGTGTGGGATAATAAAAGAGGATCCTGAATCAAAAAAGCCTCGTGTGAAGCTGTATACTGATAAAGCGACTGGAAAGAAAAAGGGAGATGCACTTGTTACATATTTGAAGGAGCCCTCAGTCGATTTGGCTCTCAAAATTTTGGATGGAACACCTCTGCGTCTTGGTAGCAAGGTTCTCATGTCAGTCACCCAAGCTAAGTTTGAGCAGAAAGGGGATAGATTTATTGCCAAACAAGCAGACAACAAGAGGAAAAAAAAACTGAAGAAGGTGGAAGAGAAGATGCTTGGCTGGGGTGGTCGTGATGATGCAAAACTGTTGATTCCAGCTACTGTTCTTCTTCGTTACATGTTCACTACTGCTGAAATGAGCGCAGATGAAAATTTACGTGCAGAATTGCAGGCAGATGTTGAGGAGGAATGTCAGAAGCTTGGTCCCGTGGACTCAGTCAAGGTTTGTGAGAATCATCCCCAGGGTGTTGTTTTGGTAAGATTCAAAGATAGGAAGGATGCTCAAAAGTGCATAGAGTTGATGAATGGAAGATGGTTTGGTGGTAGGCAGATACATGCAAGTGAGGATGATGGTTTAATTAACCATGCATTGGTCCGGAATCTGGATGATGATGCTGAACGCTTAGAGCAGTTTGCTTCCGAACTTGATGTATGA

Functional Annotation

Gene Ontology

Molecular Function
Biological Process
Cellular Component

GO:0000375 GO:0000377 GO:0000398 GO:0003674 GO:0003676 GO:0003723 GO:0005488 GO:0005575 GO:0005622 GO:0005623 GO:0005634 GO:0005654 GO:0005681 GO:0005684 GO:0005686 GO:0006139 GO:0006396 GO:0006397 GO:0006725 GO:0006807 GO:0008150 GO:0008152 GO:0008380 GO:0009987 GO:0010467 GO:0016070 GO:0016071 GO:0030532 GO:0031974 GO:0031981 GO:0032991 GO:0034641 GO:0043170 GO:0043226 GO:0043227 GO:0043229 GO:0043231 GO:0043233 GO:0044237 GO:0044238 GO:0044422 GO:0044424 GO:0044428 GO:0044446 GO:0044464 GO:0046483 GO:0070013 GO:0071704 GO:0090304 GO:0097159 GO:0097525 GO:0120114 GO:1901360 GO:1901363 GO:1990904

KEGG Pathways

Metabolic & Signaling

No pathways identified.

Pfam Domains

Protein Families

DUF4339 RRM_1

Protein Analysis

496

Amino Acids

56.23

Weight (kDa)

4.7

Isoelectric Point (pI)

48.4

Instability Index

Protein Domains (Pfam)

Domain Name	Pfam ID	Position	E-value	Description
GYF_2	PF14237	50 - 100	1.9e-16	GYF domain 2
RRM_1	PF00076	256 - 328	2.2e-07	RNA recognition motif
RRM_1	PF00076	410 - 464	3.5e-09	RNA recognition motif

Hydrophobicity Profile (Kyte-Doolittle)

AI Structure Prediction Report

Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter

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Align Labels (Cladogram)

Image

Tree File

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Publication-ready

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Orthologous Genes (Group: OG0010500)

Species	Orthologous Gene IDs
arabidopsis_thaliana	AT5G16260
fragaria_vesca	FvH4_6g00060
malus_domestica	MD00G1017100.v1.1 MD12G1261400.v1.1
prunus_persica	Prupe.6G365400_v2.0.a1 Prupe.6G365400_v2.0.a1 Prupe.6G365400_v2.0.a1
pyrus_communis	pycom02g06260 pycom04g22010 pycom04g22020 pycom12g24240
rosa_chinensis	RchiOBHm_Chr3g0447391
rosa_laevigata	RLG00000026003
rosa_multiflora	Rmu_ssc0000473.1_g000016
rosa_roxburghii	Rroxscaffold_6G00425590
rosa_rugosa	Rorug02G0601100
rosa_samantha	Rh3AG001200 Rh3BG000900 Rh3CG000900 Rh3DG001100
rosa_wichuraiana	Rw3G000060

Restriction Enzyme Sites

1 / 10

Enzyme	Recognition Site	Cut Count	Positions (bp)
AccB7I	CCANNNNNTGG	1 cut(s)	1426
AccI	GTMKAC	1 cut(s)	881
AccII	CGCG	1 cut(s)	207
AccIII	TCCGGA	1 cut(s)	1431
AciI	CCGC	1 cut(s)	416
AclWI	GGATC	4 cut(s)	477, 611, 842, 855
AcsI	RAATTY	5 cut(s)	129, 606, 673, 963, 1207
AcuI	CTGAAG	1 cut(s)	1109
AfiI	CCNNNNNNNGG	5 cut(s)	338, 422, 831, 1426, 1438
AflIII	ACRYGT	2 cut(s)	763, 1173
AgsI	TTSAA	5 cut(s)	411, 582, 678, 934, 1321
AjnI	CCWGG	1 cut(s)	1296
AluBI	AGCT	6 cut(s)	719, 748, 877, 1022, 1154, 1255
AluI	AGCT	6 cut(s)	719, 748, 877, 1022, 1154, 1255
AlwI	GGATC	4 cut(s)	477, 611, 842, 855
AlwNI	CAGNNNCTG	2 cut(s)	280, 1157
Aor13HI	TCCGGA	1 cut(s)	1431
ApeKI	GCWGC	2 cut(s)	79, 274
ApoI	RAATTY	5 cut(s)	129, 606, 673, 963, 1207
Asp700I	GAANNNNTTC	1 cut(s)	610
AspLEI	GCGC	2 cut(s)	207, 1199
AspS9I	GGNCC	3 cut(s)	182, 1259, 1429
AsuHPI	GGTGA	4 cut(s)	173, 223, 295, 1006
AvaII	GGWCC	3 cut(s)	182, 1259, 1429
AxyI	CCTNAGG	1 cut(s)	495
BaeGI	GKGCMC	1 cut(s)	333
BamHI	GGATCC	1 cut(s)	847
BanII	GRGCYC	1 cut(s)	942
BauI	CACGAG	1 cut(s)	867
BbsI	GAAGAC	2 cut(s)	541, 639
BbvI	GCAGC	2 cut(s)	91, 286
BccI	CCATC	6 cut(s)	106, 141, 443, 965, 1362, 1400
BceAI	ACGGC	2 cut(s)	37, 92
BciT130I	CCWGG	1 cut(s)	1298
BciVI	GTATCC	1 cut(s)	688
BfuI	GTATCC	1 cut(s)	688
BisI	GCNGC	2 cut(s)	80, 275
BlsI	GCNGC	2 cut(s)	81, 276
Bme1390I	CCNGG	1 cut(s)	1298
Bme18I	GGWCC	3 cut(s)	182, 1259, 1429
BmgT120I	GGNCC	3 cut(s)	182, 1259, 1429
BmiI	GGNNCC	6 cut(s)	91, 184, 492, 849, 939, 1261
BmrFI	CCNGG	1 cut(s)	1298
BmrI	ACTGGG	2 cut(s)	320, 330
BmsI	GCATC	6 cut(s)	586, 904, 1098, 1123, 1324, 1438
BmuI	ACTGGG	2 cut(s)	320, 330
BpiI	GAAGAC	2 cut(s)	541, 639
Bsa29I	ATCGAT	1 cut(s)	441
BsaAI	YACGTR	1 cut(s)	1214
BsaJI	CCNNGG	3 cut(s)	1263, 1296, 1297
BsaWI	WCCGGW	1 cut(s)	1431
Bsc4I	CCNNNNNNNGG	5 cut(s)	338, 422, 831, 1426, 1438
Bse1I	ACTGG	5 cut(s)	326, 336, 607, 781, 901
Bse21I	CCTNAGG	1 cut(s)	495
BseAI	TCCGGA	1 cut(s)	1431
BseBI	CCWGG	1 cut(s)	1298
BseCI	ATCGAT	1 cut(s)	441
BseDI	CCNNGG	3 cut(s)	1263, 1296, 1297
BseGI	GGATG	6 cut(s)	152, 976, 1291, 1339, 1408, 1447
BseLI	CCNNNNNNNGG	5 cut(s)	338, 422, 831, 1426, 1438
BseMII	CTCAG	3 cut(s)	509, 957, 1284
BseNI	ACTGG	5 cut(s)	326, 336, 607, 781, 901
BseRI	GAGGAG	3 cut(s)	533, 602, 1253
BseSI	GKGCMC	1 cut(s)	333
BseXI	GCAGC	2 cut(s)	91, 286
BseYI	CCCAGC	1 cut(s)	1116
BsgI	GTGCAG	1 cut(s)	1236
Bsh1236I	CGCG	1 cut(s)	207
BshVI	ATCGAT	1 cut(s)	441
BsiSI	CCGG	1 cut(s)	1432
BslFI	GGGAC	2 cut(s)	168, 1245
BslI	CCNNNNNNNGG	5 cut(s)	338, 422, 831, 1426, 1438
BsmFI	GGGAC	2 cut(s)	168, 1245
BsmI	GAATGC	1 cut(s)	562
Bsp1286I	GDGCHC	2 cut(s)	333, 942
Bsp13I	TCCGGA	1 cut(s)	1431
Bsp143I	GATC	3 cut(s)	469, 616, 847
BspACI	CCGC	1 cut(s)	416
BspCNI	CTCAG	3 cut(s)	508, 956, 1283
BspDI	ATCGAT	1 cut(s)	441
BspEI	TCCGGA	1 cut(s)	1431
BspFNI	CGCG	1 cut(s)	207
BspHI	TCATGA	1 cut(s)	552
BspLI	GGNNCC	6 cut(s)	91, 184, 492, 849, 939, 1261
BspPI	GGATC	4 cut(s)	477, 611, 842, 855
BsrI	ACTGG	5 cut(s)	326, 336, 607, 781, 901
BssECI	CCNNGG	3 cut(s)	1263, 1296, 1297
BssMI	GATC	3 cut(s)	469, 616, 847
BssNAI	GTATAC	1 cut(s)	882
BssSI	CACGAG	1 cut(s)	867
Bst1107I	GTATAC	1 cut(s)	882
Bst2BI	CACGAG	1 cut(s)	867
Bst2UI	CCWGG	1 cut(s)	1298
Bst4CI	ACNGT	7 cut(s)	282, 640, 650, 690, 799, 1143, 1159
Bst6I	CTCTTC	4 cut(s)	426, 534, 583, 1095
BstBAI	YACGTR	1 cut(s)	1214
BstC8I	GCNNGC	2 cut(s)	209, 1227
BstDEI	CTNAG	7 cut(s)	381, 479, 495, 943, 1023, 1270, 1459
BstDSI	CCRYGG	1 cut(s)	1263
BstEII	GGTNACC	1 cut(s)	301
BstF5I	GGATG	6 cut(s)	152, 976, 1291, 1339, 1408, 1447
BstFNI	CGCG	1 cut(s)	207
BstHHI	GCGC	2 cut(s)	207, 1199
BstKTI	GATC	3 cut(s)	472, 619, 850
BstMBI	GATC	3 cut(s)	469, 616, 847
BstMWI	GCNNNNNNNGC	2 cut(s)	11, 1061
BstNI	CCWGG	1 cut(s)	1298
BstNSI	RCATGY	4 cut(s)	508, 767, 1177, 1394
BstPI	GGTNACC	1 cut(s)	301
BstSCI	CCNGG	1 cut(s)	1296
BstSLI	GKGCMC	1 cut(s)	333
BstUI	CGCG	1 cut(s)	207
BstV1I	GCAGC	2 cut(s)	91, 286
BstV2I	GAAGAC	2 cut(s)	541, 639
BstX2I	RGATCY	1 cut(s)	847
BstYI	RGATCY	1 cut(s)	847
BstZ17I	GTATAC	1 cut(s)	882
Bsu15I	ATCGAT	1 cut(s)	441
Bsu36I	CCTNAGG	1 cut(s)	495
BsuI	GTATCC	1 cut(s)	688
BsuTUI	ATCGAT	1 cut(s)	441
BtgI	CCRYGG	1 cut(s)	1263
BtsCI	GGATG	6 cut(s)	152, 976, 1291, 1339, 1408, 1447
BtsIMutI	CAGTG	4 cut(s)	278, 333, 343, 636
Cac8I	GCNNGC	2 cut(s)	209, 1227
CaiI	CAGNNNCTG	2 cut(s)	280, 1157
CciI	TCATGA	1 cut(s)	552
CfoI	GCGC	2 cut(s)	207, 1199
Cfr13I	GGNCC	3 cut(s)	182, 1259, 1429
ClaI	ATCGAT	1 cut(s)	441
CseI	GACGC	1 cut(s)	974
CspCI	CAANNNNNGTGG	2 cut(s)	446, 481
CviAII	CATG	8 cut(s)	320, 505, 553, 764, 1006, 1174, 1391, 1421
DdeI	CTNAG	7 cut(s)	381, 479, 495, 943, 1023, 1270, 1459
DpnI	GATC	3 cut(s)	471, 618, 849
DpnII	GATC	3 cut(s)	469, 616, 847
Eam1104I	CTCTTC	4 cut(s)	426, 534, 583, 1095
EarI	CTCTTC	4 cut(s)	426, 534, 583, 1095
Eco24I	GRGCYC	1 cut(s)	942
Eco47I	GGWCC	3 cut(s)	182, 1259, 1429
Eco57I	CTGAAG	1 cut(s)	1109
Eco81I	CCTNAGG	1 cut(s)	495
Eco91I	GGTNACC	1 cut(s)	301
EcoO65I	GGTNACC	1 cut(s)	301
EcoRII	CCWGG	1 cut(s)	1296
EcoT22I	ATGCAT	1 cut(s)	1426
EcoT38I	GRGCYC	1 cut(s)	942
FaeI	CATG	8 cut(s)	323, 508, 556, 767, 1009, 1177, 1394, 1424
FaqI	GGGAC	2 cut(s)	168, 1245
FatI	CATG	8 cut(s)	319, 504, 552, 763, 1005, 1173, 1390, 1420
FblI	GTMKAC	1 cut(s)	881
Fnu4HI	GCNGC	2 cut(s)	80, 275
FokI	GGATG	6 cut(s)	159, 983, 1278, 1346, 1415, 1454
FriOI	GRGCYC	1 cut(s)	942
Fsp4HI	GCNGC	2 cut(s)	80, 275
GlaI	GCGC	2 cut(s)	206, 1198
GluI	GCNGC	2 cut(s)	80, 275
GsaI	CCCAGC	1 cut(s)	1120
HapII	CCGG	1 cut(s)	1432
HgaI	GACGC	1 cut(s)	974
HhaI	GCGC	2 cut(s)	207, 1199
Hin1II	CATG	8 cut(s)	323, 508, 556, 767, 1009, 1177, 1394, 1424
Hin6I	GCGC	2 cut(s)	205, 1197
HinP1I	GCGC	2 cut(s)	205, 1197
HincII	GTYRAC	2 cut(s)	646, 802
HindII	GTYRAC	2 cut(s)	646, 802
HindIII	AAGCTT	1 cut(s)	1253
HinfI	GANTC	9 cut(s)	31, 575, 667, 854, 1147, 1268, 1288, 1317, 1435
HpaI	GTTAAC	1 cut(s)	646
HpaII	CCGG	1 cut(s)	1432
HphI	GGTGA	4 cut(s)	173, 223, 295, 1006
Hpy166II	GTNNAC	5 cut(s)	646, 802, 882, 1179, 1267
Hpy188I	TCNGA	9 cut(s)	28, 38, 94, 199, 571, 616, 694, 1251, 1477
Hpy188III	TCNNGA	7 cut(s)	497, 553, 731, 851, 1127, 1432, 1439
Hpy8I	GTNNAC	5 cut(s)	646, 802, 882, 1179, 1267
HpyAV	CCTTC	6 cut(s)	62, 417, 630, 928, 1087, 1324
HpyCH4III	ACNGT	7 cut(s)	282, 640, 650, 690, 799, 1143, 1159
HpyCH4IV	ACGT	1 cut(s)	1213
HpyCH4V	TGCA	9 cut(s)	535, 599, 917, 1136, 1217, 1225, 1347, 1394, 1424
HpyF10VI	GCNNNNNNNGC	2 cut(s)	11, 1061
HpyF3I	CTNAG	7 cut(s)	381, 479, 495, 943, 1023, 1270, 1459
HpySE526I	ACGT	1 cut(s)	1213
Hsp92II	CATG	8 cut(s)	323, 508, 556, 767, 1009, 1177, 1394, 1424
HspAI	GCGC	2 cut(s)	205, 1197
Kpn2I	TCCGGA	1 cut(s)	1431
KspAI	GTTAAC	1 cut(s)	646
Kzo9I	GATC	3 cut(s)	469, 616, 847
LmnI	GCTCC	1 cut(s)	937
Lsp1109I	GCAGC	2 cut(s)	91, 286
LweI	GCATC	6 cut(s)	586, 904, 1098, 1123, 1324, 1438
MaeII	ACGT	1 cut(s)	1213
MaeIII	GTNAC	7 cut(s)	252, 301, 772, 793, 922, 1012, 1169
MalI	GATC	3 cut(s)	471, 618, 849
MboI	GATC	3 cut(s)	469, 616, 847
MflI	RGATCY	1 cut(s)	847
MhlI	GDGCHC	2 cut(s)	333, 942
MlyI	GAGTC	2 cut(s)	569, 1262
MmeI	TCCRAC	1 cut(s)	672
Mph1103I	ATGCAT	1 cut(s)	1426
MroI	TCCGGA	1 cut(s)	1431
MroXI	GAANNNNTTC	1 cut(s)	610
MseI	TTAA	4 cut(s)	218, 645, 1412, 1416
MslI	CAYNNNNRTG	2 cut(s)	768, 1395
MspI	CCGG	1 cut(s)	1432
MspR9I	CCNGG	1 cut(s)	1298
Mva1269I	GAATGC	1 cut(s)	562
MvaI	CCWGG	1 cut(s)	1298
MvnI	CGCG	1 cut(s)	207
MwoI	GCNNNNNNNGC	2 cut(s)	11, 1061
NdeII	GATC	3 cut(s)	469, 616, 847
NlaIII	CATG	8 cut(s)	323, 508, 556, 767, 1009, 1177, 1394, 1424
NlaIV	GGNNCC	6 cut(s)	91, 184, 492, 849, 939, 1261
NmuCI	GTSAC	4 cut(s)	252, 301, 772, 1012
NsiI	ATGCAT	1 cut(s)	1426
NspI	RCATGY	4 cut(s)	508, 767, 1177, 1394
PacI	TTAATTAA	1 cut(s)	1416
PagI	TCATGA	1 cut(s)	552
PasI	CCCWGGG	1 cut(s)	1297
PciI	ACATGT	2 cut(s)	763, 1173
PctI	GAATGC	1 cut(s)	562
PdmI	GAANNNNTTC	1 cut(s)	610
PfeI	GAWTC	7 cut(s)	31, 667, 854, 1147, 1288, 1317, 1435
PflFI	GACNNNGTC	1 cut(s)	1271
PflMI	CCANNNNNTGG	1 cut(s)	1426
PkrI	GCNGC	2 cut(s)	81, 276
PleI	GAGTC	2 cut(s)	569, 1262
PpsI	GAGTC	2 cut(s)	569, 1262
Ppu21I	YACGTR	1 cut(s)	1214
PscI	ACATGT	2 cut(s)	763, 1173
Psp6I	CCWGG	1 cut(s)	1296
PspEI	GGTNACC	1 cut(s)	301
PspFI	CCCAGC	1 cut(s)	1116
PspGI	CCWGG	1 cut(s)	1296
PspN4I	GGNNCC	6 cut(s)	91, 184, 492, 849, 939, 1261
PspPI	GGNCC	3 cut(s)	182, 1259, 1429
PstNI	CAGNNNCTG	2 cut(s)	280, 1157
PsuI	RGATCY	1 cut(s)	847
PsyI	GACNNNGTC	1 cut(s)	1271
RseI	CAYNNNNRTG	2 cut(s)	768, 1395
SaqAI	TTAA	4 cut(s)	218, 645, 1412, 1416
SatI	GCNGC	2 cut(s)	80, 275
Sau3AI	GATC	3 cut(s)	469, 616, 847
Sau96I	GGNCC	3 cut(s)	182, 1259, 1429
SchI	GAGTC	2 cut(s)	569, 1262
ScrFI	CCNGG	1 cut(s)	1298
SduI	GDGCHC	2 cut(s)	333, 942
SfaNI	GCATC	6 cut(s)	586, 904, 1098, 1123, 1324, 1438
SinI	GGWCC	3 cut(s)	182, 1259, 1429
SmiMI	CAYNNNNRTG	2 cut(s)	768, 1395
SsiI	CCGC	1 cut(s)	416
SspI	AATATT	1 cut(s)	105
StyD4I	CCNGG	1 cut(s)	1296
TaaI	ACNGT	7 cut(s)	282, 640, 650, 690, 799, 1143, 1159
TaiI	ACGT	1 cut(s)	1216
TaqI	TCGA	2 cut(s)	441, 948
TfiI	GAWTC	7 cut(s)	31, 667, 854, 1147, 1288, 1317, 1435
Tru1I	TTAA	4 cut(s)	218, 645, 1412, 1416
Tru9I	TTAA	4 cut(s)	218, 645, 1412, 1416
TscAI	CASTG	4 cut(s)	285, 333, 343, 643
TseFI	GTSAC	4 cut(s)	252, 301, 772, 1012
TseI	GCWGC	2 cut(s)	79, 274
Tsp45I	GTSAC	4 cut(s)	252, 301, 772, 1012
TspDTI	ATGAA	5 cut(s)	427, 541, 569, 1218, 1373
TspGWI	ACGGA	1 cut(s)	713
TspRI	CASTG	4 cut(s)	285, 333, 343, 643
Tth111I	GACNNNGTC	1 cut(s)	1271
Van91I	CCANNNNNTGG	1 cut(s)	1426
VpaK11BI	GGWCC	3 cut(s)	182, 1259, 1429
XapI	RAATTY	5 cut(s)	129, 606, 673, 963, 1207
XceI	RCATGY	4 cut(s)	508, 767, 1177, 1394
XmiI	GTMKAC	1 cut(s)	881
XmnI	GAANNNNTTC	1 cut(s)	610
Zsp2I	ATGCAT	1 cut(s)	1426

Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.