FvH4_5g13800

subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
fragaria_vesca
Fvb5
OG0007322
Physical Location & Seq
Reverse (-)
7796462 .. 7798463
2002 bp
Loading structure...
UTR
Exon/CDS
Intron
FvH4_5g13800.t1

Sequence Viewer

Length: 981 bp
ATGGGCTTCTCCTCGTTTATTGTCTTGGGCTTCATGGGCGGCGAGGTTGCTTTGTTTCTGGTCCAGGATTTTAATGTTCCGATTGATTGCGTCACGTTTTTAGTTGTGTTGTTTAATTTTGCTGTTGTGGGTGTGTTGGCTGTGTTCATGTCGAAAATGGCGATACTTGTGACACAAGGCTACTTGATTGTGATTGGGATGCTGGTTGCTTATTGGTTTACGTTGTTGCCGGAATGGACTACTTGGGTGCTGTTGGTGGCCATGGCATTGTATGATCTCGCCGCGGTTTTGCTGCCTGTTGGGCCGCTGAGGTTGTTGGTTGAGCTTGCGATTTCTAGAGATGAGGAAATTCCGGCTTTGGTGTATGAGGCCCGGCCTGTGGTGGCGTCTCAGGGTCCGAGAAGGGTTTGGAGAGATAGGAGGAATGAGAGTGAGAATAATGACAATGTTGGTTCTGGTTTGGGTGAGAATTTGAGTTCCGGGTTGAGCTCTAATGTGAATGCTAGTGTTGGGTTTGGTAACAGGAATGAGTCGAGTTTGGTTGGGGCTGAAGAGGGGAGGGTTGCGGATAGGGGTCAAGAGCTTTCTGTGCCGTTACTAGAGCAGATAACAAGTGCTCAGCTAGAGCAGATAACAAGTGCTCAGCAGCACGGGTTGGAGGATGCTGCGTCGGGTGAAAGTATGTTGCTGGAAGGTATTGGATTGGGATCTTCTGGTTCGATCAAGTTGGGATTGGGAGACTTTATATTCTATAGTGTTTTAGTTGGGAGGGCGGCGATGTATGATTTTATGACAGTGTATGCTTGCTATCTTGCTATTATAGGCGGTTTGGGAGTTACTTTGATACTGCTGGCTTTGTATCAGAAAGCTTTGCCAGCTCTTCCTGTGTCAATACTGCTTGGTGTACTGTTTTATGTACTGACCCGGTTCTTGCTTGAAGCCTTTGTTGTACAGTGTACTTTGAATCTCATCATGTTTTAG

Protein Analysis

327

Amino Acids

35.22

Weight (kDa)

4.48

Isoelectric Point (pI)

37.02

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
Presenilin PF01080 1 - 316 3.3e-99 Presenilin
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
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Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AccII CGCG 1 cut(s) 284
AciI CCGC 7 cut(s) 39, 282, 284, 305, 566, 773, 825
AclWI GGATC 1 cut(s) 715
AcoI YGGCCR 1 cut(s) 258
AcsI RAATTY 2 cut(s) 348, 469
AcuI CTGAAG 1 cut(s) 570
AcyI GRCGYC 1 cut(s) 386
AfaI GTAC 4 cut(s) 906, 918, 951, 958
AfiI CCNNNNNNNGG 1 cut(s) 379
AgsI TTSAA 2 cut(s) 938, 964
AjnI CCWGG 1 cut(s) 63
AluBI AGCT 6 cut(s) 325, 489, 583, 622, 869, 878
AluI AGCT 6 cut(s) 325, 489, 583, 622, 869, 878
Alw21I GWGCWC 3 cut(s) 491, 619, 643
Alw26I GTCTC 2 cut(s) 393, 732
AlwI GGATC 1 cut(s) 715
AoxI GGCC 4 cut(s) 258, 302, 369, 374
ApeKI GCWGC 3 cut(s) 292, 646, 665
ApoI RAATTY 2 cut(s) 348, 469
AspS9I GGNCC 4 cut(s) 61, 302, 370, 395
AsuC2I CCSGG 3 cut(s) 373, 481, 925
AsuHPI GGTGA 2 cut(s) 476, 686
AvaII GGWCC 2 cut(s) 61, 395
BalI TGGCCA 1 cut(s) 260
BanII GRGCYC 1 cut(s) 491
Bbv12I GWGCWC 3 cut(s) 491, 619, 643
BbvCI CCTCAGC 1 cut(s) 308
BbvI GCAGC 3 cut(s) 279, 652, 658
BceAI ACGGC 1 cut(s) 577
BciT130I CCWGG 1 cut(s) 65
BcnI CCSGG 3 cut(s) 373, 481, 925
BcoDI GTCTC 2 cut(s) 393, 732
BfaI CTAG 4 cut(s) 336, 504, 599, 623
BfmI CTRYAG 1 cut(s) 751
BglI GCCNNNNNGGC 1 cut(s) 301
BisI GCNGC 7 cut(s) 40, 282, 293, 305, 647, 666, 774
BlpI GCTNAGC 2 cut(s) 618, 642
BlsI GCNGC 7 cut(s) 41, 283, 294, 306, 648, 667, 775
Bme1390I CCNGG 4 cut(s) 65, 373, 481, 925
Bme18I GGWCC 2 cut(s) 61, 395
BmgT120I GGNCC 4 cut(s) 61, 302, 370, 395
BmiI GGNNCC 1 cut(s) 396
BmrFI CCNGG 4 cut(s) 65, 373, 481, 925
BmsI GCATC 2 cut(s) 189, 652
Bpu10I CCTNAGC 1 cut(s) 308
Bpu1102I GCTNAGC 2 cut(s) 618, 642
BpuMI CCSGG 3 cut(s) 373, 481, 925
BsaBI GATNNNNATC 1 cut(s) 706
BsaHI GRCGYC 1 cut(s) 386
BsaJI CCNNGG 2 cut(s) 261, 282
Bsc4I CCNNNNNNNGG 1 cut(s) 379
Bse8I GATNNNNATC 1 cut(s) 706
BseBI CCWGG 1 cut(s) 65
BseDI CCNNGG 2 cut(s) 261, 282
BseGI GGATG 2 cut(s) 204, 667
BseJI GATNNNNATC 1 cut(s) 706
BseLI CCNNNNNNNGG 1 cut(s) 379
BseMII CTCAG 4 cut(s) 299, 404, 632, 656
BseXI GCAGC 3 cut(s) 279, 652, 658
Bsh1236I CGCG 1 cut(s) 284
BshFI GGCC 4 cut(s) 260, 304, 371, 376
BsiHKAI GWGCWC 3 cut(s) 491, 619, 643
BsiSI CCGG 5 cut(s) 230, 353, 373, 480, 925
BslI CCNNNNNNNGG 1 cut(s) 379
BsmAI GTCTC 2 cut(s) 393, 732
BsmBI CGTCTC 1 cut(s) 393
BsmI GAATGC 1 cut(s) 505
BsnI GGCC 4 cut(s) 260, 304, 371, 376
Bsp1286I GDGCHC 3 cut(s) 491, 619, 643
Bsp1407I TGTACA 1 cut(s) 949
Bsp143I GATC 3 cut(s) 274, 707, 720
Bsp1720I GCTNAGC 2 cut(s) 618, 642
Bsp19I CCATGG 1 cut(s) 261
BspACI CCGC 7 cut(s) 39, 282, 284, 305, 566, 773, 825
BspANI GGCC 4 cut(s) 260, 304, 371, 376
BspCNI CTCAG 4 cut(s) 300, 403, 631, 655
BspFNI CGCG 1 cut(s) 284
BspLI GGNNCC 1 cut(s) 396
BspPI GGATC 1 cut(s) 715
BspQI GCTCTTC 1 cut(s) 885
BsrGI TGTACA 1 cut(s) 949
BssECI CCNNGG 2 cut(s) 261, 282
BssMI GATC 3 cut(s) 274, 707, 720
BssNI GRCGYC 1 cut(s) 386
BssT1I CCWWGG 1 cut(s) 261
Bst2UI CCWGG 1 cut(s) 65
Bst4CI ACNGT 3 cut(s) 796, 909, 954
Bst6I CTCTTC 2 cut(s) 546, 885
BstACI GRCGYC 1 cut(s) 386
BstAUI TGTACA 1 cut(s) 949
BstC8I GCNNGC 4 cut(s) 327, 805, 852, 876
BstDEI CTNAG 4 cut(s) 308, 390, 618, 642
BstDSI CCRYGG 2 cut(s) 261, 282
BstF5I GGATG 2 cut(s) 204, 667
BstFNI CGCG 1 cut(s) 284
BstKTI GATC 3 cut(s) 277, 710, 723
BstMAI GTCTC 2 cut(s) 393, 732
BstMBI GATC 3 cut(s) 274, 707, 720
BstMWI GCNNNNNNNGC 4 cut(s) 36, 301, 589, 875
BstNI CCWGG 1 cut(s) 65
BstSCI CCNGG 4 cut(s) 63, 371, 479, 923
BstSFI CTRYAG 1 cut(s) 751
BstUI CGCG 1 cut(s) 284
BstV1I GCAGC 3 cut(s) 279, 652, 658
BstX2I RGATCY 1 cut(s) 707
BstYI RGATCY 1 cut(s) 707
BsuRI GGCC 4 cut(s) 260, 304, 371, 376
BtgI CCRYGG 2 cut(s) 261, 282
BtgZI GCGATG 1 cut(s) 791
BtsCI GGATG 2 cut(s) 204, 667
BtsIMutI CAGTG 2 cut(s) 801, 959
Cac8I GCNNGC 4 cut(s) 327, 805, 852, 876
Cfr13I GGNCC 4 cut(s) 61, 302, 370, 395
Cfr42I CCGCGG 1 cut(s) 285
CseI GACGC 3 cut(s) 79, 375, 657
Csp6I GTAC 4 cut(s) 905, 917, 950, 957
CviAII CATG 4 cut(s) 34, 148, 262, 973
CviQI GTAC 4 cut(s) 905, 917, 950, 957
DdeI CTNAG 4 cut(s) 308, 390, 618, 642
DpnI GATC 3 cut(s) 276, 709, 722
DpnII GATC 3 cut(s) 274, 707, 720
EaeI YGGCCR 1 cut(s) 258
Eam1104I CTCTTC 2 cut(s) 546, 885
EarI CTCTTC 2 cut(s) 546, 885
Ecl136II GAGCTC 1 cut(s) 489
Eco130I CCWWGG 1 cut(s) 261
Eco24I GRGCYC 1 cut(s) 491
Eco47I GGWCC 2 cut(s) 61, 395
Eco53kI GAGCTC 1 cut(s) 489
Eco57I CTGAAG 1 cut(s) 570
EcoICRI GAGCTC 1 cut(s) 489
EcoRII CCWGG 1 cut(s) 63
EcoT14I CCWWGG 1 cut(s) 261
EcoT38I GRGCYC 1 cut(s) 491
ErhI CCWWGG 1 cut(s) 261
Esp3I CGTCTC 1 cut(s) 393
FaeI CATG 4 cut(s) 37, 151, 265, 976
FatI CATG 4 cut(s) 33, 147, 261, 972
Fnu4HI GCNGC 7 cut(s) 40, 282, 293, 305, 647, 666, 774
FokI GGATG 2 cut(s) 211, 674
FriOI GRGCYC 1 cut(s) 491
Fsp4HI GCNGC 7 cut(s) 40, 282, 293, 305, 647, 666, 774
FspBI CTAG 4 cut(s) 336, 504, 599, 623
GluI GCNGC 7 cut(s) 40, 282, 293, 305, 647, 666, 774
HaeIII GGCC 4 cut(s) 260, 304, 371, 376
HapII CCGG 5 cut(s) 230, 353, 373, 480, 925
HgaI GACGC 3 cut(s) 79, 375, 657
Hin1I GRCGYC 1 cut(s) 386
Hin1II CATG 4 cut(s) 37, 151, 265, 976
HindIII AAGCTT 1 cut(s) 867
HinfI GANTC 2 cut(s) 530, 964
HpaII CCGG 5 cut(s) 230, 353, 373, 480, 925
HphI GGTGA 2 cut(s) 476, 686
Hpy166II GTNNAC 3 cut(s) 219, 905, 957
Hpy188I TCNGA 3 cut(s) 81, 399, 864
Hpy188III TCNNGA 2 cut(s) 336, 578
Hpy8I GTNNAC 3 cut(s) 219, 905, 957
Hpy99I CGWCG 1 cut(s) 673
HpyAV CCTTC 2 cut(s) 396, 686
HpyCH4III ACNGT 3 cut(s) 796, 909, 954
HpyCH4IV ACGT 2 cut(s) 95, 221
HpyF10VI GCNNNNNNNGC 4 cut(s) 36, 301, 589, 875
HpyF3I CTNAG 4 cut(s) 308, 390, 618, 642
HpySE526I ACGT 2 cut(s) 95, 221
Hsp92I GRCGYC 1 cut(s) 386
Hsp92II CATG 4 cut(s) 37, 151, 265, 976
KspI CCGCGG 1 cut(s) 285
Kzo9I GATC 3 cut(s) 274, 707, 720
LguI GCTCTTC 1 cut(s) 885
Lsp1109I GCAGC 3 cut(s) 279, 652, 658
LweI GCATC 2 cut(s) 189, 652
MaeI CTAG 4 cut(s) 336, 504, 599, 623
MaeII ACGT 2 cut(s) 95, 221
MaeIII GTNAC 5 cut(s) 91, 169, 518, 594, 835
MalI GATC 3 cut(s) 276, 709, 722
MboI GATC 3 cut(s) 274, 707, 720
MboII GAAGA 3 cut(s) 563, 702, 872
MflI RGATCY 1 cut(s) 707
MhlI GDGCHC 3 cut(s) 491, 619, 643
MlsI TGGCCA 1 cut(s) 260
MluCI AATT 3 cut(s) 115, 348, 469
MluNI TGGCCA 1 cut(s) 260
MlyI GAGTC 1 cut(s) 539
MmeI TCCRAC 1 cut(s) 636
Mox20I TGGCCA 1 cut(s) 260
MscI TGGCCA 1 cut(s) 260
MseI TTAA 2 cut(s) 72, 114
Msp20I TGGCCA 1 cut(s) 260
MspA1I CMGCKG 2 cut(s) 284, 307
MspI CCGG 5 cut(s) 230, 353, 373, 480, 925
MspR9I CCNGG 4 cut(s) 65, 373, 481, 925
Mva1269I GAATGC 1 cut(s) 505
MvaI CCWGG 1 cut(s) 65
MvnI CGCG 1 cut(s) 284
MwoI GCNNNNNNNGC 4 cut(s) 36, 301, 589, 875
NciI CCSGG 3 cut(s) 373, 481, 925
NcoI CCATGG 1 cut(s) 261
NdeII GATC 3 cut(s) 274, 707, 720
NlaIII CATG 4 cut(s) 37, 151, 265, 976
NlaIV GGNNCC 1 cut(s) 396
NmuCI GTSAC 2 cut(s) 91, 169
PciSI GCTCTTC 1 cut(s) 885
PcsI WCGNNNNNNNCGW 1 cut(s) 158
PctI GAATGC 1 cut(s) 505
PfeI GAWTC 1 cut(s) 964
PfoI TCCNGGA 1 cut(s) 63
PkrI GCNGC 7 cut(s) 41, 283, 294, 306, 648, 667, 775
PleI GAGTC 1 cut(s) 538
PpsI GAGTC 1 cut(s) 538
Psp124BI GAGCTC 1 cut(s) 491
Psp6I CCWGG 1 cut(s) 63
PspGI CCWGG 1 cut(s) 63
PspN4I GGNNCC 1 cut(s) 396
PspPI GGNCC 4 cut(s) 61, 302, 370, 395
PsuI RGATCY 1 cut(s) 707
RsaI GTAC 4 cut(s) 906, 918, 951, 958
RsaNI GTAC 4 cut(s) 905, 917, 950, 957
SacI GAGCTC 1 cut(s) 491
SacII CCGCGG 1 cut(s) 285
SapI GCTCTTC 1 cut(s) 885
SaqAI TTAA 2 cut(s) 72, 114
SatI GCNGC 7 cut(s) 40, 282, 293, 305, 647, 666, 774
Sau3AI GATC 3 cut(s) 274, 707, 720
Sau96I GGNCC 4 cut(s) 61, 302, 370, 395
SchI GAGTC 1 cut(s) 539
ScrFI CCNGG 4 cut(s) 65, 373, 481, 925
SduI GDGCHC 3 cut(s) 491, 619, 643
SfaNI GCATC 2 cut(s) 189, 652
SfcI CTRYAG 1 cut(s) 751
Sfr303I CCGCGG 1 cut(s) 285
SgrBI CCGCGG 1 cut(s) 285
SinI GGWCC 2 cut(s) 61, 395
Sse9I AATT 3 cut(s) 115, 348, 469
SsiI CCGC 7 cut(s) 39, 282, 284, 305, 566, 773, 825
SspMI CTAG 4 cut(s) 336, 504, 599, 623
SstI GAGCTC 1 cut(s) 491
StyD4I CCNGG 4 cut(s) 63, 371, 479, 923
StyI CCWWGG 1 cut(s) 261
TaaI ACNGT 3 cut(s) 796, 909, 954
TaiI ACGT 2 cut(s) 98, 224
TaqI TCGA 3 cut(s) 152, 533, 719
TasI AATT 3 cut(s) 115, 348, 469
TatI WGTACW 4 cut(s) 904, 916, 949, 956
TauI GCSGC 4 cut(s) 42, 284, 307, 776
TfiI GAWTC 1 cut(s) 964
Tru1I TTAA 2 cut(s) 72, 114
Tru9I TTAA 2 cut(s) 72, 114
TscAI CASTG 2 cut(s) 801, 959
TseFI GTSAC 2 cut(s) 91, 169
TseI GCWGC 3 cut(s) 292, 646, 665
Tsp45I GTSAC 2 cut(s) 91, 169
TspDTI ATGAA 2 cut(s) 22, 136
TspRI CASTG 2 cut(s) 801, 959
VpaK11BI GGWCC 2 cut(s) 61, 395
XapI RAATTY 2 cut(s) 348, 469
XbaI TCTAGA 1 cut(s) 335
XspI CTAG 4 cut(s) 336, 504, 599, 623
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.