Basic Information

Type: gene

Biological Identity

Species

pyrus_communis

Chromosome

Chr13

Orthogroup ID

OG0002419

Physical Location & Seq

Genomic Coordinates Reverse (-)

17328240 .. 17330409

Gene Structure 2170 bp

Loading structure...

UTR

Exon/CDS

Intron

Transcript / Protein ID

pycom13g21110.2

Sequence Viewer

CDS Protein Promoter (2k)

Length: 1392 bp

ATGGCTGGAGGAGTGTATGTTGGCGGCGGAGGAGGGAGCAGCTATGAAGGAGGTGTCACCATCTTTGTGATATTCACTTGTGTGGTGGCTGCCATGGGTGGTCTCCTCTTCGGATATGATCTCGGAATCTCAGGTGGAGTGACTTCAATGGAGTCGTTCTTGAGCAAGTTCTTCCCATCTGTGTTCCATAAAATGAAGAATGAGACTGCTAATCAAAACCAGTACTGCAAATTTGACAGCCAACTCCTCACATTGTTCACGTCTTGCCTCTACATTGCAGCCTTGGTTGCTTCCTTCTTTGCTTCATCAGTGACTAGGAAATTTGGCCGGAAAATCTCCATGTTTGTGGCAGGCCTTGTGTTTCTTCTTGGCTCTATCCTAAATGGTATTGCCAATAACATTATAGTTCTAATCATTGGTCGTCTCTTGCTTGGTATTGGTGTTGGATTTGCTAATCAGTCCGTTCCCGTTTATCTAGCGGAAATGGCTCCAACAAAGATTAGAGGAGCATTGAACATGGGGTTCCAAATGGCCATCACCATTGGTATTCTAATGGCAGGCCTTGTCAACTTTGGCACAGCCAAGATCAAGGGCGGATATGGCTGGCGAGTCTCTCTTGCTCTTGCAGCCGTTCCTTCCTTCATGATGACTCTTGCCGCAATATTTCTTCCCGACACTCCAAATTCCATCCTAGAAAGAGGTAACCCCGACAAGGCTAAGAAAATGTTGAAAAAAATCCGCGGCACCGACAACGTTGATAATGAGTTCCAAGACCTTCTTGCTGCTACTGACGCTGCCCAAAAAGTGGAAAACCAATGGACCAACATTACACAGCCGAGATATAGGCCTCAACTTGTCATTTGCATTCTCGTTCCATTCTTCCAGCAGCTCACCGGGATCAATGTAATCATGTTTTATGCACCTGTCCTTTTCATGACTTTGGGTTTTGGAGACGAAGCTTCCCTGATGTCCACAGTCATCACCGGGGGTGTTAACATGGTTGCCACCTTGGTGTCCATTCTCGCAGTTGATAAGTTTGGAAGAAGGGTGTTGTTCCTTCAAGGTGGTGTGCAGATGATCCTGTGCCAGATTGCTGTTGGAGTGATGATAGGCATGAAGTTTGGTCTCAGCGGAGTCGGATCCTTTACAAAAACTGAAGCCAATTGGATCTTGTTCTCGATCTGTGCATATGTAGCAGCGTTTGCATGGTCTTGGGGTCCGTTGGGGTGGTTGGTGCCGAGCGAGATCTGCCCTCTGGAGATCCGATCAGCCGGACAAGCCATCAACGTCTCGGTGAACATGTTCTTCACTTTTATCATTGGCCAAGTCTTCCTCAGCATGCTTTGCCACTTAAAGTTTGGTCTGTTCTTTTTCTTTGCCGGTTTTGATTGA

Functional Annotation

Gene Ontology

Molecular Function
Biological Process
Cellular Component

GO:0001678 GO:0003674 GO:0005215 GO:0005351 GO:0005354 GO:0005355 GO:0005356 GO:0005402 GO:0005575 GO:0005623 GO:0005886 GO:0006810 GO:0006811 GO:0006812 GO:0008150 GO:0008324 GO:0008643 GO:0008645 GO:0009679 GO:0009743 GO:0009746 GO:0009749 GO:0009987 GO:0010033 GO:0015075 GO:0015077 GO:0015078 GO:0015144 GO:0015145 GO:0015149 GO:0015291 GO:0015293 GO:0015294 GO:0015295 GO:0015318 GO:0015578 GO:0015672 GO:0015749 GO:0015757 GO:0015761 GO:0016020 GO:0019725 GO:0022804 GO:0022857 GO:0022890 GO:0033500 GO:0034219 GO:0034220 GO:0034284 GO:0042221 GO:0042592 GO:0042593 GO:0044464 GO:0046323 GO:0048878 GO:0050896 GO:0051119 GO:0051179 GO:0051234 GO:0051716 GO:0055055 GO:0055056 GO:0055082 GO:0055085 GO:0065007 GO:0065008 GO:0070887 GO:0071310 GO:0071322 GO:0071326 GO:0071331 GO:0071333 GO:0071702 GO:0071944 GO:0098655 GO:0098660 GO:0098662 GO:1901700 GO:1901701 GO:1902600 GO:1904659

KEGG Pathways

Metabolic & Signaling

No pathways identified.

Pfam Domains

Protein Families

Sugar_tr

Protein Analysis

464

Amino Acids

49.93

Weight (kDa)

9.13

Isoelectric Point (pI)

30.17

Instability Index

Protein Domains (Pfam)

No Pfam domains detected for this protein.

Hydrophobicity Profile (Kyte-Doolittle)

AI Structure Prediction Report

Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter

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Align Labels (Cladogram)

Image

Tree File

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Publication-ready

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Orthologous Genes (Group: OG0002419)

Species	Orthologous Gene IDs
arabidopsis_thaliana	AT1G50310 AT1G50310 AT3G19940 AT5G23270
fragaria_vesca	FvH4_2g06240 FvH4_2g06241 FvH4_2g06250
malus_domestica	MD00G1119600.v1.1 MD13G1238600.v1.1 MD13G1238700.v1.1 MD15G1433200.v1.1 MD16G1243500.v1.1
prunus_persica	Prupe.1G070800_v2.0.a1 Prupe.1G070900_v2.0.a1
pyrus_communis	pycom13g21110 pycom13g21120
rosa_chinensis	RchiOBHm_Chr4g0398701 RchiOBHm_Chr6g0256931 RchiOBHm_Chr6g0256941
rosa_laevigata	RLG00000009330 RLG00000014660 RLG00000014663
rosa_multiflora	Rmu_sc0000659.1_g000045 Rmu_sc0008600.1_g000002 Rmu_sc0017404.1_g000011
rosa_roxburghii	Rroxscaffold_5G00343660 Rroxscaffold_7G00208330 Rroxscaffold_7G00208350
rosa_rugosa	Rorug04G0010900 Rorug05G0576400 Rorug05G0576500 Rorug05G0576600
rosa_samantha	Rh4DG080100 Rh6AG095000 Rh6BG086100 Rh6BG086200 Rh6CG082200 Rh6DG077900
rosa_wichuraiana	Rw4G007340 Rw6G008110 Rw6G008130

Restriction Enzyme Sites

1 / 10

Enzyme	Recognition Site	Cut Count	Positions (bp)
AccB1I	GGYRCC	2 cut(s)	743, 1234
AccB7I	CCANNNNNTGG	1 cut(s)	805
AccII	CGCG	1 cut(s)	741
AciI	CCGC	8 cut(s)	24, 27, 479, 594, 657, 739, 741, 1131
AclI	AACGTT	1 cut(s)	753
AclWI	GGATC	6 cut(s)	905, 1072, 1134, 1147, 1175, 1255
AcoI	YGGCCR	3 cut(s)	325, 531, 1321
AcsI	RAATTY	3 cut(s)	230, 320, 682
AcuI	CTGAAG	1 cut(s)	1176
AfaI	GTAC	1 cut(s)	224
AfiI	CCNNNNNNNGG	2 cut(s)	712, 805
AflIII	ACRYGT	1 cut(s)	1299
AgsI	TTSAA	4 cut(s)	147, 514, 730, 1061
AjiI	CACGTC	1 cut(s)	261
AleI	CACNNNNGTG	2 cut(s)	80, 1010
AluBI	AGCT	3 cut(s)	42, 889, 959
AluI	AGCT	3 cut(s)	42, 889, 959
Alw26I	GTCTC	7 cut(s)	107, 197, 428, 616, 945, 1130, 1294
AlwI	GGATC	6 cut(s)	905, 1072, 1134, 1147, 1175, 1255
AoxI	GGCC	6 cut(s)	325, 352, 531, 559, 845, 1321
ApeKI	GCWGC	8 cut(s)	39, 89, 278, 626, 782, 794, 886, 1196
ApoI	RAATTY	3 cut(s)	230, 320, 682
Asp700I	GAANNNNTTC	1 cut(s)	1301
AspS9I	GGNCC	2 cut(s)	819, 1217
AsuC2I	CCSGG	2 cut(s)	895, 985
AsuHPI	GGTGA	5 cut(s)	49, 529, 883, 973, 1306
AvaII	GGWCC	2 cut(s)	819, 1217
BalI	TGGCCA	2 cut(s)	533, 1323
BamHI	GGATCC	1 cut(s)	1139
BanI	GGYRCC	2 cut(s)	743, 1234
BbsI	GAAGAC	1 cut(s)	1321
BbvCI	CCTCAGC	1 cut(s)	1334
BbvI	GCAGC	8 cut(s)	51, 76, 290, 638, 769, 781, 898, 1208
BccI	CCATC	5 cut(s)	68, 184, 542, 695, 1289
BceAI	ACGGC	1 cut(s)	614
BcnI	CCSGG	2 cut(s)	895, 985
BcoDI	GTCTC	7 cut(s)	107, 197, 428, 616, 945, 1130, 1294
BfaI	CTAG	3 cut(s)	315, 476, 692
BglII	AGATCT	1 cut(s)	1245
BmcAI	AGTACT	1 cut(s)	224
Bme1390I	CCNGG	2 cut(s)	895, 985
Bme18I	GGWCC	2 cut(s)	819, 1217
BmgBI	CACGTC	1 cut(s)	261
BmgT120I	GGNCC	2 cut(s)	819, 1217
BmiI	GGNNCC	6 cut(s)	489, 524, 745, 1141, 1218, 1236
BmrFI	CCNGG	2 cut(s)	895, 985
BpiI	GAAGAC	1 cut(s)	1321
BpmI	CTGGAG	2 cut(s)	27, 1277
Bpu10I	CCTNAGC	1 cut(s)	1334
BpuEI	CTTGAG	1 cut(s)	181
BpuMI	CCSGG	2 cut(s)	895, 985
BsaI	GGTCTC	2 cut(s)	107, 1130
BsaJI	CCNNGG	5 cut(s)	93, 282, 739, 984, 1008
BsaXI	ACNNNNNCTCC	1 cut(s)	33
Bsc4I	CCNNNNNNNGG	2 cut(s)	712, 805
Bse118I	RCCGGY	1 cut(s)	1379
Bse1I	ACTGG	1 cut(s)	220
Bse3DI	GCAATG	1 cut(s)	273
BseDI	CCNNGG	5 cut(s)	93, 282, 739, 984, 1008
BseGI	GGATG	1 cut(s)	687
BseLI	CCNNNNNNNGG	2 cut(s)	712, 805
BseMI	GCAATG	1 cut(s)	273
BseMII	CTCAG	3 cut(s)	144, 1141, 1348
BseNI	ACTGG	1 cut(s)	220
BseRI	GAGGAG	5 cut(s)	24, 45, 95, 236, 519
BseXI	GCAGC	8 cut(s)	51, 76, 290, 638, 769, 781, 898, 1208
BsgI	GTGCAG	1 cut(s)	1091
Bsh1236I	CGCG	1 cut(s)	741
BshFI	GGCC	6 cut(s)	327, 354, 533, 561, 847, 1323
BshNI	GGYRCC	2 cut(s)	743, 1234
BsiSI	CCGG	5 cut(s)	328, 894, 984, 1272, 1380
BslI	CCNNNNNNNGG	2 cut(s)	712, 805
BsmAI	GTCTC	7 cut(s)	107, 197, 428, 616, 945, 1130, 1294
BsmBI	CGTCTC	3 cut(s)	428, 945, 1294
BsmI	GAATGC	1 cut(s)	864
BsnI	GGCC	6 cut(s)	327, 354, 533, 561, 847, 1323
Bso31I	GGTCTC	2 cut(s)	107, 1130
Bsp19I	CCATGG	1 cut(s)	93
BspACI	CCGC	8 cut(s)	24, 27, 479, 594, 657, 739, 741, 1131
BspANI	GGCC	6 cut(s)	327, 354, 533, 561, 847, 1323
BspCNI	CTCAG	3 cut(s)	143, 1140, 1347
BspFNI	CGCG	1 cut(s)	741
BspHI	TCATGA	2 cut(s)	642, 933
BspLI	GGNNCC	6 cut(s)	489, 524, 745, 1141, 1218, 1236
BspPI	GGATC	6 cut(s)	905, 1072, 1134, 1147, 1175, 1255
BspT107I	GGYRCC	2 cut(s)	743, 1234
BspTNI	GGTCTC	2 cut(s)	107, 1130
BsrDI	GCAATG	1 cut(s)	273
BsrFI	RCCGGY	1 cut(s)	1379
BsrI	ACTGG	1 cut(s)	220
BssAI	RCCGGY	1 cut(s)	1379
BssECI	CCNNGG	5 cut(s)	93, 282, 739, 984, 1008
BssT1I	CCWWGG	3 cut(s)	93, 282, 1008
Bst4CI	ACNGT	1 cut(s)	976
Bst6I	CTCTTC	1 cut(s)	113
BstAPI	GCANNNNNTGC	2 cut(s)	1202, 1344
BstC8I	GCNNGC	4 cut(s)	352, 559, 605, 1340
BstDEI	CTNAG	4 cut(s)	130, 717, 1127, 1334
BstDSI	CCRYGG	2 cut(s)	93, 739
BstEII	GGTNACC	1 cut(s)	701
BstF5I	GGATG	1 cut(s)	687
BstFNI	CGCG	1 cut(s)	741
BstMAI	GTCTC	7 cut(s)	107, 197, 428, 616, 945, 1130, 1294
BstNSI	RCATGY	2 cut(s)	1303, 1342
BstPI	GGTNACC	1 cut(s)	701
BstSCI	CCNGG	2 cut(s)	893, 983
BstUI	CGCG	1 cut(s)	741
BstV1I	GCAGC	8 cut(s)	51, 76, 290, 638, 769, 781, 898, 1208
BstV2I	GAAGAC	1 cut(s)	1321
BstX2I	RGATCY	4 cut(s)	1139, 1167, 1245, 1260
BstXI	CCANNNNNNTGG	1 cut(s)	346
BstYI	RGATCY	4 cut(s)	1139, 1167, 1245, 1260
BsuRI	GGCC	6 cut(s)	327, 354, 533, 561, 847, 1323
BtgI	CCRYGG	2 cut(s)	93, 739
BtrI	CACGTC	1 cut(s)	261
BtsCI	GGATG	1 cut(s)	687
BtsIMutI	CAGTG	1 cut(s)	315
Cac8I	GCNNGC	4 cut(s)	352, 559, 605, 1340
CciI	TCATGA	2 cut(s)	642, 933
Cfr10I	RCCGGY	1 cut(s)	1379
Cfr13I	GGNCC	2 cut(s)	819, 1217
Cfr42I	CCGCGG	1 cut(s)	742
CseI	GACGC	1 cut(s)	800
Csp6I	GTAC	1 cut(s)	223
CviQI	GTAC	1 cut(s)	223
DdeI	CTNAG	4 cut(s)	130, 717, 1127, 1334
EaeI	YGGCCR	3 cut(s)	325, 531, 1321
Eam1104I	CTCTTC	1 cut(s)	113
EarI	CTCTTC	1 cut(s)	113
EciI	GGCGGA	2 cut(s)	42, 609
Eco130I	CCWWGG	3 cut(s)	93, 282, 1008
Eco147I	AGGCCT	3 cut(s)	354, 561, 847
Eco31I	GGTCTC	2 cut(s)	107, 1130
Eco47I	GGWCC	2 cut(s)	819, 1217
Eco57I	CTGAAG	1 cut(s)	1176
Eco91I	GGTNACC	1 cut(s)	701
EcoO65I	GGTNACC	1 cut(s)	701
EcoT14I	CCWWGG	3 cut(s)	93, 282, 1008
ErhI	CCWWGG	3 cut(s)	93, 282, 1008
Esp3I	CGTCTC	3 cut(s)	428, 945, 1294
FalI	AAGNNNNNCTT	2 cut(s)	762, 794
FauNDI	CATATG	1 cut(s)	1189
FokI	GGATG	1 cut(s)	674
FspBI	CTAG	3 cut(s)	315, 476, 692
GsuI	CTGGAG	2 cut(s)	27, 1277
HaeIII	GGCC	6 cut(s)	327, 354, 533, 561, 847, 1323
HapII	CCGG	5 cut(s)	328, 894, 984, 1272, 1380
HgaI	GACGC	1 cut(s)	800
HincII	GTYRAC	2 cut(s)	568, 994
HindII	GTYRAC	2 cut(s)	568, 994
HindIII	AAGCTT	1 cut(s)	957
HinfI	GANTC	5 cut(s)	126, 152, 609, 649, 1134
HpaI	GTTAAC	1 cut(s)	994
HpaII	CCGG	5 cut(s)	328, 894, 984, 1272, 1380
HphI	GGTGA	5 cut(s)	49, 529, 883, 973, 1306
Hpy166II	GTNNAC	5 cut(s)	258, 568, 972, 994, 1297
Hpy188I	TCNGA	4 cut(s)	113, 125, 1139, 1265
Hpy188III	TCNNGA	6 cut(s)	160, 643, 671, 934, 1177, 1256
Hpy8I	GTNNAC	5 cut(s)	258, 568, 972, 994, 1297
HpyAV	CCTTC	7 cut(s)	41, 304, 645, 649, 785, 1038, 1067
HpyCH4III	ACNGT	1 cut(s)	976
HpyCH4IV	ACGT	3 cut(s)	260, 753, 1287
HpyCH4V	TGCA	8 cut(s)	228, 278, 626, 864, 920, 1072, 1187, 1205
HpyF3I	CTNAG	4 cut(s)	130, 717, 1127, 1334
HpySE526I	ACGT	3 cut(s)	260, 753, 1287
KspAI	GTTAAC	1 cut(s)	994
KspI	CCGCGG	1 cut(s)	742
LmnI	GCTCC	3 cut(s)	36, 493, 506
Lsp1109I	GCAGC	8 cut(s)	51, 76, 290, 638, 769, 781, 898, 1208
MaeI	CTAG	3 cut(s)	315, 476, 692
MaeII	ACGT	3 cut(s)	260, 753, 1287
MaeIII	GTNAC	4 cut(s)	55, 139, 310, 701
MboII	GAAGA	9 cut(s)	100, 163, 208, 356, 659, 871, 1053, 1297, 1321
MfeI	CAATTG	1 cut(s)	1162
MflI	RGATCY	4 cut(s)	1139, 1167, 1245, 1260
MlsI	TGGCCA	2 cut(s)	533, 1323
MluCI	AATT	4 cut(s)	230, 320, 682, 1162
MluNI	TGGCCA	2 cut(s)	533, 1323
MlyI	GAGTC	4 cut(s)	161, 618, 643, 1143
MmeI	TCCRAC	4 cut(s)	424, 515, 1078, 1117
Mox20I	TGGCCA	2 cut(s)	533, 1323
MroXI	GAANNNNTTC	1 cut(s)	1301
MscI	TGGCCA	2 cut(s)	533, 1323
MseI	TTAA	2 cut(s)	993, 1352
MslI	CAYNNNNRTG	4 cut(s)	65, 80, 344, 1010
Msp20I	TGGCCA	2 cut(s)	533, 1323
MspA1I	CMGCKG	2 cut(s)	741, 1131
MspI	CCGG	5 cut(s)	328, 894, 984, 1272, 1380
MspR9I	CCNGG	2 cut(s)	895, 985
MunI	CAATTG	1 cut(s)	1162
Mva1269I	GAATGC	1 cut(s)	864
MvnI	CGCG	1 cut(s)	741
NciI	CCSGG	2 cut(s)	895, 985
NcoI	CCATGG	1 cut(s)	93
NdeI	CATATG	1 cut(s)	1189
NlaIV	GGNNCC	6 cut(s)	489, 524, 745, 1141, 1218, 1236
NmeAIII	GCCGAG	2 cut(s)	861, 1263
NmuCI	GTSAC	3 cut(s)	55, 139, 310
NspI	RCATGY	2 cut(s)	1303, 1342
OliI	CACNNNNGTG	2 cut(s)	80, 1010
PaeI	GCATGC	1 cut(s)	1342
PagI	TCATGA	2 cut(s)	642, 933
PceI	AGGCCT	3 cut(s)	354, 561, 847
PciI	ACATGT	1 cut(s)	1299
PctI	GAATGC	1 cut(s)	864
PdmI	GAANNNNTTC	1 cut(s)	1301
PfeI	GAWTC	1 cut(s)	126
PflMI	CCANNNNNTGG	1 cut(s)	805
PleI	GAGTC	4 cut(s)	160, 617, 643, 1142
PpsI	GAGTC	4 cut(s)	160, 617, 643, 1142
PscI	ACATGT	1 cut(s)	1299
Psp1406I	AACGTT	1 cut(s)	753
PspEI	GGTNACC	1 cut(s)	701
PspN4I	GGNNCC	6 cut(s)	489, 524, 745, 1141, 1218, 1236
PspPI	GGNCC	2 cut(s)	819, 1217
PsuI	RGATCY	4 cut(s)	1139, 1167, 1245, 1260
RsaI	GTAC	1 cut(s)	224
RsaNI	GTAC	1 cut(s)	223
RseI	CAYNNNNRTG	4 cut(s)	65, 80, 344, 1010
SacII	CCGCGG	1 cut(s)	742
SaqAI	TTAA	2 cut(s)	993, 1352
Sau96I	GGNCC	2 cut(s)	819, 1217
ScaI	AGTACT	1 cut(s)	224
SchI	GAGTC	4 cut(s)	161, 618, 643, 1143
ScrFI	CCNGG	2 cut(s)	895, 985
Sfr303I	CCGCGG	1 cut(s)	742
SgrBI	CCGCGG	1 cut(s)	742
SinI	GGWCC	2 cut(s)	819, 1217
SmiMI	CAYNNNNRTG	4 cut(s)	65, 80, 344, 1010
SmlI	CTYRAG	1 cut(s)	160
SmoI	CTYRAG	1 cut(s)	160
SphI	GCATGC	1 cut(s)	1342
Sse9I	AATT	4 cut(s)	230, 320, 682, 1162
SseBI	AGGCCT	3 cut(s)	354, 561, 847
SsiI	CCGC	8 cut(s)	24, 27, 479, 594, 657, 739, 741, 1131
SspI	AATATT	1 cut(s)	663
SspMI	CTAG	3 cut(s)	315, 476, 692
StuI	AGGCCT	3 cut(s)	354, 561, 847
StyD4I	CCNGG	2 cut(s)	893, 983
StyI	CCWWGG	3 cut(s)	93, 282, 1008
TaaI	ACNGT	1 cut(s)	976
TaiI	ACGT	3 cut(s)	263, 756, 1290
TaqI	TCGA	1 cut(s)	1178
TasI	AATT	4 cut(s)	230, 320, 682, 1162
TatI	WGTACW	1 cut(s)	222
TauI	GCSGC	3 cut(s)	27, 659, 744
TfiI	GAWTC	1 cut(s)	126
Tru1I	TTAA	2 cut(s)	993, 1352
Tru9I	TTAA	2 cut(s)	993, 1352
TscAI	CASTG	1 cut(s)	315
TseFI	GTSAC	3 cut(s)	55, 139, 310
TseI	GCWGC	8 cut(s)	39, 89, 278, 626, 782, 794, 886, 1196
Tsp45I	GTSAC	3 cut(s)	55, 139, 310
TspDTI	ATGAA	6 cut(s)	60, 209, 294, 631, 922, 1130
TspGWI	ACGGA	2 cut(s)	451, 1209
TspRI	CASTG	1 cut(s)	315
Van91I	CCANNNNNTGG	1 cut(s)	805
VpaK11BI	GGWCC	2 cut(s)	819, 1217
XapI	RAATTY	3 cut(s)	230, 320, 682
XceI	RCATGY	2 cut(s)	1303, 1342
XcmI	CCANNNNNNNNNTGG	2 cut(s)	1094, 1355
XmnI	GAANNNNTTC	1 cut(s)	1301
XspI	CTAG	3 cut(s)	315, 476, 692
ZrmI	AGTACT	1 cut(s)	224

Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.