RLG00000002473

Tyrosyl-DNA phosphodiesterase

Design Primers CRISPR Design

Basic Information

Type: gene
Biological Identity
rosa_laevigata
Chr1
OG0006613
Physical Location & Seq
Forward (+)
34796707 .. 34799253
2547 bp
Loading structure...
UTR
Exon/CDS
Intron
RLM00000002473

Sequence Viewer

Length: 1332 bp
ATGCAGCACTGTGATAGAGTAGTGTCTTCAGAATCGGACAGTGACTTAGCTGCTCTCTGTGTGCAAGGTGATGGTTTAGATCTGCAAGACGATGAAGTCCAAGTTCCTTCTGACACTCGTGTTGCTGATGGAAATTTTGGGACTTCATCTTTCAATTTGAGAAGCACGGATAATCTTCCTCATGTTGGCGATTTTGTTAAGGATAAGACTTGCAGCAAGAATGTTGGTCTACAACCTAGCAAGAACTTCTACCTGAATCGCCTTGCGTTTGAGGACCAGAGCTCTTCAAGTTGTCATTCTGTTATTTCCTTGCCAGAGCTTCTTCATCCTGTTCAAAGTATATCACAAATATTTATTGCAACGTTCACAAGTGACATTTTATGGGTTTTGTCAACCTGTGAGATTCCTAGCCATCTGCCAGTAACAGTTGCTTGCCATAATACAGAGAGATGTTGGAGTTCAAGCACTGAAAATAGAACATCTGCACCTTACCCAGAATTTCCAAACTTAGTTGTAGTGTATCCCCCGTTCCCTGAGGCCATAGCTTTTGGTGAAGACCTGAAAAGACATGGCATTGGTTGCCATCATCCAAAACTGTTTGTTTTACAGAGAGATGATAATATTTGTGTTATCATTACCTCCGCAAATTTAGTGCCAACACAGTGGAATGCAGTAACCAATACCATCTGGTGGCAAGATTTCCCTCGCAGAAGTGCTCCTGATTATTCATCACTTTTTACTCAATTTCCCGGCGGGGAAGTAAATCAAGACTCAAAATCGGATTTTGCTTCTCATTTGGCTGGATTTATAGCAACTCTACTGACCGATGTACCAAGTCATGCCCAAGGCAATGGGACATTTGTTGCTTCTGTACCTGGAATCCATTCATATAAAACTCCCTATATAATGGAATCCAGACACTATGCCTGTGCTGAATGTGGTCCATCAGGTTCATCTGGTATGAAATTCCTCGTATCAGTTGAAGCAGCTGTGGTTGGTCTGAGCTACCTCTTTCACAATGCAACAGATGCCAATGGTGCAAAGCTGAAGAAACTGGCTTCATTTCTCAGGAAATCTTGTGAAAATGCGAAAGACTTATCAATTGTCTTAACAAGAAACACAAACATACCTGCAGATGCAAATGCAGTGAGCATTCATGTGTCGAATCATATTGAGTTCTCTGAGGGAGATTACATTCAACTTGGGTTTTTACCTAGAAACATTGCAAAATGGGTCTCTCCGCTCTGGGATATTGGAATGTTTAGATTCTCGGGTTATGTCTGTCCTAAGGAAGCCCTTGGAGCAGCTTTAGGAGACACTTGGAGCAATTAG
Functional Annotation
Gene Ontology
Molecular Function
Biological Process
Cellular Component
No ontology terms assigned.
KEGG Pathways
Metabolic & Signaling
No pathways identified.
Pfam Domains
Protein Families
FHA HIRAN Tyr-DNA_phospho

Protein Analysis

444

Amino Acids

48.51

Weight (kDa)

5.45

Isoelectric Point (pI)

52.42

Instability Index
Protein Domains (Pfam)
Domain Name Pfam ID Position E-value Description
Tyr-DNA_phospho PF06087 92 - 296 1.5e-15 Tyrosyl-DNA phosphodiesterase
HIRAN PF08797 367 - 432 1.8e-09 HIRAN domain
Hydrophobicity Profile (Kyte-Doolittle)
AI Structure Prediction Report
Calculating structure properties...

Genomic Context

Gene Family Tree

Species Filter
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Publication-ready
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Restriction Enzyme Sites

1 / 10
Enzyme Recognition Site Cut Count Positions (bp)
AasI GACNNNNNNGTC 1 cut(s) 95
Acc36I ACCTGC 1 cut(s) 1138
AccB7I CCANNNNNTGG 1 cut(s) 690
AccBSI CCGCTC 1 cut(s) 1243
AccI GTMKAC 1 cut(s) 229
AciI CCGC 3 cut(s) 642, 753, 1241
AclI AACGTT 1 cut(s) 362
AcsI RAATTY 4 cut(s) 133, 497, 646, 965
AcuI CTGAAG 2 cut(s) 12, 1067
AfaI GTAC 2 cut(s) 831, 873
AfiI CCNNNNNNNGG 2 cut(s) 185, 690
AgsI TTSAA 6 cut(s) 154, 288, 335, 462, 983, 1199
AjnI CCWGG 1 cut(s) 874
AluBI AGCT 8 cut(s) 50, 282, 319, 545, 989, 1005, 1045, 1307
AluI AGCT 8 cut(s) 50, 282, 319, 545, 989, 1005, 1045, 1307
Alw21I GWGCWC 2 cut(s) 284, 718
Alw26I GTCTC 2 cut(s) 1240, 1308
Ama87I CYCGRG 1 cut(s) 1270
AoxI GGCC 1 cut(s) 537
ApeKI GCWGC 5 cut(s) 4, 50, 213, 986, 1304
ApoI RAATTY 4 cut(s) 133, 497, 646, 965
Asp700I GAANNNNTTC 1 cut(s) 883
AspS9I GGNCC 2 cut(s) 274, 941
AsuC2I CCSGG 1 cut(s) 750
AsuHPI GGTGA 2 cut(s) 80, 563
AvaI CYCGRG 1 cut(s) 1270
AvaII GGWCC 2 cut(s) 274, 941
AxyI CCTNAGG 2 cut(s) 534, 1287
BaeI ACNNNNGTAYC 2 cut(s) 813, 846
BanII GRGCYC 1 cut(s) 284
BauI CACGAG 1 cut(s) 117
BbsI GAAGAC 2 cut(s) 18, 561
Bbv12I GWGCWC 2 cut(s) 284, 718
BbvI GCAGC 5 cut(s) 16, 37, 225, 998, 1316
BccI CCATC 6 cut(s) 65, 122, 420, 591, 692, 952
BciT130I CCWGG 1 cut(s) 876
BciVI GTATCC 1 cut(s) 531
BcnI CCSGG 1 cut(s) 750
BcoDI GTCTC 2 cut(s) 1240, 1308
BfaI CTAG 3 cut(s) 237, 408, 1215
BfmI CTRYAG 1 cut(s) 1131
BfuAI ACCTGC 1 cut(s) 1138
BfuI GTATCC 1 cut(s) 531
BglII AGATCT 1 cut(s) 79
BisI GCNGC 5 cut(s) 5, 51, 214, 987, 1305
BlsI GCNGC 5 cut(s) 6, 52, 215, 988, 1306
Bme1390I CCNGG 2 cut(s) 750, 876
Bme18I GGWCC 2 cut(s) 274, 941
BmeT110I CYCGRG 1 cut(s) 1270
BmgT120I GGNCC 2 cut(s) 274, 941
BmrFI CCNGG 2 cut(s) 750, 876
BmsI GCATC 2 cut(s) 1018, 1126
BpiI GAAGAC 2 cut(s) 18, 561
BpuMI CCSGG 1 cut(s) 750
BsaI GGTCTC 1 cut(s) 1240
BsaJI CCNNGG 2 cut(s) 844, 1297
Bsc4I CCNNNNNNNGG 2 cut(s) 185, 690
Bse1I ACTGG 2 cut(s) 419, 1059
Bse21I CCTNAGG 2 cut(s) 534, 1287
Bse3DI GCAATG 2 cut(s) 856, 1221
BseBI CCWGG 1 cut(s) 876
BseDI CCNNGG 2 cut(s) 844, 1297
BseGI GGATG 2 cut(s) 325, 586
BseLI CCNNNNNNNGG 2 cut(s) 185, 690
BseMI GCAATG 2 cut(s) 856, 1221
BseMII CTCAG 4 cut(s) 525, 992, 1081, 1173
BseNI ACTGG 2 cut(s) 419, 1059
BseXI GCAGC 5 cut(s) 16, 37, 225, 998, 1316
BsgI GTGCAG 1 cut(s) 468
BshFI GGCC 1 cut(s) 539
BsiHKAI GWGCWC 2 cut(s) 284, 718
BsiHKCI CYCGRG 1 cut(s) 1270
BsiSI CCGG 1 cut(s) 750
BslFI GGGAC 2 cut(s) 154, 868
BslI CCNNNNNNNGG 2 cut(s) 185, 690
BsmAI GTCTC 2 cut(s) 1240, 1308
BsmFI GGGAC 2 cut(s) 154, 868
BsmI GAATGC 2 cut(s) 673, 1152
BsnI GGCC 1 cut(s) 539
Bso31I GGTCTC 1 cut(s) 1240
BsoBI CYCGRG 1 cut(s) 1270
Bsp1286I GDGCHC 2 cut(s) 284, 718
Bsp143I GATC 1 cut(s) 79
BspACI CCGC 3 cut(s) 642, 753, 1241
BspANI GGCC 1 cut(s) 539
BspCNI CTCAG 4 cut(s) 526, 993, 1080, 1174
BspMAI CTGCAG 1 cut(s) 1135
BspMI ACCTGC 1 cut(s) 1138
BspQI GCTCTTC 1 cut(s) 289
BspTNI GGTCTC 1 cut(s) 1240
BsrBI CCGCTC 1 cut(s) 1243
BsrDI GCAATG 2 cut(s) 856, 1221
BsrI ACTGG 2 cut(s) 419, 1059
BssECI CCNNGG 2 cut(s) 844, 1297
BssMI GATC 1 cut(s) 79
BssSI CACGAG 1 cut(s) 117
BssT1I CCWWGG 2 cut(s) 844, 1297
Bst2BI CACGAG 1 cut(s) 117
Bst2UI CCWGG 1 cut(s) 876
Bst4CI ACNGT 5 cut(s) 11, 41, 427, 597, 663
Bst6I CTCTTC 1 cut(s) 289
BstAPI GCANNNNNTGC 2 cut(s) 579, 1028
BstC8I GCNNGC 1 cut(s) 433
BstDEI CTNAG 7 cut(s) 46, 508, 534, 1001, 1067, 1182, 1287
BstF5I GGATG 2 cut(s) 325, 586
BstKTI GATC 1 cut(s) 82
BstMAI GTCTC 2 cut(s) 1240, 1308
BstMBI GATC 1 cut(s) 79
BstMWI GCNNNNNNNGC 4 cut(s) 579, 1028, 1037, 1301
BstNI CCWGG 1 cut(s) 876
BstSCI CCNGG 2 cut(s) 748, 874
BstSFI CTRYAG 1 cut(s) 1131
BstV1I GCAGC 5 cut(s) 16, 37, 225, 998, 1316
BstV2I GAAGAC 2 cut(s) 18, 561
BstX2I RGATCY 1 cut(s) 79
BstXI CCANNNNNNTGG 2 cut(s) 663, 851
BstYI RGATCY 1 cut(s) 79
Bsu36I CCTNAGG 2 cut(s) 534, 1287
BsuI GTATCC 1 cut(s) 531
BsuRI GGCC 1 cut(s) 539
BtsCI GGATG 2 cut(s) 325, 586
BtsI GCAGTG 1 cut(s) 1152
BtsIMutI CAGTG 5 cut(s) 7, 46, 465, 668, 1152
BveI ACCTGC 1 cut(s) 1138
Cac8I GCNNGC 1 cut(s) 433
Cfr13I GGNCC 2 cut(s) 274, 941
Csp6I GTAC 2 cut(s) 830, 872
CviAII CATG 4 cut(s) 182, 569, 839, 1157
CviQI GTAC 2 cut(s) 830, 872
DdeI CTNAG 7 cut(s) 46, 508, 534, 1001, 1067, 1182, 1287
DpnI GATC 1 cut(s) 81
DpnII GATC 1 cut(s) 79
DrdI GACNNNNNNGTC 1 cut(s) 95
DseDI GACNNNNNNGTC 1 cut(s) 95
Eam1104I CTCTTC 1 cut(s) 289
EarI CTCTTC 1 cut(s) 289
Ecl136II GAGCTC 1 cut(s) 282
Eco130I CCWWGG 2 cut(s) 844, 1297
Eco24I GRGCYC 1 cut(s) 284
Eco31I GGTCTC 1 cut(s) 1240
Eco47I GGWCC 2 cut(s) 274, 941
Eco53kI GAGCTC 1 cut(s) 282
Eco57I CTGAAG 2 cut(s) 12, 1067
Eco81I CCTNAGG 2 cut(s) 534, 1287
Eco88I CYCGRG 1 cut(s) 1270
EcoICRI GAGCTC 1 cut(s) 282
EcoRII CCWGG 1 cut(s) 874
EcoT14I CCWWGG 2 cut(s) 844, 1297
EcoT38I GRGCYC 1 cut(s) 284
ErhI CCWWGG 2 cut(s) 844, 1297
FaeI CATG 4 cut(s) 185, 572, 842, 1160
FaqI GGGAC 2 cut(s) 154, 868
FatI CATG 4 cut(s) 181, 568, 838, 1156
FauI CCCGC 1 cut(s) 746
FblI GTMKAC 1 cut(s) 229
Fnu4HI GCNGC 5 cut(s) 5, 51, 214, 987, 1305
FokI GGATG 2 cut(s) 312, 573
FriOI GRGCYC 1 cut(s) 284
Fsp4HI GCNGC 5 cut(s) 5, 51, 214, 987, 1305
FspBI CTAG 3 cut(s) 237, 408, 1215
GluI GCNGC 5 cut(s) 5, 51, 214, 987, 1305
HaeIII GGCC 1 cut(s) 539
HapII CCGG 1 cut(s) 750
Hin1II CATG 4 cut(s) 185, 572, 842, 1160
HincII GTYRAC 1 cut(s) 393
HindII GTYRAC 1 cut(s) 393
HinfI GANTC 8 cut(s) 32, 256, 403, 770, 879, 911, 1165, 1266
HpaII CCGG 1 cut(s) 750
HphI GGTGA 2 cut(s) 80, 563
Hpy166II GTNNAC 3 cut(s) 230, 366, 393
Hpy188I TCNGA 6 cut(s) 31, 37, 112, 781, 1002, 1183
Hpy188III TCNNGA 4 cut(s) 719, 767, 915, 1069
Hpy8I GTNNAC 3 cut(s) 230, 366, 393
HpyAV CCTTC 1 cut(s) 117
HpyCH4III ACNGT 5 cut(s) 11, 41, 427, 597, 663
HpyCH4IV ACGT 1 cut(s) 362
HpyF10VI GCNNNNNNNGC 4 cut(s) 579, 1028, 1037, 1301
HpyF3I CTNAG 7 cut(s) 46, 508, 534, 1001, 1067, 1182, 1287
HpySE526I ACGT 1 cut(s) 362
Hsp92II CATG 4 cut(s) 185, 572, 842, 1160
Kzo9I GATC 1 cut(s) 79
LguI GCTCTTC 1 cut(s) 289
LmnI GCTCC 3 cut(s) 721, 1301, 1323
Lsp1109I GCAGC 5 cut(s) 16, 37, 225, 998, 1316
LweI GCATC 2 cut(s) 1018, 1126
MaeI CTAG 3 cut(s) 237, 408, 1215
MaeII ACGT 1 cut(s) 362
MaeIII GTNAC 4 cut(s) 41, 371, 421, 673
MalI GATC 1 cut(s) 81
MbiI CCGCTC 1 cut(s) 1243
MboI GATC 1 cut(s) 79
MboII GAAGA 6 cut(s) 18, 167, 276, 314, 566, 1060
MfeI CAATTG 1 cut(s) 1101
MflI RGATCY 1 cut(s) 79
MhlI GDGCHC 2 cut(s) 284, 718
MluCI AATT 8 cut(s) 133, 154, 497, 646, 743, 965, 1101, 1327
MlyI GAGTC 1 cut(s) 764
MmeI TCCRAC 1 cut(s) 434
MnlI CCTC 8 cut(s) 189, 265, 529, 649, 714, 980, 1019, 1177
MroXI GAANNNNTTC 1 cut(s) 883
MseI TTAA 2 cut(s) 198, 1109
MslI CAYNNNNRTG 1 cut(s) 1157
MspA1I CMGCKG 1 cut(s) 989
MspI CCGG 1 cut(s) 750
MspR9I CCNGG 2 cut(s) 750, 876
MunI CAATTG 1 cut(s) 1101
Mva1269I GAATGC 2 cut(s) 673, 1152
MvaI CCWGG 1 cut(s) 876
MwoI GCNNNNNNNGC 4 cut(s) 579, 1028, 1037, 1301
NciI CCSGG 1 cut(s) 750
NdeII GATC 1 cut(s) 79
NlaIII CATG 4 cut(s) 185, 572, 842, 1160
NmuCI GTSAC 2 cut(s) 41, 371
PciSI GCTCTTC 1 cut(s) 289
PctI GAATGC 2 cut(s) 673, 1152
PdmI GAANNNNTTC 1 cut(s) 883
PfeI GAWTC 7 cut(s) 32, 256, 403, 879, 911, 1165, 1266
PflMI CCANNNNNTGG 1 cut(s) 690
PkrI GCNGC 5 cut(s) 6, 52, 215, 988, 1306
PleI GAGTC 1 cut(s) 764
PpsI GAGTC 1 cut(s) 764
Psp124BI GAGCTC 1 cut(s) 284
Psp1406I AACGTT 1 cut(s) 362
Psp6I CCWGG 1 cut(s) 874
PspGI CCWGG 1 cut(s) 874
PspPI GGNCC 2 cut(s) 274, 941
PsrI GAACNNNNNNTAC 2 cut(s) 512, 544
PstI CTGCAG 1 cut(s) 1135
PsuI RGATCY 1 cut(s) 79
PvuII CAGCTG 1 cut(s) 989
RsaI GTAC 2 cut(s) 831, 873
RsaNI GTAC 2 cut(s) 830, 872
RseI CAYNNNNRTG 1 cut(s) 1157
SacI GAGCTC 1 cut(s) 284
SapI GCTCTTC 1 cut(s) 289
SaqAI TTAA 2 cut(s) 198, 1109
SatI GCNGC 5 cut(s) 5, 51, 214, 987, 1305
Sau3AI GATC 1 cut(s) 79
Sau96I GGNCC 2 cut(s) 274, 941
SchI GAGTC 1 cut(s) 764
ScrFI CCNGG 2 cut(s) 750, 876
SduI GDGCHC 2 cut(s) 284, 718
SfaNI GCATC 2 cut(s) 1018, 1126
SfcI CTRYAG 1 cut(s) 1131
SinI GGWCC 2 cut(s) 274, 941
SmiMI CAYNNNNRTG 1 cut(s) 1157
Sse9I AATT 8 cut(s) 133, 154, 497, 646, 743, 965, 1101, 1327
SsiI CCGC 3 cut(s) 642, 753, 1241
SspI AATATT 2 cut(s) 351, 622
SspMI CTAG 3 cut(s) 237, 408, 1215
SstI GAGCTC 1 cut(s) 284
StyD4I CCNGG 2 cut(s) 748, 874
StyI CCWWGG 2 cut(s) 844, 1297
TaaI ACNGT 5 cut(s) 11, 41, 427, 597, 663
TaiI ACGT 1 cut(s) 365
TaqI TCGA 1 cut(s) 1163
TaqII GACCGA 1 cut(s) 839
TasI AATT 8 cut(s) 133, 154, 497, 646, 743, 965, 1101, 1327
TfiI GAWTC 7 cut(s) 32, 256, 403, 879, 911, 1165, 1266
Tru1I TTAA 2 cut(s) 198, 1109
Tru9I TTAA 2 cut(s) 198, 1109
TscAI CASTG 5 cut(s) 14, 46, 472, 668, 1152
TseFI GTSAC 2 cut(s) 41, 371
TseI GCWGC 5 cut(s) 4, 50, 213, 986, 1304
Tsp45I GTSAC 2 cut(s) 41, 371
TspDTI ATGAA 9 cut(s) 108, 135, 314, 717, 876, 942, 977, 1050, 1145
TspGWI ACGGA 1 cut(s) 182
TspRI CASTG 5 cut(s) 14, 46, 472, 668, 1152
Van91I CCANNNNNTGG 1 cut(s) 690
VpaK11BI GGWCC 2 cut(s) 274, 941
XapI RAATTY 4 cut(s) 133, 497, 646, 965
XmiI GTMKAC 1 cut(s) 229
XmnI GAANNNNTTC 1 cut(s) 883
XspI CTAG 3 cut(s) 237, 408, 1215
Using CommOnly database (standard laboratory enzymes). Scanned on CDS sequence.